Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionfibroblast growth factor receptor activity

FGFR3 FGFR2 FGFR4

2.84e-075623GO:0005007
GeneOntologyMolecularFunctiontransmembrane receptor protein tyrosine kinase activity

DDR1 FGFR3 FGFR2 FGFR4

4.95e-0565624GO:0004714
GeneOntologyMolecularFunctionfibroblast growth factor binding

FGFR3 FGFR2 FGFR4

7.91e-0527623GO:0017134
GeneOntologyMolecularFunctiontransmembrane receptor protein kinase activity

DDR1 FGFR3 FGFR2 FGFR4

1.41e-0485624GO:0019199
GeneOntologyMolecularFunctiontranslation initiation factor binding

CACNA1C EIF4EBP1 EIF4G1

2.41e-0439623GO:0031369
GeneOntologyMolecularFunctionheparin binding

FN1 PCOLCE2 FGFR2 FGFR4 LGR6

3.24e-04192625GO:0008201
GeneOntologyMolecularFunctioneukaryotic initiation factor 4E binding

EIF4EBP1 EIF4G1

5.12e-0411622GO:0008190
GeneOntologyMolecularFunctionprotein tyrosine kinase activity

DDR1 FGFR3 FGFR2 FGFR4

1.07e-03145624GO:0004713
GeneOntologyMolecularFunctionglycosaminoglycan binding

FN1 PCOLCE2 FGFR2 FGFR4 LGR6

1.45e-03268625GO:0005539
GeneOntologyMolecularFunctioncollagen binding

DDR1 FN1 PCOLCE2

2.05e-0381623GO:0005518
GeneOntologyBiologicalProcessrespiratory tube development

DLG5 EIF4G1 FGFR3 FGFR2 FGFR4 HECA CIC

1.56e-05273617GO:0030323
GeneOntologyBiologicalProcesspositive regulation of secretion by cell

CACNA1C MYOM1 SEC24A TMF1 PTPN23 FGFR4 STAM RUNX1

2.40e-05404618GO:1903532
GeneOntologyBiologicalProcessfibroblast growth factor receptor apoptotic signaling pathway

FGFR3 FGFR2

2.58e-053612GO:1902178
GeneOntologyBiologicalProcesscochlea development

TBX18 CECR2 DVL1 FGFR3

3.18e-0561614GO:0090102
GeneOntologyBiologicalProcesspositive regulation of secretion

CACNA1C MYOM1 SEC24A TMF1 PTPN23 FGFR4 STAM RUNX1

4.06e-05435618GO:0051047
GeneOntologyBiologicalProcessalveolar secondary septum development

FGFR3 FGFR4

5.14e-054612GO:0061144
GeneOntologyBiologicalProcessgrowth

CACNA1C DDR1 TENM4 ATN1 FN1 EIF4G1 DVL1 DACT3 FGFR3 FGFR2 LGR6 BCAR1 RUNX1

5.29e-0512356113GO:0040007
GeneOntologyBiologicalProcesscell fate commitment

EBF2 TBX18 TENM4 CHD3 FGFR3 FGFR2 RUNX1

6.09e-05338617GO:0045165
GeneOntologyBiologicalProcesslung alveolus development

FGFR3 FGFR2 FGFR4 CIC

7.19e-0575614GO:0048286
GeneOntologyBiologicalProcessanatomical structure formation involved in morphogenesis

SLC25A46 TBX18 HOXB1 COL12A1 TENM4 FN1 MYOM1 SLC34A1 CECR2 DVL1 TMF1 FGFR2 FGFR4 RUNX1

8.46e-0514836114GO:0048646
GeneOntologyBiologicalProcessubiquitin-dependent protein catabolic process

ZSWIM8 ARRDC1 DTL DVL1 ZNRF1 PTPN23 STAM SH3RF3 FAF1

1.03e-04640619GO:0006511
GeneOntologyBiologicalProcessmodification-dependent protein catabolic process

ZSWIM8 ARRDC1 DTL DVL1 ZNRF1 PTPN23 STAM SH3RF3 FAF1

1.18e-04651619GO:0019941
GeneOntologyBiologicalProcessproteolysis involved in protein catabolic process

ZSWIM8 ARRDC1 DTL DVL1 TMF1 ZNRF1 PTPN23 STAM SH3RF3 FAF1

1.24e-048126110GO:0051603
GeneOntologyBiologicalProcessmodification-dependent macromolecule catabolic process

ZSWIM8 ARRDC1 DTL DVL1 ZNRF1 PTPN23 STAM SH3RF3 FAF1

1.25e-04656619GO:0043632
GeneOntologyBiologicalProcesslung development

DLG5 EIF4G1 FGFR3 FGFR2 FGFR4 CIC

1.42e-04269616GO:0030324
GeneOntologyBiologicalProcesstube development

TBX18 DDR1 DLG5 FN1 CECR2 EIF4G1 DVL1 FGFR3 FGFR2 FGFR4 RUNX1 HECA CIC

1.90e-0414026113GO:0035295
GeneOntologyBiologicalProcessear development

TBX18 DDR1 CECR2 DVL1 FGFR3 FGFR2

1.94e-04285616GO:0043583
GeneOntologyBiologicalProcessembryonic morphogenesis

CACNA1C TBX18 HOXB1 COL12A1 TENM4 FN1 CECR2 DVL1 FGFR2

2.33e-04713619GO:0048598
GeneOntologyBiologicalProcessrespiratory system development

DLG5 EIF4G1 FGFR3 FGFR2 FGFR4 CIC

2.79e-04305616GO:0060541
GeneOntologyBiologicalProcessregulation of secretion by cell

CACNA1C MYOM1 SEC24A DVL1 TMF1 PTPN23 FGFR4 STAM RUNX1

3.06e-04740619GO:1903530
GeneOntologyBiologicalProcessdevelopmental growth

CACNA1C DDR1 TENM4 ATN1 FN1 DVL1 FGFR3 FGFR2 LGR6 RUNX1

3.13e-049116110GO:0048589
GeneOntologyBiologicalProcessprotein catabolic process

ZSWIM8 ARRDC1 TPP1 DTL DVL1 TMF1 ZNRF1 PTPN23 STAM SH3RF3 FAF1

3.80e-0411156111GO:0030163
GeneOntologyBiologicalProcessregulation of phosphate transport

SLC34A1 FGFR4

3.81e-0410612GO:0010966
GeneOntologyBiologicalProcessgastrulation

COL12A1 TENM4 FN1 DVL1 FGFR2

4.08e-04212615GO:0007369
GeneOntologyBiologicalProcessregulation of growth

CACNA1C DDR1 FN1 EIF4G1 DACT3 FGFR3 FGFR2 BCAR1 RUNX1

4.37e-04777619GO:0040008
GeneOntologyBiologicalProcessmorphogenesis of an epithelium

TBX18 DDR1 DLG5 CECR2 DVL1 FGFR3 FGFR2 RUNX1

4.56e-04619618GO:0002009
GeneOntologyBiologicalProcesscanonical Wnt signaling pathway

TBX18 DVL1 DACT3 FGFR3 FGFR2 LGR6

5.29e-04344616GO:0060070
GeneOntologyBiologicalProcessregulation of secretion

CACNA1C MYOM1 SEC24A DVL1 TMF1 PTPN23 FGFR4 STAM RUNX1

5.44e-04801619GO:0051046
GeneOntologyBiologicalProcesspositive regulation of cell proliferation in bone marrow

FGFR3 FGFR2

5.57e-0412612GO:0071864
GeneOntologyBiologicalProcessaxon development

SLC25A46 DDR1 LHX4 FN1 DVL1 FGFR3 FGFR2 LGR6

5.80e-04642618GO:0061564
GeneOntologyBiologicalProcesslung saccule development

FGFR3 FGFR4

6.57e-0413612GO:0060430
GeneOntologyBiologicalProcessresponse to sodium phosphate

SLC34A1 FGFR3

6.57e-0413612GO:1904383
GeneOntologyBiologicalProcesscentral nervous system development

SLC25A46 HOXB1 DLG5 TENM4 LHX4 ATN1 TPP1 FGFR3 FGFR2 RUNX1 CIC

6.89e-0411976111GO:0007417
GeneOntologyBiologicalProcesscardiac cell fate commitment

TBX18 TENM4

7.65e-0414612GO:0060911
GeneOntologyBiologicalProcessresponse to mercury ion

FN1 SLC34A1

7.65e-0414612GO:0046689
GeneOntologyBiologicalProcesspositive regulation of phospholipase activity

FGFR3 FGFR2

7.65e-0414612GO:0010518
GeneOntologyBiologicalProcesslung epithelium development

FGFR3 FGFR2 FGFR4

7.84e-0461613GO:0060428
GeneOntologyBiologicalProcessprotein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

PTPN23 STAM

8.81e-0415612GO:0043328
GeneOntologyBiologicalProcessinner ear development

TBX18 CECR2 DVL1 FGFR3 FGFR2

9.07e-04253615GO:0048839
GeneOntologyBiologicalProcessorgan growth

CACNA1C TENM4 FGFR3 FGFR2 RUNX1

9.56e-04256615GO:0035265
GeneOntologyBiologicalProcessperipheral nervous system neuron development

SLC25A46 RUNX1

1.01e-0316612GO:0048935
GeneOntologyBiologicalProcessperipheral nervous system neuron differentiation

SLC25A46 RUNX1

1.01e-0316612GO:0048934
GeneOntologyBiologicalProcessregulation of cell proliferation in bone marrow

