Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	RNA polymerase I general transcription initiation factor activity	RRN3P2 RRN3 RRN3P1	2.87e-05	9	142	3	GO:0001181
GeneOntologyMolecularFunction	transmembrane receptor protein tyrosine kinase activity	FLT4 IGF1R IGF2R EFNB3 EPHA3	9.93e-05	65	142	5	GO:0004714
GeneOntologyMolecularFunction	insulin-like growth factor receptor activity	IGF1R IGF2R	1.50e-04	3	142	2	GO:0005010
GeneOntologyMolecularFunction	RNA polymerase I core binding	RRN3P2 RRN3	2.98e-04	4	142	2	GO:0001042
GeneOntologyMolecularFunction	insulin-like growth factor binding	IGF1R IGF2R LRP2	3.14e-04	19	142	3	GO:0005520
GeneOntologyMolecularFunction	transmembrane receptor protein kinase activity	FLT4 IGF1R IGF2R EFNB3 EPHA3	3.52e-04	85	142	5	GO:0019199
GeneOntologyBiologicalProcess	axon guidance	CNTN4 SEMA4D ARHGAP35 TENM2 SEMA4C NRXN3 EFNB3 CELSR3 GLI2 LRP2 UNC5D EPHA3	6.28e-07	285	141	12	GO:0007411
GeneOntologyBiologicalProcess	neuron projection guidance	CNTN4 SEMA4D ARHGAP35 TENM2 SEMA4C NRXN3 EFNB3 CELSR3 GLI2 LRP2 UNC5D EPHA3	6.52e-07	286	141	12	GO:0097485
GeneOntologyBiologicalProcess	synapse organization	CNTN4 SEMA4D CPEB3 HIP1R GRIA1 NECTIN3 PFN1 CSMD2 SEMA4C IGF1R NRXN3 TENM4 EFNB3 FZD5 GPC4 SNX27 EPHA3	4.57e-06	685	141	17	GO:0050808
GeneOntologyBiologicalProcess	transcription initiation at RNA polymerase I promoter	RRN3P2 POLR1E RRN3 RRN3P1	5.94e-06	18	141	4	GO:0006361
GeneOntologyBiologicalProcess	cell-cell adhesion via plasma-membrane adhesion molecules	CNTN4 NECTIN3 TENM2 CELSR1 TENM4 CELSR3 GPC4 UNC5D CDH11 EPHA3 CDHR4	1.05e-05	313	141	11	GO:0098742
GeneOntologyBiologicalProcess	axonogenesis	CNTN4 SEMA4D ARHGAP35 TENM2 SEMA4C IGF1R NRXN3 EFNB3 CELSR3 GLI2 LRP2 UNC5D CDH11 EPHA3	3.46e-05	566	141	14	GO:0007409
GeneOntologyBiologicalProcess	cell junction organization	CNTN4 SEMA4D CPEB3 HIP1R GRIA1 NECTIN3 PFN1 CSMD2 SVEP1 SEMA4C IGF1R NRXN3 TENM4 EFNB3 FZD5 GPC4 SNX27 CDH11 EPHA3	3.65e-05	974	141	19	GO:0034330
GeneOntologyBiologicalProcess	neuron projection fasciculation	CNTN4 ARHGAP35 CELSR3 EPHA3	3.77e-05	28	141	4	GO:0106030
GeneOntologyBiologicalProcess	axonal fasciculation	CNTN4 ARHGAP35 CELSR3 EPHA3	3.77e-05	28	141	4	GO:0007413
GeneOntologyBiologicalProcess	neuron recognition	CNTN4 ARHGAP35 EFNB3 CELSR3 EPHA3	5.17e-05	59	141	5	GO:0008038
GeneOntologyBiologicalProcess	synapse assembly	SEMA4D CPEB3 GRIA1 NECTIN3 CSMD2 SEMA4C NRXN3 EFNB3 FZD5 GPC4	5.25e-05	308	141	10	GO:0007416
GeneOntologyBiologicalProcess	circulatory system development	PCSK5 NPR1 FLT4 ANKS6 HIF3A SVEP1 CEMIP2 STAB1 FREM2 SCUBE1 IGF1R NRXN3 TENM4 FZD5 GLI2 LOXL1 LRP2 ADGRF5 FGF12 IFT122 CDH11 EPHA3 DNMT1	1.18e-04	1442	141	23	GO:0072359
GeneOntologyBiologicalProcess	neuron projection morphogenesis	CNTN4 SEMA4D HECW1 ARHGAP35 TENM2 SEMA4C IGF1R NRXN3 EFNB3 CELSR3 GLI2 LRP2 UNC5D CDH11 MYO16 EPHA3	1.22e-04	802	141	16	GO:0048812
GeneOntologyBiologicalProcess	neural tube closure	ARHGAP35 PFN1 SEMA4C CELSR1 LRP2 IFT122	1.27e-04	113	141	6	GO:0001843
GeneOntologyBiologicalProcess	axon development	CNTN4 SEMA4D ARHGAP35 TENM2 SEMA4C IGF1R NRXN3 EFNB3 CELSR3 GLI2 LRP2 UNC5D CDH11 EPHA3	1.33e-04	642	141	14	GO:0061564
GeneOntologyBiologicalProcess	tube closure	ARHGAP35 PFN1 SEMA4C CELSR1 LRP2 IFT122	1.34e-04	114	141	6	GO:0060606
GeneOntologyBiologicalProcess	plasma membrane bounded cell projection morphogenesis	CNTN4 SEMA4D HECW1 ARHGAP35 TENM2 SEMA4C IGF1R NRXN3 EFNB3 CELSR3 GLI2 LRP2 UNC5D CDH11 MYO16 EPHA3	1.55e-04	819	141	16	GO:0120039
GeneOntologyBiologicalProcess	cell projection morphogenesis	CNTN4 SEMA4D HECW1 ARHGAP35 TENM2 SEMA4C IGF1R NRXN3 EFNB3 CELSR3 GLI2 LRP2 UNC5D CDH11 MYO16 EPHA3	1.70e-04	826	141	16	GO:0048858
GeneOntologyBiologicalProcess	neuron projection development	CNTN4 SEMA4D HECW1 CPEB3 RRN3P2 ARHGAP35 CLIP1 TENM2 SEMA4C IGF1R NRXN3 EFNB3 CELSR3 RRN3 GLI2 LRP2 UNC5D CDH11 MYO16 EPHA3 CPEB1	1.74e-04	1285	141	21	GO:0031175
GeneOntologyBiologicalProcess	primary neural tube formation	ARHGAP35 PFN1 SEMA4C CELSR1 LRP2 IFT122	1.77e-04	120	141	6	GO:0014020
GeneOntologyBiologicalProcess	cell morphogenesis involved in neuron differentiation	CNTN4 SEMA4D HECW1 ARHGAP35 TENM2 SEMA4C IGF1R NRXN3 EFNB3 CELSR3 GLI2 LRP2 UNC5D CDH11 EPHA3	1.90e-04	748	141	15	GO:0048667
GeneOntologyBiologicalProcess	embryo development ending in birth or egg hatching	PCSK5 ANKS6 RRN3P2 ARHGAP35 HM13 PFN1 SEMA4C CELSR1 KMT2D RRN3 FZD5 GLI2 LRP2 ADGRF5 IFT122 ABCG2 DMBT1	2.08e-04	929	141	17	GO:0009792
GeneOntologyBiologicalProcess	transcription by RNA polymerase I	RRN3P2 DHX33 POLR1E RRN3 RRN3P1	2.09e-04	79	141	5	GO:0006360
GeneOntologyBiologicalProcess	neural tube formation	ARHGAP35 PFN1 SEMA4C CELSR1 LRP2 IFT122	3.21e-04	134	141	6	GO:0001841
GeneOntologyBiologicalProcess	morphogenesis of embryonic epithelium	ARHGAP35 PFN1 SEMA4C CELSR1 GLI2 LRP2 IFT122	3.37e-04	190	141	7	GO:0016331
GeneOntologyBiologicalProcess	neuron development	CNTN4 SEMA4D HECW1 CPEB3 RRN3P2 ARHGAP35 CLIP1 TENM2 SEMA4C IGF1R NRXN3 TENM4 EFNB3 CELSR3 RRN3 GLI2 LRP2 UNC5D CDH11 MYO16 EPHA3 CPEB1	3.85e-04	1463	141	22	GO:0048666
GeneOntologyBiologicalProcess	postsynapse assembly	CPEB3 NECTIN3 CSMD2 SEMA4C NRXN3	4.46e-04	93	141	5	GO:0099068
GeneOntologyBiologicalProcess	calcium activated phospholipid scrambling	ANO6 ANO3	4.58e-04	5	141	2	GO:0061588
GeneOntologyBiologicalProcess	calcium activated phosphatidylcholine scrambling	ANO6 ANO3	4.58e-04	5	141	2	GO:0061590
GeneOntologyBiologicalProcess	calcium activated galactosylceramide scrambling	ANO6 ANO3	4.58e-04	5	141	2	GO:0061591
GeneOntologyBiologicalProcess	chordate embryonic development	PCSK5 ANKS6 RRN3P2 ARHGAP35 HM13 PFN1 SEMA4C CELSR1 KMT2D RRN3 FZD5 GLI2 LRP2 ADGRF5 IFT122 DMBT1	4.76e-04	906	141	16	GO:0043009
GeneOntologyBiologicalProcess	neural tube development	ARHGAP35 PFN1 SEMA4C CELSR1 GLI2 LRP2 IFT122	4.87e-04	202	141	7	GO:0021915
GeneOntologyBiologicalProcess	cell junction assembly	SEMA4D CPEB3 GRIA1 NECTIN3 CSMD2 SEMA4C NRXN3 EFNB3 FZD5 GPC4 CDH11 EPHA3	5.46e-04	569	141	12	GO:0034329
GeneOntologyBiologicalProcess	transcytosis	TG IGF1R LRP2	5.70e-04	24	141	3	GO:0045056
GeneOntologyCellularComponent	glutamatergic synapse	CPEB3 HIP1R GRIA1 GRIK4 PFN1 CSMD2 TENM2 SEMA4C IGF1R NRXN3 TENM4 EFNB3 CELSR3 FZD5 GPC4 SNX27 CDH11 CPEB1	9.09e-06	817	140	18	GO:0098978
GeneOntologyCellularComponent	postsynaptic density membrane	GRIA1 GRIK4 NECTIN3 CSMD2 SEMA4C EFNB3 CELSR3	9.19e-05	157	140	7	GO:0098839
GeneOntologyCellularComponent	synaptic membrane	HIP1R GRIA1 GRIK4 NECTIN3 CSMD2 TENM2 SEMA4C NRXN3 EFNB3 CELSR3 KCND1 ANO6 GPC4	1.53e-04	583	140	13	GO:0097060
GeneOntologyCellularComponent	postsynaptic specialization membrane	GRIA1 GRIK4 NECTIN3 CSMD2 SEMA4C EFNB3 CELSR3	4.18e-04	201	140	7	GO:0099634
GeneOntologyCellularComponent	endocytic vesicle membrane	GRIA1 STAB1 COLEC12 IGF2R FZD5 LRP2 DMBT1	5.75e-04	212	140	7	GO:0030666
Domain	EGF	PCSK5 TENM2 SVEP1 STAB1 SCUBE1 CELSR1 NRXN3 TENM4 CELSR3 UMODL1 TLL2 LRP2	1.94e-07	235	139	12	SM00181
Domain	Pectin_lyase_fold/virulence	FBXO11 PKHD1L1 CEMIP2 SHCBP1	2.01e-07	8	139	4	IPR011050
Domain	EGF_CA	TENM2 SVEP1 STAB1 SCUBE1 CELSR1 CELSR3 UMODL1 TLL2 LRP2	3.23e-07	122	139	9	SM00179
Domain	EGF-like_dom	PCSK5 TENM2 SVEP1 STAB1 SCUBE1 CELSR1 NRXN3 TENM4 CELSR3 UMODL1 TLL2 LRP2	3.61e-07	249	139	12	IPR000742
Domain	EGF-like_Ca-bd_dom	TENM2 SVEP1 STAB1 SCUBE1 CELSR1 CELSR3 UMODL1 TLL2 LRP2	3.71e-07	124	139	9	IPR001881
Domain	EGF_2	TENM2 SVEP1 STAB1 SCUBE1 CELSR1 NRXN3 TENM4 CELSR3 UMODL1 TLL2 LRP2 EPHA3	7.01e-07	265	139	12	PS01186
Domain	Ephrin_rec_like	SVEP1 TG SCUBE1 EPHA3	9.31e-07	11	139	4	PF07699
Domain	Ephrin_rec_like	PCSK5 SVEP1 TG SCUBE1 EPHA3	1.00e-06	25	139	5	SM01411
Domain	Tyr-kin_ephrin_A/B_rcpt-like	PCSK5 SVEP1 TG SCUBE1 EPHA3	1.00e-06	25	139	5	IPR011641
Domain	EGF-type_Asp/Asn_hydroxyl_site	SVEP1 SCUBE1 CELSR1 NRXN3 CELSR3 UMODL1 TLL2 LRP2	1.26e-06	106	139	8	IPR000152
Domain	EGF_3	TENM2 SVEP1 STAB1 SCUBE1 CELSR1 NRXN3 TENM4 CELSR3 UMODL1 TLL2 LRP2	1.51e-06	235	139	11	PS50026
Domain	Growth_fac_rcpt_	PCSK5 SVEP1 STAB1 SCUBE1 CELSR1 IGF1R UMODL1 LRP2 EPHA3	2.55e-06	156	139	9	IPR009030
Domain	CUB	ADAMTS13 CSMD2 SCUBE1 TLL2 LRP3 DMBT1	2.63e-06	53	139	6	PS01180
Domain	EGF_1	TENM2 SVEP1 STAB1 SCUBE1 CELSR1 NRXN3 TENM4 CELSR3 UMODL1 TLL2 LRP2	3.32e-06	255	139	11	PS00022
Domain	YIPPEE	YPEL3 YPEL2 YPEL1	3.99e-06	5	139	3	PS51792
Domain	CUB_dom	ADAMTS13 CSMD2 SCUBE1 TLL2 LRP3 DMBT1	4.05e-06	57	139	6	IPR000859
