Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	transmembrane transporter activity	MPV17 GABRP KCNG2 SCN11A ATP7A CLCN2 SLCO4C1 SLC16A5 SLC22A2 SLC22A15 SLC25A38 KCNN2 SLC17A7 SLC40A1 ABCA10 SLC7A10	1.49e-05	1180	80	16	GO:0022857
GeneOntologyMolecularFunction	transporter activity	MPV17 GABRP KCNG2 SCN11A ATP7A CLCN2 SLCO4C1 SLC16A5 SLC22A2 SLC22A15 SLC25A38 KCNN2 SLC17A7 SLC40A1 ABCA10 SLC7A10	4.38e-05	1289	80	16	GO:0005215
GeneOntologyMolecularFunction	L-amino acid transmembrane transporter activity	SLC22A2 SLC25A38 SLC17A7 SLC7A10	1.89e-04	71	80	4	GO:0015179
GeneOntologyMolecularFunction	organic cation transmembrane transporter activity	SLC22A2 SLC22A15 SLC25A38 SLC7A10	3.45e-04	83	80	4	GO:0015101
MousePheno	hunched posture	ATP7A MYCBP2 KCNN2 SLC17A7 MCM2 SLC7A10	3.25e-06	91	63	6	MP:0001505
MousePheno	abnormal CD8-positive, alpha-beta memory T cell number	CD8B CD8B2 LMBR1L NEK8 LAIR2 SIGLEC16	7.47e-06	105	63	6	MP:0012774
MousePheno	abnormal CD8-positive, alpha-beta memory T cell morphology	CD8B CD8B2 LMBR1L NEK8 LAIR2 SIGLEC16	7.47e-06	105	63	6	MP:0010837
MousePheno	abnormal memory T cell number	CD8B CD8B2 LMBR1L NEK8 LAIR2 SIGLEC16	8.69e-05	162	63	6	MP:0008048
MousePheno	abnormal memory T cell morphology	CD8B CD8B2 LMBR1L NEK8 LAIR2 SIGLEC16	8.99e-05	163	63	6	MP:0010833
Domain	MFS_dom	SLCO4C1 SLC16A5 SLC22A2 SLC22A15 SLC17A7 SLC40A1	1.40e-05	134	73	6	IPR020846
Domain	MFS	SLCO4C1 SLC16A5 SLC22A2 SLC22A15 SLC17A7	6.47e-05	108	73	5	PS50850
Domain	-	SIGLEC12 FNDC7 CD8B MYCBP2 HLA-DRB4 OBSCN LAIR2 LINGO2 PLXNA2	1.08e-03	663	73	9	2.60.40.10
Domain	Ig-like_fold	SIGLEC12 FNDC7 CD8B MYCBP2 HLA-DRB4 OBSCN LAIR2 LINGO2 PLXNA2	1.67e-03	706	73	9	IPR013783
Domain	VWC_out	FRAS1 VWCE	2.47e-03	19	73	2	SM00215
Domain	RCC1	MYCBP2 NEK8	2.74e-03	20	73	2	PF00415
Domain	RCC1_1	MYCBP2 NEK8	3.02e-03	21	73	2	PS00625
Domain	RCC1_2	MYCBP2 NEK8	3.02e-03	21	73	2	PS00626
Domain	RCC1_3	MYCBP2 NEK8	3.02e-03	21	73	2	PS50012
Domain	Reg_chr_condens	MYCBP2 NEK8	3.31e-03	22	73	2	IPR000408
Domain	-	MYCBP2 NEK8	3.31e-03	22	73	2	2.130.10.30
Domain	RCC1/BLIP-II	MYCBP2 NEK8	3.61e-03	23	73	2	IPR009091
Domain	-	UBA5 KDSR NNT PGD	4.34e-03	169	73	4	3.40.50.720
Domain	NAD(P)-bd_dom	UBA5 KDSR NNT PGD	4.71e-03	173	73	4	IPR016040
Domain	VWC	FRAS1 VWCE	5.33e-03	28	73	2	PF00093
Pathway	REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL	SIGLEC12 CD8B CD8B2 SFTPD LAIR2 SIGLEC16	2.05e-05	135	59	6	MM14781
Pubmed	Ly-C: a third locus specifying alloantigens expressed only on thymocytes and lymphocytes.	CD8B CD8B2	5.23e-06	2	80	2	5558567
Pubmed	Cloning and modeling of CD8 beta in the amphibian ambystoma Mexicanum. Evolutionary conserved structures for interactions with major histocompatibility complex (MHC) class I molecules.	CD8B CD8B2	5.23e-06	2	80	2	12034498
