Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionguanyl-nucleotide exchange factor activity

DENND4B EGF

4.55e-0323192GO:0005085
DomainIg_2

IGSF1 FCER1A

5.33e-047392PF13895
DomainImmunoglobulin

IGSF1 FCER1A

3.54e-0319092IPR013151
Domainig

IGSF1 FCER1A

3.54e-0319092PF00047
DomainIg_sub2

IGSF1 FCER1A

5.35e-0323592IPR003598
DomainIGc2

IGSF1 FCER1A

5.35e-0323592SM00408
DomainIg_sub

IGSF1 FCER1A

1.64e-0242192IPR003599
DomainIG

IGSF1 FCER1A

1.64e-0242192SM00409
DomainIG_LIKE

IGSF1 FCER1A

2.20e-0249192PS50835
DomainIg-like_dom

IGSF1 FCER1A

2.30e-0250392IPR007110
PathwayREACTOME_INTRACELLULAR_SIGNALING_BY_SECOND_MESSENGERS

MTA3 EGF

4.55e-0325262MM15585
PathwayREACTOME_INTRACELLULAR_SIGNALING_BY_SECOND_MESSENGERS

MTA3 EGF

6.95e-0331362M27867
Pubmed

Definition of mouse chromosome 1 and 3 gene linkage groups that are conserved on human chromosome 1: evidence that a conserved linkage group spans the centromere of human chromosome 1.

FCER1A EGF

2.08e-0527922574151
InteractionBCL11B interactions

MTA3 SHPRH

3.67e-047482int:BCL11B
InteractionPWWP2A interactions

MTA3 SHPRH

3.87e-047682int:PWWP2A
InteractionCHD5 interactions

MTA3 SHPRH

3.97e-047782int:CHD5
InteractionZNF219 interactions

MTA3 SHPRH

5.43e-049082int:ZNF219
InteractionLIN37 interactions

MTA3 SHPRH

5.79e-049382int:LIN37
InteractionSHPRH interactions

MTA3 SHPRH

6.30e-049782int:SHPRH
InteractionBCL11A interactions

MTA3 SHPRH

6.96e-0410282int:BCL11A
InteractionBACC1 interactions

MTA3 SHPRH

7.24e-0410482int:BACC1
InteractionLIN9 interactions

MTA3 SHPRH

8.24e-0411182int:LIN9
InteractionHMGXB4 interactions

MTA3 SHPRH

8.54e-0411382int:HMGXB4
InteractionMTF2 interactions

MTA3 SHPRH

9.30e-0411882int:MTF2
InteractionCDK2AP1 interactions

MTA3 SHPRH

9.30e-0411882int:CDK2AP1
InteractionBRMS1L interactions

MTA3 SHPRH

1.04e-0312582int:BRMS1L
InteractionGATAD1 interactions

MTA3 SHPRH

1.14e-0313182int:GATAD1
InteractionSUDS3 interactions

MTA3 SHPRH

1.32e-0314182int:SUDS3
InteractionSIN3B interactions

MTA3 SHPRH

1.44e-0314782int:SIN3B
InteractionMBD2 interactions

MTA3 SHPRH

1.72e-0316182int:MBD2
InteractionMYBL2 interactions

MTA3 SHPRH

1.74e-0316282int:MYBL2
InteractionSAP30 interactions

MTA3 SHPRH

1.85e-0316782int:SAP30
InteractionPHF1 interactions

MTA3 SHPRH

1.96e-0317282int:PHF1
InteractionMTA3 interactions

MTA3 SHPRH

1.98e-0317382int:MTA3
InteractionSAP130 interactions

MTA3 SHPRH

2.17e-0318182int:SAP130
InteractionSMARCA1 interactions

MTA3 SHPRH

2.34e-0318882int:SMARCA1
InteractionZNF512B interactions

MTA3 SHPRH

2.54e-0319682int:ZNF512B
InteractionBPTF interactions

MTA3 SHPRH

2.56e-0319782int:BPTF
InteractionARID4B interactions

MTA3 SHPRH

2.61e-0319982int:ARID4B
InteractionHAT1 interactions

MTA3 SHPRH

3.10e-0321782int:HAT1
InteractionGATAD2A interactions

MTA3 SHPRH

3.30e-0322482int:GATAD2A
InteractionGATAD2B interactions

MTA3 SHPRH

3.93e-0324582int:GATAD2B
InteractionMTA1 interactions

MTA3 SHPRH

5.20e-0328382int:MTA1
InteractionMBD3 interactions

MTA3 SHPRH

5.64e-0329582int:MBD3
GeneFamilyImmunoglobulin like domain containing

IGSF1 FCER1A

3.04e-0319382594
ToppCellHippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-C1ql2|Hippocampus / BrainAtlas - Mouse McCarroll V32

