Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncargo receptor activity

VLDLR SSC5D FOLR1 ENPP2 LRP1 LRP2 LRP1B

1.96e-0985517GO:0038024
GeneOntologyMolecularFunctionlow-density lipoprotein particle receptor activity

VLDLR LRP1 LRP2 LRP1B

6.71e-0816514GO:0005041
GeneOntologyMolecularFunctionlipoprotein particle receptor activity

VLDLR LRP1 LRP2 LRP1B

2.19e-0721514GO:0030228
GeneOntologyMolecularFunctioncalcium ion binding

PRRG2 VLDLR COMP ENPP2 EDEM2 LRP1 LRP2 PLCB4 EFCAB7 LRP1B AGRN

2.32e-067495111GO:0005509
GeneOntologyMolecularFunctionproteoglycan binding

COMP FN1 LRP1 AGRN

8.63e-0651514GO:0043394
GeneOntologyMolecularFunctionsulfur compound binding

COMP FN1 CCN1 LRP1 ECI2 MSTN AGRN

1.71e-05323517GO:1901681
GeneOntologyMolecularFunctionscavenger receptor activity

SSC5D ENPP2 LRP1

4.40e-0527513GO:0005044
GeneOntologyMolecularFunctiongrowth factor binding

CCN1 NGFR LRP2 ACVR2A AGRN

4.80e-05156515GO:0019838
GeneOntologyMolecularFunctionheparan sulfate proteoglycan binding

COMP LRP1 AGRN

5.47e-0529513GO:0043395
GeneOntologyMolecularFunctionglycosaminoglycan binding

COMP FN1 CCN1 MSTN AGRN

5.95e-04268515GO:0005539
GeneOntologyMolecularFunctioncoreceptor activity

LRP1 NGFR ACVR2A

8.27e-0472513GO:0015026
GeneOntologyMolecularFunctionextracellular matrix binding

SSC5D CCN1 AGRN

8.61e-0473513GO:0050840
GeneOntologyMolecularFunctionamide binding

RANBP2 FOLR1 LRP1 NGFR ECI2

9.73e-04299515GO:0033218
GeneOntologyMolecularFunctionapolipoprotein binding

VLDLR LRP1

1.18e-0320512GO:0034185
GeneOntologyMolecularFunctionextracellular matrix structural constituent

COMP FN1 CCN1 AGRN

1.35e-03188514GO:0005201
GeneOntologyMolecularFunctionBMP binding

COMP AGRN

1.43e-0322512GO:0036122
GeneOntologyMolecularFunctionheparin binding

COMP FN1 CCN1 MSTN

1.45e-03192514GO:0008201
GeneOntologyMolecularFunctionhistone kinase activity

MST1 MST1L

2.32e-0328512GO:0035173
GeneOntologyMolecularFunctionubiquitin-like protein ligase activity

TRIM33 RANBP2 RNF7 TRIM69 TRIM6

3.40e-03398515GO:0061659
GeneOntologyMolecularFunctionlaminin binding

SSC5D AGRN

3.41e-0334512GO:0043236
GeneOntologyMolecularFunctionfibronectin binding

SSC5D COMP

4.24e-0338512GO:0001968
GeneOntologyMolecularFunctionlipoprotein particle receptor binding

LRP1 LRP2

4.46e-0339512GO:0070325
GeneOntologyMolecularFunctionprotein tyrosine kinase binding

MST1 MST1L TRIM6

6.53e-03149513GO:1990782
GeneOntologyMolecularFunctionmiRNA binding

ZC3H7B DND1

6.69e-0348512GO:0035198
GeneOntologyMolecularFunctionstructural molecule activity

KRT24 COMP FN1 CCN1 DSP SRBD1 AGRN

7.18e-03891517GO:0005198
GeneOntologyMolecularFunctioncytokine binding

IL22RA2 COMP AGRN

7.53e-03157513GO:0019955
GeneOntologyBiologicalProcesstransforming growth factor beta receptor superfamily signaling pathway

TRIM33 ZEB1 COMP CCN1 FOLR1 LRP1 LRP2 ACVR2A MSTN

1.27e-06445519GO:0141091
GeneOntologyBiologicalProcesscell surface receptor protein serine/threonine kinase signaling pathway

TRIM33 ZEB1 COMP CCN1 FOLR1 LRP1 LRP2 ACVR2A MSTN

2.45e-06482519GO:0007178
GeneOntologyBiologicalProcesschemotaxis

MST1 FN1 CCN1 ENPP2 LRP1 LRP2 MST1L MSTN AGRN

4.34e-06517519GO:0006935
GeneOntologyBiologicalProcesstaxis

MST1 FN1 CCN1 ENPP2 LRP1 LRP2 MST1L MSTN AGRN

4.48e-06519519GO:0042330
GeneOntologyBiologicalProcessartery development

COMP FOLR1 LRP1 NGFR LRP2

1.91e-05133515GO:0060840
GeneOntologyBiologicalProcessregulation of transmembrane receptor protein serine/threonine kinase signaling pathway

TRIM33 ZEB1 CCN1 FOLR1 LRP1 LRP2 ACVR2A

2.20e-05347517GO:0090092
GeneOntologyBiologicalProcesspositive regulation of cell projection organization

VLDLR FN1 ENPP2 LRP1 NGFR MSTN AGRN CPEB1

2.64e-05494518GO:0031346
GeneOntologyBiologicalProcesstranscytosis

LRP1 LRP2 TG

2.78e-0524513GO:0045056
GeneOntologyBiologicalProcesscellular response to growth factor stimulus

TRIM33 ZEB1 COMP CCN1 FOLR1 LRP1 NGFR LRP2 ACVR2A MSTN

3.68e-058505110GO:0071363
GeneOntologyBiologicalProcessresponse to growth factor

TRIM33 ZEB1 COMP CCN1 FOLR1 LRP1 NGFR LRP2 ACVR2A MSTN

5.08e-058835110GO:0070848
GeneOntologyBiologicalProcesspositive regulation of lysosomal protein catabolic process

LRP1 LRP2

5.97e-055512GO:1905167
GeneOntologyBiologicalProcesschemoattraction of axon

LRP1 LRP2

5.97e-055512GO:0061642
GeneOntologyBiologicalProcessregulation of cellular response to growth factor stimulus

TRIM33 ZEB1 CCN1 FOLR1 LRP1 NGFR LRP2

6.54e-05412517GO:0090287
GeneOntologyBiologicalProcessartery morphogenesis

COMP FOLR1 LRP1 LRP2

7.89e-0592514GO:0048844
GeneOntologyBiologicalProcessregulation of macrophage chemotaxis

MST1 MST1L MSTN

1.04e-0437513GO:0010758
GeneOntologyBiologicalProcessenzyme-linked receptor protein signaling pathway

TRIM33 ZEB1 COMP CCN1 FOLR1 LRP1 NGFR LRP2 ACVR2A MSTN AGRN

1.23e-0411865111GO:0007167
GeneOntologyBiologicalProcessBMP signaling pathway

TRIM33 COMP CCN1 LRP2 ACVR2A

1.24e-04197515GO:0030509
GeneOntologyBiologicalProcesspositive regulation of protein catabolic process in the vacuole

LRP1 LRP2

1.25e-047512GO:1904352
GeneOntologyBiologicalProcessregulation of nervous system development

FN1 ENPP2 LRP1 NGFR LRP2 SLITRK6 AGRN TG

1.37e-04625518GO:0051960
GeneOntologyBiologicalProcessregulation of phosphorylation

MST1 VLDLR RANBP2 IL22RA2 FN1 CCN1 ENPP2 ACVR2A TRIM6 MSTN AGRN

1.65e-0412265111GO:0042325
GeneOntologyBiologicalProcessresponse to BMP

TRIM33 COMP CCN1 LRP2 ACVR2A

1.87e-04215515GO:0071772
GeneOntologyBiologicalProcesscellular response to BMP stimulus

TRIM33 COMP CCN1 LRP2 ACVR2A

1.87e-04215515GO:0071773
GeneOntologyBiologicalProcessventricular compact myocardium morphogenesis

DSP LRP2

2.13e-049512GO:0003223
GeneOntologyBiologicalProcesspositive regulation of mammary gland epithelial cell proliferation

MST1 MST1L

2.13e-049512GO:0033601
GeneOntologyBiologicalProcessmammary duct terminal end bud growth

MST1 MST1L

2.13e-049512GO:0060763
GeneOntologyBiologicalProcessanimal organ morphogenesis

MST1 ZEB1 COMP CCN1 DSP FOLR1 NGFR LRP2 MST1L ACVR2A SLITRK6

2.23e-0412695111GO:0009887
GeneOntologyBiologicalProcessregulation of chemotaxis

MST1 FN1 MST1L MSTN AGRN

3.23e-04242515GO:0050920
GeneOntologyBiologicalProcessfolic acid transport

FOLR1 LRP2

3.25e-0411512GO:0015884
GeneOntologyBiologicalProcessregulation of locomotion

MST1 FN1 CCN1 ENPP2 LRP1 NGFR MST1L MSTN AGRN TMEFF2 CPEB1

3.28e-0413275111GO:0040012
GeneOntologyBiologicalProcessvitamin transport

FOLR1 LRP2 RTBDN

3.60e-0456513GO:0051180
GeneOntologyBiologicalProcessregulation of macrophage migration

MST1 MST1L MSTN

3.60e-0456513GO:1905521
GeneOntologyBiologicalProcessmacrophage chemotaxis

MST1 MST1L MSTN

3.60e-0456513GO:0048246
GeneOntologyBiologicalProcesstube morphogenesis

MST1 ZEB1 COMP FN1 CCN1 FOLR1 LRP1 NGFR LRP2 MST1L

3.69e-0411255110GO:0035239
GeneOntologyBiologicalProcessregulation of lysosomal protein catabolic process

LRP1 LRP2

3.89e-0412512GO:1905165
GeneOntologyBiologicalProcesstissue morphogenesis

MST1 CCN1 DSP FOLR1 NGFR LRP2 MST1L TMEFF2

4.69e-04750518GO:0048729
GeneOntologyBiologicalProcessregulation of protein catabolic process in the vacuole