Pubmed	Molecular cloning of Lyt-3, a membrane glycoprotein marking a subset of mouse T lymphocytes: molecular homology to immunoglobulin and T-cell receptor variable and joining regions.	CD8B CD8B2	5.23e-06	2	80	2	3035575
Pubmed	Molecular characterization of the murine cytotoxic T-cell membrane glycoprotein Ly-3 (CD8).	CD8B CD8B2	5.23e-06	2	80	2	3498943
Pubmed	An immunological role for the CD8 beta-chain.	CD8B CD8B2	5.23e-06	2	80	2	1534146
Pubmed	Requirement for CD8 beta chain in positive selection of CD8-lineage T cells.	CD8B CD8B2	5.23e-06	2	80	2	8108731
Pubmed	Duality of the murine CD8 compartment.	CD8B CD8B2	5.23e-06	2	80	2	24594598
Pubmed	Disruption of T lymphocyte positive and negative selection in mice lacking the CD8 beta chain.	CD8B CD8B2	5.23e-06	2	80	2	7889415
Pubmed	Murine Ly-3 restriction fragment length polymorphism and transcript size differences.	CD8B CD8B2	5.23e-06	2	80	2	2576243
Pubmed	AKXD recombinant inbred strains: models for studying the molecular genetic basis of murine lymphomas.	CD8B CD8B2	5.23e-06	2	80	2	3025647
Pubmed	Copper therapy reduces intravascular hemolysis and derepresses ferroportin in mice with mosaic mutation (Atp7amo-ms): An implication for copper-mediated regulation of the Slc40a1 gene expression.	ATP7A SLC40A1	5.23e-06	2	80	2	28219768
Pubmed	Gene transfer of the Ly-3 chain gene of the mouse CD8 molecular complex: co-transfer with the Ly-2 polypeptide gene results in detectable cell surface expression of the Ly-3 antigenic determinants.	CD8B CD8B2	5.23e-06	2	80	2	2452747
Pubmed	Distinct methylation states of the CD8 beta gene in peripheral T cells and intraepithelial lymphocytes.	CD8B CD8B2	5.23e-06	2	80	2	9233619
Pubmed	Stalk region of beta-chain enhances the coreceptor function of CD8.	CD8B CD8B2	5.23e-06	2	80	2	12847256
Pubmed	The cytoplasmic domain of CD8 beta regulates Lck kinase activation and CD8 T cell development.	CD8B CD8B2	5.23e-06	2	80	2	9647223
Pubmed	The IB-peptide marker and the Ly-3 surface alloantigen: structural studies of a V kappa-region polymorphism and a T-cell marker determined by linked genes.	CD8B CD8B2	5.23e-06	2	80	2	408079
Pubmed	Transcriptional diversity at the duplicated human CD8 beta loci.	CD8B CD8B2	5.23e-06	2	80	2	8436166
Pubmed	Characterization of the mouse CD8 beta chain-encoding gene promoter region.	CD8B CD8B2	5.23e-06	2	80	2	8781121
Pubmed	Structure and expression of the Lyt-3a gene of C.AKR mice.	CD8B CD8B2	5.23e-06	2	80	2	3169881
Pubmed	Esr, a second locus in the house mouse controlling esterase-5.	CD8B CD8B2	5.23e-06	2	80	2	7103930
