Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	cytoskeletal anchor activity	JUP ANK2 ANK3	1.27e-04	24	82	3	GO:0008093
GeneOntologyMolecularFunction	nucleoside-triphosphatase regulator activity	STARD13 RAPGEF6 LLGL2 TRIO SYDE2 SH3BP1 IQSEC1 ARHGAP9 RIC1	2.31e-04	507	82	9	GO:0060589
GeneOntologyMolecularFunction	GTPase regulator activity	STARD13 RAPGEF6 LLGL2 TRIO SYDE2 SH3BP1 IQSEC1 ARHGAP9 RIC1	2.31e-04	507	82	9	GO:0030695
GeneOntologyBiologicalProcess	action potential	JUP CACNB4 DRD1 NUP155 ANK2 ANK3 CNTNAP2 CHRNA5	1.36e-06	201	82	8	GO:0001508
GeneOntologyBiologicalProcess	transmission of nerve impulse	CACNB4 DRD1 ANK3 PAFAH1B1 CNTNAP2 CHRNA5	5.61e-06	112	82	6	GO:0019226
GeneOntologyBiologicalProcess	regulation of small GTPase mediated signal transduction	STARD13 OGT TRIO SYDE2 SH3BP1 IQSEC1 KIF14 ARHGAP9 NOTCH2	6.96e-06	333	82	9	GO:0051056
GeneOntologyBiologicalProcess	regulation of action potential	JUP ANK2 ANK3 CNTNAP2 CHRNA5	1.77e-05	81	82	5	GO:0098900
GeneOntologyBiologicalProcess	microtubule cytoskeleton organization	ABRAXAS2 FSIP2 DNAAF5 LLGL2 AUNIP ANK3 MARK1 PAFAH1B1 NAV3 KIF14 WDR62 PCNT	2.64e-05	720	82	12	GO:0000226
GeneOntologyBiologicalProcess	intracellular protein transport	JUP TLK1 DRD1 NUP155 TECPR2 VPS33A BCL3 TIMM44 SIX2 RIC1 TRIM23 PCNT	3.45e-05	740	82	12	GO:0006886
GeneOntologyBiologicalProcess	regulation of nervous system development	CLSTN3 BMPR2 RNF6 FEZF1 PAFAH1B1 IQSEC1 KIF14 MAP3K13 SPEN NOTCH2 WDR62	3.60e-05	625	82	11	GO:0051960
GeneOntologyBiologicalProcess	interneuron migration	DRD1 FEZF1 PAFAH1B1	3.96e-05	17	82	3	GO:1904936
GeneOntologyBiologicalProcess	small GTPase-mediated signal transduction	STARD13 RAPGEF6 OGT TRIO SYDE2 SH3BP1 IQSEC1 KIF14 ARHGAP9 NOTCH2	5.32e-05	538	82	10	GO:0007264
GeneOntologyBiologicalProcess	osteoclast development	PAFAH1B1 LRRK1 NOTCH2	8.83e-05	22	82	3	GO:0036035
GeneOntologyBiologicalProcess	bone cell development	PAFAH1B1 LRRK1 NOTCH2	8.83e-05	22	82	3	GO:0098751
GeneOntologyBiologicalProcess	plasma membrane bounded cell projection morphogenesis	CLSTN3 BMPR2 ANK3 RNF6 TRIO FEZF1 PAFAH1B1 TET1 CNTNAP2 CD44 MAP3K13 NOTCH2	9.12e-05	819	82	12	GO:0120039
GeneOntologyBiologicalProcess	cell projection morphogenesis	CLSTN3 BMPR2 ANK3 RNF6 TRIO FEZF1 PAFAH1B1 TET1 CNTNAP2 CD44 MAP3K13 NOTCH2	9.89e-05	826	82	12	GO:0048858
GeneOntologyBiologicalProcess	neuronal action potential	DRD1 ANK3 CNTNAP2 CHRNA5	1.16e-04	63	82	4	GO:0019228
GeneOntologyBiologicalProcess	atrial septum development	BMPR2 ANK2 NOTCH2	1.31e-04	25	82	3	GO:0003283
GeneOntologyBiologicalProcess	adult behavior	CACNB4 DRD1 PAFAH1B1 CNTNAP2 PUM1 CHRNA5	1.59e-04	203	82	6	GO:0030534
GeneOntologyBiologicalProcess	negative regulation of multicellular organismal process	STARD13 JUP CLSTN3 BMPR2 DRD1 USF3 OGT RNF6 MARK1 TET1 CNTNAP2 CD44 NAV3 MUC16 BCL3 MEPE	2.19e-04	1488	82	16	GO:0051241
GeneOntologyBiologicalProcess	neuron migration	DRD1 FEZF1 MARK1 PAFAH1B1 WDR62 PCNT	2.33e-04	218	82	6	GO:0001764
GeneOntologyBiologicalProcess	positive regulation of nervous system development	CLSTN3 BMPR2 PAFAH1B1 IQSEC1 MAP3K13 SPEN NOTCH2 WDR62	2.56e-04	418	82	8	GO:0051962
GeneOntologyBiologicalProcess	microtubule-based process	ABRAXAS2 FSIP2 DNAAF5 BORCS8 LLGL2 AUNIP ANK3 MARK1 PAFAH1B1 NAV3 KIF14 WDR62 PCNT	2.61e-04	1058	82	13	GO:0007017
GeneOntologyBiologicalProcess	neuron projection morphogenesis	CLSTN3 BMPR2 ANK3 RNF6 TRIO FEZF1 PAFAH1B1 TET1 CNTNAP2 MAP3K13 NOTCH2	3.24e-04	802	82	11	GO:0048812
GeneOntologyBiologicalProcess	neural precursor cell proliferation	PAFAH1B1 CNTNAP2 KIF14 NOTCH2 WDR62 PCNT	3.33e-04	233	82	6	GO:0061351
GeneOntologyBiologicalProcess	telencephalon development	DMXL2 DRD1 FEZF1 PAFAH1B1 KIF14 WDR62 PCNT	3.55e-04	332	82	7	GO:0021537
GeneOntologyBiologicalProcess	cardiac muscle cell action potential	JUP NUP155 ANK2 ANK3	4.02e-04	87	82	4	GO:0086001
GeneOntologyBiologicalProcess	maintenance of cell number	OGT TET1 MECOM BCL9 SIX2 WDR62	4.08e-04	242	82	6	GO:0098727
GeneOntologyBiologicalProcess	axonogenesis	BMPR2 ANK3 RNF6 TRIO FEZF1 PAFAH1B1 CNTNAP2 MAP3K13 NOTCH2	4.09e-04	566	82	9	GO:0007409
GeneOntologyBiologicalProcess	cell junction assembly	JUP CLSTN3 DRD1 OGT ANK2 MARK1 CNTNAP2 SH3BP1 IQSEC1	4.25e-04	569	82	9	GO:0034329
GeneOntologyBiologicalProcess	cell junction organization	JUP CACNB4 CLSTN3 DRD1 OGT ANK2 ANK3 MARK1 PAFAH1B1 CNTNAP2 SH3BP1 IQSEC1	4.50e-04	974	82	12	GO:0034330
GeneOntologyBiologicalProcess	cell cycle process	ABRAXAS2 CACNB4 TLK1 LLGL2 AUNIP ANK3 PAFAH1B1 KIF14 PUM1 NCAPH TRRAP MN1 WDR62 RFWD3 PCNT	5.01e-04	1441	82	15	GO:0022402
GeneOntologyBiologicalProcess	neuron projection development	CLSTN3 BMPR2 ANK3 RNF6 TRIO FEZF1 MARK1 PAFAH1B1 TET1 CNTNAP2 CD44 IQSEC1 MAP3K13 NOTCH2	5.04e-04	1285	82	14	GO:0031175
GeneOntologyBiologicalProcess	neuron development	CLSTN3 BMPR2 DRD1 ANK3 RNF6 TRIO FEZF1 MARK1 PAFAH1B1 TET1 CNTNAP2 CD44 IQSEC1 MAP3K13 NOTCH2	5.87e-04	1463	82	15	GO:0048666
GeneOntologyBiologicalProcess	protein localization to nucleus	JUP CACNB4 DRD1 OGT NUP155 BCL3 SIX2	5.95e-04	362	82	7	GO:0034504
GeneOntologyBiologicalProcess	postsynaptic modulation of chemical synaptic transmission	DRD1 TRIO IQSEC1	6.22e-04	42	82	3	GO:0099170
GeneOntologyBiologicalProcess	cardiac atrium development	BMPR2 ANK2 NOTCH2	6.22e-04	42	82	3	GO:0003230
GeneOntologyBiologicalProcess	marginal zone B cell differentiation	BCL3 NOTCH2	6.88e-04	10	82	2	GO:0002315
GeneOntologyBiologicalProcess	forebrain development	DMXL2 DRD1 FEZF1 PAFAH1B1 KIF14 MECOM WDR62 PCNT	7.23e-04	489	82	8	GO:0030900
GeneOntologyBiologicalProcess	intracellular transport	BORCS8 JUP TLK1 DRD1 NUP155 ANK3 TECPR2 PAFAH1B1 VPS33A BCL3 TIMM44 SIX2 RIC1 TRIM23 PCNT	7.40e-04	1496	82	15	GO:0046907
GeneOntologyBiologicalProcess	cell morphogenesis involved in neuron differentiation	BMPR2 ANK3 RNF6 TRIO FEZF1 PAFAH1B1 TET1 CNTNAP2 MAP3K13 NOTCH2	7.51e-04	748	82	10	GO:0048667
GeneOntologyBiologicalProcess	regulation of axon extension	BMPR2 RNF6 PAFAH1B1 MAP3K13	7.89e-04	104	82	4	GO:0030516
GeneOntologyBiologicalProcess	cell morphogenesis	CLSTN3 BMPR2 ANK3 RNF6 TRIO FEZF1 PAFAH1B1 TET1 VPS33A CNTNAP2 CD44 MAP3K13 NOTCH2	8.22e-04	1194	82	13	GO:0000902
GeneOntologyBiologicalProcess	protein localization to axon	ANK3 CNTNAP2	8.39e-04	11	82	2	GO:0099612
GeneOntologyCellularComponent	cerebellar granule cell to Purkinje cell synapse	OGT CNTNAP2	3.08e-04	7	81	2	GO:0150048
GeneOntologyCellularComponent	histone deacetylase complex	OGT TET1 MECOM TRRAP	3.34e-04	85	81	4	GO:0000118
GeneOntologyCellularComponent	asymmetric synapse	DLGAP1 CLSTN3 BMPR2 OGT ANK2 ANK3 CNTNAP2 IQSEC1	5.19e-04	477	81	8	GO:0032279
GeneOntologyCellularComponent	postsynapse	DLGAP1 CLSTN3 BMPR2 DRD1 OGT ANK2 ANK3 TRIO MARK1 CNTNAP2 IQSEC1 CHRNA5	5.29e-04	1018	81	12	GO:0098794
MousePheno	abnormal neuronal migration	DRD1 TRIO FEZF1 PAFAH1B1 CNTNAP2 KIF14	1.20e-05	114	63	6	MP:0006009
MousePheno	abnormal cell motility	FSIP2 DNAAF5 ESYT2 DRD1 RAPGEF6 LRRIQ1 TRIO FEZF1 PAFAH1B1 ARID5B CNTNAP2 CD44 KIF14 WDR62	3.04e-05	885	63	14	MP:0020846
Domain	WD40_repeat_dom	DMXL2 LLGL2 TECPR2 PAFAH1B1 LRRK1 WDR49 RIC1 WDR62 RFWD3	5.52e-06	297	81	9	IPR017986
Domain	ANK_REPEAT	GLS2 ANK2 ANK3 MUC16 LRRK1 BCL3 ANKRD55 NOTCH2	1.39e-05	253	81	8	PS50088
Domain	ANK_REP_REGION	GLS2 ANK2 ANK3 MUC16 LRRK1 BCL3 ANKRD55 NOTCH2	1.43e-05	254	81	8	PS50297
Domain	WD_REPEATS_1	DMXL2 LLGL2 TECPR2 PAFAH1B1 WDR49 RIC1 WDR62 RFWD3	2.74e-05	278	81	8	PS00678
Domain	WD_REPEATS_2	DMXL2 LLGL2 TECPR2 PAFAH1B1 WDR49 RIC1 WDR62 RFWD3	2.81e-05	279	81	8	PS50082
Domain	WD_REPEATS_REGION	DMXL2 LLGL2 TECPR2 PAFAH1B1 WDR49 RIC1 WDR62 RFWD3	2.81e-05	279	81	8	PS50294
Domain	Ank_2	GLS2 ANK2 ANK3 LRRK1 BCL3 ANKRD55 NOTCH2	4.10e-05	215	81	7	PF12796
Domain	Ank	GLS2 ANK2 ANK3 LRRK1 BCL3 ANKRD55 NOTCH2	5.95e-05	228	81	7	PF00023
Domain	-	DMXL2 LLGL2 TECPR2 PAFAH1B1 WDR49 RIC1 WDR62 RFWD3	9.75e-05	333	81	8	2.130.10.10
Domain	-	GLS2 ANK2 ANK3 LRRK1 BCL3 ANKRD55 NOTCH2	1.01e-04	248	81	7	1.25.40.20
Domain	WD40/YVTN_repeat-like_dom	DMXL2 LLGL2 TECPR2 PAFAH1B1 WDR49 RIC1 WDR62 RFWD3	1.02e-04	335	81	8	IPR015943
