Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionmethyl-CpG binding

MBD3L5 ZBTB33 MBD3L2 MBD3L3 MBD3L4 MBD3L2B

1.74e-07311646GO:0008327
GeneOntologyMolecularFunctionprotein serine kinase activity

CDC42BPA CDK12 SNRK WNK1 PIKFYVE TTBK2 SIK2 MASTL MAP3K9 TNK2 MAP2K7

2.12e-0436316411GO:0106310
GeneOntologyBiologicalProcessDNA methylation-dependent constitutive heterochromatin formation

MBD3L5 MBD3L2 MBD3L3 MBD3L4 MBD3L2B BAZ2A ATF7IP

5.51e-08441657GO:0006346
GeneOntologyBiologicalProcessfacultative heterochromatin formation

MBD3L5 MBD3L2 MBD3L3 MBD3L4 MBD3L2B BAZ2A ATF7IP

2.71e-07551657GO:0140718
GeneOntologyBiologicalProcessheterochromatin formation

MBD3L5 MBD3L2 MBD3L3 MBD3L4 MBD3L2B BAZ2A ATF7IP DOT1L UTY

6.73e-061631659GO:0031507
GeneOntologyBiologicalProcessnegative regulation of gene expression, epigenetic

MBD3L5 MBD3L2 MBD3L3 MBD3L4 MBD3L2B BAZ2A ATF7IP DOT1L UTY

3.87e-052031659GO:0045814
DomainSEA

MUC16 MUC13 MUC17 MUC3A IMPG2

8.67e-08141625SM00200
DomainMeCpG-bd_2/3_C_dom

MBD3L5 MBD3L2 MBD3L3 MBD3L4

1.87e-0771624IPR025884
DomainMBD2/MBD3_p55-bd

MBD3L5 MBD3L2 MBD3L3 MBD3L4

1.87e-0771624IPR032343
DomainMBDa

MBD3L5 MBD3L2 MBD3L3 MBD3L4

1.87e-0771624PF16564
DomainMBD_C

MBD3L5 MBD3L2 MBD3L3 MBD3L4

1.87e-0771624PF14048
DomainSEA

MUC16 MUC13 MUC17 MUC3A IMPG2

1.37e-06231625PS50024
DomainSEA_dom

MUC16 MUC13 MUC17 MUC3A IMPG2

1.37e-06231625IPR000082
DomainLRRC37AB_C

LRRC37A3 LRRC37A2 LRRC37A

2.55e-0641623IPR029423
DomainLRRC37AB_C

LRRC37A3 LRRC37A2 LRRC37A

2.55e-0641623PF14914
DomainLRRC37_N

LRRC37A3 LRRC37A2 LRRC37A

2.55e-0641623IPR032754
DomainLRRC37

LRRC37A3 LRRC37A2 LRRC37A

2.55e-0641623PF15779
DomainLRRC37A/B-like

LRRC37A3 LRRC37A2 LRRC37A

2.55e-0641623IPR015753
DomainEGF_3

FAT4 MUC13 CELSR1 FAT2 HEG1 HMCN2 MUC17 ASTN1 MUC3A OTOG IMPG2

6.68e-0623516211PS50026
DomainLaminin_G

FAT4 COL9A1 COL24A1 CELSR1 FAT2 CSPG4

1.08e-05581626IPR001791
DomainEGF-like_dom

FAT4 MUC13 CELSR1 FAT2 HEG1 HMCN2 MUC17 ASTN1 MUC3A OTOG IMPG2

1.15e-0524916211IPR000742
DomainLAM_G_DOMAIN

FAT4 COL24A1 CELSR1 FAT2 CSPG4

1.84e-05381625PS50025
DomainLaminin_G_2

FAT4 COL24A1 CELSR1 FAT2 CSPG4

2.38e-05401625PF02210
DomainSEA

MUC16 MUC13 MUC17 IMPG2

3.53e-05221624PF01390
DomainEGF_1

FAT4 MUC13 CELSR1 FAT2 HEG1 HMCN2 MUC17 ASTN1 MUC3A IMPG2

7.93e-0525516210PS00022
DomainEGF-like_CS

FAT4 MUC13 CELSR1 FAT2 HEG1 HMCN2 MUC17 ASTN1 MUC3A IMPG2

9.62e-0526116210IPR013032
DomainEGF_2

FAT4 MUC13 CELSR1 FAT2 HEG1 HMCN2 MUC17 ASTN1 MUC3A IMPG2

1.09e-0426516210PS01186
Domain-

FAT4 COL9A1 COL24A1 CELSR1 FAT2 CSPG4

1.78e-049516262.60.120.200
Domain-

MUC16 MUC17 IMPG2

2.70e-041516233.30.70.960
DomainLamG

FAT4 CELSR1 FAT2 CSPG4

5.65e-04441624SM00282
DomainLRR_8

LRRC37A3 MFHAS1 LRRC37A2 LRCH3 LRRC37A PHLPP2 LGI1

7.40e-041711627PF13855
DomainLRR_TYP

LRRC37A3 MFHAS1 LRRC37A2 LRCH3 LRRC37A PHLPP2 LGI1

9.07e-041771627SM00369
DomainLeu-rich_rpt_typical-subtyp

LRRC37A3 MFHAS1 LRRC37A2 LRCH3 LRRC37A PHLPP2 LGI1

9.07e-041771627IPR003591
DomainEGF

FAT4 MUC13 CELSR1 FAT2 HEG1 MUC17 ASTN1 MUC3A

1.05e-032351628SM00181
PathwayREACTOME_DEFECTIVE_GALNT3_CAUSES_HFTC

MUC16 MUC13 MUC17 MUC3A MUC6

1.53e-07161185M27410
PathwayREACTOME_DEFECTIVE_C1GALT1C1_CAUSES_TNPS

MUC16 MUC13 MUC17 MUC3A MUC6

2.15e-07171185M27412
PathwayREACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS

MUC16 MUC13 MUC17 MUC3A MUC6

1.13e-06231185M556
PathwayREACTOME_DECTIN_2_FAMILY

MUC16 MUC13 MUC17 MUC3A MUC6

2.16e-06261185M27483
PathwayREACTOME_DISEASES_OF_GLYCOSYLATION

MPDU1 MUC16 MUC13 B4GALT1 MUC17 CSPG4 ALG8 MUC3A MUC6

3.09e-061431189M27275
PathwayREACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS

MUC16 MUC13 MUC17 MUC6

2.50e-05211184MM15706
PathwayREACTOME_DISEASES_OF_METABOLISM

CYP1B1 MPDU1 MUC16 MUC13 B4GALT1 MUC17 CSPG4 ALG8 MUC3A MUC6

4.68e-0525011810M27554
PathwayREACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS

MUC16 MUC13 MUC17 MUC3A MUC6

1.67e-04621185M546
PathwayREACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS

MUC16 MUC13 MUC17 MUC3A MUC6

2.58e-04681185M27303
Pubmed

MBD3L1 and MBD3L2, two new proteins homologous to the methyl-CpG-binding proteins MBD2 and MBD3: characterization of MBD3L1 as a testis-specific transcriptional repressor.

MBD3L5 MBD3L2 MBD3L3 MBD3L4 MBD3L2B

1.67e-116172512504854
Pubmed

Haploid male germ cell- and oocyte-specific Mbd3l1 and Mbd3l2 genes are dispensable for early development, fertility, and zygotic DNA demethylation in the mouse.

MBD3L5 MBD3L2 MBD3L3 MBD3L4 MBD3L2B

1.67e-116172518942147
Pubmed

MBD3L2 interacts with MBD3 and components of the NuRD complex and can oppose MBD2-MeCP1-mediated methylation silencing.

MBD3L5 MBD3L2 MBD3L3 MBD3L4 MBD3L2B

8.05e-0915172515701600
Pubmed

Mucin gene expression in human laryngeal epithelia: effect of laryngopharyngeal reflux.

MUC16 MUC13 MUC17 MUC3A MUC6

2.27e-0818172518834073
Pubmed

Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.

ATMIN MPDU1 POU2F1 RICTOR TSC22D2 FCHO2 WNK1 VIRMA MRPL35 USP14 CNNM3 CRACD SETD2 PRDM10 LLGL2 GTF2I ARHGEF7 SCAPER ALG8 MAML2 MAP2K7 NIPBL FBXW7

1.86e-0713271722332694731
Pubmed

Primate segmental duplication creates novel promoters for the LRRC37 gene family within the 17q21.31 inversion polymorphism region.

LRRC37A3 LRRC37A2 LRRC37A

4.74e-074172322419166
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

ATMIN ARHGEF12 GRB10 FHIP2A VIRMA UNC5A CRACD BAZ2A NAV1 RIPOR1 ADGRL3 SON

9.87e-074071721212693553
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

CLIP2 PPFIBP1 PTPN23 RICTOR WNK1 PIKFYVE SETD2 KRBA1 FAT2 USF3 SBF2 SCAPER LNPK

1.20e-064931721315368895
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

DMTF1 ACACB TSC22D2 WNK1 USF3 SAP30BP TNK2 MAML2 SAP130 ADGRL3 CRTC2 SON

1.75e-064301721235044719
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

ATMIN ARSJ CDC42BPA MFHAS1 CDK12 GRB10 WNK1 PIKFYVE DIP2A CELSR1 HEG1 LLGL2 SBF2 CSPG4 IFRD2 NAV1 TNK2 RIPOR1 DOT1L

2.65e-0611051721935748872
Pubmed

A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

CDK12 GRB10 FCHO2 WNK1 DENND4C CHMP7 GTF2I GMEB1 MASTL ELF1 NIPBL SON

8.60e-065031721216964243
Pubmed

Evolutionary dynamism of the primate LRRC37 gene family.

LRRC37A3 LRRC37A2 LRRC37A

1.39e-0510172323064749
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

BCL9L ACACB PPFIBP1 KIAA1549 RICTOR WNK1 DENND4C LRCH3 NAV1 CEP295 CRTC2

1.51e-054461721124255178
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

ATMIN EP400P1 CDC42BPA GRB10 ZNF385B LRCH3 B4GALT1 DNAH1 USP14 USF3 GTF2I EFNB2 TECPR2 SBF2 NAV1 TNK2 RIPOR1 TRMT13 PCDH1 SAP130 RECK

1.61e-0514891722128611215
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

CYP1B1 BCL9L CDC42BPA CDK12 PPFIBP1 ARHGEF12 RICTOR DHX33 VIRMA LRCH3 TRIM33 CRACD SETD2 CELSR1 BAZ2A SUPT7L IFRD2 SAP30BP NIPBL DNASE1L1 SON

1.74e-0514971722131527615
Pubmed

Differences in the constitutive and SIV infection induced expression of Siglecs by hematopoietic cells from non-human primates.