FGFR3 FGFR2

1.01e-0316612GO:0071863
GeneOntologyBiologicalProcessneuron development

SLC25A46 DDR1 DLG5 TENM4 LHX4 FN1 CECR2 DVL1 FGFR3 FGFR2 LGR6 RUNX1

1.04e-0314636112GO:0048666
DomainFGF_rcpt_fam

FGFR3 FGFR2 FGFR4

1.32e-074613IPR016248
DomainDVL-1

DVL1P1 DVL1

1.05e-052612IPR008340
DomainDishevelled_fam

DVL1P1 DVL1

6.27e-054612IPR008339
DomainDishevelled

DVL1P1 DVL1

6.27e-054612PF02377
DomainDishevelled_protein_dom

DVL1P1 DVL1

6.27e-054612IPR003351
DomainNUT

NUTM2F NUTM2G

1.04e-045612IPR024310
DomainNUT_N

NUTM2F NUTM2G

1.04e-045612IPR024309
DomainNUT

NUTM2F NUTM2G

1.04e-045612PF12881
DomainTyrKc

DDR1 FGFR3 FGFR2 FGFR4

1.96e-0488614SM00219
DomainTyr_kinase_cat_dom

DDR1 FGFR3 FGFR2 FGFR4

1.96e-0488614IPR020635
DomainDIX

DVL1P1 DVL1

2.18e-047612PF00778
DomainDIX

DVL1P1 DVL1

2.18e-047612IPR001158
DomainDIX

DVL1P1 DVL1

2.18e-047612PS50841
DomainDAX

DVL1P1 DVL1

2.18e-047612SM00021
DomainPROTEIN_KINASE_TYR

DDR1 FGFR3 FGFR2 FGFR4

2.84e-0497614PS00109
DomainTyr_kinase_AS

DDR1 FGFR3 FGFR2 FGFR4

2.84e-0497614IPR008266
DomainSH3

DLG5 PPP1R13B STAM BCAR1 SH3RF3

6.94e-04216615SM00326
DomainSH3

DLG5 PPP1R13B STAM BCAR1 SH3RF3

6.94e-04216615PS50002
DomainSH3_domain

DLG5 PPP1R13B STAM BCAR1 SH3RF3

7.54e-04220615IPR001452
DomainPkinase_Tyr

DDR1 FGFR3 FGFR2 FGFR4

8.36e-04129614PF07714
DomainSer-Thr/Tyr_kinase_cat_dom

DDR1 FGFR3 FGFR2 FGFR4

1.07e-03138614IPR001245
DomainSH3_1

PPP1R13B STAM BCAR1 SH3RF3

2.03e-03164614PF00018
DomainDEP

DVL1P1 DVL1

2.32e-0322612PF00610
DomainDEP

DVL1P1 DVL1

2.32e-0322612PS50186
DomainDEP

DVL1P1 DVL1

2.32e-0322612SM00049
DomainDEP_dom

DVL1P1 DVL1

2.54e-0323612IPR000591
DomainIg_I-set

MYOM1 FGFR3 FGFR2 FGFR4

3.45e-03190614IPR013098
DomainI-set

MYOM1 FGFR3 FGFR2 FGFR4

3.45e-03190614PF07679
Domain-

EBF2 COL12A1 FN1 MYOM1 FGFR3 FGFR2 FGFR4

5.70e-036636172.60.40.10
DomainIGc2

MYOM1 FGFR3 FGFR2 FGFR4

7.28e-03235614SM00408
DomainIg_sub2

MYOM1 FGFR3 FGFR2 FGFR4

7.28e-03235614IPR003598
DomainIg-like_fold

EBF2 COL12A1 FN1 MYOM1 FGFR3 FGFR2 FGFR4

7.95e-03706617IPR013783
PathwayWP_REGULATION_OF_ACTIN_CYTOSKELETON

FN1 FGFR3 FGFR2 FGFR4 BCAR1 PIP4K2C

1.11e-05150486M39520
PathwayWP_REGULATION_OF_ACTIN_CYTOSKELETON

FN1 FGFR3 FGFR2 FGFR4 BCAR1 PIP4K2C

1.20e-05152486MM15834
PathwayWP_FGF23_SIGNALING_IN_HYPOPHOSPHATEMIC_RICKETS_AND_RELATED_DISORDERS

SLC34A1 FGFR3 FGFR2

6.25e-0523483M39862
PathwayKEGG_REGULATION_OF_ACTIN_CYTOSKELETON

FN1 FGFR3 FGFR2 FGFR4 BCAR1 PIP4K2C

8.02e-05213486M18306
PathwayKEGG_MEDICUS_REFERENCE_REGULATION_OF_GF_RTK_RAS_ERK_SIGNALING_UBIQUITINATION_OF_RTK_BY_CBL

FGFR3 FGFR2 FGFR4

8.08e-0525483M47934
PathwayKEGG_MEDICUS_REFERENCE_FGF_FGFR_PI3K_SIGNALING_PATHWAY

FGFR3 FGFR2 FGFR4

1.56e-0431483M47396
PathwayKEGG_MEDICUS_REFERENCE_FGF_FGFR_RAS_ERK_SIGNALING_PATHWAY

FGFR3 FGFR2 FGFR4

2.25e-0435483M47379
PathwayWP_NEURAL_CREST_DIFFERENTIATION

HOXB1 DVL1 FGFR3 FGFR2

3.25e-0497484MM15926
PathwayWP_NEURAL_CREST_DIFFERENTIATION

HOXB1 DVL1 FGFR3 FGFR2

3.79e-04101484M39448
PathwayREACTOME_IRS_MEDIATED_SIGNALLING

FGFR3 FGFR2 FGFR4

5.75e-0448483M26916
PathwayWP_BURN_WOUND_HEALING

FN1 FGFR3 FGFR2 FGFR4

5.80e-04113484M42571
PathwayWP_VEGFAVEGFR2_SIGNALING

FN1 UBAP2L TPP1 EIF4G1 STAM BCAR1 FAF1

5.92e-04431487M39729
PathwayREACTOME_INTRACELLULAR_SIGNALING_BY_SECOND_MESSENGERS

ATN1 CHD3 FGFR3 FGFR2 FGFR4 PIP4K2C

6.39e-04313486M27867
PathwayWP_ESC_PLURIPOTENCY_PATHWAYS

DVL1 FGFR3 FGFR2 FGFR4

6.41e-04116484MM15863
PathwayWP_OSTEOARTHRITIC_CHONDROCYTE_HYPERTROPHY

FGFR3 FGFR2 FGFR4

6.49e-0450483M48087
PathwayWP_PLEURAL_MESOTHELIOMA

FN1 EIF4EBP1 EIF4G1 DVL1 FGFR3 FGFR2 FGFR4

6.61e-04439487M42563
PathwayWP_EMBRYONIC_STEM_CELL_PLURIPOTENCY_PATHWAYS

DVL1 FGFR3 FGFR2 FGFR4

6.62e-04117484M39530
PathwayREACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK

FGFR3 FGFR2 FGFR4 PIP4K2C

6.83e-04118484M713
PathwayREACTOME_SIGNALING_BY_TYPE_1_INSULIN_LIKE_GROWTH_FACTOR_1_RECEPTOR_IGF1R

FGFR3 FGFR2 FGFR4

8.14e-0454483M27168
PathwayREACTOME_INSULIN_RECEPTOR_SIGNALLING_CASCADE

FGFR3 FGFR2 FGFR4

8.14e-0454483M620
PathwayPID_FGF_PATHWAY

FGFR3 FGFR2 FGFR4

8.58e-0455483M276
PathwayKEGG_MEDICUS_REFERENCE_RTK_PLCG_ITPR_SIGNALING_PATHWAY

FGFR3 FGFR2 FGFR4

8.58e-0455483M47952
PathwayREACTOME_P130CAS_LINKAGE_TO_MAPK_SIGNALING_FOR_INTEGRINS

FN1 BCAR1

1.16e-0315482M12101
PathwayREACTOME_P130CAS_LINKAGE_TO_MAPK_SIGNALING_FOR_INTEGRINS

FN1 BCAR1

1.16e-0315482MM14961
PathwayREACTOME_SIGNALING_BY_FGFR_IN_DISEASE

FGFR3 FGFR2 FGFR4

1.27e-0363483M635
PathwayREACTOME_SIGNALING_BY_MET

RANBP10 FN1 STAM

1.52e-0367483MM15345
PathwayWP_INTERACTIONS_BETWEEN_LOXL4_AND_OXIDATIVE_STRESS_PATHWAY

DDR1 FN1

1.68e-0318482M39586
PathwayWP_MIR5093P_ALTERATION_OF_YAP1ECM_AXIS

FN1 BCAR1

1.68e-0318482M39421
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

DDR1 PHYKPL COL12A1 FN1 PCOLCE2

1.78e-03258485MM14572
PathwayREACTOME_SIGNALING_BY_RECEPTOR_TYROSINE_KINASES

RANBP10 FN1 FGFR3 FGFR2 FGFR4 STAM BCAR1

2.01e-03532487M27870
PathwayWP_HEAD_AND_NECK_SQUAMOUS_CELL_CARCINOMA

EIF4EBP1 FGFR3 FGFR2

2.03e-0374483M39857
PathwayPID_AVB3_INTEGRIN_PATHWAY

COL12A1 FN1 BCAR1

2.03e-0374483M160
Pubmed

CDC42 is required for epicardial and pro-epicardial development by mediating FGF receptor trafficking to the plasma membrane.

TBX18 FGFR3 FGFR2 FGFR4

1.40e-081564428465335
Pubmed

Elevated fibroblast growth factor 23 exerts its effects on placenta and regulates vitamin D metabolism in pregnancy of Hyp mice.

SLC34A1 FGFR3 FGFR2 FGFR4

1.87e-081664424470103
Pubmed

Responsiveness of developing dental tissues to fibroblast growth factors: expression of splicing alternatives of FGFR1, -2, -3, and of FGFR4; and stimulation of cell proliferation by FGF-2, -4, -8, and -9.

FGFR3 FGFR2 FGFR4

2.37e-0846439664689
Pubmed

Differential expression of the fibroblast growth factor receptor (FGFR) multigene family in normal human adult tissues.

FGFR3 FGFR2 FGFR4

2.37e-0846439212826
Pubmed

Expression of fibroblast growth factor receptor family members is associated with prognosis in early stage cervical cancer patients.

FGFR3 FGFR2 FGFR4

2.37e-08464327154171
Pubmed

Amplification of FRS2 and activation of FGFR/FRS2 signaling pathway in high-grade liposarcoma.

FGFR3 FGFR2 FGFR4

2.37e-08464323393200
Pubmed

Immunolocalization of fibroblast growth factor receptors in normal and wounded human skin.