Domain	ANK	GLS2 ANK2 ANK3 LRRK1 BCL3 ANKRD55 NOTCH2	1.09e-04	251	81	7	SM00248
Domain	Ankyrin_rpt-contain_dom	GLS2 ANK2 ANK3 LRRK1 BCL3 ANKRD55 NOTCH2	1.17e-04	254	81	7	IPR020683
Domain	Ankyrin_rpt	GLS2 ANK2 ANK3 LRRK1 BCL3 ANKRD55 NOTCH2	1.42e-04	262	81	7	IPR002110
Domain	RhoGAP	STARD13 SYDE2 SH3BP1 ARHGAP9	1.51e-04	62	81	4	SM00324
Domain	RhoGAP	STARD13 SYDE2 SH3BP1 ARHGAP9	1.61e-04	63	81	4	PF00620
Domain	WD40	DMXL2 LLGL2 TECPR2 PAFAH1B1 WDR49 WDR62 RFWD3	1.63e-04	268	81	7	SM00320
Domain	RHOGAP	STARD13 SYDE2 SH3BP1 ARHGAP9	1.71e-04	64	81	4	PS50238
Domain	RhoGAP_dom	STARD13 SYDE2 SH3BP1 ARHGAP9	1.71e-04	64	81	4	IPR000198
Domain	-	STARD13 SYDE2 SH3BP1 ARHGAP9	1.71e-04	64	81	4	1.10.555.10
Domain	WD40_repeat	DMXL2 LLGL2 TECPR2 PAFAH1B1 WDR49 WDR62 RFWD3	1.78e-04	272	81	7	IPR001680
Domain	Rho_GTPase_activation_prot	STARD13 SYDE2 SH3BP1 ARHGAP9	5.81e-04	88	81	4	IPR008936
Domain	ZU5	ANK2 ANK3	6.56e-04	9	81	2	SM00218
Domain	ZU5	ANK2 ANK3	8.17e-04	10	81	2	PS51145
Domain	WD40	DMXL2 LLGL2 PAFAH1B1 WDR49 WDR62 RFWD3	9.14e-04	259	81	6	PF00400
Domain	ZU5	ANK2 ANK3	1.19e-03	12	81	2	PF00791
Domain	ZU5_dom	ANK2 ANK3	1.19e-03	12	81	2	IPR000906
Domain	Ser/Thr_kinase_AS	TLK1 BMPR2 TRIO MARK1 MAP3K13 LRRK1	4.56e-03	357	81	6	IPR008271
Domain	PROTEIN_KINASE_ST	TLK1 BMPR2 TRIO MARK1 MAP3K13 LRRK1	4.87e-03	362	81	6	PS00108
Domain	DEATH	ANK2 ANK3	6.08e-03	27	81	2	SM00005
Domain	Pkinase	TLK1 BMPR2 TRIO MARK1 MAP3K13 LRRK1	6.22e-03	381	81	6	PF00069
Domain	ARM-like	DNAAF5 JUP PUM1 TRRAP MN1	6.38e-03	270	81	5	IPR011989
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	FSIP2 JUP ESYT2 BMPR2 RAPGEF6 TRIO SYDE2 TET1 IQSEC1 KIF14 PUM1 NOTCH2 WDR62 RUSC2	1.59e-08	861	83	14	36931259
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	JUP RAPGEF6 OGT TET1 ARID5B KIF14 MECOM WDR62 PCNT	7.20e-07	418	83	9	34709266
Pubmed	A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.	JUP ESYT2 RAPGEF6 LLGL2 NUP155 ANK3 TRIO MARK1 NOTCH2	7.64e-07	421	83	9	36976175
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	JUP RAPGEF6 OGT ANK3 TET1 KIF14 AMOTL2 SPEN NCAPH TRRAP	7.67e-07	549	83	10	38280479
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	USF3 RAPGEF6 NUP155 ANK3 BCL9 SPEN RIC1 PCNT ZNF304	9.10e-07	430	83	9	35044719
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	DNAAF5 ESYT2 TLK1 BMPR2 USF3 OGT ANK3 TRIO TECPR2 ARID5B KIAA1328 TRRAP RIC1 NOTCH2 PCNT	2.18e-06	1489	83	15	28611215
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	DLGAP1 ESYT2 DMXL2 CACNB4 ANK2 ANK3 TRIO MARK1 VPS33A CNTNAP2 NAV3 IQSEC1 TIMM44	2.94e-06	1139	83	13	36417873
Pubmed	The ankyrin-B C-terminal domain determines activity of ankyrin-B/G chimeras in rescue of abnormal inositol 1,4,5-trisphosphate and ryanodine receptor distribution in ankyrin-B (-/-) neonatal cardiomyocytes.	ANK2 ANK3	5.63e-06	2	83	2	11781319
Pubmed	Structural basis of diverse membrane target recognitions by ankyrins.	ANK2 ANK3	5.63e-06	2	83	2	25383926
Pubmed	Ten-eleven translocation 1 (Tet1) is regulated by O-linked N-acetylglucosamine transferase (Ogt) for target gene repression in mouse embryonic stem cells.	OGT TET1	5.63e-06	2	83	2	23729667
Pubmed	The stoichiometry of scaffold complexes in living neurons - DLC2 functions as a dimerization engine for GKAP.	STARD13 DLGAP1	5.63e-06	2	83	2	24938595
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	ABRAXAS2 RAPGEF6 MARK1 KIF14 AMOTL2 PUM1 NOTCH2 WDR62	1.17e-05	446	83	8	24255178
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	TLK1 RAPGEF6 LLGL2 TRIO LRRK1 BCL9 PUM1 SPEN TRRAP RIC1 NOTCH2 PCNT	1.21e-05	1105	83	12	35748872
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	ESYT2 TLK1 RAPGEF6 IQSEC1 BCL9 SPEN TRRAP MN1 NOTCH2 WDR62	1.58e-05	774	83	10	15302935
Pubmed	Interrogating the protein interactomes of RAS isoforms identifies PIP5K1A as a KRAS-specific vulnerability.	JUP ESYT2 BMPR2 RAPGEF6 NUP155 MARK1 VPS33A NOTCH2	1.63e-05	467	83	8	30194290
Pubmed	Prognostic significance of CA 125, CD44, and epithelial membrane antigen in renal cell carcinoma.	CD44 MUC16	1.69e-05	3	83	2	12893366
Pubmed	The ammonium transporter RhBG: requirement of a tyrosine-based signal and ankyrin-G for basolateral targeting and membrane anchorage in polarized kidney epithelial cells.	ANK2 ANK3	1.69e-05	3	83	2	15611082
Pubmed	Analysis of Gene Expression Patterns of Epigenetic Enzymes Dnmt3a, Tet1 and Ogt in Murine Chondrogenic Models.	OGT TET1	1.69e-05	3	83	2	34685658
Pubmed	Human ankyrins and their contribution to disease biology: An update.	ANK2 ANK3	1.69e-05	3	83	2	33410423
Pubmed	The NOTCH pathway is recurrently mutated in diffuse large B-cell lymphoma associated with hepatitis C virus infection.	SPEN NOTCH2	1.69e-05	3	83	2	25381127
Pubmed	Ankyrin-dependent Na+ channel clustering prevents neuromuscular synapse fatigue.	ANK2 ANK3	1.69e-05	3	83	2	34289389
Pubmed	A genome-wide association study of chemotherapy-induced alopecia in breast cancer patients.	CACNB4 TRIO BCL9	1.69e-05	21	83	3	24025145
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	DLGAP1 DMXL2 CACNB4 OGT ANK2 ANK3 TRIO SH3BP1 IQSEC1 BCL9 PCNT	1.82e-05	963	83	11	28671696
Pubmed	Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.	DLGAP1 DMXL2 CACNB4 BMPR2 ANK2 IQSEC1 RUSC2	2.01e-05	347	83	7	17114649
Pubmed	Long-term potentiation modulates synaptic phosphorylation networks and reshapes the structure of the postsynaptic interactome.	DLGAP1 DMXL2 ANK2 ANK3 TRIO IQSEC1	3.16e-05	251	83	6	27507650
Pubmed	Epidermal development requires ninein for spindle orientation and cortical microtubule organization.	JUP PAFAH1B1 PCNT	3.27e-05	26	83	3	30923192
Pubmed	GKAP-DLC2 interaction organizes the postsynaptic scaffold complex to enhance synaptic NMDA receptor activity.	STARD13 DLGAP1	3.37e-05	4	83	2	22328512
Pubmed	Differential regulation of the ten-eleven translocation (TET) family of dioxygenases by O-linked β-N-acetylglucosamine transferase (OGT).	OGT TET1	3.37e-05	4	83	2	24394411
Pubmed	Cell-type-specific function of BCL9 involves a transcriptional activation domain that synergizes with beta-catenin.	BCL9 TRRAP	3.37e-05	4	83	2	18347063
Pubmed	Tet proteins connect the O-linked N-acetylglucosamine transferase Ogt to chromatin in embryonic stem cells.	OGT TET1	3.37e-05	4	83	2	23352454
Pubmed	Phosphorylation of TET proteins is regulated via O-GlcNAcylation by the O-linked N-acetylglucosamine transferase (OGT).	OGT TET1	3.37e-05	4	83	2	25568311
Pubmed	Prognostic significance of combined MN1, ERG, BAALC, and EVI1 (MEBE) expression in patients with myelodysplastic syndromes.	MECOM MN1	3.37e-05	4	83	2	22488406
Pubmed	Neuroepithelial stem cell proliferation requires LIS1 for precise spindle orientation and symmetric division.	PAFAH1B1 PCNT	3.37e-05	4	83	2	18267077
Pubmed	Notch2 activation in the embryonic kidney depletes nephron progenitors.	SIX2 NOTCH2	3.37e-05	4	83	2	20299358
Pubmed	TNFα drives pulmonary arterial hypertension by suppressing the BMP type-II receptor and altering NOTCH signalling.	BMPR2 NOTCH2	3.37e-05	4	83	2	28084316
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	NUP155 TECPR2 TET1 CNTNAP2 LRRK1 AMOTL2 NCAPH ZNF646	3.95e-05	529	83	8	14621295
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	ABRAXAS2 ESYT2 NUP155 ANK3 TRIO CD44 KIAA1328 KIF14 PUM1 SIX2 PCNT	3.96e-05	1049	83	11	27880917
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	DLGAP1 DMXL2 CLSTN3 OGT ANK2 ANK3 TRIO ARID5B NAV3 DNAAF9 AMOTL2 PCNT	5.29e-05	1285	83	12	35914814
Pubmed	CK2-regulated schwannomin-interacting protein IQCJ-SCHIP-1 association with AnkG contributes to the maintenance of the axon initial segment.	ANK2 ANK3	5.60e-05	5	83	2	25950943
Pubmed	CD44s is a crucial ATG7 downstream regulator for stem-like property, invasion, and lung metastasis of human bladder cancer (BC) cells.	TET1 CD44	5.60e-05	5	83	2	30635654
Pubmed	Glial ankyrins facilitate paranodal axoglial junction assembly.	ANK2 ANK3	5.60e-05	5	83	2	25362471
