Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionribosome binding

NOMO3 NOMO2 NOMO1

4.48e-05120123GO:0043022
GeneOntologyMolecularFunctionribonucleoprotein complex binding

NOMO3 NOMO2 NOMO1

2.22e-04206123GO:0043021
GeneOntologyMolecularFunctioncarbohydrate binding

NOMO3 NOMO2 NOMO1

7.35e-04310123GO:0030246
GeneOntologyMolecularFunctionSH3 domain binding

CD3E ADAM10

3.21e-03143122GO:0017124
GeneOntologyBiologicalProcessmulti-pass transmembrane protein insertion into ER membrane

NOMO3 NOMO2 NOMO1

1.26e-089123GO:0160063
GeneOntologyBiologicalProcessprotein insertion into ER membrane

NOMO3 NOMO2 NOMO1

6.70e-0731123GO:0045048
GeneOntologyBiologicalProcessprotein insertion into membrane

NOMO3 NOMO2 NOMO1

2.90e-0650123GO:0051205
GeneOntologyBiologicalProcessnegative regulation of nodal signaling pathway

NOMO3 NOMO1

6.51e-067122GO:1900108
GeneOntologyBiologicalProcessregulation of nodal signaling pathway

NOMO3 NOMO1

1.11e-059122GO:1900107
GeneOntologyBiologicalProcessdetermination of left/right asymmetry in lateral mesoderm

NOMO3 NOMO1

1.39e-0510122GO:0003140
GeneOntologyBiologicalProcessendoplasmic reticulum organization

NOMO3 NOMO2 NOMO1

2.89e-05107123GO:0007029
GeneOntologyBiologicalProcesslateral mesoderm development

NOMO3 NOMO1

5.86e-0520122GO:0048368
GeneOntologyBiologicalProcessnegative regulation of activin receptor signaling pathway

NOMO3 NOMO1

6.48e-0521122GO:0032926
GeneOntologyBiologicalProcessnodal signaling pathway

NOMO3 NOMO1

1.00e-0426122GO:0038092
GeneOntologyBiologicalProcessregulation of activin receptor signaling pathway

NOMO3 NOMO1

1.52e-0432122GO:0032925
GeneOntologyBiologicalProcessendomembrane system organization

NOMO3 NOMO2 DCST2 NOMO1

4.49e-04672124GO:0010256
GeneOntologyBiologicalProcesspositive regulation of CD4-positive, alpha-beta T cell activation

CD3E IL4R

5.04e-0458122GO:2000516
GeneOntologyBiologicalProcessprotein localization to membrane

NOMO3 ADAM10 NOMO2 NOMO1

5.38e-04705124GO:0072657
GeneOntologyBiologicalProcessactivin receptor signaling pathway

NOMO3 NOMO1

5.39e-0460122GO:0032924
GeneOntologyBiologicalProcessestablishment of protein localization to membrane

NOMO3 NOMO2 NOMO1

7.27e-04319123GO:0090150
GeneOntologyBiologicalProcesslocalization within membrane

NOMO3 ADAM10 NOMO2 NOMO1

8.58e-04798124GO:0051668
GeneOntologyBiologicalProcesspositive regulation of alpha-beta T cell activation

CD3E IL4R

1.18e-0389122GO:0046635
GeneOntologyBiologicalProcessmembrane organization

NOMO3 NOMO2 DCST2 NOMO1

1.42e-03914124GO:0061024
GeneOntologyBiologicalProcessregulation of CD4-positive, alpha-beta T cell activation

CD3E IL4R

1.49e-03100122GO:2000514
GeneOntologyCellularComponentmulti-pass translocon complex

NOMO3 NOMO2 NOMO1

1.21e-089123GO:0160064
GeneOntologyCellularComponentER membrane insertion complex

NOMO3 NOMO2 NOMO1

5.24e-0814123GO:0072379
DomainDUF2012

NOMO3 NOMO2 NOMO1

8.10e-104123PF09430
DomainDUF2012

NOMO3 NOMO2 NOMO1

8.10e-104123IPR019008
DomainCarb-bd-like_fold

NOMO3 NOMO2 NOMO1

1.13e-088123IPR013784
DomainCarboxyPept_regulatory_dom

NOMO3 NOMO2 NOMO1

5.77e-0813123IPR014766
Domain-

NOMO3 NOMO2 NOMO1

5.77e-08131232.60.40.1120
DomainCarboxyPept-like_regulatory

NOMO3 NOMO2 NOMO1

1.37e-0717123IPR008969
Domain-

NOMO3 CD3E TSPOAP1 NOMO2 NOMO1 IL4R

1.51e-066631262.60.40.10
DomainIg-like_fold

NOMO3 CD3E TSPOAP1 NOMO2 NOMO1 IL4R

2.17e-06706126IPR013783
DomainFN3

TSPOAP1 IL4R

6.03e-03185122SM00060
DomainFN3

TSPOAP1 IL4R

6.95e-03199122PS50853
DomainFN3_dom

TSPOAP1 IL4R

7.64e-03209122IPR003961
Domain-

SSH3 TLX1

1.37e-022831221.10.10.60
DomainHomeodomain-like

SSH3 TLX1

1.85e-02332122IPR009057
PathwayWP_TH17_CELL_DIFFERENTIATION_PATHWAY

CD3E IL4R

6.49e-046982M45541
PathwayKEGG_HEMATOPOIETIC_CELL_LINEAGE

CD3E IL4R

1.03e-038782M6856
Pubmed

Recurrent NOMO1 Gene Deletion Is a Potential Clinical Marker in Early-Onset Colorectal Cancer and Is Involved in the Regulation of Cell Migration.

NOMO3 NOMO2 NOMO1

3.14e-11312336011023
Pubmed

Silencing of nodal modulator 1 inhibits the differentiation of P19 cells into cardiomyocytes.

NOMO3 NOMO2 NOMO1

3.14e-11312325576386
Pubmed

Establishment of a conditional Nomo1 mouse model by CRISPR/Cas9 technology.

NOMO3 NOMO2 NOMO1

1.25e-10412331833031
Pubmed

A locus for autosomal recessive pseudoxanthoma elasticum, with penetrance of vascular symptoms in carriers, maps to chromosome 16p13.1.

NOMO3 NOMO2 NOMO1

1.25e-1041239267806
Pubmed

Nicalin and its binding partner Nomo are novel Nodal signaling antagonists.

NOMO3 NOMO2 NOMO1

1.76e-09812315257293
Pubmed

Substrate-driven assembly of a translocon for multipass membrane proteins.

NOMO3 NOMO2 NOMO1

2.63e-09912336261522
Pubmed

An ER translocon for multi-pass membrane protein biogenesis.

NOMO3 NOMO2 NOMO1

5.17e-091112332820719
Pubmed

Genome duplications and other features in 12 Mb of DNA sequence from human chromosome 16p and 16q.

NOMO3 NOMO2 NOMO1 IL4R

2.23e-089212410493829
Pubmed

Hepatic lipase maturation: a partial proteome of interacting factors.

NOMO3 NOMO2 NOMO1

1.40e-073112319136429
Pubmed

An FBXW7-ZEB2 axis links EMT and tumour microenvironment to promote colorectal cancer stem cells and chemoresistance.

NOMO3 NOMO2 NOMO1

1.70e-073312330783098
Pubmed

Distinct TCR signaling pathways drive proliferation and cytokine production in T cells.

CD3E ADAM10

1.09e-06512223377202
Pubmed

Transmembrane insertases and N-glycosylation critically determine synthesis, trafficking, and activity of the nonselective cation channel TRPC6.

NOMO3 NOMO2 NOMO1

1.23e-066312331266804
Pubmed

The sequence and analysis of duplication-rich human chromosome 16.

NOMO3 NOMO2 NOMO1

3.62e-069012315616553
Pubmed

Decreased Anxiety-Related Behaviour but Apparently Unperturbed NUMB Function in Ligand of NUMB Protein-X (LNX) 1/2 Double Knockout Mice.

NOMO3 NOMO2 NOMO1

6.63e-0611012327889896
Pubmed

Deterministic and stochastic allele specific gene expression in single mouse blastomeres.

NOMO3 NOMO2 DNMT3A NOMO1

9.98e-0642412421731673
Pubmed

WDFY4 is required for cross-presentation in response to viral and tumor antigens.

NOMO3 NOMO2 NOMO1

1.89e-0515612330409884
Pubmed

Transcriptome analysis in blastocyst hatching by cDNA microarray.

DNMT3A IL4R

3.26e-052512215919778
Pubmed

Proteomic identification of common SCF ubiquitin ligase FBXO6-interacting glycoproteins in three kinds of cells.

NOMO3 ADAM10 NOMO2 NOMO1

4.23e-0561312422268729
Pubmed

The addition of 5'-coding information to a 3'-directed cDNA library improves analysis of gene expression.

NOMO3 NOMO1

7.22e-05371228076819
Pubmed

LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow.

NOMO3 NOMO2 NOMO1

1.98e-0434412330333137
Pubmed

A protein interaction framework for human mRNA degradation.

NOMO3 NOMO2 NOMO1

2.03e-0434712315231747
Pubmed

Yeast two-hybrid identification of prostatic proteins interacting with human sex hormone-binding globulin.

NOMO3 NOMO1

2.04e-046212215862967
Pubmed

The SARS-coronavirus-host interactome: identification of cyclophilins as target for pan-coronavirus inhibitors.

NOMO3 NOMO1

2.38e-046712222046132
InteractionTRPC6 interactions

NOMO3 NOMO2 NOMO1

1.39e-0582123int:TRPC6
InteractionTMPRSS13 interactions

NOMO3 ADAM10 NOMO1

3.01e-05106123int:TMPRSS13
InteractionTMEM25 interactions

NOMO3 FIGNL1 NOMO1

6.05e-05134123int:TMEM25
InteractionNCLN interactions

NOMO3 NOMO2 NOMO1

1.53e-04183123int:NCLN
InteractionBRICD5 interactions

NOMO3 ADAM10 NOMO1

1.81e-04194123int:BRICD5
InteractionST14 interactions

NOMO3 ADAM10 NOMO1

2.19e-04207123int:ST14
InteractionRNF149 interactions

NOMO3 CD3E NOMO2 NOMO1

2.27e-04549124int:RNF149
InteractionBRAF interactions

NOMO3 NOMO2 NOMO1

2.35e-04212123int:BRAF
InteractionSFTPC interactions

NOMO3 ADAM10 NOMO1

2.70e-04222123int:SFTPC
InteractionEXOSC10 interactions

NOMO3 NOMO2 NOMO1

2.73e-04223123int:EXOSC10
InteractionRAPGEF4 interactions

ADAM10 TSPOAP1

3.92e-0450122int:RAPGEF4
InteractionTRGV3 interactions

ADAM10 NOMO1

4.74e-0455122int:TRGV3
InteractionFBXO6 interactions

NOMO3 ADAM10 NOMO2 NOMO1

6.26e-04717124int:FBXO6
InteractionTPCN2 interactions

NOMO3 NOMO1

6.62e-0465122int:TPCN2
InteractionNOMO3 interactions

NOMO3 NOMO1

7.03e-0467122int:NOMO3
InteractionSHBG interactions

NOMO3 NOMO1

7.46e-0469122int:SHBG
InteractionEFNA2 interactions

ADAM10 NOMO1

7.89e-0471122int:EFNA2
InteractionRNF130 interactions

NOMO3 NOMO2 NOMO1

8.21e-04325123int:RNF130
CytobandEnsembl 112 genes in cytogenetic band chr16p12

NOMO2 IL4R

8.99e-04172122chr16p12
CytobandEnsembl 112 genes in cytogenetic band chr16p13

NOMO3 NOMO1

5.33e-03426122chr16p13
GeneFamilyADAM metallopeptidase domain containing|CD molecules

CD3E ADAM10 IL4R

5.30e-0439483471
CoexpressionHUANG_GATA2_TARGETS_DN

NOMO3 NOMO2 NOMO1

1.09e-0598123MM942
CoexpressionDESCARTES_ORGANOGENESIS_MEGAKARYOCYTES

NOMO3 NOMO2 NOMO1

4.63e-05159123MM3657
CoexpressionNAKAYA_PBMC_FLUARIX_FLUVIRIN_AGE_18_50YO_CORRELATED_WITH_HAI_28DY_RESPONSE_AT_7DY_POSITIVE

NOMO3 NOMO2 NOMO1

4.89e-05162123M41204
CoexpressionMARTORIATI_MDM4_TARGETS_NEUROEPITHELIUM_UP

NOMO3 NOMO2 NOMO1

7.26e-05185123MM1115
CoexpressionGSE3039_B2_VS_B1_BCELL_DN

TSPOAP1 NOMO1 IL4R

9.15e-05200123M6453
CoexpressionZENG_GU_ICB_CONTROL_METAGENE_21_PRECICTIVE_ICB_RESISTANCE

NOMO3 NOMO2 NOMO1

9.99e-05206123MM17087
CoexpressionWANG_TUMOR_INVASIVENESS_DN

NOMO3 NOMO2 NOMO1

1.17e-04217123MM778
CoexpressionACEVEDO_LIVER_CANCER_WITH_H3K27ME3_DN

NOMO3 NOMO2 NOMO1

1.25e-04222123M16955
CoexpressionEBAUER_TARGETS_OF_PAX3_FOXO1_FUSION_DN

ADAM10 IL4R

2.23e-0449122M7778
CoexpressionHALMOS_CEBPA_TARGETS_UP

TLX1 IL4R

2.23e-0449122M11064
CoexpressionPASQUALUCCI_LYMPHOMA_BY_GC_STAGE_UP

NOMO3 NOMO2 NOMO1

2.94e-04297123MM1003
CoexpressionDAVICIONI_PAX_FOXO1_SIGNATURE_IN_ARMS_UP

ADAM10 IL4R

3.35e-0460122M4991
CoexpressionHE_LIM_SUN_FETAL_LUNG_C3_OMD_POS_ENDOTHELIAL_CELL

NOMO3 NOMO2 NOMO1

4.95e-04355123M45758
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c04-ANXA2|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CD3E NOMO2 IL4R

1.12e-0516912301a24a8817628125bd004b2be68ffa62c7111f6e
ToppCelldroplet-Lung-LUNG-1m-Lymphocytic-Proliferating_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD3E TSPOAP1 FIGNL1

1.42e-05183123769a022fe8568ec49e66f792cc5777e713a7571c
ToppCelldroplet-Lung-LUNG-1m-Lymphocytic-T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD3E TSPOAP1 FIGNL1

1.42e-05183123aac0695fafa59cabd920ee18b1139d3e00d898e8
ToppCelldroplet-Lung-1m-Hematologic-lymphocytic-Proliferating_T_cell-proliferating_T|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CD3E TSPOAP1 FIGNL1

1.46e-0518512389b85ce8026dc80c1bd9f76dfe16401c173b7946
ToppCelldroplet-Lung-1m-Hematologic-lymphocytic-Proliferating_T_cell|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CD3E TSPOAP1 FIGNL1

1.46e-051851230e0f043ad6d2a62cd47ce39911ad81feab4a4d7e
ToppCellCOPD-Endothelial-VE_Arterial|Endothelial / Disease state, Lineage and Cell class

NOMO3 NOMO2 NOMO1

1.61e-05191123ef16ad1c1cd2c0c0377957398c98775b62a81754
ToppCellControl-Endothelial-VE_Arterial|Endothelial / Disease state, Lineage and Cell class

NOMO3 NOMO2 NOMO1

1.64e-051921237e89b9125e8b85f6be85eeccef5c8644647ab0e1
ToppCellIPF-Endothelial-VE_Arterial|Endothelial / Disease state, Lineage and Cell class

NOMO3 NOMO2 NOMO1

1.64e-05192123e911e286da26202853f9650ba3cdefe5a5c9b585
ToppCellCOVID_vent-Lymphocytic-Plasma_cell-IgA_Plasmablast|COVID_vent / Disease condition, Lineage, Cell class and subclass

NOMO3 NOMO2 NOMO1

1.77e-0519712399fe44ef42c65d24fe64947fd5bf6d91b9a4b2c3
ToppCellLPS-antiTNF-Lymphocytic_NKT-T_cells-Erythroid|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CD3E FIGNL1

5.04e-0412612254247ce9ee0a4f123f1fb225600a4ec698510a86
ToppCellVE-CD8-exh_CD4|VE / Condition, Cell_class and T cell subcluster

CD3E DCST2

5.70e-041341224413fec495907184b6d5cf4bda39359506b2c172
ToppCellMild/Remission-B_intermediate-14|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

SSH3 DCST2

5.70e-041341225bd1e3fa6278facd9e949e9e5e244e700190126b
ToppCell3'_v3-Lung-Lymphocytic_T_CD8-Trm_gut_CD8|Lung / Manually curated celltypes from each tissue

CD3E DCST2

6.31e-041411227cbe8abdd004430d58ce31e0b613894a4cf6726e
ToppCellMild/Remission-B_intermediate-14|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)

SSH3 DCST2

6.31e-0414112269e32125a0e8f0c8561e5e7a93607f368f09546f
ToppCellControl-Plasmablast|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

NOMO2 NOMO1

6.67e-04145122fe68582f5a15b9714cb84fa32ac880e13cb69895
ToppCellInfluenza_Severe-CD4+_T_naive|World / Disease group and Cell class

CD3E DCST2

7.04e-04149122ce6552063510aa3e0b9d6e5b531eea67410e7056
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c01-FCGR3A|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

NOMO3 NOMO1

7.42e-041531224eb9c2d7e4b95d44198fc87dc115a08ef0153e26
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_ILC-NK_cell|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

NOMO3 NOMO1

7.42e-0415312226b5b45c117d155b028d298a0b93e16d343dca97
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_ILC|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

NOMO3 NOMO1

7.42e-041531220f12e38f2cbf69a520764289b0aa4dedc645f714
ToppCell367C-Lymphocytic-CD4_T-cell-Treg_cell_3|367C / Donor, Lineage, Cell class and subclass (all cells)

CD3E DCST2

7.42e-04153122da1bff9928d8c61bb1c389d45fd897cfa4bed023
ToppCell10x5'-bone_marrow-Lymphocytic_T_CD8-Trm_gut_CD8|bone_marrow / Manually curated celltypes from each tissue

SSH3 CD3E

7.51e-0415412293145a1bc5712ae664690b03a9e00ce1f92cfc7e
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c10-MKI67-GZMK|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

NOMO3 CD3E

7.61e-041551225687416773809b8c478567bc54310af102b3029a
ToppCellsaliva-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CD3E NOMO1

7.71e-041561228790b4b400695571fcf1ccb24c658b5e90854ff7
ToppCellInfluenza_Severe-CD4+_T_naive|Influenza_Severe / Disease group and Cell class

CD3E DCST2

7.80e-04157122287bdc4e455cd0160261a93d13538e0def49fcd4
ToppCell367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0|367C / Donor, Lineage, Cell class and subclass (all cells)

CD3E TSPOAP1

7.90e-04158122c08b5e12cc2975e52965e22ec987d0d45a9a68e9
ToppCellHealthy/Control-CD8+_T_naive|World / Disease group and Cell class

CD3E DNMT3A

7.90e-0415812270680b29428b6bf882b1fae36f924b775961176b
ToppCelldroplet-Lung-nan-3m-Lymphocytic-Proliferating_NK|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPOAP1 FIGNL1

7.90e-04158122ee8ce3cd202807df692b28bb1a81827d49d73862
ToppCellBac-SEP-Lymphocyte-T_NK-MAIT|Bac-SEP / Disease, Lineage and Cell Type

CD3E DCST2

8.00e-04159122e043c65f3febdfa7f75a67702e92fcdebe144a00
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-CD8_NK_sig-Z|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CD3E ADAM10

8.00e-04159122bf8ff9251bcb64b2b9d6dd93461aec97659686ec
ToppCellICU-NoSEP-Lymphocyte-T_NK-Treg|ICU-NoSEP / Disease, Lineage and Cell Type

CD3E NOMO2

8.00e-04159122d065ec02a4f3672ba53d4fea66029f1ce68f367f
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c03-GZMK|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

CD3E FIGNL1

8.10e-041601228e2b51d7b42e0b6e62641efdbbc73d31561d6a3e
ToppCellInfluenza_Severe-gd_T|World / Disease group and Cell class

CD3E DCST2

8.20e-04161122b3cdaed4d58d57e3c5dbc904a09388f3bf949407
ToppCell5'-Adult-SmallIntestine-Hematopoietic-T_cells-TRGV4_gdT|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CD3E TSPOAP1

8.41e-0416312211cc18f36604d9a5f4e7fb8626a8f0fb141da5e1
ToppCellfacs-Liver-Liver_non-hepato/SCs_st-18m-Lymphocytic-T_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD3E FIGNL1

8.51e-041641221a9b444d2c6abcc83d4355ec5228b27541df2bd0
ToppCell5'-Adult-LymphNode-Hematopoietic-T_cells-TRGV5/7_gdT|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CD3E TSPOAP1

8.61e-04165122207f9ca8839f54710e2112986def4bc7b0ef1a28
ToppCelldroplet-Liver-LIVER-NPC-1m-Lymphocytic-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SSH3 CD3E

8.61e-041651228c7a6f9e2ca0ce077426d3d0726e3f5a4c03b296
ToppCell3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_T/NK-CD8-positive,_alpha-beta_T_cell-CD8_T_cells-CD8_T_cells_L.1.1.0.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CD3E TSPOAP1

8.72e-0416612226f3d5e5e30b63b09b89cda23c423d12d887631f
ToppCell3'-Child09-12-SmallIntestine-Hematopoietic-T_cells-TRGV2_gdT|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CD3E TSPOAP1

8.72e-0416612262523e635784512b3261b672beaa7747cb9d114a
ToppCell3'-Child04-06-SmallIntestine-Hematopoietic-T_cells-Th1|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CD3E DCST2

8.82e-041671229c55ec8f70b86d4d3d5c2a6ecd9bff2dafe68c11
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c03-GZMK|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

CD3E NOMO2

8.82e-04167122abc4ba308ca3be41b0da604f5d82579fd58dff7b
ToppCellPND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CD3E FIGNL1

8.82e-0416712253e32d6687a07f486141df9f4ab998af4c03a507
ToppCelltumor_Lymph_Node_/_Brain-T/NK_cells-CD8+/CD4+_Mixed_Th|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

CD3E TSPOAP1

8.82e-04167122c0c944eae0514dc8e00d0c2892a0792e157695ec
ToppCellPND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD8_T-CD8_T_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CD3E FIGNL1

8.93e-04168122ade02beb8d663fce4be2aefa10392ab849a4bbe7
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

CD3E NOMO2

8.93e-04168122b94b1f37c92e019d01ecfa3b7cc6797b6e4a56ff
ToppCelldroplet-Lung-nan-3m-Lymphocytic-Proliferating_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD3E FIGNL1

9.03e-04169122f6a6d2f614d60395ad9b867ff1cf59eba72b04ce
ToppCelldroplet-Lung-nan-3m-Lymphocytic-T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD3E FIGNL1

9.03e-04169122df2c9c706bfc9db2bc5726602a49f5f5a94e9481
ToppCelldroplet-Lung-nan-18m-Lymphocytic-Regulatory_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD3E TSPOAP1

9.14e-04170122064786c1f1ad7665358964765910b0ad46d14685
ToppCelldroplet-Lung-nan-18m-Lymphocytic-regulatory_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD3E TSPOAP1

9.14e-041701226725747df336697708b94999b3ebb40f1721da16
ToppCellfacs-Heart-RV-24m-Lymphocytic-T_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD3E TSPOAP1

9.24e-04171122eee1199332c09aaae021134ee7c91661b11df50a
ToppCelldroplet-Lung-18m-Hematologic-lymphocytic-regulatory_T_cell-regulatory_T_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CD3E TSPOAP1

9.24e-041711227c0a1b0676f6749ee710c6bdeca6d6f7fac79b69
ToppCellfacs|World / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAM10 DNMT3A

9.24e-04171122c9990bc041a632b2f7bbebbfe737772c423d7027
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-CD4_rest-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CD3E TSPOAP1

9.24e-04171122e1fe07652c10c37191d1471ddaea500f74269e0c
ToppCellfacs-Heart-RV-24m-Lymphocytic-T_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD3E TSPOAP1

9.24e-04171122dbffd55db0b3fc6eeb38d05189d84653f0111b31
ToppCelldroplet-Lung-18m-Hematologic-lymphocytic-regulatory_T_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CD3E TSPOAP1

9.24e-0417112210492832db8ebc3cf85503c441f33bd94df9458e
ToppCellnormal_Pleural_Fluid-T/NK_cells-Cytotoxic_CD8+_T|normal_Pleural_Fluid / Location, Cell class and cell subclass

CD3E NOMO2

9.24e-041711226be81c20f4e962b414afcedfe478dd59c510d1e1
ToppCelldroplet-Lung-3m-Hematologic-lymphocytic-CD4-positive,_alpha-beta_T_cell-CD4-positive,_alpha-beta_T_cell_l21|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CD3E TSPOAP1

9.35e-041721221aecc98a3eadabae0f1f328091a9733d916017ec
ToppCellPND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CD3E FIGNL1

9.35e-041721224bdcf1ae2a1cfba0272c54072e37fb7958904321
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-Treg-Treg_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CD3E FIGNL1

9.35e-04172122282017db72d0537ac82aecc69393ccde9590be60
ToppCelldroplet-Marrow-nan-24m-Hematologic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD3E FIGNL1

9.46e-0417312237825d0dda028cf677ff6ff16ea58bff75cb25a7
ToppCelldroplet-Marrow-nan-24m-Hematologic-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD3E FIGNL1

9.46e-0417312235dc897e06f905419d44093a92170d2cec35dd51
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c08-IL2RB|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

CD3E TSPOAP1

9.68e-0417512263e977b8bafae1c5f742fc35a4cc712fefa9727f
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

CD3E FIGNL1

9.79e-041761226b1cf1e98b4509e87f9eea827fa7090ce1e504f1
ToppCelldroplet-Lung-3m-Hematologic-myeloid-myeloid_dendritic_cell-proliferating_dendritic|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TSPOAP1 FIGNL1

9.79e-04176122581045e61cdcdfa85701343d1a7c0a72a36606a7
ToppCellCV-Severe-7|CV / Virus stimulation, Condition and Cluster

ADAM10 NOMO2

9.79e-041761223de0c7d77210049e5616db21eed1490a17a5ec2d
ToppCell3'-Pediatric_IBD-SmallIntestine-Hematopoietic-T_cells-NK_T_cell|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CD3E TSPOAP1

9.79e-04176122dbc4f64cd39b229f2355ca1d0215cc7f6a767dce
ToppCelldroplet-Lung-21m-Hematologic-lymphocytic-regulatory_T_cell-regulatory_T_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CD3E TSPOAP1

9.90e-04177122fd4a297e519b3959811a462d63feebff76429031
ToppCelldroplet-Lung-21m-Hematologic-lymphocytic-regulatory_T_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CD3E TSPOAP1

9.90e-04177122e995230ef207dcd87eab4550617589016ffa9970
ToppCelldroplet-Lung-18m-Hematologic-lymphocytic-CD4-positive,_alpha-beta_T_cell-CD4-positive,_alpha-beta_T_cell_l9|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CD3E FIGNL1

9.90e-0417712244c38e572a9e9678c2dbb3e8b4748e7e28d404b7
ToppCelldroplet-Lung-nan-18m-Lymphocytic-Proliferating_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD3E FIGNL1

1.00e-0317812279823d13652177de852c2acce9159049241f1d86
ToppCell3'-GW_trimst-2-SmallIntestine-Hematopoietic-T_cells-ILC2|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CD3E IL4R

1.00e-031781225101a45595cd8d702f911afadf1eb0ee10bdcefc
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c02-GPR183|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

CD3E DNMT3A

1.00e-0317812231c847d7f7aa0f6d820afbb45d507992f5e9dc2f
ToppCelldroplet-Lung-3m-Hematologic-lymphocytic-Proliferating_T_cell-proliferating_T|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CD3E FIGNL1

1.03e-0318112274311aac2fe27dc02a9be3bc20e0c7ef1c239049
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c03-GZMK|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

NOMO3 CD3E

1.03e-0318112212ff56fa2949c8d53360cdf2cacfd326e65b54aa
ToppCelldroplet-Lung-3m-Hematologic-lymphocytic-Proliferating_T_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CD3E FIGNL1

1.03e-03181122cf13bf7a531a2d40f8d778629cf2431b684f65f3
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Stem-like-OPC-like-OPC-like-B|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NOMO2 FIGNL1

1.05e-03182122a9948a30c6297bd236588148937f294985221986
ToppCelldroplet-Thymus-nan-3m-Lymphocytic-Double_negative_Thymocyte,_DN4_(Cd8-,_Cd4-),_some_undergoing_VDJ_recombination_|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD3E DNMT3A

1.06e-03183122a0a3e4d07ac73dbbb1e019fd11e88ccffe6cf2ca
ToppCelldroplet-Lung-18m-Hematologic-lymphocytic-Proliferating_T_cell-proliferating_T|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CD3E FIGNL1

1.07e-031841221edefa2a049d7e22d0bdb1ea3d7ef1c8d6ae0fe3
ToppCelldroplet-Lung-18m-Hematologic-lymphocytic-Proliferating_T_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CD3E FIGNL1

1.07e-031841228578c50eaa8ce1cefc0228185c66c8e25f4bfc32
ToppCellfacs-Thymus-nan-3m-Lymphocytic-DN4_thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD3E DNMT3A

1.08e-03185122d50406a9a5b8d75110ba5985741aa2293950c543
ToppCellCV-Moderate-7|Moderate / Virus stimulation, Condition and Cluster

ADAM10 NOMO2

1.08e-03185122a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCellfacs-Thymus-nan-3m-Lymphocytic-DN4_thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD3E DNMT3A

1.08e-03185122a2cae8c657e4f4d121476798e424876f7e247973
ToppCelldroplet-Thymus-nan-3m-Lymphocytic-double_negative_T_cell|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD3E DNMT3A

1.09e-0318612211929e36d8c9b4c4bc2f5e912f139f474f91ab00
ToppCelldroplet-Lung-LUNG-30m-Lymphocytic-T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD3E FIGNL1

1.09e-0318612261de94c9ba90e7b6780694199c059c798b1488ae
ToppCellmetastatic_Lymph_Node-Fibroblasts-COL14A1+_matrix_FBs|Fibroblasts / Location, Cell class and cell subclass

TSPOAP1 FIGNL1

1.09e-031861226259f0f2d5bc863782d09a901d6be2f387d1f074
ToppCellCV-Moderate-7|CV / Virus stimulation, Condition and Cluster

ADAM10 NOMO2

1.09e-031861228571956890fc9894d766ba294a28e376b4aba428
ToppCell10x5'v1-week_12-13-Hematopoietic-HSC/MPP_and_pro-CMP|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

TSPOAP1 DNMT3A

1.09e-03186122895905f1d1a01ffd5617a0baa8818693a7e9cb3b
ToppCelldroplet-Marrow-nan-24m-Lymphocytic-naive_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPOAP1 NOMO1

1.10e-0318712281d7c3802667190f11e9dcd797ee7b88aadbb8de
ToppCelldroplet-Fat-Gat-18m-Lymphocytic-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD3E TSPOAP1

1.10e-03187122f2665d115fd74448b8c7627e963e061992424121
ToppCelldroplet-Fat-Gat-18m-Lymphocytic|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD3E TSPOAP1

1.10e-03187122c65c049dfb3be771547f694d725f8b1dfc4938ab
ToppCell(1)_T_CD4_naive|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)

CD3E DNMT3A

1.12e-03188122b8f67ac2faadd5b848955e43ab5d6cf5e49b3681
ToppCelldroplet-Lung-nan-21m-Lymphocytic-Proliferating_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD3E FIGNL1

1.12e-0318812261ae7405ab56570409bf35382dc0a038e4137c15
ToppCelldroplet-Mammary_Gland|droplet / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD3E IL4R

1.13e-03189122d159892c9c4eb78d747ae6b44267a88cf870d31a
ToppCell3'-Pediatric_IBD-SmallIntestine-Hematopoietic-T_cells-gdT|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CD3E TSPOAP1

1.14e-03190122116314a27064d3005d950c9a9163b79ea438707b
ToppCelldroplet-Lung-30m-Hematologic-lymphocytic-Proliferating_T_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CD3E FIGNL1

1.14e-0319012208420f0ecd2c62e102371d16dcb8eda0d510e92a
ToppCelldroplet-Lung-30m-Hematologic-lymphocytic-Proliferating_T_cell-proliferating_T|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CD3E FIGNL1

1.14e-03190122f5a8b44d9948a16e2d5284c78d8f7ed422ac623a
ToppCellPBMC-Convalescent-Lymphocyte-T/NK-CD4+_T-CD4+_T_naive|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CD3E DNMT3A

1.15e-03191122ffcb2c8dbcf40281b439f4b719b5b341972ffb9a
ToppCell10x5'-lymph-node_spleen-Lymphocytic_T_CD4/8-lo-Tgd_CRTAM|lymph-node_spleen / Manually curated celltypes from each tissue

CD3E TSPOAP1

1.15e-03191122f802a4686ecf00e8302047bfe23356f24b266cf8
ToppCelldroplet-Lung-LUNG-30m-Lymphocytic-Proliferating_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD3E FIGNL1

1.15e-03191122239300ff76f2c855b2b04d3002461158be90a01b
DrugNSC145391

CD3E TLX1 IL4R

7.02e-05159123CID000286683
DrugCefmetazole sodium salt [56796-39-5]; Down 200; 8.2uM; PC3; HT_HG-U133A

SSH3 ADAM10 IL4R

1.31e-041961235868_DN
DrugFlumethasone [2135-17-3]; Down 200; 9.8uM; HL60; HT_HG-U133A

SSH3 ADAM10 IL4R

1.31e-041961232551_DN
DrugAceclofenac [89796-99-6]; Down 200; 11.2uM; PC3; HT_HG-U133A

SSH3 ADAM10 IL4R

1.31e-041961237269_DN
DrugSulfinpyrazone [57-96-5]; Down 200; 9.8uM; MCF7; HT_HG-U133A

ADAM10 DNMT3A IL4R

1.31e-041961233192_DN
DrugDiprophylline [479-18-5]; Down 200; 15.8uM; PC3; HT_HG-U133A

SSH3 TSPOAP1 IL4R

1.31e-041961235063_DN
DrugEserine sulfate, physostigmine sulfate [64-47-1]; Down 200; 6.2uM; MCF7; HT_HG-U133A

SSH3 ADAM10 DNMT3A

1.33e-041971232768_DN
DrugSolasodine [126-17-0]; Down 200; 9.6uM; MCF7; HT_HG-U133A

SSH3 ADAM10 DNMT3A

1.33e-041971233924_DN
DrugFlunisolide [3385-03-3]; Down 200; 9.2uM; MCF7; HT_HG-U133A

SSH3 DNMT3A IL4R

1.35e-041981236023_DN
DrugSpironolactone [52-01-7]; Up 200; 9.6uM; HL60; HG-U133A

SSH3 ADAM10 TSPOAP1

1.35e-041981231380_UP
DrugD-cycloserine [68-41-7]; Up 200; 39.2uM; PC3; HT_HG-U133A

SSH3 DNMT3A IL4R

1.37e-041991237134_UP
DiseaseHIV-associated neurocognitive disorder, asymptomatic neurocognitive impairment

NOMO2 IL4R

1.52e-065122EFO_0007948, EFO_0007983
Diseaseprimary biliary cirrhosis

DNMT3A IL4R

1.29e-03133122EFO_1001486
Diseaselymphocyte:monocyte ratio

TSPOAP1 DNMT3A

5.87e-03288122EFO_0600088
DiseaseEczema

DNMT3A IL4R

6.77e-03310122HP_0000964

Protein segments in the cluster

PeptideGeneStartEntry
IAGMNAVEENQGPGE

DNMT3A

221

Q9Y6K1
GQPICGNGMVEQGEE

ADAM10

456

O14672
NGEPEQGVAMEAVGQ

NOMO3

971

P69849
QQAPNTEMCQGGDPG

TSPOAP1

1211

O95153
KQDGGEQNGGMQCKP

FIGNL1

346

Q6PIW4
NGEPEQGVAMEAVGQ

NOMO2

971

Q5JPE7
NGEPEQGVAMEAVGQ

NOMO1

971

Q15155
QCHGQEDGGQTPVMA

IL4R

726

P24394
GQDGNEEMGGITQTP

CD3E

21

P07766
GCGQPQDEGDMENTV

DCST2

601

Q5T1A1
EQEQGQGQGQGEPCI

SSH3

621

Q8TE77
IDQILNSPDQGGCMG

TLX1

21

P31314