Domain	EGF-like_CS	TENM2 SVEP1 STAB1 SCUBE1 CELSR1 NRXN3 TENM4 CELSR3 UMODL1 TLL2 LRP2	4.15e-06	261	139	11	IPR013032
Domain	PbH1	FBXO11 PKHD1L1 SHCBP1	7.94e-06	6	139	3	SM00710
Domain	PbH1	FBXO11 PKHD1L1 SHCBP1	7.94e-06	6	139	3	IPR006626
Domain	ASX_HYDROXYL	SVEP1 SCUBE1 CELSR1 NRXN3 CELSR3 UMODL1 LRP2	9.77e-06	100	139	7	PS00010
Domain	Yippee/Mis18/Cereblon	YPEL3 YPEL2 YPEL1	2.20e-05	8	139	3	IPR004910
Domain	Yippee-Mis18	YPEL3 YPEL2 YPEL1	2.20e-05	8	139	3	PF03226
Domain	CUB	CSMD2 SCUBE1 TLL2 LRP3 DMBT1	3.11e-05	49	139	5	PF00431
Domain	CUB	CSMD2 SCUBE1 TLL2 LRP3 DMBT1	3.44e-05	50	139	5	SM00042
Domain	-	CSMD2 SCUBE1 TLL2 LRP3 DMBT1	4.17e-05	52	139	5	2.60.120.290
Domain	EGF	SVEP1 STAB1 CELSR1 NRXN3 CELSR3 TLL2 LRP2	4.39e-05	126	139	7	PF00008
Domain	Rhs_assc_core	TENM2 TENM4	1.64e-04	3	139	2	IPR022385
Domain	Tox-GHH_dom	TENM2 TENM4	3.27e-04	4	139	2	IPR028916
Domain	G8_domain	PKHD1L1 CEMIP2	3.27e-04	4	139	2	IPR019316
Domain	G8	PKHD1L1 CEMIP2	3.27e-04	4	139	2	PS51484
Domain	Tox-GHH	TENM2 TENM4	3.27e-04	4	139	2	PF15636
Domain	CEBP_ZZ	CPEB3 CPEB1	3.27e-04	4	139	2	PF16366
Domain	RRM_7	CPEB3 CPEB1	3.27e-04	4	139	2	PF16367
Domain	G8	PKHD1L1 CEMIP2	3.27e-04	4	139	2	SM01225
Domain	CEBP_ZZ	CPEB3 CPEB1	3.27e-04	4	139	2	IPR032296
Domain	Ten_N	TENM2 TENM4	3.27e-04	4	139	2	IPR009471
Domain	Ten_N	TENM2 TENM4	3.27e-04	4	139	2	PF06484
Domain	G8	PKHD1L1 CEMIP2	3.27e-04	4	139	2	PF10162
Domain	TENEURIN_N	TENM2 TENM4	3.27e-04	4	139	2	PS51361
Domain	EGF_CA	SVEP1 SCUBE1 UMODL1 TLL2 LRP2	4.56e-04	86	139	5	PF07645
Domain	YD	TENM2 TENM4	5.42e-04	5	139	2	IPR006530
Domain	EGF_Ca-bd_CS	SVEP1 SCUBE1 UMODL1 TLL2 LRP2	7.91e-04	97	139	5	IPR018097
Domain	Pectin_lyas_fold	FBXO11 SHCBP1	8.09e-04	6	139	2	IPR012334
Domain	-	FBXO11 SHCBP1	8.09e-04	6	139	2	2.160.20.10
Domain	EGF_CA	SVEP1 SCUBE1 UMODL1 TLL2 LRP2	8.68e-04	99	139	5	PS01187
Domain	GPCR_2-like	CELSR1 CELSR3 FZD5 ADGRF5	1.04e-03	60	139	4	IPR017981
Domain	EGF_extracell	SVEP1 STAB1 TENM4 LRP2	1.04e-03	60	139	4	IPR013111
Domain	EGF_2	SVEP1 STAB1 TENM4 LRP2	1.04e-03	60	139	4	PF07974
Domain	G_PROTEIN_RECEP_F2_4	CELSR1 CELSR3 FZD5 ADGRF5	1.10e-03	61	139	4	PS50261
Domain	Anoct_dimer	ANO6 ANO3	1.13e-03	7	139	2	PF16178
Domain	Anoct_dimer	ANO6 ANO3	1.13e-03	7	139	2	IPR032394
Domain	EGF_LAM_2	STAB1 CELSR1 CELSR3	1.41e-03	30	139	3	PS50027
Domain	EGF_LAM_1	STAB1 CELSR1 CELSR3	1.41e-03	30	139	3	PS01248
Domain	CA	FREM2 CELSR1 CELSR3 CDH11 CDHR4	1.69e-03	115	139	5	SM00112
Domain	Cadherin	FREM2 CELSR1 CELSR3 CDH11 CDHR4	1.90e-03	118	139	5	IPR002126
Domain	GPS	CELSR1 CELSR3 ADGRF5	2.04e-03	34	139	3	SM00303
Domain	EGF_Lam	STAB1 CELSR1 CELSR3	2.22e-03	35	139	3	SM00180
Domain	GPS	CELSR1 CELSR3 ADGRF5	2.22e-03	35	139	3	PF01825
Domain	Laminin_EGF	STAB1 CELSR1 CELSR3	2.22e-03	35	139	3	PF00053
Domain	Anoctamin	ANO6 ANO3	2.38e-03	10	139	2	PF04547
Domain	Anoctamin	ANO6 ANO3	2.38e-03	10	139	2	IPR007632
Domain	GPS	CELSR1 CELSR3 ADGRF5	2.41e-03	36	139	3	PS50221
Domain	ANF_lig-bd_rcpt	NPR1 GRIA1 GRIK4	2.60e-03	37	139	3	IPR001828
Domain	ANF_receptor	NPR1 GRIA1 GRIK4	2.60e-03	37	139	3	PF01094
Domain	GPS	CELSR1 CELSR3 ADGRF5	2.60e-03	37	139	3	IPR000203
Domain	Pkinase_Tyr	NPR1 FLT4 MLKL IGF1R EPHA3	2.80e-03	129	139	5	PF07714
Domain	LAM_G_DOMAIN	CELSR1 NRXN3 CELSR3	2.81e-03	38	139	3	PS50025
Domain	Laminin_EGF	STAB1 CELSR1 CELSR3	2.81e-03	38	139	3	IPR002049
Domain	GFP-like	SVEP1 STAB1	2.89e-03	11	139	2	IPR023413
Domain	-	SVEP1 STAB1	2.89e-03	11	139	2	2.40.155.10
Domain	GAIN_dom_N	CELSR1 CELSR3	2.89e-03	11	139	2	IPR032471
Domain	GAIN	CELSR1 CELSR3	2.89e-03	11	139	2	PF16489
Domain	ig	CNTN4 SEMA4D FLT4 ADGRF5 IGSF1 UNC5D	3.01e-03	190	139	6	PF00047
Domain	Immunoglobulin	CNTN4 SEMA4D FLT4 ADGRF5 IGSF1 UNC5D	3.01e-03	190	139	6	IPR013151
Domain	Peripla_BP_I	NPR1 GRIA1 GRIK4	3.03e-03	39	139	3	IPR028082
Domain	-	TENM2 TENM4 LRP2	3.03e-03	39	139	3	2.120.10.30
Domain	GPCR_2_extracellular_dom	CELSR1 CELSR3 ADGRF5	3.26e-03	40	139	3	IPR001879
Domain	G_PROTEIN_RECEP_F2_1	CELSR1 CELSR3 ADGRF5	3.26e-03	40	139	3	PS00649
Domain	Laminin_G_2	CELSR1 NRXN3 CELSR3	3.26e-03	40	139	3	PF02210
Domain	G_PROTEIN_RECEP_F2_3	CELSR1 CELSR3 ADGRF5	3.26e-03	40	139	3	PS50227
Domain	EGF_dom	STAB1 SCUBE1	3.46e-03	12	139	2	IPR024731
Domain	EGF_3	STAB1 SCUBE1	3.46e-03	12	139	2	PF12947
Domain	Ser-Thr/Tyr_kinase_cat_dom	NPR1 FLT4 MLKL IGF1R EPHA3	3.73e-03	138	139	5	IPR001245
Domain	-	CNTN4 SEMA4D FLT4 NECTIN3 PKHD1L1 SEMA4C IGF1R UMODL1 ADGRF5 IGSF1 UNC5D EPHA3	3.99e-03	663	139	12	2.60.40.10
Domain	NHL	TENM2 TENM4	4.06e-03	13	139	2	PS51125
Domain	LamG	CELSR1 NRXN3 CELSR3	4.27e-03	44	139	3	SM00282
Domain	ZP_2	UMODL1 DMBT1	4.72e-03	14	139	2	PS51034
Domain	ZP_1	UMODL1 DMBT1	4.72e-03	14	139	2	PS00682
Domain	6-blade_b-propeller_TolB-like	TENM2 TENM4 LRP2	4.85e-03	46	139	3	IPR011042
Domain	ZP	UMODL1 DMBT1	5.42e-03	15	139	2	SM00241
Domain	-	SVEP1 CELSR1 NRXN3 CELSR3	5.54e-03	95	139	4	2.60.120.200
Domain	7tm_2	CELSR1 CELSR3 ADGRF5	6.12e-03	50	139	3	PF00002
Domain	G_PROTEIN_RECEP_F2_2	CELSR1 CELSR3 ADGRF5	6.12e-03	50	139	3	PS00650
Domain	Ig-like_fold	CNTN4 SEMA4D FLT4 NECTIN3 PKHD1L1 SEMA4C IGF1R UMODL1 ADGRF5 IGSF1 UNC5D EPHA3	6.52e-03	706	139	12	IPR013783
Domain	DUF1605	DHX33 DHX34	6.95e-03	17	139	2	IPR011709
Domain	CarboxyPept-like_regulatory	TENM2 TENM4	6.95e-03	17	139	2	IPR008969
Domain	ZP_dom	UMODL1 DMBT1	6.95e-03	17	139	2	IPR001507
Domain	Zona_pellucida	UMODL1 DMBT1	6.95e-03	17	139	2	PF00100
Domain	OB_NTP_bind	DHX33 DHX34	6.95e-03	17	139	2	PF07717
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	HIP1R NPLOC4 CEMIP2 STAB1 NRXN3 PSME4 CELSR3 MED12L NUP188 IGSF1 ESPL1 DHX34 ZMYM4	3.46e-07	529	144	13	14621295
Pubmed	Identification and characterization of a novel gene family YPEL in a wide spectrum of eukaryotic species.	YPEL3 YPEL2 YPEL1	6.91e-07	5	144	3	15556292
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	PCSK5 ANKS6 ATP13A1 HIP1R ARHGAP35 CELSR1 KMT2D IGF1R IGF2R PSME4 CELSR3 A4GALT LRP3 IRS2 NUP188 ESPL1 DHX34 ATPAF2	7.99e-07	1105	144	18	35748872
Pubmed	Centrosome-related genes, genetic variation, and risk of breast cancer.	YPEL3 KIF23 YPEL2 YPEL1 TNKS ESPL1	4.41e-06	102	144	6	20508983
Pubmed	Defining the human deubiquitinating enzyme interaction landscape.	FBXO11 DHX33 FBXO17 NPLOC4 IGF2R POLR1E RRN3 RPTN SHCBP1 SPRYD3 SNX27 TNKS NUP188 ZMYM4 TP53BP1 DNMT1	4.57e-06	1005	144	16	19615732
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	KIF23 ANKS6 LBR PFN1 PKHD1L1 PPL CEMIP2 SEMA4C ARFGEF3 IGF2R ANO6 EIF2B4 ANO3 DNMT1	4.66e-06	777	144	14	35844135
Pubmed	Insulin-like growth factor axis gene polymorphisms and clinical outcomes in pancreatic cancer.	IGF1R IGF2R IRS2	8.17e-06	10	144	3	20416304
Pubmed	Insulin-like growth factor axis gene polymorphisms modify risk of pancreatic cancer.	IGF1R IGF2R IRS2	8.17e-06	10	144	3	21852217
Pubmed	YPEL5 protein of the YPEL gene family is involved in the cell cycle progression by interacting with two distinct proteins RanBPM and RanBP10.	YPEL3 YPEL2 YPEL1	8.17e-06	10	144	3	20580816
Pubmed	Rrn3 phosphorylation is a regulatory checkpoint for ribosome biogenesis.	RRN3P2 RRN3	1.70e-05	2	144	2	12015311
Pubmed	A neuroprotective phase precedes striatal degeneration upon nucleolar stress.	RRN3P2 RRN3	1.70e-05	2	144	2	23764776
Pubmed	Neuronal IGF-1 resistance reduces Abeta accumulation and protects against premature death in a model of Alzheimer's disease.	IGF1R IRS2	1.70e-05	2	144	2	19487308
Pubmed	Non-motor symptoms associated with progressive loss of dopaminergic neurons in a mouse model of Parkinson's disease.	RRN3P2 RRN3	1.70e-05	2	144	2	38745938
Pubmed	Function of the growth-regulated transcription initiation factor TIF-IA in initiation complex formation at the murine ribosomal gene promoter.	RRN3P2 RRN3	1.70e-05	2	144	2	8413268
Pubmed	[Relationship of insulin-like growth factor receptor single nucleotide polymorphism (SNP) with platinum-based chemotherapy outcomes in advanced non-small cell lung cancer].	IGF1R IGF2R	1.70e-05	2	144	2	22336232
Pubmed	Stimulation of noradrenergic transmission by reboxetine is beneficial for a mouse model of progressive parkinsonism.	RRN3P2 RRN3	1.70e-05	2	144	2	30918302
Pubmed	Choroid plexus megalin is involved in neuroprotection by serum insulin-like growth factor I.	IGF1R LRP2	1.70e-05	2	144	2	16306401
Pubmed	Heat shock represses rRNA synthesis by inactivation of TIF-IA and lncRNA-dependent changes in nucleosome positioning.	RRN3P2 RRN3	1.70e-05	2	144	2	27257073