Pubmed	Association analysis of 528 intra-genic SNPs in a region of chromosome 10 linked to late onset Alzheimer's disease.	ANK3 TET1	5.60e-05	5	83	2	18163421
Pubmed	An ankyrin-based mechanism for functional organization of dystrophin and dystroglycan.	ANK2 ANK3	5.60e-05	5	83	2	19109891
Pubmed	PROSER1 mediates TET2 O-GlcNAcylation to regulate DNA demethylation on UTX-dependent enhancers and CpG islands.	OGT TET1	5.60e-05	5	83	2	34667079
Pubmed	Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.	DLGAP1 DMXL2 ANK2 ANK3 TRIO IQSEC1	5.91e-05	281	83	6	28706196
Pubmed	An inducible CRISPR/Cas9 screen identifies DTX2 as a transcriptional regulator of human telomerase.	JUP NUP155 MECOM BCL9 NOTCH2	7.36e-05	180	83	5	35198878
Pubmed	α-catenin interaction with YAP/FoxM1/TEAD-induced CEP55 supports liver cancer cell migration.	JUP ANK3 CD44	8.12e-05	35	83	3	37381005
Pubmed	TET1 regulates hypoxia-induced epithelial-mesenchymal transition by acting as a co-activator.	OGT TET1	8.39e-05	6	83	2	25517638
Pubmed	Expression analysis of Lrrk1, Lrrk2 and Lrrk2 splice variants in mice.	DRD1 LRRK1	8.39e-05	6	83	2	23675505
Pubmed	In vivo assembly of the axon initial segment in motor neurons.	ANK2 ANK3	8.39e-05	6	83	2	23728480
Pubmed	Spectrins and ankyrinB constitute a specialized paranodal cytoskeleton.	ANK2 CNTNAP2	8.39e-05	6	83	2	16687515
Pubmed	BetaIVSigma1 spectrin stabilizes the nodes of Ranvier and axon initial segments.	ANK3 CNTNAP2	8.39e-05	6	83	2	15381686
Pubmed	Functional proteomics mapping of a human signaling pathway.	STARD13 ABRAXAS2 JUP NUP155 ANK3 ARHGAP9 PUM1 NOTCH2	8.55e-05	591	83	8	15231748
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	NUP155 ANK3 SYDE2 CD44 MUC16 SPEN NCAPH NOTCH2 TRIM23	9.96e-05	777	83	9	35844135
Pubmed	CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment.	DNAAF5 ESYT2 OGT NUP155 IQSEC1 PUM1 TIMM44 WDR62	1.02e-04	606	83	8	36538041
Pubmed	Proximity interactions among centrosome components identify regulators of centriole duplication.	IQSEC1 KIF14 PUM1 PCNT	1.03e-04	101	83	4	24613305
Pubmed	Analysis of the role of membrane polarity in polycystic kidney disease of transgenic SBM mice.	ANK2 ANK3	1.17e-04	7	83	2	7495297
Pubmed	A comprehensive genetic association study of Alzheimer disease in African Americans.	RNF6 CNTNAP2	1.17e-04	7	83	2	22159054
Pubmed	Dynamic microtubules catalyze formation of navigator-TRIO complexes to regulate neurite extension.	TRIO NAV3	1.17e-04	7	83	2	25065758
Pubmed	The contribution of Notch1 to nephron segmentation in the developing kidney is revealed in a sensitized Notch2 background and can be augmented by reducing Mint dosage.	SPEN NOTCH2	1.56e-04	8	83	2	19914235
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	DMXL2 RAPGEF6 LLGL2 OGT NUP155 RIC1 RFWD3 RUSC2	1.64e-04	650	83	8	38777146
Pubmed	A human MAP kinase interactome.	DLGAP1 JUP TLK1 USF3 ANK3 KIAA1328 NAV3	1.66e-04	486	83	7	20936779
Pubmed	Interaction network of human early embryonic transcription factors.	OGT TET1 ARID5B MECOM BCL9 SPEN	1.99e-04	351	83	6	38297188
Pubmed	Potent and specific Atg8-targeting autophagy inhibitory peptides from giant ankyrins.	ANK2 ANK3	2.00e-04	9	83	2	29867141
Pubmed	Thymopoiesis requires Pax9 function in thymic epithelial cells.	PTCRA CD44	2.00e-04	9	83	2	11932925
Pubmed	C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.	JUP ESYT2 DMXL2 NUP155 VPS33A RIC1 NOTCH2	2.07e-04	504	83	7	34432599
Pubmed	Cell organization, growth, and neural and cardiac development require αII-spectrin.	ANK2 ANK3	2.50e-04	10	83	2	22159418
Pubmed	Calcium signaling induces partial EMT and renal fibrosis in a Wnt4mCherry knock-in mouse model.	ANK2 NAV3 SIX2	2.82e-04	53	83	3	38653356
Pubmed	Lis1 is essential for cortical microtubule organization and desmosome stability in the epidermis.	JUP PAFAH1B1	3.05e-04	11	83	2	21844209
Pubmed	The BCL2A1 gene as a pre-T cell receptor-induced regulator of thymocyte survival.	PTCRA CD44	3.05e-04	11	83	2	15728238
Pubmed	LIS1 regulates CNS lamination by interacting with mNudE, a central component of the centrosome.	PAFAH1B1 PCNT	3.05e-04	11	83	2	11163258
Pubmed	BioID identifies novel c-MYC interacting partners in cultured cells and xenograft tumors.	OGT SPEN NCAPH TRRAP	3.06e-04	134	83	4	25452129
Pubmed	Notch signaling promotes nephrogenesis by downregulating Six2.	SIX2 NOTCH2	3.66e-04	12	83	2	27633993
Pubmed	PRDM paralogs antagonistically balance Wnt/β-catenin activity during craniofacial chondrocyte differentiation.	MECOM BCL9	3.66e-04	12	83	2	35132438
Pubmed	Association between genes of Disrupted in schizophrenia 1 (DISC1) interactors and schizophrenia supports the role of the DISC1 pathway in the etiology of major mental illnesses.	PAFAH1B1 PCNT	3.66e-04	12	83	2	19251251
Pubmed	Novel embryonic neuronal migration and proliferation defects in Dcx mutant mice are exacerbated by Lis1 reduction.	PAFAH1B1 PCNT	3.66e-04	12	83	2	20181597
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	JUP SYDE2 ARID5B ARHGAP9 BCL3 AMOTL2 NIPAL3 ZNF304	3.78e-04	736	83	8	29676528
Pubmed	Mapping the MOB proteins' proximity network reveals a unique interaction between human MOB3C and the RNase P complex.	JUP ESYT2 OGT NUP155 CD44 NCAPH	3.94e-04	399	83	6	37536630
Pubmed	A direct physical interaction between Nanog and Sox2 regulates embryonic stem cell self-renewal.	TET1 ARID5B PUM1 TRRAP	4.23e-04	146	83	4	23892456
Pubmed	Genome-wide and candidate gene association study of cigarette smoking behaviors.	NAV3 CHRNA5	4.31e-04	13	83	2	19247474
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	CLSTN3 NAV3 PUM1 SPEN PCNT RUSC2	4.37e-04	407	83	6	12693553
Pubmed	USP9X Deubiquitylates DVL2 to Regulate WNT Pathway Specification.	ABRAXAS2 RAPGEF6 AMOTL2	4.48e-04	62	83	3	31340145
Pubmed	Revisiting the role of Notch in nephron segmentation confirms a role for proximal fate selection during mouse and human nephrogenesis.	SIX2 NOTCH2	5.03e-04	14	83	2	35451473
Pubmed	The extracellular domain of Notch2 increases its cell-surface abundance and ligand responsiveness during kidney development.	SIX2 NOTCH2	5.03e-04	14	83	2	23806616
Pubmed	Ankyrin-G regulated epithelial phenotype is required for mouse lens morphogenesis and growth.	ANK2 ANK3	5.79e-04	15	83	2	30562487
Pubmed	p62/SQSTM1 Fuels Melanoma Progression by Opposing mRNA Decay of a Selective Set of Pro-metastatic Factors.	PAFAH1B1 CD44 IQSEC1 PCNT	5.84e-04	159	83	4	30581152
Pubmed	The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells.	VPS33A ARID5B MECOM AMOTL2 SPEN	5.86e-04	282	83	5	23667531
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	DLGAP1 JUP DMXL2 CACNB4 OGT ANK2 ANK3 TRIO MARK1 PAFAH1B1 IQSEC1	5.87e-04	1431	83	11	37142655
Pubmed	A gene expression atlas of early craniofacial development.	FEZF1 SIX2	6.61e-04	16	83	2	24780627
Pubmed	Periaxin is required for hexagonal geometry and membrane organization of mature lens fibers.	ANK2 CNTNAP2	6.61e-04	16	83	2	21745462
Pubmed	Loss of cell polarity causes severe brain dysplasia in Lgl1 knockout mice.	LLGL2 PCNT	6.61e-04	16	83	2	15037549
Pubmed	Identification of 21 novel human protein kinases, including 3 members of a family related to the cell cycle regulator nimA of Aspergillus nidulans.	TLK1 MAP3K13	6.61e-04	16	83	2	8274451
Pubmed	A genome-wide association meta-analysis of plasma Aβ peptides concentrations in the elderly.	STARD13 ANK3	6.61e-04	16	83	2	24535457
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	ABRAXAS2 JUP ESYT2 DMXL2 NUP155 ANK2 ANK3 TIMM44 NOTCH2 WDR62 PCNT	8.05e-04	1487	83	11	33957083
Pubmed	Kv7/KCNQ potassium channels in cortical hyperexcitability and juvenile seizure-related death in Ank2-mutant mice.	ANK2 ANK3	8.40e-04	18	83	2	37321992
Pubmed	Ecm29-mediated proteasomal distribution modulates excitatory GABA responses in the developing brain.	ANK2 ANK3	8.40e-04	18	83	2	31910261
Pubmed	Lis1-Nde1-dependent neuronal fate control determines cerebral cortical size and lamination.	PAFAH1B1 PCNT	8.40e-04	18	83	2	18469343
Pubmed	Notch is required for the formation of all nephron segments and primes nephron progenitors for differentiation.	SIX2 NOTCH2	8.40e-04	18	83	2	29113990
