Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionaspartic-type endopeptidase activity

ERVK-6 ERVK-7 ERVK-21 ERVK-9 ERVK-10 CNTNAP5 ERVK-8 ERVK-24

1.38e-10371388GO:0004190
GeneOntologyMolecularFunctionaspartic-type peptidase activity

ERVK-6 ERVK-7 ERVK-21 ERVK-9 ERVK-10 CNTNAP5 ERVK-8 ERVK-24

1.74e-10381388GO:0070001
GeneOntologyMolecularFunctionendopeptidase activity

ERVK-6 ADAMTS19 TMPRSS15 PRSS8 ADAM19 PRSS22 ERVK-7 ERVK-21 ERVK-9 ERVK-10 CNTNAP5 ERVK-8 PRSS45P ADAM17 ERVK-24

3.03e-0743013815GO:0004175
GeneOntologyMolecularFunctionpeptidase activity

ERVK-6 ADAMTS19 TMPRSS15 PRSS8 ADAM19 USP28 PRSS22 ERVK-7 ERVK-21 ERVK-9 ERVK-10 CNTNAP5 USP32 ERVK-8 PRSS45P ADAM17 ERVK-24 COPS6

6.17e-0765413818GO:0008233
GeneOntologyMolecularFunctionRNA-DNA hybrid ribonuclease activity

ERVK-6 ERVK-7 ERVK-10 ERVK-8

6.94e-07111384GO:0004523
GeneOntologyMolecularFunctionRNA-directed DNA polymerase activity

ERVK-6 ERVK-7 ERVK-10 ERVK-8

2.07e-06141384GO:0003964
GeneOntologyMolecularFunctionnucleotidyltransferase activity

ERVK-6 POLR2B ERVK-7 ERVK-10 POLR3B SELENOO ERVK-8 UAP1L1

1.08e-051521388GO:0016779
GeneOntologyMolecularFunctionRNA stem-loop binding

ERVK-6 ERVK-7 ERVK-10 ERVK-8

1.19e-05211384GO:0035613
GeneOntologyMolecularFunctiontransferase activity, transferring phosphorus-containing groups

CDK20 ERVK-6 HK3 POLR2B PBK DGKQ ERVK-7 ERVK-10 PMS2P11 MAP3K5 NEK4 POLR3B NEK5 SELENOO ERVK-8 AKT1 ROS1 UAP1L1

8.33e-0593813818GO:0016772
GeneOntologyMolecularFunctionarylsulfatase activity

STS ARSD ARSF

1.11e-04141383GO:0004065
GeneOntologyMolecularFunctionRNA endonuclease activity, producing 5'-phosphomonoesters

ERVK-6 ERVK-7 ERVK-10 ERVK-8

1.21e-04371384GO:0016891
GeneOntologyMolecularFunctionDNA polymerase activity

ERVK-6 ERVK-7 ERVK-10 ERVK-8

1.34e-04381384GO:0034061
GeneOntologyMolecularFunctionribonucleoside binding

POLR2B POLR3B

1.42e-0431382GO:0032549
GeneOntologyMolecularFunctionsulfuric ester hydrolase activity

STS ARSD ARSF

2.05e-04171383GO:0008484
GeneOntologyMolecularFunctionmetalloendopeptidase activity involved in amyloid precursor protein catabolic process

ADAM19 ADAM17

2.82e-0441382GO:1902945
GeneOntologyMolecularFunctionendonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters

ERVK-6 ERVK-7 ERVK-10 ERVK-8

2.85e-04461384GO:0016893
GeneOntologyMolecularFunctionABC-type transporter activity

ABCA12 ATP13A1 ABCB4 ATP13A3

3.64e-04491384GO:0140359
GeneOntologyMolecularFunctionphosphotyrosine residue binding

IRS1 PFN1 PTPN11 PLCG2

4.24e-04511384GO:0001784
GeneOntologyMolecularFunctionstructural molecule activity

ERVK-6 KRT3 ACTBL2 LAMA3 ERVK-7 ERVK-21 ERVK-9 ERVK-10 APOE JUP FBLN2 HMCN2 ACAN ERVK-8 ERVK-24 BFSP2

4.43e-0489113816GO:0005198
GeneOntologyMolecularFunctioncatalytic activity, acting on RNA

ERVK-6 POLR2B ERVK-7 ERVK-10 NARS2 PARS2 POLR3B EXOSC6 ERVK-8 AQR

6.52e-0441713810GO:0140098
GeneOntologyMolecularFunctionATPase-coupled transmembrane transporter activity

ATP6V1A ABCA12 ATP13A1 ABCB4 ATP13A3

9.63e-041091385GO:0042626
GeneOntologyMolecularFunctionhyaluronic acid binding

STAB2 STAB1 ACAN

1.03e-03291383GO:0005540
GeneOntologyMolecularFunctionphosphoprotein binding

IRS1 PFN1 PTPN11 PLCG2 NOS1

1.32e-031171385GO:0051219
GeneOntologyMolecularFunctionprotein phosphorylated amino acid binding

IRS1 PFN1 PTPN11 PLCG2

1.33e-03691384GO:0045309
GeneOntologyMolecularFunctionlipoprotein particle binding

STAB2 APOE STAB1

1.80e-03351383GO:0071813
GeneOntologyMolecularFunctionprotein-lipid complex binding

STAB2 APOE STAB1

1.80e-03351383GO:0071814
GeneOntologyMolecularFunctionRNA endonuclease activity

ERVK-6 ERVK-7 ERVK-10 ERVK-8

2.20e-03791384GO:0004521
GeneOntologyMolecularFunctionnucleoside binding

POLR2B POLR3B

2.50e-03111382GO:0001882
GeneOntologyMolecularFunctionRNA nuclease activity

ERVK-6 ERVK-7 ERVK-10 EXOSC6 ERVK-8

2.56e-031361385GO:0004540
GeneOntologyBiologicalProcessDNA integration

ERVK-6 ERVK-7 ERVK-10 ERVK-8

1.23e-06131364GO:0015074
GeneOntologyBiologicalProcesscell-cell fusion

NPHS1 ERVK-6 ERVK-21 ERVK-9 NFATC2 ERVK-8 NOS1

1.49e-06851367GO:0140253
GeneOntologyBiologicalProcesssyncytium formation by plasma membrane fusion

NPHS1 ERVK-6 ERVK-21 ERVK-9 NFATC2 ERVK-8 NOS1

1.49e-06851367GO:0000768
GeneOntologyBiologicalProcesssyncytium formation

NPHS1 ERVK-6 ERVK-21 ERVK-9 NFATC2 ERVK-8 NOS1

2.04e-06891367GO:0006949
GeneOntologyBiologicalProcessviral process

ERVK-6 RCC1 ZNFX1 ERVK-7 ERVK-21 ERVK-9 ERVK-10 APOE PFN1 ERVK-8 AKT1 ERVK-24 ATG16L2

1.25e-0546413613GO:0016032
GeneOntologyCellularComponenthemidesmosome

LAMA3 ITGB4 JUP

4.47e-05111383GO:0030056
GeneOntologyCellularComponentbasement membrane

NPHS1 LAMA3 CCDC80 ITGB4 HMCN2 ACAN

1.60e-041221386GO:0005604
GeneOntologyCellularComponentcollagen-containing extracellular matrix

