Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncomplement component C1q complex binding

C4A C4B

2.84e-0410512GO:0001849
GeneOntologyMolecularFunctionbasal RNA polymerase II transcription machinery binding

BRD4 CREBBP WDR43

6.41e-0466513GO:0001099
GeneOntologyMolecularFunctionbasal transcription machinery binding

BRD4 CREBBP WDR43

6.41e-0466513GO:0001098
GeneOntologyBiologicalProcesscell cycle process

CCDC69 CDCA2 HORMAD2 DSTN MCPH1 ARHGEF10 BRD4 MKI67 GATA6 MTBP CDCA8 CREBBP KIAA0753

2.77e-0514415013GO:0022402
GeneOntologyCellularComponentsymbiont cell surface

C4A C4B

1.56e-048502GO:0106139
GeneOntologyCellularComponentother organism part

C4A C4B

2.00e-049502GO:0044217
GeneOntologyCellularComponentcondensed chromosome

HORMAD2 BRD4 MKI67 MTBP CREBBP

8.16e-04307505GO:0000793
DomainBROMODOMAIN_1

BPTF BRD4 ATAD2 CREBBP

2.38e-0637484PS00633
DomainBromodomain

BPTF BRD4 ATAD2 CREBBP

2.66e-0638484PF00439
DomainBROMODOMAIN_2

BPTF BRD4 ATAD2 CREBBP

3.63e-0641484PS50014
DomainBROMO

BPTF BRD4 ATAD2 CREBBP

4.00e-0642484SM00297
DomainBromodomain

BPTF BRD4 ATAD2 CREBBP

4.00e-0642484IPR001487
Domain-

BPTF BRD4 ATAD2 CREBBP

4.00e-06424841.20.920.10
DomainPP1-bd

CDCA2 MKI67

6.47e-062482IPR029334
DomainPP1_bind

CDCA2 MKI67

6.47e-062482PF15276
DomainBromodomain_CS

BPTF BRD4 CREBBP

3.97e-0526483IPR018359
DomainAnaphylatoxin_comp_syst

C4A C4B

6.44e-055482IPR018081
DomainAnaphylatoxn_comp_syst_dom

C4A C4B

6.44e-055482IPR001840
DomainZnf_FYVE-rel

PLEKHF2 RIMS2 FGD6

9.01e-0534483IPR017455
DomainZnf_FYVE

PLEKHF2 RIMS2 FGD6

1.26e-0438483IPR000306
DomainANATO

C4A C4B

1.35e-047482SM00104
DomainANATO

C4A C4B

1.35e-047482PF01821
DomainANAPHYLATOXIN_2

C4A C4B

1.35e-047482PS01178
DomainANAPHYLATOXIN_1

C4A C4B

1.35e-047482PS01177
DomainAnaphylatoxin/fibulin

C4A C4B

1.35e-047482IPR000020
DomainZF_FYVE

PLEKHF2 RIMS2 FGD6

1.47e-0440483PS50178
DomainThiol-ester_cl

C4A C4B

1.79e-048482PF10569
DomainMacrogloblnA2_thiol-ester-bond

C4A C4B

1.79e-048482IPR019565
DomainMacrogloblnA2_CS

C4A C4B

1.79e-048482IPR019742
DomainA2M_N

C4A C4B

2.87e-0410482PF01835
DomainA2M_N

C4A C4B

2.87e-0410482IPR002890
DomainA-macroglobulin_rcpt-bd

C4A C4B

2.87e-0410482IPR009048
DomainALPHA_2_MACROGLOBULIN

C4A C4B

2.87e-0410482PS00477
DomainA2M

C4A C4B

2.87e-0410482PF00207
DomainA2M_N_2

C4A C4B

2.87e-0410482IPR011625
DomainA2M_comp

C4A C4B

2.87e-0410482IPR011626
DomainA2M_N_2

C4A C4B

2.87e-0410482PF07703
DomainA2M_recep

C4A C4B

2.87e-0410482PF07677
DomainA2M_comp

C4A C4B

2.87e-0410482PF07678
DomainMacroglobln_a2

C4A C4B

2.87e-0410482IPR001599
DomainZnf_FYVE_PHD

BPTF PLEKHF2 RIMS2 FGD6

5.48e-04147484IPR011011
DomainRhoGEF

ARHGEF10 FGD6 PREX2

7.10e-0468483SM00325
DomainRhoGEF

ARHGEF10 FGD6 PREX2

7.73e-0470483PF00621
DomainDH_2

ARHGEF10 FGD6 PREX2

7.73e-0470483PS50010
DomainDH-domain

ARHGEF10 FGD6 PREX2

8.05e-0471483IPR000219
Domain-

ARHGEF10 FGD6 PREX2

8.05e-04714831.20.900.10
DomainC345C

C4A C4B

8.58e-0417482SM00643
DomainTerpenoid_cyclase/PrenylTrfase

C4A C4B

9.64e-0418482IPR008930
DomainNTR

C4A C4B

1.08e-0319482PF01759
DomainNetrin_module_non-TIMP

C4A C4B

1.08e-0319482IPR018933
DomainNTR

C4A C4B

1.58e-0323482PS50189
DomainNetrin_domain

C4A C4B

1.58e-0323482IPR001134
DomainTIMP-like_OB-fold

C4A C4B

2.02e-0326482IPR008993
DomainFYVE

PLEKHF2 FGD6

2.51e-0329482PF01363
DomainFYVE

PLEKHF2 FGD6

2.51e-0329482SM00064
DomainGDS_CDC24_CS

ARHGEF10 PREX2

4.51e-0339482IPR001331
PathwayREACTOME_ACTIVATION_OF_C3_AND_C5

C4A C4B

1.32e-047362MM14685
PathwayREACTOME_ACTIVATION_OF_C3_AND_C5

C4A C4B

1.76e-048362M27031
PathwayKEGG_MEDICUS_REFERENCE_CLASSICAL_PATHWAY_OF_COMPLEMENT_CASCADE_C4_C2_TO_C3_CONVERTASE_FORMATION

C4A C4B

1.76e-048362M47872
PathwayBIOCARTA_LECTIN_PATHWAY

C4A C4B

3.44e-0411362MM1430
PathwayKEGG_MEDICUS_REFERENCE_LECTIN_PATHWAY_OF_COMPLEMENT_CASCADE_C4_C2_TO_C3_CONVERTASE_FORMATION

C4A C4B

3.44e-0411362M47874
PathwayBIOCARTA_CLASSIC_PATHWAY

C4A C4B

4.12e-0412362MM1368
PathwayBIOCARTA_LECTIN_PATHWAY

C4A C4B

4.86e-0413362M4732
PathwayREACTOME_CDC42_GTPASE_CYCLE

ARHGEF10 ARHGAP39 FNBP1L PREX2

6.30e-04155364M41808
PathwayBIOCARTA_CLASSIC_PATHWAY

C4A C4B

6.52e-0415362M7146
PathwayWP_COMPLEMENT_ACTIVATION_CLASSICAL_PATHWAY

C4A C4B

8.42e-0417362MM15944
PathwayBIOCARTA_COMP_PATHWAY

C4A C4B

8.42e-0417362MM1369
PathwayREACTOME_RHOC_GTPASE_CYCLE

ARHGEF10 CCDC187 ARHGAP39

8.75e-0474363M41807
PathwayBIOCARTA_COMP_PATHWAY

C4A C4B

1.17e-0320362M917
Pubmed

A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.

