Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionRNA polymerase II transcription regulatory region sequence-specific DNA binding

ZNF567 ZNF571 ZNF878 ZNF33B ZNF439 MUC1 ZNF607 ZNF559 ZNF546 ZNF124

3.26e-0514593010GO:0000977
GeneOntologyMolecularFunctioninward rectifier potassium channel activity

KCNJ18 KCNJ12

8.05e-0428302GO:0005242
GeneOntologyMolecularFunctionPDZ domain binding

KIRREL3 KCNJ18 KCNJ12

8.20e-04123303GO:0030165
GeneOntologyMolecularFunctionDNA-binding transcription factor activity, RNA polymerase II-specific

ZNF571 ZNF878 ZNF33B ZNF439 ZNF607 ZNF559 ZNF546 ZNF124

8.79e-041412308GO:0000981
GeneOntologyMolecularFunctionsolute:inorganic anion antiporter activity

SLC4A4 SLC4A1

1.05e-0332302GO:0005452
GeneOntologyMolecularFunctionbicarbonate transmembrane transporter activity

SLC4A4 SLC4A1

1.05e-0332302GO:0015106
GeneOntologyMolecularFunctioninorganic anion transmembrane transporter activity

ABCC4 SLC4A4 SLC4A1

2.11e-03171303GO:0015103
GeneOntologyBiologicalProcessregulation of nucleotide catabolic process

SLC4A4 PRXL2C SLC4A1

1.15e-0463313GO:0030811
GeneOntologyBiologicalProcessregulation of glycolytic process

SLC4A4 PRXL2C SLC4A1

1.15e-0463313GO:0006110
GeneOntologyBiologicalProcessregulation of purine nucleotide catabolic process

SLC4A4 PRXL2C SLC4A1

1.15e-0463313GO:0033121
GeneOntologyBiologicalProcessregulation of carbohydrate catabolic process

SLC4A4 PRXL2C SLC4A1

2.51e-0482313GO:0043470
GeneOntologyBiologicalProcessregulation of ATP metabolic process

SLC4A4 PRXL2C SLC4A1

3.41e-0491313GO:1903578
GeneOntologyBiologicalProcessglycolytic process

SLC4A4 PRXL2C SLC4A1

5.95e-04110313GO:0006096
GeneOntologyBiologicalProcessregulation of purine nucleotide metabolic process

SLC4A4 PRXL2C SLC4A1

6.27e-04112313GO:1900542
GeneOntologyBiologicalProcessregulation of nucleotide metabolic process

SLC4A4 PRXL2C SLC4A1

6.44e-04113313GO:0006140
GeneOntologyBiologicalProcessADP catabolic process

SLC4A4 PRXL2C SLC4A1

6.60e-04114313GO:0046032
GeneOntologyBiologicalProcesspurine nucleoside diphosphate catabolic process

SLC4A4 PRXL2C SLC4A1

7.12e-04117313GO:0009137
GeneOntologyBiologicalProcesspurine ribonucleoside diphosphate catabolic process

SLC4A4 PRXL2C SLC4A1

7.12e-04117313GO:0009181
GeneOntologyBiologicalProcesspyridine nucleotide catabolic process

SLC4A4 PRXL2C SLC4A1

7.48e-04119313GO:0019364
GeneOntologyBiologicalProcessADP metabolic process

SLC4A4 PRXL2C SLC4A1

7.66e-04120313GO:0046031
GeneOntologyBiologicalProcessribonucleoside diphosphate catabolic process

SLC4A4 PRXL2C SLC4A1

7.85e-04121313GO:0009191
GeneOntologyBiologicalProcesspyridine-containing compound catabolic process

SLC4A4 PRXL2C SLC4A1

8.23e-04123313GO:0072526
GeneOntologyBiologicalProcessnucleoside diphosphate catabolic process

SLC4A4 PRXL2C SLC4A1

8.43e-04124313GO:0009134
GeneOntologyBiologicalProcesspositive regulation of nucleotide catabolic process

SLC4A4 PRXL2C

8.65e-0429312GO:0030813
GeneOntologyBiologicalProcesspositive regulation of glycolytic process

SLC4A4 PRXL2C

8.65e-0429312GO:0045821
GeneOntologyBiologicalProcesspositive regulation of purine nucleotide catabolic process

