Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	glycogen synthase activity, transferring glucose-1-phosphate	GYS1 GYS2	8.58e-06	2	59	2	GO:0061547
GeneOntologyMolecularFunction	alpha-1,4-glucan glucosyltransferase (UDP-glucose donor) activity	GYS1 GYS2	2.57e-05	3	59	2	GO:0004373
GeneOntologyMolecularFunction	microfilament motor activity	MYO5A MYO5B MYO7A	1.92e-04	38	59	3	GO:0000146
GeneOntologyMolecularFunction	cytoskeletal motor activity	MYO5A MYO5B CENPE MYO7A	4.10e-04	118	59	4	GO:0003774
GeneOntologyMolecularFunction	ATP-dependent activity	MYO5A MYO5B CENPE MYO7A ATP8A2 ZGRF1 NAE1 GET3	4.25e-04	614	59	8	GO:0140657
GeneOntologyMolecularFunction	UDP-glucosyltransferase activity	GYS1 GYS2	6.56e-04	13	59	2	GO:0035251
GeneOntologyMolecularFunction	D-glucose binding	GYS1 GYS2	7.63e-04	14	59	2	GO:0005536
GeneOntologyCellularComponent	Gtr1-Gtr2 GTPase complex	RRAGA RRAGB	4.68e-05	4	59	2	GO:1990131
GeneOntologyCellularComponent	early endosome	OR51E2 CLTCL1 MYO5A SNX7 NAE1 VPS8 SGK3	3.97e-04	481	59	7	GO:0005769
GeneOntologyCellularComponent	unconventional myosin complex	MYO5A MYO7A	4.24e-04	11	59	2	GO:0016461
GeneOntologyCellularComponent	myosin complex	MYO5A MYO5B MYO7A	6.21e-04	59	59	3	GO:0016459
GeneOntologyCellularComponent	HOPS complex	VPS39 VPS8	6.97e-04	14	59	2	GO:0030897
Domain	Glycogen_synth	GYS1 GYS2	9.81e-06	2	59	2	IPR008631
Domain	Glycogen_syn	GYS1 GYS2	9.81e-06	2	59	2	PF05693
Domain	Gtr1_RagA	RRAGA RRAGB	5.86e-05	4	59	2	PF04670
Domain	Gtr1_RagA	RRAGA RRAGB	5.86e-05	4	59	2	IPR006762
Domain	P-loop_NTPase	MTG1 MYO5A MYO5B CENPE MYO7A RRAGA ZGRF1 GET3 RRAGB TRIM23 EFTUD2	6.01e-05	848	59	11	IPR027417
Domain	Myosin_S1_N	MYO5A MYO5B	9.75e-05	5	59	2	IPR008989
Domain	DIL	MYO5A MYO5B	1.46e-04	6	59	2	PF01843
Domain	Dilute_dom	MYO5A MYO5B	1.46e-04	6	59	2	IPR002710
Domain	DILUTE	MYO5A MYO5B	1.46e-04	6	59	2	PS51126
Domain	DIL	MYO5A MYO5B	1.46e-04	6	59	2	SM01132
Domain	CHCR	CLTCL1 VPS39	2.04e-04	7	59	2	PS50236
Domain	Myosin_head_motor_dom	MYO5A MYO5B MYO7A	2.33e-04	38	59	3	IPR001609
Domain	MYOSIN_MOTOR	MYO5A MYO5B MYO7A	2.33e-04	38	59	3	PS51456
Domain	Myosin_head	MYO5A MYO5B MYO7A	2.33e-04	38	59	3	PF00063
Domain	MYSc	MYO5A MYO5B MYO7A	2.33e-04	38	59	3	SM00242
Domain	Clathrin_H-chain/VPS_repeat	CLTCL1 VPS39	2.71e-04	8	59	2	IPR000547
Domain	IQ	MYO5A MYO5B MYO7A	1.47e-03	71	59	3	PF00612
Domain	IQ	MYO5A MYO5B MYO7A	2.14e-03	81	59	3	SM00015
Domain	-	MTG1 MYO7A RRAGA ZGRF1 GET3 RRAGB TRIM23 EFTUD2	2.28e-03	746	59	8	3.40.50.300
Domain	IQ_motif_EF-hand-BS	MYO5A MYO5B MYO7A	2.89e-03	90	59	3	IPR000048
Domain	IQ	MYO5A MYO5B MYO7A	3.18e-03	93	59	3	PS50096
Domain	-	EGF HHIPL2	6.74e-03	39	59	2	2.120.10.30
Domain	PX	SNX7 SGK3	8.52e-03	44	59	2	SM00312
Domain	6-blade_b-propeller_TolB-like	EGF HHIPL2	9.29e-03	46	59	2	IPR011042
Pathway	WP_PROLINE_AND_HYDROXYPROLINE_PATHWAYS	PEPD PRODH	1.04e-04	5	46	2	M48327
Pathway	WP_2Q37_COPY_NUMBER_VARIATION_SYNDROME	MYO5A RRAGA GYS1 SCLY RRAGB	1.05e-04	145	46	5	M45512
Pathway	KEGG_MEDICUS_REFERENCE_GLYCOGEN_BIOSYNTHESIS	GYS1 GYS2	1.55e-04	6	46	2	M47620
Pathway	WP_INSULIN_SIGNALING	PIK3CA GYS1 GYS2 MAP3K13 SGK3	1.67e-04	160	46	5	MM15956
Pathway	WP_INSULIN_SIGNALING	PIK3CA GYS1 GYS2 MAP3K13 SGK3	1.67e-04	160	46	5	M39482
Pubmed	Identification and overlapping expression of multiple unconventional myosin genes in vertebrate cell types.	MYO5A MYO5B MYO7A	1.67e-06	14	59	3	8022818
Pubmed	Myosin Va is required for normal photoreceptor synaptic activity.	MYO5A MYO7A	2.83e-06	2	59	2	15316067
Pubmed	N6-methyladenosine modification governs liver glycogenesis by stabilizing the glycogen synthase 2 mRNA.	METTL3 GYS2	2.83e-06	2	59	2	36396934
Pubmed	Chromosomal localization of the genes encoding the kinetochore proteins CENPE and CENPF to human chromosomes 4q24-->q25 and 1q32-->q41, respectively, by fluorescence in situ hybridization.	CENPE CENPF	2.83e-06	2	59	2	7851898
Pubmed	RagA is a functional homologue of S. cerevisiae Gtr1p involved in the Ran/Gsp1-GTPase pathway.	RRAGA RRAGB	2.83e-06	2	59	2	9394008
Pubmed	Cloning of a novel family of mammalian GTP-binding proteins (RagA, RagBs, RagB1) with remote similarity to the Ras-related GTPases.	RRAGA RRAGB	2.83e-06	2	59	2	7499430
Pubmed	PRMT7 targets of Foxm1 controls alveolar myofibroblast proliferation and differentiation during alveologenesis.	CENPE CENPF PRMT7	5.18e-06	20	59	3	34497269
Pubmed	Mouse screen reveals multiple new genes underlying mouse and human hearing loss.	NECAB2 LMNB1 MYO5A MYO7A CTR9 GYS2 PEPD ARHGAP18 PRMT7 PLXNB3 CFHR4	6.69e-06	1242	59	11	30973865
Pubmed	Functional role of SGK3 in PI3K/Pten driven liver tumor development.	PIK3CA SGK3	8.48e-06	3	59	2	30975125
Pubmed	Metabolism. Differential regulation of mTORC1 by leucine and glutamine.	RRAGA RRAGB	8.48e-06	3	59	2	25567907
Pubmed	Human Rab small GTPase- and class V myosin-mediated membrane tethering in a chemically defined reconstitution system.	MYO5A MYO5B	8.48e-06	3	59	2	28939769
Pubmed	The temporal and spatial expression pattern of myosin Va, Vb and VI in the mouse ovary.	MYO5A MYO5B	8.48e-06	3	59	2	16713372
Pubmed	Role for myosin-V motor proteins in the selective delivery of Kv channel isoforms to the membrane surface of cardiac myocytes.	MYO5A MYO5B	8.48e-06	3	59	2	24508725
Pubmed	The kinetochore proteins CENP-E and CENP-F directly and specifically interact with distinct BUB mitotic checkpoint Ser/Thr kinases.	CENPE CENPF	8.48e-06	3	59	2	29748388
Pubmed	Structural insights into the globular tails of the human type v myosins Myo5a, Myo5b, And Myo5c.	MYO5A MYO5B	8.48e-06	3	59	2	24339992
