Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionstore-operated calcium channel activity

TRPC7 TRPC3 TRPC6

9.82e-0712343GO:0015279
GeneOntologyMolecularFunctioninositol 1,4,5 trisphosphate binding

TRPC7 TRPC3 TRPC6

1.62e-0614343GO:0070679
GeneOntologyMolecularFunctionmonoatomic ion channel activity

GRID1 GRID2 SLC9C1 TRPC7 TRPC3 TRPC6 KCNJ13

1.02e-05459347GO:0005216
GeneOntologyMolecularFunctionchannel activity

GRID1 GRID2 SLC9C1 TRPC7 TRPC3 TRPC6 KCNJ13

2.42e-05525347GO:0015267
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

GRID1 GRID2 SLC9C1 TRPC7 TRPC3 TRPC6 KCNJ13

2.45e-05526347GO:0022803
GeneOntologyMolecularFunctionalcohol binding

NPC1 TRPC7 TRPC3 TRPC6

2.65e-05102344GO:0043178
GeneOntologyMolecularFunctiontransporter activity

NPC1 SLC47A1 GRID1 GRID2 SLC9C1 TRPC7 ABCA9 TRPC3 TRPC6 KCNJ13

3.81e-0512893410GO:0005215
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

SLC47A1 GRID1 GRID2 SLC9C1 TRPC7 TRPC3 TRPC6 KCNJ13

4.33e-05793348GO:0015075
GeneOntologyMolecularFunctionprotein kinase activity

AKT1 PRKCI AKT3 AKT2 PRKCZ PTK2 EPHA10

5.67e-05600347GO:0004672
GeneOntologyMolecularFunctiontransmembrane transporter activity

SLC47A1 GRID1 GRID2 SLC9C1 TRPC7 ABCA9 TRPC3 TRPC6 KCNJ13

1.16e-041180349GO:0022857
GeneOntologyMolecularFunctionestrogen response element binding

AR ESR2

1.53e-0411342GO:0034056
GeneOntologyMolecularFunctionphosphotransferase activity, alcohol group as acceptor

AKT1 PRKCI AKT3 AKT2 PRKCZ PTK2 EPHA10

1.61e-04709347GO:0016773
GeneOntologyMolecularFunctionprotein kinase C binding

AKT1 AKT3 AKT2

1.92e-0466343GO:0005080
GeneOntologyMolecularFunctionkinase activity

AKT1 PRKCI AKT3 AKT2 PRKCZ PTK2 EPHA10

2.54e-04764347GO:0016301
GeneOntologyMolecularFunctionligand-gated monoatomic ion channel activity

GRID1 GRID2 TRPC3 KCNJ13

3.13e-04193344GO:0015276
GeneOntologyMolecularFunctiondiacylglycerol-dependent serine/threonine kinase activity

PRKCI PRKCZ

3.33e-0416342GO:0004697
GeneOntologyMolecularFunctionligand-gated channel activity

GRID1 GRID2 TRPC3 KCNJ13

3.38e-04197344GO:0022834
GeneOntologyMolecularFunctionprotein serine kinase activity

AKT1 PRKCI AKT3 AKT2 PRKCZ

3.48e-04363345GO:0106310
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

SLC47A1 SLC9C1 TRPC7 TRPC3 TRPC6 KCNJ13

5.94e-04627346GO:0022890
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

SLC47A1 SLC9C1 TRPC7 TRPC3 TRPC6 KCNJ13

8.03e-04664346GO:0008324
GeneOntologyMolecularFunctiontransferase activity, transferring phosphorus-containing groups

AKT1 PRKCI AKT3 AKT2 PRKCZ PTK2 EPHA10

8.72e-04938347GO:0016772
GeneOntologyMolecularFunctionprotein serine/threonine kinase activity

AKT1 PRKCI AKT3 AKT2 PRKCZ

8.86e-04446345GO:0004674
GeneOntologyMolecularFunctionglutamate receptor activity

GRID1 GRID2

9.62e-0427342GO:0008066
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

SLC9C1 TRPC7 TRPC3 TRPC6 KCNJ13

1.07e-03465345GO:0046873
GeneOntologyMolecularFunctioncalcium channel activity

TRPC7 TRPC3 TRPC6

1.36e-03129343GO:0005262
GeneOntologyMolecularFunctionsteroid binding

NPC1 AR ESR2

1.49e-03133343GO:0005496
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

SLC47A1 SLC9C1 TRPC7 TRPC3 TRPC6 KCNJ13

1.59e-03758346GO:0015318
GeneOntologyMolecularFunctioncalcium ion transmembrane transporter activity

TRPC7 TRPC3 TRPC6

2.14e-03151343GO:0015085
GeneOntologyMolecularFunction14-3-3 protein binding

AKT1 PRKCZ

2.32e-0342342GO:0071889
GeneOntologyMolecularFunctiongated channel activity

GRID1 GRID2 TRPC3 KCNJ13

2.40e-03334344GO:0022836
GeneOntologyMolecularFunctionmonoatomic cation channel activity

TRPC7 TRPC3 TRPC6 KCNJ13

2.64e-03343344GO:0005261
GeneOntologyMolecularFunctionpotassium channel regulator activity

AKT1 PRKCZ

4.24e-0357342GO:0015459
GeneOntologyMolecularFunctiontransmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential

GRID1 GRID2

4.24e-0357342GO:1904315
GeneOntologyMolecularFunctionnuclear receptor activity

AR ESR2

4.68e-0360342GO:0004879
GeneOntologyMolecularFunctionneurotransmitter receptor activity involved in regulation of postsynaptic membrane potential

GRID1 GRID2

4.68e-0360342GO:0099529
GeneOntologyMolecularFunctionligand-activated transcription factor activity

AR ESR2

4.84e-0361342GO:0098531
GeneOntologyMolecularFunctiongeneral transcription initiation factor binding

BTAF1 AR

5.31e-0364342GO:0140296
GeneOntologyMolecularFunctiontransmitter-gated channel activity

GRID1 GRID2

5.47e-0365342GO:0022835
GeneOntologyMolecularFunctiontransmitter-gated monoatomic ion channel activity

GRID1 GRID2

5.47e-0365342GO:0022824
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

NPC1 TAS2R42 GRID1 GRID2 OR10H3 AR EPHA10

6.89e-031353347GO:0004888
GeneOntologyMolecularFunctionpostsynaptic neurotransmitter receptor activity

GRID1 GRID2

7.22e-0375342GO:0098960
GeneOntologyMolecularFunctionextracellular ligand-gated monoatomic ion channel activity

GRID1 GRID2

7.60e-0377342GO:0005230
GeneOntologyMolecularFunctionvirus receptor activity

NPC1 RPSA

9.20e-0385342GO:0001618
GeneOntologyMolecularFunctionexogenous protein binding

NPC1 RPSA

9.41e-0386342GO:0140272
GeneOntologyMolecularFunctionneurotransmitter receptor activity

GRID1 GRID2

1.26e-02100342GO:0030594
GeneOntologyBiologicalProcessmonoatomic ion transport

SLC47A1 GRID1 GRID2 AKT1 AKT3 AKT2 SLC9C1 TRPC7 ZMPSTE24 TRPC3 TRPC6 KCNJ13

6.94e-0713743312GO:0006811
GeneOntologyBiologicalProcesscellular response to hormone stimulus

NPC1 AKT1 PRKCI AKT3 AKT2 PRKCZ AR PTK2 ESR2

1.44e-06727339GO:0032870
GeneOntologyBiologicalProcessmonoatomic cation transport

