Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
DomainSpectrin_repeat

SPTBN2 EVPL PPL SYNE2 MACF1

3.85e-06291565IPR002017
DomainYTH

YTHDF1 YTHDF2 YTHDF3

5.65e-0651563PF04146
DomainYTH_domain

YTHDF1 YTHDF2 YTHDF3

5.65e-0651563IPR007275
DomainYTH

YTHDF1 YTHDF2 YTHDF3

5.65e-0651563PS50882
DomainSPEC

SPTBN2 EVPL PPL SYNE2 MACF1

6.40e-06321565SM00150
DomainSpectrin/alpha-actinin

SPTBN2 EVPL PPL SYNE2 MACF1

6.40e-06321565IPR018159
DomainPlectin

EVPL PPL MACF1

1.95e-0571563PF00681
DomainPlectin_repeat

EVPL PPL MACF1

1.95e-0571563IPR001101
DomainPLEC

EVPL PPL MACF1

1.95e-0571563SM00250
DomainCNH

TNIK MINK1 MAP4K4

1.94e-04141563SM00036
DomainCNH

TNIK MINK1 MAP4K4

2.42e-04151563PF00780
DomainCNH

TNIK MINK1 MAP4K4

2.42e-04151563PS50219
DomainCNH_dom

TNIK MINK1 MAP4K4

2.42e-04151563IPR001180
DomainC345C

C3 NTN1 PCOLCE

3.57e-04171563SM00643
DomainNTR

C3 NTN1 PCOLCE

5.02e-04191563PF01759
DomainNetrin_module_non-TIMP

C3 NTN1 PCOLCE

5.02e-04191563IPR018933
DomainZnF_Rad18

RAD18 POLK

6.82e-0451562SM00734
DomainZnf_Rad18_put

RAD18 POLK

6.82e-0451562IPR006642
DomainLRR_TYP

LRRC8C ASPN ECM2 LRRC69 LRRIQ1 LRRC53 FLRT2

7.26e-041771567SM00369
DomainLeu-rich_rpt_typical-subtyp

LRRC8C ASPN ECM2 LRRC69 LRRIQ1 LRRC53 FLRT2

7.26e-041771567IPR003591
DomainSer/Thr_kinase_AS

CDK20 TNIK GAK MINK1 MAPKAPK5 TAOK2 STK3 BMPR2 BUB1B MAP4K4

8.54e-0435715610IPR008271
DomainSpectrin

SPTBN2 SYNE2 MACF1

8.95e-04231563PF00435
DomainNTR

C3 NTN1 PCOLCE

8.95e-04231563PS50189
DomainACTININ_2

SPTBN2 SYNE2 MACF1

8.95e-04231563PS00020
DomainACTININ_1

SPTBN2 SYNE2 MACF1

8.95e-04231563PS00019
DomainActinin_actin-bd_CS

SPTBN2 SYNE2 MACF1

8.95e-04231563IPR001589
DomainNetrin_domain

C3 NTN1 PCOLCE

8.95e-04231563IPR001134
DomainPROTEIN_KINASE_ST

CDK20 TNIK GAK MINK1 MAPKAPK5 TAOK2 STK3 BMPR2 BUB1B MAP4K4

9.49e-0436215610PS00108
Domain-

EVPL MACF1

1.02e-03615623.90.1290.10
DomainUmuC

ESCO1 POLK

1.02e-0361562IPR001126
DomainTIMP-like_OB-fold

C3 NTN1 PCOLCE

1.29e-03261563IPR008993
DomainPkinase

CDK20 TNIK GAK MINK1 MAPKAPK5 TAOK2 STK3 BMPR2 BUB1B MAP4K4

1.39e-0338115610PF00069
PathwayWP_HIPPOYAP_SIGNALING

TNIK MINK1 STK3 MAP4K4

3.24e-05221204M39821
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

JCAD HIVEP1 ARHGEF28 TCF20 ARHGEF5 MINK1 ANKRD26 VIRMA CIC STK3 CCDC88C BMPR2 PLEKHG3 SYNE2 BUB1B TJP2 MACF1 MAP4K4 YTHDF2 CEP170B PCM1

4.88e-108611592136931259
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

TNIK GAK TTLL5 MINK1 SPTBN2 BAG2 ANKRD26 TRAPPC8 TRIM27 PLXNB2 BRAP PCF11 LMAN1 ERAP2 VANGL1 SYNE2 BUB1B MACF1 ALAS1 NOP2 MAP4K4 PCM1 ATP6V0A2 FTSJ3

8.00e-0814871592433957083
Pubmed

YTHDF2 suppresses the plasmablast genetic program and promotes germinal center formation.

YTHDF1 YTHDF2 YTHDF3

9.38e-083159335508130
Pubmed

A Unified Model for the Function of YTHDF Proteins in Regulating m6A-Modified mRNA.

YTHDF1 YTHDF2 YTHDF3

9.38e-083159332492408
Pubmed

m6A-binding YTHDF proteins promote stress granule formation.

YTHDF1 YTHDF2 YTHDF3

9.38e-083159332451507
Pubmed

YTHDF3 facilitates translation and decay of N6-methyladenosine-modified RNA.

YTHDF1 YTHDF2 YTHDF3

9.38e-083159328106072
Pubmed

m6A enhances the phase separation potential of mRNA.

YTHDF1 YTHDF2 YTHDF3

9.38e-083159331292544
Pubmed

Comprehensive Analysis of YTH Domain Family in Lung Adenocarcinoma: Expression Profile, Association with Prognostic Value, and Immune Infiltration.

YTHDF1 YTHDF2 YTHDF3

9.38e-083159334497675
Pubmed

N(6)-methyladenosine of HIV-1 RNA regulates viral infection and HIV-1 Gag protein expression.

YTHDF1 YTHDF2 YTHDF3

9.38e-083159327371828
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

TNIK GAK BRIP1 TCF20 CENPE BAG2 BRAP YTHDF1 ZNF792 VANGL1 TJP2 EXOC7 MAP4K4 YTHDF2 YTHDF3 PCM1

2.88e-077331591634672954
Pubmed

N6-methyladenosine-dependent regulation of messenger RNA stability.

YTHDF1 YTHDF2 YTHDF3

3.74e-074159324284625
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

TNIK TPR TCF20 CENPE MINK1 SPTBN2 PEX5L GRM5 VIRMA TAOK2 CCDC88C SYNE2 DZIP3 MACF1 NOP2 MAP4K4 CEP170B PCM1

4.87e-079631591828671696
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

ARHGEF28 SPTBN2 ANKRD26 TRAPPC8 TUBGCP5 ESCO1 PCF11 CCDC88C AARS2 PLEKHG3 MACF1 FLRT2 EXOC7

4.91e-074931591315368895
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

TPR RAD18 BRIP1 HIVEP1 TCF20 MINK1 VIRMA CIC PPL PCF11 RBM6 TJP2 NOP2 MAP4K4 KDM6A PCM1

5.92e-077741591615302935
Pubmed

Context-dependent functional compensation between Ythdf m6A reader proteins.

YTHDF1 YTHDF2 YTHDF3

9.31e-075159332943573
Pubmed

m6A regulation of cortical and retinal neurogenesis is mediated by the redundant m6A readers YTHDFs.

TFAP2A YTHDF1 YTHDF2 YTHDF3

1.55e-0619159436039295
Pubmed

A human MAP kinase interactome.

TPR HIVEP1 TCF20 SPTBN2 EVPL MAPKAPK5 CIC ZNF440 RASAL3 MACF1 BICRAL MAP4K4

2.70e-064861591220936779
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

EFCAB6 MINK1 ANKRD26 PLXND1 PPL PCF11 IGBP1 LIPE VANGL1 TJP2 FLRT2 NOP2 ANO3 PCM1 ATP6V0A2

3.13e-067771591535844135
Pubmed

Planar cell polarity induces local microtubule bundling for coordinated ciliary beating.

FZD6 CCDC88C VANGL1

3.24e-067159333929515
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

GAK RAD18 HIVEP1 CENPE ANKRD26 CIC BRAP RBM6 MACF1 POLK CEP170B YTHDF3 PCM1

3.43e-065881591338580884
Pubmed

The m6A reader YTHDF2 is a negative regulator for dendrite development and maintenance of retinal ganglion cells.

TFAP2A YTHDF1 YTHDF2 YTHDF3

4.16e-0624159435179492
Pubmed

The Maternal Microbiome Programs the m6A Epitranscriptome of the Mouse Fetal Brain and Intestine.

YTHDF1 SULF1 YTHDF2 YTHDF3

4.94e-0625159435874829
Pubmed

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

TPR RAD18 CENPE TUBGCP5 ESCO1 TRIM5 PPL TUFT1 PCF11 STK3 FZR1 IGBP1 BUB1B LSM14A KCTD2 NOP2 CEP170B PCM1

6.23e-0611551591820360068
Pubmed

Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia.

TNIK ZNF10 MACF1 BICRAL EXOC1 SPARCL1 EXOC7

6.50e-06151159717043677
Pubmed

N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.