SLC4A4 PRXL2C

8.65e-0429312GO:0033123
GeneOntologyBiologicalProcesspurine nucleoside diphosphate metabolic process

SLC4A4 PRXL2C SLC4A1

1.01e-03132313GO:0009135
GeneOntologyBiologicalProcesspurine ribonucleoside diphosphate metabolic process

SLC4A4 PRXL2C SLC4A1

1.01e-03132313GO:0009179
GeneOntologyBiologicalProcesspyruvate metabolic process

SLC4A4 PRXL2C SLC4A1

1.25e-03142313GO:0006090
GeneOntologyBiologicalProcessribonucleoside diphosphate metabolic process

SLC4A4 PRXL2C SLC4A1

1.27e-03143313GO:0009185
GeneOntologyBiologicalProcessnucleoside diphosphate metabolic process

SLC4A4 PRXL2C SLC4A1

1.43e-03149313GO:0009132
GeneOntologyBiologicalProcessbicarbonate transport

SLC4A4 SLC4A1

1.49e-0338312GO:0015701
GeneOntologyBiologicalProcessmonoatomic anion transmembrane transport

ABCC4 SLC4A4 SLC4A1

1.54e-03153313GO:0098656
GeneOntologyBiologicalProcesssynaptic membrane adhesion

LRRC4C TENM4

1.81e-0342312GO:0099560
GeneOntologyBiologicalProcessorganophosphate ester transport

ATP8B3 ABCC4 SLC4A1

1.82e-03162313GO:0015748
GeneOntologyBiologicalProcessregulation of generation of precursor metabolites and energy

SLC4A4 PRXL2C SLC4A1

2.05e-03169313GO:0043467
GeneOntologyBiologicalProcesspurine ribonucleotide catabolic process