RTL3 RASL10A IGSF1

1.32e-0611493f48fd7d378626eb7ef972ff1df87dd6149cb355c
ToppCellHippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-C1ql2-Excitatory_Neuron.Slc17a7.C1ql2-Cck_(Dentate_Principal_cells)|Hippocampus / BrainAtlas - Mouse McCarroll V32

RTL3 IGSF1

2.90e-041299208ecebb7f09d105dfdfd2191fc310910d3baec0f
ToppCellHippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1|Hippocampus / BrainAtlas - Mouse McCarroll V32

RTL3 RASL10A

3.61e-0414492e2a2f260f5ebaaef46248d199c407a15ce9d024a
ToppCellTCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Tall_Cell-1|TCGA-Thryoid / Sample_Type by Project: Shred V9

RTL3 FCER1A

4.23e-041569245a05c7a45a3ec8551818ab67f18b3b9553934c1
ToppCellPCW_10-12-Hematologic_ErythroMegGranulo-Hem_ErythroMeg-im_megakaryocyte1_(20)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

FCER1A EGF

4.23e-0415692c380142e49b1e4ecacbf37587aafa57f8562b6ad
ToppCelldroplet-Fat-SCAT-30m-Hematologic|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IGSF1 FCER1A

4.45e-0416092759749f708c3a2b36692d42499f19aff937e592f
ToppCelldroplet-Fat-SCAT-30m-Hematologic-erythroblast|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IGSF1 FCER1A

4.45e-0416092fc76337ad766c859db390ef8b6fb9caeaace3a56
ToppCelldroplet-Fat-SCAT-30m-Hematologic-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IGSF1 FCER1A

4.45e-041609267ee7a314d7d4d3ea206e0158083f36f6dd7e80b
ToppCellsevere-HSPC|severe / disease stage, cell group and cell class

RASL10A FCER1A

4.73e-0416592acd837d88ad3786c263f74651a6c0e02fa2fa2c5
ToppCell10x5'-lymph-node_spleen-Hematopoietic_progenitors-Progenitor|lymph-node_spleen / Manually curated celltypes from each tissue

RTL3 RASL10A

4.73e-04165927b992843bd8ef92a7a76b1d681fa84efde6f5bdd
ToppCellremission-HSPC|World / disease stage, cell group and cell class

RASL10A FCER1A

4.79e-0416692d269ee6f7adb55b05dcb5eaea96629ccb0b2d6e3
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RTL3 RASL10A

4.85e-0416792fe3338f99f94c0dac37e3d649dfdce82e4a56022
ToppCellsevere-HSPC|World / disease stage, cell group and cell class

RASL10A FCER1A

4.96e-0416992b0421b73bfdc92f7a2762b4b670b9eae124aa702
ToppCellCOVID-19_Convalescent-Hematopoietic_SC|COVID-19_Convalescent / Disease group, lineage and cell class

RASL10A FCER1A

5.02e-04170928a73d5334eed1cd9fdcc3ebeae0bdf9f945c228a
ToppCellPBMC-Convalescent-Hematopoietic-HSPC|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

RASL10A FCER1A

5.08e-0417192172db31a37b72fb87fe5f0f79da51866b90dd1ad
ToppCellPBMC-Convalescent-Hematopoietic-HSPC-HSPC-|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

RASL10A FCER1A

5.08e-0417192a4e13b304ef414722ffdc06560deeab41785e956
ToppCellPBMC-Convalescent-Hematopoietic-HSPC-HSPC|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

RASL10A FCER1A

5.08e-04171922031797d579ce373921affad70da6e50eec13664
ToppCellremission-HSPC|remission / disease stage, cell group and cell class

RASL10A FCER1A

5.08e-041719241b424e58470a2fc25632aea50a37c7c5ea17645
ToppCellPBMC-Convalescent-Hematopoietic-HSPC-HSPC|Convalescent / Location, Disease Group, Cell group, Cell class (2021.03.09)

RASL10A FCER1A

5.14e-0417292382cb5fea099110eb026a8bba6cf4c28763ea52f
ToppCellPBMC-Convalescent-Hematopoietic-HSPC|Convalescent / Location, Disease Group, Cell group, Cell class (2021.03.09)

RASL10A FCER1A

5.14e-0417292da78f7a71b7f05c5c484c9ed19ba37c55d35e870
ToppCellPBMC-Convalescent-Hematopoietic-HSPC-HSPC-|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

RASL10A FCER1A

5.14e-04172928fd3db757d54949bd583d5f0eadf63a32342cb9d
ToppCell5'-GW_trimst-2-SmallIntestine-Hematopoietic-Myeloid-Megakaryocyte|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FCER1A EGF