Pubmed	METTL3 promotes homologous recombination repair and modulates chemotherapeutic response in breast cancer by regulating the EGF/RAD51 axis.	METTL3 EGF	8.48e-06	3	59	2	35502895
Pubmed	Myrip uses distinct domains in the cellular activation of myosin VA and myosin VIIA in melanosome transport.	MYO5A MYO7A	8.48e-06	3	59	2	19317802
Pubmed	Characterization of the kinetochore binding domain of CENP-E reveals interactions with the kinetochore proteins CENP-F and hBUBR1.	CENPE CENPF	8.48e-06	3	59	2	9763420
Pubmed	Structural insights into functional overlapping and differentiation among myosin V motors.	MYO5A MYO5B	8.48e-06	3	59	2	24097982
Pubmed	The role of Rab27a in the regulation of melanosome distribution within retinal pigment epithelial cells.	MYO5A MYO7A	8.48e-06	3	59	2	14978221
Pubmed	RagA, but not RagB, is essential for embryonic development and adult mice.	RRAGA RRAGB	8.48e-06	3	59	2	24768164
Pubmed	Nutrient mTORC1 signaling underpins regulatory T cell control of immune tolerance.	RRAGA RRAGB	8.48e-06	3	59	2	31649036
Pubmed	Rag GTPases are cardioprotective by regulating lysosomal function.	RRAGA RRAGB	8.48e-06	3	59	2	24980141
Pubmed	SGK3 mediates INPP4B-dependent PI3K signaling in breast cancer.	PIK3CA SGK3	1.69e-05	4	59	2	25458846
Pubmed	Farnesyl transferase inhibitors block the farnesylation of CENP-E and CENP-F and alter the association of CENP-E with the microtubules.	CENPE CENPF	1.69e-05	4	59	2	10852915
Pubmed	ADP-ribosylation factor 1 controls the activation of the phosphatidylinositol 3-kinase pathway to regulate epidermal growth factor-dependent growth and migration of breast cancer cells.	EGF PIK3CA	1.69e-05	4	59	2	18990689
Pubmed	Structural basis of myosin V Rab GTPase-dependent cargo recognition.	MYO5A MYO5B	1.69e-05	4	59	2	24248336
Pubmed	Vertebrate unconventional myosins.	MYO5A MYO7A	1.69e-05	4	59	2	8690736
Pubmed	Alternative splicing in class V myosins determines association with Rab10.	MYO5A MYO5B	1.69e-05	4	59	2	19008234
Pubmed	YAP plays a crucial role in the development of cardiomyopathy in lysosomal storage diseases.	RRAGA RRAGB	1.69e-05	4	59	2	33373332
Pubmed	TEIF associated centrosome activity is regulated by EGF/PI3K/Akt signaling.	EGF PIK3CA	1.69e-05	4	59	2	24769208
Pubmed	Distribution of centromeric proteins and PARP-1 during mitosis and apoptosis.	CENPE CENPF	1.69e-05	4	59	2	19723035
Pubmed	The endolysosomal adaptor PLEKHM1 is a direct target for both mTOR and MAPK pathways.	VPS39 RRAGA RRAGB	2.44e-05	33	59	3	33452816
Pubmed	Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	RBM12 VPS39 VPS8 KBTBD11	2.70e-05	101	59	4	9872452
Pubmed	The leaden gene product is required with Rab27a to recruit myosin Va to melanosomes in melanocytes.	MYO5A SGK3	2.82e-05	5	59	2	11886590
Pubmed	Assessment of myosin II, Va, VI and VIIa loss of function on endocytosis and endocytic vesicle motility in bone marrow-derived dendritic cells.	MYO5A MYO7A	2.82e-05	5	59	2	17615572
Pubmed	Slac2-c (synaptotagmin-like protein homologue lacking C2 domains-c), a novel linker protein that interacts with Rab27, myosin Va/VIIa, and actin.	MYO5A MYO7A	2.82e-05	5	59	2	12221080
Pubmed	SH3BP4 is a negative regulator of amino acid-Rag GTPase-mTORC1 signaling.	RRAGA RRAGB	2.82e-05	5	59	2	22575674
Pubmed	A high-throughput approach for measuring temporal changes in the interactome.	RBM12 LMNB1 ATG3 CTR9 NAE1 GET3 PEPD SCLY RABGAP1 RRAGB EFTUD2	2.91e-05	1455	59	11	22863883
Pubmed	A novel human nucleolar protein, Nop132, binds to the G proteins, RRAG A/C/D.	RRAGA RRAGB	4.23e-05	6	59	2	14660641
Pubmed	Alpha hydroxylation of lignoceric acid to cerebronic acid during brain development. Diminished hydroxylase activity in myelin-deficient mouse mutants.	MYO5A ATP8A2	4.23e-05	6	59	2	1150661
Pubmed	Novel G proteins, Rag C and Rag D, interact with GTP-binding proteins, Rag A and Rag B.	RRAGA RRAGB	4.23e-05	6	59	2	11073942
Pubmed	Survivin and the inner centromere protein INCENP show similar cell-cycle localization and gene knockout phenotype.	CENPE CENPF	4.23e-05	6	59	2	11084331
Pubmed	Regulation of TORC1 in response to amino acid starvation via lysosomal recruitment of TSC2.	RRAGA RRAGB	4.23e-05	6	59	2	24529380
Pubmed	Recruitment of folliculin to lysosomes supports the amino acid-dependent activation of Rag GTPases.	RRAGA RRAGB	4.23e-05	6	59	2	24081491
Pubmed	A novel positive feedback loop mediated by the docking protein Gab1 and phosphatidylinositol 3-kinase in epidermal growth factor receptor signaling.	EGF PIK3CA	4.23e-05	6	59	2	10648629
Pubmed	The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1.	RRAGA RRAGB	4.23e-05	6	59	2	18497260
Pubmed	Identification of glycogen synthase as a new substrate for stress-activated protein kinase 2b/p38beta.	GYS1 GYS2	4.23e-05	6	59	2	14680475
Pubmed	Trip6 promotes dendritic morphogenesis through dephosphorylated GRIP1-dependent myosin VI and F-actin organization.	MYO5A MYO5B	4.23e-05	6	59	2	25673849
Pubmed	Sestrins function as guanine nucleotide dissociation inhibitors for Rag GTPases to control mTORC1 signaling.	RRAGA RRAGB	5.91e-05	7	59	2	25259925
Pubmed	Role of myosin VIIa and Rab27a in the motility and localization of RPE melanosomes.	MYO5A MYO7A	5.91e-05	7	59	2	15572405
Pubmed	Hepatic glycogen synthesis in the absence of glucokinase: the case of embryonic liver.	GYS1 GYS2	5.91e-05	7	59	2	18165236
