Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	aspartic-type endopeptidase activity	ERVK-18 ERVK-8 ERVK-6 ERVK-19 ERVK-7 ERVK-21 ERVK-25 ERVK-24	4.55e-15	37	40	8	GO:0004190
GeneOntologyMolecularFunction	aspartic-type peptidase activity	ERVK-18 ERVK-8 ERVK-6 ERVK-19 ERVK-7 ERVK-21 ERVK-25 ERVK-24	5.76e-15	38	40	8	GO:0070001
GeneOntologyMolecularFunction	endopeptidase activity	ERVK-18 ERVK-8 PCSK5 ERVK-6 ERVK-19 ERVK-7 ERVK-21 ERVK-25 ERVK-24 LPA	9.19e-09	430	40	10	GO:0004175
GeneOntologyMolecularFunction	peptidase activity	ERVK-18 ERVK-8 PCSK5 ERVK-6 ERVK-19 ERVK-7 ERVK-21 ERVK-25 ERVK-24 LPA	4.62e-07	654	40	10	GO:0008233
GeneOntologyMolecularFunction	structural molecule activity	ERVK-18 ERVK-8 ERVK-5 ERVK-6 ERVK-19 ERVK-7 ERVK-21 ERVK-25 EFEMP1 HMCN2 ERVK-24	9.24e-07	891	40	11	GO:0005198
GeneOntologyMolecularFunction	RNA-DNA hybrid ribonuclease activity	ERVK-8 ERVK-6 ERVK-7	1.22e-06	11	40	3	GO:0004523
GeneOntologyMolecularFunction	RNA-directed DNA polymerase activity	ERVK-8 ERVK-6 ERVK-7	2.67e-06	14	40	3	GO:0003964
GeneOntologyMolecularFunction	RNA stem-loop binding	ERVK-8 ERVK-6 ERVK-7	9.66e-06	21	40	3	GO:0035613
GeneOntologyMolecularFunction	zinc ion binding	ERVK-8 ERVK-5 ERVK-6 ERVK-19 ERVK-7 CAD ERVK-21 ERVK-24 BRCA1	5.28e-05	891	40	9	GO:0008270
GeneOntologyMolecularFunction	RNA endonuclease activity, producing 5'-phosphomonoesters	ERVK-8 ERVK-6 ERVK-7	5.52e-05	37	40	3	GO:0016891
GeneOntologyMolecularFunction	DNA polymerase activity	ERVK-8 ERVK-6 ERVK-7	5.98e-05	38	40	3	GO:0034061
GeneOntologyMolecularFunction	transition metal ion binding	ERVK-8 ERVK-5 ERVK-6 ERVK-19 ERVK-7 CAD ERVK-21 ERVK-24 BRCA1 HEPH	8.85e-05	1189	40	10	GO:0046914
GeneOntologyMolecularFunction	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	ERVK-8 ERVK-6 ERVK-7	1.06e-04	46	40	3	GO:0016893
GeneOntologyMolecularFunction	nucleotidyltransferase activity	ERVK-8 ERVK-6 ERVK-7 PARP15	2.38e-04	152	40	4	GO:0016779
GeneOntologyMolecularFunction	prostaglandin transmembrane transporter activity	SLCO1B3 SLCO1B1	3.51e-04	14	40	2	GO:0015132
GeneOntologyMolecularFunction	icosanoid transmembrane transporter activity	SLCO1B3 SLCO1B1	4.04e-04	15	40	2	GO:0071714
GeneOntologyMolecularFunction	oligopeptide transmembrane transporter activity	SLCO1B3 SLCO1B1	4.61e-04	16	40	2	GO:0035673
GeneOntologyMolecularFunction	transferase activity, transferring phosphorus-containing groups	ERVK-8 ERVK-6 TLK1 ERVK-7 CAD EFEMP1 ROR1 PARP15	4.63e-04	938	40	8	GO:0016772
GeneOntologyMolecularFunction	RNA endonuclease activity	ERVK-8 ERVK-6 ERVK-7	5.30e-04	79	40	3	GO:0004521
GeneOntologyMolecularFunction	sodium-independent organic anion transmembrane transporter activity	SLCO1B3 SLCO1B1	5.87e-04	18	40	2	GO:0015347
GeneOntologyMolecularFunction	bile acid transmembrane transporter activity	SLCO1B3 SLCO1B1	2.11e-03	34	40	2	GO:0015125
GeneOntologyMolecularFunction	RNA nuclease activity	ERVK-8 ERVK-6 ERVK-7	2.54e-03	136	40	3	GO:0004540
GeneOntologyMolecularFunction	endonuclease activity	ERVK-8 ERVK-6 ERVK-7	2.54e-03	136	40	3	GO:0004519
GeneOntologyMolecularFunction	amide transmembrane transporter activity	SLCO1B3 SLCO1B1	3.20e-03	42	40	2	GO:0042887
GeneOntologyMolecularFunction	transmembrane receptor protein tyrosine kinase activity	EFEMP1 ROR1	7.52e-03	65	40	2	GO:0004714
GeneOntologyMolecularFunction	organic hydroxy compound transmembrane transporter activity	SLCO1B3 SLCO1B1	8.67e-03	70	40	2	GO:1901618
GeneOntologyBiologicalProcess	DNA integration	ERVK-8 ERVK-6 ERVK-7	1.91e-06	13	40	3	GO:0015074
GeneOntologyBiologicalProcess	viral process	ERVK-8 PCSK5 ERVK-5 ERVK-6 ERVK-19 ERVK-7 ERVK-21 ERVK-24	2.52e-06	464	40	8	GO:0016032
GeneOntologyBiologicalProcess	cell-cell fusion	ERVK-8 ERVK-6 ERVK-19 ERVK-21	2.19e-05	85	40	4	GO:0140253
GeneOntologyBiologicalProcess	syncytium formation by plasma membrane fusion	ERVK-8 ERVK-6 ERVK-19 ERVK-21	2.19e-05	85	40	4	GO:0000768
GeneOntologyBiologicalProcess	syncytium formation	ERVK-8 ERVK-6 ERVK-19 ERVK-21	2.63e-05	89	40	4	GO:0006949
GeneOntologyBiologicalProcess	Tie signaling pathway	ANGPT1 SVEP1	3.65e-05	5	40	2	GO:0048014
GeneOntologyBiologicalProcess	DNA synthesis involved in DNA repair	ERVK-8 ERVK-6 ERVK-7	1.10e-04	48	40	3	GO:0000731
GeneOntologyBiologicalProcess	pigment catabolic process	SLCO1B3 SLCO1B1	1.99e-04	11	40	2	GO:0046149
GeneOntologyBiologicalProcess	heme catabolic process	SLCO1B3 SLCO1B1	1.99e-04	11	40	2	GO:0042167
GeneOntologyBiologicalProcess	porphyrin-containing compound catabolic process	SLCO1B3 SLCO1B1	2.82e-04	13	40	2	GO:0006787
GeneOntologyBiologicalProcess	tetrapyrrole catabolic process	SLCO1B3 SLCO1B1	3.29e-04	14	40	2	GO:0033015
GeneOntologyBiologicalProcess	sodium-independent organic anion transport	SLCO1B3 SLCO1B1	3.79e-04	15	40	2	GO:0043252
GeneOntologyBiologicalProcess	DNA-templated DNA replication	ERVK-8 ERVK-6 ERVK-7 BRCA1	3.84e-04	178	40	4	GO:0006261
GeneOntologyBiologicalProcess	RNA-templated DNA biosynthetic process	ERVK-8 ERVK-6 ERVK-7	5.58e-04	83	40	3	GO:0006278
HumanPheno	Bilirubinuria	SLCO1B3 SLCO1B1	5.09e-06	2	12	2	HP:0031811
MousePheno	abnormal rectum morphology	PCSK5 EFEMP1 LPA	4.60e-05	43	23	3	MP:0000492
Domain	EGF-like_dom	PCSK5 EFEMP1 HMCN2 HYAL1 SVEP1	7.08e-05	249	33	5	IPR000742
Domain	Growth_fac_rcpt_	PCSK5 EFEMP1 HMCN2 SVEP1	1.59e-04	156	33	4	IPR009030
Domain	OA_transporter	SLCO1B3 SLCO1B1	1.98e-04	12	33	2	IPR004156
Domain	OATP	SLCO1B3 SLCO1B1	1.98e-04	12	33	2	PF03137
Domain	Kringle	LPA ROR1	4.05e-04	17	33	2	IPR000001
Domain	Kringle	LPA ROR1	4.05e-04	17	33	2	PF00051
Domain	KRINGLE_1	LPA ROR1	4.05e-04	17	33	2	PS00021
Domain	Kringle_CS	LPA ROR1	4.05e-04	17	33	2	IPR018056
Domain	KR	LPA ROR1	4.05e-04	17	33	2	SM00130
Domain	KRINGLE_2	LPA ROR1	4.05e-04	17	33	2	PS50070
Domain	EGF_CA	EFEMP1 HMCN2 SVEP1	4.65e-04	86	33	3	PF07645
Domain	EGF_Ca-bd_CS	EFEMP1 HMCN2 SVEP1	6.62e-04	97	33	3	IPR018097
Domain	EGF_CA	EFEMP1 HMCN2 SVEP1	7.02e-04	99	33	3	PS01187
Domain	ASX_HYDROXYL	EFEMP1 HMCN2 SVEP1	7.23e-04	100	33	3	PS00010
Domain	zf-CCHC	ERVK-5 ERVK-6	7.48e-04	23	33	2	PF00098
Domain	EGF_3	EFEMP1 HMCN2 HYAL1 SVEP1	7.51e-04	235	33	4	PS50026
Domain	EGF	PCSK5 EFEMP1 HYAL1 SVEP1	7.51e-04	235	33	4	SM00181
Domain	EGF-type_Asp/Asn_hydroxyl_site	EFEMP1 HMCN2 SVEP1	8.57e-04	106	33	3	IPR000152
Domain	Ephrin_rec_like	PCSK5 SVEP1	8.85e-04	25	33	2	SM01411
Domain	Tyr-kin_ephrin_A/B_rcpt-like	PCSK5 SVEP1	8.85e-04	25	33	2	IPR011641
Domain	EGF_1	EFEMP1 HMCN2 HYAL1 SVEP1	1.02e-03	255	33	4	PS00022