SLC4A4 PRXL2C SLC4A1

2.05e-03169313GO:0009154
HumanPhenoHyperchloremic acidosis

SLC4A4 SLC4A1

1.67e-041382HP:0001995
HumanPhenoHypokalemia

KCNJ18 SLC4A4 SLC4A1

1.90e-047983HP:0002900
HumanPhenoAbnormal erythrocyte physiology

SLC4A4 SLC4A1

2.24e-041582HP:0020054
MousePhenoacidemia

SLC4A4 SLC4A1

2.91e-057172MP:0003030
MousePhenodecreased circulating bicarbonate level

SLC4A4 SLC4A1

6.23e-0510172MP:0003017
MousePhenometabolic acidosis

SLC4A4 SLC4A1

9.12e-0512172MP:0012551
MousePhenoabnormal blood pH regulation

SLC4A4 SLC4A1

1.08e-0413172MP:0003027
MousePhenoabnormal circulating bicarbonate level

SLC4A4 SLC4A1

1.45e-0415172MP:0003015
MousePhenoabnormal bicarbonate level

SLC4A4 SLC4A1

1.87e-0417172MP:0031394
MousePhenoabnormal bicarbonate homeostasis

SLC4A4 SLC4A1

2.11e-0418172MP:0031393
MousePhenoincreased urine calcium level

SLC4A4 SLC4A1

3.17e-0422172MP:0005441
MousePhenoabnormal urine pH

SLC4A4 SLC4A1

4.11e-0425172MP:0009348
MousePhenoacidosis

SLC4A4 SLC4A1

5.16e-0428172MP:0003031
MousePhenoabnormal urine calcium level

SLC4A4 SLC4A1

6.76e-0432172MP:0002985
DomainKRAB

ZNF567 ZNF571 ZNF878 ZNF33B ZNF439 ZNF607 ZNF559 ZNF546 ZNF124

4.39e-09358319PS50805
DomainKRAB

ZNF567 ZNF571 ZNF878 ZNF33B ZNF439 ZNF607 ZNF559 ZNF546 ZNF124

4.39e-09358319PF01352
DomainKRAB

ZNF567 ZNF571 ZNF878 ZNF33B ZNF439 ZNF607 ZNF559 ZNF546 ZNF124

5.72e-09369319SM00349
DomainKRAB

ZNF567 ZNF571 ZNF878 ZNF33B ZNF439 ZNF607 ZNF559 ZNF546 ZNF124

5.85e-09370319IPR001909
Domain-

ZNF567 ZNF571 ZNF878 ZNF33B ZNF439 ZNF607 ZNF559 ZNF546 ZNF124

1.03e-066793193.30.160.60
Domainzf-C2H2

ZNF567 ZNF571 ZNF878 ZNF33B ZNF439 ZNF607 ZNF559 ZNF546 ZNF124

1.23e-06693319PF00096
DomainZnf_C2H2/integrase_DNA-bd

ZNF567 ZNF571 ZNF878 ZNF33B ZNF439 ZNF607 ZNF559 ZNF546 ZNF124

1.24e-06694319IPR013087
DomainK_chnl_inward-rec_Kir2.2

KCNJ18 KCNJ12

2.67e-062312IPR003272
DomainZINC_FINGER_C2H2_2

ZNF567 ZNF571 ZNF878 ZNF33B ZNF439 ZNF607 ZNF559 ZNF546 ZNF124

3.08e-06775319PS50157
DomainZINC_FINGER_C2H2_1

ZNF567 ZNF571 ZNF878 ZNF33B ZNF439 ZNF607 ZNF559 ZNF546 ZNF124

3.15e-06777319PS00028
DomainZnf_C2H2-like

ZNF567 ZNF571 ZNF878 ZNF33B ZNF439 ZNF607 ZNF559 ZNF546 ZNF124

3.84e-06796319IPR015880
DomainZnf_C2H2

ZNF567 ZNF571 ZNF878 ZNF33B ZNF439 ZNF607 ZNF559 ZNF546 ZNF124

4.21e-06805319IPR007087
DomainZnF_C2H2

ZNF567 ZNF571 ZNF878 ZNF33B ZNF439 ZNF607 ZNF559 ZNF546 ZNF124

4.34e-06808319SM00355
DomainK_chnl_inward-rec_Kir_N

KCNJ18 KCNJ12

7.99e-063312IPR013673
DomainIRK_N

KCNJ18 KCNJ12

7.99e-063312PF08466
Domainzf-C2H2_6

ZNF567 ZNF571 ZNF878 ZNF439 ZNF607 ZNF546

1.11e-05314316PF13912
DomainBand3_cytoplasmic_dom

SLC4A4 SLC4A1

9.53e-059312IPR013769
DomainBand_3_cyto

SLC4A4 SLC4A1

9.53e-059312PF07565
Domain-

SLC4A4 SLC4A1

9.53e-0593123.40.1100.10
DomainPTrfase/Anion_transptr

SLC4A4 SLC4A1

1.19e-0410312IPR016152
DomainHCO3_cotransp

SLC4A4 SLC4A1

1.19e-0410312PF00955
DomainHCO3_transpt_euk

SLC4A4 SLC4A1

1.19e-0410312IPR003020
DomainHCO3_transpt_C

SLC4A4 SLC4A1

1.19e-0410312IPR011531
DomainK_chnl_inward-rec_Kir_cyto

KCNJ18 KCNJ12

3.15e-0416312IPR013518
DomainIRK

KCNJ18 KCNJ12

3.15e-0416312PF01007
Domain-

KCNJ18 KCNJ12

3.15e-04163122.60.40.1400
DomainK_chnl_inward-rec_Kir

KCNJ18 KCNJ12

3.15e-0416312IPR016449
DomainIg_E-set

KCNJ18 KCNJ12

1.29e-02104312IPR014756
PathwayREACTOME_BICARBONATE_TRANSPORTERS

SLC4A4 SLC4A1

1.46e-0410262M27335
PathwayREACTOME_BICARBONATE_TRANSPORTERS

SLC4A4 SLC4A1

1.46e-0410262MM15073
PathwayREACTOME_PHASE_4_RESTING_MEMBRANE_POTENTIAL

KCNJ18 KCNJ12

5.49e-0419262MM15194
Pubmed

Acetylation-Mimic Mutation of TRIM28-Lys304 to Gln Attenuates the Interaction with KRAB-Zinc-Finger Proteins and Affects Gene Expression in Leukemic K562 Cells.

ZNF567 ZNF878 ZNF33B ZNF607 ZNF124

5.50e-0718131537372979
Pubmed

Role of Kir2.2 in hypercapnic ventilatory response during postnatal development of mouse.