Pubmed	Specification of select hypothalamic circuits and innate behaviors by the embryonic patterning gene dbx1.	NKX2-4 FEZF1	9.37e-04	19	83	2	25864637
Pubmed	MARCKS modulates radial progenitor placement, proliferation and organization in the developing cerebral cortex.	LLGL2 PCNT	9.37e-04	19	83	2	19666823
Interaction	YWHAH interactions	DLGAP1 JUP ESYT2 RAPGEF6 OGT TRIO MARK1 SYDE2 PAFAH1B1 TET1 KIF14 AMOTL2 PUM1 ANKRD55 NOTCH2 WDR62 PCNT RUSC2	3.48e-07	1102	82	18	int:YWHAH
Interaction	YWHAG interactions	DLGAP1 JUP ESYT2 RAPGEF6 OGT MARK1 SYDE2 PAFAH1B1 TET1 IQSEC1 KIF14 AMOTL2 PUM1 TRRAP ANKRD55 NOTCH2 WDR62 RUSC2	2.10e-06	1248	82	18	int:YWHAG
Interaction	RCOR1 interactions	RAPGEF6 LLGL2 OGT TET1 VPS33A ARID5B MECOM BCL3 SPEN NCAPH WDR62	5.01e-06	494	82	11	int:RCOR1
Interaction	PHF21A interactions	RAPGEF6 LLGL2 OGT TET1 ARID5B KIF14 MECOM WDR62 PCNT	1.06e-05	343	82	9	int:PHF21A
Interaction	LOC102724560 interactions	OGT KIF14 ANKRD55	1.80e-05	13	82	3	int:LOC102724560
Interaction	FARP1 interactions	DLGAP1 ESYT2 ANK2 ANK3 VPS33A KIF14	2.48e-05	142	82	6	int:FARP1
Interaction	EPHA2 interactions	JUP ESYT2 RAPGEF6 LLGL2 LRRIQ1 MAGEB10 NUP155 ANK3 TRIO MARK1 CD44 NOTCH2	3.26e-05	719	82	12	int:EPHA2
Interaction	YWHAE interactions	DLGAP1 JUP TLK1 RAPGEF6 OGT MARK1 SYDE2 PAFAH1B1 TET1 KIF14 AMOTL2 PUM1 TIMM44 ANKRD55 WDR62 RUSC2	3.94e-05	1256	82	16	int:YWHAE
Interaction	KALRN interactions	DLGAP1 ANK2 TRIO IQSEC1 PCNT	4.51e-05	96	82	5	int:KALRN
Interaction	ANKRD28 interactions	ABRAXAS2 ANK2 ANK3 PAFAH1B1 IQSEC1 BCL3 NOTCH2	4.85e-05	235	82	7	int:ANKRD28
Interaction	YWHAB interactions	DLGAP1 ESYT2 RAPGEF6 OGT MARK1 SYDE2 PAFAH1B1 KIF14 AMOTL2 PUM1 TRRAP ANKRD55 WDR62 RUSC2	5.46e-05	1014	82	14	int:YWHAB
Interaction	DYNLT1 interactions	BMPR2 RAPGEF6 OGT PAFAH1B1 IQSEC1 SPEN NCAPH	5.69e-05	241	82	7	int:DYNLT1
Interaction	PLEC interactions	JUP ANK3 SYDE2 SH3BP1 KIF14 MECOM BCL9 NCAPH PCNT	6.24e-05	430	82	9	int:PLEC
Interaction	RAC1 interactions	DLGAP1 JUP ESYT2 BMPR2 LLGL2 NUP155 ANK3 TRIO SYDE2 SH3BP1 CD44 KIF14 ARHGAP9 NOTCH2	9.05e-05	1063	82	14	int:RAC1
GeneFamily	Ankyrin repeat domain containing	GLS2 ANK2 ANK3 BCL3 ANKRD55 NOTCH2	8.16e-05	242	54	6	403
GeneFamily	WD repeat domain containing	DMXL2 LLGL2 PAFAH1B1 WDR49 WDR62 RFWD3	1.26e-04	262	54	6	362
GeneFamily	Rho GTPase activating proteins\|BCH domain containing	STARD13 SH3BP1 ARHGAP9	4.47e-04	50	54	3	721
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	STARD13 DMXL2 TLK1 OGT TRIO PAFAH1B1 ARID5B NAV3 KIF14 MECOM PUM1 SPEN TRRAP MN1 PCNT	4.96e-08	856	81	15	M4500
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN	STARD13 TLK1 OGT TRIO PAFAH1B1 ARID5B KIF14 PUM1 SPEN TRRAP	1.74e-06	466	81	10	M13522
Coexpression	DAZARD_RESPONSE_TO_UV_NHEK_DN	TLK1 PAFAH1B1 ARID5B NAV3 KIF14 PUM1 SPEN MN1	4.18e-06	300	81	8	M8702
Coexpression	BOYLAN_MULTIPLE_MYELOMA_D_DN	ZNF14 SH3BP1 CD44 LILRA6 BCL3	5.98e-06	83	81	5	M11718
Coexpression	GSE2770_IL12_AND_TGFB_VS_IL4_TREATED_ACT_CD4_TCELL_2H_DN	USF3 C10orf55 NUP155 RNF6 SPEN TRIM23	3.49e-05	198	81	6	M6128
Coexpression	HALLMARK_MITOTIC_SPINDLE	TLK1 RAPGEF6 TRIO PAFAH1B1 NOTCH2 PCNT	3.59e-05	199	81	6	M5893
Coexpression	GSE22886_NAIVE_CD8_TCELL_VS_MEMORY_TCELL_DN	TLK1 TECPR2 VPS33A ARID5B CD44 ANKRD55	3.59e-05	199	81	6	M4407
Coexpression	GSE17721_CTRL_VS_PAM3CSK4_2H_BMDC_DN	SLC38A4 RNF19B ARID5B CD44 IQSEC1 SIX2	3.69e-05	200	81	6	M3734
Coexpression	FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_OK_VS_DONOR_UP	OGT ANK2 ANK3 RNF6 PAFAH1B1 ARID5B CD44 PUM1 TRRAP	6.45e-05	568	81	9	M4023
Coexpression	MEBARKI_HCC_PROGENITOR_FZD8CRD_UP	AUNIP LRRIQ1 NUP155 KIF14 NIPAL3 MN1 CHRNA5 WDR62 RFWD3	8.40e-05	588	81	9	M38992
Coexpression	DAZARD_UV_RESPONSE_CLUSTER_G6	TLK1 PAFAH1B1 NAV3 KIF14 MN1	8.83e-05	145	81	5	M1810
Coexpression	UDAYAKUMAR_MED1_TARGETS_DN	TRIO ARID5B AMOTL2 MN1 ZXDA PCNT	1.11e-04	244	81	6	M9945
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	ESYT2 TLK1 OGT ANK3 KIAA1328 LRRK1 ANKRD55	6.79e-08	190	83	7	91ba66d4b56c59523485b17738e93f14bb00afa4
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ANK3 TRIO CNTNAP2 NAV3 SIX2 NOTCH2	1.00e-06	177	83	6	7af1a19692f7fe8f691178a4e57d62bc379e3d56
ToppCell	PSB-critical-LOC-Epithelial-FOXN4+\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CNTNAP2 KIF14 NCAPH CHRNA5 WDR62 PCNT	1.65e-06	193	83	6	b7d9c5bed524423e92f01496a9f8fad11b33a3f7
ToppCell	COVID-19-Epithelial_cells-Airway_mucous\|COVID-19 / group, cell type (main and fine annotations)	LRRIQ1 CNTNAP2 MUC16 MECOM WDR49	9.37e-06	151	83	5	8216462e723fec2797387929dde095370947e10a
ToppCell	5'-Parenchyma_lung-Immune_Myeloid-Dendritic-CD1c-positive_myeloid_dendritic_cell-DC2_(CD1c+_dendritic_cell)-DC2_L.1.2.1.3\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	C10orf55 RNF19B LRRK1 WDR49 RIC1	1.44e-05	165	83	5	76abebe80e5f8bf44825bb619ae86fcb6f66ffeb
ToppCell	3'-Adult-Appendix-Epithelial-mature_enterocytic\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FSIP2 MARK1 DNAAF9 NIPAL3 WDR62	1.96e-05	176	83	5	30adf8f1638c6244586f8101c2590bb964dfae00
ToppCell	3'-Adult-Appendix-Epithelial-mature_enterocytic-Colonocyte\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FSIP2 MARK1 DNAAF9 NIPAL3 WDR62	1.96e-05	176	83	5	23fa02d4c39e0b8faa1658116d50b6233a952ccc
ToppCell	P15-Epithelial-epithelial_progenitor_cell-epithelial_unknown_3\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	STARD13 DLGAP1 ANK3 BCL9 RFWD3	1.96e-05	176	83	5	792f414f5092aba14260b8e16378e793a822498e
ToppCell	NS-moderate-d_0-4-Lymphoid-NKT-proliferating\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CNTNAP2 KIF14 NCAPH CHRNA5 WDR62	2.02e-05	177	83	5	174c54acfe19e2bb31418d69e228032ba724cbb6
ToppCell	wk_20-22-Mesenchymal-Chondrocyte-intermediate_chondrocyte\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	DLGAP1 MECOM BCL9 MN1 RUSC2	2.37e-05	183	83	5	1464b5c4425e8776c4aeb4d2b560481d4bf13931
ToppCell	Mild/Remission-B_intermediate-10\|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)	BMPR2 ANK2 ANK3 IQSEC1 LRRK1	2.37e-05	183	83	5	278064c9f0582463b83bf156d34e77f60187613b
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	JUP ESYT2 LRRIQ1 CD44 MECOM	2.62e-05	187	83	5	87b3d0478693d4c54ff06b74e5903036b9c1ee6a
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	JUP ESYT2 LRRIQ1 CD44 MECOM	2.62e-05	187	83	5	42a1267bfc27b4460b8409ada580a87c4385841c
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	JUP ESYT2 LRRIQ1 CD44 MECOM	2.62e-05	187	83	5	64afdea159f5e67a1e5cea35ce898aae6e80aea5
ToppCell	severe_COVID-19-CD4+_T_naive\|World / disease group, cell group and cell class (v2)	RAPGEF6 ANK3 SYDE2 ARID5B ANKRD55	2.90e-05	191	83	5	55a282478488efd1561ea57a6f0218f55f711bb0
ToppCell	Parenchymal-10x5prime-Epithelial-Epi_airway_neuro-secretory-Ionocyte_n_Brush\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	LLGL2 ANK2 NAV3 MUC16 KIF14	3.13e-05	194	83	5	ea5b7727ffef6cb454c501979a51bc1d4108d0e4
ToppCell	severe_COVID-19-CD4+_T_naive\|severe_COVID-19 / disease group, cell group and cell class (v2)	RAPGEF6 ANK3 SYDE2 ARID5B ANKRD55	3.13e-05	194	83	5	4b86f3cc173ea779399d5b3598b45b25f60a4395
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	LLGL2 ANK3 MECOM DNAAF9 MAP3K13	3.21e-05	195	83	5	6477e6e7be5bd8eb99119a12ae16334ccddecd43
ToppCell	COVID-19-T_cells-Cycling_NK/T_cells\|COVID-19 / group, cell type (main and fine annotations)	KIF14 NCAPH WDR62 RFWD3 PCNT	3.21e-05	195	83	5	764ed100c28d9bc93ee5ecabc5291c8f184d78da
ToppCell	facs-Lung-3m\|Lung / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ESYT2 ANK3 SLC38A4 IQSEC1 NOTCH2	3.21e-05	195	83	5	c4648c0332c3826776f9ad3f5f803dbac2b4c0c0
ToppCell	10x_5'_v1-Non-neoplastic-Lymphoid-CD4/CD8-Stress_sig-F_2\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	OGT ANK3 CD44 PUM1 MN1	3.29e-05	196	83	5	ea8eceacc5d5e1a22b77c31e7c45985dc7bb15de
ToppCell	IPF-Lymphoid-T\|Lymphoid / Disease state, Lineage and Cell class	RAPGEF6 OGT ANK3 CD44 ANKRD55	3.29e-05	196	83	5	6e70c48a63d9673eb16b0847c1bd88eecc2f7a3c