SIGLEC7 CD33

2.43e-052172218331725
Pubmed

Tumor-suppressor Fbxw7 targets SIK2 for degradation to interfere with TORC2-AKT signaling in pancreatic cancer.

SIK2 FBXW7

2.43e-052172232437091
Pubmed

Partial monosomy 9p (9p22.2-->pter) and partial trisomy 18q (18q21.32-->qter) in a female infant with anorectal malformations.

PIGN FREM1

2.43e-052172222876578
Pubmed

Regulation of myeloid cell proliferation and survival by p75/AIRM1 and CD33 surface receptors.

SIGLEC7 CD33

2.43e-052172211774609
Pubmed

KIAA1429 promotes the progression of lung adenocarcinoma by regulating the m6A level of MUC3A.

VIRMA MUC3A

2.43e-052172233249400
Pubmed

Pathogenic variations in MAML2 and MAMLD1 contribute to congenital hypothyroidism due to dyshormonogenesis by regulating the Notch signalling pathway.

MAMLD1 MAML2

2.43e-052172236898841
Pubmed

NG2 and phosphacan are present in the astroglial scar after human traumatic spinal cord injury.

PTPRZ1 CSPG4

2.43e-052172219604403
Pubmed

SnoN suppresses TGF-β-induced epithelial-mesenchymal transition and invasion of bladder cancer in a TIF1γ-dependent manner.

SKIL TRIM33

2.43e-052172227430247
Pubmed

Engagement of p75/AIRM1 or CD33 inhibits the proliferation of normal or leukemic myeloid cells.

SIGLEC7 CD33

2.43e-052172210611343
Pubmed

Pax6 interactions with chromatin and identification of its novel direct target genes in lens and forebrain.

FAT4 EFNB2 NAV1

2.53e-0512172323342162
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

CDC42BPA PPFIBP1 GRB10 RICTOR RFX7 WNK1 VIRMA DENND4C SRGAP1 SIK2 MAP3K9 NAV1 MAP2K7 CRTC2 OTOG

2.71e-058611721536931259
Pubmed

A human MAP kinase interactome.

CDC42BPA CLIP2 PTPN23 WNK1 FAM13B USF3 ARHGEF7 ATF7IP NAV1 TNK2 BICRAL

3.32e-054861721120936779
Pubmed

A set of proteins interacting with transcription factor Sp1 identified in a two-hybrid screening.

POU2F1 ATF7IP ELF1

4.16e-0514172310976766
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

EP400P1 ZBTB33 KIAA1549 RICTOR SKIL TRIM33 SETD2 HMCN2 BAZ2A SUPT7L SAP30BP SCAPER CEP295 BICRAL MAP2K7 SAP130 SON

4.24e-0511161721731753913
Pubmed

Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.

KIAA1549 GRB10 HSPA12A SCAPER NAV1 BICRAL

4.82e-05130172612421765
Pubmed

SnoN facilitates ALK1-Smad1/5 signaling during embryonic angiogenesis.

SKIL EFNB2 HEY2

5.18e-0515172324019535
Pubmed

Identification of the SOX2 Interactome by BioID Reveals EP300 as a Mediator of SOX2-dependent Squamous Differentiation and Lung Squamous Cell Carcinoma Growth.

CDK12 POU2F1 GTF2I SAP130 NIPBL

5.93e-0583172528794006
Pubmed

A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.

GRB10 APBA3 SNRK RICTOR FCHO2 FHIP2A WNK1 DENND4C CHMP7 TRIM33 SETD2 SBF2 SIK2 RIPOR1 MAP2K7 CRTC2

6.26e-0510381721626673895
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

ZBTB33 ACACB CDK12 PTPN23 WNK1 USP14 CRACD SETD2 GTF2I BAZ2A ATF7IP SAP30BP MASTL NIPBL SON

6.79e-059341721533916271
Pubmed

Genomic organization and structure of the 3' region of human MUC3: alternative splicing predicts membrane-bound and soluble forms of the mucin.

MUC17 MUC3A

7.27e-053172210512748
Pubmed

Identification of CELSR1 as a susceptibility gene for ischemic stroke in Japanese individuals by a genome-wide association study.

CELSR1 LLGL2

7.27e-053172219403135
Pubmed

SIK2 represses AKT/GSK3β/β-catenin signaling and suppresses gastric cancer by inhibiting autophagic degradation of protein phosphatases.

SIK2 PHLPP2

7.27e-053172233128264
Pubmed

Significance of YAP1-MAML2 rearrangement and GTF2I mutation in the diagnosis and differential diagnosis of metaplastic thymoma.

GTF2I MAML2

7.27e-053172237489594
Pubmed

SIK2 is critical in the regulation of lipid homeostasis and adipogenesis in vivo.

SIK2 CRTC2

7.27e-053172224898145
Pubmed

PIAS1 and TIF1γ collaborate to promote SnoN SUMOylation and suppression of epithelial-mesenchymal transition.

SKIL TRIM33

7.27e-053172232770107
Pubmed

Rictor regulates FBXW7-dependent c-Myc and cyclin E degradation in colorectal cancer cells.

RICTOR FBXW7

7.27e-053172222285861
Pubmed

The contribution of CLIP2 haploinsufficiency to the clinical manifestations of the Williams-Beuren syndrome.

CLIP2 GTF2I

7.27e-053172222608712
Pubmed

Octamer transcription factor-1 enhances hepatic nuclear factor-1alpha-mediated activation of the human UDP glucuronosyltransferase 2B7 promoter.

HNF1A POU2F1

7.27e-053172210779377
Pubmed

Immunoglobulin genes of different subgroups are interdigitated within the VK locus.

IGKV3D-11 IGKV3-11

7.27e-05317226440122
Pubmed

Genome-scale RNAi screen for host factors required for HIV replication.

ACACB WNK1 PRDM10 HMCN2 SBF2 IFRD2 MAP3K9 SLC24A1 UTY

8.43e-05361172918976975
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

FAT4 ACACB LRRC37A3 MPDU1 MUC16 VIRMA IL1RAPL1 TTBK2 SUPT7L CEP295 NIPBL UTY

8.64e-056381721231182584
Pubmed

A germline-specific class of small RNAs binds mammalian Piwi proteins.

COL9A1 LRRC37A2 POU2F1 SRR EYA3 TTBK2 SBF2 TNK2 DOT1L SON

8.85e-054501721016751776
Pubmed

Human transcription factor protein interaction networks.

BCL9L HNF1A ZBTB33 CDC42BPA ACACB POU2F1 PROSER1 EYA3 RFX7 TRIM33 GTF2I ATF7IP SUPT7L GMEB1 ELF1 DOT1L SAP130 NIPBL FBXW7

9.13e-0514291721935140242
Pubmed

Endothelial-specific expression of WNK1 kinase is essential for angiogenesis and heart development in mice.

WNK1 EFNB2 HEY2

9.18e-0518172319644017
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

SFXN4 RC3H2 CDK12 PPFIBP1 RICTOR FHIP2A PRSS3P2 DIP2A LLGL2 ARHGEF7 SIK2 CRTC2

1.03e-046501721238777146
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

CLIP2 CDK12 PPFIBP1 PTPN23 SNRK WNK1 SIK2

1.37e-04225172712168954
Pubmed

Endosomal phosphoinositides and human diseases.

PIKFYVE SBF2

1.45e-044172218429927
Pubmed

The adhesion GPCRs CELSR1-3 and LPHN3 engage G proteins via distinct activation mechanisms.

CELSR1 ADGRL3

1.45e-044172237224017
Pubmed

mRNA 5' region sequence incompleteness: a potential source of systematic errors in translation initiation codon assignment in human mRNAs.

DIP2A SON

1.45e-044172214637006
Pubmed

Mouse neuron navigator 1, a novel microtubule-associated protein involved in neuronal migration.

CLIP2 NAV1

1.45e-044172215797708
Pubmed

A systems-wide screen identifies substrates of the SCFβTrCP ubiquitin ligase.

DENND4C GTF2I SBF2 SIK2 NAV1 SON FBXW7

1.65e-04232172725515538
Pubmed

Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

PPFIBP1 CRACD PRDM10 HEG1 NAV1

1.65e-04103172510574462
Pubmed

A census of human transcription factors: function, expression and evolution.

DMTF1 RC3H2 HNF1A ZBTB33 KIAA1549 POU2F1 TSC22D2 RFX7 SKIL USF3 DMRT2 GMEB1 HEY2 ELF1

1.82e-049081721419274049
Pubmed

Melanoma chondroitin sulphate proteoglycan regulates cell spreading through Cdc42, Ack-1 and p130cas.

CSPG4 TNK2

2.41e-045172210587647
Pubmed

The AMPK-related kinase SIK2 is regulated by cAMP via phosphorylation at Ser358 in adipocytes.

SIK2 CRTC2

2.41e-045172222462548
Pubmed

Genomic organization of the siglec gene locus on chromosome 19q13.4 and cloning of two new siglec pseudogenes.

SIGLEC7 CD33

2.41e-045172211943481
Pubmed

Microglial CD33-related Siglec-E inhibits neurotoxicity by preventing the phagocytosis-associated oxidative burst.

SIGLEC7 CD33

2.41e-045172224227736
Pubmed

Involvement of SIK2/TORC2 signaling cascade in the regulation of insulin-induced PGC-1alpha and UCP-1 gene expression in brown adipocytes.

SIK2 CRTC2

2.41e-045172219351809
Pubmed

A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.

ACACB PPFIBP1 RICTOR FCHO2 LRCH3 CNNM3 HSPA12A LLGL2 EFNB2

2.66e-04421172936976175
Pubmed

The candidate splicing factor Sfswap regulates growth and patterning of inner ear sensory organs.