LRP1 LRP2

5.35e-0414512GO:1904350
GeneOntologyBiologicalProcesspositive regulation of nervous system development

FN1 ENPP2 LRP1 LRP2 SLITRK6 AGRN

5.57e-04418516GO:0051962
GeneOntologyBiologicalProcessregulation of phosphate metabolic process

MST1 VLDLR RANBP2 IL22RA2 FN1 CCN1 ENPP2 ACVR2A TRIM6 MSTN AGRN

5.86e-0414215111GO:0019220
GeneOntologyBiologicalProcesstransforming growth factor beta receptor signaling pathway

TRIM33 ZEB1 FOLR1 LRP1 MSTN

5.88e-04276515GO:0007179
GeneOntologyBiologicalProcessregulation of phosphorus metabolic process

MST1 VLDLR RANBP2 IL22RA2 FN1 CCN1 ENPP2 ACVR2A TRIM6 MSTN AGRN

5.93e-0414235111GO:0051174
GeneOntologyBiologicalProcesspositive regulation of chemokine (C-X-C motif) ligand 2 production

CCN1 LRP1

6.17e-0415512GO:2000343
GeneOntologyBiologicalProcessregulation of cell migration

MST1 FN1 CCN1 ENPP2 LRP1 NGFR MST1L MSTN TMEFF2 CPEB1

6.59e-0412115110GO:0030334
GeneOntologyBiologicalProcesspositive regulation of protein metabolic process

VLDLR RNF7 CCN1 ENPP2 LRP1 NGFR LRP2 ACVR2A TRIM6 AGRN CPEB1

7.27e-0414585111GO:0051247
GeneOntologyBiologicalProcessepithelium development

MST1 ZEB1 KRT24 CCN1 DSP FOLR1 NGFR LRP2 MST1L SLITRK6 TMEFF2

7.74e-0414695111GO:0060429
GeneOntologyBiologicalProcessmorphogenesis of an epithelium

MST1 CCN1 FOLR1 NGFR LRP2 MST1L TMEFF2

7.80e-04619517GO:0002009
GeneOntologyBiologicalProcessplasma membrane bounded cell projection morphogenesis

VLDLR FN1 ENPP2 LRP1 NGFR LRP2 SLITRK6 AGRN

8.36e-04819518GO:0120039
GeneOntologyBiologicalProcesscell projection morphogenesis

VLDLR FN1 ENPP2 LRP1 NGFR LRP2 SLITRK6 AGRN

8.84e-04826518GO:0048858
GeneOntologyBiologicalProcessaxon development

FN1 FOLR1 LRP1 NGFR LRP2 SLITRK6 AGRN

9.65e-04642517GO:0061564
GeneOntologyBiologicalProcessregulation of cell junction assembly

VLDLR ENPP2 LRP1 SLITRK6 AGRN

9.76e-04309515GO:1901888
GeneOntologyBiologicalProcesscellular response to decreased oxygen levels

VLDLR ACVR2A MSTN CPEB1

9.77e-04178514GO:0036294
GeneOntologyBiologicalProcessmacrophage migration

MST1 MST1L MSTN

9.87e-0479513GO:1905517
GeneOntologyBiologicalProcessregulation of cell motility

MST1 FN1 CCN1 ENPP2 LRP1 NGFR MST1L MSTN TMEFF2 CPEB1

1.01e-0312805110GO:2000145
GeneOntologyBiologicalProcessaorta development

LRP1 NGFR LRP2

1.02e-0380513GO:0035904
GeneOntologyBiologicalProcessregulation of plasma membrane bounded cell projection organization

VLDLR FN1 ENPP2 LRP1 NGFR MSTN AGRN CPEB1

1.03e-03846518GO:0120035
GeneOntologyBiologicalProcessresponse to wounding

COMP FN1 CCN1 DSP FOLR1 LRP1 TMEFF2

1.12e-03659517GO:0009611
GeneOntologyBiologicalProcessregulation of cell projection organization

VLDLR FN1 ENPP2 LRP1 NGFR MSTN AGRN CPEB1

1.17e-03863518GO:0031344
GeneOntologyBiologicalProcessregulation of mammary gland epithelial cell proliferation

MST1 MST1L

1.22e-0321512GO:0033599
GeneOntologyBiologicalProcessregulation of transforming growth factor beta receptor signaling pathway

TRIM33 ZEB1 FOLR1 LRP1

1.29e-03192514GO:0017015
GeneOntologyBiologicalProcessregulation of phospholipase activity

CCN1 LRP1

1.34e-0322512GO:0010517
GeneOntologyBiologicalProcessregulation of cellular response to transforming growth factor beta stimulus

TRIM33 ZEB1 FOLR1 LRP1

1.37e-03195514GO:1903844
GeneOntologyBiologicalProcesscellular response to oxygen levels

VLDLR ACVR2A MSTN CPEB1

1.37e-03195514GO:0071453
GeneOntologyBiologicalProcesscellular response to transforming growth factor beta stimulus

TRIM33 ZEB1 FOLR1 LRP1 MSTN

1.42e-03336515GO:0071560
GeneOntologyBiologicalProcessreceptor-mediated endocytosis

VLDLR FOLR1 LRP1 LRP2 LRP1B

1.43e-03337515GO:0006898
GeneOntologyBiologicalProcessresponse to activity

ZEB1 FN1 MSTN

1.44e-0390513GO:0014823
GeneOntologyBiologicalProcessregulation of bone mineralization

COMP CCN1 ACVR2A

1.48e-0391513GO:0030500
GeneOntologyBiologicalProcessresponse to transforming growth factor beta

TRIM33 ZEB1 FOLR1 LRP1 MSTN

1.55e-03343515GO:0071559
GeneOntologyBiologicalProcesschordate embryonic development

GJB3 ZEB1 CCN1 FOLR1 LRP2 N4BP2L2 ACVR2A LRP1B

1.60e-03906518GO:0043009
GeneOntologyBiologicalProcesschemokine (C-X-C motif) ligand 2 production

CCN1 LRP1

1.60e-0324512GO:0072567
GeneOntologyBiologicalProcesslysosomal protein catabolic process

LRP1 LRP2

1.60e-0324512GO:1905146
GeneOntologyBiologicalProcessregulation of chemokine (C-X-C motif) ligand 2 production

CCN1 LRP1

1.60e-0324512GO:2000341
GeneOntologyBiologicalProcesspositive regulation of cellular component organization

VLDLR FN1 ENPP2 LRP1 NGFR LRP2 SLITRK6 MSTN AGRN CPEB1

1.65e-0313665110GO:0051130
GeneOntologyBiologicalProcessdevelopmental growth

MST1 COMP FN1 LRP1 MST1L SLITRK6 MSTN AGRN

1.65e-03911518GO:0048589
GeneOntologyBiologicalProcessregulation of protein phosphorylation

MST1 VLDLR IL22RA2 FN1 CCN1 ENPP2 ACVR2A TRIM6 AGRN

1.66e-031133519GO:0001932
GeneOntologyBiologicalProcessnegative regulation of apoptotic process

MST1 RNF7 COMP FN1 CCN1 LRP1 NGFR LRP2 MST1L

1.66e-031133519GO:0043066
GeneOntologyBiologicalProcessembryonic morphogenesis

ZEB1 FN1 CCN1 FOLR1 LRP2 ACVR2A SLITRK6

1.77e-03713517GO:0048598
GeneOntologyBiologicalProcesscardiac chamber development

CCN1 DSP LRP1 LRP2

1.86e-03212514GO:0003205
GeneOntologyBiologicalProcessembryo development ending in birth or egg hatching

GJB3 ZEB1 CCN1 FOLR1 LRP2 N4BP2L2 ACVR2A LRP1B

1.87e-03929518GO:0009792
GeneOntologyBiologicalProcesstube development

MST1 ZEB1 COMP FN1 CCN1 FOLR1 LRP1 NGFR LRP2 MST1L

2.01e-0314025110GO:0035295
GeneOntologyBiologicalProcesspeptide cross-linking

FN1 DSP

2.02e-0327512GO:0018149
GeneOntologyBiologicalProcessnegative regulation of programmed cell death

MST1 RNF7 COMP FN1 CCN1 LRP1 NGFR LRP2 MST1L

2.09e-031171519GO:0043069
GeneOntologyBiologicalProcessprotein catabolic process in the vacuole

LRP1 LRP2

2.17e-0328512GO:0007039
GeneOntologyBiologicalProcesslipoprotein transport

LRP1 LRP2

2.17e-0328512GO:0042953
GeneOntologyBiologicalProcesscell morphogenesis involved in neuron differentiation

VLDLR FN1 LRP1 NGFR LRP2 SLITRK6 AGRN

2.32e-03748517GO:0048667
GeneOntologyBiologicalProcessregulation of cellular component biogenesis

SPTBN5 VLDLR CCN1 ENPP2 LRP1 SLITRK6 MSTN AGRN TMEFF2

2.32e-031189519GO:0044087
GeneOntologyBiologicalProcesspositive regulation of cell population proliferation

MST1 COMP FN1 CCN1 ENPP2 NGFR LRP2 N4BP2L2 MST1L

2.33e-031190519GO:0008284
GeneOntologyBiologicalProcesslipoprotein localization

LRP1 LRP2

2.33e-0329512GO:0044872
GeneOntologyBiologicalProcessembryo development

GJB3 ZEB1 FN1 CCN1 FOLR1 LRP2 N4BP2L2 ACVR2A SLITRK6 LRP1B

2.40e-0314375110GO:0009790
GeneOntologyBiologicalProcesscell-substrate junction assembly

FN1 ENPP2 LRP1

2.42e-03108513GO:0007044
GeneOntologyCellularComponentcell surface

VLDLR FOLR1 CD163L1 LRP1 NGFR LRP2 CORIN ADAM29 RTBDN ACVR2A SLITRK6 AGRN KLRD1

1.81e-0611115113GO:0009986
GeneOntologyCellularComponentexternal side of plasma membrane