SOX7 BRD4 HMX3 PROX2 MKI67 GATA6 CREBBP ZBBX RING1

8.19e-0770951922988430
Pubmed

Copy number analysis of complement C4A, C4B and C4A silencing mutation by real-time quantitative polymerase chain reaction.

C4A C4B

2.11e-06251222737222
Pubmed

Deficiency of C4 from donor or recipient mouse fails to prevent renal allograft rejection.

C4A C4B

2.11e-06251216565498
Pubmed

Complete deficiencies of complement C4A and C4B including 2-bp insertion in codon 1213 are genetic risk factors of systemic lupus erythematosus in Thai populations.

C4A C4B

2.11e-06251215998580
Pubmed

Structural polymorphism of murine C4 and its linkage to H-2.

C4A C4B

2.11e-0625127373044
Pubmed

High-throughput analysis of the C4 polymorphism by a combination of MLPA and isotype-specific ELISA's.

C4A C4B

2.11e-06251219062096
Pubmed

Ly-C: a third locus specifying alloantigens expressed only on thymocytes and lymphocytes.

CD8B CD8B2

2.11e-0625125558567
Pubmed

The chemical structure of the C4d fragment of the human complement component C4.

C4A C4B

2.11e-0625123696167
Pubmed

Restriction fragment length polymorphism of the murine C4 and Slp genes: two C4 groups.

C4A C4B

2.11e-0625121357031
Pubmed

Structural comparison of human C4A3 and C4B1 after proteolytic activation by C1s.

C4A C4B

2.11e-06251216098595
Pubmed

Activation of innate and humoral immunity in the peripheral nervous system of ALS transgenic mice.

C4A C4B

2.11e-06251219933335
Pubmed

Structural basis for the C4d.1/C4d.2 serologic allotypes of murine complement component C4.

C4A C4B

2.11e-0625122459207
Pubmed

Antigen-induced B cell apoptosis is independent of complement C4.

C4A C4B

2.11e-06251217645767
Pubmed

Cloning and modeling of CD8 beta in the amphibian ambystoma Mexicanum. Evolutionary conserved structures for interactions with major histocompatibility complex (MHC) class I molecules.

CD8B CD8B2

2.11e-06251212034498
Pubmed

Increased frequency of C4B*Q0 alleles in patients with Henoch-Schönlein purpura.

C4A C4B

2.11e-06251215787745
Pubmed

Anti-DNA autoreactivity in C4-deficient mice.

C4A C4B

2.11e-06251212207352
Pubmed

Neuropil contraction in relation to Complement C4 gene copy numbers in independent cohorts of adolescent-onset and young adult-onset schizophrenia patients-a pilot study.

C4A C4B

2.11e-06251230026462
Pubmed

A molecular map of the human major histocompatibility complex class III region linking complement genes C4, C2 and factor B.

C4A C4B

2.11e-0625126559257
Pubmed

Complement C4A and C4B Gene Copy Number Study in Alzheimer's Disease Patients.

C4A C4B

2.11e-06251227758680
Pubmed

Genetically determined partial complement C4 deficiency states are not independent risk factors for SLE in UK and Spanish populations.

C4A C4B

2.11e-06251222387014
Pubmed

Complement C4 Is Reduced in iPSC-Derived Astrocytes of Autism Spectrum Disorder Subjects.

C4A C4B

2.11e-06251234299197
Pubmed

Assessment of complement C4 gene copy number using the paralog ratio test.

C4A C4B

2.11e-06251220506482
Pubmed

Polymerase chain reaction based C4AQ0 and C4BQ0 genotyping: association with systemic lupus erythematosus in southwest Han Chinese.

C4A C4B

2.11e-06251212480675
Pubmed

Low C4, C4A and C4B gene copy numbers are stronger risk factors for juvenile-onset than for adult-onset systemic lupus erythematosus.

C4A C4B

2.11e-06251226800705
Pubmed

Complement C4 maintains peripheral B-cell tolerance in a myeloid cell dependent manner.

C4A C4B

2.11e-06251223749435
Pubmed

Copy number variations of complement component C4 are associated with Behçet's disease but not with ankylosing spondylitis associated with acute anterior uveitis.

C4A C4B

2.11e-06251223918728
Pubmed

Molecular cloning of Lyt-3, a membrane glycoprotein marking a subset of mouse T lymphocytes: molecular homology to immunoglobulin and T-cell receptor variable and joining regions.

CD8B CD8B2

2.11e-0625123035575
Pubmed

Molecular characterization of the murine cytotoxic T-cell membrane glycoprotein Ly-3 (CD8).

CD8B CD8B2

2.11e-0625123498943
Pubmed

Murine complement C4 is not required for experimental autoimmune encephalomyelitis.

C4A C4B

2.11e-06251215390104
Pubmed

Molecular genetics of androgen-dependent and -independent expression of mouse sex-limited protein.

C4A C4B

2.11e-0625123037333
Pubmed

Evidence of a role for C4 in modulating interstitial inflammation in experimental glomerulonephritis.

C4A C4B

2.11e-06251211726230
Pubmed

Quantitative variations in the expression of the mouse serum antigen Ss and its sex-limited allotype Slp.

C4A C4B

2.11e-0625124216347
Pubmed

Importance of the alpha 3-fragment of complement C4 for the binding with C4b-binding protein.

C4A C4B

2.11e-0625121699796
Pubmed

Sequence determination of the thiolester site of the fourth component of human complement.

C4A C4B

2.11e-0625126950384
Pubmed

Molecular cloning and characterization of complementary and genomic DNA clones for mouse C4 and Slp.

C4A C4B

2.11e-0625122997024
Pubmed

An immunological role for the CD8 beta-chain.

CD8B CD8B2

2.11e-0625121534146
Pubmed

Visual demonstration of the organization of the human complement C4 and 21-hydroxylase genes by high-resolution fluorescence in situ hybridization.

C4A C4B

2.11e-0625128660986
Pubmed

Constitutive expression of Slp genes in mouse strain B10.WR directed by C4 regulatory sequences.

C4A C4B

2.11e-0625123624865
Pubmed

Tissue-specific RNA processing for the complement C4 gene transcript in the H-2k mouse strain.

C4A C4B

2.11e-0625128428773
Pubmed

Determination of the loss of function complement C4 exon 29 CT insertion using a novel paralog-specific assay in healthy UK and Spanish populations.

