Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	translation elongation factor activity	EEF1A1 EEF1A1P5 EEF1A2	3.44e-05	20	64	3	GO:0003746
GeneOntologyMolecularFunction	eukaryotic initiation factor eIF2 binding	NCK1 EIF2AK3	6.04e-05	4	64	2	GO:0071074
GeneOntologyMolecularFunction	translation factor activity, RNA binding	GCN1 EEF1A1 EEF1A1P5 EEF1A2	1.60e-04	85	64	4	GO:0008135
GeneOntologyMolecularFunction	translation regulator activity, nucleic acid binding	GCN1 EEF1A1 EEF1A1P5 EEF1A2	4.60e-04	112	64	4	GO:0090079
GeneOntologyMolecularFunction	cell adhesion molecule binding	CD1D PTPRJ CD226 CDHR3 NCK1 ADAMTS13 AHSA1 GCN1	6.31e-04	599	64	8	GO:0050839
GeneOntologyMolecularFunction	signaling receptor complex adaptor activity	MAGI2 NCK1 NCK2	6.93e-04	54	64	3	GO:0030159
GeneOntologyBiologicalProcess	eiF2alpha phosphorylation in response to endoplasmic reticulum stress	NCK1 EIF2AK3 NCK2	1.65e-06	8	65	3	GO:0036492
GeneOntologyBiologicalProcess	regulation of translation initiation in response to endoplasmic reticulum stress	NCK1 EIF2AK3 NCK2	1.65e-06	8	65	3	GO:0036491
GeneOntologyBiologicalProcess	positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway	NCK1 EIF2AK3 NCK2	6.44e-06	12	65	3	GO:1902237
GeneOntologyBiologicalProcess	regulation of translation in response to endoplasmic reticulum stress	NCK1 EIF2AK3 NCK2	8.35e-06	13	65	3	GO:0036490
GeneOntologyBiologicalProcess	regulation of translational initiation by eIF2 alpha phosphorylation	NCK1 EIF2AK3 NCK2	1.32e-05	15	65	3	GO:0010998
GeneOntologyBiologicalProcess	integrated stress response signaling	NCK1 GCN1 EIF2AK3 NCK2	1.71e-05	49	65	4	GO:0140467
GeneOntologyBiologicalProcess	regulation of phosphorylation	EPHB2 IL24 NLRP12 IL22RA2 PTPRJ CNKSR3 NCK1 EIF2AK3 LEPR IL6ST NCK2 EEF1A1 EEF1A2 FBXW7	2.24e-05	1226	65	14	GO:0042325
GeneOntologyBiologicalProcess	ER-nucleus signaling pathway	NCK1 EIF2AK3 NCK2 FBXW7	2.34e-05	53	65	4	GO:0006984
GeneOntologyBiologicalProcess	regulation of translational initiation in response to stress	NCK1 EIF2AK3 NCK2	2.36e-05	18	65	3	GO:0043558
GeneOntologyBiologicalProcess	regulation of phosphate metabolic process	EPHB2 IL24 MAGI2 NLRP12 IL22RA2 PTPRJ CNKSR3 NCK1 EIF2AK3 LEPR IL6ST NCK2 EEF1A1 EEF1A2 FBXW7	2.71e-05	1421	65	15	GO:0019220
GeneOntologyBiologicalProcess	regulation of phosphorus metabolic process	EPHB2 IL24 MAGI2 NLRP12 IL22RA2 PTPRJ CNKSR3 NCK1 EIF2AK3 LEPR IL6ST NCK2 EEF1A1 EEF1A2 FBXW7	2.76e-05	1423	65	15	GO:0051174
GeneOntologyBiologicalProcess	negative regulation of endoplasmic reticulum unfolded protein response	NCK1 BFAR NCK2	2.79e-05	19	65	3	GO:1900102
GeneOntologyBiologicalProcess	PERK-mediated unfolded protein response	NCK1 EIF2AK3 NCK2	3.81e-05	21	65	3	GO:0036499
GeneOntologyBiologicalProcess	regulation of protein modification process	EPHB2 IL24 MAGI2 NLRP12 RAB3GAP1 IL22RA2 PTPRJ CNKSR3 NCK1 EIF2AK3 KAT14 LEPR IL6ST NCK2 FBXW7	4.63e-05	1488	65	15	GO:0031399
GeneOntologyBiologicalProcess	negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation	NCK1 NCK2	5.84e-05	4	65	2	GO:1903912
GeneOntologyBiologicalProcess	enzyme-linked receptor protein signaling pathway	EPHB2 MAGI2 DOK6 KANK1 ZFYVE9 PTPRJ NCK1 IGSF1 EIF2AK3 HCK IL6ST RYR1 NCK2	7.03e-05	1186	65	13	GO:0007167
GeneOntologyBiologicalProcess	peptidyl-tyrosine phosphorylation	EPHB2 IL24 IL22RA2 PTPRJ HCK IL6ST FBXW7	7.47e-05	327	65	7	GO:0018108
GeneOntologyBiologicalProcess	peptidyl-tyrosine modification	EPHB2 IL24 IL22RA2 PTPRJ HCK IL6ST FBXW7	7.76e-05	329	65	7	GO:0018212
GeneOntologyBiologicalProcess	positive regulation of cell activation	EPHB2 RIF1 CD1D PTPRJ CD226 NCK1 IL6ST NCK2	8.07e-05	449	65	8	GO:0050867
GeneOntologyBiologicalProcess	regulation of translation in response to stress	NCK1 EIF2AK3 NCK2	9.25e-05	28	65	3	GO:0043555
GeneOntologyBiologicalProcess	positive regulation of intrinsic apoptotic signaling pathway	NCK1 EIF2AK3 NCK2 FBXW7	9.72e-05	76	65	4	GO:2001244
GeneOntologyBiologicalProcess	positive regulation of translation in response to endoplasmic reticulum stress	NCK1 NCK2	9.72e-05	5	65	2	GO:0036493
GeneOntologyBiologicalProcess	endoplasmic reticulum unfolded protein response	NCK1 BFAR EIF2AK3 NCK2	1.50e-04	85	65	4	GO:0030968
GeneOntologyBiologicalProcess	regulation of endoplasmic reticulum unfolded protein response	NCK1 BFAR NCK2	1.67e-04	34	65	3	GO:1900101
GeneOntologyBiologicalProcess	negative regulation of intracellular signal transduction	EPHB2 MAGI2 NLRP12 KANK1 PTPRJ CNKSR3 NCK1 BFAR NCK2 FBXW7	1.79e-04	795	65	10	GO:1902532
GeneOntologyBiologicalProcess	Fc receptor mediated stimulatory signaling pathway	PTPRJ CD226 HCK	1.82e-04	35	65	3	GO:0002431
GeneOntologyBiologicalProcess	regulation of protein phosphorylation	EPHB2 IL24 NLRP12 IL22RA2 PTPRJ CNKSR3 NCK1 EIF2AK3 LEPR IL6ST NCK2 FBXW7	1.92e-04	1133	65	12	GO:0001932
GeneOntologyBiologicalProcess	positive regulation of lymphocyte proliferation	EPHB2 CD1D NCK1 IL6ST NCK2	1.99e-04	170	65	5	GO:0050671
GeneOntologyBiologicalProcess	positive regulation of Fc receptor mediated stimulatory signaling pathway	PTPRJ CD226	2.03e-04	7	65	2	GO:0060369
GeneOntologyBiologicalProcess	regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway	NCK1 EIF2AK3 NCK2	2.15e-04	37	65	3	GO:1902235
GeneOntologyBiologicalProcess	positive regulation of mononuclear cell proliferation	EPHB2 CD1D NCK1 IL6ST NCK2	2.15e-04	173	65	5	GO:0032946
GeneOntologyBiologicalProcess	regulation of response to endoplasmic reticulum stress	NCK1 BFAR EIF2AK3 NCK2	2.40e-04	96	65	4	GO:1905897
GeneOntologyBiologicalProcess	translational elongation	GCN1 EEF1A1 EEF1A1P5 EEF1A2	2.50e-04	97	65	4	GO:0006414
GeneOntologyBiologicalProcess	negative regulation of PERK-mediated unfolded protein response	NCK1 NCK2	2.70e-04	8	65	2	GO:1903898
GeneOntologyBiologicalProcess	regulation of chaperone-mediated autophagy	EEF1A1 EEF1A2	2.70e-04	8	65	2	GO:1904714
GeneOntologyBiologicalProcess	positive regulation of translation in response to stress	NCK1 NCK2	2.70e-04	8	65	2	GO:0032056
GeneOntologyBiologicalProcess	signal complex assembly	NCK1 NCK2	2.70e-04	8	65	2	GO:0007172
GeneOntologyBiologicalProcess	cellular response to unfolded protein	NCK1 BFAR EIF2AK3 NCK2	2.81e-04	100	65	4	GO:0034620
GeneOntologyBiologicalProcess	regulation of cellular response to insulin stimulus	KANK1 PTPRJ NCK1 KBTBD2	2.92e-04	101	65	4	GO:1900076
GeneOntologyBiologicalProcess	positive regulation of leukocyte proliferation	EPHB2 CD1D NCK1 IL6ST NCK2	3.40e-04	191	65	5	GO:0070665
GeneOntologyBiologicalProcess	positive regulation of leukocyte activation	EPHB2 RIF1 CD1D CD226 NCK1 IL6ST NCK2	3.63e-04	423	65	7	GO:0002696
GeneOntologyBiologicalProcess	positive regulation of response to endoplasmic reticulum stress	NCK1 EIF2AK3 NCK2	3.86e-04	45	65	3	GO:1905898
GeneOntologyBiologicalProcess	cellular response to topologically incorrect protein	NCK1 BFAR EIF2AK3 NCK2	4.94e-04	116	65	4	GO:0035967