TPR GAK EVPL PPL AARS2 GSDMD TJP2 MACF1 LSM14A EXOC1

6.79e-063601591033111431
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

JCAD BAG2 ANKRD26 TRIM27 STK3 CCDC88C IGBP1 TJP2 MAP4K4 CEP170B PCM1

7.20e-064461591124255178
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

TPR RAD18 BRIP1 HIVEP1 TCF20 LYAR TFAP2A CIC PCF11 YTHDF1 RBM6 NOP2 YTHDF2 YTHDF3 PCM1 FTSJ3

8.56e-069541591636373674
Pubmed

Human transcription factor protein interaction networks.

RAD18 HIVEP1 DET1 TCF20 BAG2 SOX17 INO80D CIC PCF11 YTHDF1 TADA1 SYNE2 RBM6 LSM14A NOP2 KDM6A YTHDF2 YTHDF3 PCM1 FTSJ3

9.03e-0614291592035140242
Pubmed

Systematic analysis of dimeric E3-RING interactions reveals increased combinatorial complexity in human ubiquitination networks.

RAD18 MARCHF7 TRIM27 TRIM5 BRAP DZIP3

9.20e-06105159622493164
Pubmed

The human cytoplasmic dynein interactome reveals novel activators of motility.

TNIK JCAD CENPE TTLL5 SPTBN2 ANKRD26 LYAR CCDC88C BUB1B TJP2 MAP4K4 YTHDF2 CEP170B PCM1 FTSJ3

9.53e-068531591528718761
Pubmed

Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.

GARIN5B HIVEP1 TCF20 ZNF440 YTHDF1 AARS2 EXOC1 CCDC33

1.28e-05233159837704626
Pubmed

USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.

TPR CENPE MINK1 TRIM27 VIRMA MACF1 NOP2 UTY

1.32e-05234159836243803
Pubmed

Quantitative proteomics identifies the Myb-binding protein p160 as a novel target of the von Hippel-Lindau tumor suppressor.

VHL LYAR NOP2

1.51e-0511159321386990
Pubmed

Mettl14-mediated m6A modification ensures the cell-cycle progression of late-born retinal progenitor cells.

BRIP1 YTHDF1 YTHDF2 YTHDF3

1.97e-0535159437269288
Pubmed

Deletion of YTHDF1 (not YTHDF3) reduced brain and gut damage after traumatic brain injury.

YTHDF1 YTHDF3

2.08e-052159239081030
Pubmed

The interaction between mitotic checkpoint proteins, CENP-E and BubR1, is diminished in epothilone B-resistant A549 cells.

CENPE BUB1B

2.08e-052159220237434
Pubmed

Subcellular distribution of envoplakin and periplakin: insights into their role as precursors of the epidermal cornified envelope.

EVPL PPL

2.08e-052159211062259
Pubmed

An H-YDb epitope is encoded by a novel mouse Y chromosome gene.

KDM6A UTY

2.08e-05215928944031
Pubmed

N6-methyladenosine regulates maternal RNA maintenance in oocytes and timely RNA decay during mouse maternal-to-zygotic transition.

VIRMA YTHDF2

2.08e-052159235606490
Pubmed

CENP-E--dependent BubR1 autophosphorylation enhances chromosome alignment and the mitotic checkpoint.

CENPE BUB1B

2.08e-052159222801780
Pubmed

N(6)-methyladenosine Modulates Messenger RNA Translation Efficiency.

YTHDF1 YTHDF2

2.08e-052159226046440
Pubmed

m6A RNA modification and its writer/reader VIRMA/YTHDF3 in testicular germ cell tumors: a role in seminoma phenotype maintenance.

VIRMA YTHDF3

2.08e-052159230866959
Pubmed

Microtubule capture by CENP-E silences BubR1-dependent mitotic checkpoint signaling.

CENPE BUB1B

2.08e-052159216144904
Pubmed

Effect of dietary energy and polymorphisms in BRAP and GHRL on obesity and metabolic traits.

GHRL BRAP

2.08e-052159227245511
Pubmed

Brap regulates liver morphology and hepatocyte turnover via modulation of the Hippo pathway.

STK3 BIN2

2.08e-052159235476518
Pubmed

Co-assembly of envoplakin and periplakin into oligomers and Ca(2+)-dependent vesicle binding: implications for cornified cell envelope formation in stratified squamous epithelia.

EVPL PPL

2.08e-052159215033990
Pubmed

Cytoplasmic m6A reader YTHDF3 promotes mRNA translation.

YTHDF1 YTHDF3

2.08e-052159228106076
Pubmed

Detection of anti-envoplakin and anti-periplakin autoantibodies by ELISA in patients with paraneoplastic pemphigus.

EVPL PPL

2.08e-052159218820940
Pubmed

YTHDF1 and YTHDF2 are associated with better patient survival and an inflamed tumor-immune microenvironment in non-small-cell lung cancer.

YTHDF1 YTHDF2

2.08e-052159234408926
Pubmed

Sex-specific differences in expression of histone demethylases Utx and Uty in mouse brain and neurons.

KDM6A UTY

2.08e-052159218434530
Pubmed

The mechanism underlying redundant functions of the YTHDF proteins.

YTHDF1 YTHDF2

2.08e-052159236694229
Pubmed

YTHDF2/3 Are Required for Somatic Reprogramming through Different RNA Deadenylation Pathways.

YTHDF2 YTHDF3

2.08e-052159232905781
Pubmed

Target sequencing and CRISPR/Cas editing reveal simultaneous loss of UTX and UTY in urothelial bladder cancer.

KDM6A UTY

2.08e-052159227533081
Pubmed

Positive and negative selection on mammalian Y chromosomes.

KDM6A UTY

2.08e-052159215758204
Pubmed

Lysine demethylases KDM6A and UTY: The X and Y of histone demethylation.

KDM6A UTY

2.08e-052159231097364
Pubmed

Interaction of periplakin and envoplakin with intermediate filaments.

EVPL PPL

2.08e-052159212432088
Pubmed

Plexin-B2 and Plexin-D1 in dendritic cells: expression and IL-12/IL-23p40 production.

PLXND1 PLXNB2

2.08e-052159222916243
Pubmed

The KDM6A-SPARCL1 axis blocks metastasis and regulates the tumour microenvironment of gastrointestinal stromal tumours by inhibiting the nuclear translocation of p65.

SPARCL1 KDM6A

2.08e-052159235136209
Pubmed

Elucidation of the BMI1 interactome identifies novel regulatory roles in glioblastoma.

TPR BAG2 EVPL TRAPPC8 RBM6 LSM14A NOP2 CEP170B FTSJ3

2.23e-05329159934316702
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

JCAD MINK1 SPTBN2 BAG2 TFAP2A CIC PCF11 PTPN6 IGBP1 LMAN1 PTPRK VANGL1 SSH3 SYNE2 KDM6A FTSJ3

2.72e-0510491591627880917
Pubmed

A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.

SPOUT1 MINK1 ANKRD26 TRIM27 TFAP2A YTHDF1 STK3 TJP2 MACF1 EXOC1 NOP2 YTHDF2 YTHDF3

3.09e-057241591336232890
Pubmed

Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.

SPTBN2 PLXND1 TAOK2 AARS2 MACF1 BICRAL

3.10e-05130159612421765
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

TPR RAD18 SPOUT1 MARCHF7 UNC13D COX18 TRIM5 THOP1 DZIP3 TJP2 MACF1 BIN2 POLK BTG4 YTHDF3 ATP6V0A2

4.03e-0510841591611544199
Pubmed

Rap2A links intestinal cell polarity to brush border formation.

TNIK MINK1 MAP4K4

4.10e-0515159322797597
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

TPR GAK TCF20 SPTBN2 TFAP2A BRAP BUB1B TJP2 MAP4K4 KDM6A PCM1

4.85e-055491591138280479
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

TTLL5 PLXNB2 CIC SYNE2 BICRAL

5.12e-0587159512465718
Pubmed

Hypoxia and cell cycle regulation of the von Hippel-Lindau tumor suppressor.

VHL FZR1

6.21e-053159220802534
Pubmed

The association of metabotropic glutamate receptor type 5 with the neuronal Ca2+-binding protein 2 modulates receptor function.

NECAB2 GRM5

6.21e-053159219694902
Pubmed

Somatic mutations in planar cell polarity genes in neural tissue from human fetuses with neural tube defects.

FZD6 VANGL1

6.21e-053159232356230
Pubmed

Epidermal barrier defects link atopic dermatitis with altered skin cancer susceptibility.

EVPL PPL

6.21e-053159224843010
Pubmed

C3, hormone-sensitive lipase, and peroxisome proliferator-activated receptor gamma expression in adipose tissue of familial combined hyperlipidemia patients.

LIPE C3

6.21e-053159211979403
Pubmed

Plasma acylation-stimulating protein, adiponectin, leptin, and ghrelin before and after weight loss induced by gastric bypass surgery in morbidly obese subjects.

GHRL C3

6.21e-053159212679444
Pubmed

m6A modification controls the innate immune response to infection by targeting type I interferons.

YTHDF2 YTHDF3

6.21e-053159230559377
Pubmed

The UTX gene escapes X inactivation in mice and humans.

KDM6A UTY

6.21e-05315929499428
Pubmed

Characterization of the kinetochore binding domain of CENP-E reveals interactions with the kinetochore proteins CENP-F and hBUBR1.

CENPE BUB1B

6.21e-05315929763420
Pubmed

Periplakin, a novel component of cornified envelopes and desmosomes that belongs to the plakin family and forms complexes with envoplakin.