NPHS1 ADAM19 ANGPT2 LAMA3 CCDC80 APOE ITGB4 FBLN2 HMCN2 SEMA6D MEGF6 ACAN

2.10e-0453013812GO:0062023
GeneOntologyCellularComponentextracellular matrix

NPHS1 ADAMTS19 ADAM19 ANGPT2 LAMA3 CCDC80 APOE ITGB4 FBLN2 HMCN2 SEMA6D MEGF6 ACAN

4.13e-0465613813GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

NPHS1 ADAMTS19 ADAM19 ANGPT2 LAMA3 CCDC80 APOE ITGB4 FBLN2 HMCN2 SEMA6D MEGF6 ACAN

4.25e-0465813813GO:0030312
GeneOntologyCellularComponentmembrane raft

PRSS8 IRS1 ADCY1 ABCB4 PTPN11 ERLIN2 ADAM17 PLCG2 NOS1

6.85e-043621389GO:0045121
GeneOntologyCellularComponentmembrane microdomain

PRSS8 IRS1 ADCY1 ABCB4 PTPN11 ERLIN2 ADAM17 PLCG2 NOS1

7.13e-043641389GO:0098857
DomainEGF_1

STAB2 ADAM19 LAMA3 CRTAC1 ITGB4 STAB1 CNTNAP5 FBLN2 HMCN2 MEGF6

1.28e-0525513110PS00022
DomainEGF-like_CS

STAB2 ADAM19 LAMA3 CRTAC1 ITGB4 STAB1 FBLN2 HMCN2 MEGF6 ADAM17

1.57e-0526113110IPR013032
DomainEGF_2

STAB2 ADAM19 LAMA3 CRTAC1 ITGB4 STAB1 CNTNAP5 FBLN2 HMCN2 MEGF6

1.79e-0526513110PS01186
DomainRNA_pol_Rpb2_4

POLR2B POLR3B

4.88e-0521312PF04566
DomainRNA_pol_Rpb2_4

POLR2B POLR3B

4.88e-0521312IPR007646
DomainEGF_extracell

STAB2 ADAM19 ITGB4 STAB1 MEGF6

6.30e-05601315IPR013111
DomainEGF_2

STAB2 ADAM19 ITGB4 STAB1 MEGF6

6.30e-05601315PF07974
DomainEGF-like_dom

STAB2 ADAM19 LAMA3 CRTAC1 STAB1 CNTNAP5 FBLN2 HMCN2 MEGF6

6.63e-052491319IPR000742
DomainEGF_Lam

STAB2 LAMA3 STAB1 MEGF6

1.02e-04351314SM00180
DomainGrowth_fac_rcpt_

STAB2 LAMA3 STAB1 FBLN2 IGFBP2 HMCN2 MEGF6

1.16e-041561317IPR009030
DomainLaminin_EGF

STAB2 LAMA3 STAB1 MEGF6

1.42e-04381314IPR002049
Domain-

POLR2B POLR3B

1.46e-04313122.40.270.10
DomainRNA_pol_RPB2_OB-fold

POLR2B POLR3B

1.46e-0431312IPR014724
DomainRNA_pol_bsu_CS

POLR2B POLR3B

1.46e-0431312IPR007121
DomainDNA-dir_RNA_pol_su2_6

POLR2B POLR3B

1.46e-0431312IPR007120
DomainRNA_pol_Rpb2_7

POLR2B POLR3B

1.46e-0431312PF04560
DomainRNA_pol_Rpb2_2

POLR2B POLR3B

1.46e-0431312PF04561
DomainRNA_pol_Rpb2_5

POLR2B POLR3B

1.46e-0431312PF04567
DomainRNA_pol_Rpb2_1

POLR2B POLR3B

1.46e-0431312PF04563
DomainRNA_pol_Rpb2_3

POLR2B POLR3B

1.46e-0431312PF04565
DomainRNA_pol_Rpb2_5

POLR2B POLR3B

1.46e-0431312IPR007647
DomainRNA_pol_Rpb2_3

POLR2B POLR3B

1.46e-0431312IPR007645
DomainRNA_pol_bsu_protrusion

POLR2B POLR3B

1.46e-0431312IPR007644
DomainRNA_pol_Rpb2_2

POLR2B POLR3B

1.46e-0431312IPR007642
DomainRNA_pol_Rpb2_7

POLR2B POLR3B

1.46e-0431312IPR007641
Domain-

POLR2B POLR3B

1.46e-04313122.40.50.150
DomainRNA_POL_BETA

POLR2B POLR3B

1.46e-0431312PS01166
Domain-

POLR2B POLR3B

1.46e-04313123.90.1110.10
DomainDNA-dir_RNA_pol_su2

POLR2B POLR3B

1.46e-0431312IPR015712
DomainRNA_pol_Rpb2_6

POLR2B POLR3B

1.46e-0431312PF00562
DomainSulfatase_CS

STS ARSD ARSF

1.77e-04161313IPR024607
DomainSULFATASE_1

STS ARSD ARSF

2.13e-04171313PS00523
DomainSULFATASE_2

STS ARSD ARSF

2.13e-04171313PS00149
DomainEGF_CA

STAB2 CRTAC1 STAB1 FBLN2 HMCN2 MEGF6

2.21e-041221316SM00179
DomainEGF-like_Ca-bd_dom

STAB2 CRTAC1 STAB1 FBLN2 HMCN2 MEGF6

2.41e-041241316IPR001881
DomainSulfatase

STS ARSD ARSF

2.55e-04181313PF00884
DomainSulfatase_N

STS ARSD ARSF

2.55e-04181313IPR000917
DomainEGF_3

STAB2 ADAM19 CRTAC1 STAB1 CNTNAP5 FBLN2 HMCN2 MEGF6

2.56e-042351318PS50026
DomainFAS1

STAB2 STAB1

2.90e-0441312SM00554
DomainFAS1_domain

STAB2 STAB1

2.90e-0441312IPR000782
Domain-

STAB2 STAB1

2.90e-04413122.30.180.10
DomainFAS1

STAB2 STAB1

2.90e-0441312PS50213
DomainFasciclin

STAB2 STAB1

2.90e-0441312PF02469
DomainFA58C

DCBLD1 CNTNAP5 DCBLD2

4.09e-04211313SM00231
DomainFA58C_3

DCBLD1 CNTNAP5 DCBLD2

4.09e-04211313PS50022
DomainFA58C_1

DCBLD1 CNTNAP5 DCBLD2

4.09e-04211313PS01285
DomainFA58C_2

DCBLD1 CNTNAP5 DCBLD2

4.09e-04211313PS01286
DomainP-type_TPase_V

ATP13A1 ATP13A3

4.82e-0451312IPR006544
DomainF5_F8_type_C

DCBLD1 CNTNAP5 DCBLD2

6.13e-04241313PF00754
DomainFA58C

DCBLD1 CNTNAP5 DCBLD2

6.13e-04241313IPR000421
DomainLCCL

DCBLD1 DCBLD2

7.19e-0461312PS50820
DomainFAD_binding_1

POR NOS1

7.19e-0461312PF00667
Domain-

POR NOS1

7.19e-04613121.20.990.10
DomainLCCL

DCBLD1 DCBLD2

7.19e-0461312SM00603
DomainLCCL

DCBLD1 DCBLD2

7.19e-0461312PF03815
DomainFAD-binding_1

POR NOS1

7.19e-0461312IPR003097
DomainLCCL

DCBLD1 DCBLD2

7.19e-0461312IPR004043
Domain-

DCBLD1 DCBLD2

7.19e-04613122.170.130.20
DomainNADPH_Cyt_P450_Rdtase_dom3

POR NOS1

7.19e-0461312IPR023173
DomainEGF_LAM_2

STAB2 LAMA3 STAB1

1.19e-03301313PS50027
DomainEGF_LAM_1

STAB2 LAMA3 STAB1

1.19e-03301313PS01248
DomainAlkaline_phosphatase_core

STS ARSD ARSF

1.31e-03311313IPR017850
DomainAlkaline_Pase-like_a/b/a

STS ARSD ARSF

1.31e-03311313IPR017849
Domain-

STS ARSD ARSF

1.31e-033113133.40.720.10
DomainFlavodoxin/NO_synth

POR NOS1

1.33e-0381312IPR008254
DomainFlavdoxin-like

POR NOS1

1.33e-0381312IPR001094
DomainFLAVODOXIN_LIKE

POR NOS1

1.33e-0381312PS50902
DomainFlavodoxin_1

POR NOS1

1.33e-0381312PF00258
DomainLaminin_EGF

LAMA3 STAB1 MEGF6

1.87e-03351313PF00053
Domain-

POR NOS1

2.12e-031013123.40.50.360
DomainFlavoprotein-like_dom

POR NOS1

2.12e-03101312IPR029039
DomainFlavoprot_Pyr_Nucl_cyt_Rdtase

POR NOS1

2.12e-03101312IPR001709
DomainPep_M12B_propep

ADAMTS19 ADAM19 ADAM17

2.56e-03391313PF01562
DomainPeptidase_M12B_N

ADAMTS19 ADAM19 ADAM17

2.56e-03391313IPR002870
DomainPTBI

IRS1 DOK4

2.58e-03111312SM00310
DomainGFP-like

STAB2 STAB1

2.58e-03111312IPR023413
Domain-

STAB2 STAB1

2.58e-031113122.40.155.10
DomainDISINTEGRIN_1

ADAMTS19 ADAM19 ADAM17

2.76e-03401313PS00427
DomainReprolysin

ADAMTS19 ADAM19 ADAM17

2.76e-03401313PF01421
DomainADAM_MEPRO

ADAMTS19 ADAM19 ADAM17

2.76e-03401313PS50215
DomainDISINTEGRIN_2

ADAMTS19 ADAM19 ADAM17

2.76e-03401313PS50214
DomainPeptidase_M12B

ADAMTS19 ADAM19 ADAM17

2.76e-03401313IPR001590
DomainIg_V-set

BOC NPHS1 MCAM ROBO2 CD79B VCAM1

2.82e-031991316IPR013106
DomainCYSTEINE_SWITCH

ADAMTS19 ADAM19 ADAM17

2.96e-03411313PS00546
DomainDisintegrin_dom

ADAMTS19 ADAM19 ADAM17

2.96e-03411313IPR001762
DomainOxRdtase_FAD/NAD-bd

POR NOS1

3.08e-03121312IPR001433
DomainEGF_dom

STAB2 STAB1

3.08e-03121312IPR024731
DomainIRS_PTB

IRS1 DOK4

3.08e-03121312PS51064
DomainNAD_binding_1

POR NOS1

3.08e-03121312PF00175
DomainEGF_3

STAB2 STAB1

3.08e-03121312PF12947
DomainEGF_CA

CRTAC1 FBLN2 HMCN2 MEGF6

3.15e-03861314PF07645
DomainPept_M10_metallopeptidase

ADAMTS19 ADAM19 ADAM17

3.39e-03431313IPR001818
DomainPH_DOMAIN

ARHGEF28 NET1 IRS1 DOK4 AKT1 PLCG2 PHLPP2

3.56e-032791317PS50003
DomainLink_dom

STAB2 STAB1

3.62e-03131312IPR000538
DomainXlink

STAB2 STAB1

3.62e-03131312PF00193
DomainLINK_2

STAB2 STAB1

3.62e-03131312PS50963
DomainLINK

STAB2 STAB1

3.62e-03131312SM00445
DomainLINK_1

STAB2 STAB1

3.62e-03131312PS01241
DomainIRS

IRS1 DOK4

4.20e-03141312PF02174
DomainIRS_PTB

IRS1 DOK4

4.20e-03141312IPR002404
PathwayWP_ALPHA_6_BETA_4_SIGNALING

LAMA3 IRS1 ITGB4 PTPN11 AKT1

3.81e-06331035M39503
Pubmed

Many human endogenous retrovirus K (HERV-K) proviruses are unique to humans.

ERVK-6 ERVK-7 ERVK-10 ERVK-24

2.59e-104141410469592
Pubmed

A revised nomenclature for transcribed human endogenous retroviral loci.

ERVK-6 ERVK-7 ERVK-21 ERVK-9 ERVK-10 ERVK-8 ERVK-24

1.18e-0794141721542922
Pubmed

Genomewide screening for fusogenic human endogenous retrovirus envelopes identifies syncytin 2, a gene conserved on primate evolution.

ERVK-6 ERVK-21 ERVK-9 ERVK-8

1.25e-0712141414557543
Pubmed

Targeting of Scavenger Receptors Stabilin-1 and Stabilin-2 Ameliorates Atherosclerosis by a Plasma Proteome Switch Mediating Monocyte/Macrophage Suppression.

STAB2 APOE STAB1

2.60e-074141336325910
Pubmed

Quantitation of HERV-K env gene expression and splicing in human breast cancer.

ERVK-6 ERVK-7 ERVK-21

6.48e-075141312629516
Pubmed

Expression patterns of transcribed human endogenous retrovirus HERV-K(HML-2) loci in human tissues and the need for a HERV Transcriptome Project.

ERVK-21 ERVK-9 ERVK-10 ERVK-24

7.58e-0718141418664271
Pubmed

Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins.

MCAM LAMA3 APOE FBLN2 HMCN2 ACAN SERPIND1

2.35e-06146141727068509
Pubmed

A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.

ATP6V1A REPS1 KBTBD6 POLR2B PBK RAB3GAP1 POLR3B GTF3C2 WDR6 COPS6 TNPO3 AQR

3.28e-065601411235241646
Pubmed

Genetics of lymphatic anomalies.

PTPN11 AKT1 FOXC2

3.60e-068141324590274
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

ENGASE TRPM4 TBC1D9B REPS1 ATP13A1 DGKQ IRS1 ITGB4 MAP3K5 PCNX2 MEGF6 DOK4 EXOSC6 AKT1 DOT1L TNPO3

1.13e-0511051411635748872
Pubmed

The COOH-terminal tyrosine phosphorylation sites on IRS-1 bind SHP-2 and negatively regulate insulin signaling.