MAMLD1 HEY2 MAML2

2.84e-0426172324391519
Pubmed

Proteomic Analysis of the EWS-Fli-1 Interactome Reveals the Role of the Lysosome in EWS-Fli-1 Turnover.

BCL9L CDK12 PROSER1 EYA3 TRIM33 GTF2I ATF7IP SAP30BP NIPBL

2.85e-04425172924999758
Pubmed

TIF1γ protein regulates epithelial-mesenchymal transition by operating as a small ubiquitin-like modifier (SUMO) E3 ligase for the transcriptional regulator SnoN1.

SKIL TRIM33

3.60e-046172225059663
Pubmed

The FBXW7-SHOC2-Raptor Axis Controls the Cross-Talks between the RAS-ERK and mTORC1 Signaling Pathways.

RICTOR FBXW7

3.60e-046172230865892
Pubmed

14-3-3 proteins mediate inhibitory effects of cAMP on salt-inducible kinases (SIKs).

SIK2 CRTC2

3.60e-046172229211348
Pubmed

Expression of Muc19/Smgc gene products during murine sublingual gland development: cytodifferentiation and maturation of salivary mucous cells.

MUC16 MUC6

3.60e-046172219110483
Pubmed

Formation and maturation of the native cerebral collateral circulation.

EFNB2 CSPG4

3.60e-046172220346953
Pubmed

Mouse immunoglobulin chains. Pattern of sequence variation among kappa chains with limited sequence differences.

IGKV3D-20 IGKV3D-11

3.60e-04617224691517
Pubmed

Primary structures of N-terminal extra peptide segments linked to the variable and constant regions of immunoglobulin light chain precursors: implications on the organization and controlled expression of immunoglobulin genes.

IGKV3D-20 IGKV3D-11

3.60e-046172298179
Pubmed

Mechanisms of antibody diversity: multiple genes encode structurally related mouse kappa variable regions.

IGKV3D-20 IGKV3D-11

3.60e-046172299744
Pubmed

PtdIns5P regulation through evolution: roles in membrane trafficking?

PIKFYVE SBF2

3.60e-046172218774718
Pubmed

ATF7IP-Mediated Stabilization of the Histone Methyltransferase SETDB1 Is Essential for Heterochromatin Formation by the HUSH Complex.

ZBTB33 ATF7IP

3.60e-046172227732843
Pubmed

Rictor Undergoes Glycogen Synthase Kinase 3 (GSK3)-dependent, FBXW7-mediated Ubiquitination and Proteasomal Degradation.

RICTOR FBXW7

3.60e-046172225897075
Pubmed

Oncogenic RAS directs silencing of tumor suppressor genes through ordered recruitment of transcriptional repressors.

BAZ2A MAP3K9 DOT1L

3.95e-0429172324105743
Pubmed

Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.

BCL9L ZBTB33 SKIL TRIM33 SUPT7L SAP130 NIPBL

3.96e-04268172733640491
Pubmed

Mutations of the Transcriptional Corepressor ZMYM2 Cause Syndromic Urinary Tract Malformations.

TRIM33 GTF2I ATF7IP SUPT7L GMEB1

4.06e-04125172532891193
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

ZBTB33 CDK12 PTPN23 USP14 SETD2 GTF2I BAZ2A SAP30BP DOT1L SAP130

4.34e-045491721038280479
Pubmed

14-3-3 cooperates with LKB1 to regulate the activity and localization of QSK and SIK.

SNRK SIK2 CRTC2

4.37e-0430172316306228
Pubmed

Defining the NSD2 interactome: PARP1 PARylation reduces NSD2 histone methyltransferase activity and impedes chromatin binding.

ZBTB33 GTF2I BAZ2A SAP30BP

4.57e-0472172431248990
Pubmed

mSiglec-E, a novel mouse CD33-related siglec (sialic acid-binding immunoglobulin-like lectin) that recruits Src homology 2 (SH2)-domain-containing protein tyrosine phosphatases SHP-1 and SHP-2.

SIGLEC7 CD33

5.02e-047172211171044
Pubmed

Loss of KLHL6 promotes diffuse large B-cell lymphoma growth and survival by stabilizing the mRNA decay factor roquin2.

RC3H2 FBXW7

5.02e-047172229695787
Pubmed

Expression of mouse dchs1, fjx1, and fat-j suggests conservation of the planar cell polarity pathway identified in Drosophila.

FAT4 FAT2

5.02e-047172216059920
Pubmed

IL-1β-activated mTORC2 promotes accumulation of IFN-γ+ γδ T cells by upregulating CXCR3 to restrict hepatic fibrosis.

RICTOR CRTC2

5.02e-047172235361750
Pubmed

The 3' part of the immunoglobulin kappa locus of the mouse.

IGKV3D-20 IGKV3D-11

5.02e-04717229603450
Pubmed

Involvement of the Reck tumor suppressor protein in maternal and embryonic vascular remodeling in mice.

CSPG4 RECK

5.02e-047172220691046
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

CDK12 POU2F1 RICTOR RFX7 VIRMA SETD2 GTF2I BAZ2A ELF1 RIPOR1 NIPBL SON

5.03e-047741721215302935
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

FAT4 ZBTB33 CDC42BPA ACACB PPFIBP1 MUC16 RICTOR TRIM33 CNNM3 GTF2I EFNB2 ATF7IP

5.20e-047771721235844135
Pubmed

The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.

CDC42BPA PPFIBP1 KIAA1549 RICTOR FCHO2 CNNM3 LLGL2 CSPG4 NAV1 PCDH1

5.72e-045691721030639242
Pubmed

Mind bomb 1 is essential for generating functional Notch ligands to activate Notch.

EFNB2 HEY2 MAML2

5.81e-0433172316000382
Pubmed

Estrogen-regulated feedback loop limits the efficacy of estrogen receptor-targeted breast cancer therapy.

HCN1 ARHGEF12 POU2F1 TSC22D2 FHIP2A DENND4C LRCH3 TTBK2 PTPRZ1 SARDH HYDIN

6.53e-046861721129987050
Pubmed

The CREB coactivator TORC2 functions as a calcium- and cAMP-sensitive coincidence detector.

SIK2 CRTC2

6.68e-048172215454081
Pubmed

Identification of Sin1 as an essential TORC2 component required for complex formation and kinase activity.

RICTOR CRTC2

6.68e-048172217043309
Pubmed

An extracellular-matrix-specific GEF-GAP interaction regulates Rho GTPase crosstalk for 3D collagen migration.

ARHGEF7 SRGAP1

6.68e-048172225150978
Pubmed

The E3 ubiquitin ligase tripartite motif 33 is essential for cytosolic RNA-induced NLRP3 inflammasome activation.

DHX33 TRIM33

6.68e-048172225172487
Pubmed

Ubiquitylation of the ER-Shaping Protein Lunapark via the CRL3KLHL12 Ubiquitin Ligase Complex.

RICTOR LNPK

6.68e-048172232433973
Pubmed

Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.

DMTF1 HNF1A ZBTB33 POU2F1 SKIL KRBA1 GTF2I BAZ2A SCAPER GMEB1 ELF1 UTY

7.32e-048081721220412781
InteractionYWHAG interactions

RC3H2 HNF1A ZBTB33 CDC42BPA CDK12 PPFIBP1 GRB10 TNS2 RICTOR CNTLN RFX7 WNK1 VIRMA FAM13B DENND4C LRCH3 CCNF CRACD ARHGEF7 SRGAP1 SIK2 MAP3K9 NAV1 TNK2 CRTC2 OTOG SON FBXW7

1.19e-06124816628int:YWHAG
InteractionYWHAE interactions

RC3H2 HNF1A ZBTB33 CDC42BPA CDK12 PPFIBP1 GRB10 TNS2 RICTOR CNTLN WNK1 VIRMA FAM13B DENND4C LRCH3 TMEM11 CCNF CRACD ARHGEF7 SRGAP1 SIK2 MAP3K9 NAV1 DOT1L SAP130 CRTC2 OTOG FBXW7

1.35e-06125616628int:YWHAE
InteractionYWHAB interactions

RC3H2 HNF1A CDC42BPA PPFIBP1 TNS2 RICTOR CNTLN RFX7 WNK1 VIRMA DENND4C CCNF TRIM33 ARHGEF7 SRGAP1 SIK2 MAP3K9 NAV1 DOT1L SAP130 CRTC2 OTOG SON FBXW7

3.06e-06101416624int:YWHAB
InteractionTLE3 interactions

BCL9L CDK12 PROSER1 EYA3 VIRMA CCNF SETD2 MASTL DOT1L SAP130 NIPBL CRTC2 SON

1.49e-0537616613int:TLE3
Cytoband19p13.2

MBD3L5 PRR36 MBD3L2 MUC16 MBD3L3 MBD3L4 MBD3L2B

2.73e-05229172719p13.2
CytobandEnsembl 112 genes in cytogenetic band chr19p13

MBD3L5 PRR36 MBD3L2 CAPS MUC16 APBA3 MBD3L3 MBD3L4 MBD3L2B DOT1L MAP2K7

2.27e-0479717211chr19p13
GeneFamilyCD molecules|Mucins

MUC16 MUC13 MUC17 MUC3A MUC6

8.88e-08211005648
CoexpressionGSE7509_UNSTIM_VS_FCGRIIB_STIM_MONOCYTE_DN

DMTF1 CDC42BPA ACACB FCHO2 FHIP2A WNK1 PRDM10 BAZ2A SCAPER NAV1 CRTC2 SON

1.10e-0916617212M6826
CoexpressionBUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_UP

DMTF1 CLIP2 MFHAS1 GRB10 POU2F1 TSC22D2 SKIL DENND4C TRIM33 TTBK2 SETD2 PRDM10 BAZ2A ARHGEF7 ATF7IP GMEB1 MAP3K9 ELF1 RIPOR1 NIPBL

5.10e-0782217220M6782
CoexpressionGSE21063_CTRL_VS_ANTI_IGM_STIM_BCELL_NFATC1_KO_8H_UP

BCL9L CDK12 TSC22D2 SETD2 USF3 ARHGEF7 MAP2K7 NIPBL CRTC2

5.29e-061921729M8272
CoexpressionAtlasFacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_1000

COL9A1 ACACB CLIP2 PRR36 MFSD6 CEP57L1 MAMLD1 ARHGEF12 POU2F1 ZNF385B CNTLN FCHO2 WNK1 COL24A1 KRBA1 SAP30BP NAV1 ALG8 ASTN1 CEP295 SARDH MUC6 NIPBL