Domain	EGF-like_CS	EFEMP1 HMCN2 HYAL1 SVEP1	1.11e-03	261	33	4	IPR013032
Domain	EGF_2	EFEMP1 HMCN2 HYAL1 SVEP1	1.17e-03	265	33	4	PS01186
Domain	EGF_CA	EFEMP1 HMCN2 SVEP1	1.29e-03	122	33	3	SM00179
Domain	EGF-like_Ca-bd_dom	EFEMP1 HMCN2 SVEP1	1.35e-03	124	33	3	IPR001881
Domain	Kringle-like	LPA ROR1	1.45e-03	32	33	2	IPR013806
Domain	ZF_CCHC	ERVK-5 ERVK-6	1.74e-03	35	33	2	PS50158
Domain	Kazal_2	SLCO1B3 SLCO1B1	1.84e-03	36	33	2	PF07648
Domain	KAZAL	SLCO1B3 SLCO1B1	2.98e-03	46	33	2	SM00280
Domain	KAZAL_2	SLCO1B3 SLCO1B1	3.52e-03	50	33	2	PS51465
Domain	Kazal_dom	SLCO1B3 SLCO1B1	3.66e-03	51	33	2	IPR002350
Domain	ZnF_C2HC	ERVK-5 ERVK-6	4.24e-03	55	33	2	SM00343
Domain	Znf_CCHC	ERVK-5 ERVK-6	4.24e-03	55	33	2	IPR001878
Domain	Retrov_capsid_C	ERVK-5 ERVK-6	4.86e-03	59	33	2	IPR008916
Pathway	REACTOME_ATORVASTATIN_ADME	SLCO1B3 SLCO1B1	9.10e-05	9	23	2	M45020
Pathway	PID_AR_PATHWAY	NRIP1 TCF4 BRCA1	1.28e-04	61	23	3	M58
Pathway	REACTOME_TRANSPORT_OF_ORGANIC_ANIONS	SLCO1B3 SLCO1B1	1.39e-04	11	23	2	M930
Pathway	REACTOME_TRANSPORT_OF_ORGANIC_ANIONS	SLCO1B3 SLCO1B1	1.66e-04	12	23	2	MM15476
Pathway	WP_ENTEROHEPATIC_CIRCULATION_OF_BILE_ACIDS	SLCO1B3 SLCO1B1	1.66e-04	12	23	2	M48096
Pathway	WP_SULFATASE_AND_AROMATASE_PATHWAY	SLCO1B3 SLCO1B1	2.29e-04	14	23	2	M48085
Pathway	REACTOME_HEME_DEGRADATION	SLCO1B3 SLCO1B1	2.64e-04	15	23	2	M27060
Pathway	REACTOME_ATORVASTATIN_ADME	SLCO1B3 SLCO1B1	2.64e-04	15	23	2	MM15697
Pathway	REACTOME_RECYCLING_OF_BILE_ACIDS_AND_SALTS	SLCO1B3 SLCO1B1	3.83e-04	18	23	2	M4862
Pathway	REACTOME_RECYCLING_OF_BILE_ACIDS_AND_SALTS	SLCO1B3 SLCO1B1	4.28e-04	19	23	2	MM14612
Pathway	REACTOME_HEME_DEGRADATION	SLCO1B3 SLCO1B1	4.75e-04	20	23	2	MM14721
Pathway	REACTOME_SLC_TRANSPORTER_DISORDERS	SLCO1B3 SLCO1B1 HEPH	5.37e-04	99	23	3	M27474
Pathway	BIOCARTA_CARM_ER_PATHWAY	NRIP1 BRCA1	8.08e-04	26	23	2	M2499
Pathway	REACTOME_METABOLISM_OF_PORPHYRINS	SLCO1B3 SLCO1B1	8.72e-04	27	23	2	M1088
Pathway	WP_DISORDERS_OF_BILE_ACID_SYNTHESIS_AND_BILIARY_TRANSPORT	SLCO1B3 SLCO1B1	1.01e-03	29	23	2	M45551
Pathway	WP_PREGNANE_X_RECEPTOR_PATHWAY	NRIP1 SLCO1B1	1.23e-03	32	23	2	M39567
Pathway	REACTOME_METABOLISM_OF_PORPHYRINS	SLCO1B3 SLCO1B1	1.23e-03	32	23	2	MM14719
Pathway	REACTOME_PLASMA_LIPOPROTEIN_REMODELING	PCSK5 LPA	1.38e-03	34	23	2	M27842
Pathway	WP_ATM_SIGNALING	TLK1 BRCA1	1.91e-03	40	23	2	M39433
Pathway	REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES	SLCO1B3 SLCO1B1	2.01e-03	41	23	2	MM15075
Pathway	REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES	SLCO1B3 SLCO1B1	2.21e-03	43	23	2	M881
Pathway	REACTOME_BILE_ACID_AND_BILE_SALT_METABOLISM	SLCO1B3 SLCO1B1	2.31e-03	44	23	2	M499
Pathway	PID_HNF3A_PATHWAY	NRIP1 BRCA1	2.31e-03	44	23	2	M285
Pathway	REACTOME_BILE_ACID_AND_BILE_SALT_METABOLISM	SLCO1B3 SLCO1B1	2.42e-03	45	23	2	MM14751
Pathway	REACTOME_HEME_SIGNALING	NRIP1 RAI1	2.86e-03	49	23	2	M41832
Pathway	REACTOME_DISORDERS_OF_TRANSMEMBRANE_TRANSPORTERS	SLCO1B3 SLCO1B1 HEPH	2.86e-03	177	23	3	M27476
Pathway	WP_WNT_SIGNALING_WP363	TCF4 ROR1	3.09e-03	51	23	2	M39721
Pubmed	A revised nomenclature for transcribed human endogenous retroviral loci.	ERVK-18 ERVK-8 ERVK-5 ERVK-6 ERVK-19 ERVK-7 ERVK-21 ERVK-25 ERVK-24	1.33e-15	94	40	9	21542922
Pubmed	Quantitation of HERV-K env gene expression and splicing in human breast cancer.	ERVK-18 ERVK-6 ERVK-19 ERVK-7 ERVK-21	1.55e-15	5	40	5	12629516
Pubmed	Genomewide screening for fusogenic human endogenous retrovirus envelopes identifies syncytin 2, a gene conserved on primate evolution.	ERVK-8 ERVK-6 ERVK-19 ERVK-21	7.37e-10	12	40	4	14557543
Pubmed	Genome-wide screening, cloning, chromosomal assignment, and expression of full-length human endogenous retrovirus type K.	ERVK-18 ERVK-6 ERVK-19	1.41e-09	3	40	3	10516026
Pubmed	Expression patterns of transcribed human endogenous retrovirus HERV-K(HML-2) loci in human tissues and the need for a HERV Transcriptome Project.	ERVK-18 ERVK-21 ERVK-25 ERVK-24	4.54e-09	18	40	4	18664271
Pubmed	Many human endogenous retrovirus K (HERV-K) proviruses are unique to humans.	ERVK-6 ERVK-7 ERVK-24	5.63e-09	4	40	3	10469592
Pubmed	Human endogenous retrovirus K10: expression of Gag protein and detection of antibodies in patients with seminomas.	ERVK-5 ERVK-6 ERVK-19	5.63e-09	4	40	3	7983737
Pubmed	Transcriptionally active HERV-K genes: identification, isolation, and chromosomal mapping.	ERVK-5 ERVK-6 ERVK-7	1.41e-08	5	40	3	11401426
Pubmed	Survey of human genes of retroviral origin: identification and transcriptome of the genes with coding capacity for complete envelope proteins.	ERVK-6 ERVK-19 ERVK-21	1.68e-07	10	40	3	12970426
Pubmed	Interaction of oral antidiabetic drugs with hepatic uptake transporters: focus on organic anion transporting polypeptides and organic cation transporter 1.	SLCO1B3 SLCO1B1	1.29e-06	2	40	2	18314419
Pubmed	OATP 1B1/1B3 expression in hepatocellular carcinomas treated with orthotopic liver transplantation.	SLCO1B3 SLCO1B1	1.29e-06	2	40	2	21691816
Pubmed	Linking organic anion transporting polypeptide 1B1 and 1B3 (OATP1B1 and OATP1B3) interaction profiles to hepatotoxicity - The hyperbilirubinemia use case.	SLCO1B3 SLCO1B1	1.29e-06	2	40	2	28063966
Pubmed	Long-lasting inhibitory effects of cyclosporin A, but not tacrolimus, on OATP1B1- and OATP1B3-mediated uptake.	SLCO1B3 SLCO1B1	1.29e-06	2	40	2	22240838
Pubmed	Modulation of transporter activity of OATP1B1 and OATP1B3 by the major active components of Radix Ophiopogonis.	SLCO1B3 SLCO1B1	1.29e-06	2	40	2	29944058
Pubmed	Human organic anion transporter 1B1 and 1B3 function as bidirectional carriers and do not mediate GSH-bile acid cotransport.	SLCO1B3 SLCO1B1	1.29e-06	2	40	2	17412826
Pubmed	SLCO1B1 and SLCO1B3 genetic mutations in Taiwanese patients with Rotor syndrome.	SLCO1B3 SLCO1B1	1.29e-06	2	40	2	36964102
Pubmed	Expression of human endogenous retrovirus type K envelope glycoprotein in insect and mammalian cells.	ERVK-6 ERVK-19	1.29e-06	2	40	2	9060628
Pubmed	Contribution of OATP1B1 and OATP1B3 to the disposition of sorafenib and sorafenib-glucuronide.	SLCO1B3 SLCO1B1	1.29e-06	2	40	2	23340295
Pubmed	Evolutionary relationships within a subgroup of HERV-K-related human endogenous retroviruses.	ERVK-6 ERVK-19	1.29e-06	2	40	2	9460924
Pubmed	Further Studies to Support the Use of Coproporphyrin I and III as Novel Clinical Biomarkers for Evaluating the Potential for Organic Anion Transporting Polypeptide 1B1 and OATP1B3 Inhibition.	SLCO1B3 SLCO1B1	1.29e-06	2	40	2	29777022