IRS1 PTPN11

1.63e-05214129756938
Pubmed

Reduction of Stabilin-2 Contributes to a Protection Against Atherosclerosis.

STAB2 APOE

1.63e-052141235360009
Pubmed

FOXC2 controls Ang-2 expression and modulates angiogenesis, vascular patterning, remodeling, and functions in adipose tissue.

ANGPT2 FOXC2

1.63e-052141218621714
Pubmed

Genetic Evidence Supports a Major Role for Akt1 in VSMCs During Atherogenesis.

APOE AKT1

1.63e-052141225868464
Pubmed

CD146 promotes malignant progression of breast phyllodes tumor through suppressing DCBLD2 degradation and activating the AKT pathway.

MCAM DCBLD2

1.63e-052141237856423
Pubmed

SNP rs9387478 at ROS1-DCBLD1 Locus is Significantly Associated with Lung Cancer Risk and Poor Survival in Indian Population.

DCBLD1 ROS1

1.63e-052141236308382
Pubmed

PARS2 and NARS2 mutations in infantile-onset neurodegenerative disorder.

NARS2 PARS2

1.63e-052141228077841
Pubmed

rac regulates its effector phospholipase Cgamma2 through interaction with a split pleckstrin homology domain.

AKT1 PLCG2

1.63e-052141218728011
Pubmed

Stabilin-1 and stabilin-2 are both directed into the early endocytic pathway in hepatic sinusoidal endothelium via interactions with clathrin/AP-2, independent of ligand binding.

STAB2 STAB1

1.63e-052141215572036
Pubmed

Endothelial nitric oxide synthase (eNOS) S1176 phosphorylation status governs atherosclerotic lesion formation.

APOE AKT1

1.63e-052141238034389
Pubmed

Strain-dependent embryonic lethality and exaggerated vascular remodeling in heparin cofactor II-deficient mice.

APOE SERPIND1

1.63e-052141217549254
Pubmed

FEEL-1, a novel scavenger receptor with in vitro bacteria-binding and angiogenesis-modulating activities.

STAB2 STAB1

1.63e-052141212077138
Pubmed

Macrophages retain hematopoietic stem cells in the spleen via VCAM-1.

APOE VCAM1

1.63e-052141225800955
Pubmed

Akt1 regulates vascular smooth muscle cell apoptosis through FoxO3a and Apaf1 and protects against arterial remodeling and atherosclerosis.

APOE AKT1

1.63e-052141225234814
Pubmed

The Role of Dot1l in Prenatal and Postnatal Murine Chondrocytes and Trabecular Bone.

ACAN DOT1L

1.63e-052141232083237
Pubmed

Whole exome sequencing reveals mutations in NARS2 and PARS2, encoding the mitochondrial asparaginyl-tRNA synthetase and prolyl-tRNA synthetase, in patients with Alpers syndrome.

NARS2 PARS2

1.63e-052141225629079
Pubmed

Reciprocal regulation of MelCAM and AKT in human melanoma.

MCAM AKT1

1.63e-052141214534536
Pubmed

Identifying Stabilin-1 and Stabilin-2 Double Knockouts in Reproduction and Placentation: A Descriptive Study.

STAB2 STAB1

1.63e-052141233008099
Pubmed

The NIMA kinase: a mitotic regulator in Aspergillus nidulans and vertebrate cells.

NEK4 NEK5

1.63e-05214129552363
Pubmed

Deficiency of liver sinusoidal scavenger receptors stabilin-1 and -2 in mice causes glomerulofibrotic nephropathy via impaired hepatic clearance of noxious blood factors.

STAB2 STAB1

1.63e-052141221293057
Pubmed

Low insulin-like growth factor binding protein-2 expression is responsible for increased insulin receptor substrate-1 phosphorylation in mesangial cells from mice susceptible to glomerulosclerosis.

IRS1 IGFBP2

1.63e-052141216556765
Pubmed

The DCBLD receptor family: emerging signaling roles in development, homeostasis and disease.

DCBLD1 DCBLD2

1.63e-052141230902898
Pubmed

Role of SH-PTP2, a protein-tyrosine phosphatase with Src homology 2 domains, in insulin-stimulated Ras activation.

IRS1 PTPN11

1.63e-05214127935386
Pubmed

Stimulated shedding of vascular cell adhesion molecule 1 (VCAM-1) is mediated by tumor necrosis factor-alpha-converting enzyme (ADAM 17).

ADAM17 VCAM1

1.63e-052141212878595
Pubmed

Integrin beta4 attenuates SHP-2 and MAPK signaling and reduces human lung endothelial inflammatory responses.

ITGB4 PTPN11

1.63e-052141220512931
Pubmed

Insulin receptor substrate 1 overexpression promotes survival of glioblastoma cells through AKT1 activation.

IRS1 AKT1

1.63e-052141232337956
Pubmed

Akt1 isoform modulates phenotypic conversion of vascular smooth muscle cells.

APOE AKT1

1.63e-052141225201081
Pubmed

Activation of the SH2-containing protein tyrosine phosphatase, SH-PTP2, by phosphotyrosine-containing peptides derived from insulin receptor substrate-1.

IRS1 PTPN11

1.63e-05214127513703
Pubmed

Tenomodulin variants, APOE and Alzheimer's disease in a Finnish case-control cohort.

APOE TNMD

1.63e-052141219524323
Pubmed

Apoptosis signal-regulating kinase 1 deficiency accelerates hyperlipidemia-induced atheromatous plaques via suppression of macrophage apoptosis.

APOE MAP3K5

1.63e-052141221527753
Pubmed

FEEL-1 and FEEL-2 are endocytic receptors for advanced glycation end products.

STAB2 STAB1

1.63e-052141212473645
Pubmed

Enhanced expression of TACE contributes to elevated levels of sVCAM-1 in endometriosis.

ADAM17 VCAM1

1.63e-052141230395261
Pubmed

Loss of Akt1 leads to severe atherosclerosis and occlusive coronary artery disease.

APOE AKT1

1.63e-052141218054314
Pubmed

Association of a NOS1 promoter repeat with Alzheimer's disease.

APOE NOS1

1.63e-052141217418914
Pubmed

AKT has an anti-apoptotic role in ABCA12-deficient keratinocytes.

ABCA12 AKT1

1.63e-052141221633372
Pubmed

In vivo intra-articular contrast enhanced ÎĽCT imaging of mouse knee cartilage.

ACAN DOT1L

1.63e-052141236436817
Pubmed

Mechanism for phosphatidylserine-dependent erythrophagocytosis in mouse liver.

STAB2 STAB1

1.63e-052141221427291
Pubmed

Phenotypical and biochemical characterization of murine psoriasiform and fibrotic skin disease models in Stabilin-deficient mice.

STAB2 STAB1

1.63e-052141238946049
Pubmed

Adhesion of monocytes to arterial endothelium and initiation of atherosclerosis are critically dependent on vascular cell adhesion molecule-1 gene dosage.

APOE VCAM1

1.63e-052141211597942
Pubmed

Cardiomyocyte cohesion is increased after ADAM17 inhibition.

JUP ADAM17

1.63e-052141236733457
Pubmed

Phosphorylation of insulin receptor substrate-1 (IRS-1) by protein kinase B positively regulates IRS-1 function.

IRS1 AKT1

1.63e-052141210497255
Pubmed

Scavenging Endothelium of Pancreatic Islets: Differential Expression of Stabilin-1 and Stabilin-2 in Mice and Humans.

STAB2 STAB1

1.63e-052141227977633
Pubmed

Exploring the transcriptomic network of multi-ligand scavenger receptor Stabilin-1- and Stabilin-2-deficient liver sinusoidal endothelial cells.

STAB2 STAB1

1.63e-052141233130055
Pubmed

The insulin receptor substrate 1 associates with the SH2-containing phosphotyrosine phosphatase Syp.

IRS1 PTPN11

1.63e-05214128505282
Pubmed

Inhibition of protein kinase Akt1 by apoptosis signal-regulating kinase-1 (ASK1) is involved in apoptotic inhibition of regulatory volume increase.

MAP3K5 AKT1

1.63e-052141220048146
Pubmed

Akt phosphorylates and negatively regulates apoptosis signal-regulating kinase 1.

MAP3K5 AKT1

1.63e-052141211154276
Pubmed

Cardiac muscle protein catabolism in diabetes mellitus: activation of the ubiquitin-proteasome system by insulin deficiency.

IRS1 AKT1

1.63e-052141218653708
Pubmed

Stabilin-1 and -2 constitute a novel family of fasciclin-like hyaluronan receptor homologues.

STAB2 STAB1

1.63e-052141211829752
Pubmed

Regulation of insulin receptor substrate 1 (IRS-1)/AKT kinase-mediated insulin signaling by O-Linked beta-N-acetylglucosamine in 3T3-L1 adipocytes.

IRS1 AKT1

1.63e-052141220018868
Pubmed

Nongenomic, endothelium-independent effects of estrogen on human coronary smooth muscle are mediated by type I (neuronal) NOS and PI3-kinase-Akt signaling.

AKT1 NOS1

1.63e-052141217351066
Pubmed

Accelerated atheromatous lesions in mouse hearts transplanted to apolipoprotein-E-deficient recipients.

APOE VCAM1

1.63e-05214128686767
Pubmed

Association of Differentially Altered Liver Fibrosis with Deposition of TGFBi in Stabilin-Deficient Mice.

STAB2 STAB1

1.63e-052141237446152
Pubmed

YAP and TAZ maintain PROX1 expression in the developing lymphatic and lymphovenous valves in response to VEGF-C signaling.

ANGPT2 TAFAZZIN FOXC2

1.81e-0513141333060128
Pubmed

Gestational diabetes mellitus induces congenital anomalies of the kidney and urinary tract in mice by altering RET/MAPK/ERK pathway.

ROBO2 AKT1 PLCG2

2.86e-0515141338657443
Pubmed

Shp2 is required for protein kinase C-dependent phosphorylation of serine 307 in insulin receptor substrate-1.

IRS1 PTPN11

4.88e-053141216055440
Pubmed

Curcumin enhances the antitumor effect of ABT-737 via activation of the ROS-ASK1-JNK pathway in hepatocellular carcinoma cells.

MAP3K5 ROS1

4.88e-053141226707143
Pubmed

Regulation of IRS1/Akt insulin signaling by microRNA-128a during myogenesis.

IRS1 AKT1

4.88e-053141223606743
Pubmed

Transmembrane and Coiled-Coil Domain 1 Impairs the AKT Signaling Pathway in Urinary Bladder Urothelial Carcinoma: A Characterization of a Tumor Suppressor.

AKT1 PHLPP2

4.88e-053141228972042
Pubmed

Overexpression of Akt1 upregulates glycogen synthase activity and phosphorylation of mTOR in IRS-1 knockdown HepG2 cells.