2.57e-0698916523Facebase_RNAseq_e10.5_Maxillary Arch_1000
CoexpressionAtlasFacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_2500_k-means-cluster#5

ZBTB33 CEP57L1 MAMLD1 ARHGEF12 POU2F1 CNTLN WNK1 TRIM33 DIP2A ARHGEF7 ALG8 ASTN1 CEP295 SARDH NIPBL SON

3.33e-0562916516Facebase_RNAseq_e10.5_Maxillary Arch_2500_K5
ToppCellLPS_IL1RA-Endothelial-Endothelial-Gen_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

FAT4 ARHGEF12 SNRK FAM13B HEG1 TNK2 NIPBL ADGRL3 SON

8.46e-082001719dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 COL9A1 FREM1 DNAH1 COL24A1 HYDIN ADGRL3 OTOG

5.85e-0718417182cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 COL9A1 FREM1 DNAH1 COL24A1 HYDIN ADGRL3 OTOG

5.85e-071841718ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 COL9A1 FREM1 DNAH1 COL24A1 HYDIN ADGRL3 OTOG

5.85e-0718417182b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellLPS-IL1RA-Endothelial-Endothelial-Artery|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL9A1 PI16 MAMLD1 F5 CRACD HEG1 EFNB2 NAV1

7.45e-071901718aed65d584ca0c25f6a8313c66b421a6618af82ea
ToppCellLPS-antiTNF-Endothelial-Endothelial-Artery|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAT4 COL9A1 PI16 MAMLD1 F5 HEG1 EFNB2 NAV1

7.75e-0719117184b3d5157344dbfbf4fab518611cd9fa37fac7bd9
ToppCellTCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6|TCGA-Prostate / Sample_Type by Project: Shred V9

ZBTB33 POU2F1 DENND4C TRIM33 USF3 BAZ2A SBF2 SON

8.38e-071931718abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligodendroglioma-3|TCGA-Brain / Sample_Type by Project: Shred V9

RC3H2 POU2F1 RICTOR RFX7 TRIM33 ATF7IP MAML2

9.32e-071351717b128596653a5e3b64ed7f657bbfeda35438e2e48
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL9A1 HCN1 FREM1 COL24A1 PTPRZ1 ASTN1 HYDIN

2.90e-061601717c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL9A1 HCN1 FREM1 COL24A1 PTPRZ1 ASTN1 HYDIN

2.90e-06160171725c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellTCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-5|TCGA-Ovary / Sample_Type by Project: Shred V9

PTPN23 POU2F1 SETD2 USF3 ATF7IP SON IMPG2

3.70e-06166171732d2eaf8a5d03881bf74d680825af2d5110b082d
ToppCellmetastatic_Brain-Endothelial_cells-Stalk-like_ECs|metastatic_Brain / Location, Cell class and cell subclass

PI16 ITGA10 GRB10 EYA3 KRBA1 HEG1 EFNB2

7.53e-061851717ad52970e88e8947ef256095bd4b40229b912d58a
ToppCelldroplet-Limb_Muscle-Pre-Sort-18m-Macroglial-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HCN1 KIAA1549 IL1RAPL1 CRACD CCDC13 HSPA12A PTPRZ1

7.53e-06185171711c147f3f5570c4761d2bcff3bad28146b4a5861
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1|TCGA-Pancreas / Sample_Type by Project: Shred V9

CDK12 ARHGEF12 TRIM33 CRACD PRDM10 CEP295 SAP130

7.80e-06186171703db813598b67b1e08f759758a1c2023396921fa
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-Artery|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL9A1 PI16 MAMLD1 F5 HEG1 EFNB2 NAV1

8.66e-061891717c45734970036e6d28d5e3fe7c9458fae38a3f624
ToppCellLPS_only-Endothelial-Endothelial-Artery|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL9A1 MUC13 F5 CRACD HEG1 EFNB2 NAV1

8.66e-061891717b028466fcd36fdeceec752e55a24286a1cd62ae4
ToppCellChildren_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)|Children_(3_yrs) / Lineage, Cell type, age group and donor

FAT4 PPFIBP1 ITGA10 ARHGEF12 IL1RAPL1 PCDH1 ADGRL3

9.27e-061911717f229abf69a1217194f74b0502486907e07dba989
ToppCellfacs-Lung-nan-3m-Endothelial-Capillary_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGEF12 SNRK HEG1 EFNB2 RIPOR1 PCDH1 ADGRL3

9.59e-0619217174bab9754cfd8b9c2d7cc1490e8a29f58c3c26f6c
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TNS2 HEG1 EFNB2 HMCN2 PTPRZ1 HEY2 IMPG2

9.92e-061931717cc355b2ed6510619cad969ae074126d7c8db784d
ToppCellfacs-Lung-nan-3m-Endothelial-endothelial_cell_of_lung|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGEF12 SNRK HEG1 EFNB2 RIPOR1 PCDH1 ADGRL3

1.03e-051941717f159ef8541d75a4e98468947f231bb463bec922c
ToppCellLPS-IL1RA-Endothelial|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAT4 ARHGEF12 SNRK HEG1 EFNB2 NAV1 ADGRL3

1.03e-05194171743f92b0533e26633dc94cce554045d641ef8fd76
ToppCellLPS-IL1RA-Endothelial-Endothelial-Gen_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAT4 ARHGEF12 GRB10 SNRK HEG1 EFNB2 ADGRL3

1.03e-0519417170b9cd96fa0b616da7cc90e92ff71157e9bba518f
ToppCellLPS-IL1RA-Endothelial-Endothelial|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAT4 ARHGEF12 SNRK HEG1 EFNB2 NAV1 ADGRL3

1.03e-0519417171d39d968730a7e85b6161c1c8a6bd38afe9bcad7
ToppCellFibroblasts-DKK3+_Fibroblasts|Fibroblasts / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

PI16 ITGA10 F5 HMCN2 PTPRZ1 HEY2 LGI1

1.10e-05196171724d64b67aa9b0e8215ad06f9101c1314b3483620
ToppCellTracheal-NucSeq|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations

LRRC37A3 RFX7 SBF2 SCAPER MAML2 UTY FBXW7

1.21e-05199171794b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-1_mon-Proliferating-Cycling_Progenitors|1_mon / Sample Type, Dataset, Time_group, and Cell type.

FAT4 KIAA1549 DHX33 CNTLN WNK1 CELSR1 NAV1

1.21e-051991717358c4b3037f59378db8916a2fbe9ed4830cf1449
ToppCellLPS_IL1RA|World / Treatment groups by lineage, cell group, cell type

CYP1B1 ARHGEF12 SKIL HEG1 SRGAP1 PCDH1 ADGRL3

1.25e-052001717a02fa5b3c4723a6eaa3c685588666c710478dd25
ToppCellControl_saline-Endothelial-Endothelial-Artery|Control_saline / Treatment groups by lineage, cell group, cell type

CYP1B1 ARSJ PI16 MAMLD1 SKIL F5 HEG1

1.25e-05200171765b71f1e8da5c3750fcd0a2e66d9ef3125a3f78a
ToppCellLPS_anti-TNF-Endothelial-Endothelial-Gen_Cap|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

FAT4 ARHGEF12 SNRK HEG1 EFNB2 TNK2 ADGRL3

1.25e-052001717a2b9d1cd291d17abddc3ee2e242121412c864b8b
ToppCellNS-control|NS / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

MFSD6 ARHGEF12 MUC16 CELSR1 FAT2 LLGL2 PTPRZ1

1.25e-052001717ecbe89ff95d046155b984c8c150e0b9e7278f839
ToppCell367C-Myeloid-Monocyte-CD16+_Monocyte|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

PI16 LRRC37A2 FAM13B CCDC13 LRRC37A PARP15

4.14e-0516417161aff83fc73b4e41e6f0d4b04dbca153bcc7a3518
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW16-Mesenchymal-Cilia-bearing_cell|GW16 / Sample Type, Dataset, Time_group, and Cell type.

LRRC37A3 CAPS RNF13 KRBA1 KCNJ13 MAP2K7

4.14e-051641716346e1530b4bf30adbcb2f7d64fdfb4cd8df69d7f
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FAT4 GRB10 TNS2 IL1RAPL1 MAML2 ADGRL3

4.90e-051691716c0824a93674e2bff0f09b2d2fab5bab016a2e379
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP1B1 FAT4 PRDM10 CSPG4 ASTN1 RECK

5.06e-05170171650c6c571591aa4b218caefe5778c570c809f567e
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP1B1 FAT4 PRDM10 CSPG4 ASTN1 RECK

5.06e-0517017168fe32dcf924d5f6665f7febbc9647d96b1e96f06
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP1B1 FAT4 PRDM10 CSPG4 ASTN1 RECK

5.06e-0517017163232db50b1a40f861e981a1b9c9073b81af9f832
ToppCellwk_20-22-Mesenchymal-Chondrocyte|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

COL9A1 ITGA10 COL24A1 PTPRZ1 CSPG4 RECK

5.23e-051711716d2938639e9a7c349e5a6ec61724222f9d127c89f
ToppCell356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

CAPS HEG1 USF3 SIK2 CEP295 MAML2

5.94e-051751716f3a68aeb79c4935006e17a5ff3445a8ec0e33f5f
ToppCellnormal_Lymph_Node-B_lymphocytes-GrB-secreting_B_cells|normal_Lymph_Node / Location, Cell class and cell subclass

LRRC37A3 DBF4B B4GALT1 COL24A1 LRRC37A PHLPP2

5.94e-05175171629fbdfe1d3bfcb063be2bced0128a33176c5b78f
ToppCellfacs-Trachea-24m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l34|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

COL9A1 ITGA10 KIAA1549 ZNF385B COL24A1 CSPG4

6.13e-05176171677c3da2eaa072a6baefb5087fd07ec18c5e271cd
ToppCellwk_15-18-Mesenchymal-Chondrocyte-ASPN+_chondrocyte|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

COL9A1 ACACB ITGA10 DNAH1 PTPRZ1 CSPG4

6.53e-051781716a55130670aa95a87b833dd3cd2de461d779e4c06
ToppCelldroplet-Heart-4Chambers-21m-Mesenchymal-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIAA1549 DNAH1 CNNM3 USF3 CSPG4 HEY2