ToppCell	COPD-Lymphoid-T\|Lymphoid / Disease state, Lineage and Cell class	RAPGEF6 OGT ANK3 CD44 ANKRD55	3.29e-05	196	83	5	c9bdd505c3ab380ed7b272aa518df31a0a706a06
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DLGAP1 LLGL2 ANK3 CD44 MECOM	3.37e-05	197	83	5	7e93a97b5ac5ae2f77a4b3141082a1463fed00dd
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-Trm_Th1/Th17\|GI_small-bowel / Manually curated celltypes from each tissue	DLGAP1 ANK3 RNF19B CD44 BCL3	3.45e-05	198	83	5	f4fc0cac858fc6dcd779d7959ccec51f78ea8cc2
ToppCell	Tracheal-NucSeq-Epithelial-Epi_airway_ciliated-Deuterosomal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	LRRIQ1 KIF14 NCAPH WDR49 WDR62	3.45e-05	198	83	5	f31790442ef142f1c0c49bf3daf2d0efb193d2c9
ToppCell	Parenchymal-NucSeq\|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations	STARD13 ANK3 TRIO KIAA1328 MECOM	3.45e-05	198	83	5	1996373bdccc55aac347d349bd22f6aad6d0c668
ToppCell	mLN-T_cell-cycling_gd_T\|T_cell / Region, Cell class and subclass	AUNIP KIF14 NCAPH WDR49 WDR62	3.53e-05	199	83	5	c81a194f8c2f120c6c4d74857912865a3c2fe1e7
ToppCell	Bronchial-NucSeq-Epithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CACNB4 LLGL2 ANK3 MECOM MAP3K13	3.53e-05	199	83	5	5f7da3eab58ace6cddb3179a415cd839d5767958
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CACNB4 LLGL2 ANK3 MECOM MAP3K13	3.53e-05	199	83	5	8587bd98de7767a575088afbea07a1feb4516b9b
ToppCell	(1)_T_cell-(18)_cycling_gd_T\|(1)_T_cell / shred on Cell_type and subtype	AUNIP KIF14 NCAPH WDR49 WDR62	3.53e-05	199	83	5	9369d0e4efe809e3e8757294ebebba5a47b30528
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW13-Stem_cells\|GW13 / Sample Type, Dataset, Time_group, and Cell type.	DMXL2 NUP155 NCAPH WDR62 PCNT	3.62e-05	200	83	5	d933978b55fefe52cad599b36f6b47a0c7f71f96
ToppCell	TCGA-Bile_Duct-Primary_Tumor-Cholangiocarcinoma-Intrahepatic\|TCGA-Bile_Duct / Sample_Type by Project: Shred V9	TRIO DNAAF9 BCL9 NOTCH2 TRIM23	3.62e-05	200	83	5	1fa8422fd820d21e285a7e7c4c6fbd8b7277d2af
ToppCell	mLN-T_cell-cycling_gd_T\|mLN / Region, Cell class and subclass	AUNIP KIF14 NCAPH WDR49 WDR62	3.62e-05	200	83	5	4efeef51f885ee8f6dd3911a536cc49e3c14da98
ToppCell	Tracheal-NucSeq-Epithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CACNB4 LLGL2 ANK3 MUC16 MAP3K13	3.62e-05	200	83	5	d3af0a706baf66e3f32e67b17dcfc31e5b32ce0e
ToppCell	mLN-(1)_T_cell-(18)_cycling_gd_T\|mLN / shred on region, Cell_type, and subtype	AUNIP KIF14 NCAPH WDR49 WDR62	3.62e-05	200	83	5	e8a0a88a8344e80783931115bbe6cd5b62a4c1f7
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW13-Stem_cells-Neuroepithelial_cell\|GW13 / Sample Type, Dataset, Time_group, and Cell type.	DMXL2 NUP155 NCAPH WDR62 PCNT	3.62e-05	200	83	5	3d932765c31aef1f80a118d51e8e66c50a758dbb
ToppCell	Tracheal-NucSeq-Epithelial-Epi_submucosal-gland\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CACNB4 LLGL2 ANK3 MUC16 MAP3K13	3.62e-05	200	83	5	0eb9ad8c0373bcc62029ec21c590ed03aaacd039
ToppCell	TCGA-Cervix-Primary_Tumor-Cervical_Carcinoma-Cervical_Squamous_Cell_Carcinoma-3\|TCGA-Cervix / Sample_Type by Project: Shred V9	LRRK1 NIPAL3 SPEN RIC1	8.01e-05	122	83	4	1ed865f0ecfe304fb86313ff51c04e9052357270
ToppCell	ASK440-Endothelial-Endothelium\|Endothelial / Donor, Lineage and Cell class of Lung cells from Dropseq	BMPR2 MECOM PUM1 SPEN	8.01e-05	122	83	4	2f76ec3b527e9528fbb006599a96e8bbdf9e0e62
ToppCell	droplet-Tongue-Unstain-18m-Epithelial-nan\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTCRA MARK1 KIAA1328 NOTCH2	1.12e-04	133	83	4	f7d0763b5eec2db33044d6850fd57462494038c1
ToppCell	356C-Epithelial_cells-Epithelial-E_(AT2)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	ABRAXAS2 ZNF14 TET1 AMOTL2	1.40e-04	141	83	4	31e0984f09983e83a814424f74c871c1c5a3a789
ToppCell	356C-Epithelial_cells-Epithelial-E_(AT2)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	ABRAXAS2 ZNF14 TET1 AMOTL2	1.40e-04	141	83	4	d7d3c3932651d90fa4f3c4e3df16f4b677faaf9f
ToppCell	LPS-antiTNF-Epithelial_alveolar-Mes-like-Differentiating_AT2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DLGAP1 ANK2 BCL9 ANKRD55	1.44e-04	142	83	4	5690eee2ce1ecd02e34eac4193578bd13c4228b9
ToppCell	facs-Lung-Endomucin-3m-Myeloid\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD44 LILRA6 ARHGAP9 NOTCH2	1.87e-04	152	83	4	962f5bf632da79bd933193d3edd7d89941a85831
ToppCell	3'_v3-blood-Lymphocytic_T_CD4-Tfh\|blood / Manually curated celltypes from each tissue	TLK1 ANK3 ARID5B ANKRD55	1.97e-04	154	83	4	5ff380205fa7ab97ba21f6512bc9e14c0fb320b6
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CACNB4 OGT MECOM WDR49	2.07e-04	156	83	4	4d2679e7639758c49fc25a2deb9109b08f0a3e57
ToppCell	facs-Lung-Endomucin_-18m-Myeloid\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DMXL2 CD44 LILRA6 ARHGAP9	2.12e-04	157	83	4	2b60de520edf167f5ca790b478557a778435b3d9
ToppCell	Children_(3_yrs)-Epithelial-basal_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CACNB4 ANK3 MARK1 MECOM	2.12e-04	157	83	4	6ee2692f705bdd93ba523dffaf2f0cd921b47e28
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	RAPGEF6 ARID5B BCL9 ANKRD55	2.22e-04	159	83	4	b9d34b9ed8db798f5ea93c44b469cae499403cb8
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Myeloid-nan\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DMXL2 CD44 LILRA6 ARHGAP9	2.22e-04	159	83	4	a6093b230afdd4d91870d289c6ac91d1856666a3
ToppCell	facs-Brain_Non-Myeloid-Cortex_-18m-Lymphocytic-T_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AUNIP CD44 KIF14 ANKRD55	2.27e-04	160	83	4	94e4f5fc2156dd8163811c3b8b0781ea9b3f2e06
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	AUNIP KIF14 NCAPH WDR62	2.44e-04	163	83	4	3f434015c0cbefb31eeda133c34f75384c5f7e22
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	KIF14 NCAPH WDR62 RFWD3	2.68e-04	167	83	4	bc132b51dec4e8f1cd2b2cd89f83641976e09292
ToppCell	normal_Lung-T/NK_cells-Exhausted_CD8+_T\|T/NK_cells / Location, Cell class and cell subclass	STARD13 CD44 NAV3 MN1	2.74e-04	168	83	4	76b49463895cdef27c90f831c6246bcb92b9761b
ToppCell	3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ZNF14 MUC16 CHRNA5 WDR62	2.74e-04	168	83	4	de0b00bc405c898d08a06b2e585fb62c0ab9a66e
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Myeloid-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DMXL2 BMPR2 CD44 LILRA6	2.87e-04	170	83	4	f3d5678669dcaed1836014cea543758b7ccc6b46
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	KIF14 NCAPH WDR49 WDR62	2.93e-04	171	83	4	55c7bf7211587fa08df13c0a4ff5b78a85d5439e
ToppCell	368C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	AUNIP LRRK1 CHRNA5 WDR62	3.06e-04	173	83	4	20889aa85e36ad3bafdb91b91e43964493c949f9
ToppCell	368C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	AUNIP LRRK1 CHRNA5 WDR62	3.06e-04	173	83	4	46e601b7938b1dd0aa3df7aa056c4bd07b1620c1
ToppCell	E16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	STARD13 DNAAF5 BMPR2 ANK2	3.20e-04	175	83	4	1d8aab491dcc27ea5dbfb6462d18ee280b21a05e
ToppCell	E16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	STARD13 DNAAF5 BMPR2 ANK2	3.20e-04	175	83	4	427a7ee92fe16a90625946492062d37aa0f7235b
ToppCell	368C-Lymphocytic-CD4_T-cell-Proliferating_T_cell\|368C / Donor, Lineage, Cell class and subclass (all cells)	C10orf55 CNTNAP2 KIF14 NCAPH	3.20e-04	175	83	4	74800a10f5ff25d5414fbccb0668f92ff077d1cc
ToppCell	facs-Skin-Anagen-24m-Epithelial-actively_dividing_stem_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AUNIP KIF14 NCAPH WDR62	3.34e-04	177	83	4	8a0f0fbb06cdacb99a3fdba0da3e0494b891db4f
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_low-phase\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	AUNIP KIF14 CHRNA5 WDR62	3.34e-04	177	83	4	75049e5372d14edeb5768339359396b73a85c2cc
ToppCell	facs-Skin-Anagen-24m-Epithelial-keratinocyte_stem_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AUNIP KIF14 NCAPH WDR62	3.34e-04	177	83	4	e9d7682517fb30fd2ad535d59779d718a7024c13
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	AUNIP CHRNA5 WDR62 RFWD3	3.48e-04	179	83	4	88d44b04eb5c079531db663ed98ddb20b60feb9a