C4A C4B

2.11e-06251221857912
Pubmed

Complement C4 deficiency--a plausible risk factor for non-tuberculous mycobacteria (NTM) infection in apparently immunocompetent patients.

C4A C4B

2.11e-06251224638111
Pubmed

Isolation of cDNA clones specifying the fourth component of mouse complement and its isotype, sex-limited protein.

C4A C4B

2.11e-0625126208559
Pubmed

The role of the histocompatibility-2-linked Ss-Slp region in the control of mouse complement.

C4A C4B

2.11e-0625124514997
Pubmed

Transcriptional repression of C4 complement by hepatitis C virus proteins.

C4A C4B

2.11e-06251221345967
Pubmed

The inheritance of susceptibility to the Gross leukemia virus in mice.

C4A C4B

2.11e-0625125919331
Pubmed

Requirement for CD8 beta chain in positive selection of CD8-lineage T cells.

CD8B CD8B2

2.11e-0625128108731
Pubmed

An ancient provirus has imposed androgen regulation on the adjacent mouse sex-limited protein gene.

C4A C4B

2.11e-0625123167981
Pubmed

Duality of the murine CD8 compartment.

CD8B CD8B2

2.11e-06251224594598
Pubmed

The dichotomous size variation of human complement C4 genes is mediated by a novel family of endogenous retroviruses, which also establishes species-specific genomic patterns among Old World primates.

C4A C4B

2.11e-0625127545960
Pubmed

Disruption of T lymphocyte positive and negative selection in mice lacking the CD8 beta chain.

CD8B CD8B2

2.11e-0625127889415
Pubmed

Murine Ly-3 restriction fragment length polymorphism and transcript size differences.

CD8B CD8B2

2.11e-0625122576243
Pubmed

AKXD recombinant inbred strains: models for studying the molecular genetic basis of murine lymphomas.

CD8B CD8B2

2.11e-0625123025647
Pubmed

Insights on the relationship between complement component C4 serum concentrations and C4 gene copy numbers in a Western Australian systemic lupus erythematosus cohort.

C4A C4B

2.11e-06251230041577
Pubmed

Restriction fragment analysis of H-2 recombinant mouse strains with crossovers between E alpha and C4 genes.

C4A C4B

2.11e-0625122572548
Pubmed

The complement component C4 of mammals.

C4A C4B

2.11e-0625122302180
Pubmed

Complete cDNA sequence of the fourth component of murine complement.

C4A C4B

2.11e-0625123862104
Pubmed

The BS variant of C4 protects against age-related loss of white matter microstructural integrity.

C4A C4B

2.11e-06251234358307
Pubmed

Gene transfer of the Ly-3 chain gene of the mouse CD8 molecular complex: co-transfer with the Ly-2 polypeptide gene results in detectable cell surface expression of the Ly-3 antigenic determinants.

CD8B CD8B2

2.11e-0625122452747
Pubmed

Acute renal allograft rejection: diagnostic significance of focal peritubular capillary C4d.

C4A C4B

2.11e-06251218360261
Pubmed

Distinct methylation states of the CD8 beta gene in peripheral T cells and intraepithelial lymphocytes.

CD8B CD8B2

2.11e-0625129233619
Pubmed

Gene CNVs and protein levels of complement C4A and C4B as novel biomarkers for partial disease remissions in new-onset type 1 diabetes patients.

C4A C4B

2.11e-06251222151770
Pubmed

C4d-positive chronic rejection: a frequent entity with a poor outcome.

C4A C4B

2.11e-06251218091514
Pubmed

Comprehensive approach to study complement C4 in systemic lupus erythematosus: Gene polymorphisms, protein levels and functional activity.

C4A C4B

2.11e-06251229080553
Pubmed

Schizophrenia risk from complex variation of complement component 4.

C4A C4B

2.11e-06251226814963
Pubmed

Genes for murine fourth complement component (C4) and sex-limited protein (Slp) identified by hybridization to C4- and Slp-specific cDNA.

C4A C4B

2.11e-0625126589636
Pubmed

C4 Deficiency is a predisposing factor for Streptococcus pneumoniae-induced autoantibody production.

C4A C4B

2.11e-06251225339671
Pubmed

A study of association of the complement C4 mutations with systemic lupus erythematosus in the Malaysian population.

C4A C4B

2.11e-06251217728371
Pubmed

N6-methyladenosine-modified circRIMS2 mediates synaptic and memory impairments by activating GluN2B ubiquitination in Alzheimer's disease.

GRIN2B RIMS2

2.11e-06251238012808
Pubmed

Stalk region of beta-chain enhances the coreceptor function of CD8.

CD8B CD8B2

2.11e-06251212847256
Pubmed

Structure and organization of the C4 genes.

C4A C4B

2.11e-0625126149580
Pubmed

Sequence heterogeneity of murine complementary DNA clones related to the C4 and C4-Slp isoforms of the fourth complement component.

C4A C4B

2.11e-0625126149581
Pubmed

The cytoplasmic domain of CD8 beta regulates Lck kinase activation and CD8 T cell development.

CD8B CD8B2

2.11e-0625129647223
Pubmed

The follicular dendritic cell restricted epitope, FDC-M2, is complement C4; localization of immune complexes in mouse tissues.

C4A C4B

2.11e-06251212115608
Pubmed

Biochemistry and biology of anaphylatoxins.

C4A C4B

2.11e-0625123542363
Pubmed

C4 from C4-high and C4-low mouse strains have identical sequences in the region corresponding to the isotype-specific segment of human C4.

C4A C4B

2.11e-0625122387317
Pubmed

Promoter elements of the mouse complement C4 gene critical for transcription activation and start site location.

C4A C4B

2.11e-0625128132550
Pubmed

Substitution of a single amino acid (aspartic acid for histidine) converts the functional activity of human complement C4B to C4A.

C4A C4B

2.11e-0625122395880
Pubmed

Effects of Complement C4 Gene Copy Number Variations, Size Dichotomy, and C4A Deficiency on Genetic Risk and Clinical Presentation of Systemic Lupus Erythematosus in East Asian Populations.

C4A C4B

2.11e-06251226814708
Pubmed

cDNA clone spanning the alpha-gamma subunit junction in the precursor of the murine fourth complement component (C4).

C4A C4B

2.11e-0625126192448
Pubmed

Complete primary structure of human C4a anaphylatoxin.

C4A C4B

2.11e-0625126167582
Pubmed

Identification of the size and antigenic determinants of the human C4 gene by a polymerase chain-reaction-based amplification method.

C4A C4B

2.11e-06251216908004
Pubmed

Slp is an essential component of an EDTA-resistant activation pathway of mouse complement.

C4A C4B

2.11e-0625121438267
Pubmed

Structural studies on the murine fourth component of complement (C4). IV. Demonstration that C4 and Slp are encoded by separate loci.

C4A C4B

2.11e-0625127365238
Pubmed

Genetic deficiency of complement isoforms C4A or C4B predicts improved survival of metastatic renal cell carcinoma.