GeneOntologyBiologicalProcess	negative regulation of response to endoplasmic reticulum stress	NCK1 BFAR NCK2	4.96e-04	49	65	3	GO:1903573
GeneOntologyBiologicalProcess	regulation of lipid kinase activity	EEF1A1 EEF1A2	5.28e-04	11	65	2	GO:0043550
GeneOntologyBiologicalProcess	postsynaptic membrane assembly	EPHB2 MAGI2	5.28e-04	11	65	2	GO:0097104
GeneOntologyBiologicalProcess	positive regulation of T cell proliferation	CD1D NCK1 IL6ST NCK2	6.54e-04	125	65	4	GO:0042102
GeneOntologyBiologicalProcess	ephrin receptor signaling pathway	EPHB2 NCK1 NCK2	6.61e-04	54	65	3	GO:0048013
GeneOntologyBiologicalProcess	negative regulation of insulin receptor signaling pathway	KANK1 PTPRJ NCK1	6.61e-04	54	65	3	GO:0046627
GeneOntologyBiologicalProcess	regulation of PERK-mediated unfolded protein response	NCK1 NCK2	7.46e-04	13	65	2	GO:1903897
GeneOntologyBiologicalProcess	positive regulation of actin filament polymerization	NCK1 HCK NCK2	8.56e-04	59	65	3	GO:0030838
GeneOntologyBiologicalProcess	negative regulation of cellular response to insulin stimulus	KANK1 PTPRJ NCK1	8.56e-04	59	65	3	GO:1900077
GeneOntologyBiologicalProcess	regulation of Fc receptor mediated stimulatory signaling pathway	PTPRJ CD226	8.68e-04	14	65	2	GO:0060368
GeneOntologyBiologicalProcess	peptidyl-amino acid modification	EPHB2 IL24 IL22RA2 PTPRJ CNKSR3 NCK1 EIF2AK3 HCK IL6ST FBXW7	9.02e-04	976	65	10	GO:0018193
GeneOntologyBiologicalProcess	positive regulation of dephosphorylation	MAGI2 NCK1 NCK2	9.89e-04	62	65	3	GO:0035306
GeneOntologyBiologicalProcess	peptidyl-serine dephosphorylation	NCK1 NCK2	1.00e-03	15	65	2	GO:0070262
GeneOntologyBiologicalProcess	SREBP signaling pathway	EIF2AK3 FBXW7	1.14e-03	16	65	2	GO:0032933
GeneOntologyBiologicalProcess	negative regulation of protein phosphorylation	EPHB2 NLRP12 PTPRJ CNKSR3 NCK1 NCK2	1.16e-03	375	65	6	GO:0001933
GeneOntologyBiologicalProcess	regulation of adaptive immune response	EPHB2 RIF1 CD1D CD226 IL6ST	1.19e-03	252	65	5	GO:0002819
GeneOntologyBiologicalProcess	response to unfolded protein	NCK1 BFAR EIF2AK3 NCK2	1.23e-03	148	65	4	GO:0006986
GeneOntologyBiologicalProcess	chaperone-mediated autophagy	EEF1A1 EEF1A2	1.29e-03	17	65	2	GO:0061684
GeneOntologyBiologicalProcess	cellular response to sterol depletion	EIF2AK3 FBXW7	1.29e-03	17	65	2	GO:0071501
GeneOntologyBiologicalProcess	positive regulation of lymphocyte activation	EPHB2 RIF1 CD1D NCK1 IL6ST NCK2	1.33e-03	385	65	6	GO:0051251
GeneOntologyBiologicalProcess	regulation of actin filament polymerization	KANK1 NCK1 HCK NCK2	1.49e-03	156	65	4	GO:0030833
GeneOntologyBiologicalProcess	positive regulation of adaptive immune response	RIF1 CD1D CD226 IL6ST	1.60e-03	159	65	4	GO:0002821
GeneOntologyBiologicalProcess	positive regulation of immune system process	EPHB2 RIF1 CD1D PTPRJ SLC15A2 CD226 NCK1 HCK IL6ST GPR151 NCK2	1.61e-03	1242	65	11	GO:0002684
GeneOntologyBiologicalProcess	response to sterol depletion	EIF2AK3 FBXW7	1.62e-03	19	65	2	GO:0006991
GeneOntologyBiologicalProcess	negative regulation of phosphorylation	EPHB2 NLRP12 PTPRJ CNKSR3 NCK1 NCK2	1.63e-03	401	65	6	GO:0042326
GeneOntologyBiologicalProcess	regulation of peptidyl-tyrosine phosphorylation	IL24 IL22RA2 PTPRJ IL6ST FBXW7	1.67e-03	272	65	5	GO:0050730
GeneOntologyBiologicalProcess	positive regulation of phosphate metabolic process	IL24 MAGI2 PTPRJ NCK1 LEPR IL6ST NCK2 EEF1A2 FBXW7	1.67e-03	879	65	9	GO:0045937
GeneOntologyBiologicalProcess	positive regulation of phosphorus metabolic process	IL24 MAGI2 PTPRJ NCK1 LEPR IL6ST NCK2 EEF1A2 FBXW7	1.67e-03	879	65	9	GO:0010562
GeneOntologyCellularComponent	eukaryotic translation elongation factor 1 complex	EEF1A1 EEF1A2	5.69e-05	4	65	2	GO:0005853
Domain	HRD	UBN1 UBN2	1.12e-05	2	63	2	IPR014840
Domain	UBN_middle_dom	UBN1 UBN2	1.12e-05	2	63	2	IPR026947
Domain	NCK	NCK1 NCK2	1.12e-05	2	63	2	IPR017304
Domain	UBN_AB	UBN1 UBN2	1.12e-05	2	63	2	PF14075
Domain	HUN	UBN1 UBN2	1.12e-05	2	63	2	PF08729
Domain	Transl_elong_EF1A_euk/arc	EEF1A1 EEF1A2	1.12e-05	2	63	2	IPR004539
Domain	FN3	EPHB2 IL22RA2 PTPRJ LEPR IL6ST MYBPC3	5.56e-05	199	63	6	PS50853
Domain	IgC2-like_lig-bd	LEPR IL6ST	6.69e-05	4	63	2	IPR010457
Domain	Lep_receptor_Ig	LEPR IL6ST	6.69e-05	4	63	2	PF06328
Domain	-	EPHB2 CD1D IL22RA2 PTPRJ CD226 IGSF1 LEPR IL6ST IGSF3 MYBPC3	6.93e-05	663	63	10	2.60.40.10
Domain	FN3_dom	EPHB2 IL22RA2 PTPRJ LEPR IL6ST MYBPC3	7.30e-05	209	63	6	IPR003961
Domain	Ig-like_fold	EPHB2 CD1D IL22RA2 PTPRJ CD226 IGSF1 LEPR IL6ST IGSF3 MYBPC3	1.17e-04	706	63	10	IPR013783
Domain	Hematopoietin_rcpt_Gp130_CS	LEPR IL6ST	2.33e-04	7	63	2	IPR003529
Domain	Transl_elong_EFTu/EF1A_C	EEF1A1 EEF1A2	3.09e-04	8	63	2	IPR004160
Domain	HEMATOPO_REC_L_F2	LEPR IL6ST	3.09e-04	8	63	2	PS01353
Domain	GTP_EFTU_D3	EEF1A1 EEF1A2	3.09e-04	8	63	2	PF03143
Domain	G_TR_CS	EEF1A1 EEF1A2	3.97e-04	9	63	2	IPR031157
Domain	FN3	EPHB2 PTPRJ LEPR IL6ST MYBPC3	3.99e-04	185	63	5	SM00060
Domain	BTB-kelch_protein	KLHL7 KLHL13 KBTBD2	4.10e-04	43	63	3	IPR017096
Domain	-	EPHB2 CNKSR3 SPDEF BFAR	4.51e-04	106	63	4	1.10.150.50
Domain	Transl_elong_EF1A/Init_IF2_C	EEF1A1 EEF1A2	4.95e-04	10	63	2	IPR009001
Domain	SAM/pointed	EPHB2 CNKSR3 SPDEF BFAR	6.55e-04	117	63	4	IPR013761
Domain	G_TR_1	EEF1A1 EEF1A2	8.53e-04	13	63	2	PS00301
Domain	Kelch	KLHL7 KLHL13 KBTBD2	9.89e-04	58	63	3	SM00612
Domain	BACK	KLHL7 KLHL13 KBTBD2	1.09e-03	60	63	3	SM00875
Domain	BACK	KLHL7 KLHL13 KBTBD2	1.15e-03	61	63	3	PF07707
Domain	BACK	KLHL7 KLHL13 KBTBD2	1.15e-03	61	63	3	IPR011705
Domain	SAM_1	EPHB2 CNKSR3 BFAR	1.57e-03	68	63	3	PF00536
Domain	UIM	ANKRD13B ANKIB1	1.65e-03	18	63	2	PF02809
Domain	EFTu-like_2	EEF1A1 EEF1A2	1.65e-03	18	63	2	IPR004161
Domain	GTP_EFTU_D2	EEF1A1 EEF1A2	1.65e-03	18	63	2	PF03144
Domain	G_TR_2	EEF1A1 EEF1A2	1.65e-03	18	63	2	PS51722
Domain	Kelch_1	KLHL7 KLHL13 KBTBD2	1.70e-03	70	63	3	PF01344
Domain	Kelch_1	KLHL7 KLHL13 KBTBD2	1.70e-03	70	63	3	IPR006652
Domain	TF_GTP-bd_dom	EEF1A1 EEF1A2	1.85e-03	19	63	2	IPR000795
Domain	fn3	EPHB2 PTPRJ IL6ST MYBPC3	2.18e-03	162	63	4	PF00041
Domain	UIM	ANKRD13B ANKIB1	2.26e-03	21	63	2	SM00726
Domain	-	STARD8 AHSA1	2.71e-03	23	63	2	3.30.530.20
Domain	START-like_dom	STARD8 AHSA1	2.71e-03	23	63	2	IPR023393
Domain	UIM	ANKRD13B ANKIB1	2.95e-03	24	63	2	PS50330
Domain	UIM_dom	ANKRD13B ANKIB1	3.20e-03	25	63	2	IPR003903
Domain	SAM	EPHB2 CNKSR3 BFAR	3.27e-03	88	63	3	SM00454
Domain	Transl_B-barrel	EEF1A1 EEF1A2	3.72e-03	27	63	2	IPR009000
Domain	SAM_DOMAIN	EPHB2 CNKSR3 BFAR	4.06e-03	95	63	3	PS50105
Domain	SAM	EPHB2 CNKSR3 BFAR	4.30e-03	97	63	3	IPR001660
Domain	SH2	NCK1 HCK NCK2	4.82e-03	101	63	3	PF00017
Domain	SH2	NCK1 HCK NCK2	6.11e-03	110	63	3	SM00252
Domain	IG_LIKE	CD1D CD226 IGSF1 LEPR IGSF3 MYBPC3	6.14e-03	491	63	6	PS50835
Domain	SH2	NCK1 HCK NCK2	6.26e-03	111	63	3	PS50001
Domain	SH2	NCK1 HCK NCK2	6.42e-03	112	63	3	IPR000980