6.73e-051791716b44e2d53b82c3c141bfc6539054b19708200a0d9
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_B-B_atypical-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

POU2F1 TECPR2 MAP3K9 FCRL5 RECK PARP15

6.73e-0517917165be883d7d0be3180bb9844e4a757f0dd247294e4
ToppCelldroplet-Liver-nan-3m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TAFA3 EFNB2 SRGAP1 HEY2 NAV1 MAML2

7.16e-051811716fcc94f04dae98b817ec06b282d2e887804d37ae5
ToppCelldroplet-Lung-30m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ARSJ KIAA1549 CCDC13 EFNB2 HEY2 HYDIN

7.61e-0518317166f8f997ffc9eaebca2683de125b6069d07c07d26
ToppCelldroplet-Limb_Muscle-nan-24m-Macroglial-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL1RAPL1 CCDC13 HSPA12A PTPRZ1 ADGRL3 LGI1

8.32e-051861716adba5647a2feaba8e361dc1020d2f2dc4ce36b16
ToppCellControl-Endothelial-Endothelial-Artery|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CYP1B1 ARSJ PI16 MAMLD1 F5 EFNB2

8.32e-0518617162d3a975d2bf92e18e3410dd413fc9f84831d82de
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

HCN1 MUC16 CNTLN SRGAP1 NAV1 ASTN1

8.32e-05186171623b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCelldroplet-Limb_Muscle-Pre-Sort-18m-Macroglial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HCN1 IL1RAPL1 CCDC13 HSPA12A PTPRZ1 ADGRL3

8.82e-051881716c2101ded71fb16b8ddbc1f883911b1ed2a533ffc
ToppCellCOVID-19-Heart-Fib_1|COVID-19 / Disease (COVID-19 only), tissue and cell type

CYP1B1 PI16 FREM1 IL1RAPL1 HMCN2 ADGRL3

8.82e-051881716fe361215f4ba841aa5e1e581fb56f2f4d3ccd201
ToppCelldroplet-Limb_Muscle-Pre-Sort-18m-Macroglial-Schwann_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HCN1 IL1RAPL1 CCDC13 HSPA12A PTPRZ1 ADGRL3

8.82e-0518817163b8b9161f0fdcbde302ce5b4c0bc874628211109
ToppCellNon-neuronal-Non-dividing-OPC-OPC|World / Primary Cells by Cluster

COL9A1 RNF13 PTPRZ1 CSPG4 TNK2 MAML2

9.09e-051891716ddf5be73912570c32c50f4ac2902da9b590526f8
ToppCellrenal_medulla_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

CDC42BPA ACACB SNRK FREM1 MAML2 UTY

9.09e-051891716830d9cd0dd706bce22eb2416f07b2c31c870a05a
ToppCellNon-neuronal-Non-dividing-OPC|World / Primary Cells by Cluster

COL9A1 RNF13 PTPRZ1 CSPG4 TNK2 MAML2

9.09e-05189171613848a031ab896b4b24c8319e4745b9b17ff9cfd
ToppCellNon-neuronal-Non-dividing-OPC-OPC-30|World / Primary Cells by Cluster

COL9A1 RNF13 PTPRZ1 CSPG4 TNK2 MAML2

9.09e-051891716313d165fad541ec6e8dd524b88856e2c93eeb681
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_anti-infl-A|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PIGN ACACB FCHO2 DNAH1 BAZ2A CD33

9.35e-05190171663018acb7ad80415e861643162abdc2e55968ee4
ToppCellFibroblasts-CD55+_Fibroblasts|Fibroblasts / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

MFSD6 CAPS ZNF385B F5 HSPA12A EFNB2

9.35e-051901716b4088128f5acf53f43244c9af9fe44e033f1a57a
ToppCellChildren_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

FAT4 PPFIBP1 ITGA10 ARHGEF12 PCDH1 ADGRL3

9.35e-0519017160e9847d7f49b2236b8a191e1a7df37556351ba9e
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC-OPC-G|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

COL9A1 PTPRZ1 CSPG4 NAV1 TNK2 ADGRL3

9.35e-0519017166c7e1086c0a274cd5527c3104106e372811c9905
ToppCellPND10|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ARHGEF12 SNRK HEG1 NAV1 ADGRL3 SON

9.35e-051901716d67e2814047c8df2ae4b7bc8be9539f5df6ecef2
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25|PBMC_fresh-frozen / Compartment, severity and other cell annotations on 10x 3' data (130k)

RICTOR SETD2 BAZ2A ARHGEF7 ELF1 PARP15

9.63e-0519117161ecd9849d14d5ebf3daf610e83fb50820cafd3ed
ToppCell356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0.5|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

DIP2A SIGLEC7 SBF2 SUPT7L PHLPP2 PARP15

9.63e-0519117162b427741a58921e161101a282d1fe526cd9e760d
ToppCellrenal_papilla_nuclei-Adult_normal_reference|renal_papilla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

CYP1B1 ACACB LRRC37A3 HEG1 NAV1 UTY

9.91e-0519217166c106b91e46eabbe686a52a65a9c94ad9cbe9390
ToppCellFibroblasts-CD55+_Fibroblasts|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

CAPS ZNF385B F5 HSPA12A EFNB2 CSPG4

1.02e-0419317168f4bf9a2fbedae35432dad96730b00c70185874c
ToppCellLPS-antiTNF-Endothelial-Endothelial|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAT4 ARHGEF12 SNRK HEG1 EFNB2 ADGRL3

1.02e-04193171602f633b016ab19bfa65bfd0cf32f000549a62148
ToppCellLPS-antiTNF-Endothelial-Endothelial-Gen_Cap|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAT4 GRB10 SNRK HEG1 EFNB2 ADGRL3

1.02e-0419317166e1982d089a9de628e6006d23ff78a223fbd9f47
ToppCellIPF-Endothelial-VE_Capillary_B|World / Disease state, Lineage and Cell class

FAT4 PPFIBP1 ITGA10 ARHGEF12 EFNB2 PCDH1

1.02e-041931716d7750a7575ef257963b7f1c64fa67c52dbff797b
ToppCellControl-Endothelial-Endothelial-Gen_Cap|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAT4 GRB10 EFNB2 SBF2 NAV1 ADGRL3

1.02e-041931716e1d546165dcc2392f540162206852c4717d7306f
ToppCellLPS-antiTNF-Endothelial|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAT4 ARHGEF12 SNRK HEG1 EFNB2 ADGRL3

1.02e-0419317165122b1ffba42de190061be34ecdc6176f84e56a3
ToppCellPND10-Endothelial-Endothelial_blood-vessel|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ARHGEF12 SNRK HEG1 EFNB2 NAV1 PCDH1

1.02e-0419317161d8acf81dcbfe81c7a73ce50c9f38fe0cbc74486
ToppCellPND10-Endothelial|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ARHGEF12 SNRK HEG1 EFNB2 NAV1 PCDH1

1.02e-041931716f3c743b340fc588bc8effd375b12e2c7cbfa49d2
ToppCelldroplet-Limb_Muscle-MUSCLE|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDK12 GRB10 SNRK FCHO2 NIPBL SON

1.05e-041941716e3d63874111d1e8da3977329426e4dcf68d6de87
ToppCellIPF-Endothelial-VE_Capillary_B|IPF / Disease state, Lineage and Cell class

PPFIBP1 ITGA10 ARHGEF12 HEG1 EFNB2 PCDH1

1.05e-041941716169a304d5c13f08c39fad4116f093bc4a0765e9d
ToppCellCOVID-19-Heart-Fib_2|Heart / Disease (COVID-19 only), tissue and cell type

CYP1B1 ARSJ PI16 HMCN2 SRGAP1 MAML2

1.05e-041941716d91c9f2ec47319051fc398320693fddbe8bbd4d6
ToppCellLPS_only-Endothelial|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAT4 SNRK HEG1 EFNB2 NAV1 ADGRL3

1.05e-04194171658f069efdefa0366033764446b9d6ffd4a17807e
ToppCellLPS_only-Endothelial-Endothelial|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAT4 SNRK HEG1 EFNB2 NAV1 ADGRL3

1.05e-041941716bfd92ec75facb0ba55c31e5f2e089d983b3d0169
ToppCell3'-Adult-Appendix-Endothelial-blood_vessel_EC-Mature_venous_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CYP1B1 DBF4B APBA3 SNRK B4GALT1 RIPOR1

1.08e-0419517166a0460d949ccda7c9fe76870d3ee6c2f60677d61
ToppCellLPS_only-Endothelial-Endothelial-Activated_Gen_Cap|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GRB10 SNRK EFNB2 NAV1 RIPOR1 ADGRL3

1.08e-04195171656efeb58df19f357d7d5ce87348d4f196a595421
ToppCellSmart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

CYP1B1 MUC16 F5 HMCN2 MUC3A LGI1

1.08e-041951716d3755929ebbbf5e3afde44281e9056ddb614a291
ToppCellSmart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

CYP1B1 MUC16 F5 HMCN2 MUC3A LGI1

1.08e-04195171619853c654ac64b3ae3bc99841c6cb29c8aaba85c
ToppCellBronchial-NucSeq|Bronchial / Cell types per location group and 10X technology with lineage, and cell group designations

LRRC37A3 ZNF385B RFX7 SCAPER MAML2 FBXW7

1.11e-041961716ab53c742866945545a92e2e61850d63c80d9a2a6
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Endothelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CDC42BPA PPFIBP1 GRB10 HEG1 EFNB2 NAV1

1.11e-0419617164cd1e6b7a791e11a40b19f971b7011bd11fe6273
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC-OPC|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

COL9A1 PTPRZ1 CSPG4 NAV1 TNK2 ADGRL3

1.11e-041961716f374cb3ec31c6eef2cef9e07547bfd1e380553af
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

COL9A1 PTPRZ1 CSPG4 NAV1 TNK2 ADGRL3

1.11e-041961716671c380b58d7f634b4fbec38c357d357ea4f3535
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

FAT4 FREM1 IL1RAPL1 COL24A1 SBF2 MAML2

1.11e-0419617161450cb69c5bf469e97c03bf1890f6f7c54165b8a
ToppCellfacs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