EVPL PPL

6.21e-05315929412476
Pubmed

The m6 A Readers YTHDF1 and YTHDF2 Synergistically Control Cerebellar Parallel Fiber Growth by Regulating Local Translation of the Key Wnt5a Signaling Components in Axons.

YTHDF1 YTHDF2

6.21e-053159234643063
Pubmed

Involvement of TFAP2A in the activation of GSDMD gene promoter in hyperoxia-induced ALI.

TFAP2A GSDMD

6.21e-053159233609534
Pubmed

Mannan-binding lectin activates C3 and the alternative complement pathway without involvement of C2.

LMAN1 C3

6.21e-053159216670774
Pubmed

KIAA1429 increases FOXM1 expression through YTHDF1-mediated m6A modification to promote aerobic glycolysis and tumorigenesis in multiple myeloma.

VIRMA YTHDF1

6.21e-053159239060874
Pubmed

SUMOylation of TUFT1 is essential for gastric cancer progression through AKT/mTOR signaling pathway activation.

TRIM27 TUFT1

6.21e-053159236380570
Pubmed

Increased Bacterial Load and Expression of Antimicrobial Peptides in Skin of Barrier-Deficient Mice with Reduced Cancer Susceptibility.

EVPL PPL

6.21e-053159226763429
Pubmed

YTH: a new domain in nuclear proteins.

YTHDF2 YTHDF3

6.21e-053159212368078
Pubmed

Gene amplification-driven RNA methyltransferase KIAA1429 promotes tumorigenesis by regulating BTG2 via m6A-YTHDF2-dependent in lung adenocarcinoma.

VIRMA YTHDF2

6.21e-053159235730068
Pubmed

The hBUB1 and hBUBR1 kinases sequentially assemble onto kinetochores during prophase with hBUBR1 concentrating at the kinetochore plates in mitosis.

CENPE BUB1B

6.21e-05315929914370
Pubmed

Erythroid-specific 5-aminolevulinate synthase protein is stabilized by low oxygen and proteasomal inhibition.

VHL ALAS1

6.21e-053159216234850
Pubmed

The kinetochore proteins CENP-E and CENP-F directly and specifically interact with distinct BUB mitotic checkpoint Ser/Thr kinases.

CENPE BUB1B

6.21e-053159229748388
Pubmed

Centromere-associated protein-E is essential for the mammalian mitotic checkpoint to prevent aneuploidy due to single chromosome loss.

CENPE BUB1B

6.21e-053159212925705
Pubmed

Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq.

YTHDF2 YTHDF3

6.21e-053159222575960
Pubmed

MINK is a Rap2 effector for phosphorylation of the postsynaptic scaffold protein TANC1.

TNIK MINK1

6.21e-053159218930710
Pubmed

Germinal Cell Aplasia in Kif18a Mutant Male Mice Due to Impaired Chromosome Congression and Dysregulated BubR1 and CENP-E.

CENPE BUB1B

6.21e-053159220981276
Pubmed

E-cadherin interactome complexity and robustness resolved by quantitative proteomics.

JCAD MINK1 SPTBN2 EVPL PPL BMPR2 IGBP1 PROM2 SSH3 TJP2 MACF1

6.27e-055651591125468996
Pubmed

Analysis of the human E2 ubiquitin conjugating enzyme protein interaction network.

RAD18 MARCHF7 TRIM27 TRIM5 BRAP DZIP3

6.65e-05149159619549727
Pubmed

The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis.

TNIK YTHDF1 DZIP3 EXOC1 MAP4K4 CEP170B PCM1

6.88e-05218159733378226
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

TPR TCF20 SPTBN2 BAG2 PLXNB2 AARS2 PLEKHG3 VANGL1 SYNE2 TJP2 MACF1 NOP2 MAP4K4 PCM1 FTSJ3

7.71e-0510241591524711643
Pubmed

Endogenous Cell Type-Specific Disrupted in Schizophrenia 1 Interactomes Reveal Protein Networks Associated With Neurodevelopmental Disorders.

TNIK VIRMA AARS2 RBM6 TJP2 MAP4K4

8.58e-05156159629961565
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

JCAD SETMAR TTLL5 SPTBN2 CMYA5 TUBGCP5 TRIM5 THOP1 PTPRK SULF1 MACF1 EXOC1 SPARCL1 EXOC7 MAP4K4 KDM6A PCM1

8.84e-0512851591735914814
Pubmed

Interactome Analysis of the Nucleocapsid Protein of SARS-CoV-2 Virus.

SPOUT1 BAG2 LYAR MACF1 NOP2 FTSJ3

9.52e-05159159634578187
Pubmed

An extracellular biochemical screen reveals that FLRTs and Unc5s mediate neuronal subtype recognition in the retina.

PLXND1 PLXNB2 NTN1 FLRT2

9.60e-0552159426633812
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

TNIK TPR GAK ANKRD26 CIC BRAP IGBP1 BUB1B MACF1 LSM14A NOP2 YTHDF2 PCM1 FTSJ3

1.06e-049341591433916271
InteractionTNIK interactions

TNIK TPR MINK1 SPTBN2 BAG2 PEX5L GRM5 VIRMA TAOK2 SYNE2 MACF1 MAP4K4 CEP170B PCM1

1.92e-0638115814int:TNIK
InteractionSTRN interactions

TNIK MINK1 BAG2 VIRMA TUFT1 STK3 EXOC1 MAP4K4 PCM1

3.58e-061541589int:STRN
InteractionHCN1 interactions

TNIK GLTP SPTBN2 EVPL PEX5L PPL C3

2.29e-051081587int:HCN1
InteractionBICD1 interactions

TNIK JCAD CENPE ANKRD26 VIRMA CCDC88C TJP2 C3 CEP170B PCM1

2.89e-0525015810int:BICD1
InteractionFNDC1 interactions

EVPL PPL FZR1 C3

3.42e-05241584int:FNDC1
InteractionDISC1 interactions

TNIK BAG2 TRIM27 VIRMA AARS2 RBM6 TJP2 MACF1 EXOC1 SPARCL1 EXOC7 MAP4K4 PCM1

3.48e-0542915813int:DISC1
InteractionSMG7 interactions

HIVEP1 DET1 TCF20 PCF11 YTHDF1 RBM6 TJP2 LSM14A YTHDF2 YTHDF3 PCM1

4.49e-0531915811int:SMG7
InteractionTDRD3 interactions

TNIK BAG2 YTHDF1 DZIP3 TJP2 LSM14A KCTD2 YTHDF2 YTHDF3

4.62e-052121589int:TDRD3
GeneFamilyEF-hand domain containing|Plakins

EVPL PPL MACF1

9.28e-0681013939
GeneFamilyExocyst complex

EXOC1 EXOC7

1.08e-03910121055
GeneFamilyPlexins

PLXND1 PLXNB2

1.08e-0391012683
ToppCellLPS_only-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_only / Treatment groups by lineage, cell group, cell type

ARHGEF28 OLFML2B PLXNB2 LIPE LMAN1 SYNE2 C3 ALAS1 GALNT5 CLNK

2.49e-09197159101a1bee8da6e04b65935c40373eaee4d6c046d9a1
ToppCellLPS_IL1RA-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

ARHGEF28 OLFML2B PLXNB2 LIPE LMAN1 C3 ALAS1 GALNT5 CLNK

4.15e-081981599285f729140b1df029c24f6ca1d2438470ac51794
ToppCelldroplet-Heart-nan-3m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TPR ECM2 CMYA5 ESCO1 BMPR2 MACF1 KDM6A PCM1

2.40e-071761598749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

ARHGEF28 PLXNB2 LIPE LMAN1 C3 ALAS1 GALNT5 CLNK

5.64e-0719715981485933986921ff45669d9b7501c8d17050b3e97
ToppCellLPS_only-Epithelial_alveolar-AT_2|LPS_only / Treatment groups by lineage, cell group, cell type

ARHGEF28 OLFML2B PLXNB2 LMAN1 C3 ALAS1 GALNT5 CLNK

5.86e-071981598d087e738d69ca9853553fde46d4e7a8906439d32
ToppCellLPS_only-Epithelial_alveolar|LPS_only / Treatment groups by lineage, cell group, cell type

OLFML2B PLXNB2 LMAN1 SYNE2 C3 ALAS1 GALNT5 CLNK

5.86e-071981598655df75b9692d815c7f6910275e1f684ac63bf62
ToppCellmetastatic_Brain-Fibroblasts-FB-like_cells|metastatic_Brain / Location, Cell class and cell subclass

JCAD ASPN ECM2 ADAM12 SULF1 SPARCL1 FLRT2 PCOLCE

6.09e-07199159812133087eae9f0e9b6c13a71e8187117768e64ce
ToppCell3'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

JCAD ASPN OLFML2B ECM2 C3 SPARCL1 FLRT2 PCOLCE

6.09e-0719915989846d6a31635fde759d55674631c11ab9270a603
ToppCellNS-control|NS / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ARHGEF28 EVPL PLXNB2 PPL PTPRK SYNE2 TJP2 SPARCL1

6.33e-072001598ecbe89ff95d046155b984c8c150e0b9e7278f839
ToppCellPericytes-IPF_04|World / lung cells shred on cell class, cell subclass, sample id

ZNF577 ASPN OLFML2B ECM2 BAG2 SULF1 SPARCL1

1.16e-061501597dbc202bd6db4fb5c8b2abd1200e074a2a9e63a59
ToppCellInt-URO-Lymphocyte-T_NK-CD4_CTL|Int-URO / Disease, Lineage and Cell Type