FGFR3 FGFR2 FGFR4

2.37e-08464312373339
Pubmed

FGFR1-4 RNA-Based Gene Alteration and Expression Analysis in Squamous Non-Small Cell Lung Cancer.

FGFR3 FGFR2 FGFR4

2.37e-08464336142417
Pubmed

Immunohistochemical detection of fibroblast growth factor receptors in normal endocrine cells and related tumors of the digestive system.

FGFR3 FGFR2 FGFR4

2.37e-08464311759058
Pubmed

The FGF system has a key role in regulating vascular integrity.

FGFR3 FGFR2 FGFR4

2.37e-08464318776942
Pubmed

RNAi-based conditional gene knockdown in mice using a U6 promoter driven vector.

FGFR3 FGFR2 FGFR4

2.37e-08464317304337
Pubmed

Expression of basic fibroblast growth factor and its receptors in human ovarian follicles from adults and fetuses.

FGFR3 FGFR2 FGFR4

2.37e-08464316210019
Pubmed

Differential expression of fibroblast growth factor receptors in the developing murine choroid plexus.

FGFR3 FGFR2 FGFR4

2.37e-08464312644244
Pubmed

FGF8 is required for cell survival at distinct stages of nephrogenesis and for regulation of gene expression in nascent nephrons.

SLC34A1 FGFR3 FGFR2 FGFR4

3.96e-081964416049112
Pubmed

Efficient regulation of branching morphogenesis via fibroblast growth factor receptor 2c in early-stage embryonic mouse salivary glands.

FGFR3 FGFR2 FGFR4

5.93e-08564327206683
Pubmed

Conditional knockdown of Fgfr2 in mice using Cre-LoxP induced RNA interference.

FGFR3 FGFR2 FGFR4

5.93e-08564315987787
Pubmed

The expression profiles of fibroblast growth factor 9 and its receptors in developing mice testes.

FGFR3 FGFR2 FGFR4

5.93e-08564327078042
Pubmed

Different intracellular trafficking of FGF1 endocytosed by the four homologous FGF receptors.

FGFR3 FGFR2 FGFR4

5.93e-08564316091423
Pubmed

FGF-dependent regulation of VEGF receptor 2 expression in mice.

FGFR3 FGFR2 FGFR4

5.93e-08564321633168
Pubmed

Expression of fibroblast growth factor receptors in peri-implantation mouse embryos.

FGFR3 FGFR2 FGFR4

5.93e-0856439771645
Pubmed

Persistent fibroblast growth factor 23 signalling in the parathyroid glands for secondary hyperparathyroidism in mice with chronic kidney disease.

FGFR3 FGFR2 FGFR4

5.93e-08564328094278
Pubmed

Overlapping expression and redundant activation of mesenchymal fibroblast growth factor (FGF) receptors by alternatively spliced FGF-8 ligands.

FGFR3 FGFR2 FGFR4

5.93e-0856439013630
Pubmed

The mouse Fgfrl1 gene coding for a novel FGF receptor-like protein.

FGFR3 FGFR2 FGFR4

5.93e-08564311566361
Pubmed

Fgfr1 and Fgfr2 have distinct differentiation- and proliferation-related roles in the developing mouse skull vault.

FGFR3 FGFR2 FGFR4

1.18e-07664310572038
Pubmed

FGF2 concentration regulates the generation of neurons and glia from multipotent cortical stem cells.

FGFR3 FGFR2 FGFR4

1.18e-0766439010207
Pubmed

Trans-activation of EphA4 and FGF receptors mediated by direct interactions between their cytoplasmic domains.

FGFR3 FGFR2 FGFR4

1.18e-07664316365308
Pubmed

Regulation of fibroblast growth factor-23 signaling by klotho.

FGFR3 FGFR2 FGFR4

1.18e-07664316436388
Pubmed

Neuron-derived FGF9 is essential for scaffold formation of Bergmann radial fibers and migration of granule neurons in the cerebellum.

FGFR3 FGFR2 FGFR4

1.18e-07664319232523
Pubmed

Central role of the proximal tubular αKlotho/FGF receptor complex in FGF23-regulated phosphate and vitamin D metabolism.

FGFR3 FGFR2 FGFR4

1.18e-07664329720668
Pubmed

FGF23 decreases renal NaPi-2a and NaPi-2c expression and induces hypophosphatemia in vivo predominantly via FGF receptor 1.

SLC34A1 FGFR3 FGFR4

1.18e-07664319515808
Pubmed

Evidence that the novel receptor FGFRL1 signals indirectly via FGFR1.

FGFR3 FGFR2 FGFR4

1.18e-07664324026051
Pubmed

FGF15 promotes neurogenesis and opposes FGF8 function during neocortical development.

MEST FGFR3 FGFR2 FGFR4

1.28e-072564418625063
Pubmed

FGF as a target-derived chemoattractant for developing motor axons genetically programmed by the LIM code.

FGFR3 FGFR2 FGFR4

2.07e-07764316772167
Pubmed

Activin and basic fibroblast growth factor regulate neurogenesis of murine embryonal carcinoma cells.

FGFR3 FGFR2 FGFR4

2.07e-0776438959336
Pubmed

Expression patterns of FGF receptors in the developing mammalian cochlea.

FGFR3 FGFR2 FGFR4

2.07e-07764320131355
Pubmed

Beta1 integrins regulate chondrocyte rotation, G1 progression, and cytokinesis.

FN1 FGFR3 FGFR2 BCAR1

2.39e-072964414522949
Pubmed

betaKlotho is required for fibroblast growth factor (FGF) 21 signaling through FGF receptor (FGFR) 1c and FGFR3c.

FGFR3 FGFR2 FGFR4

3.31e-07864318187602
Pubmed

Tissue-specific expression of betaKlotho and fibroblast growth factor (FGF) receptor isoforms determines metabolic activity of FGF19 and FGF21.

FGFR3 FGFR2 FGFR4

3.31e-07864317623664
Pubmed

Syndecan-4 dependent FGF stimulation of mouse vibrissae growth.

FGFR3 FGFR2 FGFR4

3.31e-07864316989989
Pubmed

Expression of Fgf receptors 1, 2, and 3 in the developing mid- and hindbrain of the mouse.

FGFR3 FGFR2 FGFR4

4.95e-07964315830353
Pubmed

Dynamic activation of Wnt, Fgf, and Hh signaling during soft palate development.

FGFR3 FGFR2 FGFR4

4.95e-07964331613912
Pubmed

Integration of FGF and TWIST in calvarial bone and suture development.

FGFR3 FGFR2 FGFR4

4.95e-07964310751173
Pubmed

Interplay of Endosomal pH and Ligand Occupancy in Integrin α5β1 Ubiquitination, Endocytic Sorting, and Cell Migration.

FN1 PTPN23 STAM

4.95e-07964326456826
Pubmed

The expression of fibroblast growth factors and their receptors in the embryonic and neonatal mouse inner ear.

FGFR3 FGFR2 FGFR4

4.95e-07964311335076
Pubmed

Fgf9 induces proliferation and nuclear localization of FGFR2 in Sertoli precursors during male sex determination.

FGFR3 FGFR2 FGFR4

4.95e-07964315229180
Pubmed

Laminar patterning in the developing neocortex by temporally coordinated fibroblast growth factor signaling.

FGFR3 FGFR2 FGFR4

7.07e-071064315470137
Pubmed

Regulation of external genitalia development by concerted actions of FGF ligands and FGF receptors.

FGFR3 FGFR2 FGFR4

7.07e-071064315340846
Pubmed

Targeting promiscuous heterodimerization overcomes innate resistance to ERBB2 dimerization inhibitors in breast cancer.

DDR1 FGFR3 FGFR2 FGFR4

9.06e-074064430898150
Pubmed

Fibroblast growth factor signalling in the hair growth cycle: expression of the fibroblast growth factor receptor and ligand genes in the murine hair follicle.

FGFR3 FGFR2 FGFR4

9.70e-07116438901049
Pubmed

Fgf20 is required for sensory epithelial specification in the developing cochlea.

FGFR3 FGFR2 FGFR4

9.70e-071164318524904
Pubmed

Dlg-1 Interacts With and Regulates the Activities of Fibroblast Growth Factor Receptors and EphA2 in the Mouse Lens.

FGFR3 FGFR2 FGFR4

9.70e-071164326906157
Pubmed

The murine gene, Traube, is essential for the growth of preimplantation embryos.

FGFR3 FGFR2 FGFR4

9.70e-071164311071758
Pubmed

A local source of FGF initiates development of the unmyelinated lineage of sensory neurons.

FGFR3 FGFR2 FGFR4 RUNX1

1.11e-064264424198358
Pubmed

Integrated proteogenetic analysis reveals the landscape of a mitochondrial-autophagosome synapse during PARK2-dependent mitophagy.

SLC25A46 UBAP2L SEC24A STAM FAF1

1.13e-069964531723608
Pubmed

Immunohistochemical study of genesis of the mouse oral vestibule.

FGFR3 FGFR2 FGFR4

1.29e-061264314964469
Pubmed

Temporal and spatial gradients of Fgf8 and Fgf17 regulate proliferation and differentiation of midline cerebellar structures.

FGFR3 FGFR2 FGFR4

1.29e-061264310751172
Pubmed

Variant heparan sulfates synthesized in developing mouse brain differentially regulate FGF signaling.

FGFR3 FGFR2 FGFR4

1.29e-061264312460940
Pubmed

The roles of FGF signaling in germ cell migration in the mouse.

FGFR3 FGFR2 FGFR4

1.29e-061264316291796
Pubmed

Mapping of murine fibroblast growth factor receptors refines regions of homology between mouse and human chromosomes.

FGFR3 FGFR2 FGFR4

1.29e-06126437959747
Pubmed

A quantitative method for evaluation of FGF family and FGF receptor family gene expression by RT-PCR.

FGFR3 FGFR2 FGFR4

1.68e-06136439385055
Pubmed

A point mutation in Fgf9 impedes joint interzone formation leading to multiple synostoses syndrome.

FGFR3 FGFR2 FGFR4

1.68e-061364328169396
Pubmed

Testis Determination Requires a Specific FGFR2 Isoform to Repress FOXL2.