Pubmed	Down-regulation of OATP1B proteins correlates with hyperbilirubinemia in advanced cholestasis.	SLCO1B3 SLCO1B1	1.29e-06	2	40	2	26191226
Pubmed	Visualization of hepatic uptake transporter function in healthy subjects by using gadoxetic acid-enhanced MR imaging.	SLCO1B3 SLCO1B1	1.29e-06	2	40	2	22771883
Pubmed	Utility of Oatp1a/1b-knockout and OATP1B1/3-humanized mice in the study of OATP-mediated pharmacokinetics and tissue distribution: case studies with pravastatin, atorvastatin, simvastatin, and carboxydichlorofluorescein.	SLCO1B3 SLCO1B1	1.29e-06	2	40	2	24194513
Pubmed	Establishment of a set of double transfectants coexpressing organic anion transporting polypeptide 1B3 and hepatic efflux transporters for the characterization of the hepatobiliary transport of telmisartan acylglucuronide.	SLCO1B3 SLCO1B1	1.29e-06	2	40	2	18180273
Pubmed	Structure of human drug transporters OATP1B1 and OATP1B3.	SLCO1B3 SLCO1B1	1.29e-06	2	40	2	37723174
Pubmed	Evaluation of organic anion transporting polypeptide 1B1 and 1B3 humanized mice as a translational model to study the pharmacokinetics of statins.	SLCO1B3 SLCO1B1	1.29e-06	2	40	2	24855184
Pubmed	Preclinical Mouse Models To Study Human OATP1B1- and OATP1B3-Mediated Drug-Drug Interactions in Vivo.	SLCO1B3 SLCO1B1	1.29e-06	2	40	2	26474710
Pubmed	Effects of anthocyans on the expression of organic anion transporting polypeptides (SLCOs/OATPs) in primary human hepatocytes.	SLCO1B3 SLCO1B1	1.29e-06	2	40	2	25578040
Pubmed	Effects of Rifampin, a potent inducer of drug-metabolizing enzymes and an inhibitor of OATP1B1/3 transport, on the single dose pharmacokinetics of anacetrapib.	SLCO1B3 SLCO1B1	1.29e-06	2	40	2	23670789
Pubmed	Prediction of organic anion-transporting polypeptide 1B1- and 1B3-mediated hepatic uptake of statins based on transporter protein expression and activity data.	SLCO1B3 SLCO1B1	1.29e-06	2	40	2	24989890
Pubmed	Bosentan is a substrate of human OATP1B1 and OATP1B3: inhibition of hepatic uptake as the common mechanism of its interactions with cyclosporin A, rifampicin, and sildenafil.	SLCO1B3 SLCO1B1	1.29e-06	2	40	2	17496208
Pubmed	Rotor Syndrome	SLCO1B3 SLCO1B1	1.29e-06	2	40	2	23236639
Pubmed	Expression Patterns of Organic Anion Transporting Polypeptides 1B1 and 1B3 Protein in Human Pediatric Liver.	SLCO1B3 SLCO1B1	1.29e-06	2	40	2	27098745
Pubmed	Introduction of aromatic ring-containing substituents in cyclic nucleotides is associated with inhibition of toxin uptake by the hepatocyte transporters OATP 1B1 and 1B3.	SLCO1B3 SLCO1B1	1.29e-06	2	40	2	24740327
Pubmed	Expression of organic anion-transporting polypeptides 1B1 and 1B3 in ovarian cancer cells: relevance for paclitaxel transport.	SLCO1B3 SLCO1B1	1.29e-06	2	40	2	21719246
Pubmed	Organic anion transporting polypeptide 1B1 (OATP1B1) and OATP1B3: genetic variability and haplotype analysis in white Canadians.	SLCO1B3 SLCO1B1	1.29e-06	2	40	2	20877131
Pubmed	Transport of fluorescent chenodeoxycholic acid via the human organic anion transporters OATP1B1 and OATP1B3.	SLCO1B3 SLCO1B1	1.29e-06	2	40	2	16534140
Pubmed	UGT-dependent regioselective glucuronidation of ursodeoxycholic acid and obeticholic acid and selective transport of the consequent acyl glucuronides by OATP1B1 and 1B3.	SLCO1B3 SLCO1B1	1.29e-06	2	40	2	31299240
Pubmed	In vitro OATP1B1 and OATP1B3 inhibition is associated with observations of benign clinical unconjugated hyperbilirubinemia.	SLCO1B3 SLCO1B1	1.29e-06	2	40	2	23886114
Pubmed	OATP1B1/1B3 activity in plated primary human hepatocytes over time in culture.	SLCO1B3 SLCO1B1	1.29e-06	2	40	2	21787759
Pubmed	Interferon-alpha-induced endogenous superantigen. a model linking environment and autoimmunity.	ERVK-18 ERVK-6	1.29e-06	2	40	2	11672541
Pubmed	Effect of pregnane X receptor ligands on transport mediated by human OATP1B1 and OATP1B3.	SLCO1B3 SLCO1B1	1.29e-06	2	40	2	18321482
Pubmed	Preincubation With Everolimus and Sirolimus Reduces Organic Anion-Transporting Polypeptide (OATP)1B1- and 1B3-Mediated Transport Independently of mTOR Kinase Inhibition: Implication in Assessing OATP1B1- and OATP1B3-Mediated Drug-Drug Interactions.	SLCO1B3 SLCO1B1	3.87e-06	3	40	2	31047942
Pubmed	Multiple Genetic Modifiers of Bilirubin Metabolism Involvement in Significant Neonatal Hyperbilirubinemia in Patients of Chinese Descent.	SLCO1B3 SLCO1B1	3.87e-06	3	40	2	26146841
Pubmed	SLCO1B1, SLCO2B1, and SLCO1B3 polymorphisms and susceptibility to bladder cancer risk.	SLCO1B3 SLCO1B1	3.87e-06	3	40	2	24762081
Pubmed	Characterization of organic anion transporting polypeptide 1b2-null mice: essential role in hepatic uptake/toxicity of phalloidin and microcystin-LR.	SLCO1B3 SLCO1B1	3.87e-06	3	40	2	18296417
Pubmed	Interaction Between Sex and Organic Anion-Transporting Polypeptide 1b2 on the Pharmacokinetics of Regorafenib and Its Metabolites Regorafenib-N-Oxide and Regorafenib-Glucuronide in Mice.	SLCO1B3 SLCO1B1	3.87e-06	3	40	2	30955241
Pubmed	Effects of tuberculosis, race, and human gene SLCO1B1 polymorphisms on rifampin concentrations.	SLCO1B3 SLCO1B1	3.87e-06	3	40	2	20660695
Pubmed	Influence of drug formulation on OATP1B-mediated transport of paclitaxel.	SLCO1B3 SLCO1B1	3.87e-06	3	40	2	24755470
Pubmed	OATP1B2 deficiency protects against paclitaxel-induced neurotoxicity.	SLCO1B3 SLCO1B1	3.87e-06	3	40	2	29337310
Pubmed	Influence of genomic ancestry on the distribution of SLCO1B1, SLCO1B3 and ABCB1 gene polymorphisms among Brazilians.	SLCO1B3 SLCO1B1	3.87e-06	3	40	2	22136368
Pubmed	Expression of Oatp2 in the Brain and Liver of Alzheimer Disease Mouse Model.	SLCO1B3 SLCO1B1	3.87e-06	3	40	2	31967785
Pubmed	Organic Anion Transporting Polypeptides Contribute to the Disposition of Perfluoroalkyl Acids in Humans and Rats.	SLCO1B3 SLCO1B1	3.87e-06	3	40	2	28013215
Pubmed	The role of organic anion-transporting polypeptides and their common genetic variants in mycophenolic acid pharmacokinetics.	SLCO1B3 SLCO1B1	3.87e-06	3	40	2	19890249
Pubmed	HIV protease inhibitors are substrates for OATP1A2, OATP1B1 and OATP1B3 and lopinavir plasma concentrations are influenced by SLCO1B1 polymorphisms.	SLCO1B3 SLCO1B1	3.87e-06	3	40	2	20051929
Pubmed	Impact of regulatory polymorphisms in organic anion transporter genes in the human liver.	SLCO1B3 SLCO1B1	3.87e-06	3	40	2	19620935
Pubmed	Identification of novel cell-impermeant fluorescent substrates for testing the function and drug interaction of Organic Anion-Transporting Polypeptides, OATP1B1/1B3 and 2B1.	SLCO1B3 SLCO1B1	3.87e-06	3	40	2	29422623