Pubmed	ERK-dependent phosphorylation of the transcription initiation factor TIF-IA is required for RNA polymerase I transcription and cell growth.	RRN3P2 RRN3	1.70e-05	2	144	2	12620228
Pubmed	The role of GLI2-ABCG2 signaling axis for 5Fu resistance in gastric cancer.	GLI2 ABCG2	1.70e-05	2	144	2	28847472
Pubmed	Insulin-like growth factors I and II receptors in the breast cancer survival disparity among African-American women.	IGF1R IGF2R	1.70e-05	2	144	2	20347606
Pubmed	The role of insulin-like growth factor in Acrochordon Etiopathology.	IGF1R IGF2R	1.70e-05	2	144	2	33143702
Pubmed	Essential role of insulin receptor substrate-2 in insulin stimulation of Glut4 translocation and glucose uptake in brown adipocytes.	IGF1R IRS2	1.70e-05	2	144	2	10829031
Pubmed	Integration of the Deacetylase SIRT1 in the Response to Nucleolar Stress: Metabolic Implications for Neurodegenerative Diseases.	RRN3P2 RRN3	1.70e-05	2	144	2	31110473
Pubmed	DNA binding by the ribosomal DNA transcription factor rrn3 is essential for ribosomal DNA transcription.	RRN3P2 RRN3	1.70e-05	2	144	2	23393135
Pubmed	Quantitative analysis of insulin-like growth factor 2 receptor and insulin-like growth factor binding proteins to identify control mechanisms for insulin-like growth factor 1 receptor phosphorylation.	IGF1R IGF2R	1.70e-05	2	144	2	26861122
Pubmed	Impaired rRNA synthesis triggers homeostatic responses in hippocampal neurons.	RRN3P2 RRN3	1.70e-05	2	144	2	24273493
Pubmed	Megalin (gp330): a putative endocytic receptor for thyroglobulin (Tg).	TG LRP2	1.70e-05	2	144	2	9492085
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	KIF23 ARHGAP35 CLIP1 PPL KMT2D SHCBP1 HELZ IRS2 ESPL1 UNC5D ZMYM4 TP53BP1 DNMT1	2.16e-05	774	144	13	15302935
Pubmed	A genomic atlas of mouse hypothalamic development.	YPEL2 NECTIN3 TENM2 CEMIP2 SHCBP1 IGSF1 EPHA3	2.48e-05	205	144	7	20436479
Pubmed	Interrogating the protein interactomes of RAS isoforms identifies PIP5K1A as a KRAS-specific vulnerability.	SEMA4D NECTIN3 LBR HM13 CEMIP2 SEMA4C CHMP7 IGF2R EFNB3 EPHA3	2.68e-05	467	144	10	30194290
Pubmed	A dual-strategy expression screen for candidate connectivity labels in the developing thalamus.	TENM2 TENM4 EFNB3 CDH11 EPHA3	3.96e-05	91	144	5	28558017
Pubmed	Effects of insulin-like growth factors-IR and -IIR antisense gene transfection on the biological behaviors of SMMC-7721 human hepatoma cells.	IGF1R IGF2R	5.09e-05	3	144	2	12603530
Pubmed	Semaphorin 4A, 4C, and 4D: Function comparison in the autoimmunity, allergy, and cancer.	SEMA4D SEMA4C	5.09e-05	3	144	2	32244055
Pubmed	Targeted gene mutations define the roles of insulin and IGF-I receptors in mouse embryonic development.	IGF1R IRS2	5.09e-05	3	144	2	10417963
Pubmed	Impact of insulin-like growth factor 2, insulin-like growth factor receptor 2, insulin receptor substrate 2 genes polymorphisms on susceptibility and clinicopathological features of hepatocellular carcinoma.	IGF2R IRS2	5.09e-05	3	144	2	24656929
Pubmed	Mouse mutants lacking the cation-independent mannose 6-phosphate/insulin-like growth factor II receptor are impaired in lysosomal enzyme transport: comparison of cation-independent and cation-dependent mannose 6-phosphate receptor-deficient mice.	IGF1R IGF2R	5.09e-05	3	144	2	9480908
Pubmed	Plexin B2 and Semaphorin 4C Guide T Cell Recruitment and Function in the Germinal Center.	SEMA4D SEMA4C	5.09e-05	3	144	2	28467912
Pubmed	Astrocyte glypicans 4 and 6 promote formation of excitatory synapses via GluA1 AMPA receptors.	GRIA1 GPC4	5.09e-05	3	144	2	22722203
Pubmed	The flamingo-related mouse Celsr family (Celsr1-3) genes exhibit distinct patterns of expression during embryonic development.	CELSR1 CELSR3	5.09e-05	3	144	2	11677057
Pubmed	CPEB4 is a cell survival protein retained in the nucleus upon ischemia or endoplasmic reticulum calcium depletion.	CPEB3 CPEB1	5.09e-05	3	144	2	20937770
Pubmed	Beneficial synergistic interactions of TNF-alpha and IL-6 in C2 skeletal myoblasts--potential cross-talk with IGF system.	IGF1R IGF2R	5.09e-05	3	144	2	18428025
Pubmed	Insulin receptor substrate-2 mediated insulin-like growth factor-I receptor overexpression in pancreatic adenocarcinoma through protein kinase Cdelta.	IGF1R IRS2	5.09e-05	3	144	2	19190347
Pubmed	A/ASP/VAL allele combination of IGF1R, IRS2, and UCP2 genes is associated with better metabolic profile, preserved energy expenditure parameters, and low mortality rate in longevity.	IGF1R IRS2	5.09e-05	3	144	2	21340542
Pubmed	Study on insulin resistance and genetic polymorphisms in essential hypertension patients of two different kinds of TCM constitution.	IGF1R IRS2	5.09e-05	3	144	2	17898946
Pubmed	TAF12 recruits Gadd45a and the nucleotide excision repair complex to the promoter of rRNA genes leading to active DNA demethylation.	RRN3P2 RRN3	5.09e-05	3	144	2	19217408
Pubmed	Nuclear IGF1R interacts with NuMA and regulates 53BP1‑dependent DNA double‑strand break repair in colorectal cancer.	IGF1R TP53BP1	5.09e-05	3	144	2	34165167
Pubmed	CPEB3 and CPEB4 in neurons: analysis of RNA-binding specificity and translational control of AMPA receptor GluR2 mRNA.	CPEB3 CPEB1	5.09e-05	3	144	2	17024188
Pubmed	Nucleolar stress controls mutant Huntington toxicity and monitors Huntington's disease progression.	RRN3P2 RRN3	5.09e-05	3	144	2	34880223
Pubmed	Emotional Stress Induces Structural Plasticity in Bergmann Glial Cells via an AC5-CPEB3-GluA1 Pathway.	CPEB3 GRIA1	5.09e-05	3	144	2	32229518
Pubmed	Decreased IGF type 1 receptor signaling in mammary epithelium during pregnancy leads to reduced proliferation, alveolar differentiation, and expression of insulin receptor substrate (IRS)-1 and IRS-2.	IGF1R IRS2	5.09e-05	3	144	2	21628386
Pubmed	IGF-1R, a target of let-7b, mediates crosstalk between IRS-2/Akt and MAPK pathways to promote proliferation of oral squamous cell carcinoma.	IGF1R IRS2	5.09e-05	3	144	2	24810113
Pubmed	Correlation of IGF1R expression with ABCG2 and CD44 expressions in human osteosarcoma.	IGF1R ABCG2	5.09e-05	3	144	2	29892839
Pubmed	Chromosomal localization of human genes for the LDL receptor family member glycoprotein 330 (LRP2) and its associated protein RAP (LRPAP1).	LRP2 LRP3	5.09e-05	3	144	2	7959795
Pubmed	Global genetic analysis in mice unveils central role for cilia in congenital heart disease.	PCSK5 ANKS6 FREM2 PSME4 LRP2	6.23e-05	100	144	5	25807483
Pubmed	Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins.	NPR1 FLT4 IGF1R LRP2 SNX27	6.53e-05	101	144	5	23382219
Pubmed	An extracellular biochemical screen reveals that FLRTs and Unc5s mediate neuronal subtype recognition in the retina.	CNTN4 SEMA4D SEMA4C UNC5D	6.54e-05	52	144	4	26633812
Pubmed	The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.	BGN COLEC12 FREM2 LOXL1 FGB DMBT1	7.22e-05	167	144	6	22159717
Pubmed	The transcription factor neurogenin 2 restricts cell migration from the cortex to the striatum.	EFNB3 CDH11 EPHA3	7.53e-05	20	144	3	11748150
Pubmed	Human variation in alcohol response is influenced by variation in neuronal signaling genes.	CNTN4 GRIK4 ADAMTS13 IGF1R GLI2 MYO16	8.23e-05	171	144	6	20201926
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	PCSK5 SRP72 NPLOC4 CEMIP2 FREM2 PSME4 SHCBP1 HELZ IFT122 DHX34 DNMT1	8.86e-05	650	144	11	38777146
Pubmed	Polydom/SVEP1 binds to Tie1 and promotes migration of lymphatic endothelial cells.	FLT4 SVEP1	1.02e-04	4	144	2	37338522
Pubmed	Mouse ten-m/Odz is a new family of dimeric type II transmembrane proteins expressed in many tissues.	TENM2 TENM4	1.02e-04	4	144	2	10225957
Pubmed	Two previously undescribed members of the mouse CPEB family of genes and their inducible expression in the principal cell layers of the hippocampus.	CPEB3 CPEB1	1.02e-04	4	144	2	12871996
Pubmed	Role for DNA methylation in genomic imprinting.	IGF2R DNMT1	1.02e-04	4	144	2	8247133
Pubmed	Genetic analysis of type-1 insulin-like growth factor receptor signaling through insulin receptor substrate-1 and -2 in pancreatic beta cells.	IGF1R IRS2	1.02e-04	4	144	2	20947509
Pubmed	Expression of insulin-like growth factors IGF-I and IGF-II, and their receptors during the growth and megakaryocytic differentiation of K562 cells.	IGF1R IGF2R	1.02e-04	4	144	2	12127559
Pubmed	The adhesion GPCRs CELSR1-3 and LPHN3 engage G proteins via distinct activation mechanisms.	CELSR1 CELSR3	1.02e-04	4	144	2	37224017
Pubmed	Involvement of IGF-2, IGF-1R, IGF-2R and PTEN in development of human tooth germ - an immunohistochemical study.	IGF1R IGF2R	1.02e-04	4	144	2	27326759
Pubmed	Regulation of insulin-like growth factor receptors by Ubiquilin1.	IGF1R IGF2R	1.02e-04	4	144	2	29054976