Pubmed	Molecular linkage of the Ly-3 and Ly-2 genes. Requirement of Ly-2 for Ly-3 surface expression.	CD8B CD8B2	1.57e-05	3	80	2	3258885
Pubmed	Ly-36: a new mouse lymphocyte alloantigen defined by a Mus musculus molossinus-specific monoclonal antibody and controlled by a gene linked to Ly-2/3 region on chromosome 6.	CD8B CD8B2	1.57e-05	3	80	2	3378837
Pubmed	CD8αα and -αβ isotypes are equally recruited to the immunological synapse through their ability to bind to MHC class I.	CD8B CD8B2	1.57e-05	3	80	2	22081144
Pubmed	Recent duplication of the two human CD8 beta-chain genes.	CD8B CD8B2	1.57e-05	3	80	2	1541829
Pubmed	Evidence for close linkage of a mouse light chain marker with the Ly-2,3 locus.	CD8B CD8B2	1.57e-05	3	80	2	100557
Pubmed	Zinc is essential for binding of p56(lck) to CD4 and CD8alpha.	CD8B CD8B2	1.57e-05	3	80	2	9830036
Pubmed	Structural and mutational analyses of a CD8alphabeta heterodimer and comparison with the CD8alphaalpha homodimer.	CD8B CD8B2	1.57e-05	3	80	2	16356863
Pubmed	Genetic correlation of a mouse light chain variable region marker with a thymocyte surface antigen.	CD8B CD8B2	1.57e-05	3	80	2	4547628
Pubmed	Linkage of a 7S RNA sequence and kappa light chain genes in the mouse.	CD8B CD8B2	1.57e-05	3	80	2	2998983
Pubmed	Molecular biology and function of CD4 and CD8.	CD8B CD8B2	1.57e-05	3	80	2	2493728
Pubmed	Interaction of the nuclear matrix-associated region (MAR)-binding proteins, SATB1 and CDP/Cux, with a MAR element (L2a) in an upstream regulatory region of the mouse CD8a gene.	CD8B CD8B2	1.57e-05	3	80	2	9218488
Pubmed	A new mouse lymphocyte alloantigen (Ly-35) controlled by the Ly-2/3 region on chromosome 6.	CD8B CD8B2	1.57e-05	3	80	2	3346044
Pubmed	Interleukin-4-induced loss of CD8 expression and cytolytic function in effector CD8 T cells persists long term in vivo.	CD8B CD8B2	1.57e-05	3	80	2	23311920
Pubmed	Unraveling a revealing paradox: Why major histocompatibility complex I-signaled thymocytes "paradoxically" appear as CD4+8lo transitional cells during positive selection of CD8+ T cells.	CD8B CD8B2	1.57e-05	3	80	2	12810689
Pubmed	A CD8 genomic fragment that directs subset-specific expression of CD8 in transgenic mice.	CD8B CD8B2	1.57e-05	3	80	2	9126989
Pubmed	CD8 binding to MHC class I molecules is influenced by T cell maturation and glycosylation.	CD8B CD8B2	1.57e-05	3	80	2	11754824
Pubmed	The synthesis and processing of beta-glucuronidase in normal and egasyn deficient mouse kidney.	CD8B CD8B2	1.57e-05	3	80	2	7236294
Pubmed	Constitutive CD8 expression drives innate CD8+ T-cell differentiation via induction of iNKT2 cells.	CD8B CD8B2	1.57e-05	3	80	2	31980555