COL9A1 CDC42BPA ITGA10 KIAA1549 ZNF385B CSPG4

1.14e-0419717164b6c0e028b9669c102df8e9dc63e284f8d5fd9ee
ToppCellfacs-Trachea-3m-Mesenchymal-myofibroblast|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

COL9A1 CDC42BPA ITGA10 KIAA1549 ZNF385B CSPG4

1.14e-041971716ece0c17eb68f394b20e588c0b0626d3987a4dbbb
ToppCell5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.1.3|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FAT4 PPFIBP1 SNRK HEG1 EFNB2 ADGRL3

1.17e-041981716d5990cab01de6e6f3757f5a50ef70ced711bb1fa
ToppCellfacs-Trachea-nan-3m-Mesenchymal-chondrocyte|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL9A1 CDC42BPA ITGA10 KIAA1549 ZNF385B CSPG4

1.17e-04198171671e847e8c24744d6df4a960348ad2ecf310373b4
ToppCellmild-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

DMTF1 RICTOR DIP2A ATF7IP UTY PARP15

1.20e-041991716f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

COL9A1 MAMLD1 CSPG4 NAV1 TNK2 ASTN1

1.20e-041991716333056c2abe9724efeab542c0365fcfe4eff8f18
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

COL9A1 CSPG4 NAV1 TNK2 ASTN1 HYDIN

1.20e-04199171619a97e27a4758e794ce7246d295e112b47931a48
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

COL9A1 MAMLD1 CSPG4 NAV1 TNK2 ASTN1

1.20e-041991716e60ecbb8fa7bcd3e2ce7d78f6efb2cfd1fd77698
ToppCellBronchial-10x5prime-Endothelial-Endothelia_vascular-VE_systemic_arterial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CYP1B1 FAT4 CDC42BPA HEG1 EFNB2 PCDH1

1.20e-0419917166a2943a23fdd2ec814662db7c21a0d6804a6cbbc
ToppCellcontrol|World / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

MFSD6 ARHGEF12 CELSR1 FAT2 LLGL2 PTPRZ1

1.24e-04200171697f36d2c197e03d93a1fc59949d77ae90f6e6a9a
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial-Artery|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

PI16 MAMLD1 SKIL F5 HEG1 EFNB2

1.24e-04200171677ae679c35d3b9e2b620f34129f3a8d47e922c65
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW13-Mesenchymal-Mesoderm|GW13 / Sample Type, Dataset, Time_group, and Cell type.

ACACB LRRC37A2 RFX7 B4GALT1 LLGL2 PCDH1

1.24e-0420017160f4b8b0868bda406fe6bf01d1b722510fdfd0168
ToppCellLPS_IL1RA-Endothelial-Endothelial-Artery|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

FAT4 PI16 MAMLD1 F5 HEG1 EFNB2

1.24e-042001716ac9ead34afa14067171833f5c277eaf06db7b02e
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

COL9A1 MAMLD1 CSPG4 NAV1 TNK2 ASTN1

1.24e-042001716ad777683adeb2ce45ade570386235e311fa7ea2d
ToppCellBrain_organoid-organoid_Tanaka_cellReport-6m-Mesenchymal-Cilia-bearing_cell|6m / Sample Type, Dataset, Time_group, and Cell type.

CAPS F5 CCDC13 KCNJ13 HYDIN PDE11A

1.24e-042001716177f9ad8dd8635394c575a2b30140184df0bd51e
DrugStrophantine octahydrate [11018-89-6]; Up 200; 5.4uM; HL60; HT_HG-U133A

GRB10 POU2F1 TSC22D2 SKIL EFNB2 ATF7IP NIPBL SON FBXW7

6.04e-0617416891302_UP
DrugKetoconazole [65277-42-1]; Up 200; 7.6uM; PC3; HT_HG-U133A

ZBTB33 CDC42BPA MFHAS1 SNRK B4GALT1 TRIM33 KCNJ13 GMEB1 MAP2K7

1.45e-0519416894624_UP
DrugFusaric acid [536-69-6]; Up 200; 22.4uM; MCF7; HT_HG-U133A

CDC42BPA PRR36 B4GALT1 BAZ2A SCAPER MAP2K7 PCDH1 UTY IMPG2

1.45e-0519416893245_UP
DrugMenadione [58-27-5]; Down 200; 23.2uM; PC3; HT_HG-U133A

ACACB MAMLD1 SNRK TTBK2 DIP2A GTF2I SUPT7L BICRAL NIPBL

1.45e-0519416894662_DN
DrugMethionine sulfoximine (L) [15985-39-4]; Down 200; 22.2uM; HL60; HT_HG-U133A

ACACB CNTLN F5 CHMP7 CNNM3 CELSR1 BAZ2A UTY ADGRL3

1.51e-0519516892470_DN
DrugTiaprofenic acid [33005-95-7]; Down 200; 15.4uM; PC3; HT_HG-U133A

ARSJ CDC42BPA MFSD6 EYA3 TECPR2 ARHGEF7 RIPOR1 RECK FBXW7

1.64e-0519716894091_DN
DrugMilrinone [78415-72-2]; Up 200; 19uM; MCF7; HT_HG-U133A

WNK1 F5 TTBK2 SIGLEC7 KCNJ13 SCAPER SIK2 SLC24A1 MAP2K7

1.70e-0519816897210_UP
DrugBAS 012416453; Down 200; 38uM; MCF7; HT_HG-U133A

CYP1B1 DBF4B GRB10 TSC22D2 BFSP1 GMEB1 HEY2 TNK2 SLC24A1

1.70e-0519816896880_DN
DrugLanatoside C [17575-22-3]; Up 200; 4uM; MCF7; HT_HG-U133A

CYP1B1 POU2F1 TSC22D2 SKIL EFNB2 BAZ2A ATF7IP SON

3.06e-0516416883852_UP
Drugirinotecan HCl; Down 200; 100uM; MCF7; HT_HG-U133A

CDK12 TRIM33 SETD2 ARHGEF7 ATF7IP ELF1 SAP130 NIPBL

6.65e-0518316887498_DN
DrugCamptothecine (S,+) [7689-03-4]; Down 200; 11.4uM; MCF7; HT_HG-U133A

TSC22D2 CCNF TRIM33 EFNB2 ATF7IP ELF1 NIPBL PHLPP2

6.91e-0518416882321_DN
DrugGSK-3beta Inhibitor VIII; Up 200; 10uM; PC3; HT_HG-U133A

RC3H2 ARHGEF12 GRB10 WNK1 SETD2 MAP3K9 ELF1 SON

8.65e-0519016887070_UP
DrugMeticrane [1084-65-7]; Up 200; 14.6uM; PC3; HT_HG-U133A

FAT4 CDC42BPA ACACB MFSD6 ARHGEF12 RFX7 BFSP1 SETD2

9.31e-0519216881792_UP
DrugMefloquine hydrochloride [51773-92-3]; Up 200; 9.6uM; HL60; HG-U133A

ARHGEF12 TSC22D2 SKIL TTBK2 SETD2 BAZ2A SCAPER SIK2

1.00e-0419416881364_UP
DrugCyproterone acetate [427-51-0]; Down 200; 9.6uM; PC3; HT_HG-U133A

CYP1B1 DBF4B SNRK SKIL WNK1 TRIM33 BAZ2A SCAPER

1.00e-0419416884470_DN
DrugBenfotiamine [22457-89-2]; Down 200; 8.6uM; PC3; HT_HG-U133A

RC3H2 CDC42BPA DBF4B SKIL WNK1 EFNB2 ELF1 SLC24A1

1.00e-0419416884312_DN
DrugHydrocortisone base [50-23-7]; Up 200; 11uM; MCF7; HT_HG-U133A

PIGN FAT4 CDC42BPA ACACB SKIL TECPR2 TNK2 PCDH1

1.00e-0419416883284_UP
Drugprochlorperazine dimaleate salt; Up 200; 10uM; HL60; HT_HG-U133A

CYP1B1 ACACB SKIL F5 B4GALT1 PRDM10 SIGLEC7 ARHGEF7

1.04e-0419516881156_UP
DrugIndomethacin [53-86-1]; Up 200; 11.2uM; MCF7; HT_HG-U133A

CYP1B1 GRB10 TSC22D2 HSPA12A BAZ2A SCAPER RIPOR1 PDE11A

1.07e-0419616887409_UP
DrugImipramine hydrochloride [113-52-0]; Up 200; 12.6uM; HL60; HT_HG-U133A

CDC42BPA ACACB APBA3 TNS2 TRIM33 SIGLEC7 SUPT7L TNK2

1.07e-0419616881849_UP
DrugPiribedil hydrochloride [78213-63-5]; Up 200; 12uM; HL60; HT_HG-U133A

CLIP2 WNK1 TRIM33 CELSR1 HEG1 SIGLEC7 SCAPER TNK2

1.07e-0419616882951_UP
Drugalpha-estradiol; Up 200; 0.01uM; HL60; HT_HG-U133A

CDC42BPA ACACB MFSD6 EYA3 F5 HEG1 TNK2 ASTN1

1.07e-0419616886169_UP
DrugMiconazole [22916-47-8]; Up 200; 9.6uM; HL60; HG-U133A

CDK12 MPDU1 SNRK TSC22D2 TRIM33 ARHGEF7 DNASE1L1 RECK

1.11e-0419716881977_UP
DrugEsculin Hydrate [531-75-9]; Up 200; 11.8uM; MCF7; HT_HG-U133A

HNF1A CDC42BPA ACACB SIGLEC7 TNK2 SLC24A1 MAP2K7 RECK

1.11e-0419716883390_UP
DrugPhenformin hydrochloride [834-28-6]; Down 200; 16.6uM; HL60; HT_HG-U133A

RC3H2 DBF4B MPDU1 SRR SCAPER GMEB1 MAP2K7 UTY

1.11e-0419716882350_DN
DrugIfosfamide [3778-73-2]; Up 200; 15.4uM; MCF7; HT_HG-U133A

PIGN MFHAS1 PPFIBP1 SRR WNK1 DIP2A SUPT7L HEY2

1.11e-0419716883485_UP
DrugAtropine sulfate monohydrate [5908-99-6]; Down 200; 5.8uM; PC3; HT_HG-U133A