Pubmed	IRS-2 deubiquitination by USP9X maintains anchorage-independent cell growth via Erk1/2 activation in prostate carcinoma cell line.	IGF1R IRS2	1.02e-04	4	144	2	30338032
Pubmed	Insulin receptor substrate-2 binds to the insulin receptor through its phosphotyrosine-binding domain and through a newly identified domain comprising amino acids 591-786.	IGF1R IRS2	1.02e-04	4	144	2	8626379
Pubmed	Efficient translation of Dnmt1 requires cytoplasmic polyadenylation and Musashi binding elements.	CPEB1 DNMT1	1.02e-04	4	144	2	24586322
Pubmed	Effect of insulin-like-growth factor and its receptors regarding lung development in fetal mice.	IGF1R IGF2R	1.02e-04	4	144	2	17653731
Pubmed	Differential activation of insulin receptor substrates 1 and 2 by insulin-like growth factor-activated insulin receptors.	IGF1R IRS2	1.02e-04	4	144	2	17325037
Pubmed	Insulin-like growth factor I receptor signaling and nuclear translocation of insulin receptor substrates 1 and 2.	IGF1R IRS2	1.02e-04	4	144	2	12554758
Pubmed	Genomic imprinting disrupted by a maternal effect mutation in the Dnmt1 gene.	IGF2R DNMT1	1.02e-04	4	144	2	11290321
Pubmed	Immunolocalization of insulin-like growth factors and their receptors in the diabetic mouse oviduct and uterine tissues during the preimplantation period.	IGF1R IGF2R	1.02e-04	4	144	2	18676006
Pubmed	Insulin receptor substrate 2 and Shc play different roles in insulin-like growth factor I signaling.	IGF1R IRS2	1.02e-04	4	144	2	9852124
Pubmed	Interaction of insulin receptor substrate-2 (IRS-2) with the insulin and insulin-like growth factor I receptors. Evidence for two distinct phosphotyrosine-dependent interaction domains within IRS-2.	IGF1R IRS2	1.02e-04	4	144	2	8662806
Pubmed	All four members of the Ten-m/Odz family of transmembrane proteins form dimers.	TENM2 TENM4	1.02e-04	4	144	2	12000766
Pubmed	Association of the polycystic ovary syndrome with genomic variants related to insulin resistance, type 2 diabetes mellitus, and obesity.	IGF1R IGF2R	1.02e-04	4	144	2	15181035
Pubmed	Developmental expression profiles of Celsr (Flamingo) genes in the mouse.	CELSR1 CELSR3	1.02e-04	4	144	2	11850187
Pubmed	No association between genetic or epigenetic variation in insulin growth factors and antipsychotic-induced metabolic disturbances in a cross-sectional sample.	IGF1R IGF2R	1.02e-04	4	144	2	24956249
Pubmed	Akt activation enhances ribosomal RNA synthesis through casein kinase II and TIF-IA.	RRN3P2 RRN3	1.02e-04	4	144	2	24297901
Pubmed	Genetic mutations linked to Parkinson's disease differentially control nucleolar activity in pre-symptomatic mouse models.	RRN3P2 RRN3	1.02e-04	4	144	2	28360124
Pubmed	Mouse mutants lacking the type 2 IGF receptor (IGF2R) are rescued from perinatal lethality in Igf2 and Igf1r null backgrounds.	IGF1R IGF2R	1.02e-04	4	144	2	8806828
Pubmed	Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.	CNTN4 FLT4 ATP13A1 ADAMTS13 FREM2 FGB ADGRF5	1.03e-04	257	144	7	16335952
Pubmed	Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis.	ATP13A1 SRP72 LBR HM13 NPLOC4 CEMIP2 CHMP7 ORC2 VPS13D ANO6	1.36e-04	568	144	10	37774976
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	NPR1 NECTIN3 LBR H6PD HM13 CEMIP2 BGN CELSR1 IGF1R IGF2R CELSR3 ANO6 LOXL1 A4GALT DNMT1	1.45e-04	1201	144	15	35696571
Pubmed	FAM105A/OTULINL Is a Pseudodeubiquitinase of the OTU-Class that Localizes to the ER Membrane.	ATP13A1 LBR FBXO17 HM13 CEMIP2 SEMA4C CHMP7 IGF2R ANO6	1.54e-04	468	144	9	31056421
Pubmed	Deficiency of Wdr60 and Wdr34 cause distinct neural tube malformation phenotypes in early embryos.	CELSR1 CELSR3 GLI2	1.69e-04	26	144	3	37228654
Pubmed	Growth-promoting interaction of IGF-II with the insulin receptor during mouse embryonic development.	IGF1R IGF2R	1.69e-04	5	144	2	9281335
Pubmed	The insulin-like growth factor type 1 and insulin-like growth factor type 2/mannose-6-phosphate receptors independently regulate ERK1/2 activity in HEK293 cells.	IGF1R IGF2R	1.69e-04	5	144	2	17620336
Pubmed	Phosphorylation by casein kinase 2 facilitates rRNA gene transcription by promoting dissociation of TIF-IA from elongating RNA polymerase I.	RRN3P2 RRN3	1.69e-04	5	144	2	18559419
Pubmed	The phosphotyrosine interactome of the insulin receptor family and its substrates IRS-1 and IRS-2.	IGF1R IRS2	1.69e-04	5	144	2	19001411
Pubmed	The nucleolus as a stress sensor: JNK2 inactivates the transcription factor TIF-IA and down-regulates rRNA synthesis.	RRN3P2 RRN3	1.69e-04	5	144	2	15805466
Pubmed	Genetic variation in insulin-like growth factors and brain tumor risk.	IGF1R IGF2R	1.69e-04	5	144	2	18562769
Pubmed	Large-scale analysis of variation in the insulin-like growth factor family in humans reveals rare disease links and common polymorphisms.	IGF1R IGF2R	1.69e-04	5	144	2	28389567
Pubmed	Pharmacogenetics of telatinib, a VEGFR-2 and VEGFR-3 tyrosine kinase inhibitor, used in patients with solid tumors.	FLT4 ABCG2	1.69e-04	5	144	2	19924384
Interaction	LGALS1 interactions	SEMA4D FLT4 KIF23 NECTIN3 CEMIP2 SEMA4C COLEC12 FREM2 IGF1R IGF2R EFNB3 LRP2	4.21e-06	332	142	12	int:LGALS1
Interaction	FBXO2 interactions	PCSK5 SEMA4D NECTIN3 H6PD CEMIP2 SEMA4C COLEC12 IGF1R IGF2R CELSR3 ANO6 LRP2 CDHR4	7.05e-06	411	142	13	int:FBXO2
GeneFamily	Yippee like family	YPEL3 YPEL2 YPEL1	1.63e-06	5	100	3	1130
GeneFamily	Adhesion G protein-coupled receptors, subfamily C\|CELSR cadherins	CELSR1 CELSR3	9.05e-05	3	100	2	913
GeneFamily	Adhesion G protein-coupled receptors, subfamily C\|CELSR cadherins	CELSR1 CELSR3	9.05e-05	3	100	2	1189
GeneFamily	Immunoglobulin like domain containing	CNTN4 SEMA4D FLT4 NECTIN3 SEMA4C ADGRF5 IGSF1	9.82e-05	193	100	7	594
GeneFamily	Anoctamins	ANO6 ANO3	1.32e-03	10	100	2	865
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	CNTN4 FLT4 NECTIN3 ADGRF5 UNC5D	2.01e-03	161	100	5	593
GeneFamily	Low density lipoprotein receptors	LRP2 LRP3	2.27e-03	13	100	2	634
GeneFamily	Zinc fingers\|Zinc fingers PARP-type\|Poly(ADP-ribose) polymerases	TRAF3 NPLOC4	3.03e-03	15	100	2	26
GeneFamily	DEAH-box helicases	DHX33 DHX34	3.46e-03	16	100	2	500
GeneFamily	Immunoglobulin like domain containing\|Semaphorins	SEMA4D SEMA4C	5.39e-03	20	100	2	736
Coexpression	LI_CISPLATIN_RESISTANCE_UP	CEMIP2 IGF1R ANO3 EPHA3	1.16e-05	26	143	4	M4717
Coexpression	GSE30083_SP2_VS_SP4_THYMOCYTE_UP	PCSK5 YPEL2 ESRP1 HIF3A YPEL1 TENM4 LRP2 FGF12	1.47e-05	200	143	8	M5034
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HRGL3	CNTN4 GRIA1 LIX1L NECTIN3 COLEC12 FREM2 CELSR1 EFNB3 GPC4 LRP2 DNAH6 NEK11 EPHA3	1.66e-05	574	143	13	M39056
Coexpression	EIF4E_DN	SEMA4D APPBP2 ESRP1 DENND2D LOXL1 TP53BP1	1.86e-05	100	143	6	M2790
Coexpression	LI_ESTROGENE_T47D_E2_RESPONSE_UP	FLT4 NEIL2 GRIK4 FREM2 A4GALT	2.10e-05	61	143	5	M48221
Coexpression	NABA_MATRISOME	PCSK5 SEMA4D HPSE2 ADAMTS13 SVEP1 BGN SEMA4C COLEC12 FREM2 SCUBE1 RPTN LOXL1 TLL2 GPC4 FGB FGF12 DMBT1	3.71e-05	1008	143	17	MM17056
Coexpression	NABA_MATRISOME	PCSK5 SEMA4D HPSE2 ADAMTS13 SVEP1 BGN SEMA4C COLEC12 FREM2 SCUBE1 RPTN LOXL1 TLL2 GPC4 FGB FGF12 DMBT1	4.62e-05	1026	143	17	M5889
Coexpression	JARDIM_PERASSI_TRIPLE_NEGATIVE_BREAST_CANCER_MOUSE_XENOGRAFT_MELATONIN_DN	NECTIN3 TENM2 GPC4	5.54e-05	14	143	3	MM453
CoexpressionAtlas	dev gonad_e13.5_M_InterstitFLeydig_MafB_k-means-cluster#3_top-relative-expression-ranked_1000	LIX1L HPSE2 SVEP1 BGN NRXN3 IGF2R TENM4 GLI2 LOXL1 KANK4 CDH11 EPHA3 CDHR4	4.31e-07	336	142	13	gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_k3_1000
CoexpressionAtlas	dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k-means-cluster#2_top-relative-expression-ranked_1000	HPSE2 SVEP1 BGN SCUBE1 TENM4 GLI2 LOXL1 KANK4 CDH11 EPHA3 CDHR4	1.75e-06	265	142	11	gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k2_1000
CoexpressionAtlas	dev gonad_e13.5_M_InterstitFLeydig_MafB_top-relative-expression-ranked_1000	CNTN4 LIX1L HPSE2 SVEP1 BGN COLEC12 SCUBE1 NRXN3 RNASEL IGF2R TENM4 GLI2 LOXL1 GPC4 KANK4 CDH11 EPHA3 CDHR4	4.21e-06	773	142	18	gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_1000
CoexpressionAtlas	dev gonad_e13.5_M_InterstitTestis_Sma_k-means-cluster#1_top-relative-expression-ranked_500	HPSE2 SVEP1 BGN GLI2 LOXL1 KANK4 CDH11 EPHA3	1.03e-05	156	142	8	gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_k1_500
CoexpressionAtlas	dev gonad_e13.5_M_InterstitTestis_Sma_top-relative-expression-ranked_500	HPSE2 SVEP1 BGN COLEC12 SCUBE1 TENM4 GLI2 LOXL1 KANK4 CDH11 EPHA3	3.23e-05	361	142	11	gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_500