Pubmed	The ubiquitin-dependent ATPase p97 removes cytotoxic trapped PARP1 from chromatin.	LMNB1 MYO5B CTR9 GET3 PDS5A EFTUD2	6.00e-05	400	59	6	35013556
Pubmed	Integral and associated lysosomal membrane proteins.	EGF VPS39 RRAGA RRAGB	6.41e-05	126	59	4	17897319
Pubmed	Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.	RBM12 MYO5B CTR9 PLXNB3	7.23e-05	130	59	4	12421765
Pubmed	Mapping of unconventional myosins in mouse and human.	MYO5A MYO5B MYO7A	7.60e-05	48	59	3	8884266
Pubmed	Ragulator is a GEF for the rag GTPases that signal amino acid levels to mTORC1.	RRAGA RRAGB	7.87e-05	8	59	2	22980980
Pubmed	Amino acid-dependent NPRL2 interaction with Raptor determines mTOR Complex 1 activation.	RRAGA RRAGB	7.87e-05	8	59	2	26582740
Pubmed	Association of progerin-interactive partner proteins with lamina proteins: Mel18 is associated with emerin in HGPS.	EGF LMNB1	1.01e-04	9	59	2	19727227
Pubmed	Mammalian CORVET is required for fusion and conversion of distinct early endosome subpopulations.	VPS39 VPS8	1.01e-04	9	59	2	25266290
Pubmed	Amino acids activate mammalian target of rapamycin (mTOR) complex 1 without changing Rag GTPase guanyl nucleotide charging.	RRAGA RRAGB	1.01e-04	9	59	2	24337580
Pubmed	p62 is a key regulator of nutrient sensing in the mTORC1 pathway.	RRAGA RRAGB	1.01e-04	9	59	2	21981924
Pubmed	EDEM1 Drives Misfolded Protein Degradation via ERAD and Exploits ER-Phagy as Back-Up Mechanism When ERAD Is Impaired.	ATG3 VPS39 RRAGA EDEM1	1.26e-04	150	59	4	32423001
Pubmed	Characterization of the Mammalian CORVET and HOPS Complexes and Their Modular Restructuring for Endosome Specificity.	VPS39 VPS8	1.26e-04	10	59	2	26463206
Pubmed	Leucyl-tRNA synthetase is an intracellular leucine sensor for the mTORC1-signaling pathway.	RRAGA RRAGB	1.26e-04	10	59	2	22424946
Pubmed	Metabolism. Lysosomal amino acid transporter SLC38A9 signals arginine sufficiency to mTORC1.	RRAGA RRAGB	1.54e-04	11	59	2	25567906
Pubmed	Reprogramming tumour-associated macrophages to outcompete cancer cells.	RRAGA RRAGB	1.54e-04	11	59	2	37380769
Pubmed	A Tumor suppressor complex with GAP activity for the Rag GTPases that signal amino acid sufficiency to mTORC1.	RRAGA RRAGB	1.54e-04	11	59	2	23723238
Pubmed	A systematic gene-based screen of chr4q22-q32 identifies association of a novel susceptibility gene, DKK2, with the quantitative trait of alcohol dependence symptom counts.	EGF CENPE ZGRF1	1.79e-04	64	59	3	20332099
Pubmed	Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids.	RRAGA RRAGB	1.85e-04	12	59	2	20381137
Pubmed	SLC38A9 is a component of the lysosomal amino acid sensing machinery that controls mTORC1.	RRAGA RRAGB	1.85e-04	12	59	2	25561175
Pubmed	Pigmentation-related genes and their implication in malignant melanoma susceptibility.	MYO5A MYO7A	2.54e-04	14	59	2	19320733
Pubmed	The tumor suppressor Cdc73 functionally associates with CPSF and CstF 3' mRNA processing factors.	CTR9 RRAGA	2.54e-04	14	59	2	19136632
Pubmed	TBK1 Provides Context-Selective Support of the Activated AKT/mTOR Pathway in Lung Cancer.	RRAGA RRAGB	2.54e-04	14	59	2	28716898
Pubmed	Exome sequencing reveals pathogenic mutations in 91 strains of mice with Mendelian disorders.	MYO5A MYO7A ATP8A2	2.54e-04	72	59	3	25917818
Pubmed	Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.	METTL3 RBM12 ATG3 CTR9 NAE1 PDS5A RABGAP1 DPF2	3.02e-04	1014	59	8	32416067
Pubmed	Molecular characterization of the ankle-link complex in cochlear hair cells and its role in the hair bundle functioning.	ADCY4 MYO7A	3.34e-04	16	59	2	17567809
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	LMNB1 DSCAM KBTBD11 PDS5A TRIM23 PPL EFTUD2	3.36e-04	777	59	7	35844135
Pubmed	Transcriptional regulatory network of SOX4 during myoblast differentiation.	RGSL1 CTR9	4.75e-04	19	59	2	25969425
Pubmed	TRIM33 drives prostate tumor growth by stabilizing androgen receptor from Skp2-mediated degradation.	RBM12 PDS5A DPF2 EFTUD2	5.40e-04	220	59	4	35785414
Pubmed	Network organization of the huntingtin proteomic interactome in mammalian brain.	METTL3 LMNB1 MYO5A MYO5B KBTBD11 TRIM23	6.39e-04	621	59	6	22794259
Pubmed	The imprinted Phlda2 gene regulates extraembryonic energy stores.	GYS1 GYS2	6.39e-04	22	59	2	19884348
Pubmed	Phospho-tyrosine dependent protein-protein interaction network.	MTF2 PIK3CA VPS39 RABGAP1 TRDN	6.60e-04	410	59	5	25814554
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	MYO5A CENPE ZGRF1 EFTUD2	6.80e-04	234	59	4	36243803
Pubmed	A protein interaction landscape of breast cancer.	MYO5A MYO5B MTF2 PIK3CA PDS5A DPF2	7.12e-04	634	59	6	34591612
Pubmed	TRIMs and Galectins Globally Cooperate and TRIM16 and Galectin-3 Co-direct Autophagy in Endomembrane Damage Homeostasis.	RRAGB TRIM23	7.62e-04	24	59	2	27693506
Pubmed	Definition of mouse chromosome 1 and 3 gene linkage groups that are conserved on human chromosome 1: evidence that a conserved linkage group spans the centromere of human chromosome 1.	EGF CFHR4	9.66e-04	27	59	2	2574151
Pubmed	Physiogenomic comparison of edema and BMI in patients receiving rosiglitazone or pioglitazone.	PIK3CA GYS1 GYS2	1.05e-03	117	59	3	18996102
Pubmed	Histone methyltransferase DOT1L coordinates AR and MYC stability in prostate cancer.	LMNB1 MYO5A MYO5B EFTUD2	1.06e-03	264	59	4	32814769
Pubmed	Functional genomic landscape of cancer-intrinsic evasion of killing by T cells.	LMNB1 ATG3 VPS39 CTR9 GET3	1.07e-03	457	59	5	32968282
Pubmed	Characterising the dynamics of placental glycogen stores in the mouse.	GYS1 GYS2	1.12e-03	29	59	2	32798765