FGFR3 FGFR2 FGFR4

1.68e-061364328938467
Pubmed

Expression of the fibroblast growth factor family and their receptor family genes during mouse brain development.

FGFR3 FGFR2 FGFR4

1.68e-06136438883961
Pubmed

Receptor specificity of the fibroblast growth factor family.

FGFR3 FGFR2 FGFR4

1.68e-06136438663044
Pubmed

FGF8 is essential for formation of the ductal system in the male reproductive tract.

FGFR3 FGFR2 FGFR4

2.66e-061564322110055
Pubmed

Sprouty proteins regulate ureteric branching by coordinating reciprocal epithelial Wnt11, mesenchymal Gdnf and stromal Fgf7 signalling during kidney development.

FGFR3 FGFR2 FGFR4

3.27e-061664315201220
Pubmed

Embryonic submandibular gland morphogenesis: stage-specific protein localization of FGFs, BMPs, Pax6 and Pax9 in normal mice and abnormal SMG phenotypes in FgfR2-IIIc(+/Delta), BMP7(-/-) and Pax6(-/-) mice.

FGFR3 FGFR2 FGFR4

3.27e-061664311731698
Pubmed

Structural insights into the allosteric effects of 4EBP1 on the eukaryotic translation initiation factor eIF4E.

EIF4EBP1 EIF4G1

3.33e-06264222178476
Pubmed

Fibroblast growth factor receptor 3 is a negative regulator of bone growth.

FGFR3 FGFR2

3.33e-0626428601314
Pubmed

Superficial acral calcified chondroid mesenchymal neoplasm harboring an FN1::FGFR2 fusion and review of the literature.

FN1 FGFR2

3.33e-06264238328983
Pubmed

Genetic variants in FGFR2 and FGFR4 genes and skin cancer risk in the Nurses' Health Study.

FGFR2 FGFR4

3.33e-06264219500394
Pubmed

Activation of FGF receptors by mutations in the transmembrane domain.

FGFR3 FGFR2

3.33e-0626429136983
Pubmed

Novel targetable FGFR2 and FGFR3 alterations in glioblastoma associate with aggressive phenotype and distinct gene expression programs.

FGFR3 FGFR2

3.33e-06264233853673
Pubmed

Prognostic impact of FGFR2/3 alterations in patients with biliary tract cancers receiving systemic chemotherapy: the BITCOIN study.

FGFR3 FGFR2

3.33e-06264235303508
Pubmed

Early mandibular morphological differences in patients with FGFR2 and FGFR3-related syndromic craniosynostoses: A 3D comparative study.

FGFR3 FGFR2

3.33e-06264232822871
Pubmed

Rapidly acquired resistance to EGFR tyrosine kinase inhibitors in NSCLC cell lines through de-repression of FGFR2 and FGFR3 expression.

FGFR3 FGFR2

3.33e-06264221152424
Pubmed

FGFR-3 and FGFR-4 function cooperatively to direct alveogenesis in the murine lung.

FGFR3 FGFR4

3.33e-0626429716527
Pubmed

Fibroblast growth factor receptors control epithelial-mesenchymal interactions necessary for alveolar elastogenesis.

FGFR3 FGFR4

3.33e-06264220093646
Pubmed

Association of FGFR3 and FGFR4 gene polymorphisms with breast cancer in Chinese women of Heilongjiang province.

FGFR3 FGFR4

3.33e-06264226431494
Pubmed

Altered expressions of fibroblast growth factor receptors and alveolarization in neonatal mice exposed to 85% oxygen.

FGFR3 FGFR4

3.33e-06264217957151
Pubmed

Mutations in fibroblast growth factor receptor 2 and fibroblast growth factor receptor 3 genes associated with human gastric and colorectal cancers.

FGFR3 FGFR2

3.33e-06264211325814
Pubmed

Germline mutations in FGF receptors and medulloblastomas.

FGFR3 FGFR2

3.33e-06264223325524
Pubmed

Human homologue sequences to the Drosophila dishevelled segment-polarity gene are deleted in the DiGeorge syndrome.

DVL1P1 DVL1

3.33e-0626428644734
Pubmed

Inhibitor-sensitive FGFR2 and FGFR3 mutations in lung squamous cell carcinoma.

FGFR3 FGFR2

3.33e-06264223786770
Pubmed

Molecular mechanism of the dual activity of 4EGI-1: Dissociating eIF4G from eIF4E but stabilizing the binding of unphosphorylated 4E-BP1.

EIF4EBP1 EIF4G1

3.33e-06264226170285
Pubmed

FGF8 Signaling Alters the Osteogenic Cell Fate in the Hard Palate.

FGFR3 FGFR2 FGFR4

3.97e-061764329342370
Pubmed

Fgf21 regulates T-cell development in the neonatal and juvenile thymus.

FGFR3 FGFR2 FGFR4

4.75e-061864328336912
Pubmed

Feto-maternal cholesterol transport regulated by β-Klotho-FGF15 axis is essential for fetal growth.

FGFR3 FGFR2 FGFR4

5.64e-061964337541847
Pubmed

TGF-β signaling and Creb5 cooperatively regulate Fgf18 to control pharyngeal muscle development.

FGFR3 FGFR2 FGFR4

6.63e-062064336542062
Pubmed

Phospholipase C-gamma as a signal-transducing element.

FGFR3 FGFR2 FGFR4

7.72e-062164310579907
Pubmed

MT1-MMP inactivates ADAM9 to regulate FGFR2 signaling and calvarial osteogenesis.

FGFR3 FGFR2 FGFR4

7.72e-062164322632802
Pubmed

Expression of members of the Fgf family and their receptors during midfacial development.

FGFR3 FGFR2 FGFR4

8.93e-062264311165488
Pubmed

Fgfr1 regulates patterning of the pharyngeal region.

HOXB1 FGFR3 FGFR2

8.93e-062264312514106
Pubmed

FGF9 suppresses meiosis and promotes male germ cell fate in mice.

FGFR3 FGFR2 FGFR4

8.93e-062264320833365
Pubmed

Epicardial function of canonical Wnt-, Hedgehog-, Fgfr1/2-, and Pdgfra-signalling.

TBX18 FN1 FGFR2

8.93e-062264324000064
Pubmed

Transient Redirection of SVZ Stem Cells to Oligodendrogenesis by FGFR3 Activation Promotes Remyelination.

FGFR3 FGFR2

9.99e-06364231189094
Pubmed

Mitosis-related phosphorylation of the eukaryotic translation suppressor 4E-BP1 and its interaction with eukaryotic translation initiation factor 4E (eIF4E).

EIF4EBP1 EIF4G1

9.99e-06364231201269
Pubmed

Different clinical significance of FGFR1-4 expression between diffuse-type and intestinal-type gastric cancer.

FGFR2 FGFR4

9.99e-06364228056982
Pubmed

The cell surface receptor FGFRL1 forms constitutive dimers that promote cell adhesion.

FGFR3 FGFR4

9.99e-06364218061161
Pubmed

The melanoma-associated antigen A3 mediates fibronectin-controlled cancer progression and metastasis.

