Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	transmembrane signaling receptor activity	OR8H2 MAS1 ADGRV1 IL22RA1 PROKR1 TAS2R4 ADRB1 ADRB2 PTPRB PTPRF PROKR2 PTPRK PTPRZ1 PLXNA1 ADGRL3 GPR6 DRD5 OR5AU1 GPR34 OR8K5 ABCC9 SUCNR1 PKD1L3 MST1R IGF2R P2RY1 MTNR1B SORCS3 HRH4 RXFP4	9.97e-06	1353	188	30	GO:0004888
GeneOntologyMolecularFunction	transmembrane receptor protein tyrosine phosphatase activity	PTPRB PTPRF PTPRK PTPRZ1	1.65e-05	17	188	4	GO:0005001
GeneOntologyMolecularFunction	transmembrane receptor protein phosphatase activity	PTPRB PTPRF PTPRK PTPRZ1	1.65e-05	17	188	4	GO:0019198
GeneOntologyMolecularFunction	ATPase-coupled inorganic anion transmembrane transporter activity	ABCC3 ABCC1 ABCC9	9.39e-05	10	188	3	GO:0043225
GeneOntologyMolecularFunction	G protein-coupled receptor activity	OR8H2 MAS1 ADGRV1 PROKR1 TAS2R4 ADRB1 ADRB2 PROKR2 ADGRL3 GPR6 DRD5 OR5AU1 GPR34 OR8K5 SUCNR1 P2RY1 MTNR1B SORCS3 HRH4 RXFP4	2.64e-04	884	188	20	GO:0004930
GeneOntologyMolecularFunction	guanyl-nucleotide exchange factor activity	DOCK11 OBSCN LAMTOR1 RGL2 RIC1 ARHGEF19 PLEKHG2 SBF2 PLCE1	3.53e-04	231	188	9	GO:0005085
GeneOntologyMolecularFunction	beta-adrenergic receptor activity	ADRB1 ADRB2	5.23e-04	4	188	2	GO:0004939
GeneOntologyBiologicalProcess	positive regulation of blood pressure by epinephrine-norepinephrine	ADRB1 ADRB2 DRD5	2.58e-05	7	189	3	GO:0003321
GeneOntologyBiologicalProcess	Rab protein signal transduction	RAB4B RAB30 RAB4A RAB12	3.62e-05	21	189	4	GO:0032482
GeneOntologyBiologicalProcess	regulation of systemic arterial blood pressure by norepinephrine-epinephrine	ADRB1 ADRB2 DRD5	4.10e-05	8	189	3	GO:0001993
GeneOntologyBiologicalProcess	modified amino acid transport	SLC22A15 ABCC1 SLC7A6 SLC1A4 LRP2	4.98e-05	44	189	5	GO:0072337
GeneOntologyCellularComponent	axon	LDLRAP1 EPS8 SETX NEK3 ADRB2 KIF3B PTPRF PTPRK CLU PTPRZ1 ADGRL3 ROGDI DRD5 ARHGAP4 ELFN1 TNN SBF2 LRP2 SLC38A7 UNC13C CDH1 UNC13A	2.70e-05	891	193	22	GO:0030424
GeneOntologyCellularComponent	cluster of actin-based cell projections	EPS8 CDHR2 SLC28A3 ADGRV1 PROM1 MYO15B DRD5 MYO1B PKHD1L1 LRP2	4.45e-05	223	193	10	GO:0098862
GeneOntologyCellularComponent	brush border	EPS8 CDHR2 SLC28A3 PROM1 MYO15B DRD5 MYO1B LRP2	8.62e-05	152	193	8	GO:0005903
GeneOntologyCellularComponent	cell surface	IQGAP2 MAS1 ADGRV1 PHB1 PROM1 MELTF PTPRK CLU KCNJ5 C3 RC3H2 HBEGF SUCNR1 PKD1L3 SLC1A4 MST1R IGF2R P2RY1 IGHG1 TNN LRP2 TNR CDH1	2.49e-04	1111	193	23	GO:0009986
GeneOntologyCellularComponent	tenascin complex	TNN TNR	5.03e-04	4	193	2	GO:0090733
Domain	PTPc	PTPN1 PTPRB PTPRF PTPRK PTPRZ1	2.87e-05	36	188	5	SM00194
Domain	FN3	OBSCN IL22RA1 PTPRB PTPRF PTPRK PTPRZ1 HCFC2 COL7A1 TNN TNR	3.47e-05	199	188	10	PS50853
Domain	fn3	OBSCN PTPRB PTPRF PTPRK PTPRZ1 HCFC2 COL7A1 TNN TNR	3.94e-05	162	188	9	PF00041
Domain	TYR_PHOSPHATASE_PTP	PTPN1 PTPRB PTPRF PTPRK PTPRZ1	4.27e-05	39	188	5	PS50055
Domain	FN3_dom	OBSCN IL22RA1 PTPRB PTPRF PTPRK PTPRZ1 HCFC2 COL7A1 TNN TNR	5.25e-05	209	188	10	IPR003961
Domain	PTPase_domain	PTPN1 PTPRB PTPRF PTPRK PTPRZ1	5.47e-05	41	188	5	IPR000242
Domain	Y_phosphatase	PTPN1 PTPRB PTPRF PTPRK PTPRZ1	5.47e-05	41	188	5	PF00102
Domain	Ig_E-set	F13A1 KCNJ5 A2ML1 PLXNA1 PKHD1L1 MST1R SNRNP200	8.74e-05	104	188	7	IPR014756
Domain	FN3	OBSCN PTPRB PTPRF PTPRK PTPRZ1 HCFC2 COL7A1 TNN TNR	1.10e-04	185	188	9	SM00060
Domain	Unc-13	UNC13C UNC13A	3.00e-04	3	188	2	IPR027080
Domain	GPR137	GPR137C GPR137B	3.00e-04	3	188	2	IPR029723
Domain	PTPc_motif	PTPN1 PTPRB PTPRF PTPRK PTPRZ1	3.16e-04	59	188	5	SM00404
Domain	Tyr_Pase_cat	PTPN1 PTPRB PTPRF PTPRK PTPRZ1	3.16e-04	59	188	5	IPR003595
Domain	P-loop_NTPase	RAB19 ABCC3 ERCC2 SETX ABCA13 MCM3 MYO15B TRANK1 KIF3B RAB4B RAB30 RAB4A NLRP13 RAB12 ABCC1 NWD1 ABCC9 MYO1B ARHGAP5 SNRNP200	3.63e-04	848	188	20	IPR027417
Domain	GPS	ADGRV1 PKDREJ ADGRL3 PKD1L3	3.64e-04	34	188	4	SM00303
Domain	Prot-tyrosine_phosphatase-like	PTPN1 PTPRB PTPRF PTPRK PTPRZ1 SBF2	4.96e-04	99	188	6	IPR029021
Domain	GPS	ADGRV1 PKDREJ ADGRL3 PKD1L3	5.06e-04	37	188	4	IPR000203
Domain	Multidrug-R_assoc	ABCC3 ABCC1	5.97e-04	4	188	2	IPR005292
Domain	Cadherin_CS	CDHR2 FAT4 PCDHGA7 FAT3 CDH1 CDH18	8.25e-04	109	188	6	IPR020894
Domain	Tyr_Pase_AS	PTPN1 PTPRB PTPRF PTPRK PTPRZ1	8.46e-04	73	188	5	IPR016130
Domain	RAB	RAB19 RAB4B RAB30 RAB4A RAB12	8.46e-04	73	188	5	PS51419
Domain	Munc13_dom-2	UNC13C UNC13A	9.88e-04	5	188	2	IPR014772
Domain	MHD2	UNC13C UNC13A	9.88e-04	5	188	2	PS51259
Domain	Munc13_subgr_dom-2	UNC13C UNC13A	9.88e-04	5	188	2	IPR019558
Domain	Membr_traf_MHD	UNC13C UNC13A	9.88e-04	5	188	2	PF10540
Domain	DUF1041	UNC13C UNC13A	9.88e-04	5	188	2	SM01145
Domain	CADHERIN_1	CDHR2 FAT4 PCDHGA7 FAT3 CDH1 CDH18	9.95e-04	113	188	6	PS00232
Domain	Cadherin	CDHR2 FAT4 PCDHGA7 FAT3 CDH1 CDH18	9.95e-04	113	188	6	PF00028
Domain	CADHERIN_2	CDHR2 FAT4 PCDHGA7 FAT3 CDH1 CDH18	1.04e-03	114	188	6	PS50268
Domain	-	CDHR2 FAT4 PCDHGA7 FAT3 CDH1 CDH18	1.04e-03	114	188	6	2.60.40.60
Domain	CA	CDHR2 FAT4 PCDHGA7 FAT3 CDH1 CDH18	1.09e-03	115	188	6	SM00112
Domain	Cadherin-like	CDHR2 FAT4 PCDHGA7 FAT3 CDH1 CDH18	1.14e-03	116	188	6	IPR015919
Domain	Cadherin	CDHR2 FAT4 PCDHGA7 FAT3 CDH1 CDH18	1.25e-03	118	188	6	IPR002126
Domain	GPCR_Rhodpsn_7TM	OR8H2 MAS1 PROKR1 ADRB1 ADRB2 PROKR2 GPR6 DRD5 OR5AU1 GPR34 OR8K5 SUCNR1 P2RY1 MTNR1B HRH4 RXFP4	1.25e-03	670	188	16	IPR017452
Domain	ABC_tran	ABCC3 ABCA13 ABCC1 ABCC9	1.37e-03	48	188	4	PF00005
Domain	-	KBTBD8 KLHL42 HCFC2 KLHL14	1.37e-03	48	188	4	2.120.10.80
Domain	ABC_TRANSPORTER_2	ABCC3 ABCA13 ABCC1 ABCC9	1.37e-03	48	188	4	PS50893
Domain	7tm_1	OR8H2 MAS1 PROKR1 ADRB1 ADRB2 PROKR2 GPR6 DRD5 OR5AU1 GPR34 OR8K5 SUCNR1 P2RY1 MTNR1B HRH4 RXFP4	1.39e-03	677	188	16	PF00001
Domain	-	RAB19 ABCC3 ERCC2 SETX ABCA13 MCM3 TRANK1 RAB4B RAB30 RAB4A NLRP13 RAB12 ABCC1 NWD1 ABCC9 ARHGAP5 SNRNP200	1.47e-03	746	188	17	3.40.50.300
Domain	ABC_TRANSPORTER_1	ABCC3 ABCA13 ABCC1 ABCC9	1.48e-03	49	188	4	PS00211
Domain	G_PROTEIN_RECEP_F1_1	OR8H2 MAS1 PROKR1 ADRB1 ADRB2 PROKR2 GPR6 DRD5 OR5AU1 GPR34 OR8K5 SUCNR1 P2RY1 MTNR1B HRH4 RXFP4	1.57e-03	685	188	16	PS00237
Domain	ABC_transporter-like	ABCC3 ABCA13 ABCC1 ABCC9	1.60e-03	50	188	4	IPR003439
Domain	G_PROTEIN_RECEP_F1_2	OR8H2 MAS1 PROKR1 ADRB1 ADRB2 PROKR2 GPR6 DRD5 OR5AU1 GPR34 OR8K5 SUCNR1 P2RY1 MTNR1B HRH4 RXFP4	1.72e-03	691	188	16	PS50262
Domain	ABC_membrane	ABCC3 ABCC1 ABCC9	1.74e-03	24	188	3	PF00664
Domain	GPCR_Rhodpsn	OR8H2 MAS1 PROKR1 ADRB1 ADRB2 PROKR2 GPR6 DRD5 OR5AU1 GPR34 OR8K5 SUCNR1 P2RY1 MTNR1B HRH4 RXFP4	1.74e-03	692	188	16	IPR000276
Domain	TYR_PHOSPHATASE_1	PTPN1 PTPRB PTPRF PTPRK PTPRZ1	1.77e-03	86	188	5	PS00383
Domain	TYR_PHOSPHATASE_dom	PTPN1 PTPRB PTPRF PTPRK PTPRZ1	1.86e-03	87	188	5	IPR000387
Domain	TYR_PHOSPHATASE_2	PTPN1 PTPRB PTPRF PTPRK PTPRZ1	1.86e-03	87	188	5	PS50056
Domain	Munc13_1	UNC13C UNC13A	2.05e-03	7	188	2	IPR014770
Domain	TLV_coat	ERVV-1 ERVV-2	2.05e-03	7	188	2	PF00429
Domain	MHD1	UNC13C UNC13A	2.05e-03	7	188	2	PS51258
Domain	DUF1041	UNC13C UNC13A	2.05e-03	7	188	2	PF06292
Domain	CAPS_dom	UNC13C UNC13A	2.05e-03	7	188	2	IPR010439
Domain	Kelch-typ_b-propeller	KBTBD8 KLHL42 HCFC2 KLHL14	2.27e-03	55	188	4	IPR015915
Domain	-	PTPN1 PTPRB PTPRF PTPRK PTPRZ1	2.38e-03	92	188	5	3.90.190.10
Domain	IPT	PLXNA1 PKHD1L1 MST1R	2.46e-03	27	188	3	SM00429
Domain	Ras	RAB19 RAB4B RAB30 RAB4A RAB12 ARHGAP5	2.56e-03	136	188	6	PF00071
Domain	MacrogloblnA2_thiol-ester-bond	A2ML1 C3	2.71e-03	8	188	2	IPR019565
Domain	TLV/ENV_coat_polyprotein	ERVV-1 ERVV-2	2.71e-03	8	188	2	IPR018154
Domain	Thiol-ester_cl	A2ML1 C3	2.71e-03	8	188	2	PF10569
Domain	MacrogloblnA2_CS	A2ML1 C3	2.71e-03	8	188	2	IPR019742
Domain	A2M_N_2	A2ML1 C3	2.71e-03	8	188	2	SM01359
Domain	-	A2ML1 C3	2.71e-03	8	188	2	2.60.40.690
Domain	A2M_recep	A2ML1 C3	2.71e-03	8	188	2	SM01361
Domain	A2M	A2ML1 C3	2.71e-03	8	188	2	SM01360
Domain	ABC_TM1F	ABCC3 ABCC1 ABCC9	2.73e-03	28	188	3	PS50929
Domain	ABC1_TM_dom	ABCC3 ABCC1 ABCC9	2.73e-03	28	188	3	IPR011527
Pathway	REACTOME_TRANSPORT_OF_RCBL_WITHIN_THE_BODY	LDLRAP1 ABCC1 TCN1 LRP2	8.12e-07	8	149	4	M45025
Pathway	WP_GPCRS_NONODORANT	MAS1 PROKR1 TAS2R4 ADRB1 ADRB2 PROKR2 ADGRL3 GPR6 DRD5 SUCNR1 P2RY1 MTNR1B HRH4 RXFP4	8.64e-07	266	149	14	MM15843
Pathway	REACTOME_TRANSPORT_OF_RCBL_WITHIN_THE_BODY	LDLRAP1 ABCC1 LRP2	3.93e-05	7	149	3	MM15703
Pathway	REACTOME_COBALAMIN_CBL_VITAMIN_B12_TRANSPORT_AND_METABOLISM	LDLRAP1 ABCC1 TCN1 LRP2	7.56e-05	22	149	4	M27084
Pubmed	Large-scale proteomics and phosphoproteomics of urinary exosomes.	RAB19 RIDA EPS8 IQGAP2 CDHR2 ACP2 ADGRV1 PROM1 MELTF FCGBP KIF3B SMPDL3B MVB12A CLU HPD UPK3A LAMTOR1 MYO1B SUCNR1 PKD1L3 IGF2R LRP2	6.07e-08	1016	193	22	19056867
Pubmed	Redundant catecholamine signaling consolidates fear memory via phospholipase C.	ADRB1 ADRB2 DRD5	1.67e-06	5	193	3	22323706
Pubmed	β-arrestin-biased agonism of β-adrenergic receptor regulates Dicer-mediated microRNA maturation to promote cardioprotective signaling.	ADRB1 ADRB2 GRK6	3.32e-06	6	193	3	29627294