Pubmed	SARS-CoV-2 nucleocapsid protein binds host mRNAs and attenuates stress granules to impair host stress response.	LMNB1 VPS39 CTR9 GET3 EFTUD2	1.13e-03	463	59	5	34901782
Pubmed	Muscle developmental defects in heterogeneous nuclear Ribonucleoprotein A1 knockout mice.	MYO5A MYO5B	1.19e-03	30	59	2	28077597
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	METTL3 LMNB1 MYO5A MYO5B CENPF PPL LACTB EFTUD2	1.23e-03	1257	59	8	36526897
Pubmed	A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex.	LMNB1 ATG3 CENPF PEPD PRMT7	1.24e-03	472	59	5	38943005
Pubmed	Genetic associations of brain structural networks in schizophrenia: a preliminary study.	PIK3CA GYS2	1.27e-03	31	59	2	20691427
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	LMNB1 CENPE CENPF MYO7A PDS5A PLXNB3	1.53e-03	736	59	6	29676528
Interaction	VPS18 interactions	ATG3 VPS39 ZGRF1 VPS8 SCLY EDEM1	2.46e-06	135	58	6	int:VPS18
GeneFamily	Myosins, class V	MYO5A MYO5B	1.22e-05	3	37	2	1100
GeneFamily	Glycosyl transferases group 1 domain containing	GYS1 GYS2	1.81e-04	10	37	2	427
Coexpression	WILCOX_RESPONSE_TO_PROGESTERONE_UP	CENPF MTF2 PDS5A PPL SGK3	2.46e-05	153	59	5	M18058
Coexpression	BRUINS_UVC_RESPONSE_VIA_TP53_GROUP_A	OR51E2 NECAB2 DSCAM MYO5A MYO5B SNX7 ZGRF1 KBTBD11 PDS5A ZNF699	3.91e-05	930	59	10	MM893
Coexpression	DING_LUNG_CANCER_EXPRESSION_BY_COPY_NUMBER	PIK3CA VPS8 PEPD KBTBD11	7.73e-05	100	59	4	M14670
Coexpression	KIM_WT1_TARGETS_DN	METTL3 CENPE CENPF CTR9 DPF2 PRMT7 SGK3	8.81e-05	471	59	7	M17859
Coexpression	GSE39556_CD8A_DC_VS_NK_CELL_UP	CENPF NAE1 KBTBD11 PDS5A EDEM1	8.82e-05	200	59	5	M9406
Coexpression	GSE22103_UNSTIM_VS_GMCSF_AND_IFNG_STIM_NEUTROPHIL_DN	MTG1 DSCAM CENPE CENPF PRMT7	8.82e-05	200	59	5	M7792
Coexpression	HALLMARK_G2M_CHECKPOINT	EGF LMNB1 CENPE CENPF MTF2	8.82e-05	200	59	5	M5901
Coexpression	GSE6681_DELETED_FOXP3_VS_WT_TREG_DN	MYO7A PIK3CA PEPD PDS5A RABGAP1	8.82e-05	200	59	5	M6779
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LMNB1 CENPE CENPF ZGRF1 PLXNB3	5.30e-06	190	59	5	31de1727822e9818652946dfb962daee77ffad68
ToppCell	RV-08._Macrophage\|World / Chamber and Cluster_Paper	MYO5A CENPE CENPF ARHGAP18 ADAM28	5.58e-06	192	59	5	a1b5dc5beb97a23729b97b54fb4574d10d8fbfb3
ToppCell	E18.5-Endothelial-Endothelial_blood-vessel\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ADCY4 LMNB1 CENPE CENPF ARHGAP18	5.58e-06	192	59	5	a502e95f78f96ed060654a769c6a0cc5dc5fcfd9
ToppCell	E18.5-Endothelial\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ADCY4 LMNB1 CENPE CENPF ARHGAP18	5.58e-06	192	59	5	cb55d30880237ab8dccf7f7bd31eb7dc5aba0583
ToppCell	RV-08._Macrophage\|RV / Chamber and Cluster_Paper	MYO5A CENPE CENPF ARHGAP18 ADAM28	5.72e-06	193	59	5	12bf98a280f87e4d8f0c6887dfc855da72e47ac1
ToppCell	LPS-antiTNF-Endothelial-Endothelial-FOXM1\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	LMNB1 CENPE CENPF ZGRF1	6.47e-05	163	59	4	5285318c52aa31c9b22dc2ffff078e32e408604d
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LMNB1 CENPE CENPF ZGRF1	6.47e-05	163	59	4	3f434015c0cbefb31eeda133c34f75384c5f7e22
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LMNB1 CENPE CENPF ZGRF1	6.78e-05	165	59	4	eec2d327c94832d1390314c93ef6a2be4648478b
ToppCell	droplet-Lung-30m-Hematologic-myeloid-myeloid_dendritic_cell-myeloid_dendritic_type_1\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PEPD KBTBD11 LACTB SGK3	6.78e-05	165	59	4	479962ce1c3d6636ae62b6709635299748653801
ToppCell	PND14-Immune-Immune_Myeloid-Dendritic\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	LMNB1 CENPE CENPF RRAGB	7.27e-05	168	59	4	9b8a74abb83c64f0b5829dcb4275f722c82b45dc
ToppCell	PND14-Immune-Immune_Myeloid-Dendritic-cDC1\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	LMNB1 CENPE CENPF RRAGB	7.27e-05	168	59	4	4b152b8d0f4a66faf664dfacb7914b18d60ce64a
ToppCell	PND14-Immune-Immune_Myeloid-Dendritic-cDC1-cDC1_G2M\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	LMNB1 CENPE CENPF RRAGB	7.27e-05	168	59	4	c3169ad8f4130ef18777ed86770bb722ffb5db85
ToppCell	LPS-IL1RA+antiTNF-Endothelial-Endothelial-FOXM1\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	LMNB1 CENPE CENPF ZGRF1	7.44e-05	169	59	4	e0607af8ae8609d43e26ff2a2cab92650bfcd5b7
ToppCell	Dividing_Macrophages-IPF_04\|World / lung cells shred on cell class, cell subclass, sample id	RGSL1 LMNB1 CENPE CENPF	7.44e-05	169	59	4	bc859a103cad567caf50c3c3882d2d2017807c73
ToppCell	PND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD4_T-CD4_T_G2M\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	EGF LMNB1 CENPE CENPF	7.61e-05	170	59	4	2d5e56eee0c3ce75a9641cc14dee0e0807141c32
ToppCell	10x5'-Lung-Lymphocytic_T_CD4/8-lo-Cycling_T\|Lung / Manually curated celltypes from each tissue	LMNB1 CENPE CENPF ZGRF1	7.79e-05	171	59	4	976361f67dd725870e0513ae7a92f2dcaee17148
ToppCell	TCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocellular_Carcinoma-8\|TCGA-Liver / Sample_Type by Project: Shred V9	ADCY4 GYS2 EDEM1 CFHR4	7.79e-05	171	59	4	c4a919fe3d56ae6df2fcab6686abacc10befc053
ToppCell	droplet-Heart-HEART-1m-Endothelial-leukocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO5B ATP8A2 VPS8 KBTBD11	8.15e-05	173	59	4	9dc7746a84f0e268a7c061e1bbcd5e31903034dc
ToppCell	PND28-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_G2M\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	LMNB1 CENPE CENPF ZGRF1	8.33e-05	174	59	4	72df66319f6efbd88ecf439013d97409fbf3cb52
ToppCell	PND28-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	LMNB1 CENPE CENPF ZGRF1	8.33e-05	174	59	4	c6087fd0e036ec7f40f0f8f17d1f6ce13ddb5235