FN1 FGFR2

9.99e-06364218829569
InteractionSEC24B interactions

SLC25A46 DDR1 SEC24A FGFR3 FGFR2 FGFR4 STAM BCAR1

7.93e-07240638int:SEC24B
InteractionFGF6 interactions

FGFR3 FGFR2 FGFR4

1.01e-067633int:FGF6
InteractionFGF18 interactions

FGFR3 FGFR2 FGFR4

1.01e-067633int:FGF18
InteractionFGF5 interactions

FGFR3 FGFR2 FGFR4

1.61e-068633int:FGF5
InteractionFGF23 interactions

FGFR3 FGFR2 FGFR4

1.61e-068633int:FGF23
InteractionHGS interactions

MEST ATN1 PTPN23 FGFR3 FGFR2 FGFR4 STAM RUNX1 NUTM2F CIC

4.73e-065236310int:HGS
InteractionKLB interactions

FGFR3 FGFR2 FGFR4

6.28e-0612633int:KLB
InteractionKL interactions

FGFR3 FGFR2 FGFR4

1.03e-0514633int:KL
InteractionYWHAB interactions

DLG5 FN1 SEC24A DTL EIF4G1 FGFR3 FGFR2 FGFR4 STAM BCAR1 PIP4K2C SH3RF3 CIC

1.23e-0510146313int:YWHAB
InteractionFGF7 interactions

FGFR3 FGFR2 FGFR4

1.58e-0516633int:FGF7
InteractionFGF9 interactions

FGFR3 FGFR2 FGFR4

1.58e-0516633int:FGF9
InteractionCRLF2 interactions

SLC25A46 FGFR3 FGFR2 FGFR4

3.96e-0561634int:CRLF2
InteractionHSPA1B interactions

DDR1 FN1 FGFR3 FGFR2 FGFR4 CIC FAF1

4.18e-05301637int:HSPA1B
InteractionGOPC interactions

DDR1 SLC34A1 EIF4G1 FGFR3 FGFR2 FGFR4 BCAR1

4.36e-05303637int:GOPC
InteractionSEC24A interactions

SLC25A46 DDR1 SEC24A FGFR3 FGFR4 BCAR1

7.06e-05224636int:SEC24A
InteractionZNF326 interactions

DDR1 CHD3 FGFR3 FGFR2 RUNX1 CIC

7.06e-05224636int:ZNF326
InteractionCDK1 interactions

DLG5 FN1 DTL EIF4G1 FGFR3 FGFR4 PIP4K2C RUNX1 CIC

8.59e-05590639int:CDK1
InteractionSTAM2 interactions

PPP1R13B PTPN23 FGFR2 FGFR4 STAM

9.65e-05147635int:STAM2
InteractionCBFA2T3 interactions

RANBP10 SEC24A TMF1 RUNX1

1.04e-0478634int:CBFA2T3
InteractionSTAM interactions

PTPN23 FGFR2 FGFR4 STAM BCAR1

1.16e-04153635int:STAM
InteractionWDR5 interactions

ATN1 FN1 UBAP2L TPP1 DTL EIF4G1 PPP1R3F CHD3 ALDH1B1 RUNX1 CIC HNRNPR

1.34e-0411016312int:WDR5
InteractionLILRA5 interactions

EBF2 FGFR4 STAM

1.35e-0432633int:LILRA5
InteractionFGFR1 interactions

DLG5 DVL1P1 SEC24A PPP1R13B FGFR3 FGFR2 FGFR4 STAM BCAR1

1.45e-04632639int:FGFR1
InteractionNCK2 interactions

DDR1 ATN1 DVL1 FGFR4 BCAR1 NUTM2F

1.67e-04262636int:NCK2
InteractionXRN2 interactions

TPP1 EIF4G1 CHD3 ALDH1B1 RUNX1 CIC HNRNPR

1.82e-04381637int:XRN2
InteractionCLTC interactions

SLC25A46 FN1 EIF4G1 PTPN23 STAM ALDH1B1 PIP4K2C RUNX1 CIC

1.89e-04655639int:CLTC
InteractionUROD interactions

CHD3 RUNX1 FAF1

2.10e-0437633int:UROD
InteractionC1QB interactions

COL12A1 FN1 FGFR3 FGFR4

2.14e-0494634int:C1QB
InteractionWDR26 interactions

RANBP10 FGFR3 FGFR2 FGFR4 FAF1

2.42e-04179635int:WDR26
InteractionWWP2 interactions

ATN1 DAZAP1 UBAP2L ARRDC1 EIF4G1 DVL1 PPP1R13B STAM FAF1 HNRNPR

2.58e-048406310int:WWP2
InteractionUNK interactions

UBAP2L SEC24A EIF4G1 PPP1R13B STAM BCAR1 HECA

2.76e-04408637int:UNK
InteractionFBXO2 interactions

MEST NPTX2 COL12A1 FN1 FGFR3 FGFR2 FGFR4

2.88e-04411637int:FBXO2
InteractionFRS2 interactions

DDR1 FGFR3 FGFR2 FGFR4

2.93e-04102634int:FRS2
InteractionSMAP2 interactions

FN1 UBAP2L PTPN23 FGFR2 FGFR4

3.11e-04189635int:SMAP2
InteractionBCAR1 interactions

SLC34A1 SEC24A PTPN23 FGFR3 FGFR2 FGFR4 STAM BCAR1

3.25e-04556638int:BCAR1
InteractionZMYND8 interactions

ATN1 CHD3 DNAH7 CIC HNRNPR

3.27e-04191635int:ZMYND8
InteractionZFYVE9 interactions

EIF4G1 PTPN23 FGFR2 FGFR4

3.39e-04106634int:ZFYVE9
InteractionFGF4 interactions

FGFR3 FGFR2 FGFR4

3.52e-0444633int:FGF4
InteractionFGF1 interactions

FGFR3 FGFR2 FGFR4

3.52e-0444633int:FGF1
InteractionFGF17 interactions

FGFR3 FGFR2 FGFR4

3.52e-0444633int:FGF17
InteractionDDX17 interactions

FN1 CHD3 ALDH1B1 RUNX1 CIC FAF1 HNRNPR

3.58e-04426637int:DDX17
InteractionTSG101 interactions

ARRDC1 PPP1R13B PTPN23 FGFR4 STAM BCAR1

3.64e-04303636int:TSG101
InteractionFXR2 interactions

ATN1 DAZAP1 UBAP2L CECR2 EIF4G1 CHD3 HNRNPR

3.79e-04430637int:FXR2
InteractionFUBP1 interactions

FN1 DAZAP1 EIF4G1 CHD3 RUNX1 HNRNPR

4.04e-04309636int:FUBP1
GeneFamilyReceptor Tyrosine Kinases|CD molecules

DDR1 FGFR3 FGFR2 FGFR4

1.29e-0640374321
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

MYOM1 FGFR3 FGFR2 FGFR4

3.18e-04161374593
GeneFamilyFibronectin type III domain containing

COL12A1 FN1 MYOM1

4.24e-03160373555
GeneFamilyADAM metallopeptidase domain containing|CD molecules

DDR1 FGFR3 FGFR2 FGFR4

8.32e-03394374471
GeneFamilyRNA binding motif containing

DAZAP1 PPRC1 HNRNPR

9.33e-03213373725
CoexpressionVETTER_TARGETS_OF_PRKCA_AND_ETS1_UP

FN1 UBAP2L RUNX1

6.90e-0616623M14495
CoexpressionWEST_ADRENOCORTICAL_TUMOR_MARKERS_UP

NPTX2 DTL FGFR4

1.88e-0522623M205
CoexpressionMEISSNER_BRAIN_HCP_WITH_H3K4ME3_AND_H3K27ME3

EBF2 TBX18 NPTX2 COL12A1 TENM4 FN1 EIF4EBP1 DTL FGFR3 FGFR2 RUNX1

3.88e-0510746211M1941
CoexpressionGSE46606_DAY1_VS_DAY3_CD40L_IL2_IL5_STIMULATED_BCELL_UP

EBF2 MEST TENM4 MYOM1 LMO7DN

8.79e-05190625M9871
CoexpressionHU_GENOTOXIC_DAMAGE_24HR

DDR1 UBAP2L EIF4EBP1

9.25e-0537623MM1170
CoexpressionHU_GENOTOXIC_DAMAGE_24HR

DDR1 UBAP2L EIF4EBP1

9.25e-0537623M1531
CoexpressionGSE5589_LPS_VS_LPS_AND_IL6_STIM_IL10_KO_MACROPHAGE_45MIN_DN

ATN1 PPRC1 CECR2 TMF1 PCOLCE2

1.09e-04199625M6632
CoexpressionGSE27859_MACROPHAGE_VS_CD11C_INT_F480_INT_DC_DN

EBF2 UBAP2L BCAT2 ALDH1B1 OSGEP

1.09e-04199625M8587
CoexpressionGSE27786_LIN_NEG_VS_NEUTROPHIL_DN

DDR1 SLC34A1 ZNRF1 HECA CIC

1.12e-04200625M4795
CoexpressionRICKMAN_HEAD_AND_NECK_CANCER_A

NPTX2 CECR2 PCOLCE2 LGR6

1.13e-04105624M14228
ToppCellPND01-03-samps-Mesenchymal|PND01-03-samps / Age Group, Lineage, Cell class and subclass

HOXB1 FN1 EIF4EBP1 DACT3 PCOLCE2 FGFR3 FGFR4

1.25e-081946474f9bd0ded0dde1df885850714f29e73e992539a5
ToppCellPND01-03-samps-Mesenchymal-Matrix_fibroblast|PND01-03-samps / Age Group, Lineage, Cell class and subclass

HOXB1 FN1 EIF4EBP1 DACT3 PCOLCE2 FGFR3 FGFR4

1.35e-0819664754f4cf778f95a9ff662e5c7520916a25e605bf95
ToppCell15-Trachea-Mesenchymal-Mesenchyme_RSPO2+|Trachea / Age, Tissue, Lineage and Cell class

MEST ATN1 FN1 CHD3 FGFR3 FGFR2

1.91e-07174646fa0681e91724b9a51ee28b214ea5aa14e62ba1a3
ToppCellCOVID-19-Heart-VSMC|COVID-19 / Disease (COVID-19 only), tissue and cell type

EBF2 CACNA1C TBX18 DACT3 LGR6 SH3RF3

1.98e-071756461125f0d3a5b2388fa77a820dea0288e824d84a82
ToppCellFetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CACNA1C COL12A1 TENM4 FN1 RUNX1 SH3RF3

2.49e-07182646ed6ae0fd8653f213fe29906a6a4e0729a62e1b75
ToppCellCOVID-19-Heart-Fib_+_EC_+_Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

EBF2 CACNA1C TBX18 COL12A1 TENM4 FN1

2.49e-07182646fbd5e332df73bf7141c822fa67b76367dc962017
ToppCellCOVID-19-Heart-Fib_2|COVID-19 / Disease (COVID-19 only), tissue and cell type

EBF2 TBX18 COL12A1 TENM4 FN1 PCOLCE2

2.74e-071856468f95d8e591bf7379d13f5a0545b0cb49e2b1ab5d
ToppCellFetal_29-31_weeks-Mesenchymal-myofibroblast_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CACNA1C COL12A1 TENM4 FN1 RUNX1 SH3RF3

2.92e-07187646c104fbfef2d0bef64077ac721edf2379fd59d547
ToppCellPND07-28-samps-Mesenchymal-Matrix_fibroblast|PND07-28-samps / Age Group, Lineage, Cell class and subclass

HOXB1 FN1 DACT3 PCOLCE2 FGFR3 FGFR4

3.11e-07189646dc5164591dea45b420798b94dda211be03daa70c
ToppCellPND01-03-samps-Mesenchymal-Matrix_fibroblast-MatrixFB-A|PND01-03-samps / Age Group, Lineage, Cell class and subclass

HOXB1 FN1 DACT3 PCOLCE2 FGFR3 FGFR4

3.31e-07191646e7c605b56934d1383237c1f946dbccef25d91368
ToppCellCOVID-19-Heart-Fib_2|Heart / Disease (COVID-19 only), tissue and cell type

EBF2 TBX18 COL12A1 TENM4 FN1 PCOLCE2

3.62e-07194646d91c9f2ec47319051fc398320693fddbe8bbd4d6
ToppCell10x3'2.3-week_17-19-Mesenchymal_osteo-stroma-osteoblast_precursor|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

MEST COL12A1 TENM4 FN1 PCOLCE2 FGFR4

3.73e-07195646ec12cfb2fce44cc2de4e198ef5af075e626f0329
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

EBF2 MEST COL12A1 TENM4 FN1 PCOLCE2

4.08e-071986469541d68a1a6247dbd7161a62644eea6527c2c8ff
ToppCellE18.5-samps-Mesenchymal-Matrix_fibroblast-MatrixFB-A|E18.5-samps / Age Group, Lineage, Cell class and subclass

HOXB1 FN1 PCOLCE2 FGFR3 FGFR4

3.88e-06164645519ab4fe885dfe4c50846f346a062acc2cb44299
ToppCell368C-Fibroblasts-Fibroblast-B_(Myofibroblast)|368C / Donor, Lineage, Cell class and subclass (all cells)