TNIK BRIP1 LYAR CATSPER2 SYNE2 MDGA1 CEP170B

1.33e-061531597fdc7dfa8f4db90bfdc7180bf178cf6d2dd064d97
ToppCellPND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

EVPL PPL SULF1 SYNE2 C3 FLRT2 PCOLCE

2.38e-061671597c042d6cdddd0e1ddef1e3ac6f4fe23151127b0f2
ToppCellPND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

EVPL PPL SULF1 SYNE2 C3 FLRT2 PCOLCE

2.38e-061671597351f8de1fbdf742ac74f9099b254d515ab539bb2
ToppCellIIH-CD8-naive_CD4|IIH / Condition, Cell_class and T cell subcluster

TSHR ESCO1 ZNF10 ZNF792 ALAS1 FLRT2 ATP6V0A2

3.00e-0617315974f2843371d18af766c1892529ce286f56c956fde
ToppCell10x_3'_v3-thymus_(10x_3'_v3)-lymphocytic-T_lymphocytic-mature_NK_T_cell|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

EMB LYAR CCDC88C PLEKHG3 SYNE2 MACF1 BIN2

3.00e-06173159736a471576a9d2325066bb14c2f2cd89c67b92915
ToppCellLPS_only-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARHGEF28 OLFML2B PLXNB2 SYNE2 C3 GALNT5 CLNK

3.76e-061791597fd2cbee532e7b44113410dca82aec7db1a7fb69f
ToppCellControl-Epithelial-Basal|Control / Disease state, Lineage and Cell class

TFAP2A PPL PTPRK SULF1 ASXL3 NTN1 GALNT5

4.20e-061821597caddd0a52f0234ea6a916186ffaf2454cdcd80ee
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGEF28 SPTBN2 PPL SHOC1 NTN1 SPARCL1 CLNK

4.84e-061861597a6ef5d5944af5689b5f27bef89cd05645eedbe50
ToppCell10x3'2.3-week_17-19-Endothelial-stroma-proliferating_EC|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

JCAD ARHGEF28 SOX17 PLXND1 FZD6 ZNF792 SPARCL1

4.84e-061861597a844d4f79e0ad5d6c60a4488ffd8f4f21b7eed04
ToppCellTCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Ductal_Carcinoma-6|TCGA-Breast / Sample_Type by Project: Shred V9

JCAD ASPN OLFML2B ADAM12 SULF1 SPARCL1 GALNT5

5.01e-061871597a96495803ba13fcfadd1d83b3cf5774f3fed0a20
ToppCell(2)_Fibroblasts-(20)_Fibro-1|World / Cell class and subclass of bone marrow stroma cells in homeostatis

ASPN OLFML2B PPL C3 NTN1 FLRT2 PCOLCE

5.19e-061881597409a7b69d02e87084ca955e3fe6c77230dee8861
ToppCell10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8|lymph-node_spleen / Manually curated celltypes from each tissue

TNIK ZNF10 SYNE2 MACF1 KDM6A UTY PCM1

5.96e-06192159747646d7e4990be85072987f92bf18d52f8da752e
ToppCellfacs-Lung-nan-3m-Mesenchymal|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ASPN OLFML2B ECM2 SULF1 C3 FLRT2 PCOLCE

6.17e-061931597d9c20a092b507c43fcf7ccb04073fecd27d1749c
ToppCell3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ASPN OLFML2B ECM2 C3 SPARCL1 FLRT2 PCOLCE

6.38e-06194159735b30bc954750e939f81a9a7498b8bc2ce69a299
ToppCellPCW_13-14-Epithelial-Epithelial_proliferating-epi_proliferating3_(5)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

ARHGEF28 EVPL ADCY8 PPL TUFT1 FZD6 LRRIQ1

6.38e-061941597c011cd59bb4ca4134331cba0f5d73bdbd7011d64
ToppCelldroplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l1|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

JCAD OLFML2B SULF1 C3 NTN1 SPARCL1 PCOLCE

6.38e-061941597ff19fb5bc7feae3e774ef4ab720beb9dec219f45
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c04-ANXA2|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

TNIK LRRC8C TP53INP1 EMB IGBP1 SYNE2 BIN2

6.60e-061951597e06ff785c5542c86c335d956799e03f7ae8345a4
ToppCellfacs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l1|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ASPN OLFML2B ECM2 SULF1 C3 SPARCL1 PCOLCE

6.60e-061951597773728703bc8969bff0e1de58fe3e1631add0a0a
ToppCellfacs-Trachea-18m-Mesenchymal|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ASPN OLFML2B ECM2 SULF1 C3 SPARCL1 PCOLCE

6.60e-0619515970d1876f6fdc1eafeb60d6fd7da5bce737d2b4a5a
ToppCelldroplet-Mammary_Gland-nan-3m-Epithelial-luminal_progenitor_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGEF5 TFAP2A PPL PLEKHG3 TJP2 NTN1 CEP170B

6.82e-06196159722fcfb713f402ebbd43b2822f0fd919cdbfba6e4
ToppCellPCW_13-14-Epithelial-Epithelial_proliferating|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

ARHGEF28 EVPL ADCY8 PPL TUFT1 FZD6 LRRIQ1

6.82e-0619615977b17d47b7758d8ccf9dbefd097aeb553791a1eed
ToppCellfacs-Aorta-Heart-3m-Mesenchymal-fibroblast_of_cardiac_tissue|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OLFML2B PLXNB2 PPL C3 NTN1 FLRT2 PCOLCE

6.82e-0619615972029f58ce6a7b8c35d3a7496c3341391990909ce
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

EMB LYAR RASAL3 SYNE2 DZIP3 BIN2 PCM1

7.05e-0619715972e9677b4b9a7c88db16416e5f114a2031ec3bc24
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

EMB LYAR RASAL3 SYNE2 DZIP3 BIN2 PCM1

7.05e-0619715974c9919914079e76b1d2220b249e0d0b0d9bf4bc0
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

EFCAB6 ANKRD26 ARMC2 ZNF440 LRRIQ1 SYNE2 CCDC180

7.05e-06197159774a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCell5'-Adult-Appendix-Endothelial-blood_vessel_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

JCAD SOX17 PLXND1 BMPR2 SULF1 SYNE2 SPARCL1

7.05e-061971597e8e879b7634a29569061d3515d180784094a31e7
ToppCell3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ASPN OLFML2B ECM2 SULF1 SPARCL1 FLRT2 PCOLCE

7.05e-0619715976b6440f1baad5680cf9e13ca3ab72a2c65523d59
ToppCellSepsis-ICU-SEP-Lymphocyte-T/NK-Treg|ICU-SEP / Disease, condition lineage and cell class

TPR DET1 ARHGEF5 ADAM12 LMAN1 SYNE2 CLNK

7.05e-061971597c3ee2d522fbfe67069ddba2d1abfc4f5ca230c26
ToppCelldroplet-Bladder-nan-24m-Epithelial-bladder_mesenchymal_cell_(Scara5+)|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OLFML2B SULF1 C3 NTN1 SPARCL1 FLRT2 PCOLCE

7.29e-061981597d4f74320ea6c1a7e568ee5bc48bb66cb45e1004d
ToppCellT_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

TNIK EMB CCDC88C RASAL3 SYNE2 MACF1 BIN2

7.29e-0619815971ca6cd8e75891fdfaddbb4a7342eec9ca4d11e5d
ToppCell5'-Adult-Distal_Rectal-Endothelial-blood_vessel_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

JCAD SOX17 PLXND1 FZD6 BMPR2 SULF1 SPARCL1

7.29e-061981597d1f54ed3ef5e05ebda7da999e172d168dc6802cd
ToppCell5'-Adult-Distal_Rectal-Endothelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

JCAD SOX17 PLXND1 FZD6 BMPR2 SULF1 SPARCL1

7.29e-0619815978d6b0b9da7c1e64155cbcbb04ad38d129a29030c
ToppCellSepsis-Int-URO-Lymphocyte-T/NK-CD4+_CTL|Int-URO / Disease, condition lineage and cell class

TNIK BRIP1 LYAR CATSPER2 SYNE2 MDGA1 CEP170B

7.29e-061981597717735d755745439f97ba1b71785c73945dfa9c5
ToppCell10x_3'_v3-spleen_(10x_3'_v3)-lymphocytic-T_lymphocytic-naive_thymus-derived_CD8-positive,_alpha-beta_T_cell|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

LRRC8C EMB LYAR CCDC88C LINC00869 SYNE2 BIN2

7.53e-061991597db05c16d80f5a74bfa048a5c92917d312d26f769
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

JCAD SOX17 PLXND1 BMPR2 ARAP3 SPARCL1 FLRT2

7.53e-061991597f35e9c05d0a0339ff691b38564da7aad8e9218aa
ToppCellSepsis-ICU-NoSEP-Lymphocyte-T/NK-dn_T|ICU-NoSEP / Disease, condition lineage and cell class

LYAR FZD6 SEPHS2 VANGL1 SYNE2 DZIP3 CDADC1

7.53e-0619915977fb211f803a8b3a2cfa9455386abea08131c6b52
ToppCellcellseq-Mesenchymal-Fibroblastic-Fibroblastic_1-AF2|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ASPN ECM2 SULF1 C3 SPARCL1 FLRT2 PCOLCE