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling-Cycling_Distal_Convoluted_Tubule_Cell_G2M\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	LMNB1 CENPE CENPF ZGRF1	8.52e-05	175	59	4	876cea684faf42ff3eb4623ad6d7a1fb1276ee02
ToppCell	PBMC-Control-Myeloid-cDC-cDC-cDC_12\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	LMNB1 HHIPL2 MAP3K13 ADAM28	8.90e-05	177	59	4	cbedac0bddb8fc330a464815c905928c553b0fc0
ToppCell	PND07-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	LMNB1 MYO5B CENPE CENPF	8.90e-05	177	59	4	a68c3688f12aee22f3cb4049c4bccacbacb0fae6
ToppCell	367C-Myeloid-Dendritic-cDC_proliferating_1\|367C / Donor, Lineage, Cell class and subclass (all cells)	LMNB1 CENPE CENPF ZGRF1	8.90e-05	177	59	4	ba701d3c90722d8bff70d0fa651899305cdad257
ToppCell	PBMC-Control-Myeloid-cDC-cDC-cDC_12\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	LMNB1 HHIPL2 MAP3K13 ADAM28	9.10e-05	178	59	4	04bfecf5ea5d85c843e48d08718b5d69e7bf834e
ToppCell	PND01-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_G2M\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CENPE CENPF ATP8A2 SGK3	9.29e-05	179	59	4	df4d0b2fe47d2c7def729b3217cb01ced01495ff
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	LMNB1 CENPE CENPF ZGRF1	9.50e-05	180	59	4	401df9cddcbca1eb8f0d2687bcacd98e95dc1493
ToppCell	LPS-IL1RA-Endothelial-Endothelial-FOXM1\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	LMNB1 CENPE CENPF ZGRF1	9.50e-05	180	59	4	334e2b1f6eb7d4ece20b1c7b02107863f913237f
ToppCell	P03-Endothelial-lymphatic_endothelial_cell-endothelial_cell_of_lymphatic_vessel\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	MYO7A ATP8A2 KBTBD11 SGK3	1.01e-04	183	59	4	89727b4f65949ed2dce9d2e0228c79fe4280230c
ToppCell	10x5'v1-week_12-13-Hematopoietic-MK-MK\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	EGF GYS2 ARHGAP18 PLXNB3	1.01e-04	183	59	4	6cbc88c27dc957d182526e84824f70c8e860bf74
ToppCell	droplet-Lung-18m-Hematologic-myeloid-alveolar_macrophage-proliferating_alveolar_macrophage\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CENPE CENPF ZGRF1 PLXNB3	1.01e-04	183	59	4	e91f00b75d43ee6293fdd4a129b789cd95f8d11a
ToppCell	P03-Endothelial-lymphatic_endothelial_cell\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	MYO7A ATP8A2 KBTBD11 SGK3	1.01e-04	183	59	4	113e6d8d4bb271be984af06cd6c22b180425dcfc
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_G2M\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	LMNB1 CENPE CENPF SNX7	1.03e-04	184	59	4	d1e0e3b0eed2db8a5b7e3d6f81294667e4ba64e5
ToppCell	3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_T/NK-T_cell-T_cells_proliferating-T_cells_proliferating_L.1.1.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CENPE CENPF MYO7A APOBEC3G	1.03e-04	184	59	4	8260e688ec42a1374727bc85dceb7edd19a8b662
ToppCell	5'-GW_trimst-2-LargeIntestine-Neuronal-Glial_immature-cycling_ENCC/glia\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RGSL1 LMNB1 CENPE CENPF	1.06e-04	185	59	4	282b3de8850f3c21704339e8d8737b432a43441a
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	LMNB1 CENPE CENPF ZGRF1	1.06e-04	185	59	4	30e041d6f6e310d64809e9d6d93cd30052972f3b
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	LMNB1 CENPE CENPF ZGRF1	1.10e-04	187	59	4	e41e39fd3791acf8ae5376cc5061e196d96868ae
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	LMNB1 CENPE CENPF ZGRF1	1.10e-04	187	59	4	cefa211ef224e803ea9467882e2ca74d0b1492f1
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	LMNB1 CENPE CENPF ZGRF1	1.10e-04	187	59	4	9351fa87b69a951af85b10bf91fe9b1cce8c0517
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Epithelial-neuronal_stem_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RBM12 LMNB1 CENPE CENPF	1.10e-04	187	59	4	a2076599b33ae6750961b573bfebcb9036fa4ee8
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Epithelial-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RBM12 LMNB1 CENPE CENPF	1.10e-04	187	59	4	38ee33295a21db4aae5ba085df033db9693e41c6
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	LMNB1 CENPE CENPF ZGRF1	1.10e-04	187	59	4	057569c9437219ecc396aa6e673b1178a2273837
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Epithelial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RBM12 LMNB1 CENPE CENPF	1.10e-04	187	59	4	dbcec24d2c852964736c78e9d81650bff5c455ae
ToppCell	368C-Lymphocytic-NK_cells-Proliferating_NK_cell\|368C / Donor, Lineage, Cell class and subclass (all cells)	LMNB1 CENPE ZGRF1 APOBEC3G	1.15e-04	189	59	4	31d34bc75d4457fca197e1766922e987dbd5f8a9
ToppCell	Control-Endothelial-Endothelial-FOXM1\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	LMNB1 CENPE CENPF ZGRF1	1.15e-04	189	59	4	1e1499b062d9c647c8f38b0c4e0d871d159be5dd
ToppCell	Children_(3_yrs)-Immune-interstitial_macrophage_(C1Q_positive)-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	MYO5A MYO7A ARHGAP18 ADAM28	1.17e-04	190	59	4	2d54fca50593fbd11fe13fc2bfaf937a05db776d
ToppCell	kidney_cells-Adult_normal_reference-Immune-Lymphocytic_T/NK-Cycling_Natural_Killer_Cell_/_Natural_Killer_T_Cell-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LMNB1 CENPE CENPF APOBEC3G	1.17e-04	190	59	4	b65383e256b04122500b742caeed0b807793851e
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-immature_mesenchymal_cell-cycling_stromal\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LMNB1 CENPE CENPF RFX4	1.17e-04	190	59	4	cd37ccd30c27cf65eda0a9165f35b7672f5acaf6