Domain	-	NCK1 HCK NCK2	6.42e-03	112	63	3	3.30.505.10
Pathway	REACTOME_NEPHRIN_FAMILY_INTERACTIONS	MAGI2 NCK1 NCK2	6.25e-05	23	48	3	M913
Pathway	PID_EPHRINB_REV_PATHWAY	EPHB2 HCK NCK2	1.41e-04	30	48	3	M257
Pubmed	Nck-1 antagonizes the endoplasmic reticulum stress-induced inhibition of translation.	NCK1 EIF2AK3 NCK2	6.53e-09	3	66	3	14676213
Pubmed	Independent SH2-binding sites mediate interaction of Dok-related protein with RasGTPase-activating protein and Nck.	NCK1 HCK NCK2	5.44e-07	9	66	3	10428862
Pubmed	Assignment of human elongation factor 1alpha genes: EEF1A maps to chromosome 6q14 and EEF1A2 to 20q13.3.	EEF1A1 EEF1A1P5 EEF1A2	2.92e-06	15	66	3	8812466
Pubmed	New insights on the interaction between the isoforms 1 and 2 of human translation elongation factor 1A.	EEF1A1 EEF1A2	3.55e-06	2	66	2	26212729
Pubmed	Fine tuning of the threshold of T cell selection by the Nck adapters.	NCK1 NCK2	3.55e-06	2	66	2	21078909
Pubmed	Non-compensating roles between Nckalpha and Nckbeta in PDGF-BB signaling to promote human dermal fibroblast migration.	NCK1 NCK2	3.55e-06	2	66	2	19242519
Pubmed	The expression levels of the translational factors eEF1A 1/2 correlate with cell growth but not apoptosis in hepatocellular carcinoma cell lines with different differentiation grade.	EEF1A1 EEF1A2	3.55e-06	2	66	2	17825975
Pubmed	Nck1 deficiency improves pancreatic β cell survival to diabetes-relevant stresses by modulating PERK activation and signaling.	NCK1 EIF2AK3	3.55e-06	2	66	2	26434994
Pubmed	Dissecting the expression of EEF1A1/2 genes in human prostate cancer cells: the potential of EEF1A2 as a hallmark for prostate transformation and progression.	EEF1A1 EEF1A2	3.55e-06	2	66	2	22095224
Pubmed	eEF1A demonstrates paralog specific effects on HIV-1 reverse transcription efficiency.	EEF1A1 EEF1A2	3.55e-06	2	66	2	30782564
Pubmed	[A uNick protein].	NCK1 NCK2	3.55e-06	2	66	2	21880263
Pubmed	Nck adaptor proteins modulate differentiation and effector function of T cells.	NCK1 NCK2	3.55e-06	2	66	2	25995205
Pubmed	ER stress increases expression of intracellular calcium channel RyR1 to modify Ca2+ homeostasis in pancreatic beta cells.	LEPR RYR1	3.55e-06	2	66	2	37468098
Pubmed	Nck adaptor proteins control the organization of neuronal circuits important for walking.	NCK1 NCK2	3.55e-06	2	66	2	18093944
Pubmed	Activation of invariant natural killer T cells by lipid excess promotes tissue inflammation, insulin resistance, and hepatic steatosis in obese mice.	CD1D LEPR	3.55e-06	2	66	2	22493234
Pubmed	Nck adaptor proteins link Tks5 to invadopodia actin regulation and ECM degradation.	NCK1 NCK2	3.55e-06	2	66	2	19596797
Pubmed	Nck influences preosteoblastic/osteoblastic migration and bone mass.	NCK1 NCK2	3.55e-06	2	66	2	26621720
Pubmed	Understanding functions of eEF1 translation elongation factors beyond translation. A proteomic approach.	EEF1A1 EEF1A2	3.55e-06	2	66	2	38220433
Pubmed	Structural models of human eEF1A1 and eEF1A2 reveal two distinct surface clusters of sequence variation and potential differences in phosphorylation.	EEF1A1 EEF1A2	3.55e-06	2	66	2	19636410
Pubmed	UBN1/2 of HIRA complex is responsible for recognition and deposition of H3.3 at cis-regulatory elements of genes in mouse ES cells.	UBN1 UBN2	3.55e-06	2	66	2	30285846
Pubmed	Nck adaptors are positive regulators of the size and sensitivity of the T-cell repertoire.	NCK1 NCK2	3.55e-06	2	66	2	20709959
Pubmed	Analysis of the Expression and Subcellular Distribution of eEF1A1 and eEF1A2 mRNAs during Neurodevelopment.	EEF1A1 EEF1A2	3.55e-06	2	66	2	35741005
Pubmed	Endothelial NCK2 promotes atherosclerosis progression in male but not female Nck1-null atheroprone mice.	NCK1 NCK2	3.55e-06	2	66	2	36035930
Pubmed	Signaling through a novel domain of gp130 mediates cell proliferation and activation of Hck and Erk kinases.	HCK IL6ST	3.55e-06	2	66	2	11689697
Pubmed	The role of translation elongation factor eEF1 subunits in neurodevelopmental disorders.	EEF1A1 EEF1A2	3.55e-06	2	66	2	30370994
Pubmed	Distinct Requirements for Adaptor Proteins NCK1 and NCK2 in Mammary Gland Development.	NCK1 NCK2	3.55e-06	2	66	2	37479911
Pubmed	Cloning of human and mouse brain cDNAs coding for S1, the second member of the mammalian elongation factor-1 alpha gene family: analysis of a possible evolutionary pathway.	EEF1A1 EEF1A2	3.55e-06	2	66	2	7945283
Pubmed	The phosphotyrosine peptide binding specificity of Nck1 and Nck2 Src homology 2 domains.	NCK1 NCK2	3.55e-06	2	66	2	16636066
Pubmed	Dimethylation of eEF1A at Lysine 55 Plays a Key Role in the Regulation of eEF1A2 on Malignant Cell Functions of Acute Myeloid Leukemia.	EEF1A1 EEF1A2	3.55e-06	2	66	2	32347192
Pubmed	Nucleotide binding domain and leucine-rich repeat pyrin domain-containing protein 12: characterization of its binding to hematopoietic cell kinase.	NLRP12 HCK	1.06e-05	3	66	2	32226298
Pubmed	Cooperative Interaction of Nck and Lck Orchestrates Optimal TCR Signaling.	NCK1 NCK2	1.06e-05	3	66	2	33917227
Pubmed	Nck adaptors, besides promoting N-WASP mediated actin-nucleation activity at pedestals, influence the cellular levels of enteropathogenic Escherichia coli Tir effector.	NCK1 NCK2	1.06e-05	3	66	2	25482634
Pubmed	Interaction of elongation factor 1-alpha with leucine-rich repeat kinase 2 impairs kinase activity and microtubule bundling in vitro.	EEF1A1 EEF1A2	1.06e-05	3	66	2	19559761
Pubmed	A Study of Interleukin-2 Production and Nck Adaptor Molecule Gene Expression in Systemic Lupus Erythematosus Patients.	NCK1 NCK2	1.06e-05	3	66	2	29911835
Pubmed	Nephrin Suppresses Hippo Signaling through the Adaptor Proteins Nck and WTIP.	NCK1 NCK2	1.06e-05	3	66	2	27033705
Pubmed	Requirement of Nck adaptors for actin dynamics and cell migration stimulated by platelet-derived growth factor B.	NCK1 NCK2	1.06e-05	3	66	2	16769879
Pubmed	Selective role of Nck1 in atherogenic inflammation and plaque formation.	NCK1 NCK2	1.06e-05	3	66	2	32427580
Pubmed	Nck proteins maintain the adult glomerular filtration barrier.	NCK1 NCK2	1.06e-05	3	66	2	19443634
Pubmed	Identification and kinetic analysis of the interaction between Nck-2 and DOCK180.	NCK1 NCK2	1.06e-05	3	66	2	11240126
Pubmed	Nck beta interacts with tyrosine-phosphorylated disabled 1 and redistributes in Reelin-stimulated neurons.	NCK1 NCK2	1.06e-05	3	66	2	14517291
Pubmed	A meta-analysis of genome-wide association studies identifies ORM1 as a novel gene controlling thrombin generation potential.	PTPRJ MYBPC3	1.06e-05	3	66	2	24357727
Pubmed	The nucleocapsid protein of severe acute respiratory syndrome coronavirus inhibits cell cytokinesis and proliferation by interacting with translation elongation factor 1alpha.	EEF1A1 EEF1A2	1.06e-05	3	66	2	18448518
Pubmed	Nck-2 interacts with focal adhesion kinase and modulates cell motility.	NCK1 NCK2	1.06e-05	3	66	2	11950595