FOLR1 CD163L1 LRP1 NGFR LRP2 ADAM29 RTBDN KLRD1

3.41e-05519518GO:0009897
GeneOntologyCellularComponentaxonal growth cone

LRP1 LRP2 AGRN

1.81e-0445513GO:0044295
GeneOntologyCellularComponentside of membrane

FOLR1 CD163L1 LRP1 NGFR LRP2 ADAM29 RTBDN EFCAB7 KLRD1

2.37e-04875519GO:0098552
GeneOntologyCellularComponentcollagen-containing extracellular matrix

MST1 SSC5D COMP FN1 CCN1 RTBDN AGRN

2.85e-04530517GO:0062023
GeneOntologyCellularComponentgrowth cone

LRP1 NGFR LRP2 AGRN CPEB1

3.21e-04245515GO:0030426
GeneOntologyCellularComponentsite of polarized growth

LRP1 NGFR LRP2 AGRN CPEB1

3.72e-04253515GO:0030427
GeneOntologyCellularComponentdistal axon

PNMT LRP1 NGFR LRP2 AGRN CPEB1

6.40e-04435516GO:0150034
GeneOntologyCellularComponentclathrin-coated pit

VLDLR LRP1 LRP2

9.85e-0480513GO:0005905
GeneOntologyCellularComponentextracellular matrix

MST1 SSC5D COMP FN1 CCN1 RTBDN AGRN

1.01e-03656517GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

MST1 SSC5D COMP FN1 CCN1 RTBDN AGRN

1.03e-03658517GO:0030312
GeneOntologyCellularComponentclathrin-coated vesicle

FOLR1 LRP1 NGFR LRP2

2.65e-03237514GO:0030136
GeneOntologyCellularComponentreceptor complex

VLDLR LRP1 LRP2 ACVR2A LRP1B KLRD1

2.80e-03581516GO:0043235
GeneOntologyCellularComponentapical part of cell

SPTBN5 VLDLR FN1 FOLR1 LRP1 LRP2

3.07e-03592516GO:0045177
MousePhenoabnormal auditory brainstem response

SPTBN5 TRIM69 GJB3 ZEB1 NGFR LRP2 PLCB4 SLITRK6 EFCAB7 TG

1.39e-055764610MP:0004738
MousePhenoabnormal chorionic plate morphology

GJB3 CCN1 ENPP2

1.48e-0515463MP:0004560
MousePhenoabnormal hearing electrophysiology

SPTBN5 TRIM69 GJB3 ZEB1 NGFR LRP2 PLCB4 SLITRK6 EFCAB7 TG

1.82e-055944610MP:0006335
MousePhenoabnormal hearing physiology

SPTBN5 TRIM69 GJB3 ZEB1 NGFR LRP2 PLCB4 SLITRK6 EFCAB7 TG

3.59e-056434610MP:0001963
MousePhenoabnormal wound healing

GJB3 ZEB1 COMP FN1 NGFR ADAM29

3.79e-05193466MP:0005023
MousePhenoabnormal ear physiology

SPTBN5 TRIM69 GJB3 ZEB1 NGFR LRP2 PLCB4 SLITRK6 EFCAB7 TG

6.05e-056844610MP:0003878
MousePhenohearing/vestibular/ear phenotype

SPTBN5 TRIM69 GJB3 ZEB1 FOLR1 NGFR LRP2 PLCB4 SLITRK6 EFCAB7 TG

1.29e-049054611MP:0005377
DomainEGF_1

VLDLR COMP FN1 LRP1 LRP2 ADAM29 LRP1B AGRN TMEFF2

3.16e-08255529PS00022
DomainEGF-like_CS

VLDLR COMP FN1 LRP1 LRP2 ADAM29 LRP1B AGRN TMEFF2

3.86e-08261529IPR013032
DomainLdl_recept_b

VLDLR LRP1 LRP2 LRP1B

5.24e-0814524PF00058
DomainLDLRB

VLDLR LRP1 LRP2 LRP1B

5.24e-0814524PS51120
DomainLY

VLDLR LRP1 LRP2 LRP1B

7.13e-0815524SM00135
DomainLDLR_classB_rpt

VLDLR LRP1 LRP2 LRP1B

7.13e-0815524IPR000033
DomainLDLR_class-A_CS

VLDLR LRP1 LRP2 CORIN LRP1B

8.39e-0840525IPR023415
DomainLdl_recept_a

VLDLR LRP1 LRP2 CORIN LRP1B

1.54e-0745525PF00057
Domain-

VLDLR LRP1 LRP2 CORIN LRP1B

1.73e-07465254.10.400.10
DomainLDLRA_1

VLDLR LRP1 LRP2 CORIN LRP1B

2.15e-0748525PS01209
DomainLDLRA_2

VLDLR LRP1 LRP2 CORIN LRP1B

2.39e-0749525PS50068
DomainLDrepeatLR_classA_rpt

VLDLR LRP1 LRP2 CORIN LRP1B

2.39e-0749525IPR002172
DomainLDLa

VLDLR LRP1 LRP2 CORIN LRP1B

2.39e-0749525SM00192
DomainEGF_3

VLDLR COMP LRP1 LRP2 ADAM29 LRP1B AGRN TMEFF2

2.60e-07235528PS50026
DomainEGF-like_dom

VLDLR COMP LRP1 LRP2 ADAM29 LRP1B AGRN TMEFF2

4.05e-07249528IPR000742
DomainEGF_2

VLDLR COMP LRP1 LRP2 ADAM29 LRP1B AGRN TMEFF2

6.48e-07265528PS01186
DomainEGF_CA

VLDLR COMP LRP1 LRP2 LRP1B AGRN

1.09e-06122526SM00179
DomainEGF-like_Ca-bd_dom

VLDLR COMP LRP1 LRP2 LRP1B AGRN

1.20e-06124526IPR001881
DomainEGF

VLDLR LRP1 LRP2 LRP1B AGRN TMEFF2

1.32e-06126526PF00008
DomainEGF

VLDLR COMP LRP1 LRP2 LRP1B AGRN TMEFF2

3.77e-06235527SM00181
DomainEGF_CA

VLDLR COMP LRP1 LRP2 LRP1B

4.03e-0686525PF07645
Domain-

VLDLR LRP1 LRP2 LRP1B

4.09e-06395242.120.10.30
DomainGrowth_fac_rcpt_

VLDLR COMP CCN1 LRP1 LRP2 LRP1B

4.57e-06156526IPR009030
DomainEGF_Ca-bd_CS

VLDLR COMP LRP1 LRP2 LRP1B

7.30e-0697525IPR018097
DomainDUF5050

LRP1 LRP1B

7.60e-062522IPR032485
DomainDUF5050

LRP1 LRP1B

7.60e-062522PF16472
Domain6-blade_b-propeller_TolB-like

VLDLR LRP1 LRP2 LRP1B

7.99e-0646524IPR011042
DomainEGF_CA

VLDLR COMP LRP1 LRP2 LRP1B

8.06e-0699525PS01187
DomainSR

SSC5D CD163L1 CORIN

4.48e-0525523SM00202
DomainSRCR_1

SSC5D CD163L1 CORIN

5.06e-0526523PS00420
DomaincEGF

LRP1 LRP2 LRP1B

5.06e-0526523IPR026823
DomainSRCR_2

SSC5D CD163L1 CORIN

5.06e-0526523PS50287
DomaincEGF

LRP1 LRP2 LRP1B

5.06e-0526523PF12662
DomainSRCR-like_dom

SSC5D CD163L1 CORIN

5.06e-0526523IPR017448
DomainSRCR

SSC5D CD163L1 CORIN

5.68e-0527523IPR001190
DomainPAN_AP

MST1 MST1L

7.56e-055522SM00473
DomainFolate_rcpt

FOLR1 RTBDN

7.56e-055522IPR004269
DomainKringle-like

MST1 FN1 MST1L

9.54e-0532523IPR013806
DomainPAN

MST1 MST1L

1.58e-047522PS50948
DomainPan_app

MST1 MST1L

1.58e-047522IPR003609
DomainPAN_1

MST1 MST1L

1.58e-047522PF00024
DomainASX_HYDROXYL

VLDLR LRP1 LRP2 LRP1B

1.72e-04100524PS00010
DomainFolate_rcpt-like

FOLR1 RTBDN

2.11e-048522IPR018143
DomainFolate_rec

FOLR1 RTBDN

2.11e-048522PF03024
DomainEGF-type_Asp/Asn_hydroxyl_site

VLDLR LRP1 LRP2 LRP1B

2.15e-04106524IPR000152
DomainKringle

MST1 MST1L

1.01e-0317522IPR000001
DomainKringle_CS

MST1 MST1L

1.01e-0317522IPR018056
DomainKRINGLE_2

MST1 MST1L

1.01e-0317522PS50070
DomainKringle

MST1 MST1L

1.01e-0317522PF00051
DomainKRINGLE_1

MST1 MST1L

1.01e-0317522PS00021
DomainKR

MST1 MST1L

1.01e-0317522SM00130
Domain-

TRIM33 TRIM69 TRIM6

1.02e-03715234.10.45.10
DomainZnf_B-box

TRIM33 TRIM69 TRIM6

1.49e-0381523IPR000315
DomainSRCR

SSC5D CD163L1

1.54e-0321522PF00530
DomainKazal_1

AGRN TMEFF2

1.69e-0322522PF00050
Domain-

SSC5D CD163L1

2.19e-03255223.10.250.10
DomainSpectrin_repeat

SPTBN5 DSP

2.94e-0329522IPR002017
DomainConA-like_dom

TRIM69 COMP TRIM6 AGRN

3.21e-03219524IPR013320
DomainSpectrin/alpha-actinin

SPTBN5 DSP

3.57e-0332522IPR018159
DomainSPEC

SPTBN5 DSP

3.57e-0332522SM00150
DomainPeptidase_S1A

MST1 CORIN MST1L

3.84e-03113523IPR001314
DomainZnf-RING_LisH

TRIM33 TRIM6

4.03e-0334522IPR027370
Domainzf-RING_UBOX

TRIM33 TRIM6

4.03e-0334522PF13445
DomainTRYPSIN_DOM

MST1 CORIN MST1L

4.04e-03115523PS50240
DomainTryp_SPc

MST1 CORIN MST1L

4.24e-03117523SM00020
DomainKazal_2

AGRN TMEFF2

4.51e-0336522PF07648
DomainTrypsin

MST1 CORIN MST1L

4.65e-03121523PF00089
DomainTrypsin_dom

MST1 CORIN MST1L

4.65e-03121523IPR001254
DomainPeptidase_S1_PA

MST1 CORIN MST1L

4.87e-03123523IPR009003
PathwayWP_FATTY_ACIDS_AND_LIPOPROTEINS_TRANSPORT_IN_HEPATOCYTES

VLDLR SSC5D CD163L1 ENPP2 LRP1 LRP2 ECI2 LRP1B

1.40e-05381428M48063
PathwayWP_HYPERTROPHY_MODEL

ZEB1 CCN1 MSTN

2.31e-0519423MM15938
PathwayWP_HYPERTROPHY_MODEL

ZEB1 CCN1 MSTN

2.71e-0520423M39674
PathwayREACTOME_SIGNALING_BY_MST1

MST1 MST1L

1.29e-046422MM15492
PathwayBIOCARTA_MSP_PATHWAY

MST1 MST1L

1.80e-047422MM1580
PathwayWP_MIR302367_PROMOTING_CARDIOMYOCYTE_PROLIFERATION

MST1 MST1L

2.40e-048422MM15986
PathwayPID_UPA_UPAR_PATHWAY

VLDLR FN1 LRP1

2.60e-0442423M174
PathwayREACTOME_METABOLISM_OF_FAT_SOLUBLE_VITAMINS

LRP1 LRP2 AGRN

3.20e-0445423MM15344
PathwayREACTOME_ECM_PROTEOGLYCANS

COMP FN1 AGRN

3.64e-0447423MM14925