SLC47A1 AKT1 AKT3 AKT2 SLC9C1 TRPC7 ZMPSTE24 TRPC3 TRPC6 KCNJ13

8.39e-0611573310GO:0006812
GeneOntologyBiologicalProcessnegative regulation of long-chain fatty acid import across plasma membrane

AKT1 AKT2

1.49e-054332GO:0010748
GeneOntologyBiologicalProcessnegative regulation of long-chain fatty acid import into cell

AKT1 AKT2

1.49e-054332GO:0140213
GeneOntologyBiologicalProcessmetal ion transport

AKT1 AKT3 AKT2 SLC9C1 TRPC7 ZMPSTE24 TRPC3 TRPC6 KCNJ13

1.92e-051000339GO:0030001
GeneOntologyBiologicalProcessgland development

AACS NPC1 AKT1 AKT2 ZMPSTE24 AR ESR2

2.37e-05558337GO:0048732
GeneOntologyBiologicalProcessresponse to hormone

NPC1 AKT1 PRKCI AKT3 AKT2 PRKCZ AR PTK2 ESR2

2.66e-051042339GO:0009725
GeneOntologyBiologicalProcesscellular response to peptide hormone stimulus

AKT1 PRKCI AKT3 AKT2 PRKCZ PTK2

2.77e-05381336GO:0071375
GeneOntologyBiologicalProcessimport across plasma membrane

SLC47A1 AKT1 AKT2 SLC9C1 KCNJ13

3.04e-05230335GO:0098739
GeneOntologyBiologicalProcessregulation of protein localization to membrane

AKT1 PRKCI AKT2 PRKCZ AR

3.50e-05237335GO:1905475
GeneOntologyBiologicalProcesspositive regulation of transport

AACS AKT1 PRKCI AKT3 AKT2 PRKCZ PTK2 TRPC3 TRPC6

3.55e-051081339GO:0051050
GeneOntologyBiologicalProcesspositive regulation of sodium ion transport

AKT1 AKT3 AKT2

4.10e-0542333GO:0010765
GeneOntologyBiologicalProcessmonoatomic ion transmembrane transport

SLC47A1 GRID1 GRID2 AKT1 SLC9C1 TRPC7 TRPC3 TRPC6 KCNJ13

4.53e-051115339GO:0034220
GeneOntologyBiologicalProcessregulation of long-chain fatty acid import across plasma membrane

AKT1 AKT2

5.19e-057332GO:0010746
GeneOntologyBiologicalProcesspositive regulation of DNA-binding transcription factor activity

AKT1 PRKCI PRKCZ AR ESR2

5.55e-05261335GO:0051091
GeneOntologyBiologicalProcesscellular response to oxygen-containing compound

AACS AKT1 PRKCI AKT3 AKT2 PRKCZ AR PTK2 ESR2 TRPC6

5.92e-0514503310GO:1901701
GeneOntologyBiologicalProcesspositive regulation of monoatomic ion transport

AKT1 AKT3 AKT2 TRPC3 TRPC6

6.07e-05266335GO:0043270
GeneOntologyBiologicalProcesscellular response to insulin stimulus

AKT1 PRKCI AKT3 AKT2 PRKCZ

6.63e-05271335GO:0032869
GeneOntologyBiologicalProcesspositive regulation of transmembrane transport

AKT1 PRKCI AKT2 TRPC3 TRPC6

6.86e-05273335GO:0034764
GeneOntologyBiologicalProcesspositive regulation of D-glucose import

AKT1 PRKCI AKT2

6.95e-0550333GO:0046326
GeneOntologyBiologicalProcessperipheral nervous system myelin maintenance

AKT1 AKT2

8.87e-059332GO:0032287
GeneOntologyBiologicalProcessregulation of long-chain fatty acid import into cell

AKT1 AKT2

8.87e-059332GO:0140212
GeneOntologyBiologicalProcessregulation of TOR signaling

NPC1 AKT1 AKT3 ZMPSTE24

1.14e-04158334GO:0032006
GeneOntologyBiologicalProcesspeptidyl-serine phosphorylation

AKT1 PRKCI AKT3 AKT2 PRKCZ

1.19e-04307335GO:0018105
GeneOntologyBiologicalProcessresponse to nitrogen compound

AACS NPC1 AKT1 PRKCI AKT3 AKT2 PRKCZ PTK2 TRPC3

1.25e-041272339GO:1901698
GeneOntologyBiologicalProcessregulation of postsynaptic membrane neurotransmitter receptor levels

GRID1 GRID2 PRKCI PRKCZ

1.32e-04164334GO:0099072
GeneOntologyBiologicalProcessnegative regulation of fatty acid transport

AKT1 AKT2

1.35e-0411332GO:2000192
GeneOntologyBiologicalProcesspositive regulation of D-glucose transmembrane transport

AKT1 PRKCI AKT2

1.39e-0463333GO:0010828
GeneOntologyBiologicalProcesspeptidyl-serine modification

AKT1 PRKCI AKT3 AKT2 PRKCZ

1.43e-04319335GO:0018209
GeneOntologyBiologicalProcesscell surface receptor protein tyrosine kinase signaling pathway

AKT1 AKT2 PRKCZ AR PTK2 EPHA10 ESR2

1.49e-04747337GO:0007169
GeneOntologyBiologicalProcessprotein localization to plasma membrane

AKT1 PRKCI AKT2 PRKCZ AR

1.53e-04324335GO:0072659
GeneOntologyBiologicalProcessregulation of protein localization to cell periphery

AKT1 PRKCI PRKCZ AR

1.55e-04171334GO:1904375
GeneOntologyBiologicalProcesslong-chain fatty acid import across plasma membrane

AKT1 AKT2

1.62e-0412332GO:0015911
GeneOntologyBiologicalProcessresponse to peptide hormone

AKT1 PRKCI AKT3 AKT2 PRKCZ PTK2

1.72e-04530336GO:0043434
GeneOntologyBiologicalProcessregulation of postsynaptic membrane potential

GRID1 GRID2 AKT1 PRKCZ

1.88e-04180334GO:0060078
GeneOntologyBiologicalProcessTOR signaling

NPC1 AKT1 AKT3 ZMPSTE24

1.92e-04181334GO:0031929
GeneOntologyBiologicalProcessresponse to insulin

AKT1 PRKCI AKT3 AKT2 PRKCZ

1.97e-04342335GO:0032868
GeneOntologyBiologicalProcessepithelial cell differentiation involved in prostate gland development

AR ESR2

2.57e-0415332GO:0060742
GeneOntologyBiologicalProcessregulation of monoatomic ion transport

AKT1 AKT3 AKT2 TRPC3 TRPC6 KCNJ13

2.72e-04577336GO:0043269
GeneOntologyBiologicalProcessregulation of D-glucose import

AKT1 PRKCI AKT2

2.92e-0481333GO:0046324
GeneOntologyBiologicalProcessregulation of transmembrane transport

AKT1 PRKCI AKT2 TRPC3 TRPC6 KCNJ13

3.03e-04589336GO:0034762
GeneOntologyBiologicalProcessmammary gland epithelium development

AKT1 AKT2 AR

3.25e-0484333GO:0061180
GeneOntologyBiologicalProcessregulation of cytosolic calcium ion concentration

TRPC7 TRPC3 TRPC6

3.25e-0484333GO:0051480
GeneOntologyBiologicalProcessnegative regulation of apoptotic process

NPC1 AKT1 PRKCI AKT2 PRKCZ AR PTK2 ESR2

3.28e-041133338GO:0043066
GeneOntologyBiologicalProcesssingle fertilization

TRPC7 AR TRPC3 TRPC6

3.33e-04209334GO:0007338
GeneOntologyBiologicalProcesspositive regulation of glycogen biosynthetic process