Pubmed	Nck adapter proteins promote podosome biogenesis facilitating extracellular matrix degradation and cancer invasion.	NCK1 NCK2	1.06e-05	3	66	2	31638742
Pubmed	Src homology domain 2 adaptors affect adherence of Salmonella enterica serovar Typhimurium to non-phagocytic cells.	NCK1 NCK2	1.06e-05	3	66	2	17906149
Pubmed	PERK in POMC neurons connects celastrol with metabolism.	EIF2AK3 LEPR	1.06e-05	3	66	2	34549728
Pubmed	Endogenous epitope tagging of eEF1A2 in mice reveals early embryonic expression of eEF1A2 and subcellular compartmentalisation of neuronal eEF1A1 and eEF1A2.	EEF1A1 EEF1A2	1.06e-05	3	66	2	37429391
Pubmed	Glycoprotein 130 receptor signaling mediates α-cell dysfunction in a rodent model of type 2 diabetes.	LEPR IL6ST	1.06e-05	3	66	2	24812426
Pubmed	The cytoskeletal scaffold Shank3 is recruited to pathogen-induced actin rearrangements.	NCK1 NCK2	1.06e-05	3	66	2	19371741
Pubmed	The SH2 and SH3 domain-containing Nck protein is oncogenic and a common target for phosphorylation by different surface receptors.	NCK1 NCK2	2.12e-05	4	66	2	1333047
Pubmed	Characterization of elongation factor-1A (eEF1A-1) and eEF1A-2/S1 protein expression in normal and wasted mice.	EEF1A1 EEF1A2	2.12e-05	4	66	2	11294870
Pubmed	Juxtamembrane tyrosine residues couple the Eph family receptor EphB2/Nuk to specific SH2 domain proteins in neuronal cells.	EPHB2 NCK1	2.12e-05	4	66	2	9233798
Pubmed	The ubiquitin ligase FBXW7 modulates leukemia-initiating cell activity by regulating MYC stability.	EEF1A1 FBXW7	2.12e-05	4	66	2	23791182
Pubmed	Nck adapters are involved in the formation of dorsal ruffles, cell migration, and Rho signaling downstream of the platelet-derived growth factor beta receptor.	NCK1 NCK2	2.12e-05	4	66	2	18765673
Pubmed	Identification of regulators of chaperone-mediated autophagy.	EEF1A1 EEF1A2	2.12e-05	4	66	2	20797626
Pubmed	Recruitment of Nck by CD3 epsilon reveals a ligand-induced conformational change essential for T cell receptor signaling and synapse formation.	NCK1 NCK2	2.12e-05	4	66	2	12110186
Pubmed	PERK-dependent regulation of ceramide synthase 6 and thioredoxin play a key role in mda-7/IL-24-induced killing of primary human glioblastoma multiforme cells.	IL24 EIF2AK3	2.12e-05	4	66	2	20103619
Pubmed	Reciprocal regulation of SH3 and SH2 domain binding via tyrosine phosphorylation of a common site in CD3epsilon.	NCK1 NCK2	2.12e-05	4	66	2	17617578
Pubmed	Nck adaptor proteins link nephrin to the actin cytoskeleton of kidney podocytes.	NCK1 NCK2	2.12e-05	4	66	2	16525419
Pubmed	Nck-mediated recruitment of BCAP to the BCR regulates the PI(3)K-Akt pathway in B cells.	NCK1 NCK2	2.12e-05	4	66	2	23913047
Pubmed	The Nucleo-cytoplasmic actin-binding protein CapG lacks a nuclear export sequence present in structurally related proteins.	NCK1 NCK2	2.12e-05	4	66	2	12637565
Pubmed	Human UBN1 is an ortholog of yeast Hpc2p and has an essential role in the HIRA/ASF1a chromatin-remodeling pathway in senescent cells.	UBN1 UBN2	2.12e-05	4	66	2	19029251
Pubmed	NCK is critical for the development of deleted in colorectal cancer (DCC) sensitive spinal circuits.	NCK1 NCK2	2.12e-05	4	66	2	25913325
Pubmed	Immuno-characterization of the switch of peptide elongation factors eEF1A-1/EF-1alpha and eEF1A-2/S1 in the central nervous system during mouse development.	EEF1A1 EEF1A2	2.12e-05	4	66	2	15013623
Pubmed	Improved two-dimensional reversed phase-reversed phase LC-MS/MS approach for identification of peptide-protein interactions.	NCK1 NCK2	2.12e-05	4	66	2	22074159
Pubmed	A quantitative protein interaction network for the ErbB receptors using protein microarrays.	DOK6 NCK1 HCK NCK2	2.67e-05	90	66	4	16273093
Pubmed	Identification of Nck family genes, chromosomal localization, expression, and signaling specificity.	NCK1 NCK2	3.53e-05	5	66	2	9737977
Pubmed	Hypothalamic Amylin Acts in Concert with Leptin to Regulate Food Intake.	LEPR EEF1A1	3.53e-05	5	66	2	26655697
Pubmed	The human Y-encoded testis-specific protein interacts functionally with eukaryotic translation elongation factor eEF1A, a putative oncoprotein.	EEF1A1 EEF1A2	3.53e-05	5	66	2	18649364
Pubmed	The murine Nck SH2/SH3 adaptors are important for the development of mesoderm-derived embryonic structures and for regulating the cellular actin network.	NCK1 NCK2	3.53e-05	5	66	2	12808099
Pubmed	Nt mutation causing laterality defects associated with deletion of rotatin.	DOK6 CD226	3.53e-05	5	66	2	17551791
Pubmed	Phosphatidylinositol 4,5-biphosphate (PIP2)-induced vesicle movement depends on N-WASP and involves Nck, WIP, and Grb2.	NCK1 NCK2	3.53e-05	5	66	2	12147689
Pubmed	IL-22R Ligands IL-20, IL-22, and IL-24 Promote Wound Healing in Diabetic db/db Mice.	IL24 LEPR	3.53e-05	5	66	2	28125663
Pubmed	A hotspot mutation targeting the R-RAS2 GTPase acts as a potent oncogenic driver in a wide spectrum of tumors.	NCK1 NCK2	3.53e-05	5	66	2	35294890
Pubmed	Nck and Cdc42 co-operate to recruit N-WASP to promote FcγR-mediated phagocytosis.	NCK1 NCK2	3.53e-05	5	66	2	22454526
Pubmed	Insulin action and resistance are dependent on a GSK3β-FBXW7-ERRα transcriptional axis.	LEPR FBXW7	3.53e-05	5	66	2	35440636
Pubmed	Identification of a group of cellular cofactors that stimulate the binding of RNA polymerase II and TRP-185 to human immunodeficiency virus 1 TAR RNA.	EEF1A1 EEF1A2	3.53e-05	5	66	2	8626763
Pubmed	Proteasomal degradation of Nck1 but not Nck2 regulates RhoA activation and actin dynamics.	NCK1 NCK2	5.29e-05	6	66	2	24287595
Pubmed	Nck in a complex containing the catalytic subunit of protein phosphatase 1 regulates eukaryotic initiation factor 2alpha signaling and cell survival to endoplasmic reticulum stress.	NCK1 NCK2	5.29e-05	6	66	2	16835242
Pubmed	Delta proteins and MAGI proteins: an interaction of Notch ligands with intracellular scaffolding molecules and its significance for zebrafish development.	MAGI2 CNKSR3	5.29e-05	6	66	2	15509766
Pubmed	CXCL12-Producing Vascular Endothelial Niches Control Acute T Cell Leukemia Maintenance.	LEPR EEF1A1	5.29e-05	6	66	2	26058075
Pubmed	Ephrin-B3 reverse signaling through Grb4 and cytoskeletal regulators mediates axon pruning.	EPHB2 NCK2	5.29e-05	6	66	2	19182796
Pubmed	HIV-1 Tat activates neuronal ryanodine receptors with rapid induction of the unfolded protein response and mitochondrial hyperpolarization.	EIF2AK3 RYR1	5.29e-05	6	66	2	19009018
Pubmed	High-efficiency expression/cloning of epidermal growth factor-receptor-binding proteins with Src homology 2 domains.	NCK1 NCK2	5.29e-05	6	66	2	1409582
Pubmed	Septins regulate actin organization and cell-cycle arrest through nuclear accumulation of NCK mediated by SOCS7.	NCK1 NCK2	5.29e-05	6	66	2	17803907
Pubmed	Mouse translation elongation factor eEF1A-2 interacts with Prdx-I to protect cells against apoptotic death induced by oxidative stress.	EEF1A1 EEF1A2	5.29e-05	6	66	2	16888816