PathwayREACTOME_METABOLISM_OF_FAT_SOLUBLE_VITAMINS

LRP1 LRP2 AGRN

3.87e-0448423M27642
PathwayKEGG_MEDICUS_REFERENCE_TSH_DUOX2_TG_SIGNALING_PATHWAY

PLCB4 TG

5.61e-0412422M47628
PathwayWP_NEUROGENESIS_REGULATION_IN_THE_OLFACTORY_EPITHELIUM

VLDLR NGFR AGRN

6.43e-0457423M48326
PathwayWP_FAMILIAL_HYPERLIPIDEMIA_TYPE_3

VLDLR LRP1

6.62e-0413422M42551
Pubmed

LRP2 mediates folate uptake in the developing neural tube.

FOLR1 LRP1 LRP2 LRP1B

1.45e-091152424639464
Pubmed

Normal development and fertility of knockout mice lacking the tumor suppressor gene LRP1b suggest functional compensation by LRP1.

VLDLR LRP1 LRP2 LRP1B

4.40e-091452415082773
Pubmed

MESD is essential for apical localization of megalin/LRP2 in the visceral endoderm.

VLDLR LRP1 LRP2 LRP1B

2.61e-082152421337463
Pubmed

Interaction of coagulation factor VIII with members of the low-density lipoprotein receptor family follows common mechanism and involves consensus residues within the A2 binding site 484-509.

VLDLR LRP1 LRP2

3.15e-08552318685438
Pubmed

The PX-domain protein SNX17 interacts with members of the LDL receptor family and modulates endocytosis of the LDL receptor.

VLDLR LRP1 LRP2

1.10e-07752312169628
Pubmed

Stage-specific association of apolipoprotein A-I and E in developing mouse retina.

VLDLR LRP1 LRP2

1.13e-061452317389516
Pubmed

Cyr61, product of a growth factor-inducible immediate-early gene, regulates chondrogenesis in mouse limb bud mesenchymal cells.

FN1 CCN1

2.19e-0625229441684
Pubmed

Striking differences of LDL receptor-related protein 1B expression in mouse and human.

LRP1 LRP1B

2.19e-06252215963947
Pubmed

Endocytic Protein Defects in the Neural Crest Cell Lineage and Its Pathway Are Associated with Congenital Heart Defects.

LRP1 LRP2

2.19e-06252234445520
Pubmed

Mst1 regulates post-infarction cardiac injury through the JNK-Drp1-mitochondrial fission pathway.

MST1 MST1L

2.19e-06252229760744
Pubmed

Cloning, sequencing, and expression of human macrophage stimulating protein (MSP, MST1) confirms MSP as a member of the family of kringle proteins and locates the MSP gene on chromosome 3.

MST1 MST1L

2.19e-0625228393443
Pubmed

MSP is a negative regulator of inflammation and lipogenesis in ex vivo models of non-alcoholic steatohepatitis.

MST1 MST1L

2.19e-06252227609031
Pubmed

Hepatocyte growth factor-like protein is required for prostate tumor growth in the TRAMP mouse model.

MST1 MST1L

2.19e-06252224980820
Pubmed

Synergistically Acting on Myostatin and Agrin Pathways Increases Neuromuscular Junction Stability and Endurance in Old Mice.

MSTN AGRN

2.19e-06252237548943
Pubmed

Mst1 deletion reduces hyperglycemia-mediated vascular dysfunction via attenuating mitochondrial fission and modulating the JNK signaling pathway.

MST1 MST1L

2.19e-06252231206688
Pubmed

Synovial chondromatosis and soft tissue chondroma: extraosseous cartilaginous tumor defined by FN1 gene rearrangement.

FN1 ACVR2A

2.19e-06252231273315
Pubmed

The low density lipoprotein receptor-related protein mediates fibronectin catabolism and inhibits fibronectin accumulation on cell surfaces.

FN1 LRP1

2.19e-06252211867643
Pubmed

Matrix-matrix interaction of cartilage oligomeric matrix protein and fibronectin.

COMP FN1

2.19e-06252212225811
Pubmed

Structure of the human D1F15S1A locus: a chromosome 1 locus with 97% identity to the chromosome 3 gene coding for hepatocyte growth factor-like protein.

MST1 MST1L

2.19e-06252210728827
Pubmed

Genetically selected Marchigian Sardinian alcohol-preferring (msP) rats: an animal model to study the neurobiology of alcoholism.

MST1 MST1L

2.19e-06252216961763
Pubmed

Inhibiting endothelial cell Mst1 attenuates acute lung injury in mice.

MST1 MST1L

2.19e-06252239253972
Pubmed

Clearance of coagulation factor VIII in very low-density lipoprotein receptor knockout mice.

VLDLR LRP1

2.19e-06252215327526
Pubmed

LRP1 is required for novobiocin-mediated fibronectin turnover.

FN1 LRP1

2.19e-06252230061663
Pubmed

Cerebral ischemia-reperfusion is modulated by macrophage-stimulating 1 through the MAPK-ERK signaling pathway.

MST1 MST1L

2.19e-06252232017081
Pubmed

Mst1 inhibition attenuates non-alcoholic fatty liver disease via reversing Parkin-related mitophagy.

MST1 MST1L

2.19e-06252230708325
Pubmed

Functional consequences of the macrophage stimulating protein 689C inflammatory bowel disease risk allele.

MST1 MST1L

2.19e-06252224409221
Pubmed

Melatonin alleviates postinfarction cardiac remodeling and dysfunction by inhibiting Mst1.

MST1 MST1L

2.19e-06252227696525
Pubmed

Megalin (gp330): a putative endocytic receptor for thyroglobulin (Tg).

LRP2 TG

2.19e-0625229492085
Pubmed

Hepatocyte-specific expression of the mouse hepatocyte growth factor-like protein.

MST1 MST1L

2.19e-0625228340069
Pubmed

Biological effects of targeted inactivation of hepatocyte growth factor-like protein in mice.

MST1 MST1L

2.19e-0625229486989
Pubmed

Treatment with XMU-MP-1 erases hyperglycaemic memory in hearts of diabetic mice.

MST1 MST1L

2.19e-06252233887258
Pubmed

HGFL supports mammary tumorigenesis by enhancing tumor cell intrinsic survival and influencing macrophage and T-cell responses.

MST1 MST1L

2.19e-06252225938541
Pubmed

Interactions of the low density lipoprotein receptor gene family with cytosolic adaptor and scaffold proteins suggest diverse biological functions in cellular communication and signal transduction.

VLDLR LRP1 LRP2

2.53e-061852310827173
Pubmed

The binding sites for the very low density lipoprotein receptor and low-density lipoprotein receptor-related protein are shared within coagulation factor VIII.

VLDLR LRP1

6.57e-06352218277139
Pubmed

The Ron/STK receptor tyrosine kinase is essential for peri-implantation development in the mouse.

MST1 MST1L

6.57e-06352210225971
Pubmed

Inhibition of MST1 ameliorates neuronal apoptosis via GSK3β/β-TrCP/NRF2 pathway in spinal cord injury accompanied by diabetes.

MST1 MST1L

6.57e-06352238430683
Pubmed

Macrophage stimulating protein is a target-derived neurotrophic factor for developing sensory and sympathetic neurons.

MST1 MST1L

6.57e-06352212538524
Pubmed

Mst1 controls lymphocyte trafficking and interstitial motility within lymph nodes.

MST1 MST1L

6.57e-06352219339990
Pubmed

TRAF2 functions as an activator switch in the reactive oxygen species-induced stimulation of MST1.

MST1 MST1L

6.57e-06352226698664
Pubmed

Melatonin activates Parkin translocation and rescues the impaired mitophagy activity of diabetic cardiomyopathy through Mst1 inhibition.

MST1 MST1L

6.57e-06352230063115
Pubmed

Mst1-mediated phosphorylation of Bcl-xL is required for myocardial reperfusion injury.

MST1 MST1L

6.57e-06352227218122
Pubmed

Inhibition of endogenous Mst1 prevents apoptosis and cardiac dysfunction without affecting cardiac hypertrophy after myocardial infarction.

MST1 MST1L

6.57e-06352217395874
Pubmed

Genetic deletion of Mst1 alters T cell function and protects against autoimmunity.

MST1 MST1L

6.57e-06352224852423
Pubmed

Regulation of muscle growth by multiple ligands signaling through activin type II receptors.