MEST COL12A1 TENM4 PPRC1 LGR6

4.49e-061696451d5ce2c97f7ef7bdc9f861938077a9aa31d84db6
ToppCell368C-Fibroblasts-Fibroblast-B_(Myofibroblast)-|368C / Donor, Lineage, Cell class and subclass (all cells)

MEST COL12A1 TENM4 PPRC1 LGR6

4.49e-0616964558098f8801ca941aeddafb47e88ab0df8b9edb57
ToppCellP15-Mesenchymal-mesenchymal_fibroblast-mesenchymal_progenitor_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

TENM4 FN1 PCOLCE2 FGFR4 LGR6

4.62e-06170645ba4ba66b624089ed50a9083176386c7941b4c7a3
ToppCellE18.5-samps-Mesenchymal-Matrix_fibroblast|E18.5-samps / Age Group, Lineage, Cell class and subclass

HOXB1 FN1 EIF4EBP1 DACT3 FGFR4

6.44e-06182645ceb37c214662a48efb56ab0d015977c6fab478b0
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_Arw_fibro_(16)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

EBF2 CACNA1C TENM4 FGFR2 RUNX1

7.16e-061866454d68ee3d32f7ef884faf402ef92b31b0eb4656f1
ToppCellFibroblast-A|World / shred on cell class and cell subclass (v4)

FN1 DACT3 PCOLCE2 FGFR3 FGFR4

7.54e-061886456740bed5fb8f45b6eea17041894b804214c2a4ae
ToppCellE12.5-Mesenchymal-mesenchymal_fibroblast-tracheal_fibroblast|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MEST PCOLCE2 FGFR3 FGFR2 FGFR4

7.54e-061886459b95730ddd13eb4624321bab3ab4989414977ca3
ToppCellMesenchymal-myofibroblast_cell|World / Lineage, Cell type, age group and donor

CACNA1C COL12A1 TENM4 FN1 SH3RF3

7.74e-0618964544e37f88137bb249933eb615235b2cf2ae7f3925
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CECR2 LMO7DN PPP1R13B FGFR3 FGFR2

7.94e-061906458aea807a2bcf0b653b4de6202b6ecb0f0683cc2e
ToppCellPND07-28-samps-Mesenchymal-Matrix_fibroblast-FB-3|PND07-28-samps / Age Group, Lineage, Cell class and subclass

HOXB1 FN1 DACT3 PCOLCE2 FGFR3

7.94e-061906451196b8ea2c44c7c80f5ee589dd517e6a413f2077
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL12A1 FN1 DACT3 LGR6 SH3RF3

7.94e-0619064570c86dd454afb21d4a85db56c5f369d4b342bc97
ToppCellP03-Mesenchymal-mesenchymal_fibroblast-alveolar_fibroblast_Wnt2-pa|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

FN1 EIF4EBP1 PCOLCE2 FGFR3 FGFR4

8.35e-061926452802fae55683345ff94a1ecf73b6fbee4f17481e
ToppCellP03-Mesenchymal-mesenchymal_fibroblast|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

FN1 EIF4EBP1 PCOLCE2 FGFR3 FGFR4

8.35e-06192645e79f2253e084a9ab9afcaf7ec42a5012ade42d36
ToppCellPND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FN1 EIF4EBP1 PCOLCE2 FGFR3 FGFR4

8.56e-061936458d05805295c5d3aa93aeb38be5fbefa81e1be1f0
ToppCellPND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FN1 EIF4EBP1 PCOLCE2 FGFR3 FGFR4

8.56e-061936451b2cc627b2aa002b442358bd1188d470e67ce7d9
ToppCellCOVID-19-Fibroblasts-Other_FB|COVID-19 / group, cell type (main and fine annotations)

CACNA1C COL12A1 TENM4 FN1 SH3RF3

8.56e-06193645e6b75be08e33c1de079fb5c02f0b4468128b369c
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TBX18 COL12A1 FN1 MYOM1 LGR6

8.78e-06194645ebb038f94f49f5c655578d1b018676e10c6b7e3c
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

EBF2 CACNA1C MEST TENM4 FN1

8.78e-0619464585e00861c5068a27d0cf0ae677f420c8245baa9a
ToppCellPND07-Mesenchymal-Mesenchymal_structural-Fibroblastic|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FN1 EIF4EBP1 PCOLCE2 FGFR3 FGFR4

9.00e-06195645b616ee6f1d878935d293c8e0a8bbc5b4385301f0
ToppCellPND01-Mesenchymal-Mesenchymal_structural|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FN1 EIF4EBP1 PCOLCE2 FGFR3 FGFR4

9.00e-061956456bb6349d6ec8da094fe1c7c590021989337aeb0b
ToppCellCOVID-19-Heart-Fib_1|Heart / Disease (COVID-19 only), tissue and cell type

EBF2 TBX18 COL12A1 TENM4 FN1

9.00e-06195645f423baa36ac7cdc383c033e35a7d17e6bf913323
ToppCellPND01-Mesenchymal-Mesenchymal_structural-Fibroblastic|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FN1 EIF4EBP1 PCOLCE2 FGFR3 FGFR4

9.00e-06195645a3b468125e48f072255cede7645f6692298ecf54
ToppCellPND07-Mesenchymal-Mesenchymal_structural|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FN1 EIF4EBP1 PCOLCE2 FGFR3 FGFR4

9.00e-061956452f9a274b26fc528a85f50933ec2f4db1dc9da0ca
ToppCell15-Trachea-Mesenchymal|Trachea / Age, Tissue, Lineage and Cell class

MEST TBX18 COL12A1 FN1 PCOLCE2

9.23e-061966457e178c76285e61c721c38d7a995ebf89dc428f9f
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Mesenchymal-skeletal_muscle_satellite_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MEST DDR1 TENM4 FGFR4 RUNX1

9.23e-061966453dc6394c5de1f875a19ad0e8799827fad29f8f02
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FN1 EIF4EBP1 PCOLCE2 FGFR3 FGFR4

9.23e-06196645617103f4a09e009fe96c28eb5e40505a4fd6dcf4
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FN1 EIF4EBP1 PCOLCE2 FGFR3 FGFR4

9.23e-06196645db64ab27374f82553ee577aec056141170f3656f
ToppCellCOVID-19-lung-Pericytes/_Smooth_Muscle|COVID-19 / Disease (COVID-19 only), tissue and cell type

CACNA1C MEST DACT3 LGR6 SH3RF3

9.23e-06196645754a3613340932563cd8424d775e18b93c3a1aaa
ToppCellwk_08-11-Mesenchymal-Fibroblast-Adventitial_fibro|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

EBF2 MEST TBX18 COL12A1 PCOLCE2

9.23e-06196645eed9fe83ffc1f79493b70778962a671dd9f481e0
ToppCell15-Trachea-Mesenchymal-Mesenchyme_SERPINF1-high|Trachea / Age, Tissue, Lineage and Cell class

MEST TBX18 COL12A1 FN1 PCOLCE2

9.23e-0619664554aefcebf13704f51de84379e2e22ec0734b9461
ToppCellPND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FN1 EIF4EBP1 PCOLCE2 FGFR3 FGFR4

9.46e-0619764506a0d7062dadda656decaf77dcef9a10b5f2698d
ToppCellBronchial-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_pulmonary|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CACNA1C FN1 MYOM1 DACT3 SH3RF3

9.46e-06197645bf0520a94ebb1d2f94de9f526d17e0b0e8fe7052
ToppCell10x5'v1-week_12-13-Mesenchymal_osteo-stroma-early_osteoblast|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

COL12A1 TENM4 FN1 PCOLCE2 FGFR3

9.46e-061976452ca5ebb708935a90b12b8e98a22ae2d664ed002e
ToppCellPND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FN1 EIF4EBP1 PCOLCE2 FGFR3 FGFR4

9.46e-06197645d35c7a36135b5ed6a7bf2f934849678eba2a0177
ToppCell367C-Fibroblasts-Fibroblast-B_(Myofibroblast)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

NPTX2 COL12A1 FN1 CHD3 RUNX1

9.69e-06198645c55608633f66e3d434c5d81324efb07c5120d2c2
ToppCellParenchymal-NucSeq-Stromal-Myofibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CACNA1C TBX18 FN1 DACT3 SH3RF3

9.69e-06198645bd42c03e384e64f61b02618cf1a5440033bb04b2
ToppCellTracheal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_systemic_arterial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

EBF2 CACNA1C MYOM1 DACT3 SH3RF3

9.69e-061986457dd874b09c81cc512ccc1e9b65f290a5f94d736e
ToppCell367C-Fibroblasts-Fibroblast-B_(Myofibroblast)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

NPTX2 COL12A1 FN1 CHD3 RUNX1

9.69e-061986453e5459038fc6ed95f529eb4d1dc5113e16c19012
ToppCell10x5'v1-week_14-16-Mesenchymal_osteo-stroma-osteoblast_precursor|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

COL12A1 TENM4 FN1 PCOLCE2 FGFR3

9.69e-06198645bc9c9f2c87282b5ef8514773e065d2a6b5dde338
ToppCell10x3'2.3-week_17-19-Mesenchymal_fibro-stroma-arteriolar_fibroblast|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

EBF2 MEST TBX18 COL12A1 FN1

9.93e-0619964595d95e9b7bd3933188998ae94986213eb0f1e5ea
ToppCellTCGA-Bile_Duct-Primary_Tumor-Cholangiocarcinoma-Intrahepatic|TCGA-Bile_Duct / Sample_Type by Project: Shred V9

ATN1 UBAP2L STAM PIP4K2C CIC

1.02e-052006451fa8422fd820d21e285a7e7c4c6fbd8b7277d2af
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_2-AT1_Progenitor|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MEST DAZAP1 PPP1R3F FGFR3

5.66e-05145644186b8bd8ac2d5c66cc29fdc2dd6751eddce3e8b8
ToppCellE16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal-matrix_-_immature_3|E16.5-samps / Age Group, Lineage, Cell class and subclass

HOXB1 ZSWIM8 COL12A1 PCOLCE2

6.29e-05149644651494e84be03dc7b061ebdfa91756a1c507b9b4
ToppCellCOVID-19-Heart-Adipocyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