KCNJ18 KCNJ12

7.69e-07231215705530
Pubmed

A substrate access tunnel in the cytosolic domain is not an essential feature of the solute carrier 4 (SLC4) family of bicarbonate transporters.

SLC4A4 SLC4A1

7.69e-07231224121512
Pubmed

Molecular cloning and functional expression of cDNA encoding a second class of inward rectifier potassium channels in the mouse brain.

KCNJ18 KCNJ12

2.31e-0633128083233
Pubmed

The consequences of disrupting cardiac inwardly rectifying K(+) current (I(K1)) as revealed by the targeted deletion of the murine Kir2.1 and Kir2.2 genes.

KCNJ18 KCNJ12

2.31e-06331211410627
Pubmed

Low-affinity spermine block mediating outward currents through Kir2.1 and Kir2.2 inward rectifier potassium channels.

KCNJ18 KCNJ12

2.31e-06331217640933
Pubmed

Targeted disruption of Kir2.1 and Kir2.2 genes reveals the essential role of the inwardly rectifying K(+) current in K(+)-mediated vasodilation.

KCNJ18 KCNJ12

2.31e-06331210904001
Pubmed

Assignment of the murine inward rectifier potassium channel Irk2 (Kir2.2) gene to the central region of mouse chromosome 11.

KCNJ18 KCNJ12

4.61e-0643128921409
Pubmed

Functional characterization of inward rectifier potassium ion channel in murine fetal ventricular cardiomyocytes.

KCNJ18 KCNJ12

4.61e-06431220798526
Pubmed

A Soluble Epoxide Hydrolase Inhibitor Upregulated KCNJ12 and KCNIP2 by Downregulating MicroRNA-29 in a Mouse Model of Myocardial Infarction.

KCNJ18 KCNJ12

4.61e-06431232990585
Pubmed

Dendritic excitability of mouse frontal cortex pyramidal neurons is shaped by the interaction among HCN, Kir2, and Kleak channels.

KCNJ18 KCNJ12

7.68e-06531216177047
Pubmed

Genetic mapping refines DFNB3 to 17p11.2, suggests multiple alleles of DFNB3, and supports homology to the mouse model shaker-2.

KCNJ18 KCNJ12

1.15e-0563129529344
Pubmed

The inward rectifier potassium channel family.

KCNJ18 KCNJ12

1.15e-0563127580148
Pubmed

Gamma motor neurons survive and exacerbate alpha motor neuron degeneration in ALS.

KCNJ18 KCNJ12

2.15e-05831227930290
Pubmed

A multiprotein trafficking complex composed of SAP97, CASK, Veli, and Mint1 is associated with inward rectifier Kir2 potassium channels.

KCNJ18 KCNJ12

3.44e-051031214960569
Pubmed

A physical map of the mouse shaker-2 region contains many of the genes commonly deleted in Smith-Magenis syndrome (del17p11.2p11.2).

KCNJ18 KCNJ12

5.96e-051331210049592
Pubmed

The transcription factor hepatocyte nuclear factor-6 controls the development of pancreatic ducts in the mouse.

SLC4A4 MUC1

1.04e-041731216472605
Pubmed

PITX2 insufficiency leads to atrial electrical and structural remodeling linked to arrhythmogenesis.

KCNJ18 KCNJ12

1.17e-041831221511879
Pubmed

Penetrance of craniofacial anomalies in mouse models of Smith-Magenis syndrome is modified by genomic sequence surrounding Rai1: not all null alleles are alike.

KCNJ18 KCNJ12

2.66e-042731217273973
Pubmed

Tbx3 controls the sinoatrial node gene program and imposes pacemaker function on the atria.

KCNJ18 KCNJ12

3.52e-043131217473172
Pubmed

Identification of new ciliary signaling pathways in the brain and insights into neurological disorders.

KIRREL3 TENM4 SLC4A4 SLC4A1

4.44e-0440531438187761
Pubmed

Axon guidance genes control hepatic artery development.