Pubmed	An essential role for the stalk region of CD8 beta in the coreceptor function of CD8.	CD8B CD8B2	1.57e-05	3	80	2	19109142
Pubmed	Endobrevin maps to chromosome 2 in human and chromosome 6 in mouse.	CD8B CD8B2	1.57e-05	3	80	2	9878266
Pubmed	Structural basis of the CD8 alpha beta/MHC class I interaction: focused recognition orients CD8 beta to a T cell proximal position.	CD8B CD8B2	1.57e-05	3	80	2	19625641
Pubmed	The crystal structure of CD8 in complex with YTS156.7.7 Fab and interaction with other CD8 antibodies define the binding mode of CD8 alphabeta to MHC class I.	CD8B CD8B2	1.57e-05	3	80	2	18929574
Pubmed	Recombination between kappa chain genetic markers in the mouse.	CD8B CD8B2	1.57e-05	3	80	2	6437974
Pubmed	Calyculin A inhibits expression of CD8alpha but not CD4 in human peripheral blood T cells.	CD8B CD8B2	1.57e-05	3	80	2	11131152
Pubmed	Role of CD8beta domains in CD8 coreceptor function: importance for MHC I binding, signaling, and positive selection of CD8+ T cells in the thymus.	CD8B CD8B2	1.57e-05	3	80	2	10795739
Pubmed	Reduced thymic maturation but normal effector function of CD8+ T cells in CD8 beta gene-targeted mice.	CD8B CD8B2	1.57e-05	3	80	2	8064243
Pubmed	Role of CD8+ T cells and lymphoid dendritic cells in protection from ocular herpes simplex virus 1 challenge in immunized mice.	CD8B CD8B2	1.57e-05	3	80	2	24807710
Pubmed	CD8beta knockout mice mount normal anti-viral CD8+ T cell responses--but why?	CD8B CD8B2	1.57e-05	3	80	2	19088062
Pubmed	CD8alpha/alpha homodimers fail to function as co-receptor for a CD8-dependent TCR.	CD8B CD8B2	1.57e-05	3	80	2	17506031
Pubmed	Bop: a new T-cell-restricted gene located upstream of and opposite to mouse CD8b.	CD8B CD8B2	1.57e-05	3	80	2	7590968
Pubmed	Developmentally regulated glycosylation of the CD8alphabeta coreceptor stalk modulates ligand binding.	CD8B CD8B2	1.57e-05	3	80	2	11719190
Pubmed	Genetic polymorphism at the mouse immunoglobulin J kappa locus (Igk-J) as demonstrated by Southern hybridization and nucleotide sequence analysis.	CD8B CD8B2	1.57e-05	3	80	2	2875941
Pubmed	Interplay between TCR affinity and necessity of coreceptor ligation: high-affinity peptide-MHC/TCR interaction overcomes lack of CD8 engagement.	CD8B CD8B2	1.57e-05	3	80	2	14568922
Pubmed	The Bop gene adjacent to the mouse CD8b gene encodes distinct zinc-finger proteins expressed in CTLs and in muscle.	CD8B CD8B2	1.57e-05	3	80	2	9013956
Pubmed	The CD8beta ectodomain contributes to the augmented coreceptor function of CD8alphabeta heterodimers relative to CD8alphaalpha homodimers.	CD8B CD8B2	1.57e-05	3	80	2	9973530