MEST NPTX2 TENM4 PCOLCE2

6.97e-0515364493958bd9c951222ba5b740d1cb83fd5d78a10e1e
ToppCellEntopeduncular-Endothelial-MURAL-M1(Rgs5Acta2)-M1_1-MURAL_Mural.Rgs5Acta2.Junb_(Mural,_IEG+)|Entopeduncular / BrainAtlas - Mouse McCarroll V32

MYOM1 EIF4G1 PIP4K2C HNRNPR

7.51e-05156644029ba0832ee9c4a2c85620e4df2260e02d86b45c
ToppCellEntopeduncular-Endothelial-MURAL-M1(Rgs5Acta2)-M1_1-MURAL_Mural.Rgs5Acta2.Junb_(Mural,_IEG+)-|Entopeduncular / BrainAtlas - Mouse McCarroll V32

MYOM1 EIF4G1 PIP4K2C HNRNPR

7.51e-051566445df19a235843829f5a1a90ca21b0964ef8b4e115
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

EBF2 TBX18 LHX4 MYOM1

8.09e-05159644cfb4a8c8aac34b1a857956d98382d487abcf5444
ToppCellAdult-Mesenchymal-chondrocyte|Adult / Lineage, Cell type, age group and donor

CACNA1C TBX18 FN1 FGFR4

8.09e-051596443f7305ee76447064b5c846c4f576360a2f7e0b7c
ToppCellBronchial-10x5prime-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CACNA1C DACT3 ALDH1B1 SH3RF3

8.09e-051596447cda111bb98f1241989e49d490bdf51a712ea589
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

EBF2 TBX18 LHX4 MYOM1

8.09e-05159644a75ab494959575143cefdaec99e7aee3f318d559
ToppCellwk_08-11-Mesenchymal-Fibroblast-Alveolar_fibro|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

NPTX2 TENM4 FN1 FGFR4

9.56e-0516664465dafed953b01a9830b54309af75c7a561e88336
ToppCellAdult-Mesenchymal-vascular_smooth_muscle_cell-D175|Adult / Lineage, Cell type, age group and donor

CACNA1C TBX18 TENM4 LGR6

9.78e-05167644c4e321bb87512ea839f324c92c0f1afea891483f
ToppCelldroplet-Pancreas-Exocrine-18m-Epithelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HEBP2 FGFR3 FGFR2 FGFR4

1.07e-041716445447b78148f7bccb727e2fc108589b2af02a5d31
ToppCell343B-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

MEST DDR1 TMEM42 CECR2

1.10e-04172644d65ffff3e341af34a043a0d802d7ba4b69de36e9
ToppCellAdult-Mesenchymal-pericyte_cell-D231|Adult / Lineage, Cell type, age group and donor

CACNA1C MEST DACT3 SH3RF3

1.10e-04172644858cee96c1c06160863b4adcd7023c0d678bd50f
ToppCelldroplet-Pancreas-Exocrine-18m-Epithelial-pancreatic_ductal_cel|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HEBP2 FGFR3 FGFR2 FGFR4

1.10e-04172644a7eee0a30d2fe20c865a07b9004c6a821a72c0c4
ToppCelldroplet-Pancreas-Exocrine-18m-Epithelial-pancreatic_ductal_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HEBP2 FGFR3 FGFR2 FGFR4

1.10e-041726440a9fe2cd28203970295a1288078c66eadac1c9ed
ToppCellAdult-Mesenchymal-airway_smooth_muscle_cell|Adult / Lineage, Cell type, age group and donor

CACNA1C MYOM1 DACT3 LGR6

1.12e-04173644a5331721bd9f9a66530dd4ffe28cb3a5a8cad8fc
ToppCellAT1-AT2_cells-Donor_06|World / lung cells shred on cell class, cell subclass, sample id

COL12A1 DVL1 PPP1R13B BCAT2

1.17e-04175644bdd85ba280648a0283c1984662a34c7b840f64dd
ToppCell10x3'2.3-week_17-19-Mesenchymal_osteo-stroma-chondrocyte|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

COL12A1 FN1 PCOLCE2 FGFR3

1.22e-04177644915b848d789051a1c3bc6f6dc86955bb752276ab
ToppCellCOVID-19-Heart-VSMC|Heart / Disease (COVID-19 only), tissue and cell type

CACNA1C DACT3 LGR6 SH3RF3

1.28e-04179644a69ad6912b5c10bb9f9d800f724c792341e9bab1
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

EBF2 TBX18 COL12A1 PCOLCE2

1.31e-04180644c2746092ef251e9d5910fe96461afdd0624a24c6
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

EBF2 TBX18 COL12A1 PCOLCE2

1.31e-0418064432c6a3886428d82fb4355d987c6d2645f333447b
ToppCellBronchial_Biopsy-Mesenchymal-Smooth_muscle|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X

EBF2 CACNA1C FN1 DACT3

1.31e-041806447085a851807e6a833965e1366946db0bbc5174e2
ToppCellControl-Fibroblasts-Airway_smooth_muscle|Control / group, cell type (main and fine annotations)

CACNA1C FN1 LGR6 SH3RF3

1.31e-04180644d0de12749ef0f51f0931c6e7b9b99966bdbc3ec1
ToppCellMatrixFB-Fibroblast-A|MatrixFB / shred on cell class and cell subclass (v4)

FN1 PCOLCE2 FGFR3 FGFR4

1.31e-04180644adc64ad6033af705dd7b9163a83e20ef5c59f6eb
ToppCellFetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CACNA1C COL12A1 TENM4 FN1

1.33e-04181644d7e04e0ca549eac6d9b1192b6578f9b54943d54f
ToppCellP28-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

FN1 EIF4EBP1 PCOLCE2 FGFR4

1.36e-0418264419c5e3a9d9b3728303b682102e276adfe93aa759
ToppCell3'-Broncho-tracheal-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-SM_activated_stress_response-SM_activated_stress_response_L.2.3.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

EBF2 TBX18 MYOM1 DACT3

1.36e-0418264497bb07478f56a937b490fba121ee603db64134a1
ToppCell3'-Broncho-tracheal-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-SM_activated_stress_response|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

EBF2 TBX18 MYOM1 DACT3

1.36e-041826441c1a687f728341c209b048b6715bcddd0ac20069
ToppCell3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

EBF2 TBX18 COL12A1 PCOLCE2

1.36e-04182644d179b5deb07c20d49eb6c58d5a65904f8921de3a
ToppCellAdult-Mesenchymal-airway_smooth_muscle_cell-D175|Adult / Lineage, Cell type, age group and donor

CACNA1C TENM4 LGR6 SH3RF3

1.36e-04182644ad4d74d8b19976e1ccc3c5ba8013199338cf6fd8
ToppCellwk_15-18-Mesenchymal-Myofibro_&_SMC-Early_airway_SMC_2|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

NPTX2 MYOM1 LGR6 ALDH1B1

1.39e-04183644a1d4f25e13f5b9e92a9ca0a804a7bed5df8fb2fe
ToppCelltumor_Lung-Fibroblasts-Pericytes|tumor_Lung / Location, Cell class and cell subclass

EBF2 CACNA1C MEST COL12A1

1.39e-04183644a03dd563af9b15cb1f5de5732a229405a9f82d84
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

COL12A1 FN1 MYOM1 LGR6

1.39e-04183644667717366cb181b8a04a347e64f0f5a4dfc6ee7f
ToppCellE18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SLC25A46 TENM4 DACT3 CIC

1.42e-04184644a6dee97ee4ef9d89e11d17339e0dadaea1210ce5
ToppCellCerebellum-Macroglia|Cerebellum / BrainAtlas - Mouse McCarroll V32

DDR1 PPP1R13B FGFR3 FGFR2

1.42e-0418464491b047a01d2cad231308279ca37fa699630f7864
ToppCellCOPD-Stromal-Pericyte|COPD / Disease state, Lineage and Cell class

EBF2 CACNA1C MEST FGFR4

1.42e-04184644a56264a22dfc2d3672b20134ab7c3c7c23da5ae1
ToppCellP28-Mesenchymal-mesenchymal_fibroblast-alveolar_fibroblast_Wnt2-pa|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

FN1 EIF4EBP1 PCOLCE2 FGFR4

1.42e-04184644924400f47e6b2cdf7b0d538df75857935cf0209b
ToppCellMesenchymal_cells-Chondrocytes|World / Lineage and Cell class

COL12A1 FN1 PCOLCE2 FGFR3

1.42e-041846441e03f9f08de5ad4d45388a95afad9f23ff0d0e28
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-Fibromyocytes|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL12A1 FN1 LGR6 ALDH1B1

1.42e-0418464454e5b63f55b8d6eccad53d389ea9c78f991e1414
ToppCell5'-GW_trimst-2-LymphNode-Mesenchymal-fibroblastic-Stromal_3_(C7+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

EBF2 MEST COL12A1 TENM4

1.42e-041846444d4d8f3f44c67d74c57e7af7b7c158f0157b2f49
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-Fibromyocytes-Fibromyocytes_L.2.3.2.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL12A1 FN1 LGR6 ALDH1B1

1.42e-041846447b5678718719020b52e7c2a7bd9797987defd7ff
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DDR1 CECR2 FGFR3 FGFR2

1.45e-04185644b5277190866d9eb5b85eceaa5ba116ea6e6f286b
ToppCellP15-Mesenchymal-mesenchymal_fibroblast|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

FN1 EIF4EBP1 PCOLCE2 FGFR4

1.45e-0418564446460e74cc613df9043f5404e7342aa13cc34873
ToppCell(00)_Basal-(4)_1wkpi|(00)_Basal / shred by cell type and Timepoint

FN1 BCAT2 FGFR3 LGR6

1.45e-04185644bf82ba905e5eee1c39a2731702071d3de10a78b8
Drugchlorate

ATN1 FN1 FGFR3 FGFR2 FGFR4 OSGEP HECA

1.42e-08103637CID000019654
Drug3-(2,6-dichloro-3,5-dimethoxyphenyl)-1-(6-(4-(4-ethylpiperazin-1-yl)-phenylamino)pyrimidin-4-yl)-1-methylurea