RGMA MUC1

4.75e-043631237497580
Cytoband19p13.2

ZNF878 ZNF439 ZNF559

4.97e-0422931319p13.2
Cytoband19q13.12

ZNF567 ZNF571

1.10e-037231219q13.12
CytobandEnsembl 112 genes in cytogenetic band chr19p13

ATP8B3 ZNF878 ZNF439 ZNF559

1.95e-03797314chr19p13
CytobandEnsembl 112 genes in cytogenetic band chr4q13

HTN1 SLC4A4

5.06e-03157312chr4q13
CytobandEnsembl 112 genes in cytogenetic band chr19q13

ZNF567 ZNF571 ZNF607 ZNF546

8.14e-031192314chr19q13
CytobandEnsembl 112 genes in cytogenetic band chr17p11

KCNJ18 KCNJ12

8.32e-03203312chr17p11
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF567 ZNF571 ZNF878 ZNF33B ZNF439 ZNF607 ZNF559 ZNF546 ZNF124

1.16e-0771823928
GeneFamilyPotassium voltage-gated channel subfamily J

KCNJ18 KCNJ12

1.84e-0416232276
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

KIRREL3 LRRC4C

1.76e-02161232593
ToppCellLPS_only-Epithelial_alveolar-AT_2-AT2_Progenitor|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ABCC4 TENM4 SLC4A4 MUC1

7.32e-061813140513b9e6673ff7bf8e72ba123ca3794b65d10170
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ABCC4 TENM4 SLC4A4 MUC1

7.48e-0618231417ed11a7ea366dd3106400511d5e628d3f1a9c3e
ToppCellLPS_only-Epithelial_alveolar-AT_2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ABCC4 TENM4 SLC4A4 MUC1

7.65e-06183314e972432dd4d1bd31bb0982f4df3061e5e152658f
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2-AT2_Progenitor|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ABCC4 TENM4 SLC4A4 MUC1

7.81e-06184314d0c212a8fbaad24597a84018442b25c61c17ea58
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ABCC4 TENM4 SLC4A4 MUC1

7.98e-06185314fefaf227d89f680d6f3e91c4a94e26ab4d0dc6c3
ToppCellBasal_cells-Donor_05|World / lung cells shred on cell class, cell subclass, sample id

RGMA TMPRSS12 SLC4A4

1.68e-0415531330accc72a6a914ae0c4d52b373ea1c9a98efbf22
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Fibroblasts|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TMPRSS12 SLC4A4 ZNF546

1.74e-04157313f086753b51860e23f1275bd75e8802d2a7d7b70a
ToppCellClub-club-13|World / Class top

ABCC4 SLC4A4 MUC1

1.91e-041623137d18f05a65ac715e62d610df9cc4a26539340dee
ToppCellClub-club-12|World / Class top

ABCC4 MUC1 SLC4A1

2.02e-041653139b7a31cbdcd2f96b8bd08a4cd4141b92bd5e9062
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)-Goblet_(subsegmental)_L.0.4.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TMPRSS12 SLC4A4 MUC1

2.09e-0416731331633899aae852873a4887e72c621474b0a51a33
ToppCellmild_COVID-19_(asymptomatic)-RBC|World / disease group, cell group and cell class (v2)

SLC4A4 ZNF439 SLC4A1

2.17e-041693132bda6ab3f32e05cb7daf91eb7c39b4fcc9ae91bb
ToppCellmild_COVID-19_(asymptomatic)-RBC|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)

SLC4A4 ZNF439 SLC4A1

2.24e-0417131378491478ba65bad45238fe114f5251b2adea323d
ToppCellCOVID-19-Heart-T_cell|COVID-19 / Disease (COVID-19 only), tissue and cell type

KIRREL3 LRRC4C SLC4A1

2.24e-04171313b2e753e811a7639956994609f73efcdb62d04f82
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RGMA C9orf43 SLC4A4

2.36e-041743133f0a5ce074675d57d479fa069385a1b3071e884e
ToppCell(03)_Secretory|World / shred by cell type and Timepoint

ABCC4 SLC4A4 MUC1

2.44e-04176313cb7b1945788196ca79007f0768b6576ec885a0e5
ToppCelldroplet-Lung-nan-3m-Mesenchymal-pericyte_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RGMA LRRC4C KCNJ12

2.48e-0417731365709bd546cb1ec6aa2ddd8b2adb46e174eb9a9a
ToppCelldroplet-Lung-nan-3m-Mesenchymal-Pericyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RGMA LRRC4C KCNJ12