IRS1 AKT1

4.88e-053141217721885
Pubmed

Insulin receptor substrates differentially exacerbate insulin-mediated left ventricular remodeling.

IRS1 AKT1

4.88e-053141232213702
Pubmed

The loss of glypican-3 induces alterations in Wnt signaling.

IRS1 AKT1

4.88e-053141215537637
Pubmed

Common polymorphism in the phosphatase PHLPP2 results in reduced regulation of Akt and protein kinase C.

AKT1 PHLPP2

4.88e-053141219324870
Pubmed

miR-451a suppresses papillary thyroid cancer cell proliferation and invasion and facilitates apoptosis through targeting DCBLD2 and AKT1.

AKT1 DCBLD2

4.88e-053141236252912
Pubmed

Vascular cellular adhesion molecule-1 (VCAM-1) expression in mice retinal vessels is affected by both hyperglycemia and hyperlipidemia.

APOE VCAM1

4.88e-053141220856927
Pubmed

MiR-181a Targets PHLPP2 to Augment AKT Signaling and Regulate Proliferation and Apoptosis in Human Keloid Fibroblasts.

AKT1 PHLPP2

4.88e-053141227915346
Pubmed

IKKβ regulates essential functions of the vascular endothelium through kinase-dependent and -independent pathways.

APOE AKT1

4.88e-053141221587235
Pubmed

Oxido-reductive regulation of vascular remodeling by receptor tyrosine kinase ROS1.

APOE ROS1

4.88e-053141225401476
Pubmed

ROS fusion tyrosine kinase activates a SH2 domain-containing phosphatase-2/phosphatidylinositol 3-kinase/mammalian target of rapamycin signaling axis to form glioblastoma in mice.

PTPN11 ROS1

4.88e-053141216885344
Pubmed

Quercetin-induced apoptosis of HT-29 colon cancer cells via inhibition of the Akt-CSN6-Myc signaling axis.

AKT1 COPS6

4.88e-053141227748879
Pubmed

Differential involvement of the microtubule cytoskeleton in insulin receptor substrate 1 (IRS-1) and IRS-2 signaling to AKT determines the response to microtubule disruption in breast carcinoma cells.

IRS1 AKT1

4.88e-053141228320862
Pubmed

Functional studies of Akt isoform specificity in skeletal muscle in vivo; maintained insulin sensitivity despite reduced insulin receptor substrate-1 expression.

IRS1 AKT1

4.88e-053141217021050
Pubmed

Identification by shotgun sequencing, genomic organization, and functional analysis of a fourth arylsulfatase gene (ARSF) from the Xp22.3 region.

ARSD ARSF

4.88e-05314129192838
Pubmed

Direct demonstration of P-selectin- and VCAM-1-dependent mononuclear cell rolling in early atherosclerotic lesions of apolipoprotein E-deficient mice.

APOE VCAM1

4.88e-053141210364560
Pubmed

Nephrin, a transmembrane protein, is involved in pancreatic beta-cell survival signaling.

NPHS1 AKT1

4.88e-053141225448064
Pubmed

TRPM4 regulates Akt/GSK3-β activity and enhances β-catenin signaling and cell proliferation in prostate cancer cells.

TRPM4 AKT1

4.88e-053141228614631
Pubmed

Deletion of tenascin-C gene exacerbates atherosclerosis and induces intraplaque hemorrhage in Apo-E-deficient mice.

APOE VCAM1

4.88e-053141222300502
Pubmed

Inhibition of NADPH oxidase 4 activates apoptosis via the AKT/apoptosis signal-regulating kinase 1 pathway in pancreatic cancer PANC-1 cells.

MAP3K5 AKT1

4.88e-053141216532036
Pubmed

Genome-wide association study on Northern Chinese identifies KLF2, DOT1L and STAB2 associated with systemic lupus erythematosus.

STAB2 DOT1L

4.88e-053141233493351
Pubmed

Dynamic multi-site phosphorylation by Fyn and Abl drives the interaction between CRKL and the novel scaffolding receptors DCBLD1 and DCBLD2.

DCBLD1 DCBLD2

4.88e-053141229025973
Pubmed

PHLPP and a second isoform, PHLPP2, differentially attenuate the amplitude of Akt signaling by regulating distinct Akt isoforms.

AKT1 PHLPP2

4.88e-053141217386267
Pubmed

ROS1 Fusion Mediates Immunogenicity by Upregulation of PD-L1 After the Activation of ROS1-SHP2 Signaling Pathway in Non-Small Cell Lung Cancer.

PTPN11 ROS1

4.88e-053141233324391
Pubmed

Hepatic cytochrome P450 deficiency in mouse models for intrahepatic cholestasis predispose to bile salt-induced cholestasis.

POR ABCB4

4.88e-053141225068656
Pubmed

Expression of LPL in endothelial-intact artery results in lipid deposition and vascular cell adhesion molecule-1 upregulation in both LPL and ApoE-deficient mice.

APOE VCAM1

4.88e-053141217038632
Pubmed

miR-493 Promotes Prostate Cancer Cells Proliferation by Targeting PHLPP2 and Activating Akt Signaling Pathway.

AKT1 PHLPP2

4.88e-053141230868840
Pubmed

Chromosomal assignment of two ADAM genes, TACE (ADAM17) and MLTNB (ADAM19), to human chromosomes 2 and 5, respectively, and of Mltnb to mouse chromosome 11.

ADAM19 ADAM17

4.88e-05314129806848
Pubmed

IRS1 promotes thyroid cancer metastasis through EMT and PI3K/AKT pathways.

IRS1 AKT1

4.88e-053141238172081
Pubmed

Accelerated atherosclerosis in Apoe-/- mice heterozygous for the insulin receptor and the insulin receptor substrate-1.

IRS1 APOE

4.88e-053141222199371
Pubmed

An ITIM-like motif within the CCK2 receptor sequence required for interaction with SHP-2 and the activation of the AKT pathway.

PTPN11 AKT1

4.88e-053141216963136
Pubmed

Remote ischemic postconditioning protects against renal ischemia/reperfusion injury by activation of T-LAK-cell-originated protein kinase (TOPK)/PTEN/Akt signaling pathway mediated anti-oxidation and anti-inflammation.

PBK AKT1

4.88e-053141227355132
Pubmed

GSNOR modulates hyperhomocysteinemia-induced T cell activation and atherosclerosis by switching Akt S-nitrosylation to phosphorylation.

APOE AKT1

4.88e-053141229860106
GeneFamilySulfatases

STS ARSD ARSF

1.02e-0418933410
GeneFamilyParkinson disease associated genes|ATPase orphan transporters

ATP13A1 ATP13A3

2.59e-0459321213
GeneFamilyProteases, serine

TMPRSS15 PRSS8 PRSS22 PRSS45P

3.10e-0463934738
GeneFamilyFibulins

FBLN2 HMCN2

7.18e-048932556
GeneFamilyC2-set domain containing|Immunoglobulin like domain containing|Scavenger receptors

NPHS1 MCAM VCAM1

1.13e-0340933592
GeneFamilyUPF1 like RNA helicases

ZNFX1 AQR

1.40e-03119321169
GeneFamilyFibronectin type III domain containing

BOC NPHS1 ITGB4 ROBO2 ROS1

1.42e-03160935555
GeneFamilyImmunoglobulin like domain containing

BOC NPHS1 MCAM HMCN2 VCAM1

3.20e-03193935594
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

NET1 IRS1 DOK4 AKT1 PHLPP2

4.23e-03206935682
GeneFamilyAminoacyl tRNA synthetases, Class II

NARS2 PARS2

4.23e-0319932132
GeneFamilyC2-set domain containing|Immunoglobulin like domain containing|Scavenger receptors

STAB2 STAB1

8.45e-03279321253
GeneFamilyADAM metallopeptidase domain containing|CD molecules

ADAM19 ADAM17

8.45e-032793247
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

BOC HMCN2 ROBO2 VCAM1

9.58e-03161934593
GeneFamilyRNA polymerase subunits

POLR2B POLR3B

9.71e-0329932726
GeneFamilyAdenosine receptors|V-set domain containing

NPHS1 MCAM ACAN CD79B

9.99e-03163934590
CoexpressionGSE14308_TH17_VS_NAIVE_CD4_TCELL_UP

ACTR10 MCAM QRICH1 MND1 ARMCX4 STAB1 DDIAS CD79B

8.66e-062001338M3382
CoexpressionNAKAYA_PLASMACYTOID_DENDRITIC_CELL_FLUMIST_AGE_18_50YO_7DY_DN

ENGASE TNFRSF25 STAB2 ADAM19 REPS1 HK3 PRSS22 RCC1 APOE ITGB4 MEGF6 ACAN USP32 FZD10 CD79B SERPIND1

1.55e-0590913316M41018
CoexpressionTABULA_MURIS_SENIS_BROWN_ADIPOSE_TISSUE_B_CELL_AGEING

ACTR10 CCDC80 APOE SIPA1 PFN1 TMEM160 EXOSC6 VCAM1 AQR

3.12e-053111339MM3674
CoexpressionZHANG_ADIPOGENESIS_BY_BMP7

IRS1 MAP3K5 AKT1

4.46e-05141333MM1324
CoexpressionZHANG_ADIPOGENESIS_BY_BMP7

IRS1 MAP3K5 AKT1

4.46e-05141333M2511
CoexpressionTABULA_MURIS_SENIS_MESENTERIC_ADIPOSE_TISSUE_MACROPHAGE_AGEING

CCDC80 APOE PFN1 TMEM160 UAP1L1

4.60e-05771335MM3781
ToppCellfacs-Lung-18m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MCAM LAMA3 CCDC80 ARMCX4 ITGB4 STAB1 FBLN2 ATP13A3 UBE2QL1 VCAM1 FOXC2

7.03e-121801321167c5068b660cd5e727a665cefe3bd5f8ae887221
ToppCellfacs-Lung-18m-Endothelial-arterial_endothelial|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MCAM LAMA3 CCDC80 ITGB4 STAB1 FBLN2 ATP13A3 UBE2QL1 VCAM1 FOXC2

1.86e-1018213210ebc812ed3f25839ea25f76b952c463d79a8325b1
ToppCellfacs-Lung-18m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MCAM LAMA3 CCDC80 ITGB4 STAB1 FBLN2 ATP13A3 UBE2QL1 VCAM1 FOXC2

1.86e-101821321047ff6b4002a4167412c79210651316d1342503f9
ToppCellfacs-Lung-Endomucin_-18m-Endothelial-Artery_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