CoexpressionAtlas	dev gonad_e12.5_M_InterstitLeydig_MafB_k-means-cluster#1_top-relative-expression-ranked_1000	PCSK5 SVEP1 BGN TENM4 GLI2 SHCBP1 KANK4 CDH11 EPHA3 CDHR4	4.62e-05	310	142	10	gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_k1_1000
CoexpressionAtlas	Stromal Cells, LEC.SLN, gp38+ CD31+, Lymph Node, avg-4	NPR1 FLT4 PKHD1L1 CEMIP2 BGN STAB1 SEMA4C MLKL COLEC12 A4GALT ADGRF5 DNAH6	5.14e-05	450	142	12	GSM777063_500
CoexpressionAtlas	dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_top-relative-expression-ranked_1000	CNTN4 HPSE2 SVEP1 BGN COLEC12 SCUBE1 RNASEL TENM4 GLI2 LOXL1 GPC4 KANK4 CDH11 EPHA3 CDHR4	1.33e-04	740	142	15	gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_1000
CoexpressionAtlas	DevelopingGonad_e18.5_ovary_emap-12283_k-means-cluster#3_top-relative-expression-ranked_1000	YPEL2 ESRP1 CPEB3 SRP72 TENM4 CPEB1	1.37e-04	117	142	6	gudmap_developingGonad_e18.5_ovary_1000_k3
CoexpressionAtlas	dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_k-means-cluster#4_top-relative-expression-ranked_1000	HPSE2 BGN GLI2 LOXL1 KANK4 CDH11 EPHA3	1.39e-04	168	142	7	gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_k4_1000
CoexpressionAtlas	kidney_adult_RenalCapsule_top-relative-expression-ranked_200	NAPSA SVEP1 BGN COLEC12 LOXL1 LRP2 CDH11	1.73e-04	174	142	7	gudmap_kidney_adult_RenalCapsule_200
CoexpressionAtlas	Stromal Cells, LEC.MLN, gp38+ CD31+, Lymph Node, avg-4	NPR1 FLT4 CEMIP2 BGN STAB1 SEMA4C MLKL COLEC12 A4GALT ADGRF5 DNAH6	1.83e-04	439	142	11	GSM777059_500
CoexpressionAtlas	dev gonad_e12.5_M_InterstitLeydig_MafB_top-relative-expression-ranked_1000	PCSK5 CNTN4 KIF23 SVEP1 BGN COLEC12 SCUBE1 TENM4 GLI2 SHCBP1 GPC4 KANK4 CDH11 EPHA3 CDHR4	2.00e-04	768	142	15	gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_1000
CoexpressionAtlas	dev gonad_e13.5_M_InterstitTestis_Sma_top-relative-expression-ranked_1000	PCSK5 LIX1L HPSE2 SVEP1 BGN COLEC12 SCUBE1 IGF2R TENM4 GLI2 LOXL1 SHCBP1 KANK4 CDH11 EPHA3	2.26e-04	777	142	15	gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_1000
CoexpressionAtlas	Stromal Cells, FRC.SLN, gp38+ CD31- CD140a+, Lymph Node, avg-4	LIX1L H6PD SVEP1 BGN SEMA4C COLEC12 LOXL1 A4GALT GPC4 CDH11 EPHA3	2.49e-04	455	142	11	GSM777055_500
CoexpressionAtlas	DevelopingKidney_e15.5_Pelvic Mesenchyme_emap-8241_k-means-cluster#5_top-relative-expression-ranked_100	NRXN3 KANK4 CDH11 EPHA3	2.52e-04	46	142	4	gudmap_developingKidney_e15.5_Pelvic Mesenchyme_100_k5
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HECW1 PKHD1L1 ARFGEF3 FREM2 TENM4 LRP2 ANO3 UNC5D MYO16	9.30e-09	184	144	9	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HECW1 PKHD1L1 ARFGEF3 FREM2 TENM4 LRP2 ANO3 UNC5D MYO16	9.30e-09	184	144	9	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HECW1 PKHD1L1 ARFGEF3 FREM2 TENM4 LRP2 ANO3 UNC5D MYO16	9.30e-09	184	144	9	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	PCW_07-8.5-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	KIF23 ESRP1 HIP1R TTC6 FREM2 CELSR1 NRXN3 LRP2 ESPL1	1.35e-08	192	144	9	25378b5e4b0cea8415ff125783511fc25a56fc00
ToppCell	COVID-19-kidney-Technical/muscle_(Mes)\|kidney / Disease (COVID-19 only), tissue and cell type	HPSE2 GRIK4 CSMD2 TENM2 TTC6 NRXN3 MYO16 EPHA3	5.10e-08	159	144	8	5335cbcdeaf2bbd0268bbfe0e45c8c0d288e640d
ToppCell	3'-Distal_airway-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	GRIA1 GRIK4 SLC25A37 SVEP1 BGN LOXL1 CDH11 EPHA3	1.22e-07	178	144	8	09475e522dc1b8cf9ff1c25de5d1e3082b162948
ToppCell	3'-Distal_airway-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	GRIA1 GRIK4 SLC25A37 SVEP1 BGN LOXL1 CDH11 EPHA3	1.22e-07	178	144	8	35de8f791b0e78a6caf52ff095f05e204a59e828
ToppCell	3'-Distal_airway-Mesenchymal-Fibroblastic-fibroblastic_type_2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	GRIA1 GRIK4 SLC25A37 SVEP1 BGN LOXL1 CDH11 EPHA3	1.22e-07	178	144	8	000d25f3f13cc76cf39c46c312c6fafc2ea4f368
ToppCell	facs-Lung-nan-3m-Mesenchymal-fibroblast_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	H6PD SVEP1 BGN COLEC12 LOXL1 IRS2 CDH11 EPHA3	1.45e-07	182	144	8	c557de6ccd327c46e0a5423cd9936d78e0abae5f
ToppCell	facs-Lung-nan-3m-Mesenchymal-Alveolar_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	H6PD SVEP1 BGN COLEC12 LOXL1 IRS2 CDH11 EPHA3	1.45e-07	182	144	8	dbe4b2557cf19e0682ed446f8397d3a1153642f0
ToppCell	COVID-19-Epithelial_cells-AT2\|COVID-19 / group, cell type (main and fine annotations)	NAPSA ESRP1 TTC6 ARFGEF3 FREM2 LRP2 ADGRF5 DMBT1	1.57e-07	184	144	8	369b82f793deab672204558ae4e112cfa5aa9ccc
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NAPSA ESRP1 PPL ARFGEF3 CELSR1 NRXN3 TENM4 KANK4	1.57e-07	184	144	8	ab2f06906fc7a9931dfa0864ef506832b07fb93e
ToppCell	E16.5-samps-Mesenchymal\|E16.5-samps / Age Group, Lineage, Cell class and subclass	H6PD SVEP1 BGN COLEC12 IGF2R LOXL1 CDH11 EPHA3	1.85e-07	188	144	8	3f0f662be684e3a4c6652e636cc135a39a1d2790
ToppCell	LPS-IL1RA-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NAPSA ESRP1 ARFGEF3 CELSR1 NRXN3 TENM4 KANK4 IRS2	1.85e-07	188	144	8	4bdf8d49af0e9da349b16e3f012e1b0eec04cc4f
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CNTN4 GRIA1 SVEP1 COLEC12 GLI2 LOXL1 CDH11 MYO16	1.93e-07	189	144	8	a153b83314cf52808f685296cff8c95af3f4983d
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CNTN4 SEMA4D NPR1 PPL CELSR1 GPC4 DNAH6 UNC5D	1.93e-07	189	144	8	904b8337e2cabac2f0bf5dad5598fc429581ed81
ToppCell	PCW_07-8.5-Epithelial-Epithelial_airway-epi_intermediate_(1)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	ESRP1 TTC6 PPL ARFGEF3 FREM2 CELSR1 NRXN3 LRP2	2.01e-07	190	144	8	c95032bb3ee2b3d40fdf48016acb46d6f78a48a6
ToppCell	Control-Stromal_mesenchymal\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PCSK5 HPSE2 SVEP1 COLEC12 TENM4 GLI2 MYO16 EPHA3	2.09e-07	191	144	8	14057205ddb9b4bbc582d1358d13cf36d979a61b
ToppCell	COVID-19-lung-AT2\|lung / Disease (COVID-19 only), tissue and cell type	NAPSA ESRP1 TTC6 ARFGEF3 FREM2 LRP2 ADGRF5 DMBT1	2.09e-07	191	144	8	276455a64c2c3503d5048615762eb2ee37f0ac70
ToppCell	Children_(3_yrs)-Epithelial\|Children_(3_yrs) / Lineage, Cell type, age group and donor	NAPSA CNTN4 ESRP1 TTC6 ARFGEF3 FREM2 CELSR1 ADGRF5	2.09e-07	191	144	8	e432c6e1ae82dddf84314ce73d2b7a991630d905
ToppCell	Epithelial\|World / Lineage, Cell type, age group and donor	NAPSA CNTN4 ESRP1 TTC6 ARFGEF3 FREM2 CELSR1 ADGRF5	2.18e-07	192	144	8	499e8893afea5e6d3371e0bd018f7e86a524d669
ToppCell	nucseq-Mesenchymal-Myocytic-Myocytic_2-SCMF\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	HECW1 CSMD2 BGN TENM4 GLI2 LOXL1 CDH11 EPHA3	2.18e-07	192	144	8	67e845e513e76e820f55e2f0d15eb16f2944d05c
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	GRIA1 HPSE2 GRIK4 HIF3A SVEP1 GLI2 ANO3 CDH11	2.18e-07	192	144	8	99ce9e3c4c50cf64ebb62145f2b5420efa0db309
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	GRIA1 HPSE2 GRIK4 TENM2 SVEP1 COLEC12 GLI2 CDH11	2.36e-07	194	144	8	011e14d9ed1393275f892060e7708ffadcd0767f
ToppCell	Control-Fibroblasts-Intermediate_pathological_FB\|Control / group, cell type (main and fine annotations)	HPSE2 CSMD2 SVEP1 BGN TENM4 GLI2 CDH11 EPHA3	2.36e-07	194	144	8	03a269f75a481ea54aea8e6444605db8d6df493d
ToppCell	PCW_13-14-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	KIF23 ESRP1 HIP1R TTC6 FREM2 CELSR1 SHCBP1 ESPL1	2.36e-07	194	144	8	c197e4acbff42a9f0410b6801c2bfcf6160aefc1
ToppCell	PCW_13-14-Epithelial-Epithelial_proliferating-epi_proliferating3_(5)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	NAPSA ESRP1 TTC6 PPL ARFGEF3 FREM2 LRP2 ADGRF5	2.36e-07	194	144	8	c011cd59bb4ca4134331cba0f5d73bdbd7011d64
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	GRIA1 GRIK4 TENM2 SVEP1 COLEC12 TENM4 GLI2 CDH11	2.36e-07	194	144	8	35f132cc38ac133be01834ed0946188aa0757eb4
ToppCell	PCW_07-8.5-Epithelial\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	ESRP1 TTC6 PPL ARFGEF3 FREM2 CELSR1 NRXN3 LRP2	2.36e-07	194	144	8	f63ceedb88a9abc8644ee94adfd541e7817c1e3a
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HIF3A PKHD1L1 PPL CEMIP2 STAB1 CELSR1 IGF2R CDH11	2.55e-07	196	144	8	7d5eaed189aa6116f3799be010139fb675ec65e0
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Endothelial-endocardial_endothelial_cells\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HIF3A PKHD1L1 PPL CEMIP2 STAB1 CELSR1 IGF2R CDH11	2.55e-07	196	144	8	dbf154b3d166ffd07be717dac8d8a3350ac63e16