7.78e-06200159728e5354008adf97b17333f17f8cbef930db6729a
ToppCellcontrol|World / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

ARHGEF28 EVPL PLXNB2 PPL SYNE2 TJP2 SPARCL1

7.78e-06200159797f36d2c197e03d93a1fc59949d77ae90f6e6a9a
ToppCellLPS_only-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_only / Treatment groups by lineage, cell group, cell type

UNC13D PLXNB2 SYNE2 C3 ALAS1 GALNT5 CEP170B

7.78e-0620015972dadf317a42a7e27cc1fac74f91b806c93a57108
ToppCell5'-Adult-SmallIntestine-Endothelial-blood_vessel_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

JCAD SOX17 PLXND1 BMPR2 ARAP3 SULF1 SPARCL1

7.78e-062001597cd3c638961144a2fc91c437a173cc37c7452fa74
ToppCellCOVID-19-COVID-19_Severe-Lymphocyte-T/NK-gd_T|COVID-19_Severe / Disease, condition lineage and cell class

TNIK LYAR ADAM12 CCDC88C PLEKHG3 SYNE2 MACF1

7.78e-062001597f72bc3f6606ae77fe1b0a972e35b3ce0727804d9
ToppCellcellseq-Mesenchymal-Fibroblastic-Fibroblastic_1|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ASPN ECM2 SULF1 C3 SPARCL1 FLRT2 PCOLCE

7.78e-06200159756536236a7012efdb28f85b40e464f3da3e87ce8
ToppCellAdult-Epithelial-basal_cell-D122|Adult / Lineage, Cell type, age group and donor

CMYA5 TFAP2A SULF1 ASXL3 BUB1B NTN1

1.93e-05154159638d346402417960044ae999e61f0092b46f2b591
ToppCellVE-Treg-naive_CD4|VE / Condition, Cell_class and T cell subcluster

CACNB3 RAD18 ANKRD26 PPL ARAP3 SYNE2

2.08e-0515615966501baf73616e702946de9fb13d267e30a68888b
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NECAB2 SPTBN2 TSHR LRRIQ1 SLC9B2 CCDC180

2.32e-05159159600a157d033627d0e65c3fbd38d652c4cf56b47f6
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6_CT|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

JCAD ARHGEF28 EMB OLFML2B CMYA5 ANO3

2.57e-05162159658da6bc04cdac0002b0e6a751c96ff95e1a7f70f
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6_CT-L6_CT_VISp_Ctxn3_Sla|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

JCAD EMB OLFML2B CMYA5 PEX5L ANO3

2.57e-0516215964d13c271b4f63cf32980e5643b5d5951165fe8b5
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6_CT-L6_CT_VISp_Ctxn3_Brinp3|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

JCAD ARHGEF28 EMB OLFML2B CMYA5 ANO3

2.66e-051631596b0aa4a620bd58011225b42ea6dda04e3101ba342
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c04-ANXA2|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

CDK20 TNIK LRRC8C EFCAB6 LYAR ADAM12

2.76e-0516415968f3255d7f67890389a768453492243ea982eb38a
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SOX17 PLXND1 FZD6 SULF1 SYNE2 FLRT2

2.95e-0516615967a45785a40b7425f97be67bab1c5ceb69b2bd85a
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SOX17 PLXND1 FZD6 SULF1 SYNE2 FLRT2

2.95e-051661596bbd382812f8a84a5d99888de2d7cca3a8b5e4695
ToppCelldroplet-Marrow-nan-24m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNB3 GAK ARHGEF28 MINK1 TJP2 KDM6A

3.15e-051681596e979a4fbeb9f21048b47d69e6da75c57650697f2
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGEF28 SPTBN2 SHOC1 NTN1 SPARCL1 CLNK

3.26e-0516915964b3a7b4a497178799b6b2f0b744f5fb752cee31a
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGEF28 SPTBN2 SHOC1 NTN1 SPARCL1 CLNK

3.26e-051691596a4fd646b9bf87225131fca530bd6b52df9eaf489
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GRM5 ARMC2 ZNF440 CCDC88C LRRIQ1 DZIP3

3.26e-05169159614aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCellTCGA-Bladder-Primary_Tumor-Urothelial_Carcinoma-Non-Papillary_Muscle_Invasive_Urothelial_Carcinoma-9|TCGA-Bladder / Sample_Type by Project: Shred V9

PPL FZD6 PTPRK PROM2 VANGL1 GALNT5

3.48e-051711596adbcfa4bf6bc1c604535a24435924cdb091e2dd7
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_T-T4_reg-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

TPR TSHR SULF1 SYNE2 UTY PCM1

3.60e-0517215969497948bbe53fb88c6ff6b347f743d456da587e5
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6-Exc_L5-6_THEMIS_TMEM233|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ARHGEF28 PPL LRRIQ1 PTPRK MDGA1 ANO3

4.50e-051791596747a32460b257fffca30527b56a74720eb9c12e4
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GLTP SPTBN2 LRRC69 LMAN1 SHOC1 CLNK

4.50e-05179159627ad6a609fe1f7532b142d0147bccf918704a6dd
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Mesenchymal-Ependyma|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EMB ADAM12 LRRIQ1 C3 CCDC33 PCOLCE

4.64e-051801596729f0d7af573c7796d8e28e6eec3af2fc0bd33a2
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Mesenchymal-ependymal_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EMB ADAM12 LRRIQ1 C3 CCDC33 PCOLCE

4.64e-0518015969ef79a7c60227e352ac166c7274adb31f585f5ca
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

JCAD PEX5L ADAM12 LRRIQ1 PTPRK ANO3

4.78e-05181159658f76bb9ea1518c2b629a0256a3f6595a9278152
ToppCellfacs-Marrow-Granulocytes-3m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CENPE OLFML2B SYNE2 BUB1B C3 ALAS1

4.78e-051811596566249e04dd491e6287ad2101b7b1ab11031ed8b
ToppCellfacs-Marrow-Granulocytes-3m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CENPE OLFML2B SYNE2 BUB1B C3 ALAS1

4.78e-051811596db9528dc7cb0230e4c36cb27da69102c588c7ee9
ToppCellControl-Epithelial-Basal|World / Disease state, Lineage and Cell class

PPL PTPRK SULF1 ASXL3 NTN1 GALNT5

4.93e-051821596759390dde9b18757f7675d13d44c89d0e32f8d93
ToppCellfacs-Lung-nan-3m-Endothelial-Artery_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JCAD PLXND1 SULF1 NTN1 FLRT2 MAP4K4

5.08e-05183159612e876d6205af8aad74265c668b5e95b9e7487f3
ToppCell3'-Child04-06-SmallIntestine-Mesenchymal-fibroblastic-Stromal_4_(MMP1+)|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CACNB3 CMYA5 SULF1 C3 SPARCL1 PCOLCE

5.08e-051831596269afec240a756eec3bbae5f30ec784281af3433
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive|renal_medulla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

TNIK HIVEP1 ADAM12 MACF1 C3 KDM6A

5.24e-051841596d2bf0135eb56bb410997dccea39c5ede88a0617f
ToppCell5'-GW_trimst-2-LymphNode-Mesenchymal-fibroblastic-Stromal_3_(C7+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NECAB2 OLFML2B ECM2 ADAM12 FLRT2 PCOLCE

5.24e-0518415964d4d8f3f44c67d74c57e7af7b7c158f0157b2f49
ToppCellTCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Classical-4|TCGA-Thryoid / Sample_Type by Project: Shred V9

RAD18 SPTBN2 PCDHAC2 PPL TJP2 CEP170B

5.24e-051841596d9659d1e4465fec68f48a22edef443f354f6c7cf
ToppCellfacs-Mammary_Gland-Mammary_Gland-3m-Mesenchymal-stromal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ASPN OLFML2B ECM2 SPARCL1 FLRT2 PCOLCE

5.40e-0518515963cd0686a14e734a0f243070ab939adcb4c454478
ToppCellfacs-Mammary_Gland-Mammary_Gland-3m-Mesenchymal-stromal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ASPN OLFML2B ECM2 SPARCL1 FLRT2 PCOLCE

5.40e-05185159600258f458cbf6d36449db95528a6b5038d731d2d
ToppCellfacs-Mammary_Gland-Mammary_Gland-3m-Mesenchymal|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ASPN OLFML2B ECM2 SPARCL1 FLRT2 PCOLCE

5.40e-051851596a94694e226856bc5b168464f52d76004145717a5
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ASPN OLFML2B ECM2 ADAM12 SULF1 PCOLCE

5.40e-05185159687c416d14ca6255bee39b16e7571553e36ee3069
ToppCellCOPD-Lymphoid-T_Regulatory|COPD / Disease state, Lineage and Cell class

TNIK EMB ADAM12 CCDC88C SYNE2 CLNK

5.40e-051851596846403edd4c8f646201d519055198fc38b7ffff9
ToppCellnormal-na-Lymphocytic_T-CytoT_GZMH+-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

EMB LYAR VANGL1 SYNE2 MACF1 UTY

5.40e-051851596097d628f92e13250c15b550f2fd1f4225fc07558
ToppCellfacs-Pancreas-Exocrine-24m-Mesenchymal|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EFCAB6 SULF1 C3 SPARCL1 ANO3 PCOLCE