USP28 CCDC80 ARMCX4 ITGB4 ABCB4 STAB1 FBLN2 ATP13A3 VCAM1

3.75e-0918113294ea02344e1996f264dd5e14f3b19c8782ce41699
ToppCellE16.5-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

STAB2 ANGPT2 PPFIBP1 ARMCX4 SIPA1 STAB1 FBLN2 FOXC2

3.79e-081671328fcd583b1efd0ac883379982ea8e6c54f2c0be268
ToppCellE16.5-Endothelial-Endothelial_lymphatic-Lymphatic_EC|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

STAB2 ANGPT2 PPFIBP1 ARMCX4 SIPA1 STAB1 FBLN2 FOXC2

3.79e-081671328f6bc63138b7239211fa5f27a8dc799b6e022c0f8
ToppCellE16.5-Endothelial-Endothelial_lymphatic|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

STAB2 ANGPT2 PPFIBP1 ARMCX4 SIPA1 STAB1 FBLN2 FOXC2

3.79e-081671328b93103a868fba63a8910bffb690a6242b9252833
ToppCellE16.5-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

STAB2 ANGPT2 PPFIBP1 ARMCX4 SIPA1 STAB1 FBLN2 FOXC2

3.79e-08167132826cd8ee5e826e71eaf58d10a906543a6932fb3f9
ToppCell367C-Endothelial_cells-Endothelial-F_(Lymphatics)-|367C / Donor, Lineage, Cell class and subclass (all cells)

STAB2 ANGPT2 PPFIBP1 CRTAC1 ITGB4 JUP FZD10 FOXC2

7.07e-081811328b244ecaa442bbef51289d8ec574ef08fa9e96318
ToppCell367C-Endothelial_cells-Endothelial-F_(Lymphatics)|367C / Donor, Lineage, Cell class and subclass (all cells)

STAB2 ANGPT2 PPFIBP1 CRTAC1 ITGB4 JUP FZD10 FOXC2

7.07e-081811328dd79de8098edb385a0f85d0e9621503cdf76ec43
ToppCelldroplet-Lung-21m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MCAM LAMA3 CCDC80 ITGB4 FBLN2 ZFTA ATP13A3 VCAM1

7.38e-081821328c7f2d24697affa530b748ab32b1d40bdc1bdc20a
ToppCelldroplet-Lung-21m-Endothelial-arterial_endothelial|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MCAM LAMA3 CCDC80 ITGB4 FBLN2 ZFTA ATP13A3 VCAM1

7.38e-081821328d95635b74e8cd8bc00bfe40340806b59fb9bee43
ToppCellfacs-Lung-nan-3m-Endothelial-Artery_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MCAM LAMA3 CCDC80 ITGB4 FBLN2 ATP13A3 VCAM1 FOXC2

7.70e-08183132812e876d6205af8aad74265c668b5e95b9e7487f3
ToppCelldroplet-Lung-18m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MCAM CCDC80 ARMCX4 ITGB4 FBLN2 ATP13A3 VCAM1 FOXC2

8.73e-0818613289c7924875f70420720149287c500b4dfa8d24673
ToppCelldroplet-Lung-1m-Endothelial-arterial_endothelial|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ARHGEF28 LAMA3 CCDC80 ITGB4 FBLN2 MEGF6 VCAM1 FOXC2

8.73e-081861328ffbc78058be8f0dc2e0335cc4c3195a636d17721
ToppCelldroplet-Lung-1m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ARHGEF28 LAMA3 CCDC80 ITGB4 FBLN2 MEGF6 VCAM1 FOXC2

8.73e-081861328ed924852cd7132c8f6703522037dc22bd2c83193
ToppCellfacs-Lung-ENDOMUCIN-18m-Endothelial-Artery_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MCAM LAMA3 CCDC80 ITGB4 FBLN2 ATP13A3 VCAM1 FOXC2

8.73e-0818613285302399825f213d105ac70b91366a4513b732838
ToppCellPND10-Endothelial-Endothelial_lymphatic|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

STAB2 ARHGEF28 ANGPT2 PPFIBP1 ITGB4 STAB1 FOXC2

6.05e-071641327f13b8d9b7f42193f333d9a77571a1dde6bbb48d8
ToppCellPND10-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

STAB2 ARHGEF28 ANGPT2 PPFIBP1 ITGB4 STAB1 FOXC2

6.05e-0716413274cfc9f92e49f86d3639e018b35b6a60dc62f494a
ToppCellPND10-Endothelial-Endothelial_lymphatic-Lymphatic_EC|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

STAB2 ARHGEF28 ANGPT2 PPFIBP1 ITGB4 STAB1 FOXC2

6.05e-0716413277a8e5ef52a8fd2877d59ef0696af8a7af90bbed6
ToppCellPND10-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

STAB2 ARHGEF28 ANGPT2 PPFIBP1 ITGB4 STAB1 FOXC2

6.05e-0716413275e5bd81414ea2d64f73cdef19a0a78c17bec8c18
ToppCellkidney_cells-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ANGPT2 PPFIBP1 CRTAC1 ITGB4 STAB1 FBLN2 STS

1.01e-06177132766ffa279147961080c104242a08b176e301d80e3
ToppCellkidney_cells-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ANGPT2 PPFIBP1 CRTAC1 ITGB4 STAB1 FBLN2 STS

1.01e-061771327227d4f423b00be2e0c5797e2c5275d342e69a0f4
ToppCellkidney_cells-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ANGPT2 PPFIBP1 CRTAC1 ITGB4 STAB1 FBLN2 STS

1.01e-0617713270cbf54608d2ba0a0500af142f2029fe5e118c3c2
ToppCellfacs-Lung-18m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LAMA3 CCDC80 CRTAC1 ITGB4 ABCB4 FBLN2 VCAM1

1.01e-061771327d68132e145bd413404fdbe215b5dbe520e756e50
ToppCelldroplet-Kidney-nan-21m-Epithelial-Pecam____kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NPHS1 ANGPT2 DNAH10 CCDC80 ROBO2 UBE2QL1 FOXC2

1.26e-061831327f55081068213cc1cdb2acad58ff10f6b48b44c72
ToppCelldroplet-Lung-LUNG-1m-Endothelial-Artery_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGEF28 LAMA3 CCDC80 ITGB4 FBLN2 MEGF6 FOXC2

1.41e-0618613271e67bfb248366d7395efdd2d5e70a97bdb2e68af
ToppCelldroplet-Lung-18m-Endothelial-arterial_endothelial|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MCAM CCDC80 ARMCX4 ITGB4 FBLN2 VCAM1 FOXC2

1.46e-06187132712129e02638c20d9b7c1c6e512d48bfd966e1029
ToppCelldroplet-Lung-18m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MCAM CCDC80 ARMCX4 ITGB4 FBLN2 VCAM1 FOXC2

1.46e-06187132783930ef55191eff9006113feaeabb3c2fa21fd05
ToppCellE12.5-Mesenchymal-mesenchymal_fibroblast-tracheal_fibroblast|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

BOC NET1 FBLN2 IGFBP2 ACAN ROBO2 FOXC2

1.51e-0618813279b95730ddd13eb4624321bab3ab4989414977ca3
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_2_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

BOC ADAMTS19 TTC28 CCDC80 MAP3K5 FBLN2 VCAM1

1.62e-0619013270fea33f2dc1efa23aaa2da1c318482a52a313ff1
ToppCellwk_20-22-Endothelial-Lymph_endothelial|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

STAB2 ANGPT2 PPFIBP1 CRTAC1 JUP FZD10 FOXC2

1.68e-061911327631f95fd80dd3678b5b2ef201abf7fe646049af6
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MCAM CCDC80 ARMCX4 ITGB4 FBLN2 MEGF6 ATP13A3

1.74e-061921327285a9d332a1e07b94f222d4b518dd56928b9e075
ToppCell(6)_Endothelial_cells-(6)_Endothelial-F_(Lymphatics)|(6)_Endothelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)

STAB2 ADAM19 PPFIBP1 CCDC80 CRTAC1 JUP FOXC2

1.86e-0619413279441202d6fa2ffbef9277d48ae9bc98876c26ec5
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-Mono-Mono_hypoxia|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

LST1 ADAM19 HK3 PFN1 STAB1 ATP13A3 UAP1L1

1.99e-061961327a44a648bf209ce037bfc7b3adfcb220aab60728c
ToppCellbackground-Endothelial_cells|background / Sample and Cell Type and Tumor Cluster (all cells)

STAB2 ANGPT2 PPFIBP1 MCAM DENND4C STAB1 ROBO2

1.99e-061961327e6fb0bfab1779ec64a8c35d01519eaafbf62e977
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NPHS1 ADAMTS19 CCDC80 IGFBP2 DCBLD2 VCAM1 FOXC2

1.99e-061961327545d2e4469924d333e3f655f559c899fa1260196
ToppCell390C-Endothelial_cells-Endothelial-F_(Lymphatics)-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

STAB2 ADAM19 PPFIBP1 CCDC80 JUP MEGF6 FOXC2

2.06e-061971327c84e988c2ad06087aafda9e3b68e9e72fd0e75f1
ToppCell390C-Endothelial_cells-Endothelial-F_(Lymphatics)|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

STAB2 ADAM19 PPFIBP1 CCDC80 JUP MEGF6 FOXC2

2.06e-0619713276195f945b3fd6da07907619267d49e96d1044f8f
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial-Vein|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

NET1 CRTAC1 ITGB4 ABCB4 STAB1 FBLN2 VCAM1

2.28e-0620013277eb366b2c5394af7c77650bde6261e7dac67154e
ToppCellNS-control|NS / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ARHGEF28 NET1 CCDC80 ITGB4 JUP IGFBP2 ARSD

2.28e-062001327ecbe89ff95d046155b984c8c150e0b9e7278f839
ToppCellmetastatic_Brain-B_lymphocytes-Undetermined|metastatic_Brain / Location, Cell class and cell subclass

GTPBP1 NFATC2 CD79B UBE2QL1 BFSP2 PHLPP2

9.26e-0616313264eac7fd8acdb7f09ce739335f22a879f9b8febfb
ToppCellPND03-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

STAB2 ANGPT2 PPFIBP1 STAB1 FZD10 FOXC2

9.93e-061651326347b59aa625a8a960828b8620824d8ac48990e07
ToppCellPND03-Endothelial-Endothelial_lymphatic|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

STAB2 ANGPT2 PPFIBP1 STAB1 FZD10 FOXC2

9.93e-0616513261890f9c33b0c5b381d57f97042da2610a093a6de
ToppCellPND03-Endothelial-Endothelial_lymphatic-Lymphatic_EC|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

STAB2 ANGPT2 PPFIBP1 STAB1 FZD10 FOXC2

9.93e-061651326507c89ece0a336b8e9c65b79889a714e17ddca27
ToppCellPND03-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