Pubmed	Src-induced phosphorylation of caveolin-2 on tyrosine 19. Phospho-caveolin-2 (Tyr(P)19) is localized near focal adhesions, remains associated with lipid rafts/caveolae, but no longer forms a high molecular mass hetero-oligomer with caveolin-1.	NCK1 NCK2	5.29e-05	6	66	2	12091389
Pubmed	Sustained remission of type 2 diabetes in rodents by centrally administered fibroblast growth factor 4.	LEPR EEF1A1	5.29e-05	6	66	2	37167965
Pubmed	Requisite role for Nck adaptors in cardiovascular development, endothelial-to-mesenchymal transition, and directed cell migration.	NCK1 NCK2	5.29e-05	6	66	2	25691664
Pubmed	Oncogenic functions of protein kinase D2 and D3 in regulating multiple cancer-related pathways in breast cancer.	WDR19 EEF1A1 EEF1A1P5 EEF1A2	7.22e-05	116	66	4	30652415
Pubmed	Brain-derived neurotrophic factor promotes interaction of the Nck2 adaptor protein with the TrkB tyrosine kinase receptor.	NCK1 NCK2	7.40e-05	7	66	2	12074588
Pubmed	Molecular characterization of a testis-specific estrogen sulfotransferase and aberrant liver expression in obese and diabetogenic C57BL/KsJ-db/db mice.	HCK LEPR	7.40e-05	7	66	2	7750469
Pubmed	A function for cyclin D1 in DNA repair uncovered by protein interactome analyses in human cancers.	RIF1 AHSA1 GCN1 EEF1A1	9.65e-05	125	66	4	21654808
Pubmed	E-cadherin interactome complexity and robustness resolved by quantitative proteomics.	PTPRJ NCK1 AHSA1 GCN1 IL6ST NCK2 EEF1A1	9.78e-05	565	66	7	25468996
Pubmed	The Cdc42-associated kinase ACK1 is not autoinhibited but requires Src for activation.	NCK1 HCK	9.86e-05	8	66	2	21309750
Pubmed	AR-12 Inhibits Multiple Chaperones Concomitant With Stimulating Autophagosome Formation Collectively Preventing Virus Replication.	AHSA1 EIF2AK3	9.86e-05	8	66	2	27187154
Pubmed	An E3 ligase network engages GCN1 to promote the degradation of translation factors on stalled ribosomes.	GCN1 EEF1A1	9.86e-05	8	66	2	36638793
Pubmed	Targeting NCK-Mediated Endothelial Cell Front-Rear Polarity Inhibits Neovascularization.	NCK1 NCK2	9.86e-05	8	66	2	26659946
Pubmed	YB-1 is important for an early stage embryonic development: neural tube formation and cell proliferation.	EEF1A1 EEF1A2	9.86e-05	8	66	2	17082189
Pubmed	Grb4 and GIT1 transduce ephrinB reverse signals modulating spine morphogenesis and synapse formation.	EPHB2 NCK2	9.86e-05	8	66	2	17310244
Interaction	FER1L6 interactions	EEF1A1 EEF1A1P5 EEF1A2	1.06e-06	7	64	3	int:FER1L6
Interaction	LGALS7 interactions	PTPRJ DPYSL5 SLC12A7 VPS13B IGSF3 FBXW7	5.21e-06	139	64	6	int:LGALS7
Interaction	DLL1 interactions	MAGI2 CNKSR3 NCK1 FBXW7	6.29e-06	38	64	4	int:DLL1
Interaction	ADARB2 interactions	EEF1A1 EEF1A1P5 EEF1A2	2.01e-05	17	64	3	int:ADARB2
Interaction	DOCK5 interactions	WDR19 RIF1 RAB3GAP1 TRRAP VPS13B	2.73e-05	111	64	5	int:DOCK5
Interaction	SUMF2 interactions	SUMF2 ZFYVE9 PLD4 FBXW7	3.69e-05	59	64	4	int:SUMF2
Interaction	SNX20 interactions	ENOSF1 SPDEF VPS13B	4.51e-05	22	64	3	int:SNX20
GeneFamily	Fibronectin type III domain containing	EPHB2 PTPRJ IL6ST MYBPC3	7.22e-04	160	46	4	555
GeneFamily	Sterile alpha motif domain containing	EPHB2 CNKSR3 BFAR	1.45e-03	88	46	3	760
GeneFamily	SH2 domain containing	NCK1 HCK NCK2	2.16e-03	101	46	3	741
GeneFamily	ADAM metallopeptidase domain containing\|CD molecules	CD1D PTPRJ CD226 LEPR IL6ST	3.15e-03	394	46	5	471
GeneFamily	Basic leucine zipper proteins\|BTB domain containing	KLHL7 KLHL13 KBTBD2	4.79e-03	134	46	3	861
GeneFamily	Kelch like\|BTB domain containing	KLHL7 KLHL13	5.11e-03	42	46	2	617
GeneFamily	CD molecules\|I-set domain containing\|Immunoglobulin like domain containing\|Interleukin receptors\|TIR domain containing	IL22RA2 IL6ST	5.11e-03	42	46	2	602
Coexpression	GSE4142_PLASMA_CELL_VS_GC_BCELL_UP	ELOVL4 IL22RA2 NCK1 KBTBD2 EIF2AK3 FBXW7	1.04e-05	200	65	6	M6390
Coexpression	FARMER_BREAST_CANCER_BASAL_VS_LULMINAL	WDR19 RIF1 KLHL7 MTHFD2 SPDEF NCK1 IL6ST	1.72e-05	329	65	7	M5652
ToppCell	droplet-Lung-nan-3m-Myeloid-Nonclassical_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOK6 PTPRJ HCK RYR1 PLD4	3.22e-06	153	66	5	6dcab3d50ab50051955204dc4e4a64c1ca855bcd
ToppCell	droplet-Lung-nan-3m-Myeloid-non-classical_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOK6 PTPRJ HCK RYR1 PLD4	3.22e-06	153	66	5	f6ef14d949107c08cb3690e26ec91e194cb43518
ToppCell	3'_v3-GI_small-bowel-Lymphocytic_T_CD4-Tregs\|GI_small-bowel / Manually curated celltypes from each tissue	CDHR3 IGSF1 DNAH8 RYR1 NCK2	3.43e-06	155	66	5	d4ef25965a15eab7679478b9b661e1b4a92f1c59
ToppCell	saliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	FAM78A CDHR3 FUT9 DNAH8 PLD4	3.54e-06	156	66	5	a5930b455e5c8586c43c50106ab4d8a1e5e9e3d6
ToppCell	Control-Lymphocytic_B-B_cells\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PTPRJ EIF2AK3 HCK PLD4 EEF1A2	4.94e-06	167	66	5	a15a70d3837b31cc83a2a9e3f1bbfd77a95f2312
ToppCell	droplet-Kidney-nan-24m-Myeloid-nan\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NLRP12 MTHFD2 HCK RYR1 PLD4	4.94e-06	167	66	5	2ee1660be117e20f24557522345572d11cbee813
ToppCell	Control-Lymphocytic_B\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PTPRJ EIF2AK3 HCK PLD4 EEF1A2	4.94e-06	167	66	5	956da82394fd6a9f45fc2031796f12cc889542cd
ToppCell	Control-Lymphocytic_B-B_cells-B-cells\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PTPRJ EIF2AK3 HCK PLD4 EEF1A2	4.94e-06	167	66	5	69ed8a4a507190a1a66c4baf1f3e9be21ada39d8
ToppCell	tumor_Lymph_Node_/_Brain-Myeloid_cells-CD1c+_DCs\|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass	CD1D IL22RA2 STARD8 HCK PLD4	5.39e-06	170	66	5	403b6b749d70d845838dcda7daf99971b50792a2
ToppCell	facs-Spleen-nan-3m-Lymphocytic-Cd3e_T_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAM78A CD226 SLC12A7 IL6ST EEF1A1	7.30e-06	181	66	5	be7c7db6b99603759593e6f79cdcaa4bbf234cb7
ToppCell	Smart-seq2-lymph_node_(Smart-seq2)-lymphocytic-T_lymphocytic-effector_CD4-positive,_alpha-beta_T_cell\|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	KANK1 CD226 IL6ST EEF1A1 EEF1A1P5	8.55e-06	187	66	5	e61c1755531469dd3850c9740474b5ad4e0499c1
ToppCell	Children_(3_yrs)-Immune-monocyte-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	NLRP12 CD1D PTPRJ HCK PLD4	9.97e-06	193	66	5	58e1930a1d80ad3729ab9604ac8ebf7308232a3d
ToppCell	Bronchial-NucSeq\|Bronchial / Cell types per location group and 10X technology with lineage, and cell group designations	MAGI2 KANK1 PTPRJ VPS13B FBXW7	1.07e-05	196	66	5	ab53c742866945545a92e2e61850d63c80d9a2a6
ToppCell	Control-B_naive-8\|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)	PTPRJ HCK NCK2 EEF1A1 PLD4	1.07e-05	196	66	5	54074da84000e4749ade8acc542f05a275bf829f
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-DC-cDC2-Z\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CD1D IL22RA2 CD226 HCK PLD4	1.10e-05	197	66	5	4f7c10a636646dfc82a84026c1b5a36603367abe