ToppCell	Epithelial-basal_cell\|World / Lineage, Cell type, age group and donor	ANK3 MARK1 MECOM WDR49	3.48e-04	179	83	4	d9be6647ec7b22747dc00dce4ea307b6af412dfa
ToppCell	Control-Epithelial_cells-AT2\|Control / group, cell type (main and fine annotations)	DLGAP1 CACNB4 ANK3 MECOM	3.56e-04	180	83	4	198b19e7910b4a8cc7e820c525ab357c7f99f578
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	STARD13 ANK3 TET1 MECOM	3.56e-04	180	83	4	023ec0b080c8a5cd0f36e83c6b17d4be3c01edb5
ToppCell	10x5'-lymph-node_spleen-Myeloid_Mac-Cycling_Myeloid-Mac\|lymph-node_spleen / Manually curated celltypes from each tissue	STARD13 DMXL2 KIF14 NCAPH	3.56e-04	180	83	4	4eea8366cdb82c356325ce88f09ad8b302c17a07
ToppCell	5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_proliferating-Alveolar_macrophage_proliferating_L.1.0.7.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	KIF14 NCAPH CHRNA5 RFWD3	3.63e-04	181	83	4	73b1b59810f60e3e39ca1d5073a5a0d4f5377e6e
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	LLGL2 ANK3 MECOM MAP3K13	3.63e-04	181	83	4	576da14ab3107f89e1f44a4a439d1bef5bb42370
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling-Cycling_Connecting_Tubule_Cell_G2M\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	KIF14 NCAPH WDR62 RFWD3	3.71e-04	182	83	4	336cd05e46a741185ce3c59ee67a4b07fa6a5101
ToppCell	mild_COVID-19_(asymptomatic)-T/NK_proliferative\|World / disease group, cell group and cell class (v2)	AUNIP KIF14 NCAPH WDR62	3.71e-04	182	83	4	9adf90bb2808f234d53b89ca0ae07380478204ad
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CACNB4 ANK3 MECOM MAP3K13	3.79e-04	183	83	4	6847c1252d6bb105524f812658112517fd351eab
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	STARD13 ANK3 SLC38A4 MECOM	3.79e-04	183	83	4	b5ede5a0048c585b73c00e88aeddbcaf669347b1
ToppCell	mild_COVID-19_(asymptomatic)-T/NK_proliferative\|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)	AUNIP KIF14 NCAPH WDR62	3.79e-04	183	83	4	df8568751205313d149939ea2683097e3652a60b
ToppCell	PBMC-Control-Myeloid-Neutrophil-immature_Neutrophil\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	DMXL2 KIF14 NCAPH PCNT	3.87e-04	184	83	4	a8c6028d745aaa6ee7842259238694cb50ce0526
ToppCell	PBMC-Control-Myeloid-Neutrophil-immature_Neutrophil-Neu_4\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	DMXL2 KIF14 NCAPH PCNT	3.87e-04	184	83	4	081d045f3bc98a36f342de7d50f39c9a888dd7eb
ToppCell	Control-Myeloid_G-immature_Neutrophil\|Control / Disease group, lineage and cell class	DMXL2 KIF14 NCAPH PCNT	3.87e-04	184	83	4	45f873236f7e90fb78c8e291d3b5b92d121acec9
ToppCell	PBMC-Control-Myeloid-Neutrophil-immature_Neutrophil\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	DMXL2 KIF14 NCAPH PCNT	3.87e-04	184	83	4	84c20730cd92b9aaa50077d7b625e37e7f9e91d2
ToppCell	COPD-Myeloid-cMonocyte\|World / Disease state, Lineage and Cell class	DLGAP1 RNF19B BCL3 NOTCH2	3.87e-04	184	83	4	ceec41ed5636032aaf7716d1203816ea58bd39bd
ToppCell	PBMC-Control-Myeloid-Neutrophil-immature_Neutrophil-Neu_4\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	DMXL2 KIF14 NCAPH PCNT	3.87e-04	184	83	4	d31d4116d1d196633784863781fa45673607a421
ToppCell	Control-Neu_4\|World / 5 Neutrophil clusters in COVID-19 patients	DMXL2 KIF14 NCAPH PCNT	3.87e-04	184	83	4	ce7f044956613118ee2e9fb6af2455c3166cb414
ToppCell	facs-Lung-24m-Hematologic-myeloid\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SH3BP1 CD44 ARHGAP9 NOTCH2	3.87e-04	184	83	4	c451acfcd8fe28c1f4b1ea334b1129fa84a15c42
ToppCell	nucseq-Immune-Lymphocytic_B-Lymphocytic_B-Plasma\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	OGT SLC38A4 LRRK1 RIC1	3.95e-04	185	83	4	3b77bc49cd3740acc025e162a36282ac09e12198
ToppCell	CV-Moderate-7\|Moderate / Virus stimulation, Condition and Cluster	DMXL2 NUP155 KIF14 SPEN	3.95e-04	185	83	4	a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCell	367C-Lymphocytic-NK_cells-NK_cell_D3\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	ZNF14 CD44 MAP3K13 RFWD3	3.95e-04	185	83	4	4a5e70ac41e5f3b25a773304ffef3c2a3dd5549d
ToppCell	10x5'-lymph-node_spleen-Myeloid_Dendritic-Cycling_Dendritic\|lymph-node_spleen / Manually curated celltypes from each tissue	AUNIP KIF14 NCAPH MN1	3.95e-04	185	83	4	912d8efdc37820dbb07736221a98af929e5a7c97
ToppCell	facs-Skin-Telogen-3m-Epithelial-actively_dividing_stem_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AUNIP KIF14 NCAPH WDR62	4.03e-04	186	83	4	9feef5936985e936b3d88f9d1bb012abb6468570
ToppCell	CV-Moderate-7\|CV / Virus stimulation, Condition and Cluster	DMXL2 NUP155 KIF14 SPEN	4.03e-04	186	83	4	8571956890fc9894d766ba294a28e376b4aba428
ToppCell	facs-Skin-Telogen-3m-Epithelial-keratinocyte_stem_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AUNIP KIF14 NCAPH WDR62	4.03e-04	186	83	4	89f5b06bc56674af304912d481ac697c7c870904
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	KIF14 NCAPH WDR62 RFWD3	4.11e-04	187	83	4	9351fa87b69a951af85b10bf91fe9b1cce8c0517
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	KIF14 NCAPH WDR62 RFWD3	4.11e-04	187	83	4	057569c9437219ecc396aa6e673b1178a2273837
ToppCell	COVID-19-Epithelial_cells\|COVID-19 / group, cell type (main and fine annotations)	LLGL2 ANK3 MECOM MAP3K13	4.19e-04	188	83	4	c9cdee6f8d42ee69f5fb335f25084603c511bd29
ToppCell	TCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Colon_Adenocarcinoma-7\|TCGA-Colorectal / Sample_Type by Project: Shred V9	RNF6 TRIO AMOTL2 RUSC2	4.19e-04	188	83	4	14bc73cf79c79c9f208369fd8d498e5b26e0114d
ToppCell	3'_v3-lymph-node_spleen-Myeloid_Dendritic-Cycling_Dendritic\|lymph-node_spleen / Manually curated celltypes from each tissue	AUNIP C10orf55 KIF14 NCAPH	4.19e-04	188	83	4	723348a1836a074e068320cb736ce6a953e0038f
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2-D231\|Adult / Lineage, Cell type, age group and donor	DLGAP1 CACNB4 ANK3 MECOM	4.28e-04	189	83	4	dab54a52358f66a8a9460cd6089a06c5fa7e7a5d
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c06-NR4A2\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	TLK1 ANK3 ARID5B ANKRD55	4.28e-04	189	83	4	8130102c41b2978a8b83f765ce383f836a464795
Drug	irinotecan HCl; Down 200; 100uM; MCF7; HT_HG-U133A	STARD13 TLK1 TRIO PAFAH1B1 ARID5B KIF14 MECOM NCAPH	2.40e-07	174	83	8	7530_DN
Drug	Phenoxybenzamine hydrochloride [63-92-3]; Down 200; 11.8uM; MCF7; HT_HG-U133A	STARD13 ANK3 ARID5B MECOM BCL3 NCAPH NOTCH2 WDR62	4.33e-07	188	83	8	6451_DN
Drug	Metanephrine hydrochloride DL [881-95-8]; Up 200; 17.2uM; PC3; HG-U133A	JUP LLGL2 VPS33A IQSEC1 MECOM BCL3 BCL9 SIX2	6.17e-07	197	83	8	1933_UP
Drug	Raloxifene hydrochloride [82640-04-8]; Up 200; 7.8uM; HL60; HT_HG-U133A	BORCS8 DLGAP1 CACNB4 GLS2 ANK3 TRIO MECOM	6.57e-06	192	83	7	2738_UP
Drug	Thiocolchicoside [602-41-5]; Down 200; 7uM; MCF7; HT_HG-U133A	STARD13 OGT TRIO CD44 IQSEC1 SIX2 NOTCH2	7.27e-06	195	83	7	5520_DN
Drug	Niflumic acid [4394-00-7]; Down 200; 14.2uM; PC3; HT_HG-U133A	RNF6 CNTNAP2 NAV3 BCL9 SIX2 TRIM23 RUSC2	7.52e-06	196	83	7	5071_DN
Drug	Vitamin K2 [11032-49-8]; Down 200; 9uM; PC3; HT_HG-U133A	BORCS8 TLK1 TRIO MARK1 LRRK1 BCL3 TRIM23	7.77e-06	197	83	7	3798_DN
Drug	aspirin, USP; Down 200; 100uM; MCF7; HT_HG-U133A	BORCS8 GLS2 PTCRA RNF19B VPS33A CD44 SIX2	7.77e-06	197	83	7	5201_DN
Drug	Bromopride [4093-35-0]; Down 200; 11.6uM; HL60; HT_HG-U133A	BMPR2 VPS33A BCL3 NIPAL3 TRIM23 RUSC2 ZNF304	8.03e-06	198	83	7	2182_DN
Drug	Oxalamine citrate salt [1949-20-8]; Down 200; 9.2uM; PC3; HT_HG-U133A	STARD13 GLS2 RNF6 TRIO CNTNAP2 LRRK1 BCL9	8.30e-06	199	83	7	6624_DN
Drug	Withaferin A [5119-48-2]; Up 200; 1uM; PC3; HT_HG-U133A	MARK1 NAV3 MAP3K13 NIPAL3 CHRNA5 RUSC2	5.28e-05	181	83	6	3819_UP
Drug	0179445-0000 [211246-22-9]; Down 200; 10uM; MCF7; HT_HG-U133A	STARD13 TECPR2 ARID5B KIF14 MECOM RFWD3	5.44e-05	182	83	6	3630_DN
Drug	Parthenolide [20554-84-1]; Down 200; 16.2uM; MCF7; HT_HG-U133A	ARID5B CD44 IQSEC1 MECOM BCL9 NOTCH2	5.61e-05	183	83	6	5530_DN
Drug	17-AAG; Down 200; 1uM; MCF7; HT_HG-U133A	TLK1 TRIO PTCRA MECOM BCL3 TRIM23	6.91e-05	190	83	6	5223_DN