AKT1 AKT2

3.74e-0418332GO:0045725
GeneOntologyBiologicalProcessmyelin maintenance

AKT1 AKT2

3.74e-0418332GO:0043217
GeneOntologyBiologicalProcessnegative regulation of programmed cell death

NPC1 AKT1 PRKCI AKT2 PRKCZ AR PTK2 ESR2

4.09e-041171338GO:0043069
GeneOntologyBiologicalProcessmammary gland epithelial cell differentiation

AKT1 AKT2

4.17e-0419332GO:0060644
GeneOntologyBiologicalProcessbehavior

NPC1 GRID1 AKT1 PRKCZ ZMPSTE24 AR ESR2

4.37e-04891337GO:0007610
GeneOntologyBiologicalProcesslong-chain fatty acid import into cell

AKT1 AKT2

4.63e-0420332GO:0044539
GeneOntologyBiologicalProcessmembrane organization

NPC1 AKT1 PRKCI AKT2 TMEM43 ZMPSTE24 AR

5.10e-04914337GO:0061024
GeneOntologyBiologicalProcessprotein localization to cell periphery

AKT1 PRKCI AKT2 PRKCZ AR

5.18e-04422335GO:1990778
GeneOntologyBiologicalProcessinorganic cation transmembrane transport

SLC47A1 AKT1 SLC9C1 TRPC7 TRPC3 TRPC6 KCNJ13

5.37e-04922337GO:0098662
GeneOntologyBiologicalProcessglucan metabolic process

NPC1 AKT1 AKT2

5.59e-04101333GO:0044042
GeneOntologyBiologicalProcessregulation of sodium ion transport

AKT1 AKT3 AKT2

5.59e-04101333GO:0002028
GeneOntologyBiologicalProcessfatty acid transmembrane transport

AKT1 AKT2

5.62e-0422332GO:1902001
GeneOntologyBiologicalProcessD-glucose import

AKT1 PRKCI AKT2

5.75e-04102333GO:0046323
GeneOntologyBiologicalProcessmonoatomic cation transmembrane transport

SLC47A1 AKT1 SLC9C1 TRPC7 TRPC3 TRPC6 KCNJ13

6.10e-04942337GO:0098655
GeneOntologyBiologicalProcessregulation of D-glucose transmembrane transport

AKT1 PRKCI AKT2

6.26e-04105333GO:0010827
GeneOntologyBiologicalProcesschemical homeostasis

AACS NPC1 AKT1 SLC9C1 TRPC7 PTK2 TRPC3 TRPC6

6.29e-041249338GO:0048878
GeneOntologyBiologicalProcesspositive regulation of glycogen metabolic process

AKT1 AKT2

6.70e-0424332GO:0070875
GeneOntologyBiologicalProcessregulation of fatty acid beta-oxidation

AKT1 AKT2

6.70e-0424332GO:0031998
GeneOntologyBiologicalProcessregulation of DNA-binding transcription factor activity

AKT1 PRKCI PRKCZ AR ESR2

6.86e-04449335GO:0051090
GeneOntologyBiologicalProcessorgan growth

AKT1 ZMPSTE24 AR PTK2

7.15e-04256334GO:0035265
GeneOntologyBiologicalProcesslipid import into cell

AKT1 AKT2

7.28e-0425332GO:0140354
GeneOntologyBiologicalProcesspeptidyl-amino acid modification

AKT1 PRKCI AKT3 AKT2 PRKCZ PTK2 TRPC6

7.53e-04976337GO:0018193
GeneOntologyBiologicalProcessnegative regulation of autophagy

NPC1 AKT1 PTK2

7.55e-04112333GO:0010507
GeneOntologyBiologicalProcessprotein localization to membrane

NPC1 AKT1 PRKCI AKT2 PRKCZ AR

7.85e-04705336GO:0072657
GeneOntologyBiologicalProcessfertilization

TRPC7 AR TRPC3 TRPC6

7.90e-04263334GO:0009566
GeneOntologyBiologicalProcesspeptidyl-threonine phosphorylation

AKT1 AKT3 TRPC6

8.15e-04115333GO:0018107
GeneOntologyBiologicalProcesspositive regulation of fibroblast migration

AKT1 PTK2

8.50e-0427332GO:0010763
GeneOntologyBiologicalProcesssodium ion transport

AKT1 AKT3 AKT2 SLC9C1

9.33e-04275334GO:0006814
GeneOntologyBiologicalProcessinorganic ion transmembrane transport

SLC47A1 AKT1 SLC9C1 TRPC7 TRPC3 TRPC6 KCNJ13

9.60e-041017337GO:0098660
GeneOntologyBiologicalProcesspeptidyl-threonine modification

AKT1 AKT3 TRPC6

1.04e-03125333GO:0018210
GeneOntologyBiologicalProcessregulation of metal ion transport

AKT1 AKT3 AKT2 TRPC3 TRPC6

1.04e-03493335GO:0010959
GeneOntologyBiologicalProcesspolysaccharide metabolic process

NPC1 AKT1 AKT2

1.06e-03126333GO:0005976
GeneOntologyBiologicalProcesscellular response to nitrogen compound

AKT1 PRKCI AKT3 AKT2 PRKCZ PTK2

1.10e-03752336GO:1901699
GeneOntologyBiologicalProcessregulation of protein localization to plasma membrane

AKT1 PRKCI AR

1.11e-03128333GO:1903076
GeneOntologyBiologicalProcessresponse to organic cyclic compound

AACS NPC1 AKT1 AKT2 AR ESR2 TRPC3

1.14e-031048337GO:0014070
GeneOntologyBiologicalProcesspositive regulation of protein localization to membrane

AKT1 PRKCI AKT2

1.16e-03130333GO:1905477
GeneOntologyBiologicalProcessexcitatory postsynaptic potential

GRID2 AKT1 PRKCZ

1.16e-03130333GO:0060079
GeneOntologyBiologicalProcessnegative regulation of organic acid transport

AKT1 AKT2

1.19e-0332332GO:0032891
GeneOntologyBiologicalProcesscalcium ion transport

AKT1 TRPC7 ZMPSTE24 TRPC3 TRPC6

1.20e-03509335GO:0006816
GeneOntologyBiologicalProcessregulation of glucose metabolic process

AKT1 AKT2 ZMPSTE24

1.27e-03134333GO:0010906
GeneOntologyBiologicalProcessperipheral nervous system axon ensheathment

AKT1 AKT2

1.27e-0333332GO:0032292
GeneOntologyBiologicalProcessmyelination in peripheral nervous system

AKT1 AKT2

1.27e-0333332GO:0022011
GeneOntologyBiologicalProcessprostate gland epithelium morphogenesis

AR ESR2

1.27e-0333332GO:0060740
GeneOntologyBiologicalProcessimport into cell

NPC1 SLC47A1 AKT1 AKT2 SLC9C1 PTK2 KCNJ13

1.32e-031074337GO:0098657
GeneOntologyBiologicalProcessprostate gland morphogenesis

AR ESR2

1.35e-0334332GO:0060512
GeneOntologyBiologicalProcesspositive regulation of glial cell proliferation

PRKCI PTK2

1.35e-0334332GO:0060252
GeneOntologyBiologicalProcessepidermal growth factor receptor signaling pathway

AKT1 PTK2 ESR2

1.41e-03139333GO:0007173
GeneOntologyBiologicalProcessnegative regulation of macroautophagy