2.48e-041773138684d47a547e2a06496f15e8da0200ecddc431e0
ToppCellLPS_only-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ABCC4 TENM4 SLC4A4

2.56e-04179313fd2cbee532e7b44113410dca82aec7db1a7fb69f
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ABCC4 SLC4A4 MUC1

2.61e-04180313b798a3fa2dd15b68aa4267f665559527043dcc07
ToppCellControl-Epithelial_cells-AT2|Control / group, cell type (main and fine annotations)

ABCC4 SLC4A4 MUC1

2.61e-04180313198b19e7910b4a8cc7e820c525ab357c7f99f578
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Hematopoietic-Megakaryocytic-Megakaryocyte|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

LCA5 LRRC4C SLC4A1

2.65e-04181313c5843b89f3d362e236ff76c3279518a2fdfc1f75
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Hematopoietic-Megakaryocytic|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

LCA5 LRRC4C SLC4A1

2.65e-0418131314c2dd946e89ba578711c2d25935b6b3d319b701
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Hematopoietic-Megakaryocytic-Megakaryocyte-Mega|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

LCA5 LRRC4C SLC4A1

2.65e-04181313fcefb5902416c004631f4f8dd5c8f99fe3bd90bc
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Hematopoietic|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

LCA5 LRRC4C SLC4A1

2.65e-041813139dc0563453e24c9d1d975e2e0e1e272487e19908
ToppCelldroplet-Lung-LUNG-1m-Mesenchymal-pericyte_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRRC4C TENM4 KCNJ12

2.69e-041823139edaccf1154cec92ca9a28e9b1f9075cfd422bfd
ToppCelldroplet-Lung-LUNG-1m-Mesenchymal-Pericyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRRC4C TENM4 KCNJ12

2.69e-04182313aba4c06d5d7618ac21b2695bca8e7a1346a91090
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRRC4C TENM4 SLC4A4

2.78e-04184313ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRRC4C TENM4 SLC4A4

2.78e-041843132cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRRC4C TENM4 SLC4A4

2.78e-041843132b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ABCC4 TENM4 SLC4A4

2.78e-04184313ab2f06906fc7a9931dfa0864ef506832b07fb93e
ToppCellCOVID-19-Heart-Fib_2|COVID-19 / Disease (COVID-19 only), tissue and cell type

RGMA KIRREL3 TENM4

2.82e-041853138f95d8e591bf7379d13f5a0545b0cb49e2b1ab5d
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_2-AT2_Progenitor|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ABCC4 SLC4A4 MUC1

2.82e-04185313929b68b05b7686341329ac756d7df172cb4b810b
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ABCC4 TENM4 SLC4A4

2.87e-04186313e83718fabb057100835d3357df407f283d23fe16
ToppCell15-Trachea-Epithelial-Secretory_progenitor|Trachea / Age, Tissue, Lineage and Cell class

LRRC4C SLC4A4 MUC1

2.92e-04187313be9fce9e74b2f170a2067f1b31d802912a578329
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KIRREL3 SLC4A4 MUC1

2.92e-0418731371d99a1a95d3692a2891da49d4a243bae6e07fd0
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ABCC4 TENM4 SLC4A4

2.96e-041883134bdf8d49af0e9da349b16e3f012e1b0eec04cc4f
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC4 LRRC4C CDKAL1

3.01e-04189313904b8337e2cabac2f0bf5dad5598fc429581ed81
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC4 MUC1 SLC4A1

3.05e-04190313bb3b396d78887d5d6f93a05c8ed4d703591bf33f
ToppCell3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.4|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KIRREL3 SLC4A4 MUC1

3.10e-04191313e96184aee03175fd9f1da11fa2b89d95ba58b817
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ABCC4 LRRC4C SLC4A4

3.10e-0419131334cc997e4e5c727495f321e6807a84aa124da486
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ABCC4 LRRC4C SLC4A4

3.15e-04192313fb2f0e897228f808d9ff734ad05e9b49dc38fa50
ToppCellwk_20-22-Epithelial-Distal_epithelial_progenitor|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

ABCC4 SLC4A4 MUC1

3.15e-04192313fa2420d6117d4800f60ef6a24bcf8bf54593cd1f
ToppCellwk_20-22-Epithelial-Distal_epithelial_progenitor-epi-tip_late|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