CYP1B1 RC3H2 ACACB ARHGEF12 CHMP7 BAZ2A RIPOR1 RECK

1.11e-0419716885865_DN
DrugTerbutaline hemisulfate [23031-32-5]; Down 200; 7.2uM; MCF7; HT_HG-U133A

ACACB PRR36 ITGA10 TMEM104 TTBK2 SUPT7L SCAPER SIK2

1.11e-0419716883202_DN
DrugDeferoxamine mesylate [138-14-7]; Up 200; 6uM; MCF7; HT_HG-U133A

HNF1A CDC42BPA TNS2 MUC13 TSC22D2 SCAPER TNK2 IMPG2

1.15e-0419816883842_UP
DrugPiretanide [55837-27-9]; Down 200; 11uM; HL60; HT_HG-U133A

CLIP2 TNS2 EYA3 SKIL LLGL2 ARHGEF7 RIPOR1 ADGRL3

1.15e-0419816886144_DN
DrugPhthalylsulfathiazole [85-73-4]; Up 200; 10uM; MCF7; HT_HG-U133A

ACACB PRR36 ARHGEF12 PRDM10 SIGLEC7 MAP2K7 PCDH1 PHLPP2

1.15e-0419816885614_UP
DrugMetaproterenol sulfate, orciprenaline sulfate [5874-97-5]; Up 200; 7.6uM; MCF7; HT_HG-U133A

ZBTB33 ACACB ARHGEF12 SIGLEC7 BAZ2A MAP3K9 HEY2 SLC24A1

1.15e-0419816882845_UP
DrugChicago sky blue 6B [2610-05-1]; Up 200; 4uM; HL60; HT_HG-U133A

RC3H2 SNRK SRR SKIL LRCH3 RIPOR1 UTY DNASE1L1

1.15e-0419816881330_UP
DrugPhentolamine hydrochloride [73-05-2]; Down 200; 12.6uM; HL60; HT_HG-U133A

RC3H2 DBF4B SKIL TRIM33 TTBK2 BAZ2A NIPBL PHLPP2

1.15e-0419816882362_DN
DrugGabexate mesilate [56974-61-9]; Up 200; 9.6uM; MCF7; HT_HG-U133A

PRR36 APBA3 SIK2 RIPOR1 MUC6 UTY PDE11A FBXW7

1.15e-0419816887357_UP
DrugClindamycin hydrochloride [21462-39-5]; Up 200; 8.6uM; MCF7; HT_HG-U133A

GRB10 SNRK TSC22D2 SCAPER GMEB1 SIK2 MAP2K7 MUC6

1.19e-0419916887172_UP
DrugNalidixic acid sodium salt hydrate; Down 200; 14.6uM; MCF7; HT_HG-U133A

PRR36 EYA3 BFSP1 HSPA12A TECPR2 BAZ2A SCAPER FBXW7

1.19e-0419916884691_DN
Drugtamoxifen citrate; Down 200; 1uM; MCF7; HG-U133A

PPFIBP1 ARHGEF12 TSC22D2 WNK1 DENND4C CCNF BAZ2A UTY

1.19e-041991688380_DN
DrugDioxybenzone [131-53-3]; Up 200; 16.4uM; PC3; HT_HG-U133A

RC3H2 SNRK HSPA12A HEG1 CSPG4 PCDH1 MUC6 PDE11A

1.23e-0420016884638_UP
Diseaseazoospermia (implicated_via_orthology)

CDC42BPA DMRT2 SCAPER

4.31e-04271623DOID:14227 (implicated_via_orthology)
Diseasevaricose veins (is_marker_for)

EFNB2 HEY2

4.43e-0461622DOID:799 (is_marker_for)
Diseaseuric acid measurement

PIGN HNF1A FAT4 CDC42BPA GRB10 F5 B4GALT1 TMEM11 SBF2 SIK2 NAV1

5.79e-0461016211EFO_0004761
Diseasesmoking status measurement, high density lipoprotein cholesterol measurement

EYA3 PTPRZ1

6.18e-0471622EFO_0004612, EFO_0006527
Diseasesevere acute respiratory syndrome, COVID-19

MAMLD1 GRB10 TG IL1RAPL1 COL24A1 HSPA12A ARHGEF7 MAML2 ADGRL3

8.53e-044471629EFO_0000694, MONDO_0100096
DiseaseAdenocarcinoma of lung (disorder)

PIGN SRR WNK1 TRIM33 TNK2 DOT1L

9.98e-042061626C0152013
DiseaseDisorder of eye

CYP1B1 COL9A1 FREM1 KCNJ13 SLC24A1 IMPG2

1.16e-032121626C0015397
DiseaseCongenital disorder of glycosylation

MPDU1 B4GALT1 ALG8

1.19e-03381623cv:C0282577
DiseaseCystic Kidney Diseases

FAT4 ALG8

1.59e-03111622C1691228
Diseaseschizophrenia, type 2 diabetes mellitus

HNF1A CDK12 HCN1

1.71e-03431623MONDO_0005090, MONDO_0005148
Diseaseoptic disc area measurement

ARSJ CDC42BPA F5

1.95e-03451623EFO_0006937
Diseaseheart rate variability measurement, response to antipsychotic drug

RICTOR SKIL SAP130

2.07e-03461623EFO_0008003, GO_0097332
DiseaseT-cell surface glycoprotein CD3 epsilon chain measurement

F5 PIKFYVE

2.25e-03131622EFO_0802114
Diseasebeta-amyloid 1-42 measurement, cerebrospinal fluid biomarker measurement

FAT4 LGI1

2.61e-03141622EFO_0004670, EFO_0006794
DiseaseWilliams-Beuren syndrome (implicated_via_orthology)

CLIP2 GTF2I

3.00e-03151622DOID:1928 (implicated_via_orthology)
Diseasemyeloid cell surface antigen CD33 measurement

SIGLEC7 CD33

3.00e-03151622EFO_0008238
Diseasered blood cell density measurement

HNF1A ARSJ CDK12 RICTOR FCHO2 RFX7 WNK1 B4GALT1 TG TRIM33 SBF2 MAML2

3.50e-0388016212EFO_0007978
Diseaseautosomal dominant intellectual developmental disorder (is_implicated_in)

RFX7 SETD2

3.86e-03171622DOID:0060307 (is_implicated_in)
Diseasechronic lymphocytic leukemia

ARSJ RFX7 FREM1 KPNA7

4.26e-031191624EFO_0000095
Diseasecholangiocarcinoma (is_marker_for)

MUC16 MUC3A MUC6

5.30e-03641623DOID:4947 (is_marker_for)