Pubmed	Human OATP1B1, OATP1B3 and OATP1A2 can mediate the in vivo uptake and clearance of docetaxel.	SLCO1B3 SLCO1B1	3.87e-06	3	40	2	24825069
Pubmed	Association study of genetic polymorphisms of drug transporters, SLCO1B1, SLCO1B3 and ABCC2, in African-Americans, Hispanics and Caucasians and olmesartan exposure.	SLCO1B3 SLCO1B1	3.87e-06	3	40	2	22695893
Pubmed	Role of the murine organic anion-transporting polypeptide 1b2 (Oatp1b2) in drug disposition and hepatotoxicity.	SLCO1B3 SLCO1B1	3.87e-06	3	40	2	18492796
Pubmed	Differential Expression of OATP1B3 Mediates Unconjugated Testosterone Influx.	SLCO1B3 SLCO1B1	3.87e-06	3	40	2	28389619
Pubmed	Organic anion transporting polypeptide (OATP)-mediated transport of coproporphyrins I and III.	SLCO1B3 SLCO1B1	3.87e-06	3	40	2	26383540
Pubmed	Organic anion transporting polypeptide 1B transporters modulate hydroxyurea pharmacokinetics.	SLCO1B3 SLCO1B1	3.87e-06	3	40	2	23986199
Pubmed	Targeted disruption of murine organic anion-transporting polypeptide 1b2 (Oatp1b2/Slco1b2) significantly alters disposition of prototypical drug substrates pravastatin and rifampin.	SLCO1B3 SLCO1B1	3.87e-06	3	40	2	18413659
Pubmed	Alteration in placental expression of bile acids transporters OATP1A2, OATP1B1, OATP1B3 in intrahepatic cholestasis of pregnancy.	SLCO1B3 SLCO1B1	3.87e-06	3	40	2	22203093
Pubmed	Organic anion-transporting polypeptide 1b2 (Oatp1b2) is important for the hepatic uptake of unconjugated bile acids: Studies in Oatp1b2-null mice.	SLCO1B3 SLCO1B1	3.87e-06	3	40	2	20949553
Pubmed	Organic Anion Transporting Polypeptide-Mediated Hepatic Uptake of Glucuronide Metabolites of Androgens.	SLCO1B3 SLCO1B1	3.87e-06	3	40	2	32587096
Pubmed	Comparison of genetic variations of the SLCO1B1, SLCO1B3, and SLCO2B1 genes among five ethnic groups.	SLCO1B3 SLCO1B1	3.87e-06	3	40	2	26409184
Pubmed	Identification, expression, and functional characterization of full-length and splice variants of murine organic anion transporting polypeptide 1b2.	SLCO1B3 SLCO1B1	3.87e-06	3	40	2	19400585
Pubmed	Synergistic interaction between genetics and disease on pravastatin disposition.	SLCO1B3 SLCO1B1	3.87e-06	3	40	2	24613363
Pubmed	OATPB1/B3 and MRP3 expression in hepatocellular adenoma predicts Gd-EOB-DTPA uptake and correlates with risk of malignancy.	SLCO1B3 SLCO1B1	3.87e-06	3	40	2	30218633
Pubmed	Association of neonatal hyperbilirubinemia in breast-fed infants with UGT1A1 or SLCOs polymorphisms.	SLCO1B3 SLCO1B1	3.87e-06	3	40	2	25391605
Pubmed	Full-length cDNA cloning and genomic organization of the mouse liver-specific organic anion transporter-1 (lst-1).	SLCO1B3 SLCO1B1	3.87e-06	3	40	2	10833452
Pubmed	Localization and genomic organization of a new hepatocellular organic anion transporting polypeptide.	SLCO1B3 SLCO1B1	3.87e-06	3	40	2	10779507
Pubmed	Impact of Oatp1c1 deficiency on thyroid hormone metabolism and action in the mouse brain.	SLCO1B3 SLCO1B1	7.73e-06	4	40	2	22294745
Pubmed	Organic anion transporting polypeptide 1a/1b-knockout mice provide insights into hepatic handling of bilirubin, bile acids, and drugs.	SLCO1B3 SLCO1B1	7.73e-06	4	40	2	20644253
Pubmed	Influence of SLCO1B1, 1B3, 2B1 and ABCC2 genetic polymorphisms on mycophenolic acid pharmacokinetics in Japanese renal transplant recipients.	SLCO1B3 SLCO1B1	7.73e-06	4	40	2	17906856
Pubmed	Digoxin is not a substrate for organic anion-transporting polypeptide transporters OATP1A2, OATP1B1, OATP1B3, and OATP2B1 but is a substrate for a sodium-dependent transporter expressed in HEK293 cells.	SLCO1B3 SLCO1B1	7.73e-06	4	40	2	21849517
Pubmed	Protection against phalloidin-induced liver injury by oleanolic acid involves Nrf2 activation and suppression of Oatp1b2.	SLCO1B3 SLCO1B1	7.73e-06	4	40	2	25280775
Pubmed	Genetic polymorphisms of uptake (OATP1B1, 1B3) and efflux (MRP2, BCRP) transporters: implications for inter-individual differences in the pharmacokinetics and pharmacodynamics of statins and other clinically relevant drugs.	SLCO1B3 SLCO1B1	7.73e-06	4	40	2	19442037
Pubmed	Contribution of Organic Anion-Transporting Polypeptides 1A/1B to Doxorubicin Uptake and Clearance.	SLCO1B3 SLCO1B1	7.73e-06	4	40	2	27777271
Pubmed	Cellular crosstalk regulates the aqueous humor outflow pathway and provides new targets for glaucoma therapies.	ANGPT1 SVEP1	1.29e-05	5	40	2	34663817
Pubmed	Associations between UGT1A1, SLCO1B1, SLCO1B3, BLVRA and HMOX1 polymorphisms and susceptibility to neonatal severe hyperbilirubinemia in Chinese Han population.	SLCO1B3 SLCO1B1	1.29e-05	5	40	2	38279097
Pubmed	Angiogenetic axis angiopoietins/Tie2 and VEGF in familial breast cancer.	ANGPT1 BRCA1	1.29e-05	5	40	2	23232696
Pubmed	OATP1A/1B transporters affect irinotecan and SN-38 pharmacokinetics and carboxylesterase expression in knockout and humanized transgenic mice.	SLCO1B3 SLCO1B1	1.29e-05	5	40	2	24194565
Pubmed	Polymorphisms of the nuclear receptor pregnane X receptor and organic anion transporter polypeptides 1A2, 1B1, 1B3, and 2B1 are not associated with breast cancer risk.	SLCO1B3 SLCO1B1	1.29e-05	5	40	2	20635135
Pubmed	Complete OATP1B1 and OATP1B3 deficiency causes human Rotor syndrome by interrupting conjugated bilirubin reuptake into the liver.	SLCO1B3 SLCO1B1	1.93e-05	6	40	2	22232210
Pubmed	Polymorphisms in cytochromes P450 2C8 and 3A5 are associated with paclitaxel neurotoxicity.	SLCO1B3 SLCO1B1	1.93e-05	6	40	2	20212519
Pubmed	Human endogenous retrovirus HERV-K(HML-2) proviruses with Rec protein coding capacity and transcriptional activity.	ERVK-6 ERVK-19	1.93e-05	6	40	2	15063128
Pubmed	Analysis of DNA methylation and histone modification profiles of liver-specific transporters.	SLCO1B3 SLCO1B1	1.93e-05	6	40	2	19047482
Pubmed	Mechanisms of pH-gradient driven transport mediated by organic anion polypeptide transporters.	SLCO1B3 SLCO1B1	3.60e-05	8	40	2	19129463
Pubmed	Critical role of PPAR-alpha in perfluorooctanoic acid- and perfluorodecanoic acid-induced downregulation of Oatp uptake transporters in mouse livers.	SLCO1B3 SLCO1B1	5.77e-05	10	40	2	18703564
Pubmed	Pharmacogenetic analysis of lipid responses to rosuvastatin in Chinese patients.	SLCO1B3 SLCO1B1 LPA	6.13e-05	66	40	3	20679960
Pubmed	Influence of drug transporters and UGT polymorphisms on pharmacokinetics of phenolic glucuronide metabolite of mycophenolic acid in Japanese renal transplant recipients.	SLCO1B3 SLCO1B1	7.05e-05	11	40	2	18695635