ACVR2A MSTN

6.57e-06352216330774
Pubmed

The hepatic uptake of VLDL in lrp-ldlr-/-vldlr-/- mice is regulated by LPL activity and involves proteoglycans and SR-BI.

VLDLR LRP1

6.57e-06352218367731
Pubmed

Mst1 participates in the atherosclerosis progression through macrophage autophagy inhibition and macrophage apoptosis enhancement.

MST1 MST1L

6.57e-06352227496379
Pubmed

Macrophage-stimulating protein cooperates with erythropoietin to induce colony formation and MAP kinase activation in primary erythroid progenitor cells.

MST1 MST1L

6.57e-06352212804176
Pubmed

Receptor tyrosine kinase Ron is expressed in mouse reproductive tissues during embryo implantation and is important in trophoblast cell function.

MST1 MST1L

6.57e-06352212606483
Pubmed

The relationship among apolipoprotein(a) polymorphisms, the low-density lipoprotein receptor-related protein, and the very low density lipoprotein receptor genes, and plasma lipoprotein(A) concentration in the Czech population.

VLDLR LRP1

6.57e-06352211931574
Pubmed

Mst1-mediated phosphorylation of Nur77 improves the endometrial receptivity in human and mice.

MST1 MST1L

6.57e-06352236623453
Pubmed

Hippo Kinase MST1-Mediated Cell Metabolism Reprograms the Homeostasis and Differentiation of Granulocyte Progenitor Cells.

MST1 MST1L

6.57e-06352237184367
Pubmed

CircRbms1 fosters MST1 mRNA and protein levels to motivate myocardial ischaemia-reperfusion injury via autophagic status.

MST1 MST1L

6.57e-06352238288506
Pubmed

The proto-oncogene RON is involved in development of epithelial, bone and neuro-endocrine tissues.

MST1 MST1L

6.57e-0635228545120
Pubmed

Hepatocyte growth factor-like protein is a positive regulator of early mammary gland ductal morphogenesis.

MST1 MST1L

6.57e-06352225049204
Pubmed

Lubricin binds cartilage proteins, cartilage oligomeric matrix protein, fibronectin and collagen II at the cartilage surface.

COMP FN1

6.57e-06352229030641
Pubmed

Characterization of the mouse cDNA and gene coding for a hepatocyte growth factor-like protein: expression during development.

MST1 MST1L

6.57e-0635221832957
Pubmed

Activation of pro-survival CaMK4β/CREB and pro-death MST1 signaling at early and late times during a mouse model of prion disease.

MST1 MST1L

6.57e-06352225183307
Pubmed

MST1 mediates neuronal loss and cognitive deficits: A novel therapeutic target for Alzheimer's disease.

MST1 MST1L

6.57e-06352235525373
Pubmed

MST1 coordinately regulates autophagy and apoptosis in diabetic cardiomyopathy in mice.

MST1 MST1L

6.57e-06352227510910
Pubmed

Combination of melatonin and irisin ameliorates lipopolysaccharide-induced cardiac dysfunction through suppressing the Mst1-JNK pathways.

MST1 MST1L

6.57e-06352231976559
Pubmed

Over-expressed MST1 impaired spatial memory via disturbing neural oscillation patterns in mice.

MST1 MST1L

6.57e-06352232468668
Pubmed

Nicorandil alleviates myocardial injury and post-infarction cardiac remodeling by inhibiting Mst1.

MST1 MST1L

6.57e-06352229127009
Pubmed

Mst1 Kinase Regulates the Actin-Bundling Protein L-Plastin To Promote T Cell Migration.

MST1 MST1L

6.57e-06352227465533
Pubmed

Suramin protects hepatocytes from LPS-induced apoptosis by regulating mitochondrial stress and inactivating the JNK-Mst1 signaling pathway.

MST1 MST1L

6.57e-06352230771091
Pubmed

MST1 mediates the N-methyl-D-aspartate-induced excitotoxicity in mouse cortical neurons.

MST1 MST1L

6.57e-06352234967918
Pubmed

Hippo kinases Mst1 and Mst2 maintain NK cell homeostasis by orchestrating metabolic state and transcriptional activity.

MST1 MST1L

6.57e-06352238898027
Pubmed

WASP and Mst1 coregulate B-cell development and B-cell receptor signaling.

MST1 MST1L

6.57e-06352232045478
Pubmed

Impaired liver regeneration in aged mice can be rescued by silencing Hippo core kinases MST1 and MST2.

MST1 MST1L

6.57e-06352227940445
Pubmed

Inhibition of TLR4-induced IκB kinase activity by the RON receptor tyrosine kinase and its ligand, macrophage-stimulating protein.

MST1 MST1L

1.31e-05452221078906
Pubmed

MST1 controls murine neutrophil homeostasis via the G-CSFR/STAT3 axis.

MST1 MST1L

1.31e-05452236618429
Pubmed

Hyperglycemia-Induced Overexpression of PH Domain Leucine-Rich Repeat Protein Phosphatase 1 (PHLPP1) Compromises the Cardioprotective Effect of Ischemic Postconditioning Via Modulation of the Akt/Mst1 Pathway Signaling.

MST1 MST1L

1.31e-05452235715527
Pubmed

Disabled-2 is essential for endodermal cell positioning and structure formation during mouse embryogenesis.

LRP1 LRP2

1.31e-05452212413896
Pubmed

Rab13 acts downstream of the kinase Mst1 to deliver the integrin LFA-1 to the cell surface for lymphocyte trafficking.

MST1 MST1L

1.31e-05452225074980
Pubmed

OSM mitigates post-infarction cardiac remodeling and dysfunction by up-regulating autophagy through Mst1 suppression.

MST1 MST1L

1.31e-05452227825852
Pubmed

MST1 deficiency promotes B cell responses by CD4+ T cell-derived IL-4, resulting in hypergammaglobulinemia.

MST1 MST1L

1.31e-05452228527887
Pubmed

Mst1 directs Myosin IIa partitioning of low and higher affinity integrins during T cell migration.

MST1 MST1L

1.31e-05452225133611
Pubmed

LncRNA SNHG17 knockdown promotes Parkin-dependent mitophagy and reduces apoptosis of podocytes through Mst1.

MST1 MST1L

1.31e-05452232627655
Pubmed

Macrophage MST1/2 Disruption Impairs Post-Infarction Cardiac Repair via LTB4.

MST1 MST1L

1.31e-05452234515499
Pubmed

The Mst1 and Mst2 kinases control activation of rho family GTPases and thymic egress of mature thymocytes.

MST1 MST1L

1.31e-05452222412158
Pubmed

Functional role of Mst1/Mst2 in embryonic stem cell differentiation.

MST1 MST1L

1.31e-05452224224013
Pubmed

Mst1 regulates hepatic lipid metabolism by inhibiting Sirt1 ubiquitination in mice.

MST1 MST1L

1.31e-05452226903296
Pubmed

Regulation of myostatin activity and muscle growth.

ACVR2A MSTN

1.31e-05452211459935
Pubmed

Glyceraldehyde-3-phosphate dehydrogenase interacts with proapoptotic kinase mst1 to promote cardiomyocyte apoptosis.

MST1 MST1L

1.31e-05452223527007
Pubmed

A cell-intrinsic role for Mst1 in regulating thymocyte egress.

MST1 MST1L

1.31e-05452219692642
Pubmed

Identification of the low density lipoprotein receptor-related protein (LRP) as an endocytic receptor for thrombospondin-1.

LRP1 LRP2

1.31e-0545227775583
Pubmed

Nerve growth factor receptor increases the tumor growth and metastatic potential of triple-negative breast cancer cells.

ZEB1 NGFR

1.31e-05452233627781
Pubmed

Melatonin protects against diabetic cardiomyopathy through Mst1/Sirt3 signaling.

MST1 MST1L

1.31e-05452228480597
Pubmed

Spatiotemporal regulation of the kinase Mst1 by binding protein RAPL is critical for lymphocyte polarity and adhesion.

MST1 MST1L

1.31e-05452216892067
Pubmed

Role of apolipoprotein E receptors in regulating the differential in vivo neurotrophic effects of apolipoprotein E.

LRP1 LRP2

1.31e-05452211421580
Pubmed

Hippo signaling pathway reveals a spatio-temporal correlation with the size of primordial follicle pool in mice.

MST1 MST1L

1.31e-05452225659841
Pubmed

The apoE isoform binding properties of the VLDL receptor reveal marked differences from LRP and the LDL receptor.

VLDLR LRP1

1.31e-05452215863833
Pubmed

Mammalian Sterile 20-like Kinase 1 (Mst1) Enhances the Stability of Forkhead Box P3 (Foxp3) and the Function of Regulatory T Cells by Modulating Foxp3 Acetylation.

MST1 MST1L

1.31e-05452226538561
Pubmed

MST1 functions as a key modulator of neurodegeneration in a mouse model of ALS.

MST1 MST1L

1.31e-05452223818595
Pubmed

RON (MST1R) and HGFL (MST1) Co-Overexpression Supports Breast Tumorigenesis through Autocrine and Paracrine Cellular Crosstalk.

MST1 MST1L

1.31e-05452235626096
Pubmed

Mammalian sterile 20-like kinase 1 suppresses lymphoma development by promoting faithful chromosome segregation.

MST1 MST1L

1.31e-05452222926556
Pubmed

Treatment with Mammalian Ste-20-like Kinase 1/2 (MST1/2) Inhibitor XMU-MP-1 Improves Glucose Tolerance in Streptozotocin-Induced Diabetes Mice.

MST1 MST1L

1.31e-05452232987643
Pubmed

Myostatin, follistatin and activin type II receptors are highly expressed in adenomyosis.

ACVR2A MSTN

1.31e-05452226086422
Pubmed

The Mst1 Kinase Is Required for Follicular B Cell Homing and B-1 B Cell Development.

MST1 MST1L

1.31e-05452230386341
Pubmed

A combination of SILAC and nucleotide acyl phosphate labelling reveals unexpected targets of the Rsk inhibitor BI-D1870.

MST1 MST1L

1.31e-05452227919044
Pubmed

Mst1/2 Kinases Modulate Glucose Uptake for Osteoblast Differentiation and Bone Formation.