5.73e-0518715960f90bce2087aecfdbb377e6f46c6e468efbb6e28
ToppCellfacs-Pancreas-Exocrine-24m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EFCAB6 SULF1 C3 SPARCL1 ANO3 PCOLCE

5.73e-05187159676c957b2976d38adb45e07bcf96c689442e1fc20
ToppCellfacs-Pancreas-Exocrine-24m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EFCAB6 SULF1 C3 SPARCL1 ANO3 PCOLCE

5.73e-05187159690a1078b0303799fba5d2ca4fa12076fd75b78b1
ToppCellControl-T_cells|Control / group, cell type (main and fine annotations)

LRRC8C EMB CCDC88C RASAL3 SYNE2 BIN2

5.73e-051871596f4e8e0eba58da89b56587667555a5d4754e108c7
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARHGEF28 UNC13D PPL SYNE2 C3 GALNT5

5.73e-05187159658d48128547ee3513d0bf7f78e61b76b1c472ca9
ToppCelldroplet-Bladder-Unstain-18m-Epithelial-bladder_mesenchymal_cell_(Scara5+)|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SULF1 C3 NTN1 SPARCL1 FLRT2 PCOLCE

5.73e-0518715967beba2a5d5978f2ae7d8bde10815705cf2572211
ToppCellControl-Endothelial_cells-Arterial_endothelial_cells|Control / group, cell type (main and fine annotations)

JCAD SOX17 BMPR2 ARAP3 SULF1 SPARCL1

5.73e-05187159681affaab3fe3e1daea45ada6445e906ddd33950e
ToppCellfacs-Heart-LV-18m-Endothelial-endothelial_cell_of_coronary_artery|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRRC8C SOX17 PLXND1 LIPE ARAP3 TJP2

5.90e-051881596ed11e26ff4ef3d6314b5f5734062519b9aa285c1
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGEF28 SPTBN2 PPL NTN1 SPARCL1 CLNK

5.90e-051881596e751cff2ac8fbc1487766c1871fcc5d1005286b0
ToppCellfacs-Heart-LV-18m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRRC8C SOX17 PLXND1 LIPE ARAP3 TJP2

5.90e-051881596e5a8ca4613ab0bf1584b9e78959adf41d0bf379f
ToppCellfacs-Heart-LV-18m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRRC8C SOX17 PLXND1 LIPE ARAP3 TJP2

5.90e-0518815960fc3a6562e6895f6fe7a93397eae842a75c60c93
ToppCell10x3'2.3-week_17-19-Mesenchymal_osteo-stroma-osteochondral_precursor|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

ASPN OLFML2B ADAM12 SULF1 SPARCL1 PCOLCE

6.08e-0518915961ff4f8da572bdc6356e9df9f41a7f62c81d4c570
ToppCellControl-Epithelial-Basal/Club|Control / Disease group,lineage and cell class （2021.01.30）

EVPL PPL PTPRK PROM2 SPARCL1 GALNT5

6.26e-051901596799b0b1c4bdbe04ee0fc34d0be9e02b5992774a0
ToppCellfacs-Pancreas-Exocrine-3m-Endothelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JCAD SOX17 PLXND1 LIPE ARAP3 SPARCL1

6.26e-051901596b7fc451e160e31dc898b122de844b501f587db67
DrugMethotrimeprazine maleat salt [7104-38-3]; Down 200; 9uM; PC3; HT_HG-U133A

JCAD BRIP1 TTLL5 TFAP2A ZNF10 ARAP3 ERAP2 SSH3 DZIP3 CDADC1 EXOC7 UTY

1.36e-08198157127399_DN
DrugTetrandrine [518-34-3]; Down 200; 6.4uM; HL60; HT_HG-U133A

CACNB3 SPOUT1 TTLL5 MINK1 INO80D ZNF10 FZR1 SSH3 KCTD2 FLRT2

1.01e-06194157102520_DN
DrugChlorthalidone [77-36-1]; Down 200; 11.8uM; PC3; HT_HG-U133A

JCAD CACNB3 MINK1 BRAP STK3 CCDC88C SSH3 LSM14A KDM6A UTY

1.06e-06195157107152_DN
DrugRibavirin [36791-04-5]; Up 200; 16.4uM; PC3; HT_HG-U133A

TNIK CACNB3 MINK1 SPTBN2 PLXND1 TAOK2 FZR1 KHK KDM6A

9.13e-0619615797316_UP
DrugGramine [87-52-5]; Up 200; 23uM; PC3; HT_HG-U133A

TNIK OLFML2B PEX5L STK3 FZR1 LIPE SULF1 DZIP3 EXOC7

9.13e-0619615793999_UP
DrugCefazolin sodium salt [27164-46-1]; Down 200; 8.4uM; PC3; HT_HG-U133A

MINK1 SPTBN2 PLXND1 ADAM12 TAOK2 SSH3 LSM14A KHK UTY

9.13e-0619615793686_DN
DrugAzathioprine [446-86-6]; Down 200; 14.4uM; MCF7; HT_HG-U133A

CACNB3 MINK1 INO80D TRIM5 FZR1 THOP1 SSH3 DZIP3 KHK

9.90e-0619815795627_DN
DrugTrichlorfon [52-68-6]; Down 200; 15.6uM; HL60; HT_HG-U133A

MINK1 BRAP TAOK2 ZNF10 CCDC88C THOP1 C3 EXOC7 KDM6A

9.90e-0619815791839_DN
DrugGlibenclamide [10238-21-8]; Down 200; 8uM; PC3; HT_HG-U133A

JCAD ARHGEF28 TTLL5 EVPL TFAP2A BRAP PLEKHG3 SSH3 EXOC7

9.90e-0619815795849_DN
DrugAmitryptiline hydrochloride [549-18-8]; Up 200; 12.8uM; MCF7; HT_HG-U133A

JCAD ARHGEF28 TTLL5 ADAM12 INO80D FZR1 C3 UTY PCM1

9.90e-0619815795453_UP
Drugresveratrol; Down 200; 10uM; MCF7; HT_HG-U133A_EA

CENPE MARCHF7 TFAP2A PCF11 THOP1 PLEKHG3 SSH3 BUB1B

3.25e-051771578841_DN
Drugp-cymen-8-ol

BRIP1 SAGE1

4.72e-0521572CID000014529
Drugisocamphane

SYNE2 SAGE1

4.72e-0521572CID000296894
Drugpinocamphone

EMB SAGE1

4.72e-0521572CID000011038
DrugEconazole nitrate [24169-02-6]; Down 200; 9uM; PC3; HT_HG-U133A

BRIP1 TFAP2A PPL FZR1 LMAN1 DZIP3 LSM14A PCM1

5.38e-0519015787305_DN
DrugMethylprednisolone, 6-alpha [83-43-2]; Down 200; 10.6uM; PC3; HT_HG-U133A

HIVEP1 ARHGEF28 MARCHF7 TUBGCP5 PLXNB2 PPL BICRAL KDM6A

6.22e-0519415787137_DN
DrugDiethylstilbestrol [56-53-1]; Down 200; 15uM; PC3; HT_HG-U133A

TNIK CACNB3 OLFML2B ECM2 INO80D STK3 FZR1 LMAN1

6.45e-0519515783812_DN
DrugCloperastine hydrochloride [14984-68-0]; Down 200; 11uM; PC3; HT_HG-U133A

TNIK ANKRD26 ADAM12 TUBGCP5 BRAP FZR1 EXOC7 PCOLCE

6.45e-0519515783710_DN
DrugQuinidine hydrochloride monohydrate [6151-40-2]; Down 200; 10.6uM; MCF7; HT_HG-U133A

PLXND1 TAOK2 FZR1 SULF1 DZIP3 KHK ALAS1 KCTD2

6.45e-0519515783191_DN
DrugDiprophylline [479-18-5]; Down 200; 15.8uM; PC3; HT_HG-U133A

CACNB3 MINK1 PLXND1 TAOK2 FZR1 SSH3 KHK PCM1

6.69e-0519615785063_DN
Drugalpha-estradiol; Down 200; 0.01uM; MCF7; HT_HG-U133A

KHNYN ANKRD26 TFAP2A SULF1 PLEKHG3 MACF1 KCTD2 MAP4K4

6.69e-0519615786970_DN
DrugCarbenoxolone disodium salt [7421-40-1]; Down 200; 6.6uM; MCF7; HT_HG-U133A

TTLL5 MINK1 SPTBN2 ANKRD26 TUBGCP5 ZNF10 UTY PCM1

6.69e-0519615783353_DN
DrugViomycin sulfate [37883-00-4]; Down 200; 5.2uM; PC3; HT_HG-U133A

JCAD MINK1 FZR1 LMAN1 LSM14A KHK UTY PCM1

6.69e-0519615787278_DN
DrugSulfathiazole [72-14-0]; Down 200; 15.6uM; PC3; HT_HG-U133A

TTLL5 SPTBN2 EVPL TFAP2A FZR1 PLEKHG3 GSDMD UTY

6.93e-0519715784183_DN
DrugCarteolol hydrochloride [51781-21-6]; Up 200; 12.2uM; MCF7; HT_HG-U133A

CDK20 HIVEP1 MINK1 INO80D STK3 THOP1 SSH3 DZIP3

7.18e-0519815783276_UP
Drug6-Hydroxytropinone [5932-53-6]; Up 200; 25.8uM; HL60; HT_HG-U133A