Pubmed	Organic anion transporting polypeptides of the OATP/ SLC21 family: phylogenetic classification as OATP/ SLCO superfamily, new nomenclature and molecular/functional properties.	SLCO1B3 SLCO1B1	7.05e-05	11	40	2	14579113
Pubmed	The Diet1 locus confers protection against hypercholesterolemia through enhanced bile acid metabolism.	SLCO1B3 SLCO1B1	9.98e-05	13	40	2	11682476
Pubmed	Localization of Xenobiotic Transporters Expressed at the Human Blood-Testis Barrier.	SLCO1B3 SLCO1B1	1.53e-04	16	40	2	35307651
Pubmed	Polydom Is an Extracellular Matrix Protein Involved in Lymphatic Vessel Remodeling.	ANGPT1 SVEP1	1.53e-04	16	40	2	28179430
Pubmed	Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.	PCSK5 SEMA3F EFEMP1 SVEP1	1.88e-04	248	40	4	24006456
Pubmed	Changes in thyroid status during perinatal development of MCT8-deficient male mice.	SLCO1B3 SLCO1B1	1.95e-04	18	40	2	23696569
GeneFamily	Fibulins	EFEMP1 HMCN2	3.24e-05	8	20	2	556
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	HMCN2 ROR1	1.35e-02	161	20	2	593
GeneFamily	Immunoglobulin like domain containing	SEMA3F HMCN2	1.90e-02	193	20	2	594
Coexpression	SERVITJA_LIVER_HNF1A_TARGETS_DN	SLCO1B3 SLCO1B1 LECT2 LPA ROR1	2.77e-06	190	31	5	MM1311
Coexpression	NABA_MATRISOME	PCSK5 SEMA3F EFEMP1 ANGPT1 HMCN2 HYAL1 SVEP1 LPA	1.67e-05	1008	31	8	MM17056
Coexpression	NABA_MATRISOME	PCSK5 SEMA3F EFEMP1 ANGPT1 HMCN2 HYAL1 SVEP1 LPA	1.89e-05	1026	31	8	M5889
Coexpression	BENPORATH_SOX2_TARGETS	PCSK5 BAMBI EAPP RASGRF2 HEPH ROR1 ZNF646	1.92e-05	734	31	7	M3835
Coexpression	CARRILLOREIXACH_HEPATOBLASTOMA_VS_NORMAL_HYPOMETHYLATED_AND_UP	BAMBI TCF4 ANGPT1 RASGRF2	3.88e-05	162	31	4	M45037
Coexpression	HE_LIM_SUN_FETAL_LUNG_C3_OMD_POS_ENDOTHELIAL_CELL	PCSK5 SEMA3F BAMBI EFEMP1 HMCN2	5.64e-05	355	31	5	M45758
Coexpression	LEE_BMP2_TARGETS_DN	PCSK5 BAMBI CAD ANGPT1 BRCA1 UTP4 ROR1	7.22e-05	904	31	7	M2325
Coexpression	LEE_BMP2_TARGETS_DN	PCSK5 BAMBI CAD ANGPT1 BRCA1 UTP4 ROR1	8.17e-05	922	31	7	MM1068
Coexpression	GSE29618_PRE_VS_DAY7_FLU_VACCINE_PDC_UP	PCSK5 EFEMP1 SLCO1B1 LPA	8.64e-05	199	31	4	M4978
Coexpression	GSE11961_FOLLICULAR_BCELL_VS_PLASMA_CELL_DAY7_DN	NRIP1 TLK1 MTMR9 RAI1	8.81e-05	200	31	4	M9315
Coexpression	RADMACHER_AML_PROGNOSIS	SEMA3F TCF4 ANGPT1	1.20e-04	81	31	3	M7815
Coexpression	BOQUEST_STEM_CELL_UP	EFEMP1 ANGPT1 SVEP1 ROR1	2.45e-04	261	31	4	M1834
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TCF4 ANGPT1 HEPH ROR1	6.51e-06	170	32	4	876b84740e15399bfff2b9c7f0b80fd759bbdb3f
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TCF4 ANGPT1 HEPH ROR1	6.51e-06	170	32	4	1f8738acf439d893880db7e1fdc9b3615ca00c39
ToppCell	COVID-19-kidney-AQP1+SLC14A1+EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PCSK5 SEMA3F TCF4 RASGRF2	7.99e-06	179	32	4	1ce8d18f63e8dd2d3db41fbeca4601bd3b305fba
ToppCell	COVID-19-Endothelial_cells-Arterial_endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	SEMA3F TCF4 HMCN2 RASGRF2	8.90e-06	184	32	4	0f19494789f38ab1a420545e15e748ca7eb345c3
ToppCell	TCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-4\|TCGA-Pancreas / Sample_Type by Project: Shred V9	TCF4 ANGPT1 SVEP1 ROR1	8.90e-06	184	32	4	67164bb6bcae7322cb89b585c7aa10bce35b0ecd
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L4-5_PVALB_TRIM67\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PCSK5 HMCN2 RASGRF2 ROR1	8.90e-06	184	32	4	7f6c8912677764d438ab0555faca344d74c2f483
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PCSK5 TCF4 HMCN2 RASGRF2	9.89e-06	189	32	4	6463890d8dbee4bc198f91628a5f784970de786a
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PCSK5 TCF4 HMCN2 RASGRF2	1.12e-05	195	32	4	6bdef651cf73d7381e5012d0eb3c809138fb6b92
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature3_(17)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	TCF4 ANGPT1 SVEP1 ROR1	1.12e-05	195	32	4	1cdf5f296029ae424d9dba42e86a6d111e4896e6
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	TCF4 ANGPT1 SVEP1 ROR1	1.14e-05	196	32	4	1450cb69c5bf469e97c03bf1890f6f7c54165b8a
ToppCell	5'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	BAMBI TCF4 EFEMP1 ANGPT1	1.16e-05	197	32	4	ea746772adb9df4ddb0508d4ef35f2027bf09c35
ToppCell	Tracheal-NucSeq-Stromal-Fibroblastic-Fibro_myofibroblast\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PCSK5 EFEMP1 ANGPT1 SVEP1	1.16e-05	197	32	4	0dd71e399f253787fa546a7e90c5373180b89ffd
ToppCell	10x3'2.3-week_17-19-Mesenchymal_adipo-stroma\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	PCSK5 EFEMP1 ANGPT1 SVEP1	1.16e-05	197	32	4	b9745e382baa2725dfcae060701fb53f6c8a31fa
ToppCell	10x3'2.3-week_17-19-Mesenchymal_adipo\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	PCSK5 EFEMP1 ANGPT1 SVEP1	1.16e-05	197	32	4	5afddde4e2b5cd55abe11e9b9efae02dbdc3da3a
ToppCell	10x3'2.3-week_17-19-Mesenchymal_adipo-stroma-adipo-CAR\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	PCSK5 EFEMP1 ANGPT1 SVEP1	1.16e-05	197	32	4	1baffd087ca194a7355fefbb3bf67befb14fe2de
ToppCell	PCW_13-14-Mesenchymal\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	TCF4 ANGPT1 SVEP1 ROR1	1.16e-05	197	32	4	73a2085d2682d636726a5432d572ae2a3fbe1c3f
ToppCell	IPF-Stromal-Myofibroblast\|Stromal / Disease state, Lineage and Cell class	TCF4 ANGPT1 RASGRF2 ROR1	1.16e-05	197	32	4	f304d42fc4936fe20996e07c8dccc698a6e5e5ef
ToppCell	10x3'2.3-week_14-16-Mesenchymal_adipo-stroma-adipo-CAR\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	PCSK5 EFEMP1 ANGPT1 SVEP1	1.19e-05	198	32	4	a8c21f4db6730d0aa05b61fbe72bf9f7571a9015
ToppCell	10x3'2.3-week_14-16-Mesenchymal_adipo-stroma\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	PCSK5 EFEMP1 ANGPT1 SVEP1	1.19e-05	198	32	4	8b68fc887e5ad0a59ea4d93dfd1edda67030f142
ToppCell	10x3'2.3-week_14-16-Mesenchymal_adipo\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	PCSK5 EFEMP1 ANGPT1 SVEP1	1.19e-05	198	32	4	4739b2e4ab141c66772e61686b45614a1839483e
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	TCF4 ANGPT1 SVEP1 ROR1	1.19e-05	198	32	4	17dc055e2a289496d9c5cdbf3297bdf906dc6d22
ToppCell	PCW_10-12-Mesenchymal\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	TCF4 ANGPT1 SVEP1 ROR1	1.21e-05	199	32	4	a09292de4c4447b8eee55d401808e43b817321cc
ToppCell	Neuronal-Inhibitory-iA-iA_3(VIP)-VIP_1-CASC6\|Neuronal / cells hierarchy compared to all cells using T-Statistic	PCSK5 EFEMP1 ANGPT1 HEPH	1.24e-05	200	32	4	1d397ad55f0f7a7dd72aa5a3331d2e0db07f0d39