ToppCell	Parenchymal-10x5prime-Stromal-Fibroblastic-Fibro_peribronchial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	HECW1 HPSE2 SVEP1 BGN SCUBE1 LOXL1 CDH11 EPHA3	2.75e-07	198	144	8	300d7cc56207d77168390fa1ffcbcf76767b1b80
ToppCell	Fetal_29-31_weeks-Mesenchymal-chondrocyte-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	KIF23 TENM2 BGN COLEC12 GLI2 LOXL1 CDH11	6.24e-07	151	144	7	32d35906f4b2bd46b173e87f2dec972eb5da87b3
ToppCell	Children_(3_yrs)-Mesenchymal-chondrocyte\|Children_(3_yrs) / Lineage, Cell type, age group and donor	HPSE2 FBXO17 SVEP1 MMEL1 GLI2 CDH11 EPHA3	8.11e-07	157	144	7	f147e24f2ece82e1c54750868954d09b3c461804
ToppCell	Control\|World / group, cell type (main and fine annotations)	CNTN4 ARFGEF3 FREM2 NRXN3 LRP2 ADGRF5 DMBT1	1.28e-06	168	144	7	a3511faf2cd2c2b9c8363c8b99da3f3609c43ed6
ToppCell	356C-Fibroblasts-Fibroblast-H-\|356C / Donor, Lineage, Cell class and subclass (all cells)	FBXO17 SVEP1 BGN TENM4 LOXL1 ANO3 CDH11	1.28e-06	168	144	7	b5d74500bdac0d680ce7eb7afa0b867b8d85e6a4
ToppCell	356C-Fibroblasts-Fibroblast-H\|356C / Donor, Lineage, Cell class and subclass (all cells)	FBXO17 SVEP1 BGN TENM4 LOXL1 ANO3 CDH11	1.28e-06	168	144	7	838ce47d4958ba12047882f97925eddd02f081c7
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Endothelial-leukocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLT4 GRIA1 PKHD1L1 STAB1 CELSR1 NRXN3 DNAH6	1.68e-06	175	144	7	f6e1d7297a4dbb38e1ab4f738d91f0e62abaee69
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SVEP1 BGN GLI2 LOXL1 ANO3 CDH11 EPHA3	1.74e-06	176	144	7	9bc87cd5cda2372e1bce94c9dfd408eb1dfd8d0c
ToppCell	facs-Aorta\|facs / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPR1 FLT4 LRP2 ADGRF5 ABCG2 DNAH6 EPHA3	1.74e-06	176	144	7	0b3491451be02c18a16cdb875645be47eb867a7f
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SVEP1 BGN GLI2 LOXL1 ANO3 CDH11 EPHA3	1.74e-06	176	144	7	3f8274a7ab67f9f8a8923193763a5543cfe4defa
ToppCell	RV-11._Adipocyte\|RV / Chamber and Cluster_Paper	PCSK5 HPSE2 SVEP1 ACSL1 TENM4 KANK4 IRS2	1.88e-06	178	144	7	278bbea5cf8f0589f71675c7a3d00679391b5253
ToppCell	facs-Pancreas-Endocrine-24m-Mesenchymal\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCSK5 SVEP1 BGN MLKL COLEC12 A4GALT CDH11	1.95e-06	179	144	7	6f51a4580c06fc55cc764052c9b26f7c55660282
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CNTN4 HIF3A TTC6 ARFGEF3 FREM2 CELSR1 NRXN3	1.95e-06	179	144	7	815b959ce8721c5ded70c0ca6e318dafc691746e
ToppCell	facs-Pancreas-Endocrine-24m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCSK5 SVEP1 BGN MLKL COLEC12 A4GALT CDH11	1.95e-06	179	144	7	f14440f6ce9b4fcdd4bcb2488b949f9a0e17bc23
ToppCell	facs-Pancreas-Endocrine-24m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCSK5 SVEP1 BGN MLKL COLEC12 A4GALT CDH11	1.95e-06	179	144	7	a6ce1fa338d4905bd6afef00763ac83e916a0b37
ToppCell	E15.5-Mesenchymal-mesenchymal_fibroblast-alveolar_fibroblast_Wnt2-pa\|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	LIX1L SVEP1 BGN COLEC12 IGF2R CDH11 EPHA3	1.95e-06	179	144	7	b559f5a72cc9e3e35d05cb539b5c2e006e56e652
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CNTN4 HPSE2 SVEP1 BGN COLEC12 GLI2 CDH11	2.02e-06	180	144	7	280ff5c8f292be1b88120db5ff1788b750644856
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CNTN4 HPSE2 SVEP1 BGN COLEC12 GLI2 CDH11	2.02e-06	180	144	7	fdbd7c22044d9328a1e06e2f9a4451529d1df767
ToppCell	P28-Mesenchymal-mesenchymal_fibroblast\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	GRIA1 H6PD SVEP1 BGN COLEC12 LOXL1 CDH11	2.10e-06	181	144	7	091e7975badd1ffa463a8ec87908be20781ecfd6
ToppCell	Control-Epithelial_cells-Airway_club\|Control / group, cell type (main and fine annotations)	CNTN4 TTC6 ARFGEF3 FREM2 PTCHD1 ADGRF5 FGF12	2.10e-06	181	144	7	c755d23dd9aabc717dc73e2b3fa99a1f751e6507
ToppCell	droplet-Liver-Npc-21m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPR1 FLT4 CEMIP2 BGN STAB1 A4GALT ADGRF5	2.18e-06	182	144	7	dc55de945c6f78f32eb3a1b3520835eb8417e068
ToppCell	P28-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	GRIA1 H6PD SVEP1 BGN COLEC12 LOXL1 CDH11	2.18e-06	182	144	7	19c5e3a9d9b3728303b682102e276adfe93aa759
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	HECW1 NECTIN3 TTC6 ADGRF5 DNAH6 ANO3 EPHA3	2.18e-06	182	144	7	14a117c5e50db31ee1b2cf4df4d133451fd6d55f
ToppCell	droplet-Liver-Npc-21m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPR1 FLT4 CEMIP2 BGN STAB1 A4GALT ADGRF5	2.18e-06	182	144	7	010a7364da46101cb5068891fd7bc712ea8f13bd
ToppCell	severe-Myeloid-Neutrophils_1\|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	YPEL3 PGGHG SLC25A37 TG IGF2R IRS2 DHX34	2.26e-06	183	144	7	60a6112aa4fc4f5debda4c7e81b37539ba2e4e6e
ToppCell	PCW_05-06-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	ESRP1 TTC6 PPL ARFGEF3 FREM2 CELSR1 LRP2	2.26e-06	183	144	7	c5b10571599dc26476170b54b53f09c23e6b3117
ToppCell	P28-Mesenchymal-mesenchymal_fibroblast-alveolar_fibroblast_Wnt2-pa\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	GRIA1 H6PD SVEP1 BGN COLEC12 LOXL1 CDH11	2.34e-06	184	144	7	924400f47e6b2cdf7b0d538df75857935cf0209b
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NAPSA SEMA4D NPR1 PPL CELSR1 GPC4 UNC5D	2.34e-06	184	144	7	da06ff24ee2b2cf4715fdfce43030b2da9e0aaf8
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PCSK5 HPSE2 ADAMTS13 TENM4 GLI2 CDH11 EPHA3	2.42e-06	185	144	7	6712512100ccef456d2e2bd201d0987986c92ac9
ToppCell	COVID-19-Epithelial_cells-Airway_club\|COVID-19 / group, cell type (main and fine annotations)	CNTN4 ESRP1 TTC6 ARFGEF3 CELSR1 NRXN3 ADGRF5	2.42e-06	185	144	7	cfe6fd73d817e173fe803bc1683c291d9bcb8608
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PCSK5 HPSE2 ADAMTS13 TENM4 GPC4 CDH11 EPHA3	2.42e-06	185	144	7	3b2dfc8f4c87be516265dbecfc251276034d0efd
ToppCell	droplet-Marrow-nan-21m-Lymphocytic-immature_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	B3GNTL1 ADAMTS13 DENND2D PKHD1L1 SLC25A37 FGB	2.50e-06	119	144	6	aa3860c8d25c85baa79a0b6637bce2e269adfcc2
ToppCell	droplet-Lung-LUNG-30m-Mesenchymal-Alveolar_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GRIA1 H6PD SVEP1 BGN COLEC12 LOXL1 CDH11	2.51e-06	186	144	7	ca5e9c6531cb5d199e27509bfab1d62e3937177e
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CNTN4 ESRP1 TTC6 ARFGEF3 FREM2 CELSR1 ADGRF5	2.51e-06	186	144	7	2ea5ff14861e5f91d0e6a5767c403a24045d715c
ToppCell	droplet-Lung-LUNG-30m-Mesenchymal-fibroblast_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GRIA1 H6PD SVEP1 BGN COLEC12 LOXL1 CDH11	2.51e-06	186	144	7	1ed71b229f40a680071b14f5a7a19706e0fd14b1
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CNTN4 SEMA4D FREM2 GPC4 DNAH6 UNC5D NEK11	2.51e-06	186	144	7	5c4ffe4e4d5536ae9f8794277fe032c693e7dd56
ToppCell	droplet-Lung-nan-3m-Endothelial-Vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPR1 CEMIP2 BGN A4GALT FGB ADGRF5 ABCG2	2.60e-06	187	144	7	64dd28b23eda7dfb7fd069be2742de7bad0fd87a
ToppCell	Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)\|World / Lineage, Cell type, age group and donor	CNTN4 ESRP1 TTC6 ARFGEF3 PTCHD1 CELSR1 ADGRF5	2.60e-06	187	144	7	81cc8435b2704a9a8287b3f54acaae0f11dd4ac7
ToppCell	facs-Heart-LA-24m-Endothelial-endothelial_cell_of_endocardium\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PKHD1L1 CEMIP2 BGN STAB1 CELSR1 IGF2R CDH11	2.60e-06	187	144	7	d9943e65eedab73d141eae524e2411653a751705
ToppCell	facs-Heart-LA-24m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PKHD1L1 CEMIP2 BGN STAB1 CELSR1 IGF2R CDH11	2.60e-06	187	144	7	7b13c3b67d66f3afb410141d5471c9e78a4d8623
ToppCell	droplet-Lung-nan-3m-Endothelial-vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPR1 CEMIP2 BGN A4GALT FGB ADGRF5 ABCG2	2.60e-06	187	144	7	b535d5447bf15e95dcf025a0a455628b956fc857
ToppCell	Control-Fibroblasts-Other_FB\|Control / group, cell type (main and fine annotations)	HECW1 HPSE2 TENM2 SVEP1 TENM4 CDH11 EPHA3	2.60e-06	187	144	7	bd3739c4a52aa1ba5deffd778e113a9800f7e158
ToppCell	PCW_13-14-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	ESRP1 TTC6 PPL ARFGEF3 FREM2 CELSR1 ADGRF5	2.70e-06	188	144	7	0d86044bc340e3efb90d0022dd299873639d831c
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CNTN4 SEMA4D PPL CELSR1 GPC4 UNC5D NEK11	2.70e-06	188	144	7	63a4b25a0a6e05f80f1a6dd91b817f3cf49e6b68
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2-D231\|Adult / Lineage, Cell type, age group and donor	NAPSA TTC6 ARFGEF3 FREM2 LRP2 ADGRF5 DMBT1	2.79e-06	189	144	7	dab54a52358f66a8a9460cd6089a06c5fa7e7a5d