ASPN TTLL5 TFAP2A FZR1 PLEKHG3 SSH3 EXOC7 HAO2

7.18e-0519815782925_UP
DrugEvoxine [522-11-2]; Down 200; 11.6uM; MCF7; HT_HG-U133A

MARCHF7 TUBGCP5 INO80D PLEKHG3 DZIP3 EXOC7 KDM6A PCM1

7.18e-0519815786041_DN
DrugAmpicillin trihydrate [7177-48-2]; Down 200; 10uM; PC3; HT_HG-U133A

JCAD CACNB3 SETMAR TTLL5 ADAM12 PPL CDADC1 LSM14A

7.18e-0519815786307_DN
DrugRoxarsone [121-19-7]; Down 200; 15.2uM; MCF7; HT_HG-U133A

CACNB3 SETMAR DET1 INO80D CCDC88C FZR1 CEP170B PCM1

7.18e-0519815785470_DN
DrugSulfamerazine [127-79-7]; Down 200; 15.2uM; MCF7; HT_HG-U133A

CDK20 MARCHF7 INO80D STK3 FZR1 SULF1 KCTD2 EXOC7

7.44e-0519915786036_DN
Drug(-)-Adenosine 3',5'-cyclic monophosphate [60-92-4]; Down 200; 12.2uM; MCF7; HT_HG-U133A

TTLL5 MINK1 PLXND1 INO80D CIC FZR1 SSH3 EXOC7

7.44e-0519915783531_DN
DrugBretylium tosylate [61-75-6]; Down 200; 9.6uM; PC3; HT_HG-U133A

ARHGEF28 INO80D CCDC88C FZR1 LMAN1 CATSPER2 ERAP2 PCM1

7.44e-0519915786674_DN
DrugAmiprilose hydrochloride [60414-06-4]; Down 200; 11.8uM; MCF7; HT_HG-U133A

CDK20 MINK1 ZNF10 FZR1 PLEKHG3 SSH3 EXOC7 PCM1

7.44e-0519915784119_DN
DrugNorcyclobenzaprine [303-50-4]; Down 200; 15.4uM; MCF7; HT_HG-U133A

GAK TTLL5 MINK1 SULF1 PLEKHG3 SSH3 DZIP3 UTY

7.44e-0519915782830_DN
DrugDyclonine hydrochloride [536-43-6]; Down 200; 12.2uM; PC3; HT_HG-U133A

TNIK DET1 TTLL5 MINK1 LMAN1 SSH3 KHK EXOC7

7.70e-0520015787261_DN
DiseaseKabuki syndrome (implicated_via_orthology)

KDM6A UTY

7.88e-0531522DOID:0060473 (implicated_via_orthology)
Diseasenetrin-1 measurement

NTN1 PCM1

1.57e-0441522EFO_0022009
Diseasedisease of metabolism (implicated_via_orthology)

YTHDF1 YTHDF2 YTHDF3

1.67e-04211523DOID:0014667 (implicated_via_orthology)
DiseaseHeadache

TUFT1 GPR149 TJP2 MACF1

3.38e-04641524HP_0002315
DiseaseSpinocerebellar Ataxia Type 2

SPTBN2 CIC CCDC88C

7.13e-04341523C0752121
DiseaseSpinocerebellar Ataxia Type 1

SPTBN2 CIC CCDC88C

7.13e-04341523C0752120
DiseaseSpinocerebellar Ataxia Type 5

SPTBN2 CIC CCDC88C

7.13e-04341523C0752123
DiseaseSpinocerebellar Ataxia Type 7

SPTBN2 CIC CCDC88C

7.13e-04341523C0752125
DiseaseSpinocerebellar Ataxia Type 6 (disorder)

SPTBN2 CIC CCDC88C

7.13e-04341523C0752124
DiseaseAtaxia, Spinocerebellar

SPTBN2 CIC CCDC88C

7.13e-04341523C0087012
DiseaseSpinocerebellar Ataxia Type 4

SPTBN2 CIC CCDC88C

7.77e-04351523C0752122
Diseaseobesity (implicated_via_orthology)

ANKRD26 PLXND1 PLXNB2 RSC1A1 STK3 C3

8.95e-042151526DOID:9970 (implicated_via_orthology)
Diseasetetradecanedioate measurement

ANKRD26 MDGA1

9.27e-0491522EFO_0021057
DiseasePulmonary arterial hypertension

VHL BMPR2

1.15e-03101522C2973725
Diseasepolybrominated biphenyl measurement, gestational serum measurement, fetal genotype effect measurement, polybrominated diphenyl ether measurement

PEX5L TRIM5

1.41e-03111522EFO_0007959, EFO_0007961, EFO_0007962, EFO_0007964
Diseaseapolipoprotein A 1 measurement

ARHGEF28 ZNF577 UNC13D TSHR GRM5 TRIM5 TAOK2 FZR1 BMPR2 GPR149 RBM6 MACF1

1.52e-0384815212EFO_0004614
Diseasemosquito bite reaction itch intensity measurement, mosquito bite reaction size measurement

EFCAB6 PCF11 PTPRK SULF1 VANGL1 EXOC1 EXOC7

1.61e-033281527EFO_0008377, EFO_0008378
Diseasedevelopmental disorder of mental health (implicated_via_orthology)

PLXND1 PLXNB2 RASAL3

2.08e-03491523DOID:0060037 (implicated_via_orthology)
Disease2-oxo-hept-3-ene-1,7-dioate hydratase activity

SOX17 BMPR2

2.30e-03141522C1150929
Diseaseindolelactate measurement

SULF1 HAO2

2.30e-03141522EFO_0020012
DiseaseOrofacial cleft

TFAP2A STK3 NTN1

2.33e-03511523HP_0000202
DiseaseIdiopathic pulmonary arterial hypertension

VHL BMPR2

3.02e-03161522C3203102
DiseaseFamilial primary pulmonary hypertension

SOX17 BMPR2

3.41e-03171522C0340543
Diseasecolorectal cancer (is_implicated_in)