Drug	Rapamycin; Up 200; 0.1uM; MCF7; HT_HG-U133A	TLK1 DRD1 ANK2 TRIO PTCRA CNTNAP2	7.12e-05	191	83	6	5581_UP
Drug	Lasalocid sodium salt [25999-20-6]; Down 200; 6.6uM; PC3; HT_HG-U133A	BORCS8 GLS2 TRIO TECPR2 CNTNAP2 SIX2	7.32e-05	192	83	6	6639_DN
Drug	PNU-0293363 [326823-19-2]; Up 200; 10uM; MCF7; HT_HG-U133A	TRIO PAFAH1B1 TIMM44 TRRAP CHRNA5 NOTCH2	7.32e-05	192	83	6	6573_UP
Drug	Triprolidine hydrochloride [550-70-9]; Up 200; 12.8uM; PC3; HT_HG-U133A	TRIO RNF19B NAV3 LRRK1 AMOTL2 TRIM23	7.32e-05	192	83	6	7248_UP
Drug	Bacampicillin hydrochloride [37661-08-8]; Down 200; 8uM; MCF7; HT_HG-U133A	BORCS8 RNF6 TRIO RNF19B NOTCH2 TRIM23	7.75e-05	194	83	6	3273_DN
Drug	Nisoxetine hydrochloride [57754-86-6]; Up 200; 13uM; PC3; HT_HG-U133A	BORCS8 TRIO CNTNAP2 NAV3 MAP3K13 TRIM23	7.75e-05	194	83	6	5091_UP
Drug	SnBr4	ARHGAP9 BCL3	7.84e-05	4	83	2	CID000024616
Drug	Epicatechin-(-) [154-23-4]; Up 200; 13.8uM; HL60; HT_HG-U133A	BORCS8 CLSTN3 BMPR2 NIPAL3 SIX2 RUSC2	7.98e-05	195	83	6	2160_UP
Drug	Ethionamide [536-33-4]; Up 200; 24uM; PC3; HT_HG-U133A	DLGAP1 TLK1 RNF6 CNTNAP2 MECOM MAP3K13	7.98e-05	195	83	6	4593_UP
Drug	Retrorsine [480-54-6]; Down 200; 11.4uM; PC3; HT_HG-U133A	RNF6 CD44 NAV3 LRRK1 NOTCH2 WDR62	8.21e-05	196	83	6	6601_DN
Drug	Aceclofenac [89796-99-6]; Up 200; 11.2uM; PC3; HT_HG-U133A	OGT RNF6 CNTNAP2 MAP3K13 NOTCH2 TRIM23	8.44e-05	197	83	6	2117_UP
Drug	Florfenicol [73231-34-2]; Up 200; 11.2uM; MCF7; HT_HG-U133A	BORCS8 CNTNAP2 CD44 IQSEC1 BCL9 WDR62	8.44e-05	197	83	6	5300_UP
Drug	Diltiazem hydrochloride [33286-22-5]; Up 200; 8.8uM; MCF7; HT_HG-U133A	RNF6 RNF19B IQSEC1 BCL9 WDR62 ZNF304	8.44e-05	197	83	6	5309_UP
Drug	chlorpromazine hydrochloride; Up 200; 1uM; MCF7; HT_HG-U133A	CLSTN3 MARK1 RNF19B SIX2 WDR62 RUSC2	8.44e-05	197	83	6	6936_UP
Drug	Pancuronium bromide [15500-66-0]; Up 200; 5.4uM; PC3; HT_HG-U133A	GLS2 PTCRA CNTNAP2 MAP3K13 LRRK1 BCL3	8.44e-05	197	83	6	4570_UP
Drug	2-propylpentanoic acid; Down 200; 50uM; MCF7; HT_HG-U133A	STARD13 BORCS8 TRIO PTCRA RNF19B MECOM	8.68e-05	198	83	6	5219_DN
Drug	Triamcinolone [124-94-7]; Down 200; 10.2uM; PC3; HT_HG-U133A	TRIO RNF19B VPS33A LRRK1 BCL9 NOTCH2	8.68e-05	198	83	6	5835_DN
Drug	Megestrol acetate [595-33-5]; Down 200; 10.4uM; HL60; HT_HG-U133A	CACNB4 ANK3 PTCRA VPS33A SIX2 WDR62	8.68e-05	198	83	6	3091_DN
Drug	Bufexamac [2438-72-4]; Up 200; 18uM; MCF7; HT_HG-U133A	CACNB4 DRD1 GLS2 TECPR2 CNTNAP2 MN1	8.68e-05	198	83	6	5515_UP
Drug	Hyoscyamine (L) [101-31-5]; Down 200; 13.8uM; MCF7; HT_HG-U133A	PAFAH1B1 RNF19B CD44 MECOM BCL9 SIX2	8.68e-05	198	83	6	5524_DN
Drug	Meclozine dihydrochloride [1104-22-9]; Up 200; 8.6uM; HL60; HT_HG-U133A	BMPR2 ANK3 RNF6 PTCRA VPS33A SH3BP1	8.68e-05	198	83	6	2424_UP
Drug	Thiethylperazine malate [52239-63-1]; Up 200; 6uM; HL60; HT_HG-U133A	STARD13 BMPR2 RNF6 PTCRA IQSEC1 SIX2	8.68e-05	198	83	6	6154_UP
Drug	Methotrimeprazine maleat salt [7104-38-3]; Down 200; 9uM; PC3; HT_HG-U133A	RNF6 TRIO CNTNAP2 SIX2 TRIM23 RFWD3	8.68e-05	198	83	6	7399_DN
Drug	Ticlopidine hydrochloride [53885-35-1]; Down 200; 13.4uM; PC3; HT_HG-U133A	STARD13 GLS2 NAV3 TRRAP SIX2 NOTCH2	8.68e-05	198	83	6	4074_DN
Drug	AC1L9LT0	DLGAP1 JUP LLGL2 ANK2 ANK3	8.79e-05	123	83	5	CID000448294
Drug	Glycocholic acid [475-31-0]; Up 200; 8.6uM; HL60; HT_HG-U133A	RNF6 TRIO VPS33A NOTCH2 TRIM23 ZNF646	8.92e-05	199	83	6	2454_UP
Drug	Lobeline alpha (-) hydrochoride [134-63-4]; Down 200; 10.6uM; PC3; HT_HG-U133A	GLS2 PTCRA LRRK1 BCL9 TRIM23 WDR62	8.92e-05	199	83	6	5784_DN
Drug	Nitrofural [59-87-0]; Up 200; 20.2uM; HL60; HT_HG-U133A	STARD13 DMXL2 RNF6 PTCRA NOTCH2 TRIM23	9.17e-05	200	83	6	2459_UP
Drug	SB 203580; Up 200; 1uM; PC3; HT_HG-U133A	BORCS8 PTCRA MN1 SIX2 NOTCH2 RUSC2	9.17e-05	200	83	6	6894_UP
Drug	Oxytetracycline dihydrate [6153-64-6]; Down 200; 8uM; PC3; HT_HG-U133A	RNF6 PTCRA RNF19B NAV3 SIX2 RUSC2	9.17e-05	200	83	6	5772_DN
Drug	cytochalasin B; Up 200; 20.8uM; MCF7; HT_HG-U133A_EA	ANK3 TRIO ARID5B CD44 BCL3	4.30e-04	173	83	5	1122_UP
Drug	3-doxylandrostanol	ANK2 ANK3	4.65e-04	9	83	2	CID000189075
Drug	Puromycin dihydrochloride [58-58-2]; Up 200; 7.4uM; PC3; HT_HG-U133A	ZNF14 RNF19B ARID5B MAP3K13 BCL3	5.02e-04	179	83	5	6711_UP
Drug	Trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A	TLK1 OGT TRIO BCL3 AMOTL2	5.28e-04	181	83	5	6951_DN
Drug	irinotecan HCl; Down 200; 100uM; MCF7; HT_HG-U133A	TLK1 ARID5B KIF14 NCAPH TRRAP	5.55e-04	183	83	5	7498_DN
Drug	Chloropyramine hydrochloride [6170-42-9]; Up 200; 12.2uM; PC3; HT_HG-U133A	GLS2 TRIO NAV3 LRRK1 AMOTL2	6.13e-04	187	83	5	4589_UP
Drug	15d-PGJ2; Down 200; 10uM; MCF7; HT_HG-U133A	STARD13 VPS33A ARID5B BCL3 NCAPH	6.13e-04	187	83	5	6948_DN
Drug	Trifluoperazine dihydrochloride [440-17-5]; Up 200; 8.4uM; MCF7; HT_HG-U133A	CACNB4 CLSTN3 TECPR2 RNF19B CD44	6.28e-04	188	83	5	5442_UP
Drug	Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; HL60; HT_HG-U133A	JUP PTCRA TECPR2 ARID5B MECOM	6.28e-04	188	83	5	2370_UP
Drug	Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; HL60; HT_HG-U133A	CACNB4 BMPR2 ANK2 IQSEC1 NIPAL3	6.28e-04	188	83	5	6143_UP
Drug	resveratrol; Down 200; 50uM; MCF7; HG-U133A	GLS2 ANK3 TRIO IQSEC1 BCL3	6.28e-04	188	83	5	595_DN
Drug	Chlorambucil [305-03-3]; Down 200; 13.2uM; PC3; HT_HG-U133A	BORCS8 TLK1 BMPR2 TRIO CNTNAP2	6.43e-04	189	83	5	3788_DN
Drug	Thioguanosine [85-31-4]; Down 200; 12.6uM; MCF7; HT_HG-U133A	PAFAH1B1 KIF14 NCAPH TRIM23 RFWD3	6.58e-04	190	83	5	2619_DN
Drug	Ampyrone [83-07-8]; Down 200; 19.6uM; PC3; HT_HG-U133A	ANK3 RNF6 RNF19B CNTNAP2 SPEN	6.58e-04	190	83	5	4507_DN
Drug	Nocodazole [31430-18-9]; Up 200; 13.2uM; PC3; HT_HG-U133A	TRIO PAFAH1B1 LRRK1 AMOTL2 RUSC2	6.58e-04	190	83	5	7145_UP
Drug	Propantheline bromide [50-34-0]; Down 200; 9uM; MCF7; HT_HG-U133A	OGT RNF6 TRIO CD44 TRIM23	6.58e-04	190	83	5	3352_DN
Drug	daunorubicin HCl; Down 200; 1uM; MCF7; HT_HG-U133A	BORCS8 PAFAH1B1 KIF14 NCAPH WDR62	6.74e-04	191	83	5	7525_DN
Drug	chlorpromazine hydrochloride; Down 200; 1uM; MCF7; HT_HG-U133A	TRIO PTCRA RNF19B MECOM NOTCH2	6.74e-04	191	83	5	5214_DN
Drug	(-)-Isoproterenol hydrochloride [5984-95-2]; Down 200; 16.2uM; HL60; HT_HG-U133A	ANK2 RNF6 PTCRA ANKRD55 CHRNA5	6.74e-04	191	83	5	6149_DN
Drug	Butamben [94-25-7]; Down 200; 20.6uM; PC3; HT_HG-U133A	GLS2 RNF6 NAV3 LRRK1 TRIM23	6.74e-04	191	83	5	5792_DN
Drug	Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; HL60; HT_HG-U133A	STARD13 RNF6 PTCRA NOTCH2 TRIM23	6.90e-04	192	83	5	2450_UP
Drug	Dipyridamole [58-32-2]; Down 200; 8uM; MCF7; HT_HG-U133A	GLS2 RNF6 TRIO PAFAH1B1 RFWD3	6.90e-04	192	83	5	1517_DN
Drug	Dicumarol [66-76-2]; Up 200; 11.8uM; HL60; HT_HG-U133A	DLGAP1 CACNB4 DRD1 ANK3 IQSEC1	6.90e-04	192	83	5	2561_UP
Drug	Meclofenamic acid sodium salt monohydrate [6385-02-0]; Down 200; 11.8uM; PC3; HT_HG-U133A	ANK3 PAFAH1B1 BCL9 TIMM44 TRIM23	6.90e-04	192	83	5	7280_DN
Drug	0173570-0000 [211245-44-2]; Down 200; 1uM; PC3; HT_HG-U133A	PTCRA LRRK1 BCL3 SIX2 NOTCH2	7.07e-04	193	83	5	3693_DN
Drug	Diethylstilbestrol [56-53-1]; Up 200; 15uM; MCF7; HT_HG-U133A	TLK1 RNF6 VPS33A TRIM23 WDR62	7.07e-04	193	83	5	3429_UP
Drug	Remoxipride Hydrochloride [73220-03-8]; Down 200; 9.8uM; HL60; HT_HG-U133A	CD44 IQSEC1 LRRK1 NOTCH2 RUSC2	7.07e-04	193	83	5	3124_DN
Drug	Graveoline [485-61-0]; Up 200; 14.4uM; PC3; HT_HG-U133A	TLK1 MECOM MAP3K13 ANKRD55 TRIM23	7.07e-04	193	83	5	4276_UP
Drug	Methazolamide [554-57-4]; Up 200; 17uM; MCF7; HT_HG-U133A	GLS2 BCL9 SIX2 RUSC2 ZNF304	7.07e-04	193	83	5	3474_UP
Drug	Kaempferol [520-18-3]; Down 200; 14uM; PC3; HT_HG-U133A	LLGL2 TRIO LRRK1 NOTCH2 RUSC2	7.07e-04	193	83	5	5839_DN
Drug	5155877; Down 200; 10uM; MCF7; HT_HG-U133A	STARD13 GLS2 ARID5B IQSEC1 MECOM	7.07e-04	193	83	5	6574_DN
Drug	Progesterone [57-83-0]; Down 200; 12.8uM; PC3; HT_HG-U133A	GLS2 NAV3 SIX2 TRIM23 RUSC2	7.07e-04	193	83	5	6646_DN
Drug	phenanthridinone; Up 200; 51.2uM; MCF7; HT_HG-U133A_EA	OGT TRIO TECPR2 MECOM PUM1	7.07e-04	193	83	5	1115_UP
Drug	26-nor-25-doxylcholestanol	ANK2 ANK3	7.07e-04	11	83	2	CID000125890
Drug	AC1NSPXR	ANK2 ANK3	7.07e-04	11	83	2	CID005313815