ABCC4 SLC4A4 MUC1

3.15e-0419231387b60014202633a4f6d19b09a5dd9276c2edecfb
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC4 MUC1 SLC4A1

3.15e-041923134842a55650fc4687c9184d498a8c05c259d15186
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ABCC4 SLC4A4 MUC1

3.20e-04193313f3cc7cfdbc164a4ed42f87647111522b7d393bcb
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT2-AT2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ABCC4 SLC4A4 MUC1

3.20e-04193313fd4d3c0d7caf8a2fff5b3d901fc28d19a8163cdf
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Colon_Adenocarcinoma-10|TCGA-Colorectal / Sample_Type by Project: Shred V9

LRRC4C TENM4 MAP3K3

3.20e-04193313194e7fa00a50cc4e026987b715323d125d79594e
ToppCellCOVID-19-Heart-Fib_2|Heart / Disease (COVID-19 only), tissue and cell type

RGMA KIRREL3 TENM4

3.25e-04194313d91c9f2ec47319051fc398320693fddbe8bbd4d6
ToppCellSkin-Tubules|Skin / Skin and Kidney Cells in Lupus Nephritis Patients.

SLC4A4 MUC1 SLC4A1

3.34e-0419631312e21cc310a261407b46e034108e8c93ea16e045
ToppCell(05)_Secretory|World / shred by cell type by condition

ABCC4 SLC4A4 MUC1

3.34e-041963138032c25b51ef96aeba28cc52686a2bd45213453d
ToppCellwk_08-11-Epithelial-Airway_epithelial_progenitor-epi-airway_progenitor_early|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

RGMA MUC1 NBEAL2

3.40e-041973134ae08ccb6f1da626c4f0fb0140a2811cb6e31ba1
ToppCell5'-Adult-Distal_Rectal-Epithelial-mature_enterocytic-Colonocyte|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC4A4 MUC1 NBEAL2

3.40e-0419731382e83b4e4f54f9aa3a4a7bbf48b6dd603adeb69b
ToppCell5'-Adult-Distal_Rectal-Epithelial-mature_enterocytic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC4A4 MUC1 NBEAL2

3.40e-041973138f894a4f0d34289f19d227788466b9fb4be15d54
ToppCellAT2_cells-IPF_04|World / lung cells shred on cell class, cell subclass, sample id

ABCC4 SLC4A4 MUC1

3.40e-04197313fd7bdfa6bf5966ebc11fdd13915769429540ddbf
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW19-Macroglial-Astrocyte|GW19 / Sample Type, Dataset, Time_group, and Cell type.

ABCC4 SLC4A4 PRXL2C

3.45e-04198313bfad1c51cf884ff7ce89f8278820800582541dc7
ToppCellLPS_IL1RA-Epithelial_alveolar-AT_2|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

ABCC4 SLC4A4 MUC1

3.45e-04198313c4e7512f0e1d115f2be8acae6048eda8b6b640b2
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_basal-Suprabasal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ABCC4 TENM4 SLC4A4

3.45e-0419831319d8ff3a4f911b13ecc34844202925475ad4d2ab
ToppCellParenchymal-10x3prime_v2-Epithelial-Epi_airway_secretory-Secretory_Goblet|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

ZNF878 TENM4 MUC1

3.45e-041983135dd2aa7684c36beffa204ca4c04d0501cabac10f
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW19-Macroglial|GW19 / Sample Type, Dataset, Time_group, and Cell type.

ABCC4 SLC4A4 PRXL2C

3.45e-041983136372e65242236c497d9b3be147092897c1609d22
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW19-Macroglial-Astrocyte|GW19 / Sample Type, Dataset, Time_group, and Cell type.

RGMA SLC4A4 PRXL2C

3.55e-042003137c66953ff6d8f16f4decd23c85232990d2d8c6c4
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW19-Macroglial|GW19 / Sample Type, Dataset, Time_group, and Cell type.