NPC1 AKT1

1.43e-0335332GO:0016242
GeneOntologyBiologicalProcesslocalization within membrane

NPC1 AKT1 PRKCI AKT2 PRKCZ AR

1.49e-03798336GO:0051668
GeneOntologyBiologicalProcesspositive regulation of molecular function

AKT1 PRKCI AKT2 PRKCZ AR PTK2 ESR2 TRPC6

1.52e-031430338GO:0044093
GeneOntologyBiologicalProcesscellular response to estrogen stimulus

AR ESR2

1.60e-0337332GO:0071391
GeneOntologyBiologicalProcessanoikis

AKT1 PTK2

1.60e-0337332GO:0043276
GeneOntologyCellularComponentPAR polarity complex

PRKCI PRKCZ

3.61e-056332GO:0120157
GeneOntologyCellularComponentglutamatergic synapse

GRID1 GRID2 AKT1 PRKCI RPSA PRKCZ PTK2

2.38e-04817337GO:0098978
GeneOntologyCellularComponentmonoatomic ion channel complex

GRID2 TRPC7 TRPC3 TRPC6 KCNJ13

2.95e-04378335GO:0034702
GeneOntologyCellularComponentcell leading edge

AKT1 PRKCI AKT2 PRKCZ PTK2

1.05e-03500335GO:0031252
GeneOntologyCellularComponenttransmembrane transporter complex

GRID2 TRPC7 TRPC3 TRPC6 KCNJ13

1.28e-03523335GO:1902495
GeneOntologyCellularComponenttransporter complex

GRID2 TRPC7 TRPC3 TRPC6 KCNJ13

1.60e-03550335GO:1990351
GeneOntologyCellularComponentnuclear envelope

NPC1 TMEM43 PRKCZ TRPC7 ZMPSTE24

1.73e-03560335GO:0005635
GeneOntologyCellularComponentcell-cell junction

AKT1 PRKCI PRKCZ PTK2 TRPC6

2.19e-03591335GO:0005911
GeneOntologyCellularComponentsomatodendritic compartment

GRID2 RPSA PRKCZ AR PTK2 EPHA10 ESR2

2.63e-031228337GO:0036477
GeneOntologyCellularComponentcell cortex

AKT1 AKT2 PRKCZ PTK2

2.66e-03371334GO:0005938
GeneOntologyCellularComponentciliary basal body

AKT1 PTK2 RTTN

3.55e-03195333GO:0036064
GeneOntologyCellularComponentnuclear inner membrane

TMEM43 ZMPSTE24

3.91e-0359332GO:0005637
MousePhenoincreased circulating pituitary hormone level

NPC1 GRID2 ZMPSTE24 AR ESR2

3.35e-06110305MP:0005117
MousePhenoincreased pituitary hormone level

NPC1 GRID2 ZMPSTE24 AR ESR2

7.06e-06128305MP:0003973
MousePhenomammary gland alveolar hyperplasia

AKT1 ESR2

1.33e-053302MP:0001884
MousePhenoabnormal circulating pituitary hormone level

NPC1 GRID2 ZMPSTE24 AR ESR2

2.96e-05172305MP:0005116
MousePhenoincreased hormone level

NPC1 GRID2 AKT1 AKT2 ZMPSTE24 AR ESR2 TMEM117

4.46e-05641308MP:0014454
MousePhenoincreased circulating luteinizing hormone level