STAB2 ANGPT2 PPFIBP1 STAB1 FZD10 FOXC2

9.93e-06165132639a25be081a5d59c7cf107a997d352793d5025fb
ToppCellPND28-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

STAB2 CCDC80 ITGB4 FBLN2 MEGF6 VCAM1

1.06e-051671326f01b96173deda0239fa482989873cf308e49d48c
ToppCellPND28-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

STAB2 CCDC80 ITGB4 FBLN2 MEGF6 VCAM1

1.06e-0516713265fc85a05124cd2324e1b8ff940193880f83cd8af
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ATP6V1A ARHGEF28 LAMA3 CNTNAP5 PLCG2 UBE2QL1

1.14e-0516913264b3a7b4a497178799b6b2f0b744f5fb752cee31a
ToppCelldroplet-Spleen-SPLEEN-1m-Myeloid-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LST1 STAB2 GPR82 JUP FZD10 VCAM1

1.14e-0516913263f8aa6d2f9aa060ae1a0ea3eb47e794099fc2c2c
ToppCelldroplet-Spleen-SPLEEN-1m-Myeloid|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LST1 STAB2 GPR82 JUP FZD10 VCAM1

1.14e-05169132626de495c7562e0740689d0f78e803698e3e793db
ToppCellPND01-Endothelial-Endothelial_lymphatic-Lymphatic_EC|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

STAB2 ANGPT2 PPFIBP1 STAB1 UBE2QL1 FOXC2

1.18e-05170132635e3945d8a540a3e2cec1b559316265aaad023d1
ToppCellPND01-Endothelial-Endothelial_lymphatic|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

STAB2 ANGPT2 PPFIBP1 STAB1 UBE2QL1 FOXC2

1.18e-0517013260ea625abaa25bab93b70b7000e8f90d5c0f9a0fb
ToppCellPND01-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

STAB2 ANGPT2 PPFIBP1 STAB1 UBE2QL1 FOXC2

1.18e-0517013260b5ddc7d452db0a389927a367914f7d257703f7e
ToppCelldroplet-Spleen-SPLEEN-1m-Myeloid-macrophage|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LST1 STAB2 GPR82 JUP FZD10 VCAM1

1.18e-051701326670027daec5a10dfa12246f1497b58db21d32a22
ToppCellfacs-Lung-Endomucin-24m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMPRSS15 STAB2 PPFIBP1 STAB1 ZFTA UBE2QL1

1.43e-051761326057d2759fdc67176c25802b57a78064d8cc93205
ToppCellfacs-Lung-Endomucin-24m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMPRSS15 STAB2 PPFIBP1 STAB1 ZFTA UBE2QL1

1.43e-051761326b81e5d23b31cefc8d374ef403e21acc390c14a80
ToppCellfacs-Bladder-nan-24m-Epithelial|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACAA1 PRSS22 PFN1 JUP IGFBP2 TMEM160

1.58e-051791326fc9f44fb81da0d381a5141a95a005e66a0be28cc
ToppCellfacs-Bladder-nan-24m|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACAA1 PRSS22 PFN1 JUP IGFBP2 TMEM160

1.58e-0517913269152d92bb96e65d43de54e933494f0d08ae02c4f
ToppCell5'-GW_trimst-2-LymphNode-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NET1 LAMA3 APOE TNMD ACAN FOXC2

1.68e-05181132659527ad218e49386b04cabb97d53d2ed55a35961
ToppCellPericytes-SSc-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

MCAM ADCY1 HMCN2 ACAN FZD10 FOXC2

1.68e-05181132635c470988a93381eefa300831aabb813fa1b90bd
ToppCelldroplet-Lung-1m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TTC28 LAMA3 ITGB4 ERLIN2 VCAM1 FOXC2

1.68e-051811326136b0c60680068838d184d32aa99d7bea8718dbc
ToppCellfacs-Lung-24m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

STAB2 ANGPT2 PPFIBP1 STAB1 ZFTA UBE2QL1

1.73e-0518213262cc434e46985c66fc36de05344a67aa96d90abc9
ToppCellfacs-Lung-24m-Endothelial-lymphatic_endothelial|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

STAB2 ANGPT2 PPFIBP1 STAB1 ZFTA UBE2QL1

1.73e-0518213260cde2775bdaaa2172499925bd59b0ac2d545eb27
ToppCellfacs-Lung-24m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

STAB2 ANGPT2 PPFIBP1 STAB1 ZFTA UBE2QL1

1.73e-0518213263e7457b2a70b45735fb75d6617b7f34cef28758e
ToppCellBasal|World / shred by cell class for mouse tongue

LAMA3 APOE ITGB4 IGFBP2 MEGF6 WDR6

1.79e-051831326c6729a207526ff4aa48176207b9353176f631fea
ToppCellP03-Endothelial-lymphatic_endothelial_cell-endothelial_cell_of_lymphatic_vessel|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

STAB2 ANGPT2 PPFIBP1 STAB1 UBE2QL1 FOXC2

1.79e-05183132689727b4f65949ed2dce9d2e0228c79fe4280230c
ToppCellfacs-Bladder-nan-24m-Epithelial-nan|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACAA1 PRSS22 PFN1 JUP IGFBP2 TMEM160

1.79e-051831326268fc48ffd88e19c9dcd1af32b635256fc915742
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2-CAP2_prolif|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

REPS1 DCBLD1 DGKQ IRS1 ZFTA PHLPP2

1.79e-0518313263ef9ac1ae13b6172f9121ab1c129ecaa0fef460f
ToppCellP03-Endothelial-lymphatic_endothelial_cell|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

STAB2 ANGPT2 PPFIBP1 STAB1 UBE2QL1 FOXC2

1.79e-051831326113e6d8d4bb271be984af06cd6c22b180425dcfc
ToppCelldroplet-Lung-21m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MCAM LAMA3 ITGB4 FBLN2 ZFTA ATP13A3

1.84e-051841326087666ba949b129c53d7ace40f9e543e3875a7de
ToppCelldroplet-Lung-nan-3m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPFIBP1 CREB3L4 STAB1 FBLN2 MEGF6 FOXC2

1.90e-0518513266a85399cfdb9b89683c874e7f046957f9a601dc2
ToppCelldroplet-Lung-nan-3m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPFIBP1 CREB3L4 STAB1 FBLN2 MEGF6 FOXC2

1.90e-05185132664791056cdbb739136dbef08f4b16e2b5427faad
ToppCelldroplet-Lung-nan-3m-Endothelial-Artery_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MCAM CCDC80 STAB1 FBLN2 VCAM1 FOXC2

1.90e-051851326eeb6f55a6f79adf80247baa2c4b0df44553557ad
ToppCell3'-Child09-12-SmallIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

STAB2 ANGPT2 PPFIBP1 LHFPL1 UBE2QL1 FOXC2

1.90e-0518513269de1db2ce9e44956b1214daf6e1e161334679c88
ToppCell3'-Child09-12-SmallIntestine-Endothelial-lymphatic_endothelial|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

STAB2 ANGPT2 PPFIBP1 LHFPL1 UBE2QL1 FOXC2

1.90e-05185132618f5d9438c76e37988a7d17aa2a080af6bedbfc4
ToppCellEndoth-Lymph|World / shred by cell class for parenchyma

STAB2 ADAM19 ANGPT2 PPFIBP1 STAB1 FOXC2

1.90e-05185132697a6c4cd00684d4085d36ef32f7dbb99563ed357
ToppCellfacs-Lung-EPCAM-24m-Hematologic-Proliferating_Immune|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACAA1 L3MBTL2 PRSS22 PBK PARS2 IGFBP2

1.96e-0518613269ce3bd121869215a4e6114a310f9d2fb5adaef61
ToppCelldroplet-Lung-LUNG-30m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STAB2 ANGPT2 PPFIBP1 ARMCX4 STAB1 FOXC2

1.96e-0518613260de87109da9324c597fadf2eb782f0f158afe832
ToppCellfacs-Lung-EPCAM-24m-Hematologic-leukocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACAA1 L3MBTL2 PRSS22 PBK PARS2 IGFBP2

1.96e-051861326a7fd35eabcfb534019dfe5a8a600bf2ec47c1ac2
ToppCelldroplet-Lung-LUNG-30m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STAB2 ANGPT2 PPFIBP1 ARMCX4 STAB1 FOXC2

1.96e-051861326f23f21781a758541f59c06efa7739d26a03fb478
ToppCellfacs-Lung-EPCAM-24m-Hematologic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACAA1 L3MBTL2 PRSS22 PBK PARS2 IGFBP2

1.96e-05186132618c40203463d4dd8558c04977d52e400a8268f90
ToppCell10x3'2.3-week_12-13-Mesenchymal_adipo|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

CCDC80 CRTAC1 SEMA6D ACAN VCAM1 FOXC2

2.02e-051871326f1d0fc625e0e7881b3f290742fd7148d995eb71e
ToppCell5'-GW_trimst-2-LymphNode-Mesenchymal-Pericytes-angiogenic_pericyte|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ANGPT2 LAMA3 APOE TNMD ACAN DCBLD2

2.02e-051871326b8f88599e22b9b345c7ec3bbecd87a8b2a033f9f
ToppCell10x3'2.3-week_12-13-Mesenchymal_adipo-stroma|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

CCDC80 CRTAC1 SEMA6D ACAN VCAM1 FOXC2

2.02e-05187132602e7246ef5ad41773d14426254e139b156d45c1d
ToppCell10x3'2.3-week_12-13-Mesenchymal_adipo-stroma-adipo-CAR|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

CCDC80 CRTAC1 SEMA6D ACAN VCAM1 FOXC2

2.02e-05187132608c73d125e0638c9e9878165bba2442c266c8a48
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ANGPT2 NET1 APOE TNMD ACAN FOXC2

2.08e-051881326c2321a3a1d9603f8b4b4fc09707eb32ec1e04f3f
ToppCellEC-Sinusoidal_ECs|World / Lineage and Cell class

STAB2 MCAM DCBLD1 STAB1 IGFBP2 DOK4

2.14e-0518913269a0956c8a7069ba3bd0fa56d052d6e514453e578
ToppCellnormal_Lung-Endothelial_cells-Lymphatic_ECs|normal_Lung / Location, Cell class and cell subclass

STAB2 ANGPT2 PPFIBP1 ITGB4 FZD10 FOXC2

2.21e-0519013262185db6007404a2b22325f91460dd17635be9bba
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MCAM ARMCX4 ITGB4 FBLN2 MEGF6 ATP13A3

2.21e-051901326d87b9e9ca863270a9c7f61674271a6440c97d1f4
ToppCellwk_20-22-Endothelial-Lymph_endothelial-Intermediate_lymphatic_endo|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

STAB2 PPFIBP1 CRTAC1 ITGB4 FZD10 FOXC2

2.21e-051901326103e78c2233c3ee0c215a9dafe70705477e9ee5e
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ATP6V1A IRS1 APOE CNTNAP5 PLCG2 UBE2QL1

2.21e-051901326bb3b396d78887d5d6f93a05c8ed4d703591bf33f
ToppCelldroplet-Lung-1m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ARHGEF28 CCDC80 ITGB4 FBLN2 MEGF6 FOXC2

2.21e-0519013263b9abc25b17e7295356ded57ff2ca519fa9f2686
ToppCell368C-Lymphocytic-NK_cells-NK_cell_D3|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

QRICH1 EPM2AIP1 PTPN11 FBLN2 IGFBP2 TNPO3

2.27e-051911326d7920f4a602b50d0ef064eb47001e71939695ed2
ToppCelldroplet-Lung-30m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

STAB2 ANGPT2 PPFIBP1 STAB1 FBLN2 FOXC2

2.27e-05191132651cff0594ac7ad8c065c8ea2301f8c149bd062b4
ToppCelldroplet-Lung-30m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

STAB2 ANGPT2 PPFIBP1 STAB1 FBLN2 FOXC2

2.27e-051911326a55b6f0a7ec1a8852ffca593cfdccd7edea09b7b
ToppCelldroplet-Lung-30m-Endothelial-lymphatic_endothelial|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

STAB2 ANGPT2 PPFIBP1 STAB1 FBLN2 FOXC2

2.27e-05191132638681a1b182d6af5cce85db5431b6eba4b20ad96
ToppCell368C-Endothelial_cells-Endothelial-F_(Lymphatics)|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

PPFIBP1 CCDC80 CRTAC1 JUP FZD10 FOXC2

2.34e-051921326b016e229300c183e14c0e2bba494bf49c7899112
ToppCell368C-Endothelial_cells-Endothelial-F_(Lymphatics)-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

PPFIBP1 CCDC80 CRTAC1 JUP FZD10 FOXC2

2.34e-051921326ac96831492c62ad9e1f7d0b764fbdf7d8a189ad9
ToppCellfacs-Bladder-nan-18m-Epithelial-bladder_urothelial_cell|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACAA1 NET1 PRSS22 ITGB4 JUP IGFBP2

2.34e-05192132618546b4d5e39aafa97186104d47cfda02eb5f4b5
DrugMethylhydantoin-5-(D) [55147-68-7]; Up 200; 35uM; PC3; HT_HG-U133A

CDK20 TNFRSF25 CRTAC1 APOE ARSD SEMA6D MEGF6 DOK4 PHLPP2

2.50e-0619613493994_UP
Diseasemembranous glomerulonephritis (biomarker_via_orthology)

NPHS1 APOE MAP3K5

2.87e-05141293DOID:10976 (biomarker_via_orthology)
Diseaseapolipoprotein A 1 measurement

ARHGEF28 REPS1 DNAH10 HMBS DGKQ CRTAC1 APOE GTPBP1 STAB1 PTPN11 DOK4 TMEM160 AKT1

9.14e-0584812913EFO_0004614
DiseaseFamilial intrahepatic cholestasis of pregnancy

ABCB4 VCAM1

1.13e-0441292C3489728
Diseaseautosomal recessive congenital ichthyosis 4B (implicated_via_orthology)

PRSS8 ABCA12

1.13e-0441292DOID:0060713 (implicated_via_orthology)
DiseaseChronic Liver Failure

ABCB4 NOS1

1.13e-0441292C2936476
DiseaseHerlitz Disease

LAMA3 ITGB4

1.13e-0441292C0079683
DiseaseEnd Stage Liver Disease

ABCB4 NOS1

1.13e-0441292C0745744
DiseaseEpidermolysis Bullosa Progressiva

LAMA3 ITGB4

1.13e-0441292C0079297
DiseaseAdult junctional epidermolysis bullosa (disorder)

LAMA3 ITGB4

1.88e-0451292C0268374
DiseaseEPIDERMOLYSIS BULLOSA, JUNCTIONAL, LOCALISATA VARIANT (disorder)

LAMA3 ITGB4

1.88e-0451292C2608084
Diseasejunctional epidermolysis bullosa non-Herlitz type (implicated_via_orthology)

LAMA3 ITGB4

1.88e-0451292DOID:0060738 (implicated_via_orthology)
DiseaseCardiomyopathies

MAP3K5 JUP PTPN11 AKT1 TAFAZZIN

2.73e-041301295C0878544
Diseasesuccinate measurement

ADAMTS19 SEMA6D

2.81e-0461292EFO_0011002
DiseaseJunctional Epidermolysis Bullosa

LAMA3 ITGB4

2.81e-0461292C0079301
DiseaseLiver diseases

HK3 ABCB4 JUP CD79B

2.85e-04721294C0023895
DiseaseLiver Dysfunction

HK3 ABCB4 JUP CD79B

2.85e-04721294C0086565
Diseasejunctional epidermolysis bullosa (is_implicated_in)

LAMA3 ITGB4

3.93e-0471292DOID:3209 (is_implicated_in)
DiseaseCholestasis of pregnancy

ABCB4 VCAM1

5.22e-0481292C0268318
Diseasesystemic scleroderma, rheumatoid arthritis, myositis, systemic lupus erythematosus

DGKQ PTPN11 TNPO3

6.16e-04381293EFO_0000685, EFO_0000717, EFO_0000783, MONDO_0007915
Diseasereticulocyte count

ARHGEF28 DNAH10 LAMA3 POR IRS1 MND1 APOE SIPA1 NARS2 ABCB4 PTPN11 USP32 PLCG2

6.80e-04104512913EFO_0007986
Diseasemembranoproliferative glomerulonephritis (implicated_via_orthology)

ANGPT2 PFN1

8.34e-04101292DOID:2920 (implicated_via_orthology)
Diseasecoffee consumption measurement, tea consumption measurement

POR HORMAD1 TMEM160

9.48e-04441293EFO_0006781, EFO_0010091
DiseaseMultiple Sclerosis

MCAM APOE VCAM1

1.01e-03451293C0026769
Diseasediabetic retinopathy (biomarker_via_orthology)

ANGPT2 AKT1 NOS1

1.01e-03451293DOID:8947 (biomarker_via_orthology)
DiseaseMultiple Sclerosis, Acute Fulminating

MCAM APOE VCAM1

1.01e-03451293C0751324
DiseasePancreatic Ductal Adenocarcinoma

ADAM19 ABCA12

1.02e-03111292C1335302
Diseasepancreatic cancer (is_marker_for)

APOE PFN1 AKT1 VCAM1

1.03e-031011294DOID:1793 (is_marker_for)
Diseasemultiple sclerosis symptom measurement

STAB2 DNAH10 USP32

1.08e-03461293EFO_0803536
Diseaseretinopathy of prematurity (biomarker_via_orthology)

ANGPT2 NOS1

1.22e-03121292DOID:13025 (biomarker_via_orthology)
DiseaseAlzheimer disease, dementia, family history of Alzheimer’s disease

DCBLD1 APOE POLR3B

1.22e-03481293EFO_0009268, MONDO_0001627, MONDO_0004975
DiseaseProstatic Neoplasms

TRPM4 PRSS8 STAB2 USP28 IRS1 CREB3L4 JUP ROBO2 AKT1

1.59e-036161299C0033578
DiseaseMalignant neoplasm of prostate

TRPM4 PRSS8 STAB2 USP28 IRS1 CREB3L4 JUP ROBO2 AKT1

1.59e-036161299C0376358
Disease3-hydroxyanthranilic acid measurement

TG PCNX2

1.92e-03151292EFO_0010447
Diseaseimpotence (implicated_via_orthology)

AKT1 NOS1

1.92e-03151292DOID:1875 (implicated_via_orthology)
DiseaseAlzheimer's disease (biomarker_via_orthology)

IRS1 APOE ADAM17

2.11e-03581293DOID:10652 (biomarker_via_orthology)
DiseaseObesity

IRS1 APOE STS IGFBP2 AKT1

2.11e-032051295C0028754
Diseaseidiopathic scoliosis (implicated_via_orthology)

DNAH10 PTPN11

2.19e-03161292DOID:0060250 (implicated_via_orthology)
Diseasereticulocyte measurement

ARHGEF28 DNAH10 ACTR10 IRS1 MND1 APOE SIPA1 NARS2 MAP3K5 ABCB4 USP32 PLCG2

2.29e-03105312912EFO_0010700
DiseaseInsulin Resistance

IRS1 STS IGFBP2

2.33e-03601293C0021655
DiseaseInsulin Sensitivity

IRS1 STS IGFBP2

2.33e-03601293C0920563
DiseaseLipidemias

IRS1 APOE

2.47e-03171292C1706412
DiseaseHyperlipidemia

IRS1 APOE

2.47e-03171292C0020473
DiseaseAlzheimer's disease (is_implicated_in)

IRS1 APOE ADAM17 NOS1

2.74e-031321294DOID:10652 (is_implicated_in)
Diseaseportal hypertension (implicated_via_orthology)

ANGPT2 NOS1

3.09e-03191292DOID:10762 (implicated_via_orthology)
Diseasep-tau:beta-amyloid 1-42 ratio measurement

TTC28 APOE

3.09e-03191292EFO_0007709
Diseaselimited scleroderma

DGKQ TNPO3

3.09e-03191292EFO_1001017
Diseaseleukemia (implicated_via_orthology)

PTPN11 DOT1L

3.09e-03191292DOID:1240 (implicated_via_orthology)
DiseaseParkinson's disease (is_marker_for)

APOE AKT1 NOS1

3.19e-03671293DOID:14330 (is_marker_for)
Diseasehypertension (biomarker_via_orthology)

APOE STS IGFBP2 NOS1 VCAM1

3.28e-032271295DOID:10763 (biomarker_via_orthology)
Diseaseend stage renal disease (implicated_via_orthology)

IRS1 NOS1

3.42e-03201292DOID:783 (implicated_via_orthology)
Diseaseactivities of daily living score measurement

FZD10 NOS1

3.77e-03211292EFO_0008451
Diseaseceramide measurement

ATP6V1A ADAM19 APOE CREB3L4 PLCG2

3.80e-032351295EFO_0010222
Diseaseseminoma (is_marker_for)

HMBS JUP

4.14e-03221292DOID:4440 (is_marker_for)
Diseaseimpotence (biomarker_via_orthology)

MCAM NOS1

4.14e-03221292DOID:1875 (biomarker_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
DRLCFVMEYANGGEL