C4A C4B

2.11e-06251219150565
Pubmed

Interaction between the labile binding sites of the fourth (C4) and fifth (C5) human complement proteins and erythrocyte cell membranes.

C4A C4B

2.11e-0625127391573
Pubmed

Elevated levels of endogenous apoptotic DNA and IFN-alpha in complement C4-deficient mice: implications for induction of systemic lupus erythematosus.

C4A C4B

2.11e-06251217506029
Pubmed

Peritubular capillary C4d deposition in lupus nephritis different from antibody-mediated renal rejection.

C4A C4B

2.11e-06251217971360
Pubmed

Low C4 gene copy numbers are associated with superior graft survival in patients transplanted with a deceased donor kidney.

C4A C4B

2.11e-06251223715124
Pubmed

Identification of the 5'-flanking regulatory region responsible for the difference in transcriptional control between mouse complement C4 and Slp genes.

C4A C4B

2.11e-0625123464002
Pubmed

Complete nucleotide and derived amino acid sequences of the fourth component of mouse complement (C4). Evolutionary aspects.

C4A C4B

2.11e-0625122993295
Pubmed

Clinical features of patients with homozygous complement C4A or C4B deficiency.

C4A C4B

2.11e-06251229928053
Pubmed

Analysis of C4 and the C4 binding protein in the MRL/lpr mouse.

C4A C4B

2.11e-06251217971229
Pubmed

The IB-peptide marker and the Ly-3 surface alloantigen: structural studies of a V kappa-region polymorphism and a T-cell marker determined by linked genes.

CD8B CD8B2

2.11e-062512408079
Pubmed

Genetic deficiency of C4 presenting with recurrent infections and a SLE-like disease. Genetic and immunologic studies.

C4A C4B

2.11e-0625126881182
Pubmed

Transcriptional diversity at the duplicated human CD8 beta loci.

CD8B CD8B2

2.11e-0625128436166
Pubmed

Identification of the site of sulfation of the fourth component of human complement.

C4A C4B

2.11e-0625123944109
Pubmed

Partial C4 deficiency in juvenile idiopathic arthritis patients.

C4A C4B

2.11e-06251217921792
Pubmed

Complement activation and complement receptors on follicular dendritic cells are critical for the function of a targeted adjuvant.

C4A C4B

2.11e-06251221880985
Pubmed

Amino acid sequence around the thiol and reactive acyl groups of human complement component C4.

C4A C4B

2.11e-0625126978711
Pubmed

Plasma Complement 3 and Complement 4 Are Promising Biomarkers for Distinguishing NMOSD From MOGAD and Are Associated With the Blood-Brain-Barrier Disruption in NMOSD.

C4A C4B

2.11e-06251235898513
InteractionH2BC8 interactions

CDCA2 BPTF BRD4 MKI67 DDX56 ATAD2 CDCA8 WDR43 EPG5 RING1

8.27e-075764810int:H2BC8
InteractionYY1 interactions

CDCA2 BPTF PLEKHF2 BRD4 MKI67 DDX56 CREBBP RING1

1.07e-05454488int:YY1
InteractionPAK1IP1 interactions

SRSF6 PLEKHF2 BRD4 WDR46 MKI67

1.70e-05135485int:PAK1IP1
InteractionRPF2 interactions

DSTN SRSF6 OTUD6B BRD4 MKI67 DDX56

1.97e-05236486int:RPF2
InteractionH3C3 interactions

CDCA2 BPTF BRD4 MKI67 ATAD2 CDCA8 WDR43 RING1

1.99e-05495488int:H3C3
InteractionNSD2 interactions

HORMAD2 SRSF6 PLEKHF2 BRD4 WDR46 MKI67

4.93e-05278486int:NSD2
InteractionWDR46 interactions

SRSF6 WDR46 MKI67 DDX56 WDR43

5.59e-05173485int:WDR46
InteractionNHLH1 interactions

CDCA2 BPTF MKI67 DDX56

5.70e-0588484int:NHLH1
InteractionDDX10 interactions

SRSF6 BRD4 WDR46 DDX56 WDR43

8.71e-05190485int:DDX10
InteractionCSNK2B interactions

SRSF6 BRD4 SEC61G CCDC187 GRIN2B ATAD2 CREBBP RING1

1.03e-04625488int:CSNK2B
InteractionE2F1 interactions

MCPH1 BRD4 ATAD2 CREBBP RING1

1.11e-04200485int:E2F1
InteractionCBX4 interactions

TRANK1 BRD4 DDX56 CREBBP RING1

1.24e-04205485int:CBX4
InteractionTTF1 interactions

SRSF6 WDR46 MKI67 GATA6

1.36e-04110484int:TTF1
InteractionRSL24D1 interactions

SRSF6 MCPH1 WDR46 MKI67

1.36e-04110484int:RSL24D1
Cytoband6p21.3

WDR46 C4A C4B RING1

1.75e-042505146p21.3
CytobandEnsembl 112 genes in cytogenetic band chr8q24

ZFAT MTBP ARHGAP39 ATAD2

6.60e-04355514chr8q24
CytobandEnsembl 112 genes in cytogenetic band chr10q26

HMX3 MKI67 ADAM12

1.60e-03207513chr10q26
CytobandEnsembl 112 genes in cytogenetic band chr8p23

SOX7 MCPH1 ARHGEF10

2.27e-03234513chr8p23
CytobandEnsembl 112 genes in cytogenetic band chr6p21

WDR46 C4A C4B RING1

2.37e-03503514chr6p21
GeneFamilyC3 and PZP like, alpha-2-macroglobulin domain containing

C4A C4B

1.30e-0493521234
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

ARHGEF10 FGD6 PREX2

2.80e-0466353722
GeneFamilyZinc fingers FYVE-type|Pleckstrin homology domain containing|Rho guanine nucleotide exchange factors

PLEKHF2 FGD6

1.63e-033135281
GeneFamilyComplement system|Sushi domain containing

C4A C4B

2.20e-0336352492
GeneFamilyGlycosyltransferase family 6|Blood group antigens

C4A C4B

2.32e-0337352454
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

CDCA2 MKI67 PREX2

5.10e-03181353694
CoexpressionGSE27241_WT_VS_RORGT_KO_TH17_POLARIZED_CD4_TCELL_UP

CDCA2 SEC61G MKI67 ATAD2 CDCA8

1.48e-05163505M8235
ToppCell10x5'-bone_marrow-Lymphocytic_T_CD4/8-lo-Cycling_T|bone_marrow / Manually curated celltypes from each tissue

CDCA2 CD8B CD8B2 MKI67 ATAD2 CDCA8

6.45e-08183516a48a6313f2f144586951cece97ec31f6d72361df
ToppCellDividing_Macrophages-Donor_08|World / lung cells shred on cell class, cell subclass, sample id