MST1 MST1L

1.31e-05452229474739
InteractionSCGB1A1 interactions

FN1 LRP2 AGRN

3.51e-0612523int:SCGB1A1
InteractionZFP41 interactions

LRP1 LRP2 LRP1B AGRN

1.41e-0557524int:ZFP41
InteractionANKRD36B interactions

VLDLR LRP1 LRP2 LRP1B

1.73e-0560524int:ANKRD36B
InteractionCHFR interactions

RANBP2 RNF7 ZEB1 LRP1

1.73e-0560524int:CHFR
InteractionIGFL3 interactions

VLDLR LRP2 LRP1B AGRN

4.18e-0575524int:IGFL3
InteractionLRPAP1 interactions

VLDLR RANBP2 LRP1 LRP2 LRP1B

9.95e-05180525int:LRPAP1
InteractionLPL interactions

VLDLR LRP1 LRP2

1.00e-0435523int:LPL
InteractionFGA interactions

TRIM33 FN1 TRIM6 LRP1B

1.05e-0495524int:FGA
GeneFamilyLow density lipoprotein receptors

VLDLR LRP1 LRP2 LRP1B

5.71e-0913324634
GeneFamilyRing finger proteins|Tripartite motif containing|ARF GTPase family

TRIM33 TRIM69 TRIM6

6.24e-049532359
GeneFamilyC2-set domain containing|Immunoglobulin like domain containing|Scavenger receptors

SSC5D CD163L1

1.04e-03273221253
GeneFamilyRing finger proteins

TRIM33 RNF7 TRIM69 TRIM6

1.35e-0327532458
CoexpressionAtlaskidney_e15.5_Podocyte_MafB_k-means-cluster#4_top-relative-expression-ranked_1000

VLDLR DSP FOLR1 ENPP2 LRP2 CORIN ECI2 SLITRK6

3.20e-07274528gudmap_kidney_e15.5_Podocyte_MafB_k4_1000
CoexpressionAtlaskidney_P4_CapMesRenVes_Crym_k-means-cluster#3_top-relative-expression-ranked_1000

VLDLR DSP ENPP2 LRP2 CORIN

3.07e-05148525gudmap_kidney_P4_CapMesRenVes_Crym_k3_1000
CoexpressionAtlaskidney_e15.5_Podocyte_MafB_k-means-cluster#1_top-relative-expression-ranked_500

VLDLR ENPP2 LRP2 CORIN ECI2

5.31e-05166525gudmap_kidney_e15.5_Podocyte_MafB_k1_500
CoexpressionAtlasStromal Cells, FRC.MLN, gp38+ CD31- CD140a+, Lymph Node, avg-5

FN1 CCN1 ENPP2 LRP1

6.12e-0587524GSM777050_100
CoexpressionAtlasStromal Cells, Fi.Sk, gp38+ CD140a+, Skin, avg-4

FN1 CCN1 ENPP2 LRP1

9.36e-0597524GSM777046_100
CoexpressionAtlaskidney_e15.5_Podocyte_MafB_top-relative-expression-ranked_1000

VLDLR DSP FOLR1 ENPP2 LRP2 CORIN ECI2 SLITRK6 EFCAB7

1.43e-04814529gudmap_kidney_e15.5_Podocyte_MafB_1000
ToppCellParenchymal-10x3prime_v2-Stromal-Fibroblastic-Fibro_myofibroblast|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

SSC5D COMP FN1 CCN1 ENPP2 LRP1 SLITRK6

3.49e-09200527251fd2923f108cd2086961d897244b392c32ad54
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

SSC5D ZEB1 ENPP2 NGFR PLCB4 SLITRK6

7.75e-081855269f19f04fc4d97dfc2dd78cde77b515f1cb5d51ec
ToppCelldroplet-Limb_Muscle-nan-18m-Mesenchymal-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VLDLR SSC5D IL22RA2 FN1 ENPP2 LRP1

9.66e-081925262d9e2262f1342fe17735f21f733c029d1275e955
ToppCell(5)_Fibroblasts-(5)_Fibroblast-B_(Myofibroblast)|(5)_Fibroblasts / Lung cell shreds - cell class (v4) and cell subclass (v4)

SSC5D COMP FN1 ENPP2 CORIN SLITRK6

1.16e-07198526196257c4420ac801ed9fbb444f11718adb7560ae
ToppCell3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-Pericytes-angiogenic_pericyte|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CCN1 CD163L1 EDEM2 PLCB4 TMEFF2

1.73e-06172525107417cfab7775bc1f80807115047abfb50b7a7e
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SSC5D FN1 LRP1 NGFR MSTN

1.88e-0617552512f5fd83c7710fc0c77406f765d9cbd133433b8b
ToppCell5'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DSP ADAM29 RTBDN LRP1B TMEFF2

2.16e-061805256b1606238417490e0d9930870a7827419d1c3737
ToppCellfacs-Mammary_Gland-Mammary_Gland-3m-Mesenchymal-stromal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SSC5D ZEB1 FN1 ENPP2 TMEFF2

2.47e-061855253cd0686a14e734a0f243070ab939adcb4c454478
ToppCellfacs-Mammary_Gland-Mammary_Gland-3m-Mesenchymal-stromal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SSC5D ZEB1 FN1 ENPP2 TMEFF2

2.47e-0618552500258f458cbf6d36449db95528a6b5038d731d2d
ToppCellfacs-Mammary_Gland-Mammary_Gland-3m-Mesenchymal|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SSC5D ZEB1 FN1 ENPP2 TMEFF2

2.47e-06185525a94694e226856bc5b168464f52d76004145717a5
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

SSC5D ZEB1 FN1 NGFR SLITRK6

2.47e-061855251ac6a32cc56d5d819649bdd99518e2ead0eead4c
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

SSC5D ZEB1 FN1 NGFR SLITRK6

2.54e-061865257def03dd856b765bd3f493288641981c4f7fd26e
ToppCellFetal_29-31_weeks-Mesenchymal-myofibroblast_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SSC5D ZEB1 FN1 ENPP2 SLITRK6

2.61e-06187525c104fbfef2d0bef64077ac721edf2379fd59d547
ToppCellfacs-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l20-1|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SSC5D ZEB1 FN1 ENPP2 TMEFF2

2.68e-06188525aa516273cdde53c8c0295f06830972388f890c97
ToppCellMesenchymal-myofibroblast_cell|World / Lineage, Cell type, age group and donor

SSC5D ZEB1 FN1 ENPP2 SLITRK6

2.75e-0618952544e37f88137bb249933eb615235b2cf2ae7f3925
ToppCell(2)_Fibroblasts-(22)_Fibro-3|World / Cell class and subclass of bone marrow stroma cells in homeostatis

SSC5D FOLR1 ENPP2 MSTN TMEFF2

2.82e-061905253aed03b87ba2c8d479048c3ceef3ff5e38746c28
ToppCelldroplet-Fat-Gat-18m-Mesenchymal-Cd34+|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VLDLR ENPP2 LRP1 NGFR TMEFF2

2.89e-061915256cab0334f76c973880bd8d1638856f2f6e4a249a
ToppCelldroplet-Fat-Gat-18m-Mesenchymal|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VLDLR ENPP2 LRP1 NGFR TMEFF2

2.89e-06191525850c6fff6dc795431ef534fdaa41e4ad50f7367a
ToppCelldroplet-Mammary_Gland-nan-18m-Mesenchymal-stromal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FN1 CCN1 ENPP2 LRP1 TMEFF2

2.89e-06191525a57cf0519d749febc0b69fe0b098b7ba53d63258
ToppCelldroplet-Fat-Gat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VLDLR ENPP2 LRP1 NGFR TMEFF2

2.89e-061915258b2b00202d3c98bccbae1b4a23713892fad0ff23
ToppCelldroplet-Mammary_Gland-nan-18m-Mesenchymal|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FN1 CCN1 ENPP2 LRP1 TMEFF2

2.89e-0619152519c67a812b8ce97472d316acd15aeefe8736000d
ToppCelldroplet-Limb_Muscle-Pre-Sort-18m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SSC5D COMP FN1 LRP1 TMEFF2

2.89e-061915251b26056df078674f37a6c06f6256b30cfcec21a7
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_119|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COMP FN1 CCN1 LRP1 NGFR

2.97e-06192525f88aba74d6e8c594c32fe2bc095b5da28b4b28e9
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast-Degenerative_Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COMP FN1 CCN1 LRP1 NGFR

2.97e-0619252541a8326cd5bc19ad5041068501bab4c72399222e
ToppCellLA|World / Chamber and Cluster_Paper

ZEB1 FN1 LRP1 LRP2 LRP1B

3.04e-06193525d4bf89437216baf489ea0239136dcedf3b6714af
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COMP FN1 CCN1 LRP1 NGFR

3.20e-0619552547762d9e442fb1f6f0033e3e10f4c6e498d2c081
ToppCellwk_20-22-Mesenchymal-Fibroblast-Airway_fibro|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

VLDLR FN1 CCN1 NGFR SLITRK6

3.36e-06197525233caeee200ca905900226f85426e084caf290fb
ToppCell3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VLDLR SSC5D NGFR PLCB4 ACVR2A

3.36e-061975256b6440f1baad5680cf9e13ca3ab72a2c65523d59
ToppCellTracheal-10x5prime-Stromal-Chondrocytic|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

COMP FN1 LRP1 CORIN LRP1B

3.45e-06198525c72ef2ddcbb6dacbed4c6200d89e17d57314dcdc
ToppCellTracheal-10x5prime-Stromal-Chondrocytic-Chondrocyte|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

COMP FN1 LRP1 CORIN LRP1B

3.45e-0619852555f013e9e6587d9ece59751fa131b1d22d6cceea
ToppCellFibroblasts-CD34+_Fibroblasts|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

SSC5D COMP FN1 CCN1 LRP1

3.53e-0619952513ff7409e200a0b46cdb7924d15ef33639693622
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_perichondrial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ZEB1 COMP FN1 CCN1 LRP1

3.62e-06200525a4ec0e80f5422b91b85264a9bb74568dd577e285
ToppCellTracheal-10x5prime-Stromal-Fibroblastic-Fibro_peribronchial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ZEB1 COMP FN1 LRP1 CORIN

3.62e-062005258ab0051544ea32eb8b3f7f8ba7582deaf8bf26c0
ToppCellBrain_organoid-organoid_Tanaka_cellReport-3m-Mesenchymal-BMP_responsible_cell|3m / Sample Type, Dataset, Time_group, and Cell type.