ToppCell	PCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	ESRP1 TTC6 ARFGEF3 FREM2 CELSR1 NRXN3 LRP2	2.79e-06	189	144	7	7659c7bbd58ee959a159294fb8d17317bbcc5681
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CNTN4 HPSE2 HIF3A SVEP1 BGN GLI2 CDH11	2.79e-06	189	144	7	c734e5693808a0333139e87bd5be2597a9252afe
ToppCell	PCW_05-06-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	ESRP1 TTC6 ARFGEF3 FREM2 CELSR1 LRP2 ESPL1	2.79e-06	189	144	7	c8b8f860aaf6c73863cd79941db6b469c830ef06
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CNTN4 HPSE2 HIF3A SVEP1 BGN GLI2 CDH11	2.89e-06	190	144	7	2e592323085ba9c019d678ac2a784462ab470ed9
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	HPSE2 SVEP1 BGN GLI2 KANK4 ANO3 CDH11	2.89e-06	190	144	7	70c86dd454afb21d4a85db56c5f369d4b342bc97
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CNTN4 HPSE2 HIF3A SVEP1 BGN GLI2 CDH11	2.89e-06	190	144	7	445952b70abffadb6ccc1ed4bbf61a88b06b73b3
ToppCell	LPS_only-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CNTN4 SVEP1 COLEC12 GLI2 LOXL1 CDH11 MYO16	2.89e-06	190	144	7	d60395739458d7f47a3350ade751fe3819500320
ToppCell	PCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_secretory_(0)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	ESRP1 TTC6 PPL ARFGEF3 FREM2 CELSR1 LRP2	2.99e-06	191	144	7	60ff989fe99d243a3d52955223680cdd1f1917a4
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CNTN4 HPSE2 HIF3A SVEP1 BGN GLI2 CDH11	2.99e-06	191	144	7	c54c420a94dc749ebc67fc64c5614663f4b9798d
ToppCell	PCW_05-06-Epithelial-Epithelial_neuroendo-epi_NE_progenitor_(7)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	ESRP1 TENM2 TTC6 ARFGEF3 FREM2 CELSR1 LRP2	2.99e-06	191	144	7	05731ece7867659c662f952812805f947032fe10
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CNTN4 HPSE2 SVEP1 BGN COLEC12 GLI2 CDH11	2.99e-06	191	144	7	1caf726bd07fdca389e678fc16304a6ef1790423
ToppCell	droplet-Heart-HEART-1m-Endothelial-endocardial_endothelial_cells\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HIF3A PKHD1L1 PPL CEMIP2 NRXN3 IGF2R CDH11	2.99e-06	191	144	7	4bfdf44d4402a42530d30c89d94946acdda4321b
ToppCell	PND01-03-samps-Mesenchymal-Matrix_fibroblast-MatrixFB-A\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	HIF3A H6PD SVEP1 BGN IGF2R LOXL1 CDH11	2.99e-06	191	144	7	e7c605b56934d1383237c1f946dbccef25d91368
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CNTN4 HPSE2 HIF3A SVEP1 BGN GLI2 CDH11	2.99e-06	191	144	7	806b94f567ea09a9f443cd4091e70cdb1253ac08
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CNTN4 HPSE2 HIF3A SVEP1 BGN GLI2 CDH11	2.99e-06	191	144	7	cb0aee740b08f7d5fdd2717ecf7429043b277ae7
ToppCell	droplet-Lung-1m-Mesenchymal-fibroblast-alveolar_fibroblast\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GRIA1 H6PD SVEP1 BGN COLEC12 LOXL1 CDH11	2.99e-06	191	144	7	d04e6292fef189b8d8ed0f4b0c310b2b250fd30e
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CNTN4 HPSE2 SVEP1 BGN COLEC12 GLI2 CDH11	2.99e-06	191	144	7	3d60c46bced2984c27a1fcf2910bc38b31fb0148
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	GRIA1 GRIK4 HIF3A SVEP1 GLI2 ANO3 CDH11	2.99e-06	191	144	7	6688cee34beee4f151ac17fccbc9c26a9aad72e1
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CNTN4 HPSE2 SVEP1 BGN COLEC12 GLI2 CDH11	3.10e-06	192	144	7	4022f208eb5db760abd0aac782a25e8ab63efc64
ToppCell	facs-Heart-LA-3m-Endothelial-endothelial_cell_of_endocardium\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DENND2D PKHD1L1 CEMIP2 STAB1 CELSR1 IGF2R CDH11	3.10e-06	192	144	7	14a816ef116aa992f86edab411f043cf7d07fe04
ToppCell	PND14-Mesenchymal-Mesenchymal_structural\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GRIA1 H6PD SVEP1 BGN COLEC12 LOXL1 CDH11	3.10e-06	192	144	7	25492568f9cbe097b7bb1db50d8b817c80ea87d7
ToppCell	facs-Pancreas-Exocrine-3m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SVEP1 BGN COLEC12 GLI2 LOXL1 CDH11 EPHA3	3.10e-06	192	144	7	8937a59f6bbe07f671bdabbd3707dc9c17a14cd9
ToppCell	Epithelial-alveolar_epithelial_cell_type_2\|World / Lineage, Cell type, age group and donor	NAPSA ESRP1 ARFGEF3 FREM2 LRP2 ADGRF5 DMBT1	3.10e-06	192	144	7	58c3737be7acce39fd2b91d70d6d7b2bbaa4f710
ToppCell	facs-Pancreas-Exocrine-3m-Mesenchymal\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SVEP1 BGN COLEC12 GLI2 LOXL1 CDH11 EPHA3	3.10e-06	192	144	7	e4a7f2673f801b008ca67291db2fb2b9fd2955b8
Drug	Liothyronine [6893-02-3]; Up 200; 6.2uM; HL60; HT_HG-U133A	NPR1 PGGHG HIF3A STAB1 NRXN3 EFNB3 GPC4 LRP2 NUP188 NEK11	5.31e-07	200	142	10	2984_UP
Drug	Ketanserin tartrate hydrate [83846-83-7]; Down 200; 7uM; PC3; HT_HG-U133A	SEMA4D H6PD IGF1R IGF2R PSME4 SNX27 IRS2 CPEB1 ATPAF2	2.99e-06	189	142	9	6649_DN
Drug	Cimetidine [51481-61-9]; Down 200; 15.8uM; MCF7; HT_HG-U133A	TRAF3 ZNF573 H6PD ARHGAP35 LRP2 LRP3 IRS2 HERC6 DHX34	3.55e-06	193	142	9	1464_DN
Drug	Spironolactone [52-01-7]; Up 200; 9.6uM; PC3; HT_HG-U133A	SEMA4D FLT4 HECW1 OGFR COLEC12 CELSR3 FGB NUP188 ATPAF2	4.03e-06	196	142	9	5781_UP
Drug	estradiol, USP; Up 200; 0.1uM; MCF7; HT_HG-U133A	SEMA4D OGFR H6PD CEMIP2 VPS13D GLI2 LOXL1 A4GALT GPC4	4.03e-06	196	142	9	6928_UP
Drug	Pempidine tartrate [546-48-5]; Up 200; 13uM; MCF7; HT_HG-U133A	NPR1 ARHGAP35 SEMA4C VPS13D IGF1R A4GALT TNKS NUP188 ATPAF2	4.20e-06	197	142	9	3832_UP
Drug	retinoic acid; Up 200; 1uM; MCF7; HT_HG-U133A_EA	FLT4 CLIP1 RNASEL MID1IP1 PSME4 FZD5 LOXL1 IRS2	1.18e-05	170	142	8	849_UP
Drug	Methotrexate [59-05-2]; Down 200; 8.8uM; MCF7; HT_HG-U133A	KIF23 NECTIN3 LBR RNASEL MID1IP1 IRS2 ESPL1 DHX34	1.85e-05	181	142	8	5419_DN
Drug	wortmannin from Penicillium funiculosum; Up 200; 0.01uM; MCF7; HT_HG-U133A_EA	CPEB3 ARHGAP35 YPEL1 BGN EFNB3 A4GALT LRP2 IRS2	2.43e-05	188	142	8	1023_UP
Drug	Resveratrol [501-36-0]; Down 200; 17.6uM; MCF7; HT_HG-U133A	FLT4 OGFR ATP9B CLIP1 SEMA4C ESPL1 DHX34 EPHA3	2.83e-05	192	142	8	2865_DN
Drug	haloperidol; Up 200; 10uM; MCF7; HT_HG-U133A_EA	ZNF573 B3GNTL1 OGFR HIP1R H6PD VPS13D A4GALT DHX34	3.05e-05	194	142	8	1024_UP
Drug	Atropine sulfate monohydrate [5908-99-6]; Up 200; 5.8uM; MCF7; HT_HG-U133A	FLT4 NECTIN3 SLC25A37 BGN VPS13D EFNB3 TNKS IRS2	3.16e-05	195	142	8	7219_UP
Drug	Lincomycin hydrochloride [859-18-7]; Up 200; 9uM; MCF7; HT_HG-U133A	FLT4 NECTIN3 VPS13D RNASEL EFNB3 CELSR3 IRS2 EPHA3	3.40e-05	197	142	8	7411_UP
Drug	Ambroxol hydrochloride [23828-92-4]; Up 200; 9.6uM; PC3; HT_HG-U133A	ZNF573 FBXO11 ATP9B HIF3A DENND2D NECTIN3 SEMA4C ADGRF5	3.40e-05	197	142	8	6719_UP
Drug	Isoxsuprine hydrochloride [579-56-6]; Down 200; 11.8uM; MCF7; HT_HG-U133A	SEMA4D H6PD SLC25A37 VPS13D RNASEL EFNB3 GPC4 LRP2	3.40e-05	197	142	8	1485_DN
Drug	Indoprofen [31842-01-0]; Up 200; 14.2uM; HL60; HT_HG-U133A	PCSK5 OGFR HIP1R HIF3A A4GALT GPC4 TNKS DHX34	3.40e-05	197	142	8	3007_UP
Drug	Corynanthine hydrochloride [66634-44-4]; Up 200; 10.2uM; MCF7; HT_HG-U133A	NPR1 CPEB3 ADAMTS13 NECTIN3 VPS13D EFNB3 FGB ATPAF2	3.52e-05	198	142	8	4811_UP
Drug	chlorpromazine hydrochloride; Down 200; 1uM; MCF7; HT_HG-U133A_EA	OGFR SLC25A37 SEMA4C MID1IP1 PSME4 RRN3 LRP3 TP53BP1	3.65e-05	199	142	8	1055_DN
Drug	Vitamin K2 [11032-49-8]; Down 200; 9uM; PC3; HT_HG-U133A	SEMA4D MAN2C1 H6PD SLC25A37 SEMA4C NRXN3 HELZ ATPAF2	3.65e-05	199	142	8	4534_DN
Drug	Noscapine [128-62-1]; Up 200; 9.6uM; PC3; HT_HG-U133A	FLT4 B3GNTL1 SVEP1 BGN EFNB3 CELSR3 LRP2 ATPAF2	3.78e-05	200	142	8	5851_UP
Drug	Piribedil hydrochloride [78213-63-5]; Up 200; 12uM; PC3; HT_HG-U133A	FLT4 OGFR ARHGAP35 EFNB3 A4GALT IFT122 CPEB1 ATPAF2	3.78e-05	200	142	8	6333_UP
Disease	response to aripiprazole, response to antipsychotic drug	CNTN4 TENM2	2.17e-05	2	138	2	EFO_0009261, GO_0097332
Disease	waist-hip ratio	PCSK5 APPBP2 TRAF3 CPEB3 HIP1R H6PD PPL STAB1 IGF1R NRXN3 LOXL1 ADGRF5 IFT122 POLD3 ANO3 ZMYM4 EPHA3	6.16e-05	1226	138	17	EFO_0004343
Disease	Clear-cell metastatic renal cell carcinoma	FLT4 DNMT1	1.29e-04	4	138	2	C2931852
Disease	attempted suicide	PCSK5 TRAF3 GRIK4 LRP2 ANO3 CDH11	1.97e-04	178	138	6	EFO_0004321
Disease	Milroy Disease	FLT4 CELSR1	2.15e-04	5	138	2	C1704423
Disease	cortical thickness	SEMA4D ARHGAP35 TENM2 STAB1 TG CHMP7 VPS13D SCUBE1 CELSR1 IGF1R UMODL1 CDH11 MYO16 EPHA3 CPEB1	2.32e-04	1113	138	15	EFO_0004840
Disease	toxic encephalopathy (is_implicated_in)	IGF1R ABCG2	3.22e-04	6	138	2	DOID:3602 (is_implicated_in)
Disease	lifestyle measurement, anxiety disorder measurement	CSMD2 NPLOC4 TTC6 CEMIP2 UNC5D	4.74e-04	137	138	5	EFO_0007795, EFO_0010724