ToppCell	wk_15-18-Mesenchymal-Fibroblast\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	BAMBI ANGPT1 SVEP1 ROR1	1.24e-05	200	32	4	4f624c3c57d1a84baa86d0830cb1b83ae110bf67
ToppCell	Neuronal-Inhibitory-iA-iA_3(VIP)-VIP_1-CASC6-L2-3\|Neuronal / cells hierarchy compared to all cells using T-Statistic	PCSK5 EFEMP1 ANGPT1 HEPH	1.24e-05	200	32	4	8576906df19ea1383e2221709b3b309b1bbba28d
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Serpinf1-Serpinf1_Clrn1\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	BAMBI RASGRF2 ROR1	8.25e-05	118	32	3	702548d8187d54e8814375e5ae7609631fc71d5f
ToppCell	356C-Myeloid-Macrophage-SPP1+_Macrophage\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	PCSK5 BAMBI ANGPT1	9.79e-05	125	32	3	43aa4b77dccf0ea2979218826af16034f2017c3a
ToppCell	primary_visual_cortex-Non-neuronal-leptomeningeal_cell-VLMC-VLMC_Spp1_Col15a1\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	EFEMP1 SVEP1 ROR1	1.43e-04	142	32	3	f4e4cde228149d5a536fbf0517ed71d81e296faf
ToppCell	10x5'-bone_marrow-Myeloid_Monocytic-Cycling_mono\|bone_marrow / Manually curated celltypes from each tissue	SEMA3F ZNF516-DT BRCA1	1.61e-04	148	32	3	de35eeefad0e27a0d127e2e4bedead2bddb75152
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell_prolif\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PCSK5 TCF4 RASGRF2	1.81e-04	154	32	3	e51a5114f0ec38f997f5b8bbf3a7770f98595474
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-high_Fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LPA HEPH ROR1	1.99e-04	159	32	3	cbb331eb689d8cea9e1146ba85e0a05d23301c47
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-high_Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LPA HEPH ROR1	1.99e-04	159	32	3	330ecbba97d47bc818a5e8d1d84b05d056bd831e
ToppCell	metastatic_Brain-T/NK_cells-Cytotoxic_CD8+_T\|T/NK_cells / Location, Cell class and cell subclass	PCSK5 SEMA3F EFEMP1	2.07e-04	161	32	3	e6e294b4ba911c1327664f1a0f93207096c6de03
ToppCell	10x5'v1-week_17-19-Hematopoietic-HSC/MPP_and_pro-HSC/MPP\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	CACNA1F NRIP1 ANGPT1	2.07e-04	161	32	3	aee74a2e7a8acd2950341963f1c04b59c7862183
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TCF4 HEPH ROR1	2.07e-04	161	32	3	1b805f77790aeb8a71b08bfac2fe2eed7343258f
ToppCell	356C-Myeloid-Macrophage-SPP1+_Macrophage\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	PCSK5 BAMBI ANGPT1	2.18e-04	164	32	3	d6806deabf5f5c355934387be2baae125ac33fb8
ToppCell	Bac-SEP-Myeloid-tDC\|Bac-SEP / Disease, Lineage and Cell Type	CACNA1F TCF4 CAD	2.22e-04	165	32	3	8728f927502e56f2768b4224e9111939d3d7815a
ToppCell	TCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Diffuse-3\|TCGA-Stomach / Sample_Type by Project: Shred V9	TCF4 SVEP1 PARP15	2.30e-04	167	32	3	d2230c894ccf9dbba9196e079ae81f384d43da63
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PCSK5 EFEMP1 SVEP1	2.34e-04	168	32	3	4b2d29a7843bf45922038c093ca7ec0600756adc
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-4_VIP_CHRNA2\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ANGPT1 SVEP1 HEPH	2.34e-04	168	32	3	11ab08e373abe4bbd0f2134db38a2e8efa0eb159
ToppCell	TCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocellular_Carcinoma-6\|TCGA-Liver / Sample_Type by Project: Shred V9	TCF4 SVEP1 HEPH	2.38e-04	169	32	3	e992530776cab922d0360b275fb9cb8bd0017b06
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1-6_VIP_PENK\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PCSK5 SEMA3F HMCN2	2.38e-04	169	32	3	eb3b8e473192c4b8688f2f8da400116dd6fe193d
ToppCell	droplet-Pancreas-Exocrine-18m\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA3F EFEMP1 ANGPT1	2.38e-04	169	32	3	53690d6f9712b54aa99a0408aae930d64ae478e5
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PCSK5 EFEMP1 SVEP1	2.47e-04	171	32	3	5d31fc9b60329d4ae3c77e4ca679359d9314397d
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ANGPT1 SVEP1 HEPH	2.51e-04	172	32	3	1ef243bce63d841c25e4b74d029d1377f84bcc3d
ToppCell	Control-Endothelial_cells-Systemic_venous_endothelial_cells\|Control / group, cell type (main and fine annotations)	SEMA3F TCF4 RASGRF2	2.51e-04	172	32	3	c55dce1ed3ed7312394b4e050e1de852a994e130
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ANGPT1 SVEP1 HEPH	2.51e-04	172	32	3	ab1c81be29f93ca8920c6ab5ab92f497a9256d3f
ToppCell	droplet-Liver-Npc-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA3F TCF4 RASGRF2	2.51e-04	172	32	3	a6fb1bde8d942c7b5caaf7bd14de0b7ce32fda55
ToppCell	Endothelial-B-IPF_04\|World / lung cells shred on cell class, cell subclass, sample id	TCF4 EFEMP1 HEPH	2.51e-04	172	32	3	d4e98ff9c7cbc95457e1d71fa60f151a2f178dae
ToppCell	AT1-AT2_cells-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	SEMA3F SLCO1B3 EFEMP1	2.51e-04	172	32	3	0be41df5d35d818deb7316ac21c9366eb4b7bfd1
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6-Inh_L1-2_PAX6_SCGN\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ANGPT1 SVEP1 ROR1	2.55e-04	173	32	3	33170a1cc0bc87504d0501fc257a32ff17e02314
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L2-4_VIP_LGI2\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ANGPT1 LECT2 HEPH	2.60e-04	174	32	3	ef9232610829cd3a34f0c0e284cdbee449c19c00
ToppCell	metastatic_Lymph_Node-Endothelial_cells-Lymphatic_ECs\|metastatic_Lymph_Node / Location, Cell class and cell subclass	SEMA3F EFEMP1 HEPH	2.60e-04	174	32	3	d551bc29afef071adf4c9bb80345352ec33441d8
ToppCell	TCGA-Liver\|World / Sample_Type by Project: Shred V9	SLCO1B1 LECT2 LPA	2.60e-04	174	32	3	452932f08cf53e5949672a025d78cecb874aa4b0
ToppCell	3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PCSK5 TCF4 RASGRF2	2.60e-04	174	32	3	18ab52d8bbca0507fee220e0c4fc765fc47dda34
ToppCell	COVID-19-kidney-PCT-S3-2\|kidney / Disease (COVID-19 only), tissue and cell type	SLCO1B3 SLCO1B1 LPA	2.60e-04	174	32	3	5aa2fb631505600f37d2b87b02def7be139dc262
ToppCell	TCGA-Colorectal-Recurrent_Tumor\|TCGA-Colorectal / Sample_Type by Project: Shred V9	SLCO1B1 LECT2 LPA	2.64e-04	175	32	3	7f74961436f88c0e380819095e6104489914d765
ToppCell	TCGA-Colorectal-Recurrent_Tumor-Colorectal_Adenocarcinoma\|TCGA-Colorectal / Sample_Type by Project: Shred V9	SLCO1B1 LECT2 LPA	2.64e-04	175	32	3	bee8f31f036dfcf9fc6ed29156554771a9ee3c60
ToppCell	droplet-Liver-Npc-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA3F TCF4 RASGRF2	2.69e-04	176	32	3	3494ffa8555e6edf4b1250e10434bae9b73ec845
ToppCell	droplet-Liver-Npc-18m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA3F TCF4 RASGRF2	2.69e-04	176	32	3	d43f6b7828b98e1dab7b726a5f99499d65a7db80