ToppCell	kidney_cells-Adult_normal_reference-Immune-Lymphocytic_T/NK-Cycling_Natural_Killer_Cell_/_Natural_Killer_T_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LMNB1 CENPE CENPF APOBEC3G	1.17e-04	190	59	4	89095d3e023269d89c82e3a73550f869e3f34201
ToppCell	pdx-Tumor_cells-T1\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	LMNB1 CENPE CENPF ZGRF1	1.17e-04	190	59	4	d06ee5f89f1cec8db6897fe3b2a890a07cd3697b
ToppCell	3'_v3-GI_small-bowel-Lymphocytic_T_CD4/8-lo-Cycling_T\|GI_small-bowel / Manually curated celltypes from each tissue	LMNB1 CENPE CENPF ZGRF1	1.19e-04	191	59	4	e642fa7395c05fb53324c9d46bbc52f89fc9673f
ToppCell	E17.5-Endothelial-proliferative_endothelial_cell-proliferative_endothelial_cell\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	LMNB1 CENPE CENPF ARHGAP18	1.19e-04	191	59	4	efe0cb0b6602621f5eda72a723b83b38bf15607f
ToppCell	COVID-19-kidney-Proliferating_T_cell\|COVID-19 / Disease (COVID-19 only), tissue and cell type	LMNB1 CENPE CENPF ZGRF1	1.19e-04	191	59	4	bae388e0e9447d576e68465d73d8313ef6925ffa
ToppCell	wk_20-22-Hematologic-Myeloid-Cycling_DC\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	LMNB1 CENPE CENPF ADAM28	1.19e-04	191	59	4	1da569ebcfab4e1a95315430ae77a17a1f119263
ToppCell	E17.5-Endothelial-proliferative_endothelial_cell\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	LMNB1 CENPE CENPF ARHGAP18	1.19e-04	191	59	4	00676c598f6dae0ff9158d064248f1265432f3e1
ToppCell	droplet-Thymus-nan-3m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LMNB1 CENPE CENPF EDEM1	1.22e-04	192	59	4	041124dd5c24c1eb188d2560ba606422c0b215c5
ToppCell	tumor_Lymph_Node_/_Brain-T/NK_cells-Undetermined\|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass	LMNB1 CENPE CENPF APOBEC3G	1.22e-04	192	59	4	3856c4d611224cd6c2558631147cd5333bc0ccb7
ToppCell	droplet-Thymus-nan-3m\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LMNB1 CENPE CENPF EDEM1	1.22e-04	192	59	4	d9e61b2722aa81e4f6e11865a04f2f1e75b794ab
ToppCell	E18.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	LMNB1 CENPE CENPF ARHGAP18	1.22e-04	192	59	4	1a3f24607cb49aa610c183f4c2b7d735f484a3a4
ToppCell	E18.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	LMNB1 CENPE CENPF ARHGAP18	1.22e-04	192	59	4	c8dcd75d695d09adff083af8d5a64cf15fe027d4
ToppCell	human_hepatoblastoma-Tumor_cells-T1\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	LMNB1 CENPE CENPF ZGRF1	1.24e-04	193	59	4	4b9fa2a4424f8abe63fa7bee78db93dda04ab15f
ToppCell	Parenchymal-10x5prime-Epithelial-Epi_alveolar-Dividing_AT2\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	EGF RFX4 PPL PRODH	1.24e-04	193	59	4	44839a606ae2f8e37421bda46d588189e1c943d2
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	LMNB1 CENPE CENPF APOBEC3G	1.27e-04	194	59	4	17af04acd54dd6a895a966cbb4422de25dc4f1e6
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_cycling-mes_proliferating3_(7)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	LMNB1 CENPE CENPF ZGRF1	1.27e-04	194	59	4	f9070035553bc68106a9e0bdf4b507715a138aba
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic-lymphocyte-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	LMNB1 CENPE CENPF APOBEC3G	1.27e-04	194	59	4	3c385d93c5fe1a7817813c492f79fdb94d887357
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_myocytic-mes_proliferating_SM_(20)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	LMNB1 CENPF ZGRF1 ADAM28	1.27e-04	194	59	4	590a9d4f054e6a3685daf752c9354650fcc7d18a
ToppCell	Children_(3_yrs)-Immune-interstitial_macrophage_(C1Q_positive)-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	MYO5A MYO7A ARHGAP18 ADAM28	1.27e-04	194	59	4	663e7e7fe48157e808b4f1a0ea6ad41944e857a2
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic-lymphocyte\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	LMNB1 CENPE CENPF APOBEC3G	1.27e-04	194	59	4	635d0e88f9c542a1d9363066c6cdbc6e44db76c1
ToppCell	COVID-19-kidney-Proliferating_T_cell\|kidney / Disease (COVID-19 only), tissue and cell type	LMNB1 CENPE CENPF ZGRF1	1.29e-04	195	59	4	7e05e56f8d0a7a052830c7db12b10dace7d10760
ToppCell	COVID-19-T_cells-Cycling_NK/T_cells\|COVID-19 / group, cell type (main and fine annotations)	LMNB1 CENPE CENPF ZGRF1	1.29e-04	195	59	4	764ed100c28d9bc93ee5ecabc5291c8f184d78da
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_cycling\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	LMNB1 CENPE CENPF ZGRF1	1.29e-04	195	59	4	926eb3fc5d028be936885bea0654a77db3107234
ToppCell	E16.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_G2M\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	LMNB1 CENPE CENPF ARHGAP18	1.29e-04	195	59	4	eca24039bde02f4677f1f89a373f501c649ec2a5
ToppCell	5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells-NK_cells_L.1.3.2.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	LMNB1 CENPE CENPF APOBEC3G	1.32e-04	196	59	4	76f581e35967f8f7c85a8556129f6e8042ad11ca
ToppCell	COVID-19-lung-Proliferative_fibroblast\|lung / Disease (COVID-19 only), tissue and cell type	LMNB1 CENPE CENPF ZGRF1	1.32e-04	196	59	4	2ce8a787f2731faa913d20342d73041d59468f27
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_cycling\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	LMNB1 CENPE CENPF ZGRF1	1.32e-04	196	59	4	1d2e0b328eb822db7521b5f5724d4bd17c0bad5f
ToppCell	356C-Myeloid-Dendritic\|356C / Donor, Lineage, Cell class and subclass (all cells)	ATG3 CENPF ARHGAP18 ADAM28	1.32e-04	196	59	4	1425eb35bd170d434c47390773e5c74c30c2f592