Pubmed	Expression of protein tyrosine phosphatase genes in the developing brain of mouse and rat.	PTPN1 PTPRB PTPRF	5.79e-06	7	193	3	7804149
Pubmed	In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.	EPS8 CDHR2 ACP2 PROM1 MELTF FCGBP SMPDL3B MVB12A CLU C3 UPK3A DNASE1 FAT4 CPNE9 MAN1C1 IGF2R IGHG1 LRP2 CDH1	9.07e-06	1070	193	19	23533145
Pubmed	HIV-1 Tat C phosphorylates VE-cadherin complex and increases human brain microvascular endothelial cell permeability.	PTPRB NOX4 CDH1	9.23e-06	8	193	3	24965120
Pubmed	Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.	RIDA SLC28A3 ADGRV1 MRPS22 RYR2 HPD NOX4 ABCC9 MYO1B PKHD1L1 FICD TSBP1 FAM180A MTNR1B GREB1 UNC13A	1.40e-05	814	193	16	23251661
Pubmed	Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.	F13A1 FCGBP PTPRF CLU PTPRZ1 C3 CPNE9 TCN1 TNN	1.49e-05	257	193	9	16335952
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	SETX DOCK11 OBSCN SLC28A3 MYO15B FAT4 APPBP2 UBR4 ARHGAP5 ZBTB44 PDE12 LRP2 PRKDC TNR SNRNP200	1.73e-05	736	193	15	29676528
Pubmed	Slac2-a/melanophilin, the missing link between Rab27 and myosin Va: implications of a tripartite protein complex for melanosome transport.	RAB19 RAB4B RAB30 RAB4A RAB12	1.80e-05	58	193	5	11856727
Pubmed	The Slp homology domain of synaptotagmin-like proteins 1-4 and Slac2 functions as a novel Rab27A binding domain.	RAB19 RAB4B RAB30 RAB4A RAB12	2.50e-05	62	193	5	11773082
Pubmed	A novel receptor-type protein tyrosine phosphatase with a single catalytic domain is specifically expressed in mouse brain.	PTPN1 PTPRB PTPRF	2.69e-05	11	193	3	7832766
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	MORN1 VPS45 OBSCN PAQR5 EVC ADGRV1 PTPRB SMPDL3B TECPR2 TXNL4B MAD1L1 CYB5D1 RIC1 CUL4A MAN1C1 PELI2 SLC35A3 GPR137C SBF2 GPR137B SLC35F2 GREB1	3.02e-05	1489	193	22	28611215
Pubmed	β-Adrenergic receptor-PI3K signaling crosstalk in mouse heart: elucidation of immediate downstream signaling cascades.	ADRB1 ADRB2	3.06e-05	2	193	2	22028912
Pubmed	Beta1- and beta2-adrenergic receptor polymorphisms affect susceptibility to idiopathic dilated cardiomyopathy.	ADRB1 ADRB2	3.06e-05	2	193	2	17667029
Pubmed	Enriched environment enhances β-adrenergic signaling to prevent microglia inflammation by amyloid-β.	ADRB1 ADRB2	3.06e-05	2	193	2	30093491
Pubmed	Anti-β-adrenoceptors autoimmunity causing 'idiopathic' arrhythmias and cardiomyopathy.	ADRB1 ADRB2	3.06e-05	2	193	2	22447021
Pubmed	Carvedilol inhibits EGF-mediated JB6 P+ colony formation through a mechanism independent of adrenoceptors.	ADRB1 ADRB2	3.06e-05	2	193	2	31107911
Pubmed	cAMP-mediated beta-adrenergic signaling negatively regulates Gq-coupled receptor-mediated fetal gene response in cardiomyocytes.	ADRB1 ADRB2	3.06e-05	2	193	2	18851973
Pubmed	Persistence of circadian variation in arterial blood pressure in beta1/beta2-adrenergic receptor-deficient mice.	ADRB1 ADRB2	3.06e-05	2	193	2	18305025
Pubmed	Crystal structures of Nova-1 and Nova-2 K-homology RNA-binding domains.	NOVA1 NOVA2	3.06e-05	2	193	2	10368286
Pubmed	Functional β-adrenoceptors are important for early muscle regeneration in mice through effects on myoblast proliferation and differentiation.	ADRB1 ADRB2	3.06e-05	2	193	2	25000590
Pubmed	Cardiac β2-Adrenergic Receptor Phosphorylation at Ser355/356 Regulates Receptor Internalization and Functional Resensitization.	ADRB1 ADRB2	3.06e-05	2	193	2	27541735
Pubmed	Cardiac pressure overload hypertrophy is differentially regulated by β-adrenergic receptor subtypes.	ADRB1 ADRB2	3.06e-05	2	193	2	21705675
Pubmed	Targeted disruption of the mouse beta1-adrenergic receptor gene: developmental and cardiovascular effects.	ADRB1 ADRB2	3.06e-05	2	193	2	8693001
Pubmed	Genetic polymorphisms in ADRB2 and ADRB1 are associated with differential survival in heart failure patients taking β-blockers.	ADRB1 ADRB2	3.06e-05	2	193	2	34642472
Pubmed	Epithelial protein-tyrosine phosphatase 1B contributes to the induction of mammary tumors by HER2/Neu but is not essential for tumor maintenance.	PTPN1 PRKDC	3.06e-05	2	193	2	21849469
Pubmed	Role of Oxidative Stress in Prognosis of Ovarian Cancer.	PHB1 NOX4	3.06e-05	2	193	2	33548975
Pubmed	Clustering heart rate dynamics is associated with β-adrenergic receptor polymorphisms: analysis by information-based similarity index.	ADRB1 ADRB2	3.06e-05	2	193	2	21573230
Pubmed	β1-adrenergic receptor stimulation by agonist Compound 49b restores insulin receptor signal transduction in vivo.	ADRB1 ADRB2	3.06e-05	2	193	2	24966659
Pubmed	Gene conversion and purifying selection of a placenta-specific ERV-V envelope gene during simian evolution.	ERVV-1 ERVV-2	3.06e-05	2	193	2	18826608
Pubmed	Polymorphisms of the beta-1 and beta-2 adrenergic receptors in Polish patients with idiopathic dilated cardiomyopathy.	ADRB1 ADRB2	3.06e-05	2	193	2	19378229
Pubmed	Beta1- and Beta2-Adrenoceptors Expression Patterns in Human Non-small Cell Lung Cancer: Relationship with Cancer Histology.	ADRB1 ADRB2	3.06e-05	2	193	2	31620969
Pubmed	The Arg16Gly-β(2)-adrenoceptor single nucleotide polymorphism: exercise capacity and survival in patients with end-stage heart failure.	ADRB1 ADRB2	3.06e-05	2	193	2	20803192
Pubmed	Genetic mapping of adrenergic receptor genes in humans.	ADRB1 ADRB2	3.06e-05	2	193	2	7583452
Pubmed	Beta-adrenergic receptor gene polymorphisms and cardiovascular reactivity to stress in Black adolescents and young adults.	ADRB1 ADRB2	3.06e-05	2	193	2	20374546
Pubmed	Association between beta-1 and beta-2 adrenergic receptor gene polymorphisms and the response to beta-blockade in patients with stable congestive heart failure.	ADRB1 ADRB2	3.06e-05	2	193	2	15861037
Pubmed	Transient tachypnea of the newborn (TTN): a role for polymorphisms in the beta-adrenergic receptor (ADRB) encoding genes?	ADRB1 ADRB2	3.06e-05	2	193	2	18540901
Pubmed	Parental imprinting of the Mas protooncogene in mouse.	MAS1 IGF2R	3.06e-05	2	193	2	7894489
Pubmed	Tubular up-regulation of clusterin mRNA in murine lupus-like nephritis.	CLU LRP2	3.06e-05	2	193	2	9546356
Pubmed	Inhibition of ron kinase blocks conversion of micrometastases to overt metastases by boosting antitumor immunity.	MST1R PRKDC	3.06e-05	2	193	2	23612011
Pubmed	Modeling of human prokineticin receptors: interactions with novel small-molecule binders and potential off-target drugs.	PROKR1 PROKR2	3.06e-05	2	193	2	22132188
Pubmed	Beta2-adrenergic receptor genotype and survival among patients receiving beta-blocker therapy after an acute coronary syndrome.	ADRB1 ADRB2	3.06e-05	2	193	2	16189366
Pubmed	Polymorphisms in beta-adrenergic receptor genes in the acquired long QT syndrome.	ADRB1 ADRB2	3.06e-05	2	193	2	11942593
Pubmed	Frequency of compound genotypes associated with beta-blocker efficacy in congestive heart failure.	ADRB1 ADRB2	3.06e-05	2	193	2	15212591
Pubmed	β2-Adrenergic Receptor Gene Polymorphisms Are Associated with Cardiovascular Events But not All-Cause Mortality in Coronary Artery Disease Patients: A Meta-Analysis of Prospective Studies.	ADRB1 ADRB2	3.06e-05	2	193	2	30668166
Pubmed	Prokineticin receptor variants (PKR1-I379V and PKR2-V331M) are protective genotypes in human early pregnancy.	PROKR1 PROKR2	3.06e-05	2	193	2	23687280
Pubmed	Association of beta-1 and beta-2 adrenergic receptor gene polymorphisms with myocardial infarction.	ADRB1 ADRB2	3.06e-05	2	193	2	19623647
Pubmed	Regulation of renin secretion and expression in mice deficient in beta1- and beta2-adrenergic receptors.	ADRB1 ADRB2	3.06e-05	2	193	2	17515456
Pubmed	Differential distribution of beta-adrenergic receptor subtypes in blood vessels of knockout mice lacking beta(1)- or beta(2)-adrenergic receptors.	ADRB1 ADRB2	3.06e-05	2	193	2	11641423
Pubmed	Differential evolutionary fate of an ancestral primate endogenous retrovirus envelope gene, the EnvV syncytin, captured for a function in placentation.	ERVV-1 ERVV-2	3.06e-05	2	193	2	23555306
Pubmed	Quantitative assessment of beta 1- and beta 2-adrenergic receptor homo- and heterodimerization by bioluminescence resonance energy transfer.	ADRB1 ADRB2	3.06e-05	2	193	2	12244098
Pubmed	Beta1-adrenergic receptors stimulate cardiac contractility and CaMKII activation in vivo and enhance cardiac dysfunction following myocardial infarction.	ADRB1 ADRB2	3.06e-05	2	193	2	19633206
Pubmed	Role of beta1- and beta2-adrenoceptor polymorphisms in heart failure: a case-control study.	ADRB1 ADRB2	3.06e-05	2	193	2	15342173
Pubmed	Beta-adrenergic receptor gene polymorphisms and hemodynamic response to dobutamine during dobutamine stress echocardiography.	ADRB1 ADRB2	3.06e-05	2	193	2	18253135
Pubmed	Analysis of beta1 and beta2-adrenergic receptors polymorphism in patients with apical ballooning cardiomyopathy.	ADRB1 ADRB2	3.06e-05	2	193	2	22299391
Pubmed	A physical/psychological and biological stress combine to enhance endoplasmic reticulum stress.	ADRB1 ADRB2	3.06e-05	2	193	2	26391182