ToppCell	COVID-19-kidney-PCT-S3-2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	SLCO1B3 SLCO1B1 LPA	2.69e-04	176	32	3	b6497324e3e52f514ce556a3fa0c3011c45dcc7b
ToppCell	LPS-IL1RA+antiTNF\|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ANGPT1 SVEP1 ROR1	2.73e-04	177	32	3	b7fee75de7e96924af488a5baa2334711889ae7c
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1-3_VIP_SSTR1\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PCSK5 EFEMP1 ANGPT1	2.73e-04	177	32	3	fdab7b7ddfb06f913b8224c0c80574dc3cf4cbd4
ToppCell	356C-Fibroblasts-Fibroblast-G-\|356C / Donor, Lineage, Cell class and subclass (all cells)	ANGPT1 SVEP1 HEPH	2.73e-04	177	32	3	7617270f49cd6b7ba66db72d20560cee985012b2
ToppCell	Endothelial-Endothelial-C\|Endothelial / shred on cell class and cell subclass (v4)	PCSK5 SLCO1B3 EFEMP1	2.73e-04	177	32	3	b5b9278dfd76b1aacd88e5fe86e91a2c9b565f87
ToppCell	356C-Fibroblasts-Fibroblast-G\|356C / Donor, Lineage, Cell class and subclass (all cells)	ANGPT1 SVEP1 HEPH	2.73e-04	177	32	3	8220cc2fc0ee8764a67a3be51d75248be2453040
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Epithelial-neuro-epithelial-K_cells_(GIP+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ZNF813 CACNA1F BAMBI	2.73e-04	177	32	3	43dce527392f3b8364bb6a55268ce9d6518d3a29
ToppCell	ASK440-Epithelial-Transformed_epithelium\|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq	ZNF808 BAMBI TCF4	2.78e-04	178	32	3	86f1741636ed3e85bb4a65f84949b718fc38c290
ToppCell	TCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-6\|TCGA-Ovary / Sample_Type by Project: Shred V9	RASGRF2 SVEP1 HEPH	2.78e-04	178	32	3	142879e9393e721f9b05a6bb46995c9d6d713c95
ToppCell	RV-11._Adipocyte\|RV / Chamber and Cluster_Paper	PCSK5 NRIP1 SVEP1	2.78e-04	178	32	3	278bbea5cf8f0589f71675c7a3d00679391b5253
ToppCell	facs-Pancreas-Endocrine-24m-Mesenchymal\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCSK5 EFEMP1 SVEP1	2.82e-04	179	32	3	6f51a4580c06fc55cc764052c9b26f7c55660282
ToppCell	facs-Pancreas-Endocrine-24m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCSK5 EFEMP1 SVEP1	2.82e-04	179	32	3	a6ce1fa338d4905bd6afef00763ac83e916a0b37
ToppCell	E18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_prolif\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PCSK5 BRCA1 ROR1	2.82e-04	179	32	3	ce3ca7f3a5864e62307aa744a3173f350a90df28
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	LECT2 SVEP1 ROR1	2.82e-04	179	32	3	0b6731d9554f8bed1899c165a50e6b329ea19a6d
ToppCell	facs-Pancreas-Endocrine-24m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCSK5 EFEMP1 SVEP1	2.82e-04	179	32	3	f14440f6ce9b4fcdd4bcb2488b949f9a0e17bc23
ToppCell	COVID-19-Heart-EC_2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PCSK5 TCF4 RASGRF2	2.82e-04	179	32	3	2a53d94f6c30bf887dfe88f1693ea057218c852d
ToppCell	COVID-19-kidney-PLVAP+EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	SEMA3F TCF4 RASGRF2	2.87e-04	180	32	3	493cf8d1a8f2a1ed2672f394a0338b110fd81d88
ToppCell	facs-Lung-24m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l49\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	BAMBI TLK1 EFEMP1	2.87e-04	180	32	3	e9785ac2806103f725f5a5208495826354ec6e22
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6-Inh_L1_PAX6_CA4\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ANGPT1 LECT2 SVEP1	2.87e-04	180	32	3	392bc71a69653ba12de31bed4e9357f181094641
ToppCell	P28-Mesenchymal-mesenchymal_fibroblast\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	EFEMP1 ANGPT1 SVEP1	2.91e-04	181	32	3	091e7975badd1ffa463a8ec87908be20781ecfd6
ToppCell	COVID-19-Endothelial_cells-Endothelial_cells_(other)\|COVID-19 / group, cell type (main and fine annotations)	SEMA3F TCF4 RASGRF2	2.91e-04	181	32	3	26eb4ee57a70dbf54e096b73129fda9dfda1f6ec
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNA1F EFEMP1 ROR1	2.91e-04	181	32	3	b45b11428d13950369347e051d4d517efb2bd4fd
ToppCell	facs-Lung-nan-3m-Mesenchymal-Alveolar_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EFEMP1 ANGPT1 SVEP1	2.96e-04	182	32	3	dbe4b2557cf19e0682ed446f8397d3a1153642f0
ToppCell	droplet-Lung-21m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PCSK5 RASGRF2 HEPH	2.96e-04	182	32	3	c7f2d24697affa530b748ab32b1d40bdc1bdc20a
ToppCell	P28-Mesenchymal\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	EFEMP1 ANGPT1 SVEP1	2.96e-04	182	32	3	69f9d44694fe4f55a971ae0ac5dc3e7448ee78f3
ToppCell	droplet-Lung-21m-Endothelial-arterial_endothelial\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PCSK5 RASGRF2 HEPH	2.96e-04	182	32	3	d95635b74e8cd8bc00bfe40340806b59fb9bee43
ToppCell	facs-Lung-nan-3m-Mesenchymal-fibroblast_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EFEMP1 ANGPT1 SVEP1	2.96e-04	182	32	3	c557de6ccd327c46e0a5423cd9936d78e0abae5f
ToppCell	P28-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	EFEMP1 ANGPT1 SVEP1	2.96e-04	182	32	3	19c5e3a9d9b3728303b682102e276adfe93aa759
ToppCell	P28-Mesenchymal-mesenchymal_fibroblast-alveolar_fibroblast_Wnt2-pa\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	EFEMP1 ANGPT1 SVEP1	3.06e-04	184	32	3	924400f47e6b2cdf7b0d538df75857935cf0209b
ToppCell	5'-Adult-Distal_Rectal-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ZNF516-DT EFEMP1 SVEP1	3.11e-04	185	32	3	9faa35ceb89ccd2979072286f063687c9f846ce3
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	LECT2 SVEP1 ROR1	3.11e-04	185	32	3	79cff4f3c6ae8e5ea60e8eae082b9275f2679ee9
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_VIP_PRSS8\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PCSK5 ANGPT1 ROR1	3.11e-04	185	32	3	4c42bd3cd72f91f4d4ebb849069a03761a2cd662
ToppCell	COVID-19-Heart-Fib_2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	TCF4 HMCN2 SVEP1	3.11e-04	185	32	3	8f95d8e591bf7379d13f5a0545b0cb49e2b1ab5d
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_2\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TCF4 ANGPT1 SVEP1	3.11e-04	185	32	3	cefd81adb480c027545a5c78dcd05669783717f4
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_artery-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SEMA3F TCF4 RASGRF2	3.11e-04	185	32	3	a7ae76058b2082020cadec49d63b9f4e24d21734
ToppCell	Mild-NK\|World / Disease group and Cell class	TCF4 ANGPT1 ROR1	3.11e-04	185	32	3	0565b7c464e1a09e596f5a0b363d2dc9b55c3c50
ToppCell	COVID-19-kidney-FLT1+PLVAP+EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	SEMA3F TCF4 RASGRF2	3.11e-04	185	32	3	673308ca0514a4d3629d61fe91e9d8fb31b72166