LRRIQ1 CCN1 DSP FOLR1 ENPP2

3.62e-06200525a4b52466b6426a835655b5fe7487e15aea816e14
ToppCelldistal-Epithelial-Basal|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

GJB3 DSP FOLR1 NGFR SLITRK6

3.62e-062005255c14f0c09bb8b3daf6d649032e888a7880c52b73
ToppCellParenchymal-10x3prime_v2-Stromal-Fibroblastic-Fibro_peribronchial|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

COMP FN1 CCN1 LRP1 CORIN

3.62e-06200525efdf7066b7dd43e35dbc0d2719b75f250cf54af2
ToppCellBronchial-10x5prime-Epithelial-Epi_airway_basal-Basal|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

GJB3 CCN1 DSP NGFR SLITRK6

3.62e-062005250594ca7bc313b73e1dc800cf058f8f798b0284cb
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c06-TNF|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ZC3H7B DND1 KLRD1 TG

2.29e-0514252461eefa32926a057e53747633bf4a81f09ea721c5
ToppCellAdult-Epithelial-basal_cell-D122|Adult / Lineage, Cell type, age group and donor

GJB3 NGFR SLITRK6 MSTN

3.14e-0515452438d346402417960044ae999e61f0092b46f2b591
ToppCellfacs-Marrow-Granulocytes-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRIM69 FN1 LRP1 AGRN

3.65e-0516052456e6f4b82b5dc41c45f9d253c2db314a6f702b84
ToppCellfacs-Marrow-Granulocytes-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRIM69 FN1 LRP1 AGRN

3.65e-05160524bb1b966fb9e801db15e67d03e49db4609d6f935a
ToppCellfacs-Marrow-Granulocytes-18m-Hematologic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRIM69 FN1 LRP1 AGRN

3.74e-0516152460f433eab9d5531bdf6aa86b0265f20b866b904c
ToppCellCD8+_Memory_T_cell-FLU-1|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

VLDLR ZDHHC23 NGFR ECI2

3.83e-0516252476f39935763848ea6e7917b2f9f1432c543063d9
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-Mes-like|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MST1 LRP1 LRP1B TMEFF2

3.93e-05163524360cd65decda24853124f33a174f5224d7f3ce23
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-Mes-like-AT1_Progenitor|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MST1 LRP1 LRP1B TMEFF2

3.93e-05163524b59d9b4f7c9f4e5e2c7783a49a96729dae3a81e5
ToppCellwk_08-11-Mesenchymal-Fibroblast-Alveolar_fibro|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

FN1 ENPP2 LRP1 MSTN

4.21e-0516652465dafed953b01a9830b54309af75c7a561e88336
ToppCellfacs-Trachea-nan-18m-Mesenchymal-chondrocyte|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COMP FN1 CCN1 RTBDN

4.31e-051675247b1fd19946cee67dae68f0f0d98420abcd532482
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m-Mesenchymal|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SSC5D FN1 LRP1 TMEFF2

4.52e-05169524bb43abad2c049b7f4d307737347290e01b3339a3
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Hematologic-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLCB4 ACVR2A TRIM6 DND1

4.52e-051695244e1322cc5e1733e9fb19e08f739a30206f43cea8
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m-Mesenchymal-stromal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SSC5D FN1 LRP1 TMEFF2

4.52e-051695245f18e3f40a5b1b167903f37516ec8181e889c7c5
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m-Mesenchymal-stromal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SSC5D FN1 LRP1 TMEFF2

4.52e-051695248bfa2d3bb541d02f55d7c95b8fd156c8403befca
ToppCellnormal-na-Lymphocytic_NK-natural_killer_cell-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

SPTBN5 VLDLR KLRD1 CPEB1

4.73e-05171524d339840626211a7bf1a9eb8f14d6c9509ab05e1c
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_artery-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

ZEB1 PNMT ENPP2 PLCB4

4.73e-051715241597459c971d6befa991d59dc66b41b6a522f797
ToppCell10x5'-bone_marrow-Myeloid_Mac-Intestinal_macrophages|bone_marrow / Manually curated celltypes from each tissue

SPTBN5 SSC5D ENPP2 LRP1

5.06e-051745240746344d62aa7ab77c378e9d5a9f9238e741a76b
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

COMP FN1 LRP1 CORIN

5.29e-051765249bc87cd5cda2372e1bce94c9dfd408eb1dfd8d0c
ToppCell343B-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)-|343B / Donor, Lineage, Cell class and subclass (all cells)

FN1 CCN1 LRP1 LRP1B

5.29e-051765242e94bbe17c0bb65dc58b4ebc0cb829258bd7373b
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

COMP FN1 LRP1 CORIN

5.29e-051765243f8274a7ab67f9f8a8923193763a5543cfe4defa
ToppCellP03-Epithelial-airway_epithelial_cell-ciliated_cell_of_airway|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

FN1 CCN1 DSP AGRN

5.29e-05176524f3a54038cde58326f1caed96ecca33c141bcc8b3
ToppCell343B-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)|343B / Donor, Lineage, Cell class and subclass (all cells)

FN1 CCN1 LRP1 LRP1B

5.29e-05176524f33ab41d121b59d871ad7d48ca021524a027d2ef
ToppCell10x3'2.3-week_12-13-Mesenchymal_osteo-stroma-early_osteoblast|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

FN1 CCN1 FOLR1 ENPP2

5.53e-05178524e32f5ed7a492edfa7073416008b1fcfae6b854ad
ToppCell(3)_Chondrocytes-(32)_Chondro-prehyper-2|(3)_Chondrocytes / Cell class and subclass of bone marrow stroma cells in homeostatis

VLDLR ENPP2 CORIN SRBD1

5.77e-05180524708a5c89b9337e281fce4f482892a1c1766c7812
ToppCellfacs-Pancreas-Exocrine-24m|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COMP FN1 LRP2 LRP1B

5.77e-0518052472310baeed848f2c483ae986cd73d2fb2cca7feb
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SSC5D LRP1 NGFR MSTN

5.90e-05181524a2058d658f07ab6f0a28d2622f3090b4cde6f763
ToppCellfacs-GAT-Fat-3m-Epithelial-epithelial_cell|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GJB3 LRRIQ1 FOLR1 LRP2

5.90e-05181524e97cbaafb93fdbee8e3cf4a06e6bcf121d941403
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SSC5D COMP FN1 CCN1

5.90e-051815249c157de9d3403e092c907599f2a2c16db5b21131
ToppCellFetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SSC5D ZEB1 COMP FN1

5.90e-05181524d7e04e0ca549eac6d9b1192b6578f9b54943d54f
ToppCellfacs-GAT-Fat-3m-Epithelial|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GJB3 LRRIQ1 FOLR1 LRP2

5.90e-0518152411cb84528f7ca084f0a92eda4f2e18e63a428fe9
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SSC5D COMP FN1 MSTN

5.90e-05181524b116c68393d8836bac080f81a8fcbeb52e0403e7
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SSC5D LRP1 NGFR MSTN

5.90e-05181524526e858a848470b6d2d5248788004d9735ed3add
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SSC5D COMP FN1 CCN1

5.90e-05181524eea943fdcbef0bbaa8578f3296923e874893b405
ToppCellfacs-GAT-Fat-3m-Epithelial-nan|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GJB3 LRRIQ1 FOLR1 LRP2

5.90e-051815245ffeca29e4d31a20c110d27af128ed024a79ad56
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SSC5D COMP FN1 CCN1

6.16e-05183524bc7dd6a40ec9c773d005c1a46f305d40cdd0a326
ToppCell(7)_Epithelial-H_(AT1)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

GJB3 DSP FOLR1 NGFR

6.29e-051845241f76b37c265b519171b767a52d48f31f0cdc4a3c
ToppCell3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SSC5D CCN1 MSTN TMEFF2

6.29e-051845244a9f798c67b9998bffe44242b210cc1e224ff5b1
ToppCelldroplet-Kidney-nan-21m-Mesenchymal-fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SSC5D IL22RA2 LRP1 TMEFF2

6.29e-051845243bffadb0cb2e0d825bdb6cfc5d23f5436cbc3efd
ToppCelldroplet-Mammary_Gland-nan-18m-Mesenchymal-nan|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCN1 ENPP2 LRP1 TMEFF2

6.29e-05184524fe4d3def3da4ffdea5ae6bb059f5397efd58fef3
ToppCelldroplet-Kidney-nan-21m-Mesenchymal|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SSC5D IL22RA2 LRP1 TMEFF2

6.42e-0518552433cc0e9d8b54cb7408b51235f2a70e044ebae04d
ToppCellMS-matDC|MS / Condition, Cell_class and T cell subcluster

CCN1 DSP FOLR1 NGFR

6.42e-0518552446bd897349598d85e718e25f9a045d2247723c61
ToppCellMS-matDC-|MS / Condition, Cell_class and T cell subcluster

CCN1 DSP FOLR1 NGFR

6.42e-051855249fbe70d3a7b106fb31e13b7f95029785f28ca6f4
ToppCelldroplet-Kidney-nan-21m-Mesenchymal-Stroma____fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SSC5D IL22RA2 LRP1 TMEFF2

6.42e-051855249954fc85b183c1cc45c3c24e3dadc7984ee6f649
ToppCellIPF-Myeloid-DC_Langerhans|Myeloid / Disease state, Lineage and Cell class

ZEB1 IL22RA2 DSP ENPP2

6.42e-05185524ced17f69486591c3cbbdc852a3e82c3f3a4a30d7
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

ZEB1 ENPP2 PLCB4 SLITRK6

6.69e-0518752413731298bc562ec29582f5da1b4c97261284f6f1
ToppCell3'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FN1 CCN1 CORIN TMEFF2