Pubmed	Effects of milrinone on contractility and cyclic adenosine monophosphate production induced by beta1- and beta2-adrenergic receptor activation in human myocardium.	ADRB1 ADRB2	3.06e-05	2	193	2	17919552
Pubmed	Deletion of β-adrenergic receptor 1, 2, or both leads to different bone phenotypes and response to mechanical stimulation.	ADRB1 ADRB2	3.06e-05	2	193	2	22407956
Pubmed	Differential cardioprotective/cardiotoxic effects mediated by beta-adrenergic receptor subtypes.	ADRB1 ADRB2	3.06e-05	2	193	2	16040722
Pubmed	Clusterin and LRP2 are critical components of the hypothalamic feeding regulatory pathway.	CLU LRP2	3.06e-05	2	193	2	23673647
Pubmed	Association of beta-adrenoceptor polymorphisms with cardiac autonomic modulation in Japanese males.	ADRB1 ADRB2	3.06e-05	2	193	2	17893006
Pubmed	Polymorphisms of the beta adrenergic receptor predict left ventricular remodeling following acute myocardial infarction.	ADRB1 ADRB2	3.06e-05	2	193	2	21626217
Pubmed	β-1 and β-2 adrenergic receptor polymorphism and association with cardiovascular response to orthostatic screening.	ADRB1 ADRB2	3.06e-05	2	193	2	21807569
Pubmed	Distinct interactions of human beta1- and beta2-adrenoceptors with isoproterenol, epinephrine, norepinephrine, and dopamine.	ADRB1 ADRB2	3.06e-05	2	193	2	18772317
Pubmed	Beta 1/beta 2-adrenergic receptor heterodimerization regulates beta 2-adrenergic receptor internalization and ERK signaling efficacy.	ADRB1 ADRB2	3.06e-05	2	193	2	12140284
Pubmed	Quantitative Analysis of the Cardiac Phosphoproteome in Response to Acute β-Adrenergic Receptor Stimulation In Vivo.	ADRB1 ADRB2	3.06e-05	2	193	2	34830474
Pubmed	Common genetic variation of beta1- and beta2-adrenergic receptor and response to four classes of antihypertensive treatment.	ADRB1 ADRB2	3.06e-05	2	193	2	20300048
Pubmed	Upregulation of alveolar epithelial active Na+ transport is dependent on beta2-adrenergic receptor signaling.	ADRB1 ADRB2	3.06e-05	2	193	2	15016730
Pubmed	[Interactions between beta1 and beta2 adrenergic receptor polymorphisms as risk factors for chronic heart failure].	ADRB1 ADRB2	3.06e-05	2	193	2	19301767
Pubmed	Integrative modeling defines the Nova splicing-regulatory network and its combinatorial controls.	NOVA1 NOVA2	3.06e-05	2	193	2	20558669
Pubmed	Transferability of thermostabilizing mutations between beta-adrenergic receptors.	ADRB1 ADRB2	3.06e-05	2	193	2	19883298
Pubmed	Differences in endosomal targeting of human (beta)1- and (beta)2-adrenergic receptors following clathrin-mediated endocytosis.	ADRB1 ADRB2	3.06e-05	2	193	2	14734649
Pubmed	An RNA map predicting Nova-dependent splicing regulation.	NOVA1 NOVA2	3.06e-05	2	193	2	17065982
Pubmed	Gαi is required for carvedilol-induced β1 adrenergic receptor β-arrestin biased signaling.	ADRB1 ADRB2	3.06e-05	2	193	2	29167435
Pubmed	Differential cardiotoxic/cardioprotective effects of beta-adrenergic receptor subtypes in myocytes and fibroblasts in doxorubicin cardiomyopathy.	ADRB1 ADRB2	3.06e-05	2	193	2	16458323
Pubmed	CLIP identifies Nova-regulated RNA networks in the brain.	NOVA1 NOVA2	3.06e-05	2	193	2	14615540
Pubmed	Vitamin B12 transport from food to the body's cells--a sophisticated, multistep pathway.	ABCC1 TCN1	3.06e-05	2	193	2	22547309
Pubmed	The 15-amino acid motif of the C terminus of the beta2-adrenergic receptor is sufficient to confer insulin-stimulated counterregulation to the beta1-adrenergic receptor.	ADRB1 ADRB2	3.06e-05	2	193	2	15388645
Pubmed	beta-adrenergic receptor gene polymorphisms and beta-blocker treatment outcomes in hypertension.	ADRB1 ADRB2	3.06e-05	2	193	2	18615004
Pubmed	Beta-adrenergic receptors gene polymorphisms are associated with cardiac contractility and blood pressure variability.	ADRB1 ADRB2	3.06e-05	2	193	2	35099251
Pubmed	Cardiomyocyte sulfonylurea receptor 2-KATP channel mediates cardioprotection and ST segment elevation.	KCNJ5 ABCC9	3.06e-05	2	193	2	20656890
Pubmed	Beta-adrenergic receptor polymorphisms and cardiac graft function in potential organ donors.	ADRB1 ADRB2	3.06e-05	2	193	2	22994654
Pubmed	Confinement of β(1)- and β(2)-adrenergic receptors in the plasma membrane of cardiomyocyte-like H9c2 cells is mediated by selective interactions with PDZ domain and A-kinase anchoring proteins but not caveolae.	ADRB1 ADRB2	3.06e-05	2	193	2	21680711
Pubmed	Chronic stress promotes gastric cancer progression via the adrenoceptor beta 2/PlexinA1 pathway.	ADRB2 PLXNA1	3.06e-05	2	193	2	38331165
Pubmed	Arrhythmogenic remodeling of β2 versus β1 adrenergic signaling in the human failing heart.	ADRB1 ADRB2	3.06e-05	2	193	2	25673629
Pubmed	Association of β-adrenergic receptor genes polymorphisms with incidence of subsequent cardiovascular events in Han Chinese patients with coronary artery disease.	ADRB1 ADRB2	3.06e-05	2	193	2	24342311
Pubmed	Transient {beta}2-adrenoceptor activation confers pregnancy loss by disrupting embryo spacing at implantation.	ADRB1 ADRB2	3.06e-05	2	193	2	21148315
Pubmed	Adrenergic receptor gene polymorphism and left ventricular reverse remodelling after cardiac resynchronization therapy: preliminary results.	ADRB1 ADRB2	3.06e-05	2	193	2	23729404
Pubmed	Common beta-adrenergic receptor polymorphisms are not associated with risk of sudden cardiac death in patients with coronary artery disease.	ADRB1 ADRB2	3.06e-05	2	193	2	18534365
Pubmed	The neuronal RNA-binding protein Nova-2 is implicated as the autoantigen targeted in POMA patients with dementia.	NOVA1 NOVA2	3.06e-05	2	193	2	9789075
Pubmed	β-adrenoceptors are upregulated in human melanoma and their activation releases pro-tumorigenic cytokines and metalloproteases in melanoma cell lines.	ADRB1 ADRB2	3.06e-05	2	193	2	23318885
Pubmed	β-adrenergic receptor mediation of stress-induced reinstatement of extinguished cocaine-induced conditioned place preference in mice: roles for β1 and β2 adrenergic receptors.	ADRB1 ADRB2	3.06e-05	2	193	2	22593095
Pubmed	Expression of prokineticin receptors in mouse cultured astrocytes and involvement in cell proliferation.	PROKR1 PROKR2	3.06e-05	2	193	2	16901473
Pubmed	Dynamic protein kinase a activities induced by beta-adrenoceptors dictate signaling propagation for substrate phosphorylation and myocyte contraction.	ADRB1 ADRB2	3.06e-05	2	193	2	19213958
Pubmed	Identification and molecular characterization of two closely related G protein-coupled receptors activated by prokineticins/endocrine gland vascular endothelial growth factor.	PROKR1 PROKR2	3.06e-05	2	193	2	11886876
Pubmed	Investigating changes in β-adrenergic gene expression (ADRB1 and ADRB2) in Takotsubo (stress) cardiomyopathy syndrome; a pilot study.	ADRB1 ADRB2	3.06e-05	2	193	2	34716504
Pubmed	Interaction of the C9orf72-Amyotrophic Lateral Sclerosis-Related Proline-Arginine Dipeptide Repeat Protein with the RNA-Binding Protein NOVA1 Causes Decreased Expression of UNC13A Due to Enhanced Inclusion of Cryptic Exons, Which Is Reversed by Betulin Treatment.	NOVA1 UNC13A	3.06e-05	2	193	2	37887320
Pubmed	ADRB1 and ADBR2 gene polymorphisms and the ocular hypotensive response to topical betaxolol in healthy Mexican subjects.	ADRB1 ADRB2	3.06e-05	2	193	2	24749907
Pubmed	Differential contribution of beta-adrenergic receptors expressed on radiosensitive versus radioresistant cells to protection against inflammation and mortality in murine endotoxemia.	ADRB1 ADRB2	3.06e-05	2	193	2	19333138
GeneFamily	Fibronectin type III domain containing	OBSCN PTPRB PTPRF PTPRK PTPRZ1 COL7A1 ELFN1 TNN TNR	1.93e-06	160	127	9	555
GeneFamily	Protein tyrosine phosphatases, receptor type	PTPRB PTPRF PTPRK PTPRZ1	1.27e-05	21	127	4	813
GeneFamily	Prokineticin receptors	PROKR1 PROKR2	4.90e-05	2	127	2	216
GeneFamily	ATP binding cassette subfamily C	ABCC3 ABCC1 ABCC9	9.20e-05	13	127	3	807
GeneFamily	RAB, member RAS oncogene GTPases	RAB19 RAB4B RAB30 RAB4A RAB12	9.31e-05	65	127	5	388
GeneFamily	Cadherin related	CDHR2 FAT4 FAT3	2.14e-04	17	127	3	24
GeneFamily	UNC13 homologs	UNC13C UNC13A	2.91e-04	4	127	2	836
GeneFamily	C3 and PZP like, alpha-2-macroglobulin domain containing	A2ML1 C3	1.71e-03	9	127	2	1234
GeneFamily	Adrenoceptors	ADRB1 ADRB2	1.71e-03	9	127	2	169
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA13 OBSCN ADGRV1 RYR2 MELTF TRANK1 ADGRL3 FAT4 FAT3 PKHD1L1 LRP2 UNC13C PLCE1	1.68e-12	184	193	13	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA13 OBSCN ADGRV1 RYR2 MELTF TRANK1 ADGRL3 FAT4 FAT3 PKHD1L1 LRP2 UNC13C PLCE1	1.68e-12	184	193	13	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA13 OBSCN ADGRV1 RYR2 MELTF TRANK1 ADGRL3 FAT4 FAT3 PKHD1L1 LRP2 UNC13C PLCE1	1.68e-12	184	193	13	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Diaphragm-Limb_Muscle-24m\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA13 ADGRV1 RYR2 TRANK1 UPK3A FAT3 PKHD1L1 LRP2 SORCS3 UNC13C	3.69e-09	169	193	10	12bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCell	facs-Skin-Telogen-3m-Epithelial-Basal_IFE\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLK2 PAQR5 FCGBP ADRB2 SATB1 CLU RAB30 OSGIN2 MAN1C1 P2RY1	1.03e-08	188	193	10	8cc927b4c51d982fdafa04dc7393617ad9bb220e
ToppCell	Control_saline-Epithelial_airway-airway_epithelial-Airway-Club\|Control_saline / Treatment groups by lineage, cell group, cell type	IQGAP2 ADGRV1 CLU HPD PTPRZ1 A2ML1 C3 ARHGEF19 ERVV-2 SLC1A4	1.77e-08	199	193	10	5cc8b553a58669a30eb10845beb23983dcdf5a6a
ToppCell	facs-Marrow-T-cells-24m-Myeloid-basophil\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RAB19 RAB4A GPR34 SUCNR1 P2RY1 HRH4 RXFP4 TNR CDH1	2.99e-08	157	193	9	ed9c9feefc06c9536c03bedbc3397a2ee492a78e
ToppCell	facs-Marrow-T-cells-24m-Myeloid-basophil\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RAB19 RAB4A GPR34 SUCNR1 P2RY1 HRH4 RXFP4 TNR CDH1	2.99e-08	157	193	9	fddcb24776b9f86e000208bae54541b15b2adefd
ToppCell	facs-Marrow-T-cells-3m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IQGAP2 F13A1 PTPRF GPR34 MAN1C1 SUCNR1 P2RY1 HRH4 CDH1	1.02e-07	181	193	9	7286700396676fdc41d9723979b8b408177aceb9
ToppCell	facs-Skin-Telogen-3m-Epithelial-basal_cell_of_epidermis\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLK2 FCGBP ADRB2 CLU RAB30 OSGIN2 MAN1C1 HBEGF SLC7A6	1.34e-07	187	193	9	9c1013720c248ef201d010806b6e7ad24205e8ee
ToppCell	356C-Myeloid-Macrophage-FABP4+_Macrophage\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	ERCC2 PTPRF PTPRK UPK3A DNASE1 SYNE1 ABCC9 MYO1B	5.57e-07	162	193	8	2259e9536147e9cdee772e3a30ba7d104573262c
ToppCell	5'-Airway_Nasal_SMG-Epithelial\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PLK2 SLC28A3 PROM1 FCGBP CLU PTPRZ1 C3 TCN1	5.84e-07	163	193	8	454a5e87e2f9f66e38cc5aa1b433c47b54c9be42
ToppCell	5'-Airway_Nasal_SMG-Epithelial-Epithelial_transtional-secretory\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PLK2 SLC28A3 PROM1 FCGBP CLU PTPRZ1 C3 TCN1	5.84e-07	163	193	8	f6847f47a8856c0d4136c1af317432d45eccfde9
ToppCell	5'-Airway_Nasal_SMG\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PLK2 SLC28A3 PROM1 FCGBP CLU PTPRZ1 C3 TCN1	5.84e-07	163	193	8	d8450bf9c6d2ec5dd1472952c9e65f82f995337a
ToppCell	droplet-Lung-nan-18m-Lymphocytic-plasma_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPO11 UPK3A DNASE1 PKD1L3 TG NBAS DMRT2 TSBP1	5.84e-07	163	193	8	5efecdd8a069a822bc9d35b407092925a865e629
ToppCell	5'-Airway_Nasal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_acinar_cell-SMG_duct\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PLK2 SLC28A3 PROM1 FCGBP CLU PTPRZ1 C3 TCN1	5.84e-07	163	193	8	a1fbefe53523a9879a4d4b493071059798b5f917
ToppCell	5'-Airway_Nasal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_acinar_cell\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PLK2 SLC28A3 PROM1 FCGBP CLU PTPRZ1 C3 TCN1	5.84e-07	163	193	8	d9bd9d90cfa4e85d5ea51f8f3ee14a700571f508
ToppCell	5'-Airway_Nasal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_acinar_cell-SMG_duct-SMG_duct_L.0.6.2.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PLK2 SLC28A3 PROM1 FCGBP CLU PTPRZ1 C3 TCN1	5.84e-07	163	193	8	be6cc44df9a2b10dce1a353717c279c3558f8fec
ToppCell	droplet-Lung-nan-18m-Lymphocytic-Plasma_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPO11 UPK3A DNASE1 PKD1L3 TG NBAS DMRT2 TSBP1	5.84e-07	163	193	8	0d94a427f86e62aba12c397c6d7b8cd297f3a0e5
ToppCell	droplet-Lung-18m-Hematologic-lymphocytic-plasma_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SPO11 UPK3A DNASE1 PKD1L3 TG NBAS DMRT2 TSBP1	6.11e-07	164	193	8	b92e7c91910d518627376166c6ea9ed333b3d07e
ToppCell	droplet-Lung-18m-Hematologic-lymphocytic-plasma_cell-plasma_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SPO11 UPK3A DNASE1 PKD1L3 TG NBAS DMRT2 TSBP1	6.11e-07	164	193	8	a1e43c6b3e2553f5604100db6e92bf244b70c36d
ToppCell	droplet-Spleen-nan-3m-Myeloid-macrophage_dendritic_cell_progenitor\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAS1 OBSCN PAQR5 MVB12A PTPRF MAN1C1 PELI2 CDH1	9.98e-07	175	193	8	21bc0e59a9509d38751ce6aad2325f341bc70eff
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK11 ABCA13 EVC PROM1 ADGRL3 SYNE1 FAT3 DNAH17	1.04e-06	176	193	8	327a3e81b724252e36d786de92a3ffd721ea6d7b
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Hpse_Sema3c\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	DOCK11 PAQR5 PROKR2 KLHL14 ELFN1 TNN UNC13C	1.06e-06	122	193	7	eae9d94f8510ac0f434942451d55c7260977b178
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK11 ABCA13 EVC PROM1 ADGRL3 SYNE1 FAT3 DNAH17	1.09e-06	177	193	8	da8802a6351d3e510822f82e2fde8a4314a2216e
ToppCell	E18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CLU C3 PKHD1L1 MST1R FAM180A LRP2 UNC13C PLCE1	1.13e-06	178	193	8	bcbdd45a2307f8aea14122fa0144b96b1f6eec48
ToppCell	E18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CLU C3 PKHD1L1 MST1R FAM180A LRP2 UNC13C PLCE1	1.13e-06	178	193	8	c413861148129be1ee94f2ceb5999840217eebe5
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_B-B_atypical-male\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	KBTBD8 ARMCX2 PTPN1 PTPRB TECPR2 ADCK1 ARHGAP5 PLCE1	1.18e-06	179	193	8	5be883d7d0be3180bb9844e4a757f0dd247294e4
ToppCell	facs-Marrow-B-cells-3m-Myeloid-CD4+_macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OBSCN PAQR5 MVB12A PTPRF MAN1C1 ARHGAP5 GPR137B CDH1	1.23e-06	180	193	8	bf8d13d4db1af55b8c9fe16aaccf8743e000e005
ToppCell	facs-Marrow-B-cells-3m-Myeloid-macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OBSCN PAQR5 MVB12A PTPRF MAN1C1 ARHGAP5 GPR137B CDH1	1.23e-06	180	193	8	82965ed1b72a1873c24dd4553d39681596057316
ToppCell	facs-Marrow-B-cells-3m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OBSCN PAQR5 MVB12A PTPRF MAN1C1 ARHGAP5 GPR137B CDH1	1.23e-06	180	193	8	839defb40f7cfb2711e9025194de636533f51bcd
ToppCell	PND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CLU KCNJ5 C3 ZBTB12 PKHD1L1 MST1R LRP2 PLCE1	1.29e-06	181	193	8	330d4322f4c4373f706273c1f4e218b59051b7fd
ToppCell	PND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CLU KCNJ5 C3 ZBTB12 PKHD1L1 MST1R LRP2 PLCE1	1.29e-06	181	193	8	3f4d5d79c1286614514b0e8134079d6128a2a23e
ToppCell	PBMC-Mild-Myeloid-Neutrophil-immature_Neutrophil-Neu_4\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ABCA13 ADGRV1 A2ML1 NOVA1 NOVA2 TCN1 FAT3	1.32e-06	126	193	7	69b2525b92d1c7c35b21cc701f5fa52a9c1b94bb
ToppCell	PBMC-Mild-Myeloid-Neutrophil-immature_Neutrophil-Neu_4\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	ABCA13 ADGRV1 A2ML1 NOVA1 NOVA2 TCN1 FAT3	1.32e-06	126	193	7	6cb89754010d64875e115da6c5805efac7a4a82d
ToppCell	Serous\|World / shred by cell class for bronchial biopsy	PLK2 IQGAP2 PHB1 PROM1 FCGBP CLU C3 TCN1	1.45e-06	184	193	8	09d0d1525c11dd326efd942684c03f79d992cf3b
ToppCell	droplet-Marrow-BM-1m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RAB19 RAB4A GPR34 SUCNR1 CELA3B P2RY1 HRH4 CDH1	1.51e-06	185	193	8	5527fa9d2e0b2f3607602e18ba94de4e9bbc6824
ToppCell	droplet-Lung-1m-Hematologic-myeloid-intermediate_monocyte-intermediate_monocyte_l14\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ACP2 TXNL4B PHLPP1 OSGIN2 TCN1 ADCK1 GTF2H1	1.80e-06	132	193	7	14a512f433315892bf0326419f23d0d5919d01ec
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DOCK11 PROM1 NEK3 SATB1 KCNJ5 COL7A1 ELFN1 UNC13C	2.08e-06	193	193	8	c7e9e6e4bf5e07c9cbdf1aa7c8828f4b2500e3ff
ToppCell	Fetal_29-31_weeks-Endothelial-capillary_endothelial_cell_(Cap1)-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	PLK2 NEK3 ADRB1 PTPRB ADGRL3 NOVA2 P2RY1 SLC35F2	2.42e-06	197	193	8	b2b7f8dc8ca421441e4c99c4f5d18fbc1668d79f
ToppCell	Bronchial-NucSeq-Immune_Myeloid-Macrophage_other-Macro_AW_CX3CR1\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	F13A1 FCGBP GPR34 SUCNR1 PKD1L3 TASL ARHGAP4 P2RY1	2.42e-06	197	193	8	0a404b4494a2246d5a92299235056f0fda4d2b48
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ABCC3 EPS8 PROM1 CLU C3 UBR4 NOX4 LRP2	2.71e-06	200	193	8	105564ee05bd11685b5747ee32d5350cf3c2e2e1
ToppCell	facs-Marrow-KLS-18m-Lymphocytic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC28A3 ADGRV1 KCNH6 ADRB1 PTPRB PTPRK ABCC9	5.00e-06	154	193	7	37765512dfae557b9f6eb30a29463b93682a4404
ToppCell	droplet-Liver-Hepatocytes-24m-Epithelial-Hepatocyte_(Pericentral_and_Periportal)\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLU HPD DNASE1 TCN1 NOX4 MYO1B SUCNR1	5.00e-06	154	193	7	a5289000597068ee8d559f89bce7bce31f35dd57
ToppCell	Frontal_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Sst\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	SATB1 PROKR2 KLHL14 DMRT2 ELFN1 UNC13C	5.21e-06	101	193	6	cf52c93f523c5f25bd45519a1444ce7bd1d8b577
ToppCell	390C-Myeloid-Macrophage-SPP1+_Macrophage_2\|390C / Donor, Lineage, Cell class and subclass (all cells)	F13A1 PTPN1 GPR34 HBEGF UBR4 SUCNR1 DNAH17	5.22e-06	155	193	7	15bacd06cc2b02b13c85bb71c5b758e5ff613e80
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Myocytic-Pericyte_2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	EPS8 RYR2 ABCC9 MYO1B CELA3B ELFN1 PLCE1	5.68e-06	157	193	7	bfec34182f052cf1c0d847ba53ea335d4d1190de
ToppCell	droplet-Lung-3m-Hematologic-myeloid-interstitial_macrophage\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ABCC3 EPS8 F13A1 GPR34 MAN1C1 TSBP1 UNC13A	5.92e-06	158	193	7	9a6d9b541446a6aa9f8ed040b330dbb5c6447076
ToppCell	droplet-Lung-3m-Hematologic-myeloid-interstitial_macrophage-interstitial_macrophage_l12\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ABCC3 EPS8 F13A1 GPR34 MAN1C1 TSBP1 UNC13A	5.92e-06	158	193	7	2438713d2a7e32c647ab3384237ed614f4ec8fec
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL6A5 ADGRV1 RYR2 PTPRZ1 FAT3 PKHD1L1 LRP2	6.43e-06	160	193	7	c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL6A5 ADGRV1 RYR2 PTPRZ1 FAT3 PKHD1L1 LRP2	6.43e-06	160	193	7	25c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-3.5_mon-Neuronal-Cajal-Retzius\|3.5_mon / Sample Type, Dataset, Time_group, and Cell type.	SLC22A15 CLU KCNJ5 P2RY1 ELFN1 SLC35F2 CDH18	7.26e-06	163	193	7	c1484e4de8b10e2f5fb14a7c02b2a015ffe0305e
ToppCell	wk_15-18-Mesenchymal-Myofibro_&_SMC-Myofibro_3\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	RIDA PROM1 TAS2R4 MELTF FAT4 FAT3 UNC13C	7.55e-06	164	193	7	583dda853cee9491dbdcb228c23d8deadc20eb08
ToppCell	facs-Marrow-T_cells-18m-Myeloid-basophil\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RAB19 GPR34 SUCNR1 CELA3B P2RY1 HRH4 CDH1	8.18e-06	166	193	7	c22b0f3bf990d94b615a3aacee5de548da2db628
ToppCell	356C-Myeloid-Macrophage-FABP4+_Macrophage\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	ERCC2 PTPRF PTPRK DNASE1 SYNE1 ABCC9 MYO1B	8.18e-06	166	193	7	89e2b8453180983533faccb4275867861876d7ee
ToppCell	facs-Marrow-T_cells-18m-Myeloid-basophil\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RAB19 GPR34 SUCNR1 CELA3B P2RY1 HRH4 CDH1	8.18e-06	166	193	7	0975fc165bcc7e85f053d9d0244fffe407c23571
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	KCNU1 HPD NWD1 NOX4 LRP2 UNC13A CDH18	8.50e-06	167	193	7	3edb0570e583bb527165bcd8a4c25a042054043b
ToppCell	PND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	IL22RA1 CLU C3 PKHD1L1 FAM180A UNC13C PLCE1	8.50e-06	167	193	7	7abc785e688a384672d7fb5a62d32538fe7e5a51
ToppCell	PND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	IL22RA1 CLU C3 PKHD1L1 FAM180A UNC13C PLCE1	8.50e-06	167	193	7	d50311b1f66f143bae4c4cf50e2e9b13c85d6920
ToppCell	Club_cells-IPF_03\|World / lung cells shred on cell class, cell subclass, sample id	PLK2 PROM1 FCGBP CLU C3 TCN1 IGHG1	8.50e-06	167	193	7	dbdaaeb3bd9139cb008d9fe24ec031fc5628f136
ToppCell	COVID-19-Heart-CM_+_Macrophage\|Heart / Disease (COVID-19 only), tissue and cell type	ABCC3 IQGAP2 OBSCN F13A1 RYR2 FCGBP TG	9.55e-06	170	193	7	4232fe937909f93d3736988c707b8f95ce993398
ToppCell	PND03-Immune-Immune_Myeloid-Megakaryocyte/Platelet\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	IQGAP2 SPO11 PROKR1 CLU KCNJ5 PKD1L3 P2RY1	1.03e-05	172	193	7	e39ea2f4edbf36ebf9604fa6f9349081859c596c
ToppCell	PND03-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	IQGAP2 SPO11 PROKR1 CLU KCNJ5 PKD1L3 P2RY1	1.03e-05	172	193	7	875ea290840e835952623b905eb610f3c71456d2
ToppCell	PND03-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet-Megakaryocyte/Platelet_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	IQGAP2 SPO11 PROKR1 CLU KCNJ5 PKD1L3 P2RY1	1.03e-05	172	193	7	bcc50bed47465daa953ba91f17d1ee4c947ab461
ToppCell	droplet-Spleen-SPLEEN-30m-Myeloid-macrophage_dendritic_cell_progenitor\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IQGAP2 PAQR5 MVB12A PTPRF PELI2 ARHGAP5 CDH1	1.03e-05	172	193	7	30916a902c151907745756d14327e24adc34afef
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Hpse_Cbln4\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	DOCK11 PROKR2 KLHL14 DMRT2 ELFN1 UNC13C	1.10e-05	115	193	6	ac73aa06e617ed791c6ae9e38189bac74188c27b
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Degenerative_Ascending_Thin_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	EVC ADGRV1 MELTF FCGBP CLU FAT3 DNAH17	1.11e-05	174	193	7	46bd0ef7d0541386de7a901d85d53d0176dc92bf
ToppCell	droplet-Marrow-nan-3m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLK2 DOCK11 ABCA13 SMPDL3B PHLPP1 C3 SYNE1	1.15e-05	175	193	7	cf53a15bfb37b6019e7052ffdf594a9ac040900e
ToppCell	droplet-Lung-18m-Hematologic-myeloid-classical_monocyte_proliferating-classical_monocyte_proliferating_l2\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MCM3 F13A1 RNF157 KIF3B PAXIP1 SLC38A7 SLC35F2	1.20e-05	176	193	7	1510cdfcfb46ce1196a1220c07fb5f3986c81b78
ToppCell	droplet-Marrow-nan-3m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RAB19 RAB4A GPR34 FAT3 P2RY1 HRH4 CDH1	1.24e-05	177	193	7	c1f838e425ebb04482829b1957e3c1347127e6de
ToppCell	facs-Marrow-T-cells-3m-Myeloid-basophil\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RAB19 GPR34 FAT3 SUCNR1 P2RY1 HRH4 CDH1	1.29e-05	178	193	7	41745a589567ca5ea6d06331f4c8da03595b5f5c
ToppCell	facs-Marrow-T-cells-3m-Myeloid-basophil\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RAB19 GPR34 FAT3 SUCNR1 P2RY1 HRH4 CDH1	1.29e-05	178	193	7	eb940dd64c973f68bcaad6069d3bd56383329db5
ToppCell	NS-critical-LOC-Epithelial-Ionocyte\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	ADRB1 SMPDL3B NOVA1 MAN1C1 FAT3 DMRT2 UNC13C	1.34e-05	179	193	7	65a96bee7bc28f5bfc20f0fd92bcc0ab2eb5e06c
ToppCell	TCGA-Mesothelium-Primary_Tumor-Mesothelioma-Epitheliod\|TCGA-Mesothelium / Sample_Type by Project: Shred V9	SLC28A3 TRANK1 PTPRF C3 PKHD1L1 MST1R ZBTB44	1.49e-05	182	193	7	bb1f815718397de96682697fcbd6014a992a28f7
ToppCell	facs-Skin-Telogen-3m-Epithelial-nan\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PAQR5 ADRB2 SATB1 CLU ABCC1 HBEGF CDH1	1.54e-05	183	193	7	26b18d1cc5d98f185176e100bafb9bc9081c66f7
ToppCell	COPD-Epithelial-ATII\|World / Disease state, Lineage and Cell class	ADGRV1 PTPRK SYNE1 ABCC9 MYO1B LRP2 CDH1	1.54e-05	183	193	7	8e9aab4eeec2e282c2cab9bfca6dbf40d660c7b9
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK11 ABCA13 EVC PROM1 ADGRL3 FAT3 DNAH17	1.54e-05	183	193	7	92fbd83a9d13ee91065cbd479fb298f1fd564568
ToppCell	Monocytes-IL1B+_Monocytes\|Monocytes / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	PLK2 F13A1 SATB1 CYB5D1 HBEGF IGHG1 DNAH17	1.65e-05	185	193	7	cbe54b605f417a01b3b5d2ec75565ee3b5a9ba06
ToppCell	facs-Thymus-Flowthrough-3m-Lymphocytic-DN_to_DP_transition_(most_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPO11 IP6K1 F13A1 RNF157 SATB1 MAD1L1 CFAP74	1.65e-05	185	193	7	dc59b8dc459a3c444c9634a0d438cbef54c40036
ToppCell	droplet-Kidney-nan-18m-Epithelial\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RIDA PROM1 PTPRF DNASE1 NOX4 ARHGAP5 LRP2	1.77e-05	187	193	7	236e9857729670e87eed30fad58f49e1f56e4a85
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK11 ABCA13 EVC ADGRV1 MELTF FCGBP DNAH17	1.77e-05	187	193	7	c41a2c81dd2ceef303f39f699032aa7d6ea67cf0
ToppCell	Fetal_29-31_weeks-Mesenchymal-pericyte_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	EPS8 OBSCN RYR2 ABCC9 MYO1B DMRT2 PLCE1	1.77e-05	187	193	7	a2bf958ea59c359a265bfa437d59315e1920cdd4
ToppCell	PCW_07-8.5-Epithelial-Epithelial_alveolar-distal-epi_SFTPC^high_distal_(9)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	ADGRV1 IL22RA1 SMPDL3B PTPRZ1 ARHGEF19 LRP2 CDH1	1.90e-05	189	193	7	5d9da836ce4308b8458bb3be3871a0aca734b6cd
ToppCell	E17.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_myogenic_precursor_(Axin2+)\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ARMCX2 ADGRL3 NOX4 ABCC9 MYO1B IGF2R PLCE1	1.90e-05	189	193	7	26cfe5b7e7f477f225f4e9f25f983f432f01e183
ToppCell	facs-Skin-Skin_Anagen-18m-Epithelial-Basal_IFE\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLK2 PAQR5 FCGBP ADRB2 MAN1C1 HBEGF SLC1A4	1.90e-05	189	193	7	1cfc1fe27c4b57b4e52700fa8f679ce172cee5a9
ToppCell	E17.5-Mesenchymal-developing_mesenchymal_cell\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ARMCX2 ADGRL3 NOX4 ABCC9 MYO1B IGF2R PLCE1	1.96e-05	190	193	7	2ab604d35456beba71c25511e0f819000e6642d2
ToppCell	E18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ARMCX2 HBEGF ABCC9 MYO1B PLEKHG2 IGF2R PLCE1	1.96e-05	190	193	7	951e067d14412db67dc3babcdf61e41717d7b429
ToppCell	BAL-Control-Epithelial\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	ABCA13 PROM1 PTPRF CLU STOML3 NWD1 CFAP74	2.03e-05	191	193	7	9f19098f260d5542aa8ba7eb6f91b44d0db6e0a4
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ABCC3 DOCK11 ABCA13 EVC PROM1 ADGRL3 FAT3	2.03e-05	191	193	7	d0e9afe7b6334dd515d3e68892efdc76347a55e5
ToppCell	BAL-Control-Epithelial-Epithelial-Ciliated-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ABCA13 PROM1 PTPRF CLU STOML3 NWD1 CFAP74	2.03e-05	191	193	7	fa9f8b50bfc7911c858bc2f9dcd204873d97ac61
ToppCell	BAL-Control-Epithelial-Epithelial-Ciliated\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ABCA13 PROM1 PTPRF CLU STOML3 NWD1 CFAP74	2.03e-05	191	193	7	c4b223b33c020a064f576711a3d700eb60a2d737
ToppCell	BAL-Control-Epithelial\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ABCA13 PROM1 PTPRF CLU STOML3 NWD1 CFAP74	2.03e-05	191	193	7	5129f778a9283bfac4ff322c21c5ca71da4b7174
ToppCell	BAL-Control-Epithelial-Epithelial\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	ABCA13 PROM1 PTPRF CLU STOML3 NWD1 CFAP74	2.03e-05	191	193	7	df8a1a6e78aa0cb941b94cb676bd6891d79f3687
ToppCell	Influenza_Severe-Non-classical_Monocyte\|Influenza_Severe / Disease group and Cell class	ABCC3 EPS8 ACP2 C3 UPK3A P2RY1 GPR137B	2.03e-05	191	193	7	197edf6feb1cfc71d88e532d74f77305a42a3486
ToppCell	Control-Epithelial\|Control / Disease group,lineage and cell class （2021.01.30）	ABCA13 PROM1 PTPRF CLU STOML3 NWD1 CFAP74	2.03e-05	191	193	7	b78547dae8328244a47c83346447bdd787efbcae
ToppCell	BAL-Control-Epithelial-Epithelial\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ABCA13 PROM1 PTPRF CLU STOML3 NWD1 CFAP74	2.03e-05	191	193	7	c50d6a1a6209ed4157f7c00fc24d4ecb43790f44
ToppCell	COVID-19-Heart-EC_(POSTN)\|Heart / Disease (COVID-19 only), tissue and cell type	PAQR5 PTPRB PTPRF CLU PELI2 PKHD1L1 UNC13C	2.10e-05	192	193	7	c0c34785a7bdf461722029b322e9184e3d9b3c26
ToppCell	facs-Skin-Anagen-3m-Epithelial-basal_cell_of_epidermis\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLK2 MCM3 FCGBP ADRB2 CLU PTPRZ1 MAN1C1	2.10e-05	192	193	7	ec1fd2fb6e71f87189d66261909a84e2be63cacb
ToppCell	Fetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ADGRL3 NOVA1 FAT4 FAT3 GPR137C UNC13C GREB1	2.10e-05	192	193	7	72881b280a415e65f87a80ca1369cbb0b722a0c4
ToppCell	Tracheal-10x3prime_v2-Immune_Lymphocytic-B-B_plasma-B_plasma_IgG\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	SMPDL3B RAB30 GRK6 PKHD1L1 FICD IGHG1 SLC35F2	2.10e-05	192	193	7	ca4d8e540d9e6fa47ecf97648cbd5abfc7ab7f85
Drug	AG-013608 [351320-38-2]; Up 200; 10uM; MCF7; HT_HG-U133A	ABCC3 KCNH6 ADRB1 KCNJ5 CACNA1I GPR6 HBEGF SYNE1 TASL SLC1A4 MST1R	6.74e-07	193	189	11	5904_UP
Drug	Viomycin sulfate [37883-00-4]; Up 200; 5.2uM; MCF7; HT_HG-U133A	ABCC3 MORN1 C3 CACNA1I UPK3A NOVA2 MAN1C1 TASL SLC1A4 P2RY1	6.74e-06	199	189	10	3541_UP
Drug	2-fluoronorepinephrine	ADRB1 ADRB2 HRH4	1.11e-05	6	189	3	CID000172745
Drug	pimozide	RYR2 KCNH6 ADRB1 ADRB2 HPD CACNA1I DRD5 PKD1L3	1.12e-05	127	189	8	CID000016362
Drug	2-(oxalylamino)benzoic acid	PTPN1 PTPRB PTPRF	1.92e-05	7	189	3	ctd:C405943
Drug	SKF 83566	DRD5 GRK6 P2RY1 HRH4	2.01e-05	20	189	4	CID000001243
Drug	2b1g	F13A1 SYNE1 NOX4 TG MMEL1 LRP2	2.77e-05	71	189	6	CID011963491
Drug	hydroxyphenylglycine	ADRB2 HPD C3 RNF139	2.99e-05	22	189	4	CID000067149
Drug	Homosalate [118-56-9]; Up 200; 15.2uM; MCF7; HT_HG-U133A	ABCC3 TAS2R4 MELTF KCNJ5 FAT4 MAN1C1 UBR4 SLC1A4 P2RY1	3.83e-05	195	189	9	4355_UP
Drug	LY294002; Down 200; 10uM; MCF7; HG-U133A	GCKR F13A1 RAB30 COL7A1 GRK6 IDS SLC7A6 GREB1 CDH18	3.99e-05	196	189	9	328_DN
Drug	0179445-0000 [211246-22-9]; Up 200; 1uM; MCF7; HT_HG-U133A	ABCC3 CDHR2 RYR2 TRANK1 KCNJ5 HBEGF UBR4 GREB1 UNC13A	4.15e-05	197	189	9	4758_UP
Drug	Acyclovir [59277-89-3]; Up 200; 17.8uM; MCF7; HT_HG-U133A	MORN1 KCNJ5 CACNA1I GPR6 MYO1B IDS TASL SLC1A4 PDE12	4.15e-05	197	189	9	1543_UP
Drug	PF-00875133-00 [351322-64-0]; Down 200; 10uM; MCF7; HT_HG-U133A	ABCC3 MORN1 SMPDL3B TECPR2 RAB30 CACNA1I NOVA1 HBEGF CFAP74	4.15e-05	197	189	9	5923_DN
Drug	AG-013608 [351320-38-2]; Down 200; 10uM; MCF7; HT_HG-U133A	GCKR F13A1 CACNA1I ADGRL3 UBR4 ARHGAP4 CDH1 SNRNP200 CDH18	4.31e-05	198	189	9	5944_DN
Drug	nisoldipine	RYR2 ADRB1 CACNA1I HBEGF PKD1L3 POLR3E	4.73e-05	78	189	6	CID000004499
Drug	fluorescein	ABCC3 MRPS22 HPD DNASE1 ABCC1 MST1R TNN RNF139	5.18e-05	157	189	8	CID000016850
Drug	piperoxan	ADRB1 ADRB2 PHLPP1 DRD5	5.96e-05	26	189	4	CID000006040
Drug	angiotensin (1-7)	MAS1 ADRB1 NOX4 MMEL1 LRP2	6.44e-05	51	189	5	CID000123805
Drug	DO 710	ADRB1 ADRB2 DRD5	6.47e-05	10	189	3	CID003084985
Drug	Carteolol	ADRB1 ADRB2	6.85e-05	2	189	2	DB00521
Drug	cicloprolol	ADRB1 ADRB2	6.85e-05	2	189	2	CID000146294
Drug	ferulinolol	ADRB1 ADRB2	6.85e-05	2	189	2	ctd:C112517
Drug	Timolol	ADRB1 ADRB2	6.85e-05	2	189	2	DB00373
Drug	Metoprolol	ADRB1 ADRB2	6.85e-05	2	189	2	DB00264
Drug	Oxprenolol	ADRB1 ADRB2	6.85e-05	2	189	2	DB01580
Drug	Betaxolol	ADRB1 ADRB2	6.85e-05	2	189	2	DB00195
Drug	Dihydroalprenolol	ADRB1 ADRB2	6.85e-05	2	189	2	ctd:D004082
Drug	Penbutolol	ADRB1 ADRB2	6.85e-05	2	189	2	DB01359
Drug	Pirbuterol	ADRB1 ADRB2	6.85e-05	2	189	2	DB01291
Drug	Metipranolol	ADRB1 ADRB2	6.85e-05	2	189	2	DB01214
Drug	Levobunolol	ADRB1 ADRB2	6.85e-05	2	189	2	DB01210
Drug	Nadolol	ADRB1 ADRB2	6.85e-05	2	189	2	DB01203
Drug	Acebutolol	ADRB1 ADRB2	6.85e-05	2	189	2	DB01193
Drug	KMUP 880602	ADRB1 ADRB2	6.85e-05	2	189	2	ctd:C466918
Drug	Spirendolol	ADRB1 ADRB2	6.85e-05	2	189	2	CID000068857
Drug	Carteolol	ADRB1 ADRB2	6.85e-05	2	189	2	ctd:D002354
Drug	Dobutamine	ADRB1 ADRB2	6.85e-05	2	189	2	DB00841
Drug	Bisoprolol	ADRB1 ADRB2	6.85e-05	2	189	2	DB00612
Drug	LK 204-545	ADRB1 ADRB2	6.85e-05	2	189	2	CID005311116
Drug	befunolol	ADRB1 ADRB2	6.85e-05	2	189	2	ctd:C006034
Drug	ethyl diethoxyacetate	C3 HBEGF	6.85e-05	2	189	2	CID000080169
Drug	Salbutamol	ADRB1 ADRB2	6.85e-05	2	189	2	DB01001
Drug	Nebivolol	ADRB1 ADRB2	6.85e-05	2	189	2	DB04861
Drug	N-(4-(2-hydroxy-3-(2-methoxy-1-oxyethylaminobenzene)propoxy))benzaldehyde	ADRB1 ADRB2	6.85e-05	2	189	2	ctd:C435583
Drug	B 24-76	ADRB1 ADRB2	6.85e-05	2	189	2	ctd:C058041
Drug	2-chloroethylamine	ADRB1 ADRB2	6.85e-05	2	189	2	ctd:C010076
Drug	brilliant blue	TXNL4B A2ML1 PNKD CELA3B	6.95e-05	27	189	4	CID000017559
Drug	methoxyphenamine	ADRB1 ADRB2 KCNJ5	1.17e-04	12	189	3	CID000004117
Drug	BDF 6143	ADRB1 ADRB2 HRH4	1.17e-04	12	189	3	CID000131283
Drug	cyclofenil	F13A1 TXNL4B COL7A1 TNR	1.21e-04	31	189	4	CID000002898
Drug	dimethindene	ADRB1 ADRB2 HRH4	1.51e-04	13	189	3	CID000021855
Drug	Bulbokaprin	ADRB1 ADRB2 DRD5	1.51e-04	13	189	3	CID000009276
Drug	NSC243743	PHB1 HPD PHLPP1 SYNE1	1.76e-04	34	189	4	CID000001064
Drug	NSC302991	ABCC3 ERCC2 SETX PKDREJ PHB1 SATB1 CLU CUL4A ABCC1 ABCC9 PRKDC	1.88e-04	353	189	11	CID000002538
Drug	Mebendazole [31431-39-7]; Up 200; 13.6uM; MCF7; HT_HG-U133A	ABCC3 MORN1 TECPR2 HBEGF GRK6 SLC1A4 MST1R GREB1	1.88e-04	189	189	8	2300_UP
Drug	benzimidazol-2-one	ADRB1 ADRB2 DRD5	1.92e-04	14	189	3	CID000162542
Drug	thioinosine	ABCC3 ABCC1 SYNE1 TG	1.97e-04	35	189	4	CID000676166
Drug	Sotalol	ADRB1 ADRB2	2.05e-04	3	189	2	DB00489
Drug	arbutamine	ADRB1 ADRB2	2.05e-04	3	189	2	ctd:C076559
Drug	N-(3-hydroxy-1-(naphthalen-1-yl)-1,8,11-trioxa-5-azatridecan-13-yl)-6-(2-(2-(4,4-difluoro-4,4a-dihydro-5-(thiophen-2-yl)-4-bora-3a,4a-diaza-s-indacene-3-yl)vinyl)phenoxyacetamido)hexanamide	ADRB1 ADRB2	2.05e-04	3	189	2	ctd:C568515
Drug	3-iodopindolol	ADRB1 ADRB2	2.05e-04	3	189	2	CID000123825
Drug	p-azidobenzylcarazolol	ADRB1 ADRB2	2.05e-04	3	189	2	CID000133262
Drug	Bevantolol	ADRB1 ADRB2	2.05e-04	3	189	2	DB01295
Drug	Fenoterol	ADRB1 ADRB2	2.05e-04	3	189	2	DB01288
Drug	LCB 2183	ADRB1 ADRB2	2.05e-04	3	189	2	CID000133046
Drug	U-43,465F	ADRB1 ADRB2	2.05e-04	3	189	2	CID000134388
Drug	C 27	C3 ARHGAP4	2.05e-04	3	189	2	CID006438326
Drug	Arbutamine	ADRB1 ADRB2	2.05e-04	3	189	2	DB01102
Drug	broxaterol	ADRB1 ADRB2	2.05e-04	3	189	2	ctd:C045916
Drug	pBABC	ADRB1 ADRB2	2.05e-04	3	189	2	CID000126676
Drug	hmimBF4	NOVA1 NOVA2	2.05e-04	3	189	2	CID002734179
Drug	EXP063	ADRB1 ADRB2	2.05e-04	3	189	2	CID003037493
Drug	ICYP-azide-2	ADRB1 ADRB2	2.05e-04	3	189	2	CID003036190
Drug	BAM-CYP	ADRB1 ADRB2	2.05e-04	3	189	2	CID000125252
Drug	butofilolol	ADRB1 ADRB2	2.05e-04	3	189	2	CID000068838
Drug	soquinolol	ADRB1 ADRB2	2.05e-04	3	189	2	CID000068811
Drug	CS 476	ADRB1 ADRB2	2.05e-04	3	189	2	CID000100459
Drug	exaprolol	ADRB1 ADRB2	2.05e-04	3	189	2	CID000065484
Drug	Alprenolol	ADRB1 ADRB2	2.05e-04	3	189	2	DB00866
Drug	AHR-9377	ADRB1 ADRB2	2.05e-04	3	189	2	CID000054961
Drug	dicyclopropyl ketoxime	ADRB1 ADRB2	2.05e-04	3	189	2	CID000015072
Drug	Oberadilol	ADRB1 ADRB2	2.05e-04	3	189	2	CID003047798
Drug	DMF 3	C3 TG	2.05e-04	3	189	2	CID000007026
Drug	CGP-12177-NBD	ADRB1 ADRB2	2.05e-04	3	189	2	CID003081105
Drug	methylthiosemicarbazide	C3 HBEGF	2.05e-04	3	189	2	CID002723853
Drug	Bupranolol	ADRB1 ADRB2	2.05e-04	3	189	2	DB08808
Drug	4-phenylthiosemicarbazide	C3 SYNE1	2.05e-04	3	189	2	CID000730679
Drug	p-azidoclonidine	ADRB1 ADRB2	2.05e-04	3	189	2	CID003035819
Drug	1-octyl-3-methylimidazolium tetrafluoroborate	NOVA1 NOVA2	2.05e-04	3	189	2	CID011460221
Drug	ICYP-azide-1	ADRB1 ADRB2	2.05e-04	3	189	2	CID000133837
Drug	AC1L4W2Z	ADRB1 ADRB2	2.05e-04	3	189	2	CID000193350
Drug	Guanine Nucleotides	ADRB1 ADRB2	2.05e-04	3	189	2	ctd:D006150
Drug	bucindolol	ADRB1 ADRB2	2.05e-04	3	189	2	ctd:C024307
Drug	H 216/44	ADRB1 ADRB2	2.05e-04	3	189	2	CID000130141
Drug	Iodocyanopindolol	ADRB1 ADRB2	2.05e-04	3	189	2	ctd:D020120
Drug	AC1L1TT8	ADRB1 ADRB2	2.05e-04	3	189	2	CID000060729
Drug	ADATN	ADRB1 ADRB2	2.05e-04	3	189	2	CID000133861
Drug	5-carboxyfluorescein diacetate	ABCC3 ABCC1	2.05e-04	3	189	2	ctd:C084577
Drug	Vitamin K2 [11032-49-8]; Up 200; 9uM; MCF7; HT_HG-U133A	MORN1 SLC28A3 ADGRL3 NOVA2 FAT4 UBR4 SORCS3 SNRNP200	2.10e-04	192	189	8	4356_UP
Drug	Simvastatin [79902-63-9]; Down 200; 9.6uM; PC3; HT_HG-U133A	CDHR2 SMPDL3B GOLGA2 ROGDI SYNE1 TASL PDE12 CDH1	2.25e-04	194	189	8	4244_DN
Disease	Hereditary Diffuse Gastric Cancer	ERCC2 PHB1 ADRB1 FCGBP ADRB2 PTPRF FAT4 HBEGF NBAS HRH4 CDH1 PLCE1	3.72e-07	293	185	12	C1708349
Disease	Stomach Neoplasms	ERCC2 PHB1 ADRB1 FCGBP ADRB2 PTPRF FAT4 HBEGF NBAS HRH4 CDH1 PLCE1	4.30e-07	297	185	12	C0038356
Disease	Malignant neoplasm of stomach	ERCC2 PHB1 ADRB1 FCGBP ADRB2 PTPRF FAT4 HBEGF NBAS HRH4 CDH1 PLCE1	4.78e-07	300	185	12	C0024623
Disease	X-13684 measurement	ABCC1 SLC1A4 GTF2H1	1.33e-05	8	185	3	EFO_0800737
Disease	short-term memory	PLK2 PTPRK ADGRL3 GPR6 GPR137B CDH18	1.42e-05	83	185	6	EFO_0004335
Disease	amyotrophic lateral sclerosis (biomarker_via_orthology)	PTPRZ1 C3 IGF2R	6.62e-05	13	185	3	DOID:332 (biomarker_via_orthology)
Disease	Colorectal Neoplasms	ABCC3 ERCC2 ABCA13 SLC22A15 PROM1 ABCC1 COL7A1 SYNE1 CDH1	6.78e-05	277	185	9	C0009404
Disease	Disease Exacerbation	ABCA13 PHB1 PTPRF ABCC1 COL7A1 NBAS CDH1	8.58e-05	165	185	7	C0235874
Disease	amino acid measurement	SETX GCKR RYR2 NEK3 PTPRB CLU FAT4 SYNE1 PNKD SLC1A4 NBAS LRP2 UNC13C PRKDC	1.04e-04	678	185	14	EFO_0005134
Disease	lung adenocarcinoma (implicated_via_orthology)	IGF2R CDH1	1.17e-04	3	185	2	DOID:3910 (implicated_via_orthology)
Disease	Fuchs' endothelial dystrophy (is_marker_for)	CLU C3	1.17e-04	3	185	2	DOID:11555 (is_marker_for)
Disease	attention deficit hyperactivity disorder, mental or behavioural disorder	PTPRF MAD1L1	1.17e-04	3	185	2	EFO_0000677, EFO_0003888
Disease	Prostatic Neoplasms	ERCC2 ADRB2 RAB4B FAF2 PTPRK CLU MAD1L1 ARID4A IGF2R LRP2 GREB1 PRKDC CDH1	1.48e-04	616	185	13	C0033578
Disease	Malignant neoplasm of prostate	ERCC2 ADRB2 RAB4B FAF2 PTPRK CLU MAD1L1 ARID4A IGF2R LRP2 GREB1 PRKDC CDH1	1.48e-04	616	185	13	C0376358
Disease	cation-independent mannose-6-phosphate receptor measurement	MAS1 IGF2R	2.33e-04	4	185	2	EFO_0008075
Disease	alcohol use disorder (implicated_via_orthology)	EPS8 RYR2 KCNU1 DRD5 GRK6 UNC13C UNC13A	2.41e-04	195	185	7	DOID:1574 (implicated_via_orthology)
Disease	serum albumin measurement	SLC28A3 IP6K1 GCKR ADGRV1 TXNL4B MAD1L1 COL7A1 ARHGEF19 PKD1L3 MSL2 IGHG1 SBF2	3.83e-04	592	185	12	EFO_0004535
Disease	fasting blood glucose measurement, glucose tolerance test, fasting blood insulin measurement	GCKR MTNR1B	3.86e-04	5	185	2	EFO_0004307, EFO_0004465, EFO_0004466
Disease	Immunologic Deficiency Syndromes	C3 EPG5 NBAS	3.92e-04	23	185	3	C0021051
Disease	Colorectal Carcinoma	ABCC3 ERCC2 ABCA13 SLC22A15 OBSCN PROM1 ABCC1 COL7A1 SYNE1 MYO1B LRP2 CDH1 SNRNP200	5.17e-04	702	185	13	C0009402
Disease	epilepsy (implicated_via_orthology)	KCNH6 KCNU1 SLC1A4 SBF2 UNC13C UNC13A	5.89e-04	163	185	6	DOID:1826 (implicated_via_orthology)
Disease	Helicobacter Infections	PTPRZ1 CDH1	8.04e-04	7	185	2	C0079487
Disease	alpha-hydroxyisovalerate measurement	HPD GTF2H1	8.04e-04	7	185	2	EFO_0800023
Disease	metabolite measurement	ABCC3 GCKR SVOPL HPD ABCC1 GRK6 SLC7A6 SLC1A4 NBAS IGF2R MTNR1B	8.65e-04	560	185	11	EFO_0004725
Disease	glycoprotein measurement	GCKR ADGRV1 TXNL4B GRK6 PKD1L3	9.41e-04	119	185	5	EFO_0004555
Disease	serum metabolite measurement	SLC28A3 GCKR F13A1 HPD TXNL4B RIC1 ABCC1 GRK6 SLC7A6 SLC1A4 GTF2H1 IGF2R DNAH17 MTNR1B SORCS3	9.54e-04	945	185	15	EFO_0005653
Disease	attention deficit hyperactivity disorder, autism spectrum disorder, intelligence	PLK2 PTPRF CACNA1I NOVA1 HBEGF PKD1L3 MSL2 MST1R SORCS3	9.67e-04	398	185	9	EFO_0003756, EFO_0003888, EFO_0004337
Disease	melanoma	ERCC2 MELTF PTPRK CLU FAT4 UBR4 MYO1B	1.01e-03	248	185	7	C0025202
Disease	apolipoprotein B measurement	LDLRAP1 ERCC2 MAS1 GCKR ADRB1 TXNL4B NOVA2 ARHGEF19 MAN1C1 GRK6 PKD1L3 IGF2R	1.03e-03	663	185	12	EFO_0004615
Disease	heart conduction disease (implicated_via_orthology)	KCNH6 KCNU1 MMEL1	1.05e-03	32	185	3	DOID:10273 (implicated_via_orthology)
Disease	Ventricular Dysfunction	ADRB1 IGF2R	1.07e-03	8	185	2	C0242973
Disease	Malignant tumor of prostate	MAD1L1 CDH1	1.37e-03	9	185	2	cv:C0376358
Disease	Endomyocardial Fibrosis	ADRB1 IGF2R	1.37e-03	9	185	2	C0553980
Disease	birth weight, parental genotype effect measurement	MRPS22 ADRB1 NLRP13 ABCC9 MTNR1B PLCE1	1.38e-03	192	185	6	EFO_0004344, EFO_0005939
Disease	cholesteryl esters to total lipids in medium LDL percentage	GCKR TXNL4B IGF2R	1.61e-03	37	185	3	EFO_0022252
Disease	transverse temporal cortex volume measurement	P2RY1 UNC13C	1.70e-03	10	185	2	EFO_0010336
Disease	pneumonia (implicated_via_orthology)	ADRB2 C3	1.70e-03	10	185	2	DOID:552 (implicated_via_orthology)
Disease	2-aminobutyrate measurement	SLC1A4 EPG5	1.70e-03	10	185	2	EFO_0020017
Disease	hemoglobin A1 measurement	GCKR MELTF MAD1L1 DNASE1 ABCC1 RC3H2 PNKD MTNR1B CDH1 SNRNP200	1.73e-03	520	185	10	EFO_0007629
Disease	triglyceride measurement, high density lipoprotein cholesterol measurement	PLK2 SLC28A3 GCKR ADRB1 TXNL4B IGF2R P2RY1	1.78e-03	274	185	7	EFO_0004530, EFO_0004612
Disease	Drug toxicity	PLK2 CLU C3 ABCC1	1.95e-03	84	185	4	C0013221
Disease	Adverse reaction to drug	PLK2 CLU C3 ABCC1	1.95e-03	84	185	4	C0041755
Disease	Tachycardia, Ventricular	RYR2 ABCC9	2.07e-03	11	185	2	C0042514
Disease	gastric adenocarcinoma (is_implicated_in)	ABCA13 PLCE1	2.07e-03	11	185	2	DOID:3717 (is_implicated_in)
Disease	alanine measurement	GCKR SLC7A6 SLC1A4 GTF2H1	2.13e-03	86	185	4	EFO_0009765
Disease	congestive heart failure (implicated_via_orthology)	RYR2 ADRB1 ADRB2	2.17e-03	41	185	3	DOID:6000 (implicated_via_orthology)
Disease	autoimmune thyroiditis (is_implicated_in)	TG LRP2	2.48e-03	12	185	2	DOID:7188 (is_implicated_in)
Disease	cardiovascular disease	PAQR5 GCKR PHB1 ADRB1 TXNL4B MAD1L1 PNKD SORCS3 PLCE1	2.48e-03	457	185	9	EFO_0000319
Disease	triglycerides in large LDL measurement	GCKR TXNL4B IGF2R	2.49e-03	43	185	3	EFO_0022319
Disease	resting heart rate	IP6K1 GCKR KCNJ5 KLHL42 ADCK1	2.54e-03	149	185	5	EFO_0004351
Disease	fructose measurement	UBR4 P2RY1	2.91e-03	13	185	2	EFO_0010477
Disease	glutaroyl carnitine measurement	ABCC1 SLC7A6	2.91e-03	13	185	2	EFO_0021005
Disease	tRNA (guanine-N(7)-)-methyltransferase measurement	GCKR GRK6	2.91e-03	13	185	2	EFO_0802162
Disease	imidazole lactate measurement	GTF2H1 SLC38A7	2.91e-03	13	185	2	EFO_0800004
Disease	Bardet-Biedl Syndrome	IFT172 BBS10	2.91e-03	13	185	2	C0752166
Disease	glutamine measurement	GCKR F13A1 MAD1L1 GTF2H1	3.29e-03	97	185	4	EFO_0009768
Disease	triacylglycerol 52:1 measurement	SLC22A15 GCKR	3.39e-03	14	185	2	EFO_0010413
Disease	colonic neoplasm, overall survival	PAPOLA IDS	3.39e-03	14	185	2	EFO_0000638, EFO_0004288
Disease	age at last pregnancy measurement	MST1R SORCS3	3.39e-03	14	185	2	EFO_0009440
Disease	urinary bladder cancer (biomarker_via_orthology)	PHB1 CDH1	3.39e-03	14	185	2	DOID:11054 (biomarker_via_orthology)
Disease	Cardiomyopathy, Dilated	ADRB1 ADRB2 ABCC9	3.41e-03	48	185	3	C0007193
Disease	Alzheimer disease, APOE carrier status	SETX IQGAP2 MAD1L1 NBAS	3.42e-03	98	185	4	EFO_0007659, MONDO_0004975
Disease	phospholipids in medium LDL measurement	GCKR TXNL4B IGF2R	3.61e-03	49	185	3	EFO_0022183
Disease	corpus callosum volume measurement	HBEGF TG MST1R SLC38A7	3.67e-03	100	185	4	EFO_0010299
Disease	telomere length	SLC28A3 PROKR2 MAD1L1 PELI2 ELFN1 SORCS3 TNR	3.73e-03	313	185	7	EFO_0004505
Disease	Acute kidney injury	CLU C3 HBEGF LRP2	3.81e-03	101	185	4	C2609414
Disease	Acute Kidney Insufficiency	CLU C3 HBEGF LRP2	3.81e-03	101	185	4	C1565662
Disease	Kidney Failure, Acute	CLU C3 HBEGF LRP2	3.81e-03	101	185	4	C0022660
Disease	Proteinuria	LRP2 UNC13C	3.89e-03	15	185	2	HP_0000093
Disease	lysophosphatidylcholine 14:0 measurement	KBTBD8 GCKR	3.89e-03	15	185	2	EFO_0010356
Disease	parental longevity	IP6K1 TXNL4B MAD1L1 PHLPP1 PELI2 MST1R IGF2R SLC35F2 CDH1	4.14e-03	494	185	9	EFO_0007796
Disease	total lipids in LDL measurement	GCKR TXNL4B IGF2R	4.28e-03	52	185	3	EFO_0022308
Disease	triacylglycerol 50:5 measurement	GCKR MYO1B	4.43e-03	16	185	2	EFO_0010412
Disease	diacylglycerol 44:7 measurement	IFT172 GCKR	4.43e-03	16	185	2	EFO_0020069
Disease	total lipids in medium VLDL	GCKR TXNL4B IGF2R	4.76e-03	54	185	3	EFO_0022153
Disease	attention deficit hyperactivity disorder, substance abuse, antisocial behaviour measurement	RAB19 SLC28A3 RYR2 KCNU1 PTPRF PTPRK MAD1L1 ADGRL3 ARID4A ELFN1 SORCS3 PRKDC	4.82e-03	801	185	12	EFO_0003888, EFO_0007052, MONDO_0002491
Disease	remnant cholesterol measurement	GCKR TXNL4B NOVA2 IGF2R	4.83e-03	108	185	4	EFO_0010815
Disease	Antibody Deficiency Syndrome	C3 EPG5	5.00e-03	17	185	2	C0003257
Disease	glutarylcarnitine (C5-DC) measurement	ABCC1 SLC7A6	5.00e-03	17	185	2	EFO_0800030
Disease	sphingomyelin 14:0 measurement	PAPOLA GPR137B	5.00e-03	17	185	2	EFO_0010390
Disease	triacylglycerol 52:2 measurement	GCKR NOX4 TG	5.01e-03	55	185	3	EFO_0010414
Disease	serum gamma-glutamyl transferase measurement	IQGAP2 DOCK11 IFT172 SLC28A3 GCKR RYR2 TRANK1 TXNL4B C3 ARHGEF19 MYO1B PNKD PLCE1	5.22e-03	914	185	13	EFO_0004532
Disease	alcohol consumption measurement	IFT172 SLC28A3 GCKR ADGRV1 PTPRB PTPRK TXNL4B MAD1L1 CACNA1I RC3H2 ARID4A PKD1L3 MST1R NBAS MMEL1 CDH18	5.24e-03	1242	185	16	EFO_0007878
Disease	triglycerides in LDL measurement	GCKR TXNL4B IGF2R	5.27e-03	56	185	3	EFO_0022320
Disease	uric acid measurement	VPS45 KBTBD8 GCKR ADGRV1 PHB1 FAT4 FAT3 PNKD SBF2 LRP2	5.34e-03	610	185	10	EFO_0004761
Disease	total lipids in large LDL	GCKR TXNL4B IGF2R	5.53e-03	57	185	3	EFO_0022163
Disease	cholesterol in large LDL measurement	GCKR TXNL4B IGF2R	5.53e-03	57	185	3	EFO_0021901
Disease	skin aging measurement	METTL15P1 MRPS22 PLXNA1 PKD1L3 SBF2	5.79e-03	181	185	5	EFO_0008006
Disease	total cholesterol measurement, low density lipoprotein cholesterol measurement	GCKR TXNL4B NOVA2 IGF2R	5.84e-03	114	185	4	EFO_0004574, EFO_0004611
Disease	phospholipids in VLDL measurement	GCKR TXNL4B IGF2R	6.09e-03	59	185	3	EFO_0022301
Disease	insulin resistance	GCKR KCNU1 MTNR1B	6.09e-03	59	185	3	EFO_0002614
Disease	phospholipids in small LDL measurement	GCKR TXNL4B IGF2R	6.09e-03	59	185	3	EFO_0022297
Disease	Carcinoma, Granular Cell	PHB1 FAT4 HRH4 PLCE1	6.21e-03	116	185	4	C0205644
Disease	Adenocarcinoma, Tubular	PHB1 FAT4 HRH4 PLCE1	6.21e-03	116	185	4	C0205645
Disease	Adenocarcinoma, Oxyphilic	PHB1 FAT4 HRH4 PLCE1	6.21e-03	116	185	4	C0205642
Disease	Carcinoma, Cribriform	PHB1 FAT4 HRH4 PLCE1	6.21e-03	116	185	4	C0205643
Disease	Adenocarcinoma, Basal Cell	PHB1 FAT4 HRH4 PLCE1	6.21e-03	116	185	4	C0205641
Disease	Adenocarcinoma	PHB1 FAT4 HRH4 PLCE1	6.21e-03	116	185	4	C0001418
Disease	Cannabis use, age at onset	SLC28A3 RYR2	6.23e-03	19	185	2	EFO_0004847, EFO_0007585

Protein segments in the cluster

Peptide	Gene	Start	Entry
LQSLRYALSLYTQAT	UNC13A	1491	Q9UPW8
NRAYAIASSVVSFYV	ADRB1	221	P08588
SVLSRLQVESYIYAL	EPG5	386	Q9HCE0
LQVESYIYALLSSSA	EPG5	391	Q9HCE0
RAVATTAVISYDYLT	ADCK1	41	Q86TW2
NQAYAIASSIVSFYV	ADRB2	196	P07550
IRLTNLFTLTNYTYC	ELFN1	366	P0C7U0
ILNSAASYNVKTAYR	ARID4A	376	P29374
NTSLNYAAYAVKSRV	COQ3	321	Q9NZJ6
RFIYISSQLNVSSCY	GPR34	286	Q9UPC5
TAVQLYSAYEENNRT	FAT4	3746	Q6V0I7
TTNLYTQALLAYIFS	A2ML1	1131	A8K2U0
IVAVSAAVDYRSYGT	ADGRL3	981	Q9HAR2
SQVRYFTSDSQDYLI	ADGRV1	3361	Q8WXG9
QLYNVEATSYALLAL	C3	1226	P01024
YTIRTNVLYSVRTDV	ABCA13	3486	Q86UQ4
ITRSSSYQYILVRNF	ERVV-2	51	B6SEH9
RTFLQASYYVTIETG	ABCC9	366	O60706
ETLYNTAISAVVDNY	APPBP2	11	Q92624
VTYYTALHIAVLRNQ	ASB6	101	Q9NWX5
TAYSTRGNRIEISYE	BBS10	546	Q8TAM1
VSYLGRVYDLTSLAQ	CYB5D1	36	Q6P9G0
SLYNSYVESEILINA	ARMCX2	556	Q7L311
LSSVAILTDYRVVYS	NWD1	1351	Q149M9
DIAYQLSRSRNITYL	PHB1	246	P35232
SVYQTSLRERYNSLD	RC3H2	726	Q9HBD1
QERFNSITSAYYRSA	RAB12	101	Q6IQ22
TITQSYYRSAHAAII	RAB19	81	A4D1S5
NYDLTLYLVVAVATV	PCDHGA7	686	Q9Y5G6
FRSITQSYYRSANAL	RAB30	71	Q15771
LVYDITSRETYNALT	RAB4A	91	P20338
LVYDITSRETYNSLA	RAB4B	86	P61018
AVNDTLLYDSLYTRN	RIC1	791	Q4ADV7
LNRTYAISSSLISFY	DRD5	221	P21918
LYTLVQRFYAATSRQ	ABCC3	1121	O15438
SLSNIIYFSAALYRI	PAQR5	306	Q9NXK6
NVQETYRYLSDLFTT	KCNJ5	66	P48544
NSVLYQEYSDVASAR	ARHGEF19	291	Q8IW93
QLIENVSIYRISYCT	LDLRAP1	106	Q5SW96
QISAGVRYVQLSAYS	MORN1	256	Q5T089
EALRQIQYSRYTAFS	PAXIP1	781	Q6ZW49
TTLTALVRYYLQVCQ	FANCI	1171	Q9NVI1
AESSLYSCYRNVLQL	GDAP2	141	Q9NXN4
YSLGRDQVASVFYTI	OR8H2	266	Q8N162
VLANFVVDRNTISYY	OR8K5	81	Q8NH50
RVYATYQVTRGLASL	P2RY1	301	P47900
VIADNAYSSYSLIVS	PTPRB	1001	P23467
SYYTVRQLELENLTT	PTPN1	151	P18031
AITVDRYLSLYNALT	GPR6	161	P46095
NILEYSAYLAIRTAQ	HCFC2	706	Q9Y5Z7
IDITTENQYRLTSLY	MAD1L1	641	Q9Y6D9
YNTGLYLLTAISVER	MAS1	116	P04201
LLYTCYQNSQSVSRA	GREB1	406	Q4ZG55
YTVYVDSLNVSLESL	SBF2	141	Q86WG5
AGRIVVLNTNLYYTS	SMPDL3B	186	Q92485
IIQADYLYTRALTIS	FICD	156	Q9BVA6
SVVILLYSSRACYNL	GPR137C	251	Q8N3F9
LYSSRACYNLVVVTI	GPR137C	256	Q8N3F9
VSAIIQRLYSGTARY	KCNH6	511	Q9H252
RIYSCTFIQTASTQY	MTNR1B	186	P49286
ITRSSSYQYILVRNF	ERVV-1	51	B6SEH8
RSEQFVYYLTLQLDT	PLXNA1	251	Q9UIW2
RTVSYNILADTYAQT	PDE12	296	Q6L8Q7
NRYTITAYLSANITF	F13A1	546	P00488
SLTASYVRAQYQHDT	ERCC2	136	P18074
SIYSNTDANILFYVV	GLT8D2	71	Q9H1C3
RNSQNISYFESIYLV	KCNU1	256	A8MYU2
YDSVSDRIYFTQNLA	LRP2	2426	P98164
NISSLCYLYTERLTT	METTL15P1	201	P0C7V9
VLAYYTVRNFTLRNT	PTPRZ1	1861	P23471
IIDTYSARTIQNYLV	MMEL1	386	Q495T6
TQAAQYLISQRVTYE	NOVA2	466	Q9UNW9
SRYQQLAVALDSSYV	GOLGA2	161	Q08379
ATALYISASRLVLNY	MSL2	6	Q9HCI7
SVYSIAISLAQRYSV	NBAS	1681	A2RRP1
NADLSLAFQTYTIYR	NEK3	421	P51956
TLRRNDSIYEASSLY	MVB12A	196	Q96EY5
TASTYAIRVSNYDIF	NOX4	176	Q9NPH5
LIAHYYATRSAAQSV	IFT172	1536	Q9UG01
NYAYTSRVILTEANV	KBTBD8	106	Q8NFY9
QALSTYQRLYSESIL	GCKR	66	Q14397
QRTYTYQAIDTHTAR	OBSCN	6341	Q5VST9
LTYDIQSFTDTVYRQ	PAPOLA	456	P51003
SATYIAEEYSRLRSQ	MCM3	586	P25205
YVIALRSYITDNCSL	MYO15B	1426	Q96JP2
LNTSYHRQEVYVRST	ACP2	91	P11117
NFRENTYITSVSRLY	OSGIN2	191	Q9Y236
LDRESQAVYYLTLQA	CDHR2	546	Q9BYE9
YLYTANVTLSLDTVE	KLHL14	141	Q9P2G3
ALQDNYEIRYTAISV	DOCK11	1126	Q5JSL3
LISSNVSVATTYRQY	DMRT2	321	Q9Y5R5
QRVINLTDEITYSVY	DNAH17	3701	Q9UFH2
VSYTRSVTLQIYNHS	FCGBP	2126	Q9Y6R7
AVSYTRSVTLQIYNH	FCGBP	3326	Q9Y6R7
QAVSYTRSVTLQIYN	FCGBP	4526	Q9Y6R7
ATLVSYIVQILSRYD	DNASE1	41	P24855
STSIRYNLEELYQAV	CUL4A	76	Q13619
RQRYLSSSTVASYAE	CACNA1I	416	Q9P0X4
FYLNTYSNRSAIIEN	COL6A5	866	A8TX70
VLESYFQSLRTVQLY	CPNE9	386	Q8IYJ1
SIYNATVYENSAART	FAT3	46	Q8TDW7
YERTSSYQLIIQATN	FAT3	1731	Q8TDW7
ANSRITYSLYSEASV	FAT3	2631	Q8TDW7
SSSRTYQVVLGEYDR	CELA3B	76	P08861
GREAVATQLSESYYI	MAN1C1	506	Q9NR34
QVSRIAAYAYSALSQ	LAMTOR1	131	Q6IAA8
AAYAYSALSQIRVDA	LAMTOR1	136	Q6IAA8
DSTNSLVRYFINYNV	CDH18	411	Q13634
GNLTELYYARVTAVS	IL22RA1	86	Q8N6P7
VLERQASYRFYSSSL	IP6K1	321	Q92551
TVLTLAYTAYRTALS	FAM180A	126	Q6UWF9
TEYQVTVIALYANSI	COL7A1	301	Q02388
EEQYNSTYRVVSVLT	IGHG1	176	P01857
YARDSVSSVSDISQY	EPS8	51	Q12929
VTSAGVSRLVQAYYQ	EVC	781	P57679
IRQSYFASVSYLDTQ	IDS	296	P22304
ENRLYTYDHTTILAV	HBEGF	151	Q99075
VNSRFVVSLAYAYET	GRK6	241	P43250
ISAAFNIVYIYTSEL	SLC22A15	411	Q8IZD6
VQVSCYRILTSLYAL	RYR2	3126	Q92736
QTTSNTSRYAAALYR	POLR3E	106	Q9NVU0
TALYDTSVATVYVIN	CFAP74	1031	Q9C0B2
DDVNTYNAAIAYTIL	CDH1	291	P12830
YANVIAYDHSRVILT	PTPRF	1381	P10586
ITQYEISYSSIRSFD	PTPRK	521	Q15262
TQAAQYLITQRITYE	NOVA1	481	P51513
VSLARAVYSNADIYL	ABCC1	776	P33527
TVDIYIYLLSNARSV	PNPLA8	6	Q9NP80
FLLAATSVLVNYYAS	RNF139	86	Q8WU17
VTVILLYTSRACYNL	GPR137B	241	O60478
YSSLRSIVVANYEES	HPD	221	P32754
VLISYDRYLSVSNAV	HRH4	106	Q9H3N8
DRYLSVSNAVSYRTQ	HRH4	111	Q9H3N8
YLYEIQLSSITSSRN	IGF2R	2171	P11717
YIELTLQTYQEALSR	MRPS22	341	P82650
YASIFLITALSVARY	RXFP4	126	Q8TDU9
RNFSSVYAVVSALQS	RGL2	346	O15211
SQAIYLLTSRDQSYQ	ROGDI	121	Q9GZN7
LVVAVVASSVNSYYS	TOR1AIP2	226	Q8NFQ8
VLSDNYSYLIIDTQA	PNKD	126	Q8N490
YSYLIIDTQAQLAVA	PNKD	131	Q8N490
TDARVAITIYYQATE	RNF157	126	Q96PX1
SYYAVAVVRRSSHVT	MELTF	106	P08582
IAYYQALSAERLQTD	SYNE1	5896	Q8NF91
CEYRATLQRTSISQY	PLCE1	451	Q9P212
IFIQVTTSGRASYYV	SORCS3	401	Q9UPU3
DTVIFTLYNYASNQR	IQGAP2	916	Q13576
SYSLTQDRTVAVIYT	OR5AU1	316	Q8NGC0
YTLSRNQTVVVEYTH	PELI2	81	Q9HAT8
ASYVRSVYNLLNFAL	PKDREJ	1991	Q9NTG1
VNTADHRIYSYVVSR	FAF2	71	Q96CS3
LSAFSVYVNNTESYI	PROM1	406	O43490
LIQVYTGYRRSAATT	PKD1L3	746	Q7Z443
AYELSQRSLDYVAQL	SETX	1296	Q7Z333
VILAYCSQASNERTY	SLC38A7	101	Q9NVC3
TALYSLSQYHRQTEV	ARHGAP5	916	Q13017
QYISIRSEIIATYAL	SLC28A3	546	Q9HAS3
VRAYQYTTLTSVQLL	SLC35F2	126	Q8IXU6
YLLSLASVNAAVSNY	ARHGAP4	246	P98171
ISSIVNSTYYANVSA	SATB1	216	Q01826
ALVAANFNTVYIYTA	SVOPL	406	Q8N434
LYQQISYAVSRASSD	BTG4	126	Q9NY30
QYYLRVTTVASHTSD	CLU	381	P10909
LCTSVNYLRTVSLYV	PROKR1	136	Q8TCW9
NYLRTVSLYVSTNAL	PROKR1	141	Q8TCW9
YSQAVLVDRTIYISG	RIDA	21	P52758
YNLTSDIIESIFRTY	GTF2H1	186	P32780
AVRDIVNYLTAASYL	ZBTB12	96	Q9Y330
DLQSLRYALSLYTQT	UNC13C	2006	Q8NB66
RYALSLYTQTTDALI	UNC13C	2011	Q8NB66
QALTFLSSDYLSRVY	SPO11	371	Q9Y5K1
QATIDRYVVHYTSAN	TNN	821	Q9UQP3
RVDLQTANESAYAIY	TNN	1161	Q9UQP3
RTYERFTVTYTLLNN	TRAPPC14	381	Q8WVR3
LSYSSVDETQVRSLY	TASL	41	Q9HAI6
SYNVEETLTTLRYAN	KIF3B	321	O15066
SNLVVAAFRTYATDY	SLC1A4	181	P43007
YRIYSAVSAVANVND	STOML3	121	Q8TAV4
QSYISVNYSVRINET	TCN1	331	P20061
YNISVYAVISNILSL	TNR	391	Q92752
LEYAYTATLSINTEN	ZBTB44	86	Q8NCP5
VYLYVLVDSAISRNA	UPK3A	61	O75631
TYEEALTVYNLNRTT	VPS45	511	Q9NRW7
VLCASVNYLRTVSLY	PROKR2	126	Q8NFJ6
VNYLRTVSLYVSTNA	PROKR2	131	Q8NFJ6
EYSIYLLDTVNQATV	TECPR2	306	O15040
AAESSYREVVLNATY	PKHD1L1	3091	Q86WI1
ISNRYVLHANLYTSI	SUCNR1	96	Q9BXA5
VYSFSYELILQSTRL	PRKDC	646	P78527
RIASHYYITNDTVQT	SNRNP200	986	O75643
NVAYYTVLNISDVLS	SLC7A6	286	Q92536
ALYASSNELVQLDVY	PHLPP1	876	O60346
LYVALSNLDAATYQV	SLC35A3	101	Q9Y2D2
ALSRYLAASYISQSL	PLEKHG2	1276	Q9H7P9
DSNYQRCLLTSAIYA	TTC37	1156	Q6PGP7
YLLTYINEDRISTTF	PLK2	641	Q9NYY3
AAIYLVDVDQTAVYT	TXNL4B	56	Q9NX01
EIYSLFSLYQQIRSQ	TRANK1	1346	O15050
YISRYSSEQSARLLD	TSBP1	36	Q5SRN2
IDTYASFTRAYLLQN	UBR4	1166	Q5T4S7
DYAIRLAAQSTLSFY	TG	991	P01266
LVRSLNYLLYVSNFS	MST1R	476	Q04912
ATTVATERYSLLYIS	TRAV22	81	A0A0B4J277
TIYFVSSNTERSVYL	TAS2R4	66	Q9NYW5
YRITSQEISAAHSYN	KLHL42	261	Q9P2K6
VSTTLNVAQAYYARD	MYO1B	336	O43795
RYYDLQSITQTTTSL	NLRP13	441	Q86W25