ToppCell	Control-B_naive-8\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	PTPRJ HCK NCK2 EEF1A1 PLD4	1.10e-05	197	66	5	925bf0d38e4ce279fa45f455546ebd199282c0df
ToppCell	LPS_only-Hematopoietic_Myeloid-Dendritic_cells-pDC\|LPS_only / Treatment groups by lineage, cell group, cell type	KLHL7 MTHFD2 KLHL13 DPYSL5 PLD4	1.13e-05	198	66	5	d205dfcfe1f20e1e21bf84759e723d9e6e610a5c
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW23-Myeloid-Microglia\|GW23 / Sample Type, Dataset, Time_group, and Cell type.	FAM78A HCK IL6ST RYR1 PLD4	1.16e-05	199	66	5	4ddfbcaa8054b69b3398d8c0d5fab8ae94805cb9
ToppCell	Sepsis-ICU-NoSEP-Lymphocyte-T/NK-CD4+_Tem\|ICU-NoSEP / Disease, condition lineage and cell class	ELOVL4 ANKRD13B DOK6 NCK2 EEF1A1	1.16e-05	199	66	5	3382dfd446e362c94d8d92a3d78c3d0022cbe69c
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW23-Myeloid\|GW23 / Sample Type, Dataset, Time_group, and Cell type.	FAM78A HCK IL6ST RYR1 PLD4	1.16e-05	199	66	5	3ba48a4715d5e9387650aa97e0c5d7f7897bf380
ToppCell	343B-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_4\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	IL24 ELOVL4 FAM78A SLC12A7	6.05e-05	143	66	4	ce045ec7c311a1797ae562bec114f9e90604d063
ToppCell	droplet-Lung-nan-3m-Myeloid-intermediate_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZFYVE9 PTPRJ HCK RYR1	6.05e-05	143	66	4	4d11d53330a9197275a8851e1bbf55a113715a09
ToppCell	droplet-Lung-nan-3m-Myeloid-Intermediate_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZFYVE9 PTPRJ HCK RYR1	6.05e-05	143	66	4	8b9f4d87d5faac7752c83e1992491fc5550600f8
ToppCell	Smart-seq2-lymph_node_(Smart-seq2)-lymphocytic-T_lymphocytic-T_cell\|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	CD226 IL6ST EEF1A1 EEF1A1P5	7.28e-05	150	66	4	c922dbb4c9c12ccf08bd5f6168b20606c605d052
ToppCell	droplet-Lung-3m-Hematologic-myeloid-intermediate_monocyte\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PTPRJ HCK RYR1 PLD4	7.28e-05	150	66	4	b37f538ca5f976b509efe35dc81115b72b227084
ToppCell	droplet-Lung-3m-Hematologic-myeloid-intermediate_monocyte-intermediate_monocyte_l4\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PTPRJ HCK RYR1 PLD4	7.28e-05	150	66	4	2c7518918c40e1bf679a2d4e83b472ee6f2f9df8
ToppCell	facs-Diaphragm-Limb_Muscle-24m-Myeloid-macrophage\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL22RA2 STARD8 HCK PLD4	7.86e-05	153	66	4	4b999892fb797e9f0d391630094f466463299d57
ToppCell	facs-Diaphragm-Limb_Muscle-24m-Myeloid-nan\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL22RA2 STARD8 HCK PLD4	7.86e-05	153	66	4	e426db29e4ba83e7930dc88c74fc975b177c9540
ToppCell	facs-Diaphragm-Limb_Muscle-24m-Myeloid\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL22RA2 STARD8 HCK PLD4	7.86e-05	153	66	4	668eacd76aad6054bd7d57e3af0b122c2443465f
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Myeloid-Dendritic-conventional_dendritic_cell-DC_c1-CLEC9A\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	ANKRD13B DOK6 KAT14 PLD4	8.27e-05	155	66	4	d76a0f99ec35560d18820f9c92b69364ef2250e3
ToppCell	metastatic_Brain-Myeloid_cells-CD1c+_DCs\|metastatic_Brain / Location, Cell class and cell subclass	CD1D IL22RA2 HCK PLD4	9.13e-05	159	66	4	35a63ca521635389a1edc7c81157793b8ad24d38
ToppCell	3'-Distal_airway-Immune_Myeloid-Myeloid_monocytic-non-classical_monocyte-Non-classical_monocytes-Non-classical_monocytes_L.1.2.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PTPRJ KAT14 HCK PLD4	9.35e-05	160	66	4	709ce00699ca05346287868ea55a1affae0859a8
ToppCell	droplet-Heart-4Chambers\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KANK1 IGSF3 EEF1A2 MYBPC3	9.81e-05	162	66	4	5625ec6dae204d5537883f05ea546970628d10bb
ToppCell	facs-MAT-Fat-3m-Myeloid-myeloid_cell\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STARD8 PTPRJ HCK PLD4	1.00e-04	163	66	4	5fc836444bc156c8248abee001b0ecbe43f980c9
ToppCell	facs-Lung-3m-Hematologic-myeloid-non-classical_monocyte\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PTPRJ HCK RYR1 PLD4	1.00e-04	163	66	4	bbbc3f0ce2616d07136f69ce682ba1d3790711d9
ToppCell	droplet-Lung-3m-Hematologic-myeloid-non-classical_monocyte\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PTPRJ HCK RYR1 PLD4	1.00e-04	163	66	4	f6c8db5963ee1f8e0c2996f1aeecd58c00e9b099
ToppCell	droplet-Lung-3m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l4\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PTPRJ HCK RYR1 PLD4	1.03e-04	164	66	4	ea2897942ad72fba900c7ab354d6a9e203bf0e4a
ToppCell	facs-Lung-3m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l4\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PTPRJ HCK RYR1 PLD4	1.03e-04	164	66	4	11dfd84f5fb90de330858e1e852848832734e004
ToppCell	facs-Heart-RA-24m-Lymphocytic-B_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL24 HCK RYR1 PLD4	1.05e-04	165	66	4	36415924d05373e9dd3665be599f4f3f40bf0497
ToppCell	facs-Heart-RA-24m-Lymphocytic-B_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL24 HCK RYR1 PLD4	1.05e-04	165	66	4	56310fddd3d8e4afdfde066d26cee9747e5b8c6a
ToppCell	droplet-Bladder-nan-3m-Hematologic-granulocyte-monocyte_progenitor\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD226 HCK RYR1 PLD4	1.08e-04	166	66	4	e01c720de6d4ca144c55378e023e718a64bf32f6
ToppCell	5'-Adult-Appendix-Hematopoietic-Myeloid-cDC2\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NLRP12 CD1D IL22RA2 PLD4	1.10e-04	167	66	4	1bd0aa7a3c8649f342bb856cf861c4c5984ad889
ToppCell	LPS-antiTNF-Myeloid-Dendritic_cells-mDC\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CD226 MTHFD2 HCK PLD4	1.13e-04	168	66	4	2dca1c4a33b6da9357fa3b2a523af19baab1c21c
ToppCell	droplet-Lung-18m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l4\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PTPRJ HCK RYR1 PLD4	1.13e-04	168	66	4	4b5be7c6662eceddf90a65015f12908278d1664e
ToppCell	BAL-Severe-Myeloid-cDC-cDC-cDC_4\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	CD1D RYR1 PLD4 EEF1A2	1.13e-04	168	66	4	d60f7cd8269f373827f49c7785002cb38e4570a9
ToppCell	droplet-Lung-18m-Hematologic-myeloid-non-classical_monocyte\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PTPRJ HCK RYR1 PLD4	1.13e-04	168	66	4	689c41f6e9f65381570991cc311cba49a57ec955
ToppCell	droplet-Lung-nan-18m-Myeloid-non-classical_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRJ HCK RYR1 PLD4	1.15e-04	169	66	4	ba023ee7bb165c2bfbefc2d969ff32ca1eeed33b
ToppCell	BAL-Severe-Myeloid-cDC-cDC-cDC_4\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CD1D RYR1 PLD4 EEF1A2	1.15e-04	169	66	4	ccd98f9005aa0a88bd49f153be4e7200cc3dd0ac
ToppCell	droplet-Lung-LUNG-30m-Myeloid-Nonclassical_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRJ HCK RYR1 PLD4	1.15e-04	169	66	4	411556e93adcbb7e4d79b02f3dc72963ec8a0759