RGMA KIRREL3 SLC4A4

3.55e-042003133a954d9d542e52c9b181f0850a09b1bff0a0c82d
DiseaseRenal Tubular Acidosis, Type II

SLC4A4 SLC4A1

9.99e-072302C0268435
DiseaseRenal tubular acidosis

SLC4A4 SLC4A1

5.99e-064302C0001126
Diseaserenal tubular acidosis (is_implicated_in)

SLC4A4 SLC4A1

5.99e-064302DOID:14219 (is_implicated_in)
DiseaseDistal Renal Tubular Acidosis

SLC4A4 SLC4A1

9.97e-065302C1704380
Diseaserenal tubular acidosis (implicated_via_orthology)

SLC4A4 SLC4A1

2.79e-058302DOID:14219 (implicated_via_orthology)
Diseaseanemia (implicated_via_orthology)

SLC4A4 SLC4A1

1.04e-0415302DOID:2355 (implicated_via_orthology)
Diseasefasting blood glucose change measurement

TENM4 CDKAL1

4.86e-0432302EFO_0010120
Diseasehealth study participation

LRRC4C TUFM KCNJ12

1.01e-03195303EFO_0010130
Diseasecholangiocarcinoma (is_marker_for)

SLC4A4 MUC1

1.94e-0364302DOID:4947 (is_marker_for)
Diseasebehavioural disinhibition measurement

KIRREL3 CDKAL1

2.65e-0375302EFO_0006946
Diseasebipolar disorder

ATP8B3 TWF2 TENM4 CDKAL1

2.65e-03577304MONDO_0004985
DiseaseEsophageal Neoplasms

TUFM MAP3K3

2.86e-0378302C0014859
DiseaseMalignant neoplasm of esophagus

TUFM MAP3K3

2.86e-0378302C0546837
Diseasecalcium measurement

KIRREL3 ABCC4 MUC1 SLC4A1

3.59e-03628304EFO_0004838

Protein segments in the cluster

PeptideGeneStartEntry
YHTTSHPGTHKVYVE

SLC4A1

46

P02730
EFKDHHYYLSGVHGS

ATP8B3

406

O60423
DYSHFHKTYEVPSTP

KCNJ12

341

Q14500
DTYHPMSEYPTYHTH

MUC1

1201

P15941
AGKHHYSYLSDFETP

LCA5

16

Q86VQ0
EHEHLNHYNSYKSPF

LRRC4C

591

Q9HCJ2
HYAHTDCPGHADYVK

TUFM

121

P49411
VYFKRNYPHIGHTDH

ABCC4

1291

O15439
SRVFHSYSPYDHKIG

CDKAL1

421

Q5VV42
HKHPVTTVHDRLYGY

C9orf43

331

Q8TAL5
GYYSVNTFKEHHSTP

KIRREL3

636

Q8IZU9
KHHSHREFPFYGDYG

HTN1

36

P15515
KGGTYPRRYHVSVHH

MAP3K3

271

Q99759
PRRYHVSVHHKDYSD

MAP3K3

276

Q99759
DYSHFHKTYEVPSTP

KCNJ18

341

B7U540
DPAGTIDKFHYGTHY

NBEAL2

2146

Q6ZNJ1
HYEKSFHKHSATPNY

RGMA

146

Q96B86
YHHIEPFCKLTGYSH

PRXL2C

101

Q7RTV5
YLIDHHRTHTGEKPY

ZNF567

491

Q8N184
HYRTHTGEKPYECHE

ZNF33B

571

Q06732
GRDHEYTDHPSKGSY

RBMXL3

286

Q8N7X1
QLTVHHRFHYGEKPY

ZNF607

211

Q96SK3
HLTQHYRIHTGEKPY

ZNF546

511

Q86UE3
FRHSHSPAHKYYLAT

TENM4

1271

Q6N022
SHLYSDHYSPSGRHR

TMPRSS12

16

Q86WS5
LHYHERTHTGEKPYV

ZNF124

221

Q15973
HHTIYIGVHVPKSYR

SLC4A4

26

Q9Y6R1
RPYTHKEYVETFSHS

ZNF559

211

Q9BR84
HLTYHQRVHTGEKPY

ZNF571

321

Q7Z3V5
YHFFLYKHTHEGDPL

TWF2

236

Q6IBS0
SFHYHERTHTGEKPY

ZNF878

381

C9JN71
SFRYHERTHTGEKPY

ZNF439

396

Q8NDP4