6.69e-051875246f47a80e612b320f571210483e62ff5db2a8ea43
ToppCelldroplet-Lung-18m-Mesenchymal-myofibroblast-myofibroblast_cell-pulmonary_interstitial_myofibroblast|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SSC5D PNMT ENPP2 CORIN

6.69e-051875248bd635abdee5d5a12a3f7bf74eab4282e8e40741
ToppCelldroplet-Lung-18m-Mesenchymal-myofibroblast-myofibroblast_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SSC5D PNMT ENPP2 CORIN

6.69e-051875243cb8cd7f7a4306ff74d1f7f9964014008ec1c6a0
ToppCellkidney_cells-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FN1 CCN1 ENPP2 PLCB4

6.83e-05188524a37edd8f9e4a4e336b5acbb0407d3d275975cee8
ToppCellNS-critical-d_16-33-Myeloid-Monocyte-derived_DC|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

IL22RA2 FN1 CD163L1 ENPP2

6.83e-0518852408eb1e4b719af53c52895557523d0a1b7421d849
ToppCelldroplet-Limb_Muscle-nan-3m-Mesenchymal-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FN1 ENPP2 LRP1 TMEFF2

6.83e-051885247191087d8754f5e8700e3d744cd920ee26db1e57
ToppCell(2)_Fibroblasts-(20)_Fibro-1|World / Cell class and subclass of bone marrow stroma cells in homeostatis

SSC5D FN1 LRP1 TMEFF2

6.83e-05188524409a7b69d02e87084ca955e3fe6c77230dee8861
ToppCell5'-Adult-Distal_Rectal-Mesenchymal-fibroblastic-Stromal_3_(C7+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SSC5D CCN1 LRP1 CPEB1

6.98e-05189524f7d57723b8fb0f1e1485f51e3eff93ec0f39761e
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Degenerative_Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SSC5D FN1 LRP1 NGFR

6.98e-051895249e1a51997ef9b6999d9b40cf0a55e561e3b4a84c
ToppCelldroplet-Limb_Muscle-nan-24m-Mesenchymal-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VLDLR ENPP2 LRP1 TMEFF2

6.98e-051895246e52cac679e0541ca5f2be316bdabdbc34da6e18
ToppCelldroplet-Mammary_Gland-nan-21m-Mesenchymal-stromal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FN1 ENPP2 LRP1 TMEFF2

6.98e-05189524bc54ffd7bd1627a36747a80ce5139e4a69928400
ToppCelldroplet-Limb_Muscle-nan-21m-Mesenchymal-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FN1 ENPP2 LRP1 TMEFF2

6.98e-051895240a8b827bba1efd885ad6c06929251c741dc3a541
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

LRRIQ1 DSP LRP2 PLCB4

6.98e-051895247659c7bbd58ee959a159294fb8d17317bbcc5681
ToppCelldroplet-Limb_Muscle-nan-21m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FN1 ENPP2 LRP1 TMEFF2

6.98e-0518952456f43e00d81cf3cdf0c39f8d7120f5beab72e258
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ZEB1 FN1 ENPP2 PLCB4

6.98e-051895246463890d8dbee4bc198f91628a5f784970de786a
ToppCellAT2_cells-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

MST1 FOLR1 LRP2 AGRN

6.98e-051895242d32f09efa982ae458568f6b1cd06bb5078d42a3
ToppCelldroplet-Heart-4Chambers-21m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DSP ENPP2 LRP1 CORIN

6.98e-051895242a5fda73d38bdc23cf47e5335ffd4e086e990245
ToppCelldroplet-Mammary_Gland-nan-3m-Mesenchymal|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FN1 ENPP2 LRP1 TMEFF2

7.12e-05190524bd0d68dc1b6f388190a6ba8a83b011619abe2bdd
ComputationalSpinal cord (neuro-development) genes.

ZEB1 FN1 CCN1 DSP ENPP2 LRP1 NGFR

7.27e-05360327MODULE_12
Drugethylnylestradiol

VLDLR GJB3 ZEB1 KRT24 CCN1 ENPP2 LRP1 NGFR LRP2 ACVR2A MSTN LRP1B TG

3.33e-0612515213CID000003285
Druggentamicin

FN1 LRP1 LRP2 PLCB4 SRBD1 MSTN

5.85e-06198526CID000003467
DrugChr 5

VLDLR COMP LRP2 AGRN TG

9.73e-06125525CID006448119
Drugponasterone A

ENPP2 NGFR THAP12 KLRD1

1.98e-0570524CID000115127
DiseaseAlzheimer's disease (is_implicated_in)

VLDLR PNMT LRP1 NGFR

8.77e-05132524DOID:10652 (is_implicated_in)
DiseaseSensory hearing loss

GJB3 LRP2

1.66e-0411522C1691779
Diseaseautoimmune thyroiditis (is_implicated_in)

LRP2 TG

1.99e-0412522DOID:7188 (is_implicated_in)
Diseaseproliferative diabetic retinopathy (is_marker_for)

CCN1 ENPP2

3.60e-0416522DOID:13207 (is_marker_for)
Diseaseportal hypertension (biomarker_via_orthology)

NGFR CPEB1

6.88e-0422522DOID:10762 (biomarker_via_orthology)
DiseaseSensorineural Hearing Loss (disorder)

GJB3 LRP2

7.53e-0423522C0018784
Diseaseinflammatory bowel disease (implicated_via_orthology)

MST1 MST1L

8.90e-0425522DOID:0050589 (implicated_via_orthology)
Diseasecongestive heart failure (biomarker_via_orthology)

NGFR CORIN MSTN

9.00e-04107523DOID:6000 (biomarker_via_orthology)
Diseasehypertension (implicated_via_orthology)

FN1 NGFR LRP2

1.51e-03128523DOID:10763 (implicated_via_orthology)
Diseasefeeling tense measurement

ACVR2A ZC3H7B

1.55e-0333522EFO_0009596
Diseaseexcessive daytime sleepiness measurement

ADAM29 CPEB1

1.55e-0333522EFO_0007875
Diseasepack-years measurement, systolic blood pressure

LRP2 LRP1B

1.65e-0334522EFO_0006335, EFO_0006526
Diseasetriacylglycerol 58:8 measurement

DSP NGFR

1.75e-0335522EFO_0010442

Protein segments in the cluster

PeptideGeneStartEntry
RKEVNECDLPEWCNG

ADAM29

456

Q9UKF5
VKVTGQCCEEWVCDE

CCN1

151

O00622
QCCEEWVCDEDSIKD

CCN1

156

O00622
IEIVKQGCWLDDINC

ACVR2A

71

P27037
EDKWGDACDNCRSQK

COMP

341

P49747
DCEQELCRQRGGIWD

AGRN

681

O00468
CDDSWDLAEAEVVCQ

CD163L1

1271

Q9NR16
AENKQEDCVVVWGEC

RNF7

66

Q9UBF6
KEGQWDCSVCLVRNE

RANBP2

1606

P49792
NKAWVCDGDIDCEDQ

LRP1B

1111

Q9NZR2
WNAVDEEICLAECDI

MAF1

151

Q9H063
WQEDVADAEECAGRC

MST1L

51

Q2TV78
CIQERWKCDGDNDCL

LRP1

866

Q07954
HCCQRLKEEQWEVED

EDEM2

486

Q9BV94
QLELDEDEASCCRWG

PEDS1

11

A5PLL7
EEEICQIWGETKCQN

KRT24

411

Q2M2I5
NKEDCWGTQELSCDL

IL22RA2

106

Q969J5
RCISEEWKCDNDNDC

LRP2

2711

P98164
CEVEEKCRQSFEAWQ

LRRIQ1

161

Q96JM4
CQKWVENCRRADLED

THAP12

31

O43422
SGEKCDEDAWAVCRE

EFCAB7

436

A8K855
GRWKCDPVDQCQDSE

FN1

551

P02751
ETFKELCEQECEWEE

DSP

2491

P15924
EENCGCKERDLWECP

CORIN

611

Q9Y5Q5
DCELWCERVNPENKA

DND1

6

Q8IYX4
ERELEDAWACCETQE

FAM47A

156

Q5JRC9
EEEAGRIKDCWDNQE

CPEB1

6

Q9BZB8
EECNVLQGRWLSDEC

ECI2

366

O75521
WQEDVADAEECAGRC

MST1

46

P26927
ERVWGDEQKDFDCNT

GJB3

41

O75712
WECTKDRCGEVRNEE

ENPP2

101

Q13822
NVPLCKEDCEQWWED

FOLR1

131

P15328
EELCQAWFANCEDDI

RTBDN

116

Q9BSG5
KDDDPNEDWCAVCQN

TRIM33

881

Q9UPN9
CVELDCWDGKGEDQE

PLCB4

356

Q15147
LDLQLEDNKWACNCD

SLITRK6

211

Q9H5Y7
CDEDAEDVWCVCNID

TMEFF2

171

Q9UIK5
ENVEKEGLCNACTWR

MSTN

31

O14793
VCDDNWDLRDATVAC

SSC5D

796

A1L4H1
DGVKDEFCRWCIQNR

SRBD1

456

Q8N5C6
RNCEEEEAWLKECGQ

SPTBN5

646

Q9NRC6
CLIEGKGECWQDKER

PNMT

131

P11086
CEACIQDFWRLQAKE

TRIM69

61

Q86WT6
QLRECTRWADAECEE

NGFR

176

P08138
GNLERECLEERCSWE

PRRG2

61

O14669
QDLDEGCDRWITCKS

ZDHHC23

46

Q8IYP9
NCWEDDRKEGQEILG

ZEB1

81

P37275
RNCWCVDEAGQELEG

TG

896

P01266
LFCQEDGKVICWLCE

TRIM6

106

Q9C030
KCRCAHGQEELNEWL

ZC3H7B

906

Q9UGR2
KVCNQEQDCRDWSDE

VLDLR

336

P98155
EQDCRDWSDEPLKEC

VLDLR

341

P98155
ELQKDSDCCSCQEKW

KLRD1

51

Q13241
VSNGFCEVRERCWKD

N4BP2L2

361

Q92802