ToppCell	droplet-Lung-nan-18m-Myeloid-Nonclassical_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRJ HCK RYR1 PLD4	1.15e-04	169	66	4	c96e0f3241d13926dbee9f91c0c8c5bfa7479a0d
ToppCell	droplet-Lung-LUNG-30m-Myeloid-non-classical_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRJ HCK RYR1 PLD4	1.15e-04	169	66	4	39b1acfd099abb9de18c29c05c7a67709ea76775
ToppCell	droplet-Lung-21m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l4\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PTPRJ HCK RYR1 PLD4	1.15e-04	169	66	4	b059304543876f514d5c7214f1f0a2da00f10a67
ToppCell	droplet-Lung-21m-Hematologic-myeloid-non-classical_monocyte\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PTPRJ HCK RYR1 PLD4	1.15e-04	169	66	4	945f737984c4de70a4e9c214053b005358053dd5
ToppCell	droplet-Lung-1m-Hematologic-myeloid-intermediate_monocyte-intermediate_monocyte_l4\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PTPRJ HCK RYR1 PLD4	1.18e-04	170	66	4	4d28dc9eb572f43809619f923978cd7494853d43
ToppCell	droplet-Lung-1m-Hematologic-myeloid-intermediate_monocyte\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PTPRJ HCK RYR1 PLD4	1.21e-04	171	66	4	ed5886d6aa87b2d73469d39dc217227bd4d4c918
ToppCell	droplet-Lung-1m-Hematologic-myeloid-non-classical_monocyte\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PTPRJ HCK RYR1 PLD4	1.21e-04	171	66	4	00739085fdbc4d64c9faacba2c2adeab580dd2b1
ToppCell	droplet-Lung-nan-21m-Myeloid-non-classical_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRJ HCK RYR1 PLD4	1.24e-04	172	66	4	51bea97564a33f0060c546c9be4bf8bf8f1660f6
ToppCell	droplet-Lung-1m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l4\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PTPRJ HCK RYR1 PLD4	1.24e-04	172	66	4	5f58ff6cac32546d07b2a49ed250b6c7aa417188
ToppCell	droplet-Lung-nan-21m-Myeloid-Nonclassical_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRJ HCK RYR1 PLD4	1.24e-04	172	66	4	be4dd4ba8d7a651677c797c25fd75f14e627415a
ToppCell	367C-Fibroblasts-Fibroblast-J_(Lipofibroblast)\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	IL24 CNKSR3 RYR1 IGSF3	1.26e-04	173	66	4	3d7c281a1a9f183a5a861d1a9c7b50d216535893
ToppCell	367C-Fibroblasts-Fibroblast-J_(Lipofibroblast)-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	IL24 CNKSR3 RYR1 IGSF3	1.26e-04	173	66	4	3aa90578371039f81b7c6fa873ec70f8f2bc7dfa
ToppCell	LPS-antiTNF-Lymphocytic_B\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SLC15A2 EIF2AK3 PLD4 EEF1A2	1.29e-04	174	66	4	cc493654ea3517bc6a145c7f787f304929636f86
ToppCell	LPS-antiTNF-Lymphocytic_B-B_cells-B-cells\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SLC15A2 EIF2AK3 PLD4 EEF1A2	1.29e-04	174	66	4	9eb3504f9340517ef5d056503044fbdb9ffeb714
ToppCell	LPS-antiTNF-Lymphocytic_B-B_cells\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SLC15A2 EIF2AK3 PLD4 EEF1A2	1.29e-04	174	66	4	b4c2d1c029fcd0d4926aa79a5b789c713919dcf3
ToppCell	LPS_only-Lymphocytic_B-B_cells\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SLC15A2 EIF2AK3 PLD4 EEF1A2	1.38e-04	177	66	4	c82332c5f656aa26513e4f7525d5d4d733019725
ToppCell	LPS_only-Lymphocytic_B\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SLC15A2 EIF2AK3 PLD4 EEF1A2	1.38e-04	177	66	4	5ed65e08d773d157840317c72e0d43c261d438d4
ToppCell	LPS_only-Lymphocytic_B-B_cells-B-cells\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SLC15A2 EIF2AK3 PLD4 EEF1A2	1.38e-04	177	66	4	8a955a7ab84c434f9ad4b467246b8be3cb479406
ToppCell	facs-Spleen-nan-3m-Lymphocytic-CD8-positive,_alpha-beta_T_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAM78A CD226 SLC12A7 IL6ST	1.38e-04	177	66	4	ac0cf03e2a1baf84db3ae245d59bbc6ae52c13be
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Hematopoietic-Myeloid-Macrophages\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NLRP12 CD226 HCK PLD4	1.44e-04	179	66	4	ae9d90a4eac2cfa545a764df84914c5801544278
ToppCell	3'-Adult-LargeIntestine-Epithelial-Tuft-related-Tuft\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CWH43 PTPRJ HCK IGSF3	1.44e-04	179	66	4	906555ce2ca264a0215b120c7ff7c9b411de6a34
ToppCell	CD8+_Memory_T_cell-FLU-5\|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster	ANKRD13B ZFYVE9 CDHR3 IGSF3	1.44e-04	179	66	4	7f18dffa85285599662edbcd3f32ab42672bffb8
ToppCell	metastatic_Brain-Myeloid_cells-CD207+CD1a+_LCs\|metastatic_Brain / Location, Cell class and cell subclass	IL22RA2 HCK PLD4 MYBPC3	1.47e-04	180	66	4	51727cb66fe7a7709453f7026e0ff3d6c93d5aa5
ToppCell	COVID-19-kidney-tDL\|COVID-19 / Disease (COVID-19 only), tissue and cell type	DOK6 CDHR3 KLHL13 CNKSR3	1.47e-04	180	66	4	864c895b5eaedefae86f5829fa344f7b686fb59f
ToppCell	normal_Lymph_Node-Myeloid_cells-Pleural_Mac\|normal_Lymph_Node / Location, Cell class and cell subclass	NLRP12 CD1D HCK MYBPC3	1.50e-04	181	66	4	921e917f83105896ad8918dc134b871708024021
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Epithelial-neuronal_stem_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ELOVL4 KANK1 CNKSR3 IGSF3	1.50e-04	181	66	4	4e81ec1580e9acb22c32c465eb46f83d1e9e424e
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Epithelial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ELOVL4 KANK1 CNKSR3 IGSF3	1.50e-04	181	66	4	ad30c01290fb98adbd0caed301a584761212c977
ToppCell	ILEUM-non-inflamed-(3)_DC1\|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	CD1D IL22RA2 HCK PLD4	1.50e-04	181	66	4	c9f53720249c8569598cc859e43e35c5f3f8475a
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Epithelial-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ELOVL4 KANK1 CNKSR3 IGSF3	1.50e-04	181	66	4	3a3268a4dff8ffcb79e09f46490e138c96f8d916
ToppCell	B_cells-ABCs\|B_cells / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	ANKRD13B DNAH8 HCK PLD4	1.57e-04	183	66	4	bf9c6fe3ce4e44e4056027257eab8448c39c4fb8
ToppCell	3'_v3-GI_small-bowel-Myeloid_Dendritic-DC2\|GI_small-bowel / Manually curated celltypes from each tissue	CD1D IL22RA2 HCK PLD4	1.57e-04	183	66	4	c94ee9f35b21252e1ab5ab15b6a2ce69a7d753f7
ToppCell	3'_v3-GI_small-bowel-Myeloid_Dendritic\|GI_small-bowel / Manually curated celltypes from each tissue	CD1D IL22RA2 STARD8 HCK	1.57e-04	183	66	4	6109199cf25b28831193a5ed7925b5bf38c6eb43
ToppCell	Nasal_Brush-Immune-Dendritic_cells\|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X	CD1D CD226 HCK PLD4	1.57e-04	183	66	4	b1daec831990a53e846c089cebfcf4f8440820e4
ToppCell	wk_08-11-Epithelial-PNS-PCP4+_neuron\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	ELOVL4 KLHL13 DPYSL5 EEF1A2	1.60e-04	184	66	4	eac2a9089913f33a961ba11519b53645790f2056
ToppCell	3'-Airway_Nasal-Immune_Myeloid\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CD1D IL22RA2 HCK PLD4	1.63e-04	185	66	4	f1b555a0acc93c51e48fbe290f820ddc2c58e0d7
ToppCell	10x5'-GI_small-bowel-Myeloid_Dendritic-DC2\|GI_small-bowel / Manually curated celltypes from each tissue	CD1D IL22RA2 HCK PLD4	1.63e-04	185	66	4	f78be85dd6e443abb7af20f98ff351c1131ece4d