Protein segments in the cluster

PeptideGeneStartEntry
TEVPSILAAHSLPSL

PI16

286

Q6UXB8
ASNLTSVPVPHTTAL

B4GALT1

111

P15291
HSSISPVRLPLNSSL

CDK12

381

Q9NYV4
SSQLVAHPPGTVITS

ELF1

541

P32519
HLPLATVSPGTTQLT

CAPS

51

Q13938
LQTPAETLLSDSIPH

CSPG4

96

Q6UVK1
AQVPHRPSLSSLETL

CNTLN

446

Q9NXG0
SSTIQLHPATSPAVS

BAZ2A

416

Q9UIF9
ELALSPIHNSSALPT

MASTL

366

Q96GX5
IGNITLSPAISRHSP

FCHO2

381

Q0JRZ9
NPPLSSQATVHITVT

FAT4

3066

Q6V0I7
TTHLPSASSQIPALE

ADGRL3

481

Q9HAR2
TSVTLSIVHCPPVTT

APBA3

471

O96018
LHSGTATPPLTSRVI

CLIP2

171

Q9UDT6
QPPQHLVTTILLSAS

ARHGEF7

91

Q14155
LSSTTVLFRPIHPIN

CELSR1

1331

Q9NYQ6
ATVGSRSSTPQHPLL

DOT1L

976

Q8TEK3
LPLTLTASPTVTLTA

DMTF1

521

Q9Y222
SVLPLTTLTDPILQH

DMTF1

716

Q9Y222
QPVLRLSTVHEPSST

ASTN1

1031

O14525
LLSVELSTSRPPQHL

TNK2

496

Q07912
QSLVGSPSTRIAPHI

ARHGEF12

336

Q9NZN5
HTQKAPLVSSTLPVA

RC3H2

786

Q9HBD1
DSPTLASHVPLSALI

RECK

916

O95980
SGLIQTPSPSQHSVL

EYA3

131

Q99504
TTTVDSIQAPIPSHT

PTPN23

881

Q9H3S7
ATSPLTTVHTTPILT

KIAA1549

786

Q9HCM3
EIVLTQSPATLSLSP

IGKV3D-11

21

A0A0A0MRZ8
TVPISITNPDLLRHS

ACACB

1336

O00763
PPLSTSLLSLSATVH

HEY2

251

Q9UBP5
SLVPIHATTSPSNIL

MUC16

4161

Q8WXI7
SPLPVTALLTSVLVT

MUC16

5656

Q8WXI7
SPPNLSSTSHEILTT

MUC16

6856

Q8WXI7
TVSLVTHPAQTSPTV

MUC16

10821

Q8WXI7
TTLPTHVPPFSTSLV

MUC6

1441

Q6W4X9
TLPTHVPPFSTSLVT

MUC6

1611

Q6W4X9
PITTQLPHLSSATTP

MUC6

2106

Q6W4X9
TLPHTISSPFTLSAL

MUC6

2211

Q6W4X9
LVESVVQTPSTLHLP

OR2H2

151

O95918
SSSTRPITSPLQEVH

PARP15

231

Q460N3
TSNAIPHLLALISPT

KPNA7

196

A9QM74
QTLHRSLTEVTGPPT

LRRC37A3

781

O60309
APTRSLHLVSPQVFT

KRBA1

561

A5PL33
RPNALLSSPATETVH

LRCH3

576

Q96II8
APSATQITVVLPHSS

LLGL2

126

Q6P1M3
QTLHRSLTEVTGPPT

LRRC37A2

781

A6NM11
QTLHRSLTEVTGPPT

LRRC37A

781

A6NMS7
EIVLTQSPATLSLSP

IGKV3D-20

21

A0A0C4DH25
TPQGTVLLHTPATSE

SLC24A1

306

O60721
TLSQGSSPVTVHTLP

GMEB1

426

Q9Y692
LQPDTLSIASHASLP

MFHAS1

936

Q9Y4C4
KLLVSSAPTHLTPNI

ZBTB33

266

Q86T24
TPLHDSLPITGTSVA

SBF2

186

Q86WG5
HTTILQVSIPSLLPA

PPFIBP1

401

Q86W92
PLTNITAALHSPLTL

HMCN2

2366

Q8NDA2
LEPSTTSTSQPHLIF

ARSJ

66

Q5FYB0
TTHSSVLIITPRPQD

CD33

191

P20138
IPTVHTSPQLINTTA

KIAA2026

1976

Q5HYC2
ATSTHISPISILPAS

FAM13B

281

Q9NYF5
SLLPVLKSSHQTPTL

FAM90A27P

206

A6NNH2
SSPLHLESVLSILAP

MBD3L5

106

A6NJ08
PQHTTTLSLSTLATP

EFNB2

261

P52799
SGIPPLSSLTSVRVH

FAT2

3506

Q9NYQ8
LSVTVPVSHPVLNLS

FCRL5

371

Q96RD9
VTVPVSHPVLTLSSA

FCRL5

466

Q96RD9
HTNSAILPLLPRETS

IL1RAPL1

676

Q9NZN1
TESPRTSGVLSQPHL

MAP2K7

401

O14733
TAPSNTSHKLLTPQT

PCDH1

716

Q08174
SPHDTLISETLLNSP

MUC3A

81

Q02505
PTSFIITISHPTSIC

MUC3A

131

Q02505
HTQSISSPPAITSTL

MUC3A

1676

Q02505
SIPTDISTLPTRTHI

MUC3A

2511

Q02505
ASSLPPTTAHILSAL

PDE11A

161

Q9HCR9
LSVTPQRTTGALHTP

DDIAS

461

Q8IXT1
TAPRITLLHSPSQVG

FREM1

1626

Q5H8C1
SSPLHLESVLSILAP

MBD3L2B

106

A0A1B0GVZ6
PHVPITTLAGIASLT

NIPBL

6

Q6KC79
SITPSSPLATLLQHE

KCNJ13

246

O60928
SHITTANLPPQISSI

EP400P1

246

Q6ZTU2
LVTVSTPLHQVSPTG

HNF1A

341

P20823
LSLTHPEILVPQIST

HEG1

881

Q9ULI3
TGITPLSPSHIVNDT

HSPA12A

31

O43301
TIHTPLTTAVISATP

PRDM10

866

Q9NQV6
ISLTSQTVTELPPHT

PTPRZ1

516

P23471
LITPTASLLQPTHAL

PTPRZ1

976

P23471
TTHPTNASHQLTILP

MFSD6

166

Q6ZSS7
HLSLSKSNSVSLVPP

RICTOR

1276

Q6R327
SSPLHLESVLSILAP

MBD3L3

106

A6NE82
LTVSPVLPLTSAAVT

POU2F1

476

P14859
DLHISSTPAATTLPV

PROSER1

591

Q86XN7
ALANPVSTHTILTPN

MAML2

831

Q8IZL2
THLPTPSSTLQEQLT

NPAS4

446

Q8IUM7
IHPDSSNTPLSTRLV

PIKFYVE

276

Q9Y2I7
ATITSQLLPTPAKSH

DNAH1

2421

Q9P2D7
VSLPISVHTQTFLPS

ATMIN

451

O43313
LSASQPSLPHEVSTL

HCN1

786

O60741
ISPSSTIHIPLVLET

HYDIN

756

Q4G0P3
PTVLHLSPGQSSVSQ

BICRAL

506

Q6AI39
VSRPVLSPTHINATA

CCDC150

11

Q8NCX0
SNVLPSLVLVPLHTT

DNASE1L1

136

P49184
SLVLPHTPEIQTTRS

DMRT2

401

Q9Y5R5
LPQPTSVLSLDSDSH

CCNF

721

P41002
SHTCVSATTLLPALP

DBF4B

421

Q8NFT6
PLSSHPVVALSELST

CHMP7

171

Q8WUX9
SLPASSLARHVLPTT

CRTC2

371

Q53ET0
LTCLNSITHLPLTTV

SLC49A4

366

Q96SL1
QQIIHTTPPASIVTS

BFSP1

191

Q12934
PSSLSVPHTAILVTG

CRACD

586

Q6ZU35
HTLVESALTRPSLPS

CCDC13

511

Q8IYE1
SSSIVDLPVHQLSSP

FBXW7

146

Q969H0
TLSQVHSPLVTSPSA

BCL9L

936

Q86UU0
VSLLSVDSVLHNPPS

DHX33

526

Q9H6R0
SVHDALILSQPVSTP

DENND4C

371

Q5VZ89
PTAHSIVQATRTSLP

ATF7IP

876

Q6VMQ6
TIHLLPTAPTTVNVT

ATF7IP

1026

Q6VMQ6
EPLVLDHPQATLSTT

MAMLD1

206

Q13495
STSPVVPASLHGLLS

IFRD2

286

Q12894
SSRPIVHLTPSLEVT

ITGA10

641

O75578
VHLTPSLEVTPQAIS

ITGA10

646

O75578
ILGSQSPLHPSTLST

GRB10

471

Q13322
EIVLTQSPATLSLSP

IGKV3-11

21

P04433
HIPLTSIDLCPTSVS

KRTAP26-1

21

Q6PEX3
VTSPKILHSPNSQAL

CEP57L1

41

Q8IYX8
TCHELPARITPSQTT

COL9A1

251

P20849
PVTIPHATTANTSVL

CYP1B1

396

Q16678
RLTSTPLQSHSSVEP

DIP2A

151

Q14689
QVTSVLSRLSLFPHP

FHIP2A

656

Q5W0V3
PELLTHSTTEVTQPR

GTF2I

541

P78347
TLPITTVAQSSVLLH

CEP295

481

Q9C0D2
HVIPSPSTDRINVTS

SCAPER

181

Q9BY12
DPNQSLTPTHVTLTT

MAP3K9

891

P80192
SSPLHLESVLSILAP

MBD3L4

106

A6NDZ8
SSPLHLESVLSILAP

MBD3L2

106

Q8NHZ7
VTASLLAIPHTPESS

OTOG

1566

Q6ZRI0
EGTTPLTSIPVSHTL

MUC17

2276

Q685J3
PVAVTSPITHTAQSA

NAV1

536

Q8NEY1
HLTLAALQPPTATVL

TAFA3

26

Q7Z5A8
DLPLASHRSTSQILP

UTY

816

O14607
LLTALPNHSSSPETT

TRMT13

466

Q9NUP7
ESSLTPPLSTNLHLE

TRIM33

811

Q9UPN9
PAVINAHVSTISLPT

PRSS3P2

116

Q8NHM4
TPATSTESLSPLHNV

SRGAP1

1001

Q7Z6B7
RSLATVHPDSSNLIP

SFXN4

91

Q6P4A7
RTCTSVPETLHLNPS

SKIL

71

P12757
PVSRSSSIIQHVGLP

TSC22D2

546

O75157
QTNLSPDLSHTTLSP

F5

1201

P12259
PDLSHTTLSPELIQR

F5

1206

P12259
TPHSSSLTCQLATPL

PRR36

356

Q9H6K5
SPLTIHPLQALSSLA

PRR36

681

Q9H6K5
TEHTPLLRPLASVSA

RNF13

306

O43567
FSHIQTPVVSSTPRL

MRPL35

46

Q9NZE8
PLHPSTTRSSVLTLI

SIGLEC7

191

Q9Y286
TTRSSVLTLIPQPQH

SIGLEC7

196

Q9Y286
ESVSTLPASVHPQLS

SIK2

656

Q9H0K1
PSEPCSLTIHTIQLI

SUPT7L

56

O94864
DSIHLTPVLTSSILN

SRR

21

Q9GZT4
VSSLTLHSVTPAVLQ

IMPG2

481

Q9BZV3
RTVDSTPLSVHTPTL

CDC42BPA

981

Q5VT25
DLTATPLSHATVPQS

SNRK

376

Q9NRH2
SPLTPLTVVTLLQAS

MPDU1

146

O75352
STSSTHTPLPVFRLL

SLC23A3

251

Q6PIS1
LTVSRLAPSHQASPL

SARDH

621

Q9UL12
HTVLPSVTPLATLIC

ALG8

326

Q9BVK2
TVPSSVHQSPVSSLQ

CNNM3

591

Q8NE01
SASTPLPQGVHLTES

COL24A1

66

Q17RW2
VLLPHPLRSTESTNA

TEX22

111

C9J3V5
LPLHTLTSSTPVVLV

TMEM11

146

P17152
APPIISTHSSSTIPI

MUC13

86

Q9H3R2
PHISSTPLTIQDELL

PHLPP2

966

Q6ZVD8
AVSHLRLLPTANSPS

ST20-AS1

21

Q8NBB2
VTTRITLPSHPALGT

SAP130

341

Q9H0E3
TSTTPQLHTRLTPAA

TTBK2

311

Q6IQ55
CQHSLPSLITPVSSK

TMEM104

286

Q8NE00
PHILVSQVPGLSSTT

USF3

951

Q68DE3
EVPLLNSLTVPSSLS

TECPR2

641

O15040
ISLTPSNSNTPLKHS

RFX7

381

Q2KHR2
STCHTTTLPALVRTP

ZNF385B

86

Q569K4
TLASSLVVPLLSSPV

PIGN

691

O95427
IAQPTILTTTATLPA

SAP30BP

266

Q9UHR5
LLATTTAVASPPTHA

SETD2

156

Q9BYW2
PHLLTIQPDLSTTTT

UNC5A

361

Q6ZN44
VSQIPISTPHVSTAQ

WNK1

841

Q9H4A3
TSSSIPPIILLQFLH

USP14

166

P54578
TSPTHPTTSPILINV

RIPOR1

666

Q6ZS17
ASVPSVPISTHGRLL

TG

2196

P01266
TLLLSIPVTSAHPGV

VIRMA

686

Q69YN4
STSLLVPAVTTPVLA

SON

1326

P18583
SALVSQHSISPISLP

TNS2

1226

Q63HR2
TVTPALSSNVLPRHL

LNPK

211

Q9C0E8
PQTLRTPHLILSSSS

LGI1

391

O95970
TPHLILSSSSQRPVI

LGI1

396

O95970