CDCA2 MKI67 MTBP ATAD2 CDCA8

1.44e-06169515eb0c993ef2eea73bc4881182520922ce9ae9368f
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CDCA2 MKI67 MTBP ATAD2 TEX52

1.66e-06174515c988471207ba06195bc3e41056435e8c31c20bbe
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SOX7 MKI67 GATA6 ATAD2 CDCA8

1.81e-0617751573ba0f0b4b33f10e9f036d6d9befa48a1258e682
ToppCelldroplet-Lung-LUNG-30m-Lymphocytic-Proliferating_NK|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDCA2 MKI67 MTBP ATAD2 CDCA8

2.07e-061825150370b395ceb9d4d66f80cf60dd8c28ac60af5c7b
ToppCell10x_3'_v3-spleen_(10x_3'_v3)-lymphocytic-T_lymphocytic-CD8-positive,_alpha-beta_T_cell|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

CDCA2 CARMIL3 MKI67 ATAD2 CDCA8

2.24e-061855159d424a8608b339dd6129c58d87626678d4ec4af7
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CDCA2 MKI67 FZD10 ATAD2 CDCA8

2.56e-0619051531de1727822e9818652946dfb962daee77ffad68
ToppCellStriatum-Macroglia-POLYDENDROCYTE|Striatum / BrainAtlas - Mouse McCarroll V32

CDCA2 SRSF6 MKI67 MTBP CDCA8

2.62e-061915156bc9c7c86040f3ebce08c350e625e345581d4550
ToppCellwk_15-18-Hematologic_Lymphocytic-T_&_ILC-Cycling_T|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

CDCA2 CD8B CD8B2 MKI67 CDCA8

2.76e-06193515bec113472c40c0106a9427248cbcf54548797596
ToppCellwk_20-22-Hematologic_Lymphocytic-T_&_ILC-Cycling_T|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

CDCA2 CD8B MKI67 ATAD2 CDCA8

2.76e-0619351581e6240cffb094b2aa3684fd0889b6497f47c4f0
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c10-MKI67-GZMK|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CDCA2 DSTN CD8B MKI67 CDCA8

2.90e-06195515be8db0a22ef8ce24819f790b0bd93670e73af76f
ToppCellCOVID-19-lung-Proliferative_fibroblast|lung / Disease (COVID-19 only), tissue and cell type

CDCA2 MKI67 ATAD2 ADAM12 CDCA8

2.98e-061965152ce8a787f2731faa913d20342d73041d59468f27
ToppCellCOVID-19-lung-Proliferative_fibroblast|COVID-19 / Disease (COVID-19 only), tissue and cell type

CDCA2 MKI67 ATAD2 ADAM12 CDCA8

2.98e-06196515ca91d5e325875e7444809b80fcbd491d8899ea36
ToppCellwk_15-18-Hematologic_Lymphocytic-B-Large_pre-B|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

CCDC69 CDCA2 MKI67 ATAD2 CDCA8

3.05e-061975157e0834b3947031bf244a10624dcf3f2095c79368
ToppCell10x5'-blood-Lymphocytic_T_CD4/8-lo-Cycling_T|blood / Manually curated celltypes from each tissue

CDCA2 CD8B MKI67 ATAD2 CDCA8

3.05e-061975151f7c3d193647b66cce6ea202a40758cd10b8bd12
ToppCell10x5'-blood-Lymphocytic_T_CD4/8-lo|blood / Manually curated celltypes from each tissue

CDCA2 CD8B MKI67 ATAD2 CDCA8

3.05e-06197515acd678586aa0e4375bc8fbcdaa1a796c8dd23885
ToppCell10x5'-GI_large-bowel-Lymphocytic_B-GC_B_(I)|GI_large-bowel / Manually curated celltypes from each tissue

CDCA2 MKI67 ATAD2 CDCA8 FGD6

3.05e-0619751580a0cfbd454409594effead7082586b06c2f411a
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c10-MKI67-GZMK|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

CDCA2 CD8B MKI67 ATAD2 CDCA8

3.21e-06199515616c04b0605907fb218263f2164c36cb2fa26b87
ToppCellSepsis-ICU-NoSEP-Lymphocyte-T/NK-T/NK_proliferative|ICU-NoSEP / Disease, condition lineage and cell class

CDCA2 CD8B MKI67 ATAD2 CDCA8

3.28e-06200515f70cc9198339eab7fbc68f5d9b75dfb28c9afc89
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c10-MKI67-GZMK|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CDCA2 CD8B MKI67 ATAD2 CDCA8

3.28e-06200515562309f9ca4a73cea5ed1d85b516891545f3ae5f
ToppCell10x_3'_v2v3-Neoplastic-Differentiated-like-AC-like-AC-like_Prolif|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CDCA2 SEC61G MKI67 ATAD2 CDCA8

3.28e-062005150de9e7412a1725a8acd51820aa3135a112ced36c
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c10-MKI67-GZMK|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CDCA2 CD8B MKI67 ATAD2 CDCA8

3.28e-0620051583cc5f7e812896d97950afbc6bdc10c4eb2f507a
ToppCellBiopsy_Control_(H.)-Immune-Proliferating_T_cells|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

CDCA2 CD8B MKI67 ATAD2 CDCA8

3.28e-06200515dd374e153106fff8a22483ba7f63b3fa3d3ab2ea
ToppCell5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-T_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CDCA2 CD8B MKI67 ATAD2 CDCA8

3.28e-062005156145bdee0d9954da7b096be4fe797066a6df2bd0
ToppCellICU-NoSEP-Lymphocyte-T_NK-T_NK_proliferative|ICU-NoSEP / Disease, Lineage and Cell Type

CDCA2 CD8B MKI67 ATAD2 CDCA8

3.28e-06200515d86119766b9c4f1570cd8045313345f9be46d431
ToppCellCOVID-19-Lymphoid-Proliferating_CD8_T_cells|COVID-19 / Condition, Lineage and Cell class

CDCA2 CD8B MKI67 ATAD2 CDCA8

3.28e-06200515b239c711cce967826432fdbd5f88eba98a88bb0c
ToppCell5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-T_cell-T_cells_proliferating|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CDCA2 CD8B MKI67 ATAD2 CDCA8

3.28e-06200515f95769e24763900eac317c6f8adbf064bae9feaf
ToppCellLPS-antiTNF-Unknown-Endothelial-Pericyte_2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CDCA2 MKI67 ADAM12 CDCA8

1.59e-0513251402491930097b75aaeedab9e8200711b0dc610944
ToppCell10x5'-blood-Lymphocytic_T_CD8-Trm_gut_CD8|blood / Manually curated celltypes from each tissue

GCNA CD8B MTBP ZC4H2

2.91e-05154514c77a02df403358361aca86c679d5c43a64ff2f7f
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CDCA2 MKI67 ATAD2 CDCA8

3.06e-05156514b3f10cd044f24807576e7d56e51df7064dbf6c50
ToppCellPND03-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ZFAT MKI67 ATAD2 CDCA8