ToppCell	COVID-19-Myeloid-Transitioning_MDM\|COVID-19 / group, cell type (main and fine annotations)	VPS8 ARHGAP18 ADAM28 SGK3	1.32e-04	196	59	4	4929cfed1f150c1fde4d79cb49895c2ea467a18f
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_cycling\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	LMNB1 CENPE CENPF ZGRF1	1.32e-04	196	59	4	73f951f7712e0aa3323676b9a4b7944d21d347c4
ToppCell	COVID-19-lung-Proliferative_fibroblast\|COVID-19 / Disease (COVID-19 only), tissue and cell type	LMNB1 CENPE CENPF ZGRF1	1.32e-04	196	59	4	ca91d5e325875e7444809b80fcbd491d8899ea36
ToppCell	T_cells-GZMK+GZMB+_T_cells\|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	LMNB1 CENPE CENPF APOBEC3G	1.32e-04	196	59	4	b237287def04def371191b054a41ec0b3150da75
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_cycling-mes_proliferating3_(7)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	LMNB1 CENPE CENPF ZGRF1	1.34e-04	197	59	4	84ed777cdba569200a3ef1654d8a12f17fcfb7f1
ToppCell	PCW_10-12-Endothelial-Endothelial_cycling-endo_proliferating2_(14)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	ADCY4 CENPE CENPF ARHGAP18	1.34e-04	197	59	4	491e12a5fca06b86443c0173f5fa750ea3b8a715
ToppCell	PCW_13-14-Endothelial-Endothelial_cycling-endo_proliferating2_(14)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	ADCY4 CENPE CENPF ARHGAP18	1.34e-04	197	59	4	8e655db7c6f04d49927a1f0a75178e5955b4af08
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_cycling\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	LMNB1 CENPE CENPF ZGRF1	1.34e-04	197	59	4	8b616cde333bdbc0c591035ad9e4949155866245
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c10-MKI67-GZMK\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	LMNB1 CENPE CENPF APOBEC3G	1.34e-04	197	59	4	17bd2aef8d8792703973643ec9743efd546b7b69
ToppCell	10x_3'_v2v3-Non-neoplastic-Lymphoid-CD4/CD8-Prolif_T-G\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	LMNB1 CENPE CENPF APOBEC3G	1.37e-04	198	59	4	beebbf637221021686e932c3d1bbf0f62cf95536
ToppCell	COVID-19_Moderate-T/NK_proliferative\|COVID-19_Moderate / disease group, cell group and cell class	LMNB1 CENPE CENPF ZGRF1	1.37e-04	198	59	4	166c000fb0e19602ffdd8bf2b2f19be2c6df96a6
ToppCell	10x_3'_v3-bone_marrow_(10x_3'_v3)-myeloid-myeloid_granulocytic-granulocyte\|bone_marrow_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	LMNB1 CENPE CENPF KBTBD11	1.37e-04	198	59	4	2e669da80363163b806f23a645474d482797ae5d
ToppCell	3'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-T_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	LMNB1 CENPE CENPF APOBEC3G	1.37e-04	198	59	4	55ea8c9d2154ded74c7b851735b24c95bae01de4
ToppCell	Caecum-B_cell-B_cell_cycling\|B_cell / Region, Cell class and subclass	CLTCL1 LMNB1 CENPE CENPF	1.37e-04	198	59	4	d2def132f3efe9305a5501a96ec82efb1f02c3f7
ToppCell	5'-GW_trimst-2-SmallIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ADCY4 LMNB1 CENPE CENPF	1.37e-04	198	59	4	604fb20ca1aaf8f07067a8e1593a30ba335891f7
ToppCell	3'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-T_cell-T_cells_proliferating\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	LMNB1 CENPE CENPF APOBEC3G	1.37e-04	198	59	4	fc7d8b8e710eedd6cfc1e5393f0c23feac283807
ToppCell	10x_5'_v1-Non-neoplastic-Lymphoid-CD4/CD8-Prolif_T-F_2\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	LMNB1 CENPE CENPF ZGRF1	1.37e-04	198	59	4	bcfe7b6d91f2e2f145cb2660b65fd2a6c1134b86
ToppCell	(0)_NK_Dividing\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	LMNB1 CENPE CENPF ZGRF1	1.37e-04	198	59	4	5ebb4965b723302152b42bfaf48bb77a57dd02c5
ToppCell	367C-Myeloid-Dendritic-cDC_proliferating_1\|Dendritic / Donor, Lineage, Cell class and subclass (all cells)	LMNB1 CENPE CENPF ZGRF1	1.40e-04	199	59	4	3d876f172487425b37b2f658dae59e0f293ee76e
ToppCell	(2)_B_cell-(24)_B_cell_cycling\|(2)_B_cell / shred on Cell_type and subtype	CLTCL1 LMNB1 CENPE CENPF	1.40e-04	199	59	4	d5a9a8a71c4de8cbcef947943f60838731bc640b
ToppCell	10x_3'_v2v3-Non-neoplastic-Lymphoid-CD4/CD8-Prolif_T\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	LMNB1 CENPE CENPF APOBEC3G	1.40e-04	199	59	4	ef767641b669eb2ef3461e51548f4dd09292de90
ToppCell	Bronchial-NucSeq-Epithelial-Epi_alveolar-Dividing_AT2\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	LMNB1 CENPE CENPF ZGRF1	1.40e-04	199	59	4	1d5a3366474c17e3df0ba5cf11b586655529e9bd
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-FOXM1\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	LMNB1 CENPE CENPF ZGRF1	1.40e-04	199	59	4	98575fcce726589e93fbb4df1aab03e57cb56076
ToppCell	LPS_IL1RA-Endothelial-Endothelial-FOXM1\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	LMNB1 CENPE CENPF ZGRF1	1.40e-04	199	59	4	be2276c9a1994579ba1d2998b49bf549c1324d44
Drug	prochloraz	ADCY4 MYO7A MTF2 GYS1 GYS2 DPF2	2.73e-06	155	58	6	CID000073665
Drug	ionomycin calcium salt; Down 200; 2uM; MCF7; HT_HG-U133A_EA	RBM12 LMNB1 CENPE PDS5A SCLY PRMT7	1.08e-05	197	58	6	882_DN
Drug	Caffeic acid [3331-39-5]; Down 200; 22.2uM; MCF7; HT_HG-U133A	METTL3 MTF2 VPS39 PDS5A EDEM1 PPL	1.11e-05	198	58	6	5352_DN
Drug	N-methylcarbamate	ATP8A2 GYS1 GYS2	1.48e-05	19	58	3	CID000030536
Drug	1-azakenpaullone	EGF GYS1 GYS2	1.48e-05	19	58	3	CID006538897
Drug	phorbol-12,13-dibenzoate	EGF GYS1 GYS2	1.73e-05	20	58	3	CID000072294
Drug	v 405	GYS1 GYS2	1.91e-05	3	58	2	CID003057126
Drug	nicotine iminium	GYS1 GYS2	1.91e-05	3	58	2	CID000000431
Drug	AC1L9HP3	CLTCL1 VPS39 VPS8 EDEM1	4.24e-05	76	58	4	CID000445265