5.32e-0417592b85279b9efd72d7074c4226d50ce139a38c0e1c1
ToppCell3'-GW_trimst-1-LargeIntestine-Hematopoietic-Myeloid-Megakaryocyte|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FCER1A EGF

5.32e-0417592901f0181a30e5cc609dcada8d8a59f0468df6fa5
ToppCelldroplet-Lung-LUNG-30m-Epithelial-Club_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASL10A IGSF1

5.44e-0417792092a345cb802f183322aa5542341ba2d96d4f06a
ToppCelldroplet-Lung-LUNG-30m-Epithelial-club_cell_of_bronchiole|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASL10A IGSF1

5.44e-04177927ac99ff16df94b4e08d361e3d98a7b3af8d6ee3b
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RTL3 RASL10A

5.44e-041779230f82b04e48940bfcaf2c22677efe6d57ae3f1a7
ToppCellPBMC-Convalescent-Hematopoietic|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

FCER1A EGF

5.56e-041799235271a4396a533f6d960ce55d171a32d9d2fd1a4
ToppCelltumor_Lung-Myeloid_cells-CD207+CD1a+_LCs|tumor_Lung / Location, Cell class and cell subclass

RASL10A FCER1A

5.75e-0418292243779ba1009097f8fafa1a691e296ec3aeefc04
ToppCellCV-Moderate-7|Moderate / Virus stimulation, Condition and Cluster

SHPRH DENND4B

5.94e-0418592a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCell356C-Lymphocytic-CD4_T-cell-Proliferating_T_cell|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

RASL10A FCER1A

6.00e-0418692722da08cd978249a19855fd3ec8ddda780c99d83
ToppCell10x3'2.3-week_17-19-Hematopoietic-MK|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

FCER1A EGF

6.26e-041909264060e4b56ac9989e659c2d5d2a6b6edeba4d8d4
ToppCell10x3'2.3-week_17-19-Hematopoietic-MK-early_MK|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

FCER1A EGF

6.33e-04191923839bf57419d3ec3d4464277bb33301d2b7d701f
ToppCell10x5'v1-week_14-16-Hematopoietic-MK|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

FCER1A EGF

6.33e-04191927edc22e7e70697fb22690699efb352577162709b
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RTL3 RASL10A

6.39e-041929220ede290e01ad574afd122d72b59dbc52c595fad
ToppCell10x3'2.3-week_14-16-Hematopoietic-MK|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

FCER1A EGF

6.53e-0419492216cba1a04b1a24b080322bc950e7fa2dade5ff1
ToppCell10x5'v1-week_12-13-Hematopoietic-MK|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

FCER1A EGF

6.53e-0419492245a3eb6db9c862b73ad34a8cd2898a3688c16f6
ToppCellCOVID-19-COVID-19_Convalescent-Others-HSPC|COVID-19_Convalescent / Disease, condition lineage and cell class

RASL10A FCER1A

6.73e-0419792c1033a1a8b8b5c8569130aa9405a6e8e65ef7bd0
ToppCellLPS_IL1RA_TNF-Hematopoietic_Myeloid-Dendritic_cells-mDC|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

DENND4B FCER1A

6.93e-0420092f78968d4b4d907094b2c44dcf5ac557ae94e4484
DrugRo 31-8220

FCER1A EGF

1.55e-044892ctd:C064758
DrugNSC702818

RASL10A EGF

5.96e-049492CID000148193
Drug1n9a

RASL10A EGF

6.08e-049592CID004631604
DrugCortisporin

RTL3 EGF

2.09e-0317792CID000004454
Drugretinoic acid; Down 200; 1uM; PC3; HT_HG-U133A

DENND4B EGF

2.50e-03194921211_DN
Drug3-Acetamidocoumarin [779-30-6]; Up 200; 19.6uM; MCF7; HT_HG-U133A

RASL10A EGF

2.55e-03196924426_UP

Protein segments in the cluster

PeptideGeneStartEntry
RCHGWRNWDVYKVIY

FCER1A

131

P12319
CHRWVFGWIGCRWYG

OPN5

96

Q6U736
AGLYRCCYWKETGWS

IGSF1

101

Q8N6C5
GYIGERCQYRDLKWW

EGF

1006

P01133
ELWARCLLGHCYGLW

DENND4B

761

O75064
RLCAICWLYWKKYGG

MTA3

401

Q9BTC8
WVRWHKGRLCLYCGY

RTL3

436

Q8N8U3
GWRCGYLECSAKYNW

RASL10A

151

Q92737
CVKHWWVRLLYRPYC

SHPRH

871

Q149N8