Disease	hyperuricemia	IGF1R LRP2 ABCG2	4.93e-04	33	138	3	EFO_0009104
Disease	pack-years measurement, systolic blood pressure	CNTN4 NRXN3 LRP2	5.39e-04	34	138	3	EFO_0006335, EFO_0006526
Disease	coronary aneurysm	CSMD2 TTC6 NRXN3	5.87e-04	35	138	3	EFO_1000881
Disease	urate measurement, bone density	CNTN4 B3GNTL1 DHX33 CLIP1 TENM2 PPL TG GLI2 DMBT1 MYO16	6.88e-04	619	138	10	EFO_0003923, EFO_0004531
Disease	visceral heterotaxy (implicated_via_orthology)	PCSK5 ANKS6 PSME4	6.92e-04	37	138	3	DOID:0050545 (implicated_via_orthology)
Disease	Kidney Diseases	PCSK5 NPR1 LRP2 IFT122	7.88e-04	88	138	4	C0022658
Disease	thioredoxin domain-containing protein 12 measurement	IQCF1 CELSR3 CDHR4	8.09e-04	39	138	3	EFO_0008298
Disease	body surface area	PCSK5 TRAF3 GRIA1 H6PD SLC25A37 IGF1R NRXN3 GLI2 POLD3 DNMT1	9.18e-04	643	138	10	EFO_0022196
Disease	social interaction measurement	TENM2 COLEC12 KANK4 TNKS	1.01e-03	94	138	4	EFO_0009592
Disease	Liver Cirrhosis, Experimental	YPEL3 PFN1 CEMIP2 BGN ACSL1 COLEC12 RNASEL IGF2R MID1IP1 ANO6 SHCBP1	1.06e-03	774	138	11	C0023893
Disease	HbA1c measurement	B3GNTL1 YPEL2 ADAMTS13 DENND2D SLC25A37 TTC6 EIF2B4 A4GALT ABCG2 UNC5D	1.32e-03	675	138	10	EFO_0004541
Disease	autoimmune thyroiditis (is_implicated_in)	TG LRP2	1.39e-03	12	138	2	DOID:7188 (is_implicated_in)
Disease	cortical surface area measurement	SEMA4D NECTIN3 TENM2 NPLOC4 SVEP1 TG CHMP7 COLEC12 SCUBE1 CELSR1 TNKS POLD3 CDH11 MYO16 EPHA3	1.61e-03	1345	138	15	EFO_0010736
Disease	amyotrophic lateral sclerosis (biomarker_via_orthology)	IGF1R IGF2R	1.64e-03	13	138	2	DOID:332 (biomarker_via_orthology)
Disease	colon carcinoma (is_marker_for)	KMT2D IGF2R	1.64e-03	13	138	2	DOID:1520 (is_marker_for)
Disease	Congenital Hypothyroidism	TG IGSF1	1.64e-03	13	138	2	C0010308
Disease	Bipolar Disorder	CNTN4 HIP1R GRIA1 GRIK4 STAB1 TENM4 TLL2 DNMT1	1.87e-03	477	138	8	C0005586
Disease	nephroblastoma (is_implicated_in)	IGF1R IGF2R	1.90e-03	14	138	2	DOID:2154 (is_implicated_in)
Disease	lifestyle measurement, alcohol consumption measurement	CSMD2 CEMIP2 DHX34 UNC5D	2.12e-03	115	138	4	EFO_0007878, EFO_0010724
Disease	amyotrophic lateral sclerosis, age at onset	PCSK5 NRXN3	2.19e-03	15	138	2	EFO_0004847, MONDO_0004976
Disease	Yu-Zhi constitution type	RRN3P2 FREM2	2.19e-03	15	138	2	EFO_0007638
Disease	Graves' disease (is_marker_for)	TG IGF1R	2.19e-03	15	138	2	DOID:12361 (is_marker_for)
Disease	Diffuse Large B-Cell Lymphoma	FBXO11 KMT2D ABCG2	2.20e-03	55	138	3	C0079744
Disease	hypertrophic cardiomyopathy (is_marker_for)	IGF1R DNMT1	2.82e-03	17	138	2	DOID:11984 (is_marker_for)
Disease	chronotype measurement	CNTN4 SEMA4D CPEB3 CLIP1 TENM2 CEMIP2 KMT2D NRXN3 RNASEL UNC5D MYO16	2.95e-03	882	138	11	EFO_0008328
Disease	Congenital hernia of foramen of Morgagni	IGF1R IGF2R	3.52e-03	19	138	2	C0265699
Disease	Congenital hernia of foramen of Bochdalek	IGF1R IGF2R	3.52e-03	19	138	2	C0265700
Disease	non-alcoholic fatty liver disease (biomarker_via_orthology)	ADAMTS13 IGF1R IRS2	3.54e-03	65	138	3	DOID:0080208 (biomarker_via_orthology)
Disease	breast carcinoma (is_marker_for)	KMT2D IGF2R ABCG2	3.69e-03	66	138	3	DOID:3459 (is_marker_for)
Disease	maximal midexpiratory flow rate	MED12L MYO16	3.90e-03	20	138	2	EFO_0004313
Disease	cup-to-disc ratio measurement	ARHGAP35 NPLOC4 IGF1R LOXL1 HELZ MYO16 EPHA3	4.21e-03	430	138	7	EFO_0006939
Disease	Congenital diaphragmatic hernia	IGF1R IGF2R	4.30e-03	21	138	2	C0235833

Protein segments in the cluster

Peptide	Gene	Start	Entry
GYTGQGVFSNVVRAR	PRPF4B	691	Q13523
SNVVGYDRNNTGKGV	UMODL1	616	Q5DID0
ESGYGNASKRFQVVS	CATSPERG	421	Q6ZRH7
QGYQVGSTVLFRCQK	CSMD2	3146	Q7Z408
FGVLQAGQYGVAQTR	DNMT1	1296	P26358
NVLGTQSRYVLNGAF	A4GALT	206	Q9NPC4
TLYEGFQRGIQVSNN	ACSL1	91	P33121
VAYVLRTGFNTSQGK	ATP13A1	411	Q9HD20
AIYFGLKNDSTGIQN	ABCG2	411	Q9UNQ0
RGKNVARGQLTFYAQ	CNTN4	301	Q8IWV2
YQAALDIRQSVFGGK	APPBP2	311	Q92624
TYQLTGGNTRNRFAL	CELSR1	721	Q9NYQ6
ENGAFRVVLNYNGTS	NPR1	416	P16066
SYSIVGGNSQNRFIL	CDHR4	586	A6H8M9
SEGFLKAQASLRGQY	ADAMTS13	1391	Q76LX8
GIRKLINNGSYIAAF	ANO3	326	Q9BYT9
AYNTGVKEILNFFQG	ESRP1	641	Q6NXG1
RGFIKGQYRVTANQL	IQCF1	166	Q8N6M8
CGYVIFRGANSQKNA	LBR	496	Q14739
GINRLVNSGIYKAAF	ANO6	231	Q4KMQ2
GTYGNRQVLKLDTNG	DTD2	146	Q96FN9
GTTNAFLQYKQNGGL	KCND1	441	Q9NSA2
HRQKLQGFVVGYNGS	IFT122	586	Q9HBG6
GGNTAFNQQVRARIY	MED12L	411	Q86YW9
NILTNRYKQEIGFGN	MID1IP1	166	Q9NPA3
RKRFYQNVSITQGEG	ATPAF2	46	Q8N5M1
LDQRYFSGLGNIIKN	NEIL2	221	Q969S2
IQKRFGNNQIYTFIG	MYO16	421	Q9Y6X6
RYLFAVTGNGLANQG	GPC4	431	O75487
LDYKNRGVNGSHRGQ	HECW1	126	Q76N89
GRNSYKRSAALGQFV	ATP9B	921	O43861
VEDGGGNKLTYQNFR	FREM2	1751	Q5SZK8
RNGAQQGRLSVGSVY	LOXL1	346	Q08397
KRNNSRLGNGVLYAS	IGF1R	961	P08069
NKYQISVNKYRGTAG	FGB	366	P02675
NRIASKYGFINIGQI	PCSK5	51	Q92824
LISRGYSYTLQKNNG	PPL	416	O60437
YNNISLGIAFFGNKI	PGLYRP3	111	Q96LB9
GVKRAYYNGISLFNN	BGN	326	P21810
VQSFGYKRFGIQEGT	COLEC12	11	Q5KU26
NNGFSVYINRNKTGE	NPLOC4	41	Q8TAT6
KVFTFGDNRSGQLGY	HERC6	256	Q8IVU3
GKYHVVRFTRNGGNA	NRXN3	1176	Q9Y4C0
ARRYVLQQKLGSGSF	NEK11	26	Q8NG66
SGQAQGFRLSYIRGK	LRP3	146	O75074
RSFAKHTQGYGRVNV	LIX1L	86	Q8IVB5
YQQILSQQRGLGSAF	GLI2	296	P10070
RQYQLLFTQGSGENK	HM13	136	Q8TCT9
DRIYFTQNLASGVGQ	LRP2	2431	P98164
RVSVSGIFYQGNKLN	PGGHG	621	Q32M88
GRAVNGSQLGKDYIQ	HPSE2	271	Q8WWQ2
NGGSNRKVREAYLQF	MMEL1	266	Q495T6
AQAISRFAYQKISNG	EIF2B4	316	Q9UI10
YAQNGQLFGRFKLTE	HELZ	501	P42694
NFLVTQGYQVKLAGF	MLKL	336	Q8NB16
GANFTLYRGGQVVQL	HIDE1	46	A8MVS5
GISTVNRGNYSYLKQ	MGAT4D	136	A6NG13
QVSHVFTNFGKGIRY	FBXO17	231	Q96EF6
RETSAGFQNGLNYIA	IRS2	1241	Q9Y4H2
YVGNQNLNSLRGFVL	FZD5	391	Q13467
GFLTGTLQNHARKYN	DNAH6	3996	Q9C0G6
SGRGAATQQEFYAKN	HIP1R	851	O75146
QLRDDGVYGGSSKQQ	ESPL1	376	Q14674
GVYGGSSKQQQSFLQ	ESPL1	381	Q14674
FVINNVEGKGIGNYS	IGSF1	1211	Q8N6C5
KGAGRVAFSNQQSYI	CPEB3	591	Q8NE35
GRGQFIENKIYANNF	FBXO11	511	Q86XK2
VFNAYQAGVGALKLS	CHMP7	321	Q8WUX9
KVSGIGGAANLYRQS	ARFGEF3	1796	Q5TH69
AGVYARRGGFSRQKQ	CDH11	551	P55287
TLLNIYRTFKNLGGN	DHX33	561	Q9H6R0
GQNYSNHSKRGAFVQ	AKNAD1	696	Q5T1N1
NQGADVTLRAKNGYT	ANKS6	381	Q68DC2
FQVTFGYLQRQNGSL	CEMIP2	1081	Q9UHN6
VFQIRARTAAGYGTN	EPHA3	506	P29320
GLGKDNQRSFQALYT	MAN2C1	201	Q9NTJ4
KNLQFVGVNGGYETT	KANK4	661	Q5T7N3
IGSGRVTFNNQRSYL	CPEB1	471	Q9BZB8
YQITGGNTRNRFAIS	CELSR3	791	Q9NYQ7
GNVQFNEKGRRTNYT	GRIA1	351	P42261
GHIEFNSKGQRSNYA	GRIK4	361	Q16099
RGLQRGSAVVGQYQS	H6PD	301	O95479
IEVNSGYRINLGFSN	DMBT1	1796	Q9UGM3
AKRVGFESLSQYGSQ	DHX34	221	Q14147
NSANKRFQAEGGYVL	EFNB3	36	Q15768
RKSIGRQQFYVQVSG	SCUBE1	586	Q8IWY4
IGKNDGSVAGVRYFQ	CLIP1	96	P30622
ASYIKREANGQGHFQ	DENND2D	391	Q9H6A0
YKTRGGGQSVQFTDI	KIF23	881	Q02241
GTGTVGRAQNYQKRF	OGFR	186	Q9NZT2
IENLLGYQSGKTGFR	OR4A8	296	P0C604
SATGGGNKVYSFQNR	ORC2	86	Q13416
RLSYVGNNFGTGALK	POLR1E	66	Q9GZS1
KGIVTRLFSQQGYFL	FGF12	71	P61328
NSSQGYNVSGIGKIF	IGF2R	951	P11717
QAAGNYIGSFLARAK	RRN3	401	Q9NYV6
AQKVEYSGGLGRQFF	TAS2R41	71	P59536
RSSFYVNGLTLGGQK	PFN1	56	P07737
GRYGRVIVTSFQKAN	PTCHD1	91	Q96NR3
GKYHVVRFTRNGGNA	NRXN3	171	Q9HDB5
KGQAVTGQYRFLARS	HIF3A	296	Q9Y2N7
QLNGLAGYFKGIQAR	SLC25A37	291	Q9NYZ2
RGNFYQNTVGDLLKF	RNASEL	651	Q05823
VNVSYFFNGRLAGLQ	TENM2	1891	Q9NT68
FGYQKNSNIQAKGVR	SHCBP1	311	Q8NEM2
KKGNRFVYAGSNSGV	SEMA4D	481	Q92854
GKANRQVSITGFFQR	POLD3	451	Q15054
GRNSNANGYVRLQLG	SEMA4C	781	Q9C0C4
YGQNGDFTRALKTVN	SRP72	21	O76094
GTYTKGAFQQAAQIL	SVEP1	166	Q4LDE5
ASAGIGYGRNINEKQ	ARHGAP35	736	Q9NRY4
RGVGYAKNQAVAQSS	B3GNTL1	91	Q67FW5
RRFNNLFGKTGTYNV	ADGRF5	1311	Q8IZF2
QRATLTYNKGGSRFV	FYTTD1	301	Q96QD9
LISKSFQGSQGRAYL	YPEL1	36	O60688
YNGRAKGRQFGSKCN	SPRYD3	126	Q8NCJ5
RYGCVFQGTNQQIKA	TRAF3	236	Q13114
LYQTKDGSQRGGIFS	ZNF136	71	P52737
GKNFRSGYQLTVHQR	ZNF573	196	Q86YE8
GKAFNRGSYLTQHQR	ZNF519	326	Q8TB69
IKARISFGYNLQAQG	TTC6	281	Q86TZ1
QKAVKFLANFYINGG	STPG3	6	Q8N7X2
GNAGGIFNRYNVIRI	TNKS	1136	O95271
GSYVCKANNGIQRFR	FLT4	306	P35916
AKNIQYFGAGTRLSV	TRBJ2-4	1	A0A0A0MT87
YVIGGNFTGSQRAIF	TLL2	166	Q9Y6L7
GGTAIQLNVFQYLTR	NUP188	346	Q5SRE5
QAAGNYIGSFLARAK	RRN3P1	26	Q2M238
QQVLSTGRVQGYDGF	TENM4	2726	Q6N022
IVKSESGYGFNVRGQ	SNX27	46	Q96L92
RNVTAAAQGFGYKIF	STAB1	1726	Q9NY15
FNKQYTESQLRAGAG	TP53BP1	1771	Q12888
LQNNVVAGFGRAGYR	PKHD1L1	3421	Q86WI1
RQAAGNYIGSFLARA	RRN3P2	286	A6NIE6
TGGFQTFNFKTVRQG	UNC5D	421	Q6UXZ4
RQGVTQQQFKGALYC	PSME4	1016	Q14997
LISKSFQGSQGRAYL	YPEL2	36	Q96QA6
YAQRNAKGGVVAGNV	TTC37	1206	Q6PGP7
IQGQNKYFQGTEGTR	RPTN	591	Q6XPR3
KTAFYQALQNSLGGE	TG	2536	P01266
QNSNASVYFREIGGL	TERB1	46	Q8NA31
KQQGNFKATYRAGIA	TTC9B	166	Q8N6N2
GQTAYQRKGSTQLFC	ZMYM4	351	Q5VZL5
LISKSFQGSQGRAYL	YPEL3	36	P61236
NGRYISVLKVFGTNA	VPS13D	971	Q5THJ4
VNSRQLVGGSQAFYQ	KMT2D	2786	O14686
YSLGGNRRISFNVAG	KRT74	51	Q7RTS7
QANGTKFAIQYGTGR	NAPSA	131	O96009
FSVQGEYQGRVLFKN	NECTIN3	111	Q9NQS3