Drug	m-anisidine	GYS1 GYS2	6.35e-05	5	58	2	CID000010824
Drug	PtdIns(3)P	CLTCL1 EGF PIK3CA VPS39 SGK3	8.35e-05	175	58	5	CID000643964
Drug	NSC406942	ADCY4 CLTCL1 EGF MYO5A MYO5B GYS1 GYS2 PRODH	8.80e-05	565	58	8	CID000001115
Drug	Pro-Leu-Ser-Arg-Thr-Leu-Ser-Val-Ala-Ala-Lys-Lys	GYS1 GYS2	9.50e-05	6	58	2	CID003277749
Drug	phenyl glucuronide	GYS1 GYS2	9.50e-05	6	58	2	CID000087235
Drug	5-chloro-indole-2-carboxylic acid	GYS1 GYS2	9.50e-05	6	58	2	CID000082693
Drug	hexanediamine	GYS1 GYS2	9.50e-05	6	58	2	CID000134940
Drug	AC1L196J	GYS1 GYS2	9.50e-05	6	58	2	CID000000415
Drug	BAY R3401	GYS1 GYS2	9.50e-05	6	58	2	CID009842599
Drug	Etoposide [33419-42-0]; Down 200; 6.8uM; MCF7; HT_HG-U133A	LMNB1 DSCAM CENPE CENPF SCLY	9.53e-05	180	58	5	5027_DN
Drug	orthovanadate	ADCY4 EGF MYO7A PIK3CA GYS1 GYS2 GET3	1.15e-04	435	58	7	CID000061672
Drug	15d-PGJ2; Down 200; 10uM; HL60; HT_HG-U133A	RBM12 CLTCL1 CENPF KBTBD11 SCLY	1.23e-04	190	58	5	1172_DN
Drug	Chloropeptide	GYS1 GYS2	1.33e-04	7	58	2	CID000025565
Drug	NSC106398	GYS1 GYS2	1.33e-04	7	58	2	CID000086763
Drug	SB415286	EGF GYS1 GYS2	1.34e-04	39	58	3	CID004210951
Drug	Flumethasone [2135-17-3]; Down 200; 9.8uM; PC3; HT_HG-U133A	LMNB1 CENPF MTF2 APOBEC3G RRAGB	1.36e-04	194	58	5	4272_DN
Drug	Azaguanine-8 [134-58-7]; Down 200; 26.2uM; MCF7; HT_HG-U133A	MYO5A VPS8 PRMT7 TRIM23 PPL	1.39e-04	195	58	5	7444_DN
Drug	Flumequine [42835-25-6]; Up 200; 15.4uM; MCF7; HT_HG-U133A	DSCAM CENPF APOBEC3G ADAM28 PRODH	1.46e-04	197	58	5	5529_UP
Drug	2-propylpentanoic acid; Down 200; 1000uM; MCF7; HT_HG-U133A	METTL3 LMNB1 ATG3 PEPD RABGAP1	1.46e-04	197	58	5	1634_DN
Drug	prochlorperazine dimaleate salt; Down 200; 10uM; PC3; HT_HG-U133A	RBM12 ATG3 CENPF APOBEC3G PRMT7	1.46e-04	197	58	5	1215_DN
Drug	estradiol, USP; Up 200; 0.1uM; MCF7; HT_HG-U133A	LMNB1 DSCAM VPS39 RRAGB PRMT7	1.49e-04	198	58	5	6968_UP
Drug	16-phenyl tetranor Prostaglandin E2; Up 200; 10uM; MCF7; HT_HG-U133A	METTL3 DSCAM ATG3 RABGAP1 TRIM23	1.49e-04	198	58	5	7541_UP
Drug	NSC226080	CLTCL1 EGF MYO5A MYO5B PIK3CA ATP8A2 GYS1 GYS2 RRAGB	1.50e-04	782	58	9	CID000005040
Drug	Mephentermine hemisulfate [1212-72-2]; Up 200; 9.4uM; PC3; HT_HG-U133A	LMNB1 APOBEC3G PDS5A RABGAP1 PRODH	1.53e-04	199	58	5	7384_UP
Drug	Luteolin [491-70-3]; Up 200; 14uM; PC3; HT_HG-U133A	ADPRH NECAB2 DSCAM RABGAP1 ADAM28	1.53e-04	199	58	5	6658_UP
Disease	estrogen-receptor positive breast cancer (is_implicated_in)	PIK3CA ADAM28	3.93e-06	2	59	2	DOID:0060075 (is_implicated_in)
Disease	Lafora disease (implicated_via_orthology)	GYS1 GYS2	2.35e-05	4	59	2	DOID:3534 (implicated_via_orthology)
Disease	Adult Hepatocellular Carcinoma	EGF PIK3CA	1.40e-04	9	59	2	C0279607
Disease	Liver carcinoma	EGF CENPE CENPF PIK3CA GYS2 KBTBD11	5.21e-04	507	59	6	C2239176
Disease	Schizophrenia	RBM12 PRODH	5.89e-04	18	59	2	cv:C0036341
Disease	Chronic myeloproliferative disorder	CENPE CENPF	6.58e-04	19	59	2	C1292778
Disease	Seckel syndrome	CENPE CENPF	8.85e-04	22	59	2	C0265202
Disease	osteoarthritis	ADPRH MYO5B VPS8 RABGAP1	1.03e-03	222	59	4	MONDO_0005178
Disease	Glycogen Storage Disease	GYS1 GYS2	1.34e-03	27	59	2	C0017919
Disease	necrotizing enterocolitis	ADCY4 ADAM28	1.34e-03	27	59	2	EFO_0003928
Disease	Prostatic Neoplasms	EGF CENPF PIK3CA PDS5A ADAM28 PPL	1.42e-03	616	59	6	C0033578
Disease	Malignant neoplasm of prostate	EGF CENPF PIK3CA PDS5A ADAM28 PPL	1.42e-03	616	59	6	C0376358

Protein segments in the cluster

Peptide	Gene	Start	Entry
IMDDCYYQGHILNEK	ADAM28	101	Q9UKQ2
HETYLCYEVERMHND	APOBEC3G	216	Q9HC16
KEAGERQIYHRYCME	GYS2	231	P54840
EHECMRIKILGDCYY	ADCY4	311	Q8NFM4
SKYMEETLCHLEYFA	ATP8A2	606	Q9NTI2
CYKRCKQMEYSDELE	ATG3	81	Q9NT62
RYEHVLEALNDYKTM	MTF2	316	Q9Y483
EADYKAALCRHKQYM	RBM12	481	Q9NTZ6
GMKEYELESLFEHYC	PEPD	216	P12955
HNLETEERMKCLYYL	PDS5A	476	Q29RF7
ALYMHYLDFCEKNDT	RFX4	81	Q33E94
LHCKFYQLERLMQEY	RABGAP1	691	Q9Y3P9
HRATYRDYDLMKANE	PPP1R2C	56	O14990
CKYLDYMQKIFHDLD	LACTB	341	P83111
IEYEYKLAQALHEMR	LMNB1	236	P20700
YHRKENLEYCIMVIG	MTG1	136	Q9BT17
DNTHALYVILYDCAM	PLXNB3	776	Q9ULL4
SYCVHQDVMKLAYAD	OR51E2	176	Q9H255
CEESHLKYMEDYHQF	PPL	311	O60437
QEMCYKAYLAIRQHA	PIK3CA	981	P42336
CKYVHYEIDACMDSE	METTL3	326	Q86U44
ECYLLAAMAYDRHAA	OR9G4	126	Q8NGQ1
HYERKLERANNLYME	MAP3K13	471	O43283
IMDKDRCYQDLHAEY	CENPF	746	P49454
HDGVCMYIEALDKYA	EGF	986	P01133
ADMLHDKDRNVKYYQ	PRMT7	36	Q9NVM4
YNLARLYEAMCEFHE	CTR9	501	Q6PD62
LYEAMCEFHEAEKLY	CTR9	506	Q6PD62
MRFKLHDTLDYECYD	CFHR4	411	Q92496
YDNELLYMAHDLAVR	EDEM1	256	Q92611
KYLDQMEDLYEDFHI	GET3	301	O43681
MEYFDLKRHELCGDY	HHIPL2	86	Q6UWX4
KEAGERQIYHRYCME	GYS1	231	P13807
FYCRDVAEMYDNILH	SGK3	361	Q96BR1
RYSEMDDHYECLNRL	CENPE	2106	Q02224
YEELARAYEHAKMEE	DSCAM	1811	O60469
EACHGLMQEYETRLY	RGSL1	206	A5PLK6
NAMYHRCLDYVLEEL	PRODH	471	O43272
FMYEREHQYDKIIDC	VPS8	911	Q8N3P4
LRDAAYCFMSDHYLE	KBTBD11	251	O94819
DMAEENIHYYEQCLA	SNX7	351	Q9UNH6
YLLAKHYQDCMEDMD	ADPRH	81	P54922
IVIHADELEELMCYY	CLTCL1	1276	P53675
CEAYEAHMRDVRDYL	SCLY	316	Q96I15
SRELEKDMHYYQSCL	RRAGA	96	Q7L523
LLGEQYYKDAMEQCH	DPF2	11	Q92785
ESRELEKDMHYYQSC	RRAGB	156	Q5VZM2
EKDMHYYQSCLEAIL	RRAGB	161	Q5VZM2
YINECDSDYHKERMI	USP9Y	861	O00507
RCLDDDTYMKDLYQL	ARHGAP18	636	Q8N392
HEQKDQYAFCRYMID	TRDN	261	Q13061
ECAEMKSTENLYYQH	ZGRF1	301	Q86YA3
LRNHMVENIYECYEE	ZNF699	156	Q32M78
YFYDLHETLCRQEEM	TRIM23	291	P36406
YLDCVMHDLRKMYSE	EFTUD2	636	Q15029
SVMVKDDYVHEFCRY	NAE1	471	Q13564
TRMAEEYCHKHYDRN	VPS39	716	Q96JC1
YILFMCVRHADYLND	MYO5A	1511	Q9Y4I1
YMCIRHADYTNDDLK	MYO5B	1506	Q9ULV0
ALDERNYHVFYCMLE	MYO7A	246	Q13402
TKELCDYFVDHMGDY	NECAB2	116	Q7Z6G3