NPC1 AR ESR2

5.57e-0535303MP:0001751
MousePhenoincreased luteinizing hormone level

NPC1 AR ESR2

7.15e-0538303MP:0005133
MousePhenoabnormal pituitary hormone level

NPC1 GRID2 ZMPSTE24 AR ESR2

8.37e-05214305MP:0003965
MousePhenosmall amniotic cavity

PRKCI PTK2

9.29e-057302MP:0012104
MousePhenodecreased neuron number

NPC1 GRID2 TMEM43 ESR2 TRPC3 TMEM117

1.25e-04376306MP:0008948
MousePhenoincreased circulating hormone level

NPC1 GRID2 AKT2 ZMPSTE24 AR ESR2 TMEM117

1.77e-04578307MP:0014456
MousePhenoabnormal Purkinje cell dendrite morphology

NPC1 GRID2 TRPC3

2.54e-0458303MP:0008572
MousePhenoincreased circulating gonadotropin level

NPC1 AR ESR2

3.40e-0464303MP:0003362
MousePhenoabnormal head fold morphology

PRKCI SPTSSA PTK2

3.40e-0464303MP:0011257
MousePhenoabnormal luteinizing hormone level

NPC1 AR ESR2

3.40e-0464303MP:0003969
MousePhenoabnormal neuron number

NPC1 GRID2 TMEM43 ESR2 TRPC3 TMEM117

3.55e-04456306MP:0008946
MousePhenodecreased Purkinje cell number

NPC1 GRID2 TRPC3

3.89e-0467303MP:0000880
MousePhenoabnormal Purkinje cell number

NPC1 GRID2 TRPC3

4.25e-0469303MP:0000878
DomainPkinase_C

AKT1 PRKCI AKT3 AKT2 PRKCZ

6.15e-0937345IPR017892
DomainPkinase_C

AKT1 PRKCI AKT3 AKT2 PRKCZ

1.19e-0842345PF00433
DomainAGC-kinase_C

AKT1 PRKCI AKT3 AKT2 PRKCZ

5.26e-0856345IPR000961
DomainAGC_KINASE_CTER

AKT1 PRKCI AKT3 AKT2 PRKCZ

5.26e-0856345PS51285
DomainS_TK_X

AKT1 PRKCI AKT3 AKT2 PRKCZ

5.26e-0856345SM00133
DomainTRP_dom

TRPC7 TRPC3 TRPC6

1.10e-076343IPR013555
DomainTRP_2

TRPC7 TRPC3 TRPC6

1.10e-076343PF08344
DomainTRPC_channel

TRPC7 TRPC3 TRPC6

1.92e-077343IPR002153
DomainTRP_channel

TRPC7 TRPC3 TRPC6

9.00e-0711343IPR004729
DomainPKC

PRKCI PRKCZ

3.22e-062342IPR012233
DomainPROTEIN_KINASE_ATP

AKT1 PRKCI AKT3 AKT2 PRKCZ PTK2 EPHA10

1.57e-05459347PS00107
DomainProt_kinase_dom

AKT1 PRKCI AKT3 AKT2 PRKCZ PTK2 EPHA10

2.35e-05489347IPR000719
DomainPROTEIN_KINASE_DOM

AKT1 PRKCI AKT3 AKT2 PRKCZ PTK2 EPHA10

2.48e-05493347PS50011
DomainKinase-like_dom

AKT1 PRKCI AKT3 AKT2 PRKCZ PTK2 EPHA10

4.54e-05542347IPR011009
DomainIon_trans_dom

SLC9C1 TRPC7 TRPC3 TRPC6

5.30e-05114344IPR005821
DomainIon_trans

SLC9C1 TRPC7 TRPC3 TRPC6

5.30e-05114344PF00520
DomainProtein_kinase_ATP_BS

AKT1 PRKCI AKT3 AKT2 PRKCZ PTK2

5.58e-05379346IPR017441
DomainPB1

PRKCI PRKCZ

2.89e-0414342SM00666
DomainPB1

PRKCI PRKCZ

2.89e-0414342PS51745
DomainPB1

PRKCI PRKCZ

2.89e-0414342PF00564
DomainPB1_dom

PRKCI PRKCZ

2.89e-0414342IPR000270
DomainSer/Thr_kinase_AS

AKT1 PRKCI AKT3 AKT2 PRKCZ

4.38e-04357345IPR008271
DomainS_TKc

AKT1 PRKCI AKT3 AKT2 PRKCZ

4.49e-04359345SM00220
DomainPROTEIN_KINASE_ST

AKT1 PRKCI AKT3 AKT2 PRKCZ

4.66e-04362345PS00108
DomainIontro_rcpt

GRID1 GRID2

4.83e-0418342IPR001320
DomainLig_chan

GRID1 GRID2

4.83e-0418342PF00060
DomainLig_chan-Glu_bd

GRID1 GRID2

4.83e-0418342PF10613
DomainPBPe

GRID1 GRID2

4.83e-0418342SM00079
DomainIono_rcpt_met

GRID1 GRID2

4.83e-0418342IPR001508
DomainGlu/Gly-bd

GRID1 GRID2

4.83e-0418342IPR019594
DomainLig_chan-Glu_bd

GRID1 GRID2

4.83e-0418342SM00918
DomainPkinase

AKT1 PRKCI AKT3 AKT2 PRKCZ

5.88e-04381345PF00069
DomainDAG/PE-bd

PRKCI PRKCZ

6.61e-0421342IPR020454
DomainANF_receptor

GRID1 GRID2

2.06e-0337342PF01094
DomainANF_lig-bd_rcpt

GRID1 GRID2

2.06e-0337342IPR001828
DomainPeripla_BP_I

GRID1 GRID2

2.29e-0339342IPR028082
Domainzf-C4

AR ESR2

3.17e-0346342PF00105
DomainNUCLEAR_REC_DBD_1

AR ESR2

3.17e-0346342PS00031
DomainZnf_hrmn_rcpt

AR ESR2

3.17e-0346342IPR001628
DomainZnF_C4

AR ESR2

3.17e-0346342SM00399
DomainNUCLEAR_REC_DBD_2

AR ESR2

3.17e-0346342PS51030
Domain-

AR ESR2

3.30e-03473421.10.565.10
DomainHOLI

AR ESR2

3.44e-0348342SM00430
DomainNucl_hrmn_rcpt_lig-bd

AR ESR2

3.44e-0348342IPR000536
DomainHormone_recep

AR ESR2

3.44e-0348342PF00104
DomainC1_1

PRKCI PRKCZ

4.82e-0357342PF00130
Domain-

AR ESR2

4.82e-03573423.30.50.10
PathwayREACTOME_EXTRA_NUCLEAR_ESTROGEN_SIGNALING

AKT1 AKT3 AKT2 PRKCZ PTK2 ESR2

4.54e-0971286MM15590
PathwayKEGG_MEDICUS_ENV_FACTOR_NNK_NNN_TO_PI3K_SIGNALING_PATHWAY_N01350

AKT1 AKT3 AKT2 ESR2

6.10e-0912284M47798
PathwayREACTOME_EXTRA_NUCLEAR_ESTROGEN_SIGNALING

AKT1 AKT3 AKT2 PRKCZ PTK2 ESR2

6.35e-0975286M27874
PathwayKEGG_MEDICUS_VARIANT_LOSS_OF_NKX3_1_TO_PI3K_SIGNALING_PATHWAY

AKT1 AKT3 AKT2

7.00e-085283M48999
PathwayREACTOME_ESTROGEN_DEPENDENT_NUCLEAR_EVENTS_DOWNSTREAM_OF_ESR_MEMBRANE_SIGNALING

AKT1 AKT3 AKT2 PTK2

1.29e-0724284M27952
PathwayKEGG_MEDICUS_REFERENCE_MAGI_PTEN_SIGNALING_PATHWAY

AKT1 AKT3 AKT2

1.40e-076283M47523
PathwayPID_INSULIN_GLUCOSE_PATHWAY

AKT1 PRKCI AKT2 PRKCZ

1.81e-0726284M247
PathwayREACTOME_ESR_MEDIATED_SIGNALING

AKT1 AKT3 AKT2 PRKCZ PTK2 ESR2

2.00e-07133286MM15529
PathwayKEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_PI3K_TO_PI3K_SIGNALING_PATHWAY

AKT1 AKT3 AKT2

2.44e-077283M47407
PathwayKEGG_MEDICUS_REFERENCE_ACH_CHRN_PI3K_SIGNALING_PATHWAY

AKT1 AKT3 AKT2

2.44e-077283M47790
PathwayPID_NEPHRIN_NEPH1_PATHWAY

AKT1 PRKCI PRKCZ TRPC6

3.78e-0731284M193
PathwayKEGG_MEDICUS_VARIANT_AMPLIFIED_PDGFR_TO_PI3K_SIGNALING_PATHWAY

AKT1 AKT3 AKT2

3.90e-078283M47399
PathwayKEGG_MEDICUS_VARIANT_AMPLIFIED_EGFR_TO_PI3K_SIGNALING_PATHWAY

AKT1 AKT3 AKT2

3.90e-078283M47394
PathwayKEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_EGFR_TO_PI3K_SIGNALING_PATHWAY

AKT1 AKT3 AKT2

3.90e-078283M47395
PathwayKEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_KIT_TO_PI3K_SIGNALING_PATHWAY

AKT1 AKT3 AKT2

3.90e-078283M47404
PathwayKEGG_MEDICUS_VARIANT_EML4_ALK_FUSION_KINASE_TO_PI3K_SIGNALING_PATHWAY

AKT1 AKT3 AKT2

3.90e-078283M47405
PathwayKEGG_MEDICUS_REFERENCE_P4_PR_PI3K_SIGNALING_PATHWAY

AKT1 AKT3 AKT2

3.90e-078283M47803
PathwayREACTOME_RUNX2_REGULATES_GENES_INVOLVED_IN_CELL_MIGRATION

AKT1 AKT3 AKT2

3.90e-078283M27806
PathwayKEGG_MEDICUS_VARIANT_TGFA_OVEREXPRESSION_TO_PI3K_SIGNALING_PATHWAY

AKT1 AKT3 AKT2

3.90e-078283M47482
PathwayKEGG_MEDICUS_VARIANT_EGF_OVEREXPRESSION_TO_PI3K_SIGNALING_PATHWAY

AKT1 AKT3 AKT2

3.90e-078283M47498
PathwayKEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_RET_TO_PI3K_SIGNALING_PATHWAY

AKT1 AKT3 AKT2

3.90e-078283M47715
PathwayPID_MET_PATHWAY

AKT1 PRKCI AKT2 PRKCZ PTK2

4.32e-0779285M48
PathwayWP_GLIOBLASTOMA_SIGNALING

AKT1 PRKCI AKT3 AKT2 PRKCZ

5.53e-0783285M39637
PathwayREACTOME_PLATELET_ACTIVATION_SIGNALING_AND_AGGREGATION

LY6G6F AKT1 PRKCZ TRPC7 PTK2 TRPC3 TRPC6

5.84e-07261287M1077
PathwayKEGG_MEDICUS_VARIANT_AMPLIFIED_FGFR_TO_PI3K_SIGNALING_PATHWAY

AKT1 AKT3 AKT2

5.85e-079283M47397
PathwayKEGG_MEDICUS_REFERENCE_EGF_EGFR_PI3K_SIGNALING_PATHWAY

AKT1 AKT3 AKT2

5.85e-079283M47392
PathwayKEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_KRAS_NRAS_TO_PI3K_SIGNALING_PATHWAY

AKT1 AKT3 AKT2

5.85e-079283M47391
PathwayKEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_MET_TO_PI3K_SIGNALING_PATHWAY