Pubmed	Differential susceptibility of mouse Lyt-2 and Lyt-3 genes to negative regulation.	CD8B CD8B2	1.57e-05	3	80	2	8423051
Pubmed	Isolation and characterization of the mouse CD8 beta-chain (Ly-3) genes. Absence of an intervening sequence between V- and J-like gene segments.	CD8B CD8B2	1.57e-05	3	80	2	2784466
Pubmed	Isolation of P1 bacteriophage clones containing large contiguous segments of the human and mouse loci for the T-cell coreceptor molecule CD8.	CD8B CD8B2	1.57e-05	3	80	2	7710778
Pubmed	Mapping the binding site on CD8 beta for MHC class I reveals mutants with enhanced binding.	CD8B CD8B2	1.57e-05	3	80	2	16951356
Pubmed	Recombination between kappa chain genetic markers and the Lyt-3 locus.	CD8B CD8B2	1.57e-05	3	80	2	6411613
Pubmed	Functional and molecular analysis of the double-positive stage-specific CD8 enhancer E8III during thymocyte development.	CD8B CD8B2	1.57e-05	3	80	2	15661911
Pubmed	Sialic acid capping of CD8beta core 1-O-glycans controls thymocyte-major histocompatibility complex class I interaction.	CD8B CD8B2	3.13e-05	4	80	2	12459555
Pubmed	CD8α dendritic cells drive establishment of HSV-1 latency.	CD8B CD8B2	3.13e-05	4	80	2	24695322
Pubmed	The T cell receptor's alpha-chain connecting peptide motif promotes close approximation of the CD8 coreceptor allowing efficient signal initiation.	CD8B CD8B2	3.13e-05	4	80	2	18523287
Pubmed	CD8 regulates T regulatory cell production of IL-6 and maintains their suppressive phenotype in allergic lung disease.	CD8B CD8B2	3.13e-05	4	80	2	21115736
Pubmed	{gamma}{delta} T cell homeostasis is established in competition with {alpha}{beta} T cells and NK cells.	CD8B CD8B2	3.13e-05	4	80	2	16203967
Pubmed	cAMP responsive element modulator (CREM) α mediates chromatin remodeling of CD8 during the generation of CD3+ CD4- CD8- T cells.	CD8B CD8B2	3.13e-05	4	80	2	24297179
Pubmed	CD8 is needed for development of cytotoxic T cells but not helper T cells.	CD8B CD8B2	3.13e-05	4	80	2	1673361
Pubmed	Ly antigens associated with T cell recognition and effector function.	CD8B CD8B2	3.13e-05	4	80	2	6442265
Pubmed	T cell killing does not require the formation of a stable mature immunological synapse.	CD8B CD8B2	3.13e-05	4	80	2	15048111
Pubmed	CD3 delta establishes a functional link between the T cell receptor and CD8.	CD8B CD8B2	3.13e-05	4	80	2	12215456
Pubmed	Autoimmune diabetes-prone NOD mice express the Lyt2 alpha (Lyt2.1) and Lyt3 alpha (Lyt3.1) alleles of CD8.	CD8B CD8B2	3.13e-05	4	80	2	8537123
Pubmed	Generation and function of bone marrow-derived dendritic cells from CD4/CD8(-/-) double-knockout mice.	CD8B CD8B2	3.13e-05	4	80	2	10369133
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	ZNF384 MYOF CRYBG2 FRAS1 SLC16A5 MYCBP2 NEK8 RRP12 OBSCN DEPDC5 WDR90	4.48e-05	1105	80	11	35748872
Pubmed	CD8-β ADP-ribosylation affects CD8(+) T-cell function.	CD8B CD8B2	5.20e-05	5	80	2	23575529
Pubmed	The flagellin-TLR5-Nox4 axis promotes the migration of smooth muscle cells in atherosclerosis.	TLR5 NOX4	5.20e-05	5	80	2	31292433
Pubmed	Impairment of T cell development in deltaEF1 mutant mice.	CD8B CD8B2	5.20e-05	5	80	2	9126927
Pubmed	Ligand-engaged TCR is triggered by Lck not associated with CD8 coreceptor.	CD8B CD8B2	5.20e-05	5	80	2	25427562
Pubmed	Coreceptor signal strength regulates positive selection but does not determine CD4/CD8 lineage choice in a physiologic in vivo model.	CD8B CD8B2	5.20e-05	5	80	2	17082573
Pubmed	A novel Cd8-cis-regulatory element preferentially directs expression in CD44hiCD62L+ CD8+ T cells and in CD8αα+ dendritic cells.	CD8B CD8B2	5.20e-05	5	80	2	25548254
Pubmed	The organization of the immunoglobulin kappa locus in mice.	CD8B CD8B2	5.20e-05	5	80	2	3138071
Pubmed	CD8 T cell-mediated rejection of intestinal allografts is resistant to inhibition of the CD40/CD154 costimulatory pathway.	CD8B CD8B2	5.20e-05	5	80	2	11403253
Pubmed	The kinase domains of obscurin interact with intercellular adhesion proteins.	OBSCN KCNN2	5.20e-05	5	80	2	23392350
Pubmed	Acute knockdown of Depdc5 leads to synaptic defects in mTOR-related epileptogenesis.	SLC17A7 DEPDC5	5.20e-05	5	80	2	32113911
Pubmed	Chromosomal localization of the genes encoding rat CD4, CD8alpha, and CD8beta.	CD8B CD8B2	5.20e-05	5	80	2	8753864
Pubmed	Sequence and evolution of the human T-cell antigen receptor beta-chain genes.	CD8B CD8B2	7.79e-05	6	80	2	3860845
Pubmed	Negative regulation of CD8 expression via Cd8 enhancer-mediated recruitment of the zinc finger protein MAZR.	CD8B CD8B2	7.79e-05	6	80	2	16491076
Pubmed	The Ig kappa L chain allelic groups among the Ig kappa haplotypes and Ig kappa crossover populations suggest a gene order.	CD8B CD8B2	7.79e-05	6	80	2	2898504
Pubmed	An anchored molecular map of mouse chromosome 6 with an analysis of interference.	CD8B CD8B2	7.79e-05	6	80	2	8563173
Pubmed	Differential requirement for CCR4 in the maintenance but not establishment of the invariant Vγ5(+) dendritic epidermal T-cell pool.	CD8B CD8B2	7.79e-05	6	80	2	24069263
Pubmed	Dissecting the role of retinoic acid receptor isoforms in the CD8 response to infection.	CD8B CD8B2	1.09e-04	7	80	2	24610012
Pubmed	Genetic nomenclature for loci controlling mouse lymphocyte antigens.	CD8B CD8B2	1.09e-04	7	80	2	3817907
Pubmed	Paired Siglec receptors generate opposite inflammatory responses to a human-specific pathogen.	SIGLEC12 SIGLEC16	1.09e-04	7	80	2	28100677