BRIP1 YTHDF1 BUB1B KDM6A

3.61e-031211524DOID:9256 (is_implicated_in)
Diseasecleft lip

JCAD ARHGEF28 GRM5 IL22RA2 NTN1 MDGA1

3.63e-032841526EFO_0003959
Diseaseresponse to methotrexate, neurotoxicity

DCT MACF1

4.26e-03191522EFO_0011057, GO_0031427
Diseaseoptic disc size measurement

TSHR LRRIQ1 PLEKHG3 VANGL1 MACF1

4.28e-032051525EFO_0004832

Protein segments in the cluster

PeptideGeneStartEntry
HIQRLQAEEQQKAPG

VANGL1

371

Q8TAA9
QKAEPLERLQSQHRQ

BUB1B

181

O60566
QALHVQSGPEEINKR

ADCY8

656

P40145
ETQQKINHLPAETRQ

BRAP

541

Q7Z569
VVRHAQRPLAQAQVK

CDK20

91

Q8IZL9
QPEIKTIARHLNQEV

COX18

116

Q8N8Q8
SKPHDELLQNNRIQI

ALG1

71

Q9BT22
LKAQHDDQQPVVLRR

ARAP3

1321

Q8WWN8
QHQLVRFSIKPQRIE

CATSPER2

61

Q96P56
SQAQQQLERAKHKPV

CACNB3

46

P54284
KLRTELDKNRHQQAP

CCDC33

826

Q8N5R6
LDKNRHQQAPIILQQ

CCDC33

831

Q8N5R6
EQQRHERSEKKQPQV

ANKRD20A4P

371

Q4UJ75
NPEVRAQNLKEAHRV

ARHGEF5

1571

Q12774
FKPVAQQLLNRIQRH

ARMC2

841

Q8NEN0
QPEHKVLQQLRSRGD

GSDMD

141

P57764
LNRQHSDPNEQVTRK

TFAP2A

321

P05549
QNQELKVRVELLHNP

C3

856

P01024
VTQLNRSHNQQVRPK

COX10

61

Q12887
SKNHPEVLNIRLQRE

ADAM12

61

O43184
INEIHNQSLPQEIAR

CDADC1

306

Q9BWV3
NNQPQVEEERKKHRN

ANKRD26

541

Q9UPS8
PRAQQIEKDIHNVRA

CCDC180

921

Q9P1Z9
LQRQIKRDPQELLHN

CEP170B

386

Q9Y4F5
STIKPRRIQNQNVIH

DET1

6

Q7L5Y6
VRTPEAKENENIHNQ

BIN2

476

Q9UBW5
NLPKNVRVLHLQENN

FLRT2

106

O43155
ANIPRVREIHLENNK

ASPN

286

Q9BXN1
NRIVHSPEVKQQKRL

ASXL3

1886

Q9C0F0
ELEHLQQQRRKSGQP

ANO3

961

Q9BYT9
NRPHRAPITKQNEQE

NTN1

186

O95631
QDRNQALGTHRPVNK

RASAL3

876

Q86YV0
HRPNQDQILTNLSKR

PCOLCE

421

Q15113
HKNDLQDTEISPRQN

RAD18

461

Q9NS91
NNHLTQLPQEVSRLK

LRRC69

116

Q6ZNQ3
PLQDQKSRDADRQHE

ARHGEF28

1421

Q8N1W1
RQLNQHNAVVKAIPV

MDGA1

681

Q8NFP4
DQPNERQVRIQLKDH

MAP4K4

291

O95819
QRLSIHINKKENPNQ

GRM5

931

P41594
APQVLEAQRRHQKEK

MAPKAPK5

191

Q8IW41
KQRPERVSHLLQDNL

ALAS1

176

P13196
EKHNNRNRQTQPELP

EIF1AD

111

Q8N9N8
PNRRQHSKPEKEQIQ

LRRC53

591

A6NM62
QEARSQKPREHENLE

JCAD

121

Q9P266
PQKLQHLEQLRANRN

KDM6A

471

O15550
PRPTNQRINKHVNND

CCDC88C

56

Q9P219
RNRHSAQTEEPVQAK

PCM1

1331

Q15154
VFNQQDKHPARNRTL

PLXNB2

231

O15031
PTARRTQLQHKFEQV

PLXND1

1896

Q9Y4D7
KQVNPSKRLDHLQRA

IGBP1

91

P78318
KVVLQQDPQQAREHA

PPL

1446

O60437
LQRKSRNQQQVPHPA

PEX5L

571

Q8IYB4
QRPKVQLQERVHEIF

EVPL

1186

Q92817
DIRHEVVNINLRNKP

GSTO2

46

Q9H4Y5
EGQNRIHLEIKQLNR

LMAN1

336

P49257
VHKVSRPENEQLRND

LSM14A

241

Q8ND56
EFIIQRNKNVPVNHR

TUBGCP5

491

Q96RT8
HESLKPQRVQFQSRN

IL22RA2

26

Q969J5
EQLRKEQANPHSVSR

DZIP3

686

Q86Y13
IPVHKQTENLQRLQE

EXOC7

61

Q9UPT5
NSLLRNHQNIEPSEK

LRRIQ1

1321

Q96JM4
KRVENLNIHQIFNPE

MACF1

2541

Q9UPN3
VNNNIRKKDHEPLRA

BRIP1

426

Q9BX63
PQRDNRNIFNAIKVE

GPR149

441

Q86SP6
APKQQQHRLSVDANL

PCF11

636

O94913
NNNIDARIPHGLKVQ

PCDHAC2

761

Q9Y5I4
IRNPQQQESLKHATR

BAG2

101

O95816
VRQVIQHDGRNQEKL

FZD6

396

O60353
FHRINENEKSPSQNR

FZR1

61

Q9UM11
HQLQEIAAARNVNPK

GAK

311

O14976
QQLQRDQAHTVTPDK

BICRAL

706

Q6AI39
SFLSPEHQRVQQRKE

GHRL

26

Q9UBU3
HLQKDEQQQPDLSER

EFCAB6

591

Q5THR3
RPKQRSQAVANERAH

GALNT5

226

Q7Z7M9
LGKPENVASQHEQRI

CMYA5

1896

Q8N3K9
QNERNLSHNRRVPKI

BMPR2

526

Q13873
KQRPGEERRLAHQQQ

ECM2

251

O94769
RDENHPNLIRVNATK

GLTP

116

Q9NZD2
QNQQRDHDSKRPKLS

MARCHF7

81

Q9H992
LKLENHQENSRNQKP

LYAR

206

Q9NX58
QLNQNHTLLRPKDRV

ERAP2

646

Q6P179
DNSRKVQHQQQRKPR

INO80D

521

Q53TQ3
QRIDAHNTRQPPEQK

KHK

151

P50053
ENKVREQQPHVERIF

KHNYN

21

O15037
KLVHENPKANEQLNR

ESCO1

106

Q5FWF5
PGHDLLLAVKQQQQR

EXOC1

321

Q9NV70
GIENNVPRHRKNESL

EMB

311

Q6PCB8
LQEQHEKLRQLAKPQ

GOLGA8R

356

I6L899
LELPEERQQNQHKIV

RSC1A1

196

Q92681
KQNPKHQNELRREET

SCNM1

86

Q9BWG6
IARDRQNHQVKPEKR

CENPE

2066

Q02224
RVTVRLNQQQHPDCK

SPOUT1

226

Q5T280
KESITQQEPALRQRH

LIPE

121

Q05469
EDIPVAQTKNINHRR

PTPRK

236

Q15262
IRDNENRTSQGPVKH

KCTD2

171

Q14681
GLVPQRKSRKHENQQ

POTEA

371

Q6S8J7
DQPTERQVRIQLKDH

MINK1

291

Q8N4C8
HPVLQQQRQEELQAR

ALOX15B

131

O15296
TPQKLQHLEQLRANR

UTY

421

O14607
LRANRDNLNPAQKHQ

UTY

431

O14607
RRQFPNKEVLIKHQQ

RBM6

961

P78332
DERKRLAQQNPDLHN

SOX17

81

Q9H6I2
RPNRHLANVTQLVKQ

TRIM27

66

P14373
QQHLQLRLKSPEERA

SYNE2

2646

Q8WXH0
PNHEELQQDKVHRQR

TADA1

311

Q96BN2
RHNKDLVVQTAQPDQ

LINC00869

96

P0C866
RQSEPTKHLLRQLNE

PLEKHG3

446

A1L390
VHPDLQLNKQLIQRV

HAO2

131

Q9NYQ3
IRNIPVINDNVQIKH

SLC9B2

156

Q86UD5
VQEEKQHRIRQLPVG

FTSJ3

706

Q8IY81
PHELTENQKNRRFEV

SETMAR

461

Q53H47
EPVNRIIQKKENNDH

SHOC1

471

Q5VXU9
QELRQKHAAQVRQQP

TAOK2

726

Q9UL54
AQAPDLQRVHKRIQD

NOP2

231

P46087
EVVKSQRPLQRQVHL

OLFML2B

271

Q68BL8
EAQHRARQAEPVQKQ

AARS2

476

Q5JTZ9
QSPQKQEEQRQHLHL

SSH3

86

Q8TE77
RINNNQNKDPILERA

BTG4

61

Q9NY30
QRKPESTHLLENQNT

CLNK

221

Q7Z7G1
RHPNQDNRTVSKILG

CIC

221

Q96RK0
NIRPNRHVANIVEKL

TRIM5

66

Q9C035
SLHRQEIQVVLEKPN

TUFT1

131

Q9NNX1
HQNPRRNFRSLIEEK

ZNF440

56

Q8IYI8
IFVKDVPNNQLRHIR

YTHDF3

506

Q7Z739
LRHIRLENNDNKPVT

YTHDF3

516

Q7Z739
KQQRNEVSFVIHNLP

SEPHS2

331

Q99611
KNPEQRATATQLLQH

STK3

261

Q13188
DQPNERQVRIQLKDH

TNIK

291

Q9UKE5
VSLQHQRQEQRPVEK

TNIK

501

Q9UKE5
QEAQNARIEIAQKHP

TJP2

1101

Q9UDY2
QHNQLRVKRSPGLQD

RBP3

1231

P10745
RQALARVQHKQQQLP

SPTBN2

1811

O15020
RNLHQEKVVPQQSLV

PROM2

666

Q8N271
THNIREEKINNSQPA

SAGE1

626

Q9NXZ1
ELVNDHARKNRINPL

SPANXD

66

Q9BXN6
KARNQHLVSQQKDPD

TPR

1336

P12270
DNQERKTELPREHAN

SPARCL1

216

Q14515
KEHSERQPLNRNSLR

TP53INP1

196

Q96A56
AQLIQHQRTERGEKP

ZNF577

171

Q9BSK1
FPNEEDRKHQQRSII

POLK

516

Q9UBT6
HPNVQKDLERLTQER

VHL

191

P40337
NPKRREEVNRLHQQL

SMCO3

11

A2RU48
QQQQKEQRSLAAHPR

TCF20

1771

Q9UGU0
IRQNIHSLSPQEREQ

DCT

126

P40126
VKNLHQRLEGQRPEN

PTPN6

256

P29350
ENPERHLRQVAFTQK

ZNF10

141

P21506
NIIHQRKSDFPLRQN

ZNF613

111

Q6PF04
PRKQVQQNVHNPIRT

ZNF792

176

Q3KQV3
RDPNNQLHVIKNLKI

TRAPPC8

56

Q9Y2L5
RNGLHLPRETQENIK

THOP1

151

P52888
QVLQPRNIAKRHDEG

SULF1

566

Q8IWU6
QGIRPHDIFRQRKQN

VIRMA

1631

Q69YN4
HQQTLQRVRELEKPI

UNC13D

96

Q70J99
QIHPRNLRDKIEEAQ

HIVEP1

6

P15822
PNHEQVLRRATSQKA

TTLL5

1231

Q6EMB2
RHIRLENNENKPVTN

YTHDF2

511

Q9Y5A9
VKDVPNNQLRHIRLE

YTHDF1

481

Q9BYJ9
HIRLENNDNKPVTNS

YTHDF1

491

Q9BYJ9
NENHPRLNQSQEIMR

ATP6V0A2

431

Q9Y487
QRKSVNALNSPLHQE

TSHR

311

P16473
DHLQQPLQNQKILKR

ZNF649

86

Q9BS31
ERNFPHKTVAAQRQR

GARIN5B

201

Q8N5Q1
PDKLRQKLQTNAHNR

LRRC8C

411

Q8TDW0
IEEQTSQLRQNHIKP

NECAB2

191

Q7Z6G3