AKT1 AKT3 AKT2

5.85e-079283M47402
PathwayKEGG_MEDICUS_REFERENCE_MEMBRANE_INITIATED_PROGESTERONE_SIGNALING_PATHWAY

AKT1 AKT3 AKT2

5.85e-079283M47802
PathwayKEGG_MEDICUS_VARIANT_AMPLIFIED_MET_TO_PI3K_SIGNALING_PATHWAY

AKT1 AKT3 AKT2

5.85e-079283M47490
PathwayKEGG_MEDICUS_REFERENCE_TGFA_EGFR_PI3K_SIGNALING_PATHWAY

AKT1 AKT3 AKT2

5.85e-079283M47481
PathwayREACTOME_ESTROGEN_DEPENDENT_NUCLEAR_EVENTS_DOWNSTREAM_OF_ESR_MEMBRANE_SIGNALING

AKT1 AKT3 AKT2

5.85e-079283MM15666
PathwayKEGG_MEDICUS_REFERENCE_ICOSLG_ICOS_PI3K_SIGNALING_PATHWAY

AKT1 AKT3 AKT2

5.85e-079283M47972
PathwayREACTOME_ROLE_OF_SECOND_MESSENGERS_IN_NETRIN_1_SIGNALING

TRPC7 TRPC3 TRPC6

8.34e-0710283M27330
PathwayKEGG_MEDICUS_VARIANT_EGFR_OVEREXPRESSION_TO_PI3K_SIGNALING_PATHWAY

AKT1 AKT3 AKT2

8.34e-0710283M47400
PathwayKEGG_MEDICUS_REFERENCE_HGF_MET_PI3K_SIGNALING_PATHWAY

AKT1 AKT3 AKT2

8.34e-0710283M47401
PathwayKEGG_MEDICUS_REFERENCE_CD80_CD86_CD28_PI3K_SIGNALING_PATHWAY

AKT1 AKT3 AKT2

8.34e-0710283M47615
PathwayREACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_NUCLEUS

AKT1 AKT3 AKT2

8.34e-0710283M27095
PathwayREACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_NUCLEUS

AKT1 AKT3 AKT2

8.34e-0710283MM14778
PathwayKEGG_MEDICUS_ENV_FACTOR_NICOTINE_NNK_TO_PI3K_SIGNALING_PATHWAY

AKT1 AKT3 AKT2

1.15e-0611283M47797
PathwayKEGG_MEDICUS_REFERENCE_KITLG_KIT_PI3K_SIGNALING_PATHWAY

AKT1 AKT3 AKT2

1.15e-0611283M47403
PathwayKEGG_MEDICUS_VARIANT_BCR_ABL_FUSION_KINASE_TO_PI3K_SIGNALING_PATHWAY

AKT1 AKT3 AKT2

1.15e-0611283M47406
PathwayKEGG_MEDICUS_REFERENCE_IGF2_IGF1R_PI3K_SIGNALING_PATHWAY

AKT1 AKT3 AKT2

1.15e-0611283M47484
PathwayKEGG_MEDICUS_REFERENCE_EREG_EGFR_PI3K_SIGNALING_PATHWAY

AKT1 AKT3 AKT2

1.15e-0611283M47499
PathwayKEGG_MEDICUS_REFERENCE_NRG_ERBB4_PI3K_SIGNALING_PATHWAY

AKT1 AKT3 AKT2

1.15e-0611283M47756
PathwayKEGG_MEDICUS_ENV_FACTOR_NNK_NNN_TO_PI3K_SIGNALING_PATHWAY_N01339

AKT1 AKT3 AKT2

1.15e-0611283M47791
PathwayKEGG_MEDICUS_REFERENCE_AREG_EGFR_PI3K_SIGNALING_PATHWAY

AKT1 AKT3 AKT2

1.15e-0611283M47501
PathwayKEGG_MEDICUS_VARIANT_ERBB2_OVEREXPRESSION_TO_PI3K_SIGNALING_PATHWAY

AKT1 AKT3 AKT2

1.53e-0612283M47393
PathwayKEGG_MEDICUS_REFERENCE_CXCR4_GNAI_PI3K_BAD_SIGNALING_PATHWAY

AKT1 AKT3 AKT2

1.53e-0612283M47558
PathwayKEGG_MEDICUS_PATHOGEN_HIV_GP120_TO_CXCR4_GNAI_PI3K_BAD_SIGNALING_PATHWAY

AKT1 AKT3 AKT2

1.53e-0612283M47559
PathwayREACTOME_SARS_COV_2_TARGETS_HOST_INTRACELLULAR_SIGNALLING_AND_REGULATORY_PATHWAYS

AKT1 AKT3 AKT2

1.53e-0612283M45022
PathwayREACTOME_REGULATION_OF_LOCALIZATION_OF_FOXO_TRANSCRIPTION_FACTORS

AKT1 AKT3 AKT2

1.53e-0612283MM15657
PathwayREACTOME_REGULATION_OF_LOCALIZATION_OF_FOXO_TRANSCRIPTION_FACTORS

AKT1 AKT3 AKT2

1.53e-0612283M27939
PathwayREACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_CYTOSOL

AKT1 AKT3 AKT2

1.53e-0612283MM14777
PathwayREACTOME_DOWNREGULATION_OF_ERBB2_ERBB3_SIGNALING

AKT1 AKT3 AKT2

1.53e-0612283MM14550
PathwayREACTOME_NETRIN_1_SIGNALING

TRPC7 PTK2 TRPC3 TRPC6

1.60e-0644284M875
PathwayPID_INSULIN_PATHWAY

AKT1 PRKCI AKT2 PRKCZ

1.60e-0644284M16
PathwayREACTOME_SIGNALING_BY_VEGF

AKT1 AKT3 AKT2 PRKCZ PTK2

1.62e-06103285MM14752
PathwayREACTOME_SIGNALING_BY_NUCLEAR_RECEPTORS

AKT1 AKT3 AKT2 PRKCZ PTK2 ESR2

1.68e-06191286MM15586
PathwayREACTOME_SIGNALING_BY_VEGF

AKT1 AKT3 AKT2 PRKCZ PTK2

1.87e-06106285M27077
PathwayKEGG_MEDICUS_REFERENCE_PDGF_PDGFR_PI3K_SIGNALING_PATHWAY

AKT1 AKT3 AKT2

1.98e-0613283M47398
PathwayKEGG_MEDICUS_REFERENCE_IGF_IGF1R_PI3K_SIGNALING_PATHWAY

AKT1 AKT3 AKT2

1.98e-0613283M47603
PathwayREACTOME_DOWNREGULATION_OF_ERBB2_ERBB3_SIGNALING

AKT1 AKT3 AKT2

1.98e-0613283M549
PathwayREACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS

TRPC7 TRPC3 TRPC6

1.98e-0613283MM14553
PathwayKEGG_MEDICUS_VARIANT_DUPLICATION_OR_MUTATION_ACTIVATED_FLT3_TO_RAS_PI3K_SIGNALING_PATHWAY

AKT1 AKT3 AKT2

2.52e-0614283M47390
PathwayREACTOME_REGULATION_OF_TP53_ACTIVITY_THROUGH_ASSOCIATION_WITH_CO_FACTORS

AKT1 AKT3 AKT2

2.52e-0614283MM15341
PathwayREACTOME_REGULATION_OF_TP53_ACTIVITY_THROUGH_ASSOCIATION_WITH_CO_FACTORS

AKT1 AKT3 AKT2

2.52e-0614283M27638
PathwayKEGG_MEDICUS_REFERENCE_IGF_IGFR_PI3K_NFKB_SIGNALING_PATHWAY

AKT1 AKT3 AKT2

2.52e-0614283M47467
PathwayKEGG_MEDICUS_REFERENCE_EGF_EGFR_PI3K_NFKB_SIGNALING_PATHWAY

AKT1 AKT3 AKT2

2.52e-0614283M47536
PathwayREACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_CYTOSOL