3.14e-05157514eea53cf8d8a607264e1ee00b7a97c94bcf2ac80d
ToppCell356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1.5|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

CDCA2 CD8B CREBBP RING1

3.38e-051605148bb873704895c3b35bba8af78fedbabf7df42e71
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CDCA2 MKI67 ATAD2 CDCA8

3.63e-051635143f434015c0cbefb31eeda133c34f75384c5f7e22
ToppCellPND28-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-Treg|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HORMAD2 MKI67 MTBP CDCA8

3.72e-05164514e5258efd6765acfc394708f697ec76acaef09079
ToppCellLPS-antiTNF-Epithelial_airway-Mes-Epi-like|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CDCA2 MKI67 ADAM12 CDCA8

3.72e-051645144307b002fb41ddfc7ab8a6bca66a60942c250052
ToppCellfacs-Marrow-T-cells-24m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDCA2 DSTN MKI67 CDCA8

3.72e-051645142a230ea066decb798a0e6f2b96c7608c8e608031
ToppCellfacs-Marrow-T-cells-24m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDCA2 DSTN MKI67 CDCA8

3.72e-05164514d02d39edd0bfef5a53b814ec6d5f026d41253218
ToppCellLPS-antiTNF-Epithelial_airway-Mes-Epi-like-Airway|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CDCA2 MKI67 ADAM12 CDCA8

3.72e-051645141d84aa5b925f502ee9c5fa39714490f613a58028
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CDCA2 MKI67 ATAD2 CDCA8

3.81e-05165514eec2d327c94832d1390314c93ef6a2be4648478b
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CDCA2 MKI67 ATAD2 CDCA8

3.90e-051665142642544070564debe2deb2938d2c33997bf5ef02
ToppCell343B-Lymphocytic-CD4_T-cell-Proliferating_T_cell|343B / Donor, Lineage, Cell class and subclass (all cells)

CDCA2 MKI67 CDCA8 ZNF804A

3.99e-05167514315cde87eed2b42a1b9b068fae94caa10ec64c70
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c03-MKI67|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CDCA2 MKI67 ATAD2 CDCA8

3.99e-051675149280558baddea51aae47f3383d895a9b0c6749a4
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CDCA2 MKI67 ATAD2 CDCA8

3.99e-05167514bc132b51dec4e8f1cd2b2cd89f83641976e09292
ToppCellPND14-Immune-Immune_Myeloid-Dendritic|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MKI67 MTBP ATAD2 CDCA8

4.09e-051685149b8a74abb83c64f0b5829dcb4275f722c82b45dc
ToppCellPND14-Immune-Immune_Myeloid-Dendritic-cDC1|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MKI67 MTBP ATAD2 CDCA8

4.09e-051685144b152b8d0f4a66faf664dfacb7914b18d60ce64a
ToppCellPND14-Immune-Immune_Myeloid-Dendritic-cDC1-cDC1_G2M|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MKI67 MTBP ATAD2 CDCA8

4.09e-05168514c3169ad8f4130ef18777ed86770bb722ffb5db85
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CDCA2 MKI67 ATAD2 CDCA8

4.18e-05169514b253a4a50c06d36228fcd5d856c57202cbac158f
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_monocytic-classical_monocyte-Classical_monocytes-Classical_monocytes_L.1.2.4.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CDCA2 MKI67 ATAD2 CDCA8

4.28e-05170514cf22a843ae2d9cd6693507fed2b7c6a45abea10e
ToppCell390C-Lymphocytic-NK_cells-Proliferating_NK_cell|390C / Donor, Lineage, Cell class and subclass (all cells)

CDCA2 MKI67 ATAD2 CDCA8

4.28e-051705145319f73cff64f2bb67472c7156ee1d0f006c6fc0
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-Proliferating-cycling_ventral_progenitors|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

CDCA2 HORMAD2 MKI67 ATAD2

4.28e-0517051473601c873b177d5d134618d8e228c51381119f7d
ToppCellPND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD8_T-CD8_T_G2M|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CDCA2 CD8B MCPH1 MKI67

4.28e-05170514a0d6466e00bd3dc07f644ba3f87d5b421fd479d5
ToppCellfacs-Marrow-T_cells-18m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDCA2 DSTN MKI67 CDCA8

4.38e-0517151495e87987a2332fa646849fb0de785f1e0b8a07dd
ToppCellfacs-Marrow-T_cells-18m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDCA2 DSTN MKI67 CDCA8

4.38e-0517151436657e277aad75c4f157c1726c48e09b5836cf37
ToppCell367C-Lymphocytic-NK_cells-Proliferating_NK_cell|367C / Donor, Lineage, Cell class and subclass (all cells)

CDCA2 MKI67 ATAD2 CDCA8

4.38e-051715144ede6e916e593f208f2f8ccf82ef2335e061fc86
ToppCell367C-Myeloid-Dendritic-cDC_proliferating_2|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

CDCA2 MKI67 FNBP1L CDCA8

4.38e-051715140eea035fde32cc2a75a0d4227911edb5d54ed47e
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Epithelial-neuronal_stem_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDCA2 MKI67 ATAD2 CDCA8

4.48e-0517251435c20de4db47dbf31c857d23c7a25cd7f95c085c
ToppCellLymphoid-Lymphoid-B_cells_(cycle)|Lymphoid / shred on cell class and cell subclass (v4)

CDCA2 MKI67 MTBP CDCA8

4.48e-05172514f39822afcc35f0fbf68b8ffd1894e4b6c8d7a80c
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CDCA2 MKI67 ATAD2 CDCA8

4.48e-05172514ef33b5e0515c6d29fb6d9a673011c1b68ef264f3
ToppCell10x5'-bone_marrow-Lymphocytic_NK-Cycling_NK|bone_marrow / Manually curated celltypes from each tissue

CDCA2 MKI67 ATAD2 CDCA8

4.58e-051735148a9dd85f718564c07cf3120ad648daeb60c94fc5
ToppCell10x5'-Lung-Lymphocytic_NK-Cycling_NK|Lung / Manually curated celltypes from each tissue

CDCA2 MKI67 ATAD2 CDCA8

4.58e-05173514d815832f89f70662706620e3b03ebb1dabec0034
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CDCA2 MKI67 ATAD2 CDCA8

4.58e-05173514a25459b8140b0dbcb73e3b4cc1407b679229f25c
ToppCell5'-Adult-LargeIntestine-Hematopoietic-B_cells-Cycling_B_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CDCA2 MKI67 CDCA8 FGD6

4.58e-05173514b7e0193fd4983cb38d1bee441f608f73ee8743b9
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CDCA2 MKI67 ATAD2 CDCA8

4.69e-0517451484da9faff088d05233183b425385beb054c92d1b
ToppCellPND28-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_G2M|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MKI67 ARHGAP39 ATAD2 CDCA8

4.69e-0517451472df66319f6efbd88ecf439013d97409fbf3cb52
ToppCellPND28-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MKI67 ARHGAP39 ATAD2 CDCA8