ToppCell	droplet-Lung-LUNG-30m-Mesenchymal-Alveolar_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EFEMP1 ANGPT1 SVEP1	3.16e-04	186	32	3	ca5e9c6531cb5d199e27509bfab1d62e3937177e
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PCSK5 RASGRF2 ROR1	3.16e-04	186	32	3	96f6603cc75fa1ffc2a2fdb94ec0ec09498e540a
ToppCell	droplet-Lung-LUNG-30m-Mesenchymal-fibroblast_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EFEMP1 ANGPT1 SVEP1	3.16e-04	186	32	3	1ed71b229f40a680071b14f5a7a19706e0fd14b1
Drug	(5-(3-(4-(2-bromo-5-fluorophenoxy)piperidin-1-yl)isoxazol-5-yl)-2H-tetrazol-2-yl)acetic acid	SLCO1B3 SLCO1B1	1.91e-06	2	32	2	ctd:C561635
Drug	rifamycin SV	SLCO1B3 SLCO1B1	1.15e-05	4	32	2	ctd:C023808
Drug	microcystin-LF	SLCO1B3 SLCO1B1	1.15e-05	4	32	2	ctd:C524165
Drug	Dihydromicrocystin Lr	SLCO1B3 SLCO1B1	1.15e-05	4	32	2	CID006441227
Drug	2,2',4,4',5,6'-hexabromodiphenyl ether	SLCO1B3 SLCO1B1	1.91e-05	5	32	2	ctd:C555859
Drug	trospium chloride	SLCO1B3 SLCO1B1	2.86e-05	6	32	2	ctd:C003330
Drug	prednisolone phosphate	SLCO1B3 SLCO1B1	2.86e-05	6	32	2	CID000004896
Drug	nateglinide	SLCO1B3 SLCO1B1	4.00e-05	7	32	2	ctd:C060142
Drug	demethylphalloin	SLCO1B3 SLCO1B1	4.00e-05	7	32	2	CID000114793
Drug	TAK-875	SLCO1B3 SLCO1B1	5.33e-05	8	32	2	ctd:C557331
Drug	Fusidic Acid	SLCO1B3 SLCO1B1	5.33e-05	8	32	2	ctd:D005672
Drug	NSC263652	SLCO1B3 SLCO1B1	5.33e-05	8	32	2	CID000429721
Drug	5-(N-(4-((4-ethylbenzyl)thio)phenyl)sulfamoyl)-2-methylbenzoic acid	SLCO1B3 SLCO1B1	6.85e-05	9	32	2	ctd:C000588958
Drug	Y-S-H	SLCO1B3 SLCO1B1	8.55e-05	10	32	2	CID000449035
Drug	taurodeoxycholate	ERVK-6 SLCO1B1 HEPH	9.91e-05	64	32	3	CID000010594
Drug	repaglinide	SLCO1B3 SLCO1B1	1.04e-04	11	32	2	ctd:C072379
Drug	microcystin	SLCO1B3 SLCO1B1	1.04e-04	11	32	2	ctd:C078588
Drug	glimepiride	SLCO1B3 SLCO1B1	1.25e-04	12	32	2	ctd:C057619
Drug	Phalloidine	SLCO1B3 SLCO1B1	1.48e-04	13	32	2	ctd:D010590
Drug	AG-013608 [351320-38-2]; Up 200; 10uM; PC3; HT_HG-U133A	SEMA3F TCF4 SVEP1 ZNF646	1.62e-04	197	32	4	6400_UP
Drug	Esculin Hydrate [531-75-9]; Up 200; 11.8uM; PC3; HT_HG-U133A	TLK1 ANGPT1 SLCO1B1 SVEP1	1.62e-04	197	32	4	6310_UP
Drug	AC1Q7BBT	SLCO1B3 SLCO1B1	1.72e-04	14	32	2	CID000086545
Disease	Rotor syndrome	SLCO1B3 SLCO1B1	1.07e-06	2	31	2	cv:C0220991
Disease	HYPERBILIRUBINEMIA, ROTOR TYPE, DIGENIC	SLCO1B3 SLCO1B1	1.07e-06	2	31	2	C4016905
Disease	HYPERBILIRUBINEMIA, ROTOR TYPE	SLCO1B3 SLCO1B1	1.07e-06	2	31	2	237450
Disease	Rotor Syndrome	SLCO1B3 SLCO1B1	1.07e-06	2	31	2	C0220991
Disease	bilirubin metabolic disorder (implicated_via_orthology)	SLCO1B3 SLCO1B1	1.07e-05	5	31	2	DOID:2741 (implicated_via_orthology)
Disease	intraocular pressure measurement	PCSK5 SEMA3F BAMBI TCF4 EFEMP1 ANGPT1	1.31e-05	509	31	6	EFO_0004695
Disease	bilirubin metabolic disorder (is_implicated_in)	SLCO1B3 SLCO1B1	1.60e-05	6	31	2	DOID:2741 (is_implicated_in)
Disease	deoxycholic acid glucuronide measurement	SLCO1B3 SLCO1B1	2.98e-05	8	31	2	EFO_0800575
Disease	hexadecenedioate (C16:1-DC) measurement	SLCO1B3 SLCO1B1	3.83e-05	9	31	2	EFO_0800562
Disease	X-21467 measurement	SLCO1B3 SLCO1B1	3.83e-05	9	31	2	EFO_0020007
Disease	response to statin, myopathy	RASGRF2 SLCO1B1	5.84e-05	11	31	2	EFO_0004145, GO_0036273
Disease	glycochenodeoxycholate glucuronide (1) measurement	SLCO1B3 SLCO1B1	8.27e-05	13	31	2	EFO_0800474
Disease	Malignant neoplasm of breast	NRIP1 EFEMP1 BRCA1 RASGRF2 SLCO1B1 ROR1 ZNF646	1.01e-04	1074	31	7	C0006142
Disease	response to statin, LDL cholesterol change measurement	SLCO1B1 LPA	1.11e-04	15	31	2	EFO_0007804, GO_0036273
Disease	Mammary Carcinoma, Human	NRIP1 EFEMP1 BRCA1 SLCO1B1 ROR1	2.03e-04	525	31	5	C4704874
Disease	Mammary Neoplasms, Human	NRIP1 EFEMP1 BRCA1 SLCO1B1 ROR1	2.03e-04	525	31	5	C1257931
Disease	Mammary Neoplasms	NRIP1 EFEMP1 BRCA1 SLCO1B1 ROR1	2.06e-04	527	31	5	C1458155
Disease	Breast Carcinoma	NRIP1 EFEMP1 BRCA1 SLCO1B1 ROR1	2.27e-04	538	31	5	C0678222
Disease	Schizophrenia	ERVK-8 CACNA1F NRIP1 TCF4 BRCA1 RAI1	2.74e-04	883	31	6	C0036341
Disease	Animal Mammary Neoplasms	EFEMP1 BRCA1 RASGRF2	4.44e-04	142	31	3	C0024667
Disease	Mammary Carcinoma, Animal	EFEMP1 BRCA1 RASGRF2	4.44e-04	142	31	3	C1257925
Disease	Mammary Neoplasms, Experimental	EFEMP1 BRCA1 RASGRF2	5.74e-04	155	31	3	C0024668
Disease	Carcinomatosis	EFEMP1 BRCA1 RASGRF2	6.64e-04	163	31	3	C0205699
Disease	Carcinoma, Spindle-Cell	EFEMP1 BRCA1 RASGRF2	6.64e-04	163	31	3	C0205697
Disease	Undifferentiated carcinoma	EFEMP1 BRCA1 RASGRF2	6.64e-04	163	31	3	C0205698
Disease	Anaplastic carcinoma	EFEMP1 BRCA1 RASGRF2	6.64e-04	163	31	3	C0205696
Disease	Carcinoma	EFEMP1 BRCA1 RASGRF2	6.76e-04	164	31	3	C0007097
Disease	atherosclerosis (is_marker_for)	LPA PARP15	6.95e-04	37	31	2	DOID:1936 (is_marker_for)
Disease	neuroimaging measurement	TCF4 ANGPT1 BRCA1 UTP4 ROR1 RAI1	7.54e-04	1069	31	6	EFO_0004346
Disease	open-angle glaucoma	EFEMP1 ANGPT1 SVEP1	1.05e-03	191	31	3	EFO_0004190

Protein segments in the cluster

Peptide	Gene	Start	Entry
PRGQFYHNCSGQTQS	ERVK-18	156	O42043
APRGQFYHNCSGQTQ	ERVK-19	266	O71037
APRGQFYHNCSGQTQ	ERVK-8	266	Q902F8
RGYHGLGPQRSRQQQ	EAPP	156	Q56P03
PENSGRRYNRIQHGQ	ANGPT1	26	Q15389
YCNQARGSPARVNSN	RAI1	531	Q7Z5J4
GTYHRGRNSGPNRAQ	CACNA1F	1821	O60840
VPYVNQHGFNRSCAG	PARP15	566	Q460N3
QAGHPFQQRCAQSAY	MTMR9	371	Q96QG7
YNQLCENTPGGHRCS	HMCN2	4726	Q8NDA2
SYGRESNLQGCHQQS	TCF4	111	P15884
ASGCSDNPNRHVNYL	PCSK5	491	Q92824
CGQYSAQRSQRPHQG	LECT2	41	O14960
CQSNGPVLNTHTYQG	NRIP1	61	P48552
APRGQFYHNCSGQTQ	ERVK-7	1026	P63135
HSCSGSLQNRNYPSQ	BRCA1	1511	P38398
SGQGNRYQHDGSRNL	BAMBI	121	Q13145
PRGQFYHNCSGQTQS	ERVK-24	156	P61566
APRGQFYHNCSGQTQ	ERVK-25	266	P61570
APRGQFYHNCSGQTQ	ERVK-6	266	Q69384
PRGQFYHNCSGQTQS	ERVK-7	156	P61567
QRPGVQECYHGNGQS	LPA	591	P08519
PRGQFYHNCSGQTQS	ERVK-21	266	P61565
PRGQFYHNCSGQTQS	ERVK-5	156	Q9HDB8
NYTGQCPSGIRAQND	HYAL1	216	Q12794
APRGQFYHNCSGQTQ	HERVK_113	266	Q902F9
SNPSHRIQCAAGYEQ	EFEMP1	151	Q12805
PSGIRCVAYNNQSNR	UTP4	16	Q969X6
HGNPIRQCRGFNSNA	SEMA3F	591	Q13275
YRQPGGQTADNAHCS	RASGRF2	861	O14827
SQCPGHQATPRQRYQ	HEPH	716	Q9BQS7
PCHNSGTCQQLGRGY	SVEP1	1201	Q4LDE5
GLQNRNYSAHLGECP	SLCO1B1	511	Q9Y6L6
NGGHSYCRNPGNQKE	ROR1	356	Q01973
QCLYGRKPFGHNQSQ	TLK1	666	Q9UKI8
GLQNRNYSAHLGECP	SLCO1B3	511	Q9NPD5
QQCGRGYRHPGSLVN	ZNF646	51	O15015
ISCRPQIHISNNYGN	ZNF808	196	Q8N4W9
NFQGVYHPGDNRSCN	TEX13C	301	A0A0J9YWL9
SCRPKTHISNNYGNN	ZNF813	181	Q6ZN06
YGNRGHNQPCLLVGS	CAD	271	P27708
NVAPRSNQRCNPGGY	ZNF516-DT	51	Q6ZTR6
QHICRNNLYPNSSPG	VN1R2	296	Q8NFZ6