Drug	20,25-diazacholesterol	ANK2 ANK3	7.07e-04	11	83	2	CID000009402
Drug	Tocopherol (R,S) [10191-41-0]; Down 200; 9.2uM; PC3; HT_HG-U133A	GLS2 RNF6 TECPR2 LRRK1 NOTCH2	7.23e-04	194	83	5	6616_DN
Drug	CP-645525-01 [287190-82-3]; Down 200; 10uM; MCF7; HT_HG-U133A	BORCS8 DMXL2 OGT TRIO RUSC2	7.23e-04	194	83	5	7515_DN
Drug	Simvastatin [79902-63-9]; Down 200; 9.6uM; PC3; HT_HG-U133A	GLS2 RNF6 TRIO BCL3 TRIM23	7.23e-04	194	83	5	4244_DN
Drug	Roxarsone [121-19-7]; Down 200; 15.2uM; PC3; HT_HG-U133A	RNF6 TRIO TECPR2 SIX2 TRIM23	7.23e-04	194	83	5	5051_DN
Drug	Dehydroisoandosterone 3-acetate [853-23-6]; Up 200; 12.2uM; PC3; HT_HG-U133A	BORCS8 TLK1 CNTNAP2 CD44 MAP3K13	7.23e-04	194	83	5	6673_UP
Drug	STOCK1N-35215; Down 200; 10uM; PC3; HT_HG-U133A	DMXL2 RNF6 PTCRA CNTNAP2 TRIM23	7.23e-04	194	83	5	6380_DN
Drug	Metaproterenol sulfate, orciprenaline sulfate [5874-97-5]; Down 200; 7.6uM; HL60; HT_HG-U133A	ANK2 TECPR2 VPS33A ANKRD55 CHRNA5	7.23e-04	194	83	5	2485_DN
Drug	LY 294002; Up 200; 10uM; HL60; HT_HG-U133A	TRIO TECPR2 CNTNAP2 MECOM SIX2	7.23e-04	194	83	5	2687_UP
Drug	Dichlorphenamide [120-97-8]; Down 200; 13.2uM; MCF7; HT_HG-U133A	DMXL2 TLK1 VPS33A RFWD3 ZNF304	7.23e-04	194	83	5	3366_DN
Drug	ICI182,780; Down 200; 1uM; PC3; HT_HG-U133A	CD44 TIMM44 TRRAP CHRNA5 NOTCH2	7.23e-04	194	83	5	6918_DN
Drug	Nilutamide [63612-50-0]; Down 200; 12.6uM; PC3; HT_HG-U133A	TRIO PAFAH1B1 VPS33A CNTNAP2 BCL3	7.23e-04	194	83	5	6763_DN
Drug	trifluoperazine dihydrochloride; Down 200; 10uM; MCF7; HT_HG-U133A	BORCS8 TLK1 RNF6 PTCRA PAFAH1B1	7.23e-04	194	83	5	5221_DN
Drug	NS-398; Up 200; 10uM; MCF7; HT_HG-U133A	OGT ANK3 CD44 NIPAL3 TRIM23	7.23e-04	194	83	5	6897_UP
Drug	Gabazine [105538-73-6]; Up 200; 10.8uM; HL60; HT_HG-U133A	STARD13 DMXL2 TLK1 NAV3 IQSEC1	7.23e-04	194	83	5	1316_UP
Drug	Orphenadrine hydrochloride [341-69-5]; Up 200; 13uM; PC3; HT_HG-U133A	BORCS8 NAV3 MECOM MAP3K13 WDR62	7.23e-04	194	83	5	4537_UP
Drug	Menadione [58-27-5]; Down 200; 23.2uM; PC3; HT_HG-U133A	STARD13 TRIO PAFAH1B1 NAV3 SIX2	7.23e-04	194	83	5	4662_DN
Drug	Pyrilamine maleate [59-33-6]; Up 200; 10uM; PC3; HT_HG-U133A	GLS2 TRIO PTCRA MECOM LRRK1	7.23e-04	194	83	5	5869_UP
Drug	PNU-0230031 [267429-39-0]; Down 200; 1uM; PC3; HT_HG-U133A	GLS2 RNF6 LRRK1 SIX2 RUSC2	7.23e-04	194	83	5	4291_DN
Drug	Sulindac [38194-50-2]; Up 200; 11.2uM; PC3; HT_HG-U133A	ABRAXAS2 TRIO SIX2 CHRNA5 NOTCH2	7.40e-04	195	83	5	1815_UP
Drug	pioglitazone HCl; Down 200; 10uM; PC3; HT_HG-U133A	CNTNAP2 NAV3 LRRK1 TRIM23 WDR62	7.40e-04	195	83	5	5977_DN
Disease	primary autosomal recessive microcephaly (is_implicated_in)	KIF14 NCAPH WDR62	1.05e-05	16	80	3	DOID:0070296 (is_implicated_in)
Disease	Schizophrenia	DLGAP1 DRD1 RAPGEF6 ANK3 PAFAH1B1 TET1 CNTNAP2 BCL9 TRRAP CHRNA5 PCNT	2.58e-05	883	80	11	C0036341
Disease	Microcephaly	KIF14 NCAPH TRRAP WDR62	3.37e-05	67	80	4	C0025958
Disease	response to anticonvulsant	ANK2 SYDE2 CNTNAP2 NAV3	8.58e-05	85	80	4	GO_0036277
Disease	Central hypotonia	IQSEC1 MN1	1.08e-04	6	80	2	C1842364
Disease	Leukemia, Myelocytic, Acute	TRIO CD44 MECOM MN1 NOTCH2	1.10e-04	173	80	5	C0023467
Disease	Psychotic Disorders	ANK3 TET1 BCL9 PCNT	1.67e-04	101	80	4	C0033975
Disease	Abnormality of the face	PUM1 MN1	2.58e-04	9	80	2	C4025871
Disease	trochanter bone mineral density	MECOM MEPE	3.22e-04	10	80	2	EFO_0020095
Disease	Acute Myeloid Leukemia, M1	TRIO CD44 MECOM MN1	3.78e-04	125	80	4	C0026998
Disease	Acute Myeloid Leukemia (AML-M2)	TRIO CD44 MECOM MN1	3.78e-04	125	80	4	C1879321
Disease	Global developmental delay	IQSEC1 PUM1 TRRAP MN1	4.79e-04	133	80	4	C0557874
Disease	putamen volume change measurement	SYDE2 CNTNAP2	5.55e-04	13	80	2	EFO_0021495
Disease	Nonorganic psychosis	ANK3 TET1 PCNT	8.84e-04	69	80	3	C0349204
Disease	cup-to-disc ratio measurement	ANK3 TET1 ARID5B ARHGAP9 AMOTL2 MN1	1.12e-03	430	80	6	EFO_0006939
Disease	Intellectual Disability	TRIO IQSEC1 PUM1 TRRAP MN1 WDR62	1.37e-03	447	80	6	C3714756
Disease	palmitoylcarnitine measurement	DLGAP1 CACNB4	1.47e-03	21	80	2	EFO_0021044
Disease	gastric ulcer	JUP MECOM	1.47e-03	21	80	2	EFO_0009454
Disease	Autosomal Recessive Primary Microcephaly	KIF14 WDR62	1.62e-03	22	80	2	C3711387
Disease	Ovarian Serous Adenocarcinoma	MARK1 TRRAP	1.77e-03	23	80	2	C1335177
Disease	cotinine measurement	CNTNAP2 CHRNA5	1.77e-03	23	80	2	EFO_0007813
Disease	Alzheimer disease	RAPGEF6 ANK3 RNF6 CNTNAP2 BCL3 ANKRD55	2.06e-03	485	80	6	MONDO_0004975
Disease	Neurodevelopmental Disorders	DLGAP1 ANK2 TRIO	2.09e-03	93	80	3	C1535926
Disease	Ataxia	CACNB4 PUM1	2.09e-03	25	80	2	C0004134
Disease	brain cancer (implicated_via_orthology)	LLGL2 NOTCH2	2.26e-03	26	80	2	DOID:1319 (implicated_via_orthology)
Disease	diastolic blood pressure, systolic blood pressure	ANK2 ANK3 ARID5B MECOM ARHGAP9 BCL9 WDR62	2.29e-03	670	80	7	EFO_0006335, EFO_0006336
Disease	testosterone measurement	STARD13 DLGAP1 ANK2 ANK3 PTCRA SLC38A4 ARID5B CNTNAP2 MECOM ARHGAP9	2.31e-03	1275	80	10	EFO_0004908
Disease	chronotype measurement	GLS2 ANK2 ANK3 FEZF1 PAFAH1B1 TET1 NAV3 ARHGAP9	2.69e-03	882	80	8	EFO_0008328

Protein segments in the cluster

Peptide	Gene	Start	Entry
RENHGQADHSPSMTA	BARGIN	261	Q6ZT62
SHMSSSHSFPQLARN	AMOTL2	176	Q9Y2J4
MTANRDAALSSHRHP	ESYT2	1	A0FGR8
FHPNNQESTLSHSRM	ABRAXAS2	311	Q15018
AGHSLASSHRNSMIP	CLSTN3	831	Q9BQT9
DARNHGDSPHSPDMS	ABHD11	101	Q8NFV4
ELRENHGQADHSPSM	SH3BP1	251	Q9Y3L3
HGPASQHMGNNTATV	DLGAP1	611	O14490
HAGLSSAPHHMAQRS	ANKRD55	456	Q3KP44
GSQPHSRSHSTHMNI	DMXL2	591	Q8TDJ6
NGAAMFSSHHEPRGS	DRD1	366	P21728
QRMRHSNHSTENSPI	CACNB4	436	O00305
HGMLEFLRPSSSNHS	RFWD3	131	Q6PCD5
HHEIDTASSHGPQMQ	RIC1	1181	Q4ADV7
HDHNVSSVAIMPNGD	PAFAH1B1	191	P43034
HENGNMSGTATSSPH	MECOM	991	Q03112
LLQHMAHPDAATTNG	ANK2	516	Q01484
RAGTHSMATQEFPHS	MUC16	6761	Q8WXI7
FSNLHEMQPLAHGAS	NOTCH2	2201	Q04721
MSLHSTHNRNNSGDI	KIF14	1	Q15058
HSRSTQPMHLSGEAS	PTCRA	116	Q6ISU1
QPSHAMAGHNAAAAA	NKX2-4	66	Q9H2Z4
PNSHEKMTGENVTRH	NIPAL3	156	Q6P499
AASHTRHPEGVNDQM	MAGEB10	76	Q96LZ2
AHDLSKSPDMQGSHQ	LLGL2	796	Q6P1M3
MDSFNGPSHENIITH	MEPE	451	Q9NQ76
LDTHGMRHPTANTIQ	LRRK1	1001	Q38SD2
ARDTEPQTALHGMDH	IQSEC1	276	Q6DN90
SLSHSNFNGMPHNVD	FSIP2	1801	Q5CZC0
MNQGVSSSPNLELHH	NAV3	2156	Q8IVL0
PQHQDHDSSESGMLS	GLS2	56	Q9UI32
ARFSIPSMTQHHAGR	LILRA6	81	Q6PI73
DHQPEQRGMFTVSDH	PCNT	176	O95613
HLTSRHPEAEMAQNS	JUP	461	P14923
AADRVHDSHPTNMTP	KIAA1328	311	Q86T90
GAVSNNHMHLRTGLS	LRRIQ1	86	Q96JM4
SDPNMLSNEEAGHHF	NUP155	1006	O75694
PTGDNIHAEHQVRSM	PUM1	111	Q14671
SHHPRLNMHGQDIAT	MAP3K13	651	O43283
NIHHRSSSTHNAMAP	CHRNA5	336	P30532
TAAASAHTSHPMQGR	CD44	426	P16070
NSQSGTIGPDHLDHM	BCL9	451	O00512
MNGVAGRNHSVNSHA	BMPR2	806	Q13873
SIRDHMNASAQGHSP	BORCS8	96	Q96FH0
HGMISSHITENSPNR	DNAAF9	271	Q5TEA3
QLMHHGASPNTTNVR	ANK3	451	Q12955
TANSQMGVRPHEKHD	ANK3	3766	Q12955
SARPRHQKSMSTSGH	MARK1	546	Q9P0L2
DVDHRNMANGQPHSV	CNTNAP2	1101	Q9UHC6
AALAQATPDHFHMQS	DNAAF5	191	Q86Y56
ASPMALDRHGQTAAH	BCL3	196	P20749
GLSPQSLQTSGHHRM	AUNIP	131	Q9H7T9
VSSDFGNHPTSHLMQ	OGT	561	O15294
SMHNGALDNHLSPSA	MN1	476	Q10571
EGSMATRPSNANHLS	RUSC2	876	Q8N2Y8
RSNGMNPIHPAHSTE	SYDE2	436	Q5VT97
TQRMQHNGHSLQDPS	TAS2R41	211	P59536
PDAGDQSRMHEFHSQ	STARD13	376	Q9Y3M8
SPSAHMNLSALAEGQ	RNF19B	706	Q6ZMZ0
MRSAGQTTKAHLHQP	RAPGEF6	1161	Q8TEU7
PALNMHESSQLEGHL	BMT2	131	Q1RMZ1
PRVVNHSSFHAMGAL	FEZF1	146	A0PJY2
QHLPDMHSELSNLGT	RNF6	511	Q9Y252
HSVGNLSFNNTLPMH	SLC38A4	256	Q969I6
PHRDIHNMNNGSTVV	TET1	1671	Q8NFU7
HHGQSTDHMAVSRPS	ARID5B	736	Q14865
TMNNSSSETRGHPHS	NCAPH	11	Q15003
SSSQMEDHGFPARRN	C10orf55	76	Q5SWW7
PHMRRSNSSGNLHMA	TLK1	736	Q9UKI8
RASANENSRFHPGSM	SPEN	2776	Q96T58
SAGRSQPSHPMADHS	WDR49	341	Q8IV35
AHARGHSQVPAQMEE	ZNF646	1606	O15015
HQEMVPLGDSNSHSL	TEX13C	596	A0A0J9YWL9
IAHSDKNRMTPHNLG	ARHGAP9	696	Q9BRR9
VSSEHVSGHNPMQRL	USF3	1616	Q68DE3
HSHGTQKSSQAAMPH	TECPR2	1386	O15040
HHGLQDSILNPMSAN	SIX2	271	Q9NPC8
HLQDMSHFPDRGSEN	WDR62	471	O43379
SSHNLPHGSTYQMRR	TIMM44	26	O43615
MHLLTHSSSQGQRPF	ZXDA	286	P98168
MESFPHSSSLRQHQG	ZNF304	201	Q9HCX3
LPHMQAARGSLANHT	VPS33A	341	Q96AX1
MAHTEHVPGTAENAR	TRIM23	271	P36406
SASGMIATNTRHAPH	UHRF1BP1	611	Q6BDS2
SQHDPSSNNAMLGVH	TRRAP	3021	Q9Y4A5
GTSHPHAMELQTQHN	TRIO	371	O75962
SSLNRHMRSHTGQKP	ZNF14	116	P17017
PSGHTEASAQRSHMG	UNQ9165/PRO28630	106	Q6UXU0