AKT1

221

P31749
MVDDLGIGDLGCYGN

ARSF

36

P54793
GIGDLGCYGNDTMRT

ARSF

41

P54793
IMADDLGTGDLGCYG

ARSD

46

P51689
MDQYCILGRIGEGAH

CDK20

1

Q8IZL9
EEEGLRLVCGEMAYQ

ATG16L2

96

Q8NAA4
MEDVCGRLVQYRGEV

APOE

126

P02649
DQCNDVGLMAYLGTI

COPS6

281

Q7L5N1
VGMGQKDCYVGDEAQ

ACTBL2

46

Q562R1
ELDRYLQSGGGMCLS

ADAM19

391

Q9H013
LQNVDYFVGMCGDGA

ATP13A3

871

Q9H7F0
RALDNGMGDLNIGCY

ABCA12

1636

Q86UK0
GMGDLNIGCYGISDT

ABCA12

1641

Q86UK0
GYVTLMCGDGTNDVG

ATP13A1

856

Q9HD20
CMYVCVDREADGGGD

GJA10

511

Q969M2
MDEGCGETIYVIGQG

GTPBP1

86

O00178
KVTDISGGCGAMYEI

BOLA3

51

Q53S33
SGGCGAMYEIKIESE

BOLA3

56

Q53S33
TEEIKAYCDMEAGGG

ANGPT2

306

O15123
QMSNYCGIGIDAELS

DGKQ

741

P52824
YVRGCEIQGMLDDKG

AQR

591

O60306
LSMNGQAAGYELCGV

DOT1L

711

Q8TEK3
GAVEDLGGCLVEYMA

BFSP2

106

Q13515
EVYQGCGTELRVMGF

CD79B

131

P40259
RSEEVAYMGSCVGAE

ARMCX4

1796

Q5H9R4
LGINSAMVLDCGYRE

ACTR10

131

Q9NZ32
QQSLGMRCPEDEYAG

CCDC80

906

Q76M96
MLTADGDLYTLGCGE

RCC1

186

P18754
MYVGECQGPGVRTDF

RAB3GAP1

176

Q15042
YGLCLMTREARNGEG

QRICH1

526

Q2TAL8
ACNLDVGGIIADYTM

RIMKLA

286

Q8IXN7
KVMDGTSCGYQGLDI

ADAMTS19

741

Q8TE59
DCDILQLEYVGGISM

SERPIND1

341

P05546
QVEVDENAYRCGSGM

NET1

546

Q7Z628
GRLSDMLNGGDEVYA

ARHGEF28

361

Q8N1W1
DSCLVYGGQQMILTG

NFATC2

586

Q13469
DAEYECQVGRSEMGP

NPHS1

106

O60500
GGGECFLLAAMAYDR

OR2T12

106

Q8NG77
EGEESLCYNRQMELG

GPR82

181

Q96P67
RDYIGMAVVDGQLTC

LAMA3

2446

Q16787
FANDECDYGMGLELG

nan

281

A8MVJ9
EGGAHIYVCGDARNM

POR

621

P16435
DGYLMICVDGGPSTD

L3MBTL2

456

Q969R5
GEEYVCPMELGQASG

PPFIBP1

921

Q86W92
DAGVEMYDLVVGCGL

EXOSC6

171

Q5RKV6
DAGRYQCLAENEMGV

HMCN2

4276

Q8NDA2
LEGEEYRMSGECPSA

KRT3

506

P12035
TENMICAGYEEGGID

TMPRSS15

951

P98073
AGQGPITEDMLCAGY

PRSS22

216

Q9GZN4
ITEDMLCAGYLEGER

PRSS22

221

Q9GZN4
PGYAIMADGVSCEDI

FBLN2

706

P98095
GTYCQQREVEAIMEG

PCNX2

1451

A6NKB5
MGEGTCEKRRDAEYG

IGFBP2

126

P18065
GGGECFLLAAMAYDR

OR2T8

106

A6NH00
DDGMVDCERIGTSNY

MND1

56

Q9BWT6
QENGRLFIVMEYCDG

NEK5

71

Q6P3R8
DGLLYIVMGFCEGGD

NEK4

76

P51957
YLNGCGEISVSEMNE

DDIAS

576

Q8IXT1
DYGMDLIEVSGNGCG

PMS2P11

206

Q13670
LEAGAAGGYQCSMRA

FOXC2

321

Q99958
GEGHSLIMVEECGRY

LHFPL1

56

Q86WI0
CLDVIEGALQMRYGD

KBTBD7

291

Q8WVZ9
LLQEYCMETGGKDGT

PLCG2

546

P16885
MIRCQELKYDVGGGE

PTPN11

171

Q06124
GGGECFLLAAMAYDR

OR2T33

106

Q8NG76
ARGEEELSNYICMGG

IRS1

456

P35568
GLIVGTGTNACYMEE

HK3

681

P52790
IVGYLVTCEMAQGGG

ITGB4

1671

P16144
GIMEEDEACGRQYTL

JUP

41

P14923
NDSGVYRCEVMHGIE

ACAN

126

P16112
CGTSGGVMIYFDRIE

ERLIN2

76

O94905
IAENICYGRGNVTMD

ABCB4

486

P21439
EQGGHIYVCGDVTMA

NOS1

1346

P29475
ETGLMEDVGGRGECY

BECN2

381

A8MW95
AGDELTGVCYVGSMD

FZD10

376

Q9ULW2
ISEYVKACDGIGGAM

ERVK-10

506

P87889
ISEYVKACDGIGGAM

ERVK-21

506

P62683
ISEYVKACDGIGGAM

ERVK-24

506

P63145
ISEYVKACDGIGGAM

ERVK-6

506

Q7LDI9
ISEYVKACDGIGGAM

ERVK-7

506

P63130
ISEYVKACDGIGGAM

ERVK-8

506

P62685
ISEYVKACDGIGGAM

ERVK-9

506

P63126
YIELDGNNMGVECLR

ADCY1

881

Q08828
EEDSGTYRCMADNGV

BOC

291

Q9BWV1
GEGDFVYQCMEVLLR

EPM2AIP1

116

Q7L775
RACGALVYDEEIMAG

DENND4C

1496

Q5VZ89
IIDGGSGYLCEMEPV

CRTAC1

476

Q9NQ79
LGMGARRVCYGQEEA

ENGASE

406

Q8NFI3
GCYGTLGMESGVIAD

DCBLD2

291

Q96PD2
GDCEGVIFEGEPMYL

HORMAD1

196

Q86X24
CMYAVGQGALGVEVR

HMBS

211

P08397
VAGDISGNMVDGYRD

DCBLD1

181

Q8N8Z6
TNCGEGMDYRAVGKI

DNAH10

1856

Q8IVF4
VYEAGALERMQGETG

CREB3L4

116

Q8TEY5
FEAGRMCDAGEGLYT

DOK4

196

Q8TEW6
DYGGSMEQLEAVIDG

CNTNAP5

656

Q8WYK1
CLDVIEGALQMRYGD

KBTBD6

291

Q86V97
MLSRNDDICIYGGLG

LST1

1

O00453
GRYECQGLDLDTMIS

MCAM

316

P43121
SEGQVASDMYCLVGR

MAP3K5

381

Q99683
ELGADGRQCYRIEME

MEGF6

316

O75095
EMGCYGLGVTRILAA

PARS2

336

Q7L3T8
MEDSGVYLCEGINQA

VCAM1

571

P19320
GIRNGSYDIGMACGV

ACAA1

136

P09110
QIMELCGATRLGYFG

REPS1

51

Q96D71
LMADGTCQDAAIVGY

PFN1

11

P07737
GMGFERYLQCILGVD

NARS2

446

Q96I59
KDYGMDLIEVSGNGC

PMS2P2

121

O95744
LVMADDLGIGDPGCY

STS

31

P08842
GIQYRQEDMPFTCEG

POLR2B

946

P30876
QLGDGAAMYLGEVCT

SELENOO

151

Q9BVL4
GILYCRAGQGSEEEM

SIPA1

336

Q96FS4
EGGVGHVEMLFRCNY

WDR45B

51

Q5MNZ6
FVQEDMVCAGYVEGG

PRSS8

216

Q16651
ISEYVKACDGIGGAM

ERVK-9

506

P63128
GCSDEGEAMTMLGRY

TBC1D9B

716

Q66K14
SRVDEGEECDPGIMY

ADAM17

481

P78536
GEECDPGIMYLNNDT

ADAM17

486

P78536
NGIEFDPMLDERGYC

TNMD

251

Q9H2S6
LVLGDMICATNYGEN

PRSS45P

166

Q7RTY3
LENGYVLDGGAICME

UBE2QL1

76

A1L167
VGAMVVYLNIGEEGC

PHLPP2

1026

Q6ZVD8
VCRGDGVYQKGMDFI

TAFAZZIN

121

Q16635
MEAGGFLDSLIYGAC

SLC50A1

1

Q9BRV3
MAPDGNGGLYCALED

UAP1L1

221

Q3KQV9
DGYMGDGELCQEINS

STAB1

1486

Q9NY15
GDGLTCYGNIMERLR

STAB2

356

Q8WWQ8
VIIYVGCGERGNEMS

ATP6V1A

271

P38606
TDEGTYMCIAENRVG

ROBO2

286

Q9HCK4
GLNYMVLATECGQGE

ROS1

2271

P08922
RLGEMERDCLIGYGA

POLR3B

1046

Q9NW08
ANDGSLCLAMEYGGE

PBK

106

Q96KB5
NGYRNLDECLEGAMV

USP28

321

Q96RU2
DGDVMLYRALGGCTR

WDR6

676

Q9NNW5
GAVYAALERMGLDGC

TNFRSF25

391

Q93038
NGHIYVIGDCGGAME

ZNFX1

1851

Q9P2E3
ILVDEYGMEEGCRQG

TNPO3

706

Q9Y5L0
YGMEEGCRQGLLDML

TNPO3

711

Q9Y5L0
ESDAACGLGGVYQQM

TTC28

996

Q96AY4
DVMRETYGHLGALGC

ZNF689

56

Q96CS4
MDTCGVGYVALGEAG

GTF3C2

1

Q8WUA4
CAVGLYMGQLELDVE

TMEM160

151

Q9NX00
CGRVTPGMLAEGYEQ

SEMA6D

541

Q8NFY4
AVLMQCHGGYTDGEQ

UBR2

571

Q8IWV8
VDAEGMEVYGTRQLG

TG

141

P01266
LEGQEASQEGLYMCV

ZNF571

96

Q7Z3V5
GMGVDLFGECYRSSE

TRPM4

621

Q8TD43
YMGQHCFIREVLGDG

USP32

41

Q8NFA0
YLMELDGGRRGLVCG

ZFTA

426

C9JLR9