4.69e-05174514c6087fd0e036ec7f40f0f8f17d1f6ce13ddb5235
ToppCellPND03-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_G2M|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CDCA2 MKI67 ATAD2 CDCA8

4.69e-0517451465147b0f8c2ccadd5685430d31081520c157536a
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CDCA2 MKI67 ATAD2 CDCA8

4.69e-05174514dbb4e1a6c3319ce40f81bfd2d1745a88a2cc412e
ToppCell3'-Distal_airway-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CDCA2 MKI67 ATAD2 CDCA8

4.69e-0517451446cbb462173a684ceb9e680f9259dc3b133763f7
ToppCellE18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_G2M|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

AKAP6 CDCA2 MKI67 CDCA8

4.69e-0517451441eb0a214a8b4015a26311f77061c8147144f0e7
ToppCelldroplet-Lung-18m-Hematologic-myeloid-myeloid_dendritic_cell-proliferating_dendritic|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CDCA2 MKI67 ATAD2 CDCA8

4.79e-05175514a6913f992a1ea20b43e5adeca3ede3a6fda820ad
ToppCell367C-Myeloid-Dendritic-cDC_proliferating_2|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

CDCA2 MKI67 MTBP CDCA8

4.79e-05175514bde785ff0c854646d7ab8571359e9d69a7bf013f
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)-Club_(nasal)_L.0.2.1.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CDCA2 MKI67 ATAD2 CDCA8

4.79e-051755149142ed8ca2f1c0c518deb21988221406f62fe38c
ToppCellDividing_Macrophages-IPF_03|World / lung cells shred on cell class, cell subclass, sample id

CDCA2 MKI67 CDCA8 ZNF804A

4.79e-051755140a8bf455babb3271aa00642199fb58b0b02dc3ac
ToppCellPND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_G2M|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CDCA2 MKI67 CDCA8 TEX52

4.79e-05175514ae7e0448ffd11b8908d0f6d99ff737faf5eca4bf
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling-Cycling_Distal_Convoluted_Tubule_Cell_G2M|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CDCA2 MKI67 ATAD2 CDCA8

4.79e-05175514876cea684faf42ff3eb4623ad6d7a1fb1276ee02
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c12-MKI67-TYROBP|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CDCA2 MKI67 ATAD2 CDCA8

4.79e-0517551486dfce849b2ec023a72f7e887fa681b117155e51
ToppCellStriatum-Macroglia-POLYDENDROCYTE-P5-P5_1-Sox4|Striatum / BrainAtlas - Mouse McCarroll V32

CDCA2 MKI67 ATAD2 CDCA8

4.90e-05176514d70fdc7bc48719776ed1e7c01118385e3a21623f
ToppCellStriatum-Macroglia-POLYDENDROCYTE-P5-P5_1|Striatum / BrainAtlas - Mouse McCarroll V32

CDCA2 MKI67 ATAD2 CDCA8

4.90e-05176514a84361308e5e96f3a30246cd29e109c321ee65bf
ToppCellfacs-Skin-Anagen-24m-Epithelial-actively_dividing_stem_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDCA2 MCPH1 MKI67 CDCA8

5.01e-051775148a0f0fbb06cdacb99a3fdba0da3e0494b891db4f
ToppCellfacs-Skin-Anagen-24m-Epithelial-keratinocyte_stem_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDCA2 MCPH1 MKI67 CDCA8

5.01e-05177514e9d7682517fb30fd2ad535d59779d718a7024c13
ToppCellDividing_Macrophages-Donor_05|World / lung cells shred on cell class, cell subclass, sample id

CDCA2 MKI67 ATAD2 CDCA8

5.12e-051785146557688c6790a5bcc3b9aea5b8789cf9506b3c54
ToppCellDividing_Macrophages-IPF_02|World / lung cells shred on cell class, cell subclass, sample id

CDCA2 MKI67 ATAD2 CDCA8

5.12e-051785141893fadac2ec3d5de0a641e57b7b2f962012a9ba
ToppCell10x5'-blood-Lymphocytic_NK-Cycling_NK|blood / Manually curated celltypes from each tissue

CDCA2 MKI67 ATAD2 CDCA8

5.23e-05179514c93711273055a999335ba8d0f6500e4549f46cec
ToppCell3'_v3-blood-Lymphocytic_B_plasma-Plasmablasts|blood / Manually curated celltypes from each tissue

CDCA2 ZC2HC1B MKI67 CDCA8

5.23e-051795147d3bd1f9e126a4a9e0a84720a6cc0b3d235e65ee
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CDCA2 MKI67 ATAD2 CDCA8

5.23e-0517951454191c00b29f53b520cd3243b5791daa4a2c72d7
ToppCell390C-Lymphocytic-NK_cells-Proliferating_NK_cell|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

CDCA2 MKI67 ATAD2 CDCA8

5.23e-05179514e67ad7ab04d0c1309296f57c1f53c5ca14c213fe
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_G2M|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CDCA2 MKI67 ATAD2 CDCA8

5.35e-051805145e1680088065be14447d5d5465f91f7edd071a1e
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CDCA2 MKI67 ATAD2 CDCA8

5.35e-05180514401df9cddcbca1eb8f0d2687bcacd98e95dc1493
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CDCA2 MKI67 ATAD2 CDCA8

5.35e-05180514f8a15c13d85c1bbbf86ce49bb6f86c368ddf22df
ToppCell3'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells-NK_cells_L.1.3.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CDCA2 MKI67 ATAD2 CDCA8

5.46e-05181514e4dbc09f0210de465d8347969b301c22463a2b7d
ToppCellHealthy_Control-Lymphoid-T-|Healthy_Control / Condition, Lineage, Cell class and cell subclass

CDCA2 MKI67 ATAD2 CDCA8

5.46e-05181514ac1ee313910c05b1b3cb497bae14565464919c21
ToppCellfacs-Marrow-Granulocytes-3m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDCA2 DSTN MKI67 CDCA8

5.46e-05181514566249e04dd491e6287ad2101b7b1ab11031ed8b
ToppCellfacs-Marrow-Granulocytes-3m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDCA2 DSTN MKI67 CDCA8

5.46e-05181514db9528dc7cb0230e4c36cb27da69102c588c7ee9
ToppCell10x5'-bone_marrow-Hematopoietic_progenitors-Cycling_pre-Myeloid-1|bone_marrow / Manually curated celltypes from each tissue

CDCA2 MKI67 ATAD2 CDCA8

5.46e-05181514ccd0ed30cea3fb41d34f28b3e8d80a94493bef3c
ToppCellLymphoid-Lymphoid-T_cells_(cycle)|Lymphoid / shred on cell class and cell subclass (v4)

CDCA2 MKI67 ATAD2 CDCA8

5.46e-05181514b6b41cd5d43543fe7a093033dae52a789199db0e
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling-Cycling_Connecting_Tubule_Cell_G2M|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CDCA2 MKI67 ATAD2 CDCA8

5.58e-05182514336cd05e46a741185ce3c59ee67a4b07fa6a5101
ToppCell10x5'-Liver-Lymphocytic_T_CD4/8-lo-Cycling_T|Liver / Manually curated celltypes from each tissue

CDCA2 MKI67 ATAD2 CDCA8

5.58e-0518251481557cdc88777f3bd4e1dd18a760b08fc29122ef
ToppCellfacs-Skin-Skin_Anagen-18m-Epithelial-keratinocyte_stem_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDCA2 MKI67 CDCA8 KIAA0753

5.58e-051825140fc45214f0b0766f69be6eff69cc4bec574023aa
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c12-MKI67-TYROBP|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

CDCA2 CARMIL3 WDR46 MKI67

5.70e-0518351454782c2e23bbeca5b683aa931393b1118da4aa37
ToppCelldroplet-Lung-18m-Hematologic-myeloid-classical_monocyte_proliferating|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CDCA2 MKI67 ATAD2 CDCA8

5.70e-051835146c1d7ce60e67bf1df364a4e177c351e7313eb41f
DiseaseKlatskin's tumor (is_implicated_in)

GATA6 PREX2

2.80e-055502DOID:4927 (is_implicated_in)
Diseaseadenosine measurement

AKAP6 ZNF804A

4.20e-056502EFO_0010453
Diseaseloneliness measurement

CCDC69 BPTF ADAM12 ZNF804A

5.89e-05124504EFO_0007865
DiseaseBarrett's esophagus (is_marker_for)

MKI67 GATA6

1.53e-0411502DOID:9206 (is_marker_for)
DiseaseAntibody Deficiency Syndrome

C4A EPG5

3.77e-0417502C0003257
DiseaseImmunologic Deficiency Syndromes

C4A EPG5

6.96e-0423502C0021051
DiseaseColorectal Carcinoma

AKAP6 DSTN SRSF6 MKI67 ZNF804A PREX2

1.16e-03702506C0009402
DiseaseComplement deficiency disease

C4A C4B

1.44e-0333502C0272242
Diseaseblood molybdenum measurement

AKAP6 ARHGEF10

1.90e-0338502EFO_0007582
Diseaselung cancer (is_marker_for)

SRSF6 MKI67

2.00e-0339502DOID:1324 (is_marker_for)
DiseaseGraves' disease (is_implicated_in)

C4A C4B

2.00e-0339502DOID:12361 (is_implicated_in)
Diseaseautism spectrum disorder (implicated_via_orthology)

ARHGEF10 RIMS2 CREBBP

2.20e-03152503DOID:0060041 (implicated_via_orthology)
Diseasesystemic lupus erythematosus (implicated_via_orthology)

C4A C4B

2.43e-0343502DOID:9074 (implicated_via_orthology)
Diseasedevelopmental disorder of mental health (implicated_via_orthology)

GRIN2B RING1

3.15e-0349502DOID:0060037 (implicated_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
KPQRRAKAKASRTKT

EPG5

6

Q9HCE0
KDPVSLRSKARRAKK

ARHGEF10

1311

O15013
KPKRVKSSSCKREKT

CCDC187

246

A0A096LP49
RLSCPKEKTTRKKRN

C4B

666

P0C0L5
VTSCLRKKRKPQAEK

BRD4

671

O60885
CLKKTGRPRKENKFS

CREBBP

1311

Q92793
NKKTTIEKLRCVRPS

ADAM12

741

O43184
CSTPAQLKRKIRKKS

ATAD2

1156

Q6PL18
RKCSTPEEIKKRKKA

DSTN

21

P60981
DKRKCSRSPKKIKIE

BPTF

1076

Q12830
SRLSSCKPPKKKRQE

CCDC69

6

A6NI79
TRKRKSRKPSLCQAT

ARHGAP39

491

Q9C0H5
PPKEKCKRKRSTRRS

MCPH1

366

Q8NEM0
KKPACRKKKTRTVFS

HMX3

221

A6NHT5
SECSRKKRKVSEPVK

HORMAD2

286

Q8N7B1
RVKRCPPSKKRTQSI

CDCA8

141

Q53HL2
AIKKQKRCRKIRPVS

CARMIL3

906

Q8ND23
RPHKKRKKLSSSCRK

DDX56

506

Q9NY93
RVTRSVKRCAENPKK

MKI67

3221

P46013
PDRSDKNKRRTKTVK

RIMS2

851

Q9UQ26
VSPRCPKKARERKRK

PROX2

91

Q3B8N5
PRISKAQKRREKKAA

OTUD6B

96

Q8N6M0
SRRLKKKSRRKPASV

FZD10

536

Q9ULW2
RKRKPKNINKSKTCS

GATA6

491

Q92908
KKSTLKKRVCRLPRP

CD8B2

146

A6NJW9
LRNLVKKYCPKRSSK

FNBP1L

46

Q5T0N5
KKSTLKKRVCRLPRP

CD8B

146

P10966
PCKEKKINRRKSQET

CDCA2

531

Q69YH5
AKVEKRKTRTPKCKV

GCNA

481

Q96QF7
NKECPTCRKKLVSKR

RING1

81

Q06587
TCRKKLVSKRSLRPD

RING1

86

Q06587
RLSCPKEKTTRKKRN

C4A

666

P0C0L4
CLKRRKLAKQPETVS

MTBP

481

Q96DY7
VLTKLCRKKPKARQF

PLEKHF2

41

Q9H8W4
PRRKKQAKRLCKRVD

SOX7

116

Q9BT81
RKSRSKSKSKPKSDR

SRSF6

241

Q13247
KKVKKCFSEIRSRFP

KIAA0753

381

Q2KHM9
IRPKLSLTRDKKRCN

AKAP6

1806

Q13023
REKASKRPRSQKTEK

ZFAT

166

Q9P243
KDSIRLVKRCTKPDR

SEC61G

16

P60059
LVKRCTKPDRKEFQK

SEC61G

21

P60059
SKAQASKSPARKRKR

TEX52

286

A6NCN8
KPRKTRTARLLRQKC

FGD6

316

Q6ZV73
IKDRKRKLTTFPKCF

PREX2

396

Q70Z35
KFCRIDKSRKLPHSK

WDR46

111

O15213
ICKKLFNRKRKPFSS

ZC2HC1B

36

Q5TFG8
RAFPRKKRKKPATCK

ZNF75D

331

P51815
RNTIDKQCAVRKPKK

TRANK1

1446

O15050
KRAQRTKPRKSLLCE

ZBBX

236

A8MT70
RLQAKESPQRKKRKS

WDR43

71

Q15061
TSVAPCKPKKKRRRK

ZNF804A

801

Q7Z570
CKAKSRSRNPKKPKR

ZC4H2

206

Q9NQZ6
KDSLKKRPASAKSRR

GRIN2B

1086

Q13224