FGFR3 FGFR2 FGFR4

8.06e-084633ctd:C568950
DrugPalifermin

FGFR3 FGFR2 FGFR4

4.01e-076633DB00039
Drug7-methylguanosine triphosphate

EIF4EBP1 EIF4G1

7.54e-062632ctd:C017516
Drugwortmannin; Down 200; 1uM; MCF7; HT_HG-U133A_EA

ZNF8 UBAP2L SEC24A PCOLCE2 FGFR2 ALDH1B1

1.39e-05189636869_DN
DrugFlecainide acetate [54143-56-5]; Up 200; 8.4uM; PC3; HT_HG-U133A

ZSWIM8 NPTX2 FN1 FGFR2 FGFR4 RUNX1

1.65e-051956364318_UP
DrugPepstatin A [26305-03-3]; Down 200; 5.8uM; PC3; HT_HG-U133A

EBF2 RANBP10 ATN1 CHD3 FGFR2 RUNX1

1.70e-051966364206_DN
DrugIndapamide [26807-65-8]; Down 200; 10.6uM; HL60; HT_HG-U133A

DLG5 FN1 CHD3 ALDH1B1 RUNX1 CIC

1.70e-051966362361_DN
DrugHomosalate [118-56-9]; Up 200; 15.2uM; PC3; HT_HG-U133A

EBF2 ATN1 TPP1 FGFR2 RUNX1 CIC

1.80e-051986363797_UP
Diseasebone disease (implicated_via_orthology)

FGFR3 FGFR2 FGFR4

8.38e-085613DOID:0080001 (implicated_via_orthology)
DiseaseIntellectual Disability

ATN1 TPP1 PTPN23 CHD3 FGFR2 OSGEP CIC HNRNPR

3.80e-06447618C3714756
DiseaseIsolated coronal synostosis

FGFR3 FGFR2

4.20e-062612cv:CN043619
DiseaseLacrimoauriculodentodigital syndrome

FGFR3 FGFR2

1.26e-053612C0265269
DiseaseSaethre-Chotzen Syndrome

FGFR3 FGFR2

1.26e-053612C0175699
DiseaseCongenital hypoplasia of radius

FGFR3 FGFR2

1.26e-053612C0685381
DiseaseLevy-Hollister syndrome

FGFR3 FGFR2

1.26e-053612cv:C0265269
DiseaseTWIST1-related craniosynostosis

FGFR3 FGFR2

2.52e-054612cv:C4551902
DiseaseDiGeorge syndrome (is_implicated_in)

DVL1P1 DVL1

4.19e-055612DOID:11198 (is_implicated_in)
DiseaseCraniosynostosis syndrome

FGFR3 FGFR2

8.77e-057612cv:C0010278
Diseasehigh grade glioma (implicated_via_orthology)

FGFR3 FGFR2 FGFR4

1.05e-0444613DOID:3070 (implicated_via_orthology)
Diseaselung carcinoma, estrogen-receptor negative breast cancer, ovarian endometrioid carcinoma, colorectal cancer, prostate carcinoma, ovarian serous carcinoma, breast carcinoma, ovarian carcinoma, lung adenocarcinoma, squamous cell lung carcinoma

DVL1P1 DVL1 FGFR2

1.73e-0452613EFO_0000305, EFO_0000571, EFO_0000708, EFO_0001071, EFO_0001075, EFO_0001663, EFO_1000650, EFO_1001515, EFO_1001516, MONDO_0005575
Diseasecraniosynostosis (is_implicated_in)

FGFR3 FGFR2

2.74e-0412612DOID:2340 (is_implicated_in)
DiseaseProstatic Neoplasms

DDR1 TPP1 TMF1 CHD3 FGFR4 BCAR1 RUNX1

2.74e-04616617C0033578
DiseaseMalignant neoplasm of prostate

DDR1 TPP1 TMF1 CHD3 FGFR4 BCAR1 RUNX1

2.74e-04616617C0376358
Diseasefemoral neck bone geometry

FGFR4 RUNX1

3.76e-0414612EFO_0004511
DiseaseNonorganic psychosis

CACNA1C TENM4 FGFR2

4.00e-0469613C0349204
DiseaseLimb Deformities, Congenital

CACNA1C FGFR2

5.60e-0417612C0206762
DiseaseBrachycephaly

FGFR3 FGFR2

5.60e-0417612C0221356
DiseaseCleft Palate

ATN1 FGFR3 FGFR2

6.39e-0481613C0008925
DiseaseGiant Cell Glioblastoma

FN1 FGFR3 RUNX1

7.11e-0484613C0334588
Diseaseidiopathic pulmonary fibrosis (is_marker_for)

DDR1 FGFR2

1.03e-0323612DOID:0050156 (is_marker_for)
DiseasePsychotic Disorders

CACNA1C TENM4 FGFR2

1.21e-03101613C0033975
Diseaseoral squamous cell carcinoma (is_implicated_in)

FGFR3 FGFR4

1.53e-0328612DOID:0050866 (is_implicated_in)
Diseaselarge artery stroke

FN1 SLC34A1 DTL

1.67e-03113613EFO_0005524
DiseaseSquamous cell carcinoma of lung

DDR1 FGFR2

2.00e-0332612C0149782

Protein segments in the cluster

PeptideGeneStartEntry
DGGVVDSGVYAVPPP

BCAR1

401

P56945
PPGVVNIITGYGPTA

ALDH1B1

231

P30837
TGGNTYAVPALPPGA

DDR1

581

Q08345
EIFTLGGSPYPGIPV

FGFR4

681

P22455
GGSPYPGIPVEELFS

FGFR4

686

P22455
GSAVATVPPYLGPDT

ATN1

866

P54259
GVQLPPGDYSTTPGG

EIF4EBP1

26

Q13541
PGFLNGSPTGSPYGI

EBF2

496

Q9HAK2
TSYGETGVPVPPFGC

DTL

41

Q9NZJ0
PFTSYIVSTPPGGFP

DAZAP1

261

Q96EP5
PGLTGGTVSQFPPLY

CECR2

1126

Q9BXF3
VGPYIQVPSAGSFPV

PPP1R13B

346

Q96KQ4
TVPYFAEGSGGPVPT

ARRDC1

381

Q8N5I2
PSVGGQIIPPAGYFS

PHYKPL

216

Q8IUZ5
GQPYGPTFTTGDVIG

RANBP10

156

Q6VN20
HGVVSSPYVGVGPAP

PTPN23

841

Q9H3S7
IFTLGGSPYPGIPVE

FGFR2

696

P21802
GGSPGQSPPTGYSIL

HECA

266

Q9UBI9
GRPPGLETYGFPSVT

LGR6

886

Q9HBX8
TAPVTSYVEPGSGPF

HEBP2

86

Q9Y5Z4
GLPGGSSYPPASVSQ

LMO7DN

86

F2Z398
FEPISSDEGPGTYPG

KIAA1109

1401

Q2LD37
PPDSVYSGVQPGIGT

HNRNPR

151

O43390
VVGPPQPAEGAGSTY

DLG5

91

Q8TDM6
GSSVGYPDFPTSPGS

LHX4

366

Q969G2
SGFIGSEGFPGVYPP

PCOLCE2

41

Q9UKZ9
TYVTPPGTGFLPGDT

OSGEP

31

Q9NPF4
IPGTSAYAFPSLGPV

SLC34A1

41

Q06495
TLGVPFPSSAPSGYA

HOXB1

71

P14653
SFSAPYPTAGGSAGP

DACT3

186

Q96B18
GYPSTVSTVEGHGPP

CACNA1C

1831

Q13936
SVIPEYFSGPGTPLT

COL12A1

791

Q99715
GPRGVPAGTAVTPNY

GFRA4

191

Q9GZZ7
TGYRVTTTPKNGPGP

FN1

1661

P02751
ATPPGYGAAFSAAPV

CHD3

1926

Q12873
PSIFVGPTGTGKSVY

DNAH7

1971

Q8WXX0
APGFYPGASPTEFGT

EIF4G1

126

Q04637
PTTKAYTVVGGPPGG

DVL1

646

O14640
YGGETIPGPAFNPAS

FAF1

56

Q9UNN5
EIFTLGGSPYPGIPV

FGFR3

686

P22607
PTTKAYTVVGGPPGG

DVL1P1

621

P54792
PVGAYFPGGSVTPVS

BCAT2

196

O15382
GLTPVFGPYTRPSES

MEST

216

Q5EB52
PTVPLVSGTPGAYAV

PPRC1

941

Q5VV67
TGPPALVGSYGTSPE

PIP4K2C

316

Q8TBX8
AYPALGPGVTANPGT

NUTM2D

56

Q5VT03
AYPVLGPGVTVNPGT

NUTM2F

6

A1L443
AYPVLGPGVTVNPGT

NUTM2G

6

Q5VZR2
FTYSPTPVTSGIGIG

RUNX1

326

Q01196
GATGVPPSSLNYPSG

SEC24A

306

O95486
SPGIGTPFSYAVPGQ

NPTX2

261

P47972
APGGPVITAFYSGSP

CIC

1086

Q96RK0
TIPYGEPGISSPVSG

TMF1

41

P82094
GVPGLPSTFQYGPAV

UBAP2L

916

Q14157
TPYEGPTEEPFSSGG

SLC25A46

71

Q96AG3
GETFAPPRTPSYVGV

TBX18

446

O95935
PGNYVTPVSRVPAGG

SH3RF3

516

Q8TEJ3
PVPTDVSLYPSGGTG

TENM4

391

Q6N022
SSGVSGSQVYAGPPP

STAM

396

Q92783
PVPAGGGFYLVPTFS

PPP1R3F

106

Q6ZSY5
GGVYFSEGPEPPTAS

ZSWIM8

671

A7E2V4
VTGREGFPTDAPYPT

ZNF8

121

P17098
GPPGGAVSATAYPDT

TMEM42

6

Q69YG0
PSTAGGVPFGLYTPA

ZNRF1

61

Q8ND25
PTFPASSPYVTTVGG

TPP1

376

O14773
PPVHSGRTPVTGYFV

MYOM1

1061

P52179