AKT1 AKT3 AKT2

2.52e-0614283M3862
PathwayKEGG_MEDICUS_REFERENCE_EGF_EGFR_RAS_PI3K_SIGNALING_PATHWAY

AKT1 AKT3 AKT2

3.14e-0615283M47389
PathwayKEGG_MEDICUS_REFERENCE_RELN_VLDLR_PI3K_SIGNALING_PATHWAY

AKT1 AKT3 AKT2

3.14e-0615283M47663
PathwayREACTOME_ACTIVATION_OF_BAD_AND_TRANSLOCATION_TO_MITOCHONDRIA

AKT1 AKT3 AKT2

3.14e-0615283M26902
PathwayKEGG_MEDICUS_REFERENCE_FLT3LG_FLT3_RAS_PI3K_SIGNALING_PATHWAY

AKT1 AKT3 AKT2

3.14e-0615283M47475
PathwayWP_RIOK1_AND_RIOK2_IN_EGFR_AND_PI3KMEDIATED_TUMORIGENESIS

AKT1 AKT3 AKT2

3.14e-0615283M48306
PathwayKEGG_MEDICUS_REFERENCE_BCR_BCAP_CD19_PI3K_SIGNALING_PATHWAY

AKT1 AKT3 AKT2

3.14e-0615283M47971
PathwayWP_NRP1TRIGGERED_SIGNALING_IN_PANCREATIC_CANCER

AKT1 AKT3 AKT2 PTK2

3.68e-0654284M42568
PathwayREACTOME_ESR_MEDIATED_SIGNALING

AKT1 AKT3 AKT2 PRKCZ PTK2 ESR2

3.82e-06220286M27794
PathwayREACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS

TRPC7 TRPC3 TRPC6

3.86e-0616283M26945
PathwayWP_INVOLVEMENT_OF_SECRETASE_IN_NEURODEGENERATIVE_DISEASES

AKT1 AKT3 AKT2

4.68e-0617283M48086
PathwaySA_PTEN_PATHWAY

AKT1 AKT3 AKT2

4.68e-0617283M12771
PathwaySA_TRKA_RECEPTOR

AKT1 AKT3 AKT2

4.68e-0617283M18895
PathwayWP_MET_IN_TYPE_1_PAPILLARY_RENAL_CELL_CARCINOMA

AKT1 AKT3 AKT2 PTK2

5.26e-0659284M39750
PathwayKEGG_TIGHT_JUNCTION

AKT1 PRKCI AKT3 AKT2 PRKCZ

5.52e-06132285M11355
PathwayKEGG_INSULIN_SIGNALING_PATHWAY

AKT1 PRKCI AKT3 AKT2 PRKCZ

6.62e-06137285M18155
PathwayWP_TGFBETA_SIGNALING_IN_THYROID_CELLS_FOR_EPITHELIALMESENCHYMAL_TRANSITION

AKT1 AKT3 AKT2

6.66e-0619283M39370
PathwayKEGG_MEDICUS_REFERENCE_PP2A_AKT_SIGNALING_PATHWAY

AKT1 AKT3 AKT2

6.66e-0619283M47525
PathwayWP_ALPHA_6_BETA_4_INTEGRIN_SIGNALING_PATHWAY

AKT1 RPSA AR PTK2

8.24e-0666284MM15925
PathwaySIG_PIP3_SIGNALING_IN_CARDIAC_MYOCTES

AKT1 AKT3 AKT2 PTK2

8.76e-0667284M295
PathwayREACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS

AKT1 AKT3 AKT2

9.11e-0621283M14966
PathwayREACTOME_CTLA4_INHIBITORY_SIGNALING

AKT1 AKT3 AKT2

9.11e-0621283M5876
PathwayREACTOME_CTLA4_INHIBITORY_SIGNALING

AKT1 AKT3 AKT2

9.11e-0621283MM14996
PathwayREACTOME_PLATELET_ACTIVATION_SIGNALING_AND_AGGREGATION

LY6G6F AKT1 TRPC7 PTK2 TRPC3 TRPC6

9.32e-06257286MM15454
PathwayREACTOME_CD28_DEPENDENT_PI3K_AKT_SIGNALING

AKT1 AKT3 AKT2

1.05e-0522283M13897
PathwayREACTOME_FOXO_MEDIATED_TRANSCRIPTION

AKT1 AKT3 AKT2

1.05e-0522283MM15656
PathwayKEGG_MEDICUS_REFERENCE_CD80_CD86_CTLA4_PP2A_SIGNALING_PATHWAY

AKT1 AKT3 AKT2

1.05e-0522283M47919
PathwayWP_SIGNAL_TRANSDUCTION_OF_S1P_RECEPTOR

AKT1 AKT3 AKT2

1.21e-0523283MM15952
PathwayWP_SILDENAFIL_TREATMENT

AKT1 AKT3 AKT2

1.21e-0523283M46455
PathwayREACTOME_CD28_DEPENDENT_PI3K_AKT_SIGNALING

AKT1 AKT3 AKT2

1.21e-0523283MM14993
PathwayKEGG_MEDICUS_PATHOGEN_KSHV_VGPCR_TO_GNB_G_PI3K_AKT_SIGNALING_PATHWAY

AKT1 AKT3 AKT2

1.38e-0524283M47460
Pubmed

Activation of protein kinase B beta and gamma isoforms by insulin in vivo and by 3-phosphoinositide-dependent protein kinase-1 in vitro: comparison with protein kinase B alpha.

AKT1 AKT3 AKT2 PRKCZ

4.29e-1253549512493
Pubmed

A WD-FYVE protein binds to the kinases Akt and PKCzeta/lambda.

AKT1 PRKCI AKT2 PRKCZ

4.29e-12535416792529
Pubmed

Signalling crosstalk in FGF2-mediated protection of endothelial cells from HIV-gp120.

AKT1 PRKCI AKT3 AKT2 PRKCZ

4.01e-112535515689238
Pubmed

Deletion of PKBalpha/Akt1 affects thymic development.

AKT1 AKT3 AKT2

9.34e-10335317912369
Pubmed

Differential activation of AKT isoforms by growth factors in human myotubes.

AKT1 AKT3 AKT2

9.34e-10335337879895
Pubmed

Differential prognostic values of the three AKT isoforms in acute myeloid leukemia.

AKT1 AKT3 AKT2

9.34e-10335338528080
Pubmed

Increased level of phosphorylated akt measured by chemiluminescence-linked immunosorbent assay is a predictor of poor prognosis in primary breast cancer overexpressing ErbB-2.

AKT1 AKT3 AKT2

9.34e-10335315987444
Pubmed

MicroRNAs differentially regulated by Akt isoforms control EMT and stem cell renewal in cancer cells.

AKT1 AKT3 AKT2

9.34e-10335319825827
Pubmed

Kinetic mechanism of AKT/PKB enzyme family.

AKT1 AKT3 AKT2

9.34e-10335316540465
Pubmed

Molecular alterations in AKT1, AKT2 and AKT3 detected in breast and prostatic cancer by FISH.

AKT1 AKT3 AKT2

9.34e-10335320102399
Pubmed

Distinct roles of the three Akt isoforms in lactogenic differentiation and involution.