ToppCell	facs-Skin-Anagen-3m-Epithelial-nan\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ELOVL4 IL22RA2 CWH43 MTHFD2	1.67e-04	186	66	4	9a7932d0a208f3997216bd21a72913cc82b59fc9
ToppCell	5'-Adult-LargeIntestine-Hematopoietic-Myeloid-cDC2\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CD1D IL22RA2 HCK PLD4	1.67e-04	186	66	4	69b107ad88b07e9aeef09d4e4dac99b0cb6b467e
ToppCell	PCW_05-06-Hematologic_Myeloid-Hem_Myeloid_monocytic-im_myeloid_progenitor3_(13)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	CD1D HCK RYR1 PLD4	1.67e-04	186	66	4	6575ec6a626cdea169ffd185d47828dfaa29475d
ToppCell	3'-Pediatric_IBD-SmallIntestine-Hematopoietic-Myeloid-cDC2\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CD1D IL22RA2 HCK PLD4	1.67e-04	186	66	4	44785bd171f424ad61437275026439fae3cb8d8c
ToppCell	droplet-Spleen-nan-3m-Lymphocytic-T_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAM78A CD226 SLC12A7 DNAH8	1.70e-04	187	66	4	1387981d224cb9e846ed18e366736855a4eb827e
ToppCell	control-Myeloid-Resident_Macrophage\|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	CD1D STARD8 HCK PLD4	1.74e-04	188	66	4	9bcd6a83da912d136745d1abcb34b3735141048c
ToppCell	5'-GW_trimst-2-LymphNode-Hematopoietic-Myeloid-Monocytes\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NLRP12 CD1D HCK PLD4	1.74e-04	188	66	4	085b61dfad373e5c39f2496539fbfed1b588115a
ToppCell	PCW_05-06-Hematologic_Myeloid-Hem_Myeloid_monocytic-im_myeloid_progenitor2_(3)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	CD1D HCK RYR1 PLD4	1.74e-04	188	66	4	f4d11d06be46f13adbf36d94bc2bdcd14d0bfa75
ToppCell	metastatic_Lymph_Node-Myeloid_cells-CD163+CD14+_DCs\|metastatic_Lymph_Node / Location, Cell class and cell subclass	IL22RA2 MTHFD2 HCK PLD4	1.74e-04	188	66	4	5d12afb483d028ca02b3b4215131f6128e8bcd48
ToppCell	3'-Adult-LargeIntestine-Hematopoietic-Myeloid-cDC2\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CD1D IL22RA2 HCK PLD4	1.77e-04	189	66	4	8419d62e6991851bdc6ad861f5c9086ff808b222
ToppCell	LV-14._Fibroblast_III\|World / Chamber and Cluster_Paper	EPHB2 DOK6 EIF2AK3 LEPR	1.77e-04	189	66	4	3922135d1f6fc768d71ba3b465585fead6ea68a8
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Hematopoietic-Myeloid-Monocytes\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CD1D CD226 HCK PLD4	1.77e-04	189	66	4	a010f3e4da6e9bb23b0b9a7f82ad5cee4e607ecd
ToppCell	Control-B_intermediate-6\|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)	PTPRJ HCK PLD4 FBXW7	1.77e-04	189	66	4	11cb9a16f1de8f60af2073ed7ea6d4f41c02f299
ToppCell	RV-15._Ventricular_Cardiomyocyte_III\|World / Chamber and Cluster_Paper	CNKSR3 EIF2AK3 FBXW7 MYBPC3	1.77e-04	189	66	4	0a82931b5f6c0a6427ca3edd5e2235ac49099d40
ToppCell	RV-15._Ventricular_Cardiomyocyte_III\|RV / Chamber and Cluster_Paper	CNKSR3 EIF2AK3 FBXW7 MYBPC3	1.81e-04	190	66	4	93c3188dfeb0b2f9889f8ae9b9c1f2f34129c99b
Disease	developmental and epileptic encephalopathy 33 (implicated_via_orthology)	EEF1A1 EEF1A1P5 EEF1A2	9.28e-09	3	63	3	DOID:0080463 (implicated_via_orthology)
Disease	Albuminuria	NCK1 LEPR NCK2	1.82e-05	24	63	3	C0001925
Disease	Nephrotic Syndrome	KANK1 NCK1 NCK2	2.62e-05	27	63	3	C0027726
Disease	epilepsy (implicated_via_orthology)	SLC13A4 SLC12A7 EEF1A1 EEF1A1P5 EEF1A2	2.62e-05	163	63	5	DOID:1826 (implicated_via_orthology)
Disease	CD226 antigen measurement	NLRP12 CD226	9.36e-05	7	63	2	EFO_0020246
Disease	thrombin generation potential measurement	PTPRJ MYBPC3	2.44e-04	11	63	2	EFO_0005538
Disease	mean platelet volume	STARD8 UBN1 PTPRJ CD226 SLC12A7 LEPR NCK2 EEF1A1P5 MYBPC3	3.01e-04	1020	63	9	EFO_0004584
Disease	fasting blood glucose measurement	NLRP12 KANK1 DPYSL5 LEPR EEF1A2	3.73e-04	287	63	5	EFO_0004465
Disease	acute lymphoblastic leukemia	WDR19 MAGI2 PTPRJ	3.86e-04	66	63	3	EFO_0000220
Disease	response to acetylsalicylate	DOK6 CNKSR3	5.28e-04	16	63	2	GO_1903492
Disease	dilated cardiomyopathy (implicated_via_orthology)	EEF1A1 EEF1A1P5 EEF1A2	6.78e-04	80	63	3	DOID:12930 (implicated_via_orthology)
Disease	age at voice drop	IGSF1 LEPR	1.01e-03	22	63	2	EFO_0007888
Disease	monocyte count	NLRP12 CD1D CD226 SPDEF NCK1 LEPR RYR1 EEF1A1P5 MYBPC3	1.87e-03	1320	63	9	EFO_0005091
Disease	Ovarian Mucinous Adenocarcinoma	TRRAP HCK	2.00e-03	31	63	2	C1335167
Disease	fear of minor pain measurement	HCK TRMT12	2.00e-03	31	63	2	EFO_0008340

Protein segments in the cluster

Peptide	Gene	Start	Entry
NAWLEAPPEKWQEKM	EIF2AK3	656	Q9NZJ5
APPEKWQEKMDEIWL	EIF2AK3	661	Q9NZJ5
PEKHIVMKWRFKSWP	AHSA1	266	O95433
WKNWLQKITEMKPEE	ANKIB1	481	Q9P2G1
WVPEMQDPQSWKGKE	ADAMTS13	1411	Q76LX8
IPSNMWVEAWETAKP	RAB3GAP1	731	Q15042
VEMKWEFTSWVPLVS	ANKRD13B	131	Q86YJ7
LPNTLKDFWRMVWEK	PTPRJ	1116	Q12913
SPWKTPKPIMDRWEN	MAGI2	686	Q86UL8
VMDVIEKPENDPEWW	NCK1	216	P16333
TMEVIEKPENDPEWW	NCK2	221	O43639
WLGPKWMKDREPFQM	ELOVL4	61	Q9GZR5
PPFQKWIWMNLESPT	FUT9	126	Q9Y231
VEWMSKLAKFKPLWI	ENOSF1	261	Q7L5Y1
TFPNWMENPWVKVDT	EPHB2	126	P29323
WWKLVHNKPPTMKPE	KAT14	201	Q9H8E8
GRVLWQWTKVKMLPT	DNAH8	2636	Q96JB1
KDEWTMVSPLPCAWQ	KBTBD2	406	Q8IY47
KNKVVGPELPMNWWI	KANK1	556	Q14678
KENKIVPSKEIVWWM	LEPR	356	P48357
VPSKEIVWWMNLAEK	LEPR	361	P48357
RFTPWWETKIDPPVM	IL22RA2	151	Q969J5
EKMIWWANKDPLPPL	GCN1	2571	Q92616
NEWKMVSPMPWKGVT	KLHL7	506	Q8IXQ5
WKWMITKKPPTVSES	GPR151	321	Q8TDV0
WKNKFWGKSMEILPV	OSBPL6	696	Q9BZF3
MLKPLWKAAVAPTWP	PLD4	1	Q96BZ4
CMSSKPQKPWEKDAW	HCK	241	P08631
MIWVTDTFPKPWLFA	IGSF1	961	Q8N6C5
MVEWFVWKPNHPERE	IGSF3	851	O75054
KAFPKDNMLWVEWTT	IL6ST	431	P40189
MPLKWKTSSPAIWKF	KLHL13	1	Q9P2N7
LKTVPQRMWSHFWKV	BFAR	386	Q9NZS9
LWDIHNAKVKLVMWP	DOK6	166	Q6PKX4
PKPVWVKWMRGEQEQ	CD1D	231	P15813
WKDPLTQMPKWKESS	CDHR3	801	Q6ZTQ4
PNMPWFKGWKVERKE	EEF1A2	206	Q05639
MLEPSANMPWFKGWK	EEF1A1	201	P68104
EWLKMFQSWSGPEKL	FBXW7	236	Q969H0
PQKLWEAFWAVKDTM	IL24	66	Q13007
MLEPSANMPWFKGWK	EEF1A1P5	201	Q5VTE0
LVMPKLIPEHWEKWE	LINC01545	61	Q5VT33
MTWPVQAVRWEKIQP	CD226	156	Q15762
VLMAWPASWKQEDNP	SLC12A7	791	Q9Y666
PIITWKDFQKTMPWE	SLC13A4	451	Q9UKG4
WKIEDIPANKMSIAW	SLC15A2	596	Q16348
RWPIKESLKAMIAWE	RYR1	2806	P21817
WWAPKVKAEMETLVR	DPYSL5	136	Q9BPU6
TITPFWKLVNKKWML	CWH43	56	Q9H720
KWPFWLSPRQVMVVP	TARS1	611	P26639
NKATQPMKSVLWWLP	SUMF2	106	Q8NBJ7
PMKSVLWWLPVEKAF	SUMF2	111	Q8NBJ7
VMPPIPKKETWVVGW	FAM78A	76	Q5JUQ0
SMLPATPWGVWEIIK	MTHFD2	171	P13995
NKEHLWKMWSVIVTP	RIF1	641	Q5UIP0
PTIKGVLWENWPMDK	WDR19	556	Q8NEZ3
TVPHKQGWVWSMPKF	STARD8	541	Q92502
MEPVTKWSPKQVVDW	CNK3/IPCEF1	1	G9CGD6
MEPVTKWSPKQVVDW	CNKSR3	1	Q6P9H4
FMETEVKPLWPKGWM	UBN2	641	Q6ZU65
WMVIKEILEGPSPEW	ZNF287	226	Q9HBT7
DPMDWSPSNVQKWLL	SPDEF	146	O95238
STKDWKMAPKLIWPE	ZNF75CP	186	Q92670
EVKPLWPKGWMQART	UBN1	556	Q9NPG3
SQWDSPMRVKLSIWK	VPS13B	2961	Q7Z7G8
GKMLSPATKPEWQRW	TRMT12	381	Q53H54
PDMWPKSELKLQWFD	TRRAP	2136	Q9Y4A5
KWETPWAKVFPIRLM	ZFYVE9	1061	O95405
WKVSPHIKMDLLQWI	NLRP12	581	P59046
PPVVKWFKGKWVDLS	MYBPC3	186	Q14896