Pubmed	Genetic linkage relationships of loci specifying differentiation alloantigens in the mouse.	CD8B CD8B2	1.09e-04	7	80	2	5021438
Pubmed	Linkage of the murine transforming growth factor alpha gene with Igk, Ly-2, and Fabp1 on chromosome 6.	CD8B CD8B2	1.09e-04	7	80	2	8100806
Pubmed	Initial characterization of STS markers in the LSXSS series of recombinant inbred strains.	CD8B CD8B2	1.45e-04	8	80	2	8012109
Pubmed	Reversible defects in natural killer and memory CD8 T cell lineages in interleukin 15-deficient mice.	CD8B CD8B2	1.45e-04	8	80	2	10704459
Pubmed	Cutting edge: blockade of the CD28/B7 costimulatory pathway inhibits intestinal allograft rejection mediated by CD4+ but not CD8+ T cells.	CD8B CD8B2	1.45e-04	8	80	2	10452966
Pubmed	Evidence that CD4+, but not CD8+ T cells are responsible for murine interleukin-2-deficient colitis.	CD8B CD8B2	1.86e-04	9	80	2	7589135
Pubmed	Rank signaling links the development of invariant γδ T cell progenitors and Aire(+) medullary epithelium.	CD8B CD8B2	1.86e-04	9	80	2	22425250
GeneFamily	Solute carriers	SLCO4C1 SLC16A5 SLC22A2 SLC22A15 SLC25A38 SLC17A7 SLC40A1 SLC7A10	1.81e-05	395	53	8	752
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	SIGLEC12 OBSCN SIGLEC16 LINGO2	1.26e-03	161	53	4	593
GeneFamily	CD molecules\|C2-set domain containing\|Sialic acid binding Ig like lectins	SIGLEC12 SIGLEC16	3.04e-03	28	53	2	745
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_2-Airway\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SFTPD HIPK1 NACA KCNN2 DNAH6	4.91e-06	139	79	5	6396434c1cb209193ccdf15581ec2adacf941d85
ToppCell	Posterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Bcl6\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	KCNG2 CLCN2 SLCO4C1 KCNN2 DNAH6	5.83e-06	144	79	5	08005be9e3367f78ef27e125d9cce5ca53f4bd2d
Disease	Hemolysis (disorder)	ATP7A SLC40A1	9.75e-05	6	76	2	C0019054
Disease	Extravascular Hemolysis	ATP7A SLC40A1	9.75e-05	6	76	2	C0312854
Disease	Intravascular hemolysis	ATP7A SLC40A1	9.75e-05	6	76	2	C0235574
Disease	peptidyl-glycine alpha-amidating monooxygenase measurement	SLCO4C1 MYCBP2	3.55e-04	11	76	2	EFO_0801871
Disease	Parkinson's disease (implicated_via_orthology)	HIPK1 KCNN2 SLC17A7 SLC40A1	7.35e-04	157	76	4	DOID:14330 (implicated_via_orthology)
Disease	kidney failure (biomarker_via_orthology)	SLCO4C1 SLC22A2	1.09e-03	19	76	2	DOID:1074 (biomarker_via_orthology)
Disease	platelet reactivity measurement, response to clopidogrel	MBNL2 LINGO2	1.60e-03	23	76	2	EFO_0004985, GO_1903493
Disease	Acute kidney injury	TLR5 LINGO2	1.89e-03	25	76	2	HP_0001919

Protein segments in the cluster

Peptide	Gene	Start	Entry
VVPSVMACGVTGSVS	COPS6	26	Q7L5N1
LITNCVSPFIGMSSI	ABCA10	941	Q8WWZ4