AKT1 AKT3 AKT2

9.34e-10335318561256
Pubmed

Major contribution of the 3/6/7 class of TRPC channels to myocardial ischemia/reperfusion and cellular hypoxia/reoxygenation injuries.

TRPC7 TRPC3 TRPC6

9.34e-10335328526717
Pubmed

Differential effects of Akt isoforms on somatic cell reprogramming.

AKT1 AKT3 AKT2

9.34e-10335325037569
Pubmed

All Three AKT Isoforms Can Upregulate Oxygen Metabolism and Lactate Production in Human Hepatocellular Carcinoma Cell Lines.

AKT1 AKT3 AKT2

9.34e-10335338396845
Pubmed

AKT isoforms have distinct hippocampal expression and roles in synaptic plasticity.

AKT1 AKT3 AKT2

9.34e-10335329173281
Pubmed

Akt/PKB isoforms expression in the human lumbar herniated disc: correlation with clinical and MRI findings.

AKT1 AKT3 AKT2

9.34e-10335321590431
Pubmed

Protein kinase Akt activity in human thyroid tumors.

AKT1 AKT3 AKT2

9.34e-10335329235817
Pubmed

Immunohistological Examination of AKT Isoforms in the Brain: Cell-Type Specificity That May Underlie AKT's Role in Complex Brain Disorders and Neurological Disease.

AKT1 AKT3 AKT2

9.34e-10335334296180
Pubmed

Sex differences in the mechanism of Met5-enkephalin-induced cardioprotection: role of PI3K/Akt.

AKT1 AKT3 AKT2

9.34e-10335317982014
Pubmed

Opposing functions of Akt isoforms in lung tumor initiation and progression.

AKT1 AKT3 AKT2

9.34e-10335324722238
Pubmed

The AKT genes and their roles in various disorders.

AKT1 AKT3 AKT2

9.34e-10335324039187
Pubmed

Life with a single isoform of Akt: mice lacking Akt2 and Akt3 are viable but display impaired glucose homeostasis and growth deficiencies.

AKT1 AKT3 AKT2

9.34e-10335316923958
Pubmed

Nonredundant role of Akt2 for neuroprotection of rod photoreceptor cells from light-induced cell death.

AKT1 AKT3 AKT2

9.34e-10335317202487
Pubmed

Specific Targeting of Akt Kinase Isoforms: Taking the Precise Path for Prevention and Treatment of Cancer.

AKT1 AKT3 AKT2

9.34e-10335326953242
Pubmed

Identification and quantification of AKT isoforms and phosphoforms in breast cancer using a novel nanofluidic immunoassay.

AKT1 AKT3 AKT2

9.34e-10335323929892
Pubmed

Identifying genotype-dependent efficacy of single and combined PI3K- and MAPK-pathway inhibition in cancer.

AKT1 AKT3 AKT2

9.34e-10335319805051
Pubmed

Signalling specificity in the Akt pathway in breast cancer.

AKT1 AKT3 AKT2

9.34e-10335325233414
Pubmed

Akt2 regulates all Akt isoforms and promotes resistance to hypoxia through induction of miR-21 upon oxygen deprivation.

AKT1 AKT3 AKT2

9.34e-10335321555366
Pubmed

Specific Akt Family Members Impair Stress-Mediated Transactivation of Viral Promoters and Enhance Neuronal Differentiation: Important Functions for Maintaining Latency.

AKT1 AKT3 AKT2

9.34e-10335332796067
Pubmed

All Akt isoforms (Akt1, Akt2, Akt3) are involved in normal hearing, but only Akt2 and Akt3 are involved in auditory hair cell survival in the mammalian inner ear.

AKT1 AKT3 AKT2

9.34e-10335325811375
Pubmed

Akt/Protein kinase B is required for lymphatic network formation, remodeling, and valve development.

AKT1 AKT3 AKT2

9.34e-10335320724596
Pubmed

Akt Regulates Axon Wrapping and Myelin Sheath Thickness in the PNS.

AKT1 AKT3 AKT2

9.34e-10335327098694
Pubmed

Variation in Akt protein kinases in human populations.

AKT1 AKT3 AKT2

9.34e-10335328931550
Pubmed

Cellular survival: a play in three Akts.

AKT1 AKT3 AKT2

9.34e-10335310579998
Pubmed

Key signalling nodes in mammary gland development and cancer. Signalling downstream of PI3 kinase in mammary epithelium: a play in 3 Akts.

AKT1 AKT3 AKT2

9.34e-10335320398329
Pubmed

Isoform-specific roles for AKT in affective behavior, spatial memory, and extinction related to psychiatric disorders.

AKT1 AKT3 AKT2

9.34e-10335333325370
Pubmed

The Akt isoforms are present at distinct subcellular locations.

AKT1 AKT3 AKT2

9.34e-10335320018949
Pubmed

Identification of AKT kinases as unfavorable prognostic factors for hepatocellular carcinoma by a combination of expression profile, interaction network analysis and clinical validation.

AKT1 AKT3 AKT2

9.34e-10335324247267
Pubmed

Dissociation of gemcitabine sensitivity and protein kinase B signaling in pancreatic ductal adenocarcinoma models.

AKT1 AKT3 AKT2

9.34e-10335317895832
Pubmed

Reduction of Akt2 expression inhibits chemotaxis signal transduction in human breast cancer cells.

AKT1 AKT2 PRKCZ

9.34e-10335318353613
Pubmed

Molecular cloning, expression and characterization of the human serine/threonine kinase Akt-3.

AKT1 AKT3 AKT2

9.34e-10335310491192
Pubmed

Akt1 ablation inhibits, whereas Akt2 ablation accelerates, the development of mammary adenocarcinomas in mouse mammary tumor virus (MMTV)-ErbB2/neu and MMTV-polyoma middle T transgenic mice.

AKT1 AKT3 AKT2

9.34e-10335317210696
Pubmed

Role for Akt3/protein kinase Bgamma in attainment of normal brain size.

AKT1 AKT3 AKT2

9.34e-10335315713641
Pubmed

Differentiation of the ductal epithelium and smooth muscle in the prostate gland are regulated by the Notch/PTEN-dependent mechanism.

AKT1 AKT3 AKT2 AR

1.55e-091635421624358
Pubmed

Protein kinase Akt2/PKBβ is involved in blastomere proliferation of preimplantation mouse embryos.

AKT1 AKT3 AKT2

3.73e-09435331552693
Pubmed

PIP3 but not PIP2 increases GLUT4 surface expression and glucose metabolism mediated by AKT/PKCζ/λ phosphorylation in 3T3L1 adipocytes.

AKT1 PRKCI PRKCZ

3.73e-09435323749168
Pubmed

Differential effects of protein kinase B/Akt isoforms on glucose homeostasis and islet mass.

AKT1 AKT3 AKT2

3.73e-09435319933838
Pubmed

Akt1 deletion prevents lung tumorigenesis by mutant K-ras.

AKT1 AKT3 AKT2

3.73e-09435321242979
Pubmed

Melanopsin Phototransduction Is Repurposed by ipRGC Subtypes to Shape the Function of Distinct Visual Circuits.

TRPC7 TRPC3 TRPC6

3.73e-09435330017393
Pubmed

Hydrogen sulfide and L-cysteine increase phosphatidylinositol 3,4,5-trisphosphate (PIP3) and glucose utilization by inhibiting phosphatase and tensin homolog (PTEN) protein and activating phosphoinositide 3-kinase (PI3K)/serine/threonine protein kinase (AKT)/protein kinase Cζ/λ (PKCζ/λ) in 3T3l1 adipocytes.

AKT1 PRKCI PRKCZ

3.73e-09435321953448
Pubