Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcesspost-translational protein targeting to endoplasmic reticulum membrane

FOLR1 GLP1R MACF1

3.99e-0521663GO:0006620
GeneOntologyBiologicalProcessRac protein signal transduction

EPS8 FNTA HACD3 TEK

4.07e-0560664GO:0016601
GeneOntologyCellularComponentkainate selective glutamate receptor complex

GRIK4 GRIK5

1.60e-046692GO:0032983
DomainCezanne-2

OTUD7A OTUD7B

1.35e-052692IPR033477
DomainERM_C_dom

RDX MSN

8.03e-054692IPR011259
DomainERM

RDX MSN

8.03e-054692PF00769
DomainERM

RDX MSN

8.03e-054692IPR011174
DomainZnf_A20

OTUD7A OTUD7B

2.79e-047692IPR002653
DomainZF_A20

OTUD7A OTUD7B

2.79e-047692PS51036
Domainzf-A20

OTUD7A OTUD7B

2.79e-047692PF01754
DomainMoesin_tail

RDX MSN

2.79e-047692IPR008954
DomainZnF_A20

OTUD7A OTUD7B

2.79e-047692SM00259
DomainOTU

OTUD7A OTUD7B

1.02e-0313692PF02338
DomainOTU

OTUD7A OTUD7B

1.37e-0315692PS50802
DomainOTU_dom

OTUD7A OTUD7B

1.37e-0315692IPR003323
Domain-

MED16 FSTL5 WDR12 SEC31A LYST SEC13

1.43e-033336962.130.10.10
DomainWD40/YVTN_repeat-like_dom

MED16 FSTL5 WDR12 SEC31A LYST SEC13

1.48e-03335696IPR015943
DomainGal_mutarotase_SF_dom

MGAM MAN2A2

1.76e-0317692IPR011013
DomainCH

SPTBN5 LMO7 MACF1

1.79e-0365693SM00033
DomainIontro_rcpt

GRIK4 GRIK5

1.98e-0318692IPR001320
DomainLig_chan-Glu_bd

GRIK4 GRIK5

1.98e-0318692PF10613
DomainIono_rcpt_met

GRIK4 GRIK5

1.98e-0318692IPR001508
DomainGlu/Gly-bd

GRIK4 GRIK5

1.98e-0318692IPR019594
DomainLig_chan-Glu_bd

GRIK4 GRIK5

1.98e-0318692SM00918
DomainLig_chan

GRIK4 GRIK5

1.98e-0318692PF00060
DomainPBPe

GRIK4 GRIK5

1.98e-0318692SM00079
DomainCH

SPTBN5 LMO7 MACF1

2.21e-0370693PF00307
Domain-

SPTBN5 LMO7 MACF1

2.30e-03716931.10.418.10
DomainCH

SPTBN5 LMO7 MACF1

2.49e-0373693PS50021
DomainWD40

MED16 WDR12 SEC31A LYST SEC13

2.69e-03259695PF00400
DomainCH-domain

SPTBN5 LMO7 MACF1

2.69e-0375693IPR001715
DomainEz/rad/moesin-like

RDX MSN

2.70e-0321692IPR000798
DomainWD40

MED16 WDR12 SEC31A LYST SEC13

3.12e-03268695SM00320
DomainActinin_actin-bd_CS

SPTBN5 MACF1

3.24e-0323692IPR001589
DomainSpectrin

SPTBN5 MACF1

3.24e-0323692PF00435
DomainACTININ_2

SPTBN5 MACF1

3.24e-0323692PS00020
DomainACTININ_1

SPTBN5 MACF1

3.24e-0323692PS00019
Domainzf-CCHC

ERVK-5 ZCCHC7

3.24e-0323692PF00098
DomainWD40_repeat

MED16 WDR12 SEC31A LYST SEC13

3.32e-03272695IPR001680
DomainFERM_CS

RDX MSN

3.52e-0324692IPR019747
DomainWD_REPEATS_1

MED16 WDR12 SEC31A LYST SEC13

3.65e-03278695PS00678
DomainWD_REPEATS_2

MED16 WDR12 SEC31A LYST SEC13

3.70e-03279695PS50082
DomainWD_REPEATS_REGION

MED16 WDR12 SEC31A LYST SEC13

3.70e-03279695PS50294
DomainHormR

GLP1R ADCYAP1R1

3.82e-0325692SM00008
DomainEF_Hand_1_Ca_BS

SLC25A24 TCHH FSTL5 MACF1

4.01e-03175694IPR018247
DomainFERM_C

RDX MSN

4.13e-0326692PF09380
DomainFERM_C

RDX MSN

4.45e-0327692SM01196
DomainFERM_PH-like_C

RDX MSN

4.45e-0327692IPR018980
DomainHRM

GLP1R ADCYAP1R1

4.78e-0328692PF02793
DomainWD40_repeat_dom

MED16 WDR12 SEC31A LYST SEC13

4.82e-03297695IPR017986
DomainSpectrin_repeat

SPTBN5 MACF1

5.12e-0329692IPR002017
DomainSpectrin/alpha-actinin

SPTBN5 MACF1

6.21e-0332692IPR018159
DomainSPEC

SPTBN5 MACF1

6.21e-0332692SM00150
DomainFERM_N

RDX MSN

6.60e-0333692PF09379
DomainFERM_N

RDX MSN

6.60e-0333692IPR018979
DomainEF_HAND_1

SLC25A24 TCHH FSTL5 MACF1

6.87e-03204694PS00018
DomainGPCR_2_secretin-like_CS

GLP1R ADCYAP1R1

6.99e-0334692IPR017983
Pubmed

Genetic ablation of the GluK4 kainate receptor subunit causes anxiolytic and antidepressant-like behavior in mice.

GRIK4 GRIK5

4.11e-06271222203159
Pubmed

High-affinity kainate receptor subunits are necessary for ionotropic but not metabotropic signaling.

GRIK4 GRIK5

4.11e-06271219778510
Pubmed

Epithelial organization and cyst lumen expansion require efficient Sec13-Sec31-driven secretion.

SEC31A SEC13

4.11e-06271222331354
Pubmed

Structure of the Sec13/31 COPII coat cage.

SEC31A SEC13

4.11e-06271216407955
Pubmed

Subunit-specific desensitization of heteromeric kainate receptors.

GRIK4 GRIK5

4.11e-06271220026616
Pubmed

Mammalian homologues of yeast sec31p. An ubiquitously expressed form is localized to endoplasmic reticulum (ER) exit sites and is essential for ER-Golgi transport.

SEC31A SEC13

1.23e-05371210788476
Pubmed

A gene family consisting of ezrin, radixin and moesin. Its specific localization at actin filament/plasma membrane association sites.

RDX MSN

1.23e-0537121429901
Pubmed

The ezrin-like family of tyrosine kinase substrates: receptor-specific pattern of tyrosine phosphorylation and relationship to malignant transformation.

RDX MSN

1.23e-0537128479753
Pubmed

ERM Proteins at the Crossroad of Leukocyte Polarization, Migration and Intercellular Adhesion.

RDX MSN

1.23e-05371232098334
Pubmed

Characterization of lens fiber cell triton insoluble fraction reveals ERM (ezrin, radixin, moesin) proteins as major cytoskeletal-associated proteins.

RDX MSN

1.23e-05371218261459
Pubmed

Ezrin, radixin, and moesin are phosphorylated in response to 2-methoxyestradiol and modulate endothelial hyperpermeability.

RDX MSN

1.23e-05371221659656
Pubmed

Expression, localization, and binding activity of the ezrin/radixin/moesin proteins in the mouse testis.

RDX MSN

1.23e-05371219064715
Pubmed

Activation of PKC induces leukocyte adhesion by the dephosphorylation of ERM.

RDX MSN

1.23e-05371231843195
Pubmed

Ezrin, Radixin, and Moesin (ERM) proteins function as pleiotropic regulators of human immunodeficiency virus type 1 infection.

RDX MSN

1.23e-05371218295815
Pubmed

Dmoesin controls actin-based cell shape and polarity during Drosophila melanogaster oogenesis.

RDX MSN

1.23e-05371212360288
Pubmed

Association study of polymorphisms in the GluR7, KA1 and KA2 kainate receptor genes (GRIK3, GRIK4, GRIK5) with schizophrenia.

GRIK4 GRIK5

1.23e-05371216325263
Pubmed

Differential involvement of ezrin/radixin/moesin proteins in sphingosine 1-phosphate-induced human pulmonary endothelial cell barrier enhancement.

RDX MSN

1.23e-05371221864676
Pubmed

Differential expression of ezrin/radixin/moesin (ERM) and ERM-associated adhesion molecules in the blastocyst and uterus suggests their functions during implantation.

RDX MSN

1.23e-05371214613898
Pubmed

Activation of Ras requires the ERM-dependent link of actin to the plasma membrane.

RDX MSN

1.23e-05371222132106
Pubmed

Dynamics and function of ERM proteins during cytokinesis in human cells.

RDX MSN

1.23e-05371228889652
Pubmed

Increased phosphorylation of ezrin/radixin/moesin proteins contributes to proliferation of rheumatoid fibroblast-like synoviocytes.

RDX MSN

1.23e-05371221278069
Pubmed

Inhibition of cell adhesion by phosphorylated Ezrin/Radixin/Moesin.

RDX MSN

1.23e-05371226555866
Pubmed

Control of adipogenesis by ezrin, radixin and moesin-dependent biomechanics remodeling.

RDX MSN

1.23e-05371223116763
Pubmed

Induction of ezrin-radixin-moesin molecules after cryogenic traumatic brain injury of the mouse cortex.

RDX MSN

1.23e-05371221451358
Pubmed

Human ezrin-moesin-radixin proteins modulate hepatitis C virus infection.

RDX MSN

1.23e-05371223703860
Pubmed

Ezrin-radixin-moesin family proteins are involved in parvovirus replication and spreading.

RDX MSN

1.23e-05371219321616
Pubmed

Pseudomonas aeruginosa ExoS ADP-ribosyltransferase inhibits ERM phosphorylation.

RDX MSN

1.23e-05371216889625
Pubmed

Deciphering brain-specific transcriptomic expression of Ezr, Rad and Msn genes in the development of Mus musculus.

RDX MSN

1.23e-05371229906485
Pubmed

Differential effects of ceramide and sphingosine 1-phosphate on ERM phosphorylation: probing sphingolipid signaling at the outer plasma membrane.

RDX MSN

1.23e-05371220679347
Pubmed

Differential expression and distribution of ezrin, radixin and moesin in human natural killer cells.

RDX MSN

1.23e-05371212385025
Pubmed

Are ERM (ezrin/radixin/moesin) proteins targets for autoantibodies in demyelinating neuropathies?

RDX MSN

1.23e-05371225286001
Pubmed

Nuclear ERM (ezrin, radixin, moesin) proteins: regulation by cell density and nuclear import.

RDX MSN

1.23e-05371215149851
Pubmed

Osmotic cell shrinkage activates ezrin/radixin/moesin (ERM) proteins: activation mechanisms and physiological implications.

RDX MSN

1.23e-05371217977945
Pubmed

Ezrin/radixin/moesin proteins are high affinity targets for ADP-ribosylation by Pseudomonas aeruginosa ExoS.

RDX MSN

1.23e-05371215252013
Pubmed

Ezrin/radixin/moesin proteins differentially regulate endothelial hyperpermeability after thrombin.

RDX MSN

1.23e-05371223729486
Pubmed

Effect of knockdown of ezrin, radixin, and moesin on P-glycoprotein function in HepG2 cells.

RDX MSN

1.23e-05371221837648
Pubmed

ERM-Dependent Assembly of T Cell Receptor Signaling and Co-stimulatory Molecules on Microvilli prior to Activation.

RDX MSN

1.23e-05371232160548
Pubmed

The amino-terminal domains of the ezrin, radixin, and moesin (ERM) proteins bind advanced glycation end products, an interaction that may play a role in the development of diabetic complications.

RDX MSN

1.23e-05371212734202
Pubmed

ERM stable knockdown by siRNA reduced in vitro migration and invasion of human SGC-7901 cells.

RDX MSN

1.23e-05371221352885
Pubmed

Ezrin and moesin function together to promote T cell activation.

RDX MSN

1.23e-05371219124745
Pubmed

Effect of N-(3-phenyl-2-propenyl)-1-deoxynojirimycin on the lectin binding to HIV-1 glycoproteins.

GLT8D1 MAN2A2 COLGALT1

1.82e-05257132283726
Pubmed

Destabilization of Atoh1 by E3 Ubiquitin Ligase Huwe1 and Casein Kinase 1 Is Essential for Normal Sensory Hair Cell Development.

SACS MACF1 BCKDHA PRPS1

1.83e-057671427542412
Pubmed

Site-specific N-glycosylation and oligosaccharide structures of recombinant HIV-1 gp120 derived from a baculovirus expression system.

GLT8D1 MAN2A2 COLGALT1

2.05e-05267138218172
Pubmed

Phosphorylated ERM is responsible for increased T cell polarization, adhesion, and migration in patients with systemic lupus erythematosus.

RDX MSN

2.46e-05471217237445
Pubmed

The ERM proteins interact with the HOPS complex to regulate the maturation of endosomes.

RDX MSN

2.46e-05471221148287
Pubmed

Structural basis for cargo regulation of COPII coat assembly.

SEC31A SEC13

2.46e-05471218692470
Pubmed

Efficient coupling of Sec23-Sec24 to Sec13-Sec31 drives COPII-dependent collagen secretion and is essential for normal craniofacial development.

SEC31A SEC13

2.46e-05471218713835
Pubmed

Rho-ROCK-dependent ezrin-radixin-moesin phosphorylation regulates Fas-mediated apoptosis in Jurkat cells.

RDX MSN

2.46e-05471218941185
Pubmed

Leucine-rich repeat kinase 2 regulates Sec16A at ER exit sites to allow ER-Golgi export.

SEC31A SEC13

2.46e-05471225201882
Pubmed

Mutagenesis of the ezrin-radixin-moesin binding domain of L-selectin tail affects shedding, microvillar positioning, and leukocyte tethering.

RDX MSN

2.46e-05471215178693
Pubmed

Functional binding interaction identified between the axonal CAM L1 and members of the ERM family.

RDX MSN

2.46e-05471212070130
Pubmed

CPI-17 drives oncogenic Ras signaling in human melanomas via Ezrin-Radixin-Moesin family proteins.

RDX MSN

2.46e-05471227793041
Pubmed

The NHE1 Na+/H+ exchanger recruits ezrin/radixin/moesin proteins to regulate Akt-dependent cell survival.

RDX MSN

2.46e-05471215096511
Pubmed

Distribution of kainate receptor subunits at hippocampal mossy fiber synapses.

GRIK4 GRIK5

2.46e-05471212954862
Pubmed

Cortical mechanics and meiosis II completion in mammalian oocytes are mediated by myosin-II and Ezrin-Radixin-Moesin (ERM) proteins.

RDX MSN

2.46e-05471220660156
Pubmed

In Vitro and in Vivo Characterization of Molecular Interactions between Calmodulin, Ezrin/Radixin/Moesin, and L-selectin.

RDX MSN

2.46e-05471219129194
Pubmed

Human immunodeficiency virus (HIV)-1 proteins and cytoskeleton: partners in viral life and host cell death.

RDX MSN

2.46e-05471215818415
Pubmed

NHE-RF, a regulatory cofactor for Na(+)-H+ exchange, is a common interactor for merlin and ERM (MERM) proteins.

RDX MSN

2.46e-0547129430655
Pubmed

Two Sides of the Coin: Ezrin/Radixin/Moesin and Merlin Control Membrane Structure and Contact Inhibition.

RDX MSN

2.46e-05471231018575
Pubmed

Ezrin is a component of the HIV-1 virological presynapse and contributes to the inhibition of cell-cell fusion.

RDX MSN

2.46e-05471224760896
Pubmed

Phosphorylation of ezrin/radixin/moesin proteins by LRRK2 promotes the rearrangement of actin cytoskeleton in neuronal morphogenesis.

RDX MSN

2.46e-05471219890007
Pubmed

Proteomic profiling in pancreatic cancer with and without lymph node metastasis.

RDX MSN

2.46e-05471219152423
Pubmed

The lipid 5-phoshatase SHIP2 controls renal brush border ultrastructure and function by regulating the activation of ERM proteins.

RDX MSN

2.46e-05471228302370
Pubmed

Anoctamin 1 (Tmem16A) Ca2+-activated chloride channel stoichiometrically interacts with an ezrin-radixin-moesin network.

RDX MSN

2.46e-05471222685202
Pubmed

LOK is a major ERM kinase in resting lymphocytes and regulates cytoskeletal rearrangement through ERM phosphorylation.

RDX MSN

2.46e-05471219255442
Pubmed

Normal development of mice and unimpaired cell adhesion/cell motility/actin-based cytoskeleton without compensatory up-regulation of ezrin or radixin in moesin gene knockout.

RDX MSN

2.46e-0547129890997
Pubmed

Spatial regulation of cyclic AMP-Epac1 signaling in cell adhesion by ERM proteins.

RDX MSN

2.46e-05471220855527
Pubmed

STAM adaptor proteins interact with COPII complexes and function in ER-to-Golgi trafficking.

SEC31A SEC13

2.46e-05471219054391
Pubmed

CD43 interaction with ezrin-radixin-moesin (ERM) proteins regulates T-cell trafficking and CD43 phosphorylation.

RDX MSN

2.46e-05471221289089
Pubmed

Developmental expression patterns of kainate receptors in the mouse spinal cord.

GRIK4 GRIK5

4.09e-05571223076118
Pubmed

Interplay between RAGE, CD44, and focal adhesion molecules in epithelial-mesenchymal transition of alveolar epithelial cells.

RDX MSN

4.09e-05571221278261
Pubmed

Activated ERM protein plays a critical role in drug resistance of MOLT4 cells induced by CCL25.

RDX MSN

4.09e-05571223326330
Pubmed

Regulation of NK cell trafficking by CD81.

RDX MSN

4.09e-05571219830727
Pubmed

CCDC102B functions in centrosome linker assembly and centrosome cohesion.

CEP250 CCDC102B

4.09e-05571230404835
Pubmed

Anchoring of protein kinase A by ERM (ezrin-radixin-moesin) proteins is required for proper netrin signaling through DCC (deleted in colorectal cancer).

RDX MSN

4.09e-05571225575591
Pubmed

Determination of kainate receptor subunit ratios in mouse brain using novel chimeric protein standards.

GRIK4 GRIK5

4.09e-05571226448475
Pubmed

Biochemical and assembly properties of GluR6 and KA2, two members of the kainate receptor family, determined with subunit-specific antibodies.

GRIK4 GRIK5

4.09e-0557128288598
Pubmed

Kainate receptors: pharmacology, function and therapeutic potential.

GRIK4 GRIK5

4.09e-05571218793656
Pubmed

The Ca2+-binding protein ALG-2 is recruited to endoplasmic reticulum exit sites by Sec31A and stabilizes the localization of Sec31A.

SEC31A SEC13

4.09e-05571216957052
Pubmed

Complete Disruption of the Kainate Receptor Gene Family Results in Corticostriatal Dysfunction in Mice.

GRIK4 GRIK5

4.09e-05571228228252
Pubmed

Kainate receptor subunits underlying presynaptic regulation of transmitter release in the dorsal horn.

GRIK4 GRIK5

4.09e-05571212223554
Pubmed

A Pak1-PP2A-ERM signaling axis mediates F-actin rearrangement and degranulation in mast cells.

RDX MSN

4.09e-05571223063725
Pubmed

Ezrin/radixin/moesin are required for the purinergic P2X7 receptor (P2X7R)-dependent processing of the amyloid precursor protein.

RDX MSN

4.09e-05571222891241
Pubmed

The TSC1 tumour suppressor hamartin regulates cell adhesion through ERM proteins and the GTPase Rho.

RDX MSN

4.09e-05571210806479
Pubmed

In vitro reconstitution of ER-stress induced ATF6 transport in COPII vesicles.

SEC31A SEC13

4.09e-05571219822759
Pubmed

Molecular determinants of kainate receptor trafficking.

GRIK4 GRIK5

4.09e-05571218358623
Pubmed

Vitronectin induces phosphorylation of ezrin/radixin/moesin actin-binding proteins through binding to its novel neuronal receptor telencephalin.

RDX MSN

4.09e-05571223019340
Pubmed

Sensitivity of CYP1A1 mRNA inducibility by dioxin is the same in Cyp1a2(+/+) wild-type and Cyp1a2(-/-) null mutant mice.

RDX MSN

4.09e-0557129464455
Pubmed

Development of laminar distributions of kainate receptors in the somatosensory cortex of mice.

GRIK4 GRIK5

4.09e-0557129593973
Pubmed

Preferential assembly of heteromeric kainate and AMPA receptor amino terminal domains.

GRIK4 GRIK5

4.09e-05571229058671
Pubmed

A novel role for BRCA1 in regulating breast cancer cell spreading and motility.

RDX MSN

4.09e-05571221282464
Pubmed

Sequential genome-wide CRISPR-Cas9 screens identify genes regulating cell-surface expression of tetraspanins.

KIAA0408 SLC25A24 GALE SUPT6H SPATA18 TERF1 GSC HERC5 STEAP1

4.86e-0583271936724073
Pubmed

Diversification of stem cell molecular repertoire by alternative splicing.

MED16 DOCK8 WAC

5.09e-053571316183747
Pubmed

Intracellular mannose binding lectin mediates subcellular trafficking of HIV-1 gp120 in neurons.

SEC31A SEC13

6.13e-05671224825317
Pubmed

Human immunodeficiency virus (HIV-1) Vpr induced downregulation of NHE1 induces alteration in intracellular pH and loss of ERM complex in target cells.

RDX MSN

6.13e-05671217349711
Pubmed

Gene expression in temporal lobe epilepsy is consistent with increased release of glutamate by astrocytes.

RDX MSN

6.13e-05671217515952
Pubmed

N-glycan content modulates kainate receptor functional properties.

GRIK4 GRIK5

6.13e-05671228714086
Pubmed

Intracellular sphingosine kinase 2-derived sphingosine-1-phosphate mediates epidermal growth factor-induced ezrin-radixin-moesin phosphorylation and cancer cell invasion.

RDX MSN

6.13e-05671226209696
Pubmed

The TSC1 tumor suppressor hamartin interacts with neurofilament-L and possibly functions as a novel integrator of the neuronal cytoskeleton.

RDX MSN

6.13e-05671212226091
Pubmed

Expression of ezrin in subventricular zone neural stem cells and their progeny in adult and developing mice.

RDX MSN

6.13e-05671223229862
Cytoband8q21.11

TERF1 CRISPLD1

8.68e-04287128q21.11
GeneFamilyGlutamate ionotropic receptor kainate type subunits

GRIK4 GRIK5

6.58e-0554721199
GeneFamilyWD repeat domain containing

MED16 WDR12 SEC31A LYST SEC13

5.74e-04262475362
GeneFamilyOTU domain containing

OTUD7A OTUD7B

8.77e-0417472669
GeneFamilyEF-hand domain containing

SLC25A24 TCHH FSTL5 MACF1

2.48e-03219474863
GeneFamilyAnkyrin repeat domain containing|FERM domain containing

RDX MSN

7.48e-03504721293
GeneFamilyGATA zinc finger domain containing|Myb/SANT domain containing

EP400 TERF1

8.38e-0353472532
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_VWA2|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FSTL5 GRIK4 C8orf34 CRISPLD1 ADCYAP1R1 PCNT

4.27e-0718270672e65a23cd36085bc880087d3cae92395de918a1
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FSTL5 GRIK4 C8orf34 CRISPLD1 ADCYAP1R1 PCNT

4.27e-0718270605c167158815bf25d509df59ab386e1990712765
ToppCellCOPD-Endothelial-VE_Venous|Endothelial / Disease state, Lineage and Cell class

EPS8 MROH2B KAZN TEK LYST

9.25e-06179705e816dd846a6918ec143b57a380c3a47ed073b66e
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_SST_CXCL14|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

EPS8 FSTL5 GRIK4 ANKFN1 C8orf34

9.51e-06180705b6efdb4d319ef6f87f559acd974e5a71b06a2322
ToppCellASK454-Epithelial|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq

KIAA0408 LMO7 FOLR1 RDX CCDC102A

1.00e-05182705ab15316cff989b61ff397a866d7ca8b49c13e981
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

EPS8 GALE LMO7 KAZN VARS2

1.00e-0518270517ed11a7ea366dd3106400511d5e628d3f1a9c3e
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2-AT2_Progenitor|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

EPS8 GALE LMO7 KAZN VARS2

1.06e-05184705d0c212a8fbaad24597a84018442b25c61c17ea58
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

EPS8 FSTL5 ANKFN1 C8orf34 ADCYAP1R1

1.09e-0518570508fad1e3c3cc5f1c3eb6629a49c094b628e75a92
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADAMTS12 KIAA0408 SFRP4 FSTL5 CRISPLD1

1.09e-051857053b2dfc8f4c87be516265dbecfc251276034d0efd
ToppCellCOVID-19_Moderate-NK_activated|World / disease group, cell group and cell class

MGAM GLP1R GRIK4 HERC5 CCDC102A

1.11e-05186705ff8f32f69516bf785224fa12f8139a95359b0279
ToppCellLPS_IL1RA_TNF|World / Treatment groups by lineage, cell group, cell type

ADAMTS12 KIAA0408 LMO7 VARS2 C8orf34

1.47e-051977050a6550dce156fc81f15b1e7830d331ca50d87d06
ToppCellIPF-Stromal-Myofibroblast|Stromal / Disease state, Lineage and Cell class

ADAMTS12 MACF1 GRIK4 CCDC102B STEAP1

1.47e-05197705f304d42fc4936fe20996e07c8dccc698a6e5e5ef
ToppCellNeuronal-Inhibitory-iA|Neuronal / cells hierarchy compared to all cells using T-Statistic

EPS8 FSTL5 KAZN C8orf34 ADCYAP1R1

1.58e-052007055ef4a3dc18a44292184a59ced916183c0699b01e
ToppCellPND01-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FBXO43 ANKFN1 AK7 STEAP1

9.41e-05151704e335dad89e0a44cdd302b9653154ba5d1ee5fe1a
ToppCellPND01-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal-Deuterosomal_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FBXO43 ANKFN1 AK7 STEAP1

9.41e-05151704633ed52dd3b4cf1e87432cf0a1ca187d7b204e83
ToppCellHippocampus-Macroglia-CSF_related|Hippocampus / BrainAtlas - Mouse McCarroll V32

FOLR1 SPATA18 AK7 STEAP1

9.65e-05152704c2b6cc41546cbd46b9ea5d28a7c66f6330a27df2
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Granulocytic-Neutrophil-Neu_c6-FGF23|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

MGAM DOCK8 UNKL DDX43

9.65e-051527040652ee3443e6fbb679d2c4f326239ae7c803f924
ToppCellCOVID-19-kidney-Technical/muscle_(Mes)|kidney / Disease (COVID-19 only), tissue and cell type

FSTL5 GRIK4 ANKFN1 C8orf34

1.15e-041597045335cbcdeaf2bbd0268bbfe0e45c8c0d288e640d
ToppCell3'_v3-GI_small-bowel-Lymphocytic_NK-NK_CD16|GI_small-bowel / Manually curated celltypes from each tissue

MGAM GLP1R GRIK4 LYST

1.55e-04172704701de463f85aaad3a4b36a0d5fbc416406620089
ToppCell(0)_Normal/No_Treatment-(4)_COL2.3+_osteoblasts|(0)_Normal/No_Treatment / Stress and Cell class

GALE GLT8D1 LMO7 SEC13

1.59e-04173704c2a0f674681836b5a868c13f67caa7d555ef6519
ToppCellPCW_10-12-Epithelial-Epithelial_ciliated|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

SPATA18 ANKFN1 C8orf34 AK7

1.62e-04174704b8d1c556290d188f56aeefc17f03119686945fe7
ToppCellPND03-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SPATA18 FBXO43 AK7 STEAP1

1.62e-04174704179a52d77899a929396b98d4ab2c270dd2ec708e
ToppCellPCW_10-12-Epithelial-Epithelial_ciliated-epi_ciliated_(14)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

SPATA18 ANKFN1 C8orf34 AK7

1.62e-0417470400cf27bc23af1472a507be31fba6245a8fdd901b
ToppCellPND03-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal-Deuterosomal_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SPATA18 FBXO43 AK7 STEAP1

1.62e-041747049165a1094d345328e58962f4b2a20334c3e93ead
ToppCellPCW_13-14-Epithelial-Epithelial_ciliated|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

SPATA18 ANKFN1 C8orf34 AK7

1.66e-04175704b1369d2b74f461e6822d0c33e9b50fe0dfbceb54
ToppCellPCW_13-14-Epithelial-Epithelial_ciliated-epi_ciliated_(14)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

SPATA18 ANKFN1 C8orf34 AK7

1.66e-04175704c82ec6deb6ccdd991a69a62b6d62d5b14c803d7a
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-early_pro_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPS8 GLP1R GKAP1 PTDSS2

1.70e-041767047292e014b8f697f0c2e9f47c48333de95cb44a69
ToppCellPND10-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SPATA18 FBXO43 AK7 STEAP1

1.70e-04176704d6d7e4e937d49a5c0d16322c8dd3bf9e97eb8732
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-early_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPS8 GLP1R GKAP1 PTDSS2

1.70e-0417670488ca2f83d8301633232735f39b0683efe49d0b86
ToppCellPND10-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal-Deuterosomal_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SPATA18 FBXO43 AK7 STEAP1

1.70e-04176704c03d80df2550c0d2b0452326480d6bf21d20fdd2
ToppCell3'_v3-GI_small-bowel-Lymphocytic_NK|GI_small-bowel / Manually curated celltypes from each tissue

MGAM GLP1R GRIK4 LYST

1.81e-04179704535bdfdd990ba9ee3edc8f3ad15297f8fb5a266e
ToppCellLPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADAMTS12 KIAA0408 SFRP4 CRISPLD1

1.81e-0417970402c90d8306016365ed811f0c63cfb3ac7b85464c
ToppCellfacs-SCAT|facs / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SFRP4 GSC CRISPLD1 STEAP1

1.85e-041807046c70b6b7480507fa94625013222ad338ee7dd1d9
ToppCellfacs-GAT-Fat-3m-Epithelial-epithelial_cell|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOLR1 SPATA18 ANKFN1 AK7

1.89e-04181704e97cbaafb93fdbee8e3cf4a06e6bcf121d941403
ToppCellCOVID-19-Heart-Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

ADAMTS12 EPS8 CCDC102B ADCYAP1R1

1.89e-0418170433cac65ed1ea5e7bd72250495df4f850b143d5aa
ToppCellfacs-GAT-Fat-3m-Epithelial|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOLR1 SPATA18 ANKFN1 AK7

1.89e-0418170411cb84528f7ca084f0a92eda4f2e18e63a428fe9
ToppCellfacs-GAT-Fat-3m-Epithelial-nan|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOLR1 SPATA18 ANKFN1 AK7

1.89e-041817045ffeca29e4d31a20c110d27af128ed024a79ad56
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

EPS8 FSTL5 ANKFN1 C8orf34

1.93e-041827047dc61e901428cea04f00ebb0939a44d21a6145c6
ToppCelldroplet-Lung-30m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LMO7 GRIK5 TEK AK7

1.97e-041837046f8f997ffc9eaebca2683de125b6069d07c07d26
ToppCellTCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Classical-1|TCGA-Thryoid / Sample_Type by Project: Shred V9

ADAMTS12 SFRP4 COLGALT1 STEAP1

1.97e-0418370406e4b05d86a7d643569e19575c2c9aa351d33f29
ToppCellLPS_only-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADAMTS12 KIAA0408 SFRP4 CRISPLD1

1.97e-0418370412daaea821e49bc94a01e2496331e92a80d27339
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_ADARB2_ADAM33|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

EPS8 FSTL5 ANKFN1 C8orf34

1.97e-041837045e361be3ae3fe05098968e58427630127bd12675
ToppCelldroplet-Marrow-nan-3m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK8 MACF1 ZCCHC7 LYST

2.01e-041847041154a5ad7b8512272b7476f949ddac350910bfb7
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_ADARB2_ADAM33|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

EPS8 FSTL5 ANKFN1 C8orf34

2.05e-04185704487fa382232564f075960899d50afa0edae5d258
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GALE LMO7 KAZN VARS2

2.05e-04185704fefaf227d89f680d6f3e91c4a94e26ab4d0dc6c3
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_2-AT2_Progenitor|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GALE LMO7 KAZN VARS2

2.05e-04185704929b68b05b7686341329ac756d7df172cb4b810b
ToppCellCOVID-19-Epithelial_cells-Airway_ciliated|COVID-19 / group, cell type (main and fine annotations)

SPATA18 ANKFN1 C8orf34 AK7

2.05e-0418570418a40f0a338aa398d81384b5159fb80ce8a2020c
ToppCelldroplet-Heart-nan-3m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SACS LMO7 TEK LYST

2.10e-041867040ae5fbe9f210cb25092394267e1d3d6ed05627b8
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

EPS8 LMO7 KAZN VARS2

2.10e-04186704e83718fabb057100835d3357df407f283d23fe16
ToppCellfacs-Lung-EPCAM-3m-Epithelial-Ciliated_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPATA18 ANKFN1 C8orf34 AK7

2.14e-0418770404dba2ed09ee4180830bdf0191921696697ea234
ToppCellPND03|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LMO7 LYST AK7 MSN

2.14e-04187704b3fcb36d853adfdea7172c5591de06f027e50af3
ToppCellCOPD-Epithelial-Ciliated|COPD / Disease state, Lineage and Cell class

SPATA18 ANKFN1 C8orf34 AK7

2.14e-04187704f0fd0792f6926f705d175f6e6fd480f12c7a3bd4
ToppCellControl-Fibroblasts-Alveolar_FB|Control / group, cell type (main and fine annotations)

ADAMTS12 MACF1 GRIK4 CCDC102B

2.14e-0418770492d468dde81125d51daf7abd4703741abe1ab91c
ToppCellfacs-Lung-EPCAM-3m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPATA18 ANKFN1 C8orf34 AK7

2.14e-04187704805dafe22f835ece4dd091d8030d0a63b52a48dd
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_ADARB2_ADAM33|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

EPS8 FSTL5 ANKFN1 C8orf34

2.14e-0418770402105c82a9ba79d2f19e002188377fc3440770c2
ToppCellfacs-Heart-RA-3m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPS8 GLP1R RDX TEK

2.18e-041887044ddb11a90bf3baa7237bde304db44dfcc56aed52
ToppCellfacs-Heart-RA-3m-Endothelial-endothelial_cell_of_endocardium|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPS8 GLP1R RDX TEK

2.18e-04188704e47e66906922d5c69b1aafe28face0787d3fc563
ToppCellASK454-Epithelial-Type_1|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq

KIAA0408 LMO7 FOLR1 RDX

2.18e-0418870413f8ce8f24ac7d7ed87f4ae3b8f4096de29383c2
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Colon_Adenocarcinoma-7|TCGA-Colorectal / Sample_Type by Project: Shred V9

ADAMTS12 SFRP4 CEP250 ZMYM2

2.18e-0418870414bc73cf79c79c9f208369fd8d498e5b26e0114d
ToppCellCOVID-19_Moderate-NK_activated|COVID-19_Moderate / disease group, cell group and cell class

MGAM GLP1R GRIK4 CCDC102A

2.23e-041897048f9f1e71857bed6d59c4b087b6a6970f30fd86be
ToppCellEntopeduncular-Macroglia-POLYDENDROCYTE-P1-P1_2|Entopeduncular / BrainAtlas - Mouse McCarroll V32

MROH2B ANKFN1 STEAP1

2.25e-04757039a82db6281326acc534b800e02b262a8617a147e
ToppCellEntopeduncular-Macroglia-POLYDENDROCYTE-P1-P1_2-Tnr-Polydendrocyte.Tnr.Pdgfa_(Pdgfa)|Entopeduncular / BrainAtlas - Mouse McCarroll V32

MROH2B ANKFN1 STEAP1

2.25e-04757037678e7d514560c774b56fc0a20312d561c89f587
ToppCellEntopeduncular-Macroglia-POLYDENDROCYTE-P1-P1_2-Tnr|Entopeduncular / BrainAtlas - Mouse McCarroll V32

MROH2B ANKFN1 STEAP1

2.25e-04757037f1fc575fca42352434f7188c7a95b50372aeefa
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FSTL5 KAZN C8orf34 ADCYAP1R1

2.27e-0419070456cc761e50fddfb5366391518b4d8e16589b6b42
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_1|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FSTL5 KAZN C8orf34 ADCYAP1R1

2.27e-0419070425d4b591f75c26e404a34c42f1742d580af6598d
ToppCell(5)_Fibroblasts-(5)_Fibroblast-C_(Myofibroblast)|(5)_Fibroblasts / Lung cell shreds - cell class (v4) and cell subclass (v4)

ADAMTS12 MACF1 GRIK4 CCDC102B

2.27e-0419070471e112dfb8c3190fe0286b45a046ea789eb6a8db
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro1_(4)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ADAMTS12 GRIK4 CCDC102B C8orf34

2.32e-04191704fa380a8752de158974b2ae5e741573439719cc0d
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-Pecam____Kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OTUD7A TEK CRISPLD1 ADCYAP1R1

2.32e-04191704b9ae5af426e7a1f2652a47700bb168371bd2dec6
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ADAMTS12 MACF1 GRIK4 CCDC102B

2.32e-041917046688cee34beee4f151ac17fccbc9c26a9aad72e1
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ADAMTS12 MACF1 GRIK4 CCDC102B

2.36e-0419270499ce9e3c4c50cf64ebb62145f2b5420efa0db309
ToppCellAdult-Mesenchymal-matrix_fibroblast_2_cell|Adult / Lineage, Cell type, age group and donor

KAZN CCDC102B ANKFN1 STEAP1

2.36e-04192704d21f0f577156f17c899b08871046a26b88aea011
ToppCellIPF-Epithelial-Ciliated|World / Disease state, Lineage and Cell class

SPATA18 ANKFN1 C8orf34 AK7

2.36e-04192704d903bbd6c18e29e2c4cdedeb3fea1fd5ad7baa11
ToppCellCOPD-Epithelial-Ciliated|World / Disease state, Lineage and Cell class

SPATA18 ANKFN1 C8orf34 AK7

2.36e-04192704eab1105cd1a98cfcd3d74dc5c9b89e1799bba59e
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FSTL5 KAZN C8orf34 ADCYAP1R1

2.36e-04192704bf1943715085c4124b1675888b0615c9500ec888
ToppCellIPF-Epithelial-Ciliated|IPF / Disease state, Lineage and Cell class

SPATA18 ANKFN1 C8orf34 AK7

2.36e-04192704354adc1354bf596fbc60dd45c0169688e6f45165
ToppCellCOPD-Stromal-Myofibroblast|Stromal / Disease state, Lineage and Cell class

ADAMTS12 MACF1 GRIK4 CCDC102B

2.36e-0419270462904f94dfce430456f05066522cbf9bd29f4d7e
ToppCellIPF-Epithelial-Ciliated|Epithelial / Disease state, Lineage and Cell class

SPATA18 ANKFN1 C8orf34 AK7

2.41e-04193704ad58f5080e0ba65c845056ea6b79037b636e9c64
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

ADAMTS12 MACF1 GRIK4 CCDC102B

2.41e-0419370499525545552b371c86b18b6ea6f4897dc6e9a9ec
ToppCellControl-Stromal-Myofibroblast|Stromal / Disease state, Lineage and Cell class

ADAMTS12 MACF1 GRIK4 CCDC102B

2.41e-041937045896242f713ae5fd1a4ebb63827f15d7279dced2
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia_independent-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

HACD3 RDX SEC31A STEAP1

2.46e-04194704f44394c8a6f86483063f2f5722f003a8a0a70254
ToppCellControl-Epithelial-Ciliated|World / Disease state, Lineage and Cell class

SPATA18 ANKFN1 C8orf34 AK7

2.46e-04194704958e648138676d46698090b4046cb484083ae449
ToppCellDiffer-Basal|World / shred by cell class for mouse tongue

TCHH GALE LMO7 DOCK8

2.46e-04194704851eff82c9f3d44c86e3e127a804bbd1fced6a7c
ToppCellIPF-Multiplet-Multiplet|IPF / Disease state, Lineage and Cell class

LMO7 ANKFN1 C8orf34 AK7

2.51e-04195704fce0c29574bb7aab181b9c00feb42681e285d1f2
ToppCellIPF-Multiplet-Multiplet|World / Disease state, Lineage and Cell class

SPATA18 ANKFN1 C8orf34 AK7

2.51e-0419570421dbdc803c6947024dc2416e9e21c2ef0af9bc31
ToppCellCOVID-19-Fibroblasts-Alveolar_FB|COVID-19 / group, cell type (main and fine annotations)

ADAMTS12 GRIK4 KAZN CCDC102B

2.51e-04195704603050beeb33c331d4b2e3fa46cae3f3e0e4bdc7
ToppCellIPF-Multiplet|IPF / Disease state, Lineage and Cell class

LMO7 ANKFN1 C8orf34 AK7

2.51e-04195704eacc0449ae6f3ad8002268cd061467684c6fb9a7
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Granulocytic-Neutrophil|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

MGAM FNTA DOCK8 LYST

2.56e-04196704fe8d3f45a64323947c36b127355d5940eb56c0ca
ToppCellCOPD-Multiplet-Multiplet|COPD / Disease state, Lineage and Cell class

LMO7 SPATA18 MACF1 C8orf34

2.56e-04196704af4cdc61830685a888a1209826c23bcf54a43084
ToppCellfacs-Skin-Telogen-3m-Epithelial-outer_bulge|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPS8 LMO7 MACF1 MSN

2.56e-04196704c936014125b2ed5f796221b74acb77b8f8359875
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FSTL5 KAZN C8orf34 ADCYAP1R1

2.56e-041967047af6c5147ac859353504d19727dbe24f63a29dd4
ToppCellCOPD-Multiplet|COPD / Disease state, Lineage and Cell class

LMO7 SPATA18 MACF1 C8orf34

2.56e-041967046d02d494196e3f857d53eea46d9419690d43beca
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Granulocytic|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

MGAM FNTA DOCK8 LYST

2.56e-04196704526d037bb12d81f1c235c60ddc787fbad0bbad77
ToppCellIPF-Epithelial|IPF / Disease state, Lineage and Cell class

LMO7 SPATA18 ANKFN1 C8orf34

2.56e-0419670487d9881cfec461a5d89b688a83749b618c519485
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature3_(17)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

ADAMTS12 MACF1 GRIK4 KAZN

2.61e-0419770431a1852911bda38543916585fda34255fd62a134
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS12 EPS8 KAZN CCDC102B

2.61e-0419770485a8f1d18e0dd1d31341f5131eecd217553bf042
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS12 EPS8 KAZN CCDC102B

2.61e-04197704e8e3ba791dfaa0fab35e0329a5e34376f9ee6143
ToppCellBL|World / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

MGAM DOCK8 LYST MSN

2.61e-041977041acf0191fa0a25cd20bfd9ea7bf727a1555986a1
ToppCellASK440-Epithelial-Type_1|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq

KIAA0408 LMO7 FOLR1 RDX

2.61e-041977041eda2c2504451a3d626dda5c2b2b12eeaa6bca54
ToppCellASK440-Epithelial-Type_1|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq

KIAA0408 LMO7 FOLR1 RDX

2.61e-04197704782449c522c9e16e72bf999a73090688a3aefe06
ToppCellASK428-Epithelial-Type_1|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq

KIAA0408 LMO7 FOLR1 RDX

2.61e-041977049ae6661c307791c3f0ecd3d378e3d917565e5498
Drugpyrimidine-2,4-dione

MGAM GRIK4 GRIK5

2.77e-075703CID000150747
Druggamma-Glu-Gly

MGAM GRIK4 GRIK5 PCNT

5.01e-0637704CID000100099
DrugAC1L1K9N

MGAM GRIK4 GRIK5

7.79e-0613703CID000005398
Diseaseattempted suicide

FSTL5 OTUD7A WDR12 GRIK4 KAZN

5.79e-05178685EFO_0004321
DiseaseIntellectual Disability

GALE SACS DOCK8 FOLR1 ZMYM2 MACF1 WAC

7.64e-05447687C3714756
DiseaseColorectal Carcinoma

SFRP4 SACS LMO7 FSTL5 C8orf34 WAC PRPS1

1.15e-03702687C0009402
Diseaseresponse to angiotensin receptor blocker

EPS8 FSTL5

2.18e-0330682EFO_0010735
DiseaseParkinsonian Disorders

POLG LYST

2.18e-0330682C0242422

Protein segments in the cluster

PeptideGeneStartEntry
NEKNRPKDWSEVTIW

BHLHB9

206

Q6PI77
DWQNTDKAVNWLRKE

ARSK

176

Q6UWY0
WEFWNLKTLQEREAR

EP400

2196

Q96L91
KWNWRTKPQSRDFDE

C8orf34

211

Q49A92
PVQKDSREENWQEWR

GKAP1

101

Q5VSY0
ISQKQELWREKWERH

ADAMTS12

216

P58397
HKLTKEQWEERIQNW

RDX

161

P35241
EKEALKRRWRWQQTQ

OTUD7B

226

Q6GQQ9
VWTNQRVLKWVRDID

KAZN

611

Q674X7
VSQWWERLTKQEKRP

HACD3

86

Q9P035
HRIWQKLRAEEQTWQ

GGNBP2

311

Q9H3C7
NNEVQLEFRKSWERW

GLP1R

406

P43220
WSLEERKREQWNSLK

SPATA18

201

Q8TC71
FRNSTAKWWKREIEE

MGAM

1386

O43451
ETARKSQWKKWEVVA

POLG

1031

P54098
DNERKEWESQWKIMQ

KIAA0408

26

Q6ZU52
SRWVWDQEEERKRQE

LMO7

1221

Q8WWI1
HKLNKDQWEERIQVW

MSN

161

P26038
QEEKMWRQEEKIQEW

GOLGA6L6

286

A8MZA4
WRQEEKIQEWEEKIQ

GOLGA6L6

291

A8MZA4
TEWKRQNITNQLEKW

GLT8D1

251

Q68CQ7
RWQQTQQNKEEEWER

OTUD7A

251

Q8TE49
PAAAEQWRKWQRDKE

PCNT

2901

O95613
ESWRKKWNVICNRSI

LRRC66

271

Q68CR7
DRKWGQIQKWLEDSE

LRRFIP2

66

Q9Y608
NWKKIQEELNSRWER

MACF1

4546

Q9UPN3
EVQAEIKRKWRSWKV

ADCYAP1R1

406

P41586
LKAEEWPWNRKNRQI

FSTL5

786

Q8N475
NRTTAVKQWEQRWIK

MED16

811

Q9Y2X0
VKQWEQRWIKNCLAV

MED16

816

Q9Y2X0
VKRWIADVETKRWQS

HERC5

396

Q9UII4
WKVSRNWREIVVQDK

FBXO43

526

Q4G163
LDRMCEDLWRWQKQN

GALE

326

Q14376
FKTWWIDGVQEQVRK

ERVK-5

366

Q9HDB9
LRWKKEQTHWRQANE

DOCK8

1396

Q8NF50
RWIWSRESQKEVEKE

CCDC127

41

Q96BQ5
WWIAKQRGKRAITDN

CRISPLD1

46

Q9H336
TANWREKWSKVRAER

CCDC102A

101

Q96A19
NQLREKWEKERSWHQ

CEP250

856

Q9BV73
EIKEVHKRWWQLRDN

LYST

3071

Q99698
KWWDNINVQKRAAVR

MAN2A2

221

P49641
EEKVEVWFKNRRAKW

GSC

201

P56915
LDDRKQWWKVRNASG

EPS8

561

Q12929
QENNRLEILKRKWWE

GRIK4

771

Q16099
VWNNEHVKTDWDRAK

COLGALT1

576

Q8NBJ5
ENNRLEILKRKWWEG

GRIK5

771

Q16478
TDNRRSIKWRELDQW

SACS

471

Q9NZJ4
NWREKWSKVRAERNS

CCDC102B

101

Q68D86
IDWDQIREEGLKWQK

DDX43

171

Q9NXZ2
WIQQVDQSWRKERVL

FOLR1

116

P15328
QGWWDEEQEKAWRKQ

BCKDHA

371

P12694
RKVIIWREENGTWEK

SEC13

81

P55735
REAFLREVWQWKEAK

VARS2

211

Q5ST30
FWNLWRSQIEQKKER

SFI1

421

A8K8P3
RQWVIQEFKLWDNEL

FNTA

206

P49354
KETRWQKWQNKDDQG

PTDSS2

441

Q9BVG9
QWEKPKEWLEREQRQ

WAC

156

Q9BTA9
WLVSQKEWERERAFQ

MROH2B

896

Q7Z745
QWLRAELEAREKLWQ

SPTBN5

1986

Q9NRC6
QQNKEDAWIEHDVWR

STEAP1

201

Q9UHE8
KIRENNNISREEWEW

ANKFN1

641

Q8N957
VWQWDEKWTQLRIRK

SUPT6H

396

Q7KZ85
WRDQLSKRSIQWEER

SFRP4

276

Q6FHJ7
RARKRQAWLWEEDKN

TERF1

376

P54274
QDVTREWAKKVVWKR

TEK

76

Q02763
EAKRKIRQWEESWQQ

UNKL

576

Q9H9P5
VNAWKHWVKTRQLDE

ZMYM2

1076

Q9UBW7
RASWKSNRWPQENKE

ZCCHC7

431

Q8N3Z6
VLKWIRENISEWRNC

PRPS1

151

P60891
TILLWEWNVERNKVK

WDR12

166

Q9GZL7
NWKEIVESCDLKNWR

SEC31A

636

O94979
QEQRRDQKWRWQLEE

TCHH

866

Q07283
EDEKKSGQWWRQLLA

SLC25A24

186

Q6NUK1
KIARWEEWNKRLEEV

AK7

651

Q96M32