TIDCDVITLMGTPSG	BSDC1	96	Q9NW68
SFISEPMVCGVGVII	SLC7A10	441	Q9NS82
STGVQAGIPMPCFTT	PGD	411	P52209
PCSLGLATPTAVMVG	ATP7A	1001	Q04656
ICPFMGAVSGTLTVT	MTMR1	116	Q13613
PTIGASFMTKTVPCG	RAB31	36	Q13636
VVTSCTGVLPQLSMV	MCM2	311	P49736
GVVLTMPTSPGTVSC	ARHGEF17	1941	Q96PE2
TTVGFVVPFTIMLTC	APLNR	206	P35414
TATPMLDGTSLGICT	DEPDC5	1116	O75140
CMPTLVALSVISLGS	PCDH20	886	Q8N6Y1
LSMGKTPVSITGCGT	OR10V1	86	Q8NGI7
TPVSITGCGTQMFFF	OR10V1	91	Q8NGI7
SRVIFGPGVTMSTCD	FRAS1	2736	Q86XX4
FVSTKAEMTCSGILP	LSG1	446	Q9H089
PGTLEVVSGCTVDML	MGAT3	356	Q09327
VGPKGVLSVTRSCMT	GGNBP2	116	Q9H3C7
SGVLTQGSCTPLMVA	HIPK1	696	Q86Z02
MTICPGTVLLVFSIS	KCNN2	306	Q9H2S1
SCTMRGLPCGSVFSV	FNDC7	506	Q5VTL7
GCLTVSGPSTVMGAV	CD300H	21	A0A0K2S4Q6
SCGFMLEIVTPTSLS	FBXO33	256	Q7Z6M2
LGGSAKTVMITCVSP	KIF27	306	Q86VH2
VGGMVFSPGSVSVIS	PLXNA2	1216	O75051
FVAVTAVGLCLSTMP	KCNG2	186	Q9UJ96
TDLGLCVSTLPTTMG	OR51M1	81	Q9H341
ICLSGTGMKSVTGTP	MAP3K2	511	Q9Y2U5
VCGIDSSMILTVPGQ	NEK8	501	Q86SG6
AVVLIFMGSTIGCPA	LINGO2	16	Q7L985
FTTVPGLTGVCMVVV	NOX4	156	Q9NPH5
TCSTMTGPVHFTVGK	OBSCN	2441	Q5VST9
FGVVLGLMETVCSPF	G0S2	36	P27469
CMIVGSPELTFGKGT	CD8B2	116	A6NJW9
SPATVSRCGMVFVDP	DNAH6	1886	Q9C0G6
CMIVGSPELTFGKGT	CD8B	116	P10966
SMGTQPGCGLLVIVT	GPR148	206	Q8TDV2
FPTLTAMGCLASTVL	CRYBG2	1416	Q8N1P7
SFTIGAITACVEPMS	DNAAF9	851	Q5TEA3
LPGGSCMAALTVTLT	HLA-DRB4	6	P13762
FIPTGSVLCMTPATS	MBNL2	316	Q5VZF2
FVTMTSPCHFTLVTG	ENPP7	71	Q6UWV6
IVGMPGTGKTTTICT	DNA2	646	P51530
GTCSMFSRVGGIIAP	SLC22A15	436	Q8IZD6
SSMCDIGGIITPFLV	SLC22A2	471	O15244
ALTCGMAPVTSITEG	KDSR	276	Q06136
VPARTCIGVTTVLSM	GABRP	271	O00591
GTVISPGSHVTFMCR	LAIR2	36	Q6ISS4
MVDPSFTTGITCLGS	NNT	796	Q13423
LFTTCFFTPGSIMVG	TAAR3P	201	Q9P1P4
VGPCAITVGSLTFME	AANAT	176	Q16613
VCTPLGLARMFSVTG	LMBR1L	211	Q6UX01
FTPAMTGVVVTLSCS	SPPL2C	251	Q8IUH8
CFMATVTTSDIPGSP	SHISAL2A	161	Q6UWV7
ESTVFSGCQMGIPTI	TBATA	111	Q96M53
AVGQIMTFGSPVIGC	SLC40A1	191	Q9NP59
TLTMVSLGCGFVGPV	MPV17	51	P39210
GMTTVQCPDGVTFTF	MYCBP2	1846	O75592
SNGVGTLSGMVCPII	SLC17A7	441	Q9P2U7
TCQVTLPGAGVTMTR	SIGLEC12	341	Q96PQ1
IYPGLVGAVTMVSCS	RRP12	906	Q5JTH9
VGSRSVAGVCMSPIT	SLC25A38	131	Q96DW6
SALATTIPVPCGAFM	CLCN2	446	P51788
TIVSIFKSSPLMGCF	TMX3	366	Q96JJ7
PVIMGSFAAPVCTSS	TRAK2	891	O60296
PCGSAVPTLKSMVTF	ZNF132	26	P52740
VPVPSTGLMTAGVSC	ZNF384	91	Q8TF68
VGPSRCTVTVMGSAS	WDR90	851	Q96KV7
MVTQGLTLGFPTCIG	SLC16A5	21	O15375
TLVMCSSVESGLPGR	SFTPD	36	P35247
TFMAGTPITVSILRC	SLCO4C1	591	Q6ZQN7
REGVCAASLPTTMGV	UBA5	246	Q9GZZ9
PVGFSMTETAVGIRC	VWCE	126	Q96DN2
VVCSGEVGTASPMAR	SCART1	531	Q4G0T1
IGTVIINCVFMATGP	SCN11A	136	Q9UI33
VSTSFITPVGGAMPC	VWA3B	1076	Q502W6
VVLMAGPVFGIPSCS	TLR5	11	O60602
LSFSVHCKSGPMTGV	SIGLEC16	421	A6NMB1
TFEVATCVSPPMSSG	NACA	456	E9PAV3
MASITSPSLVVECGG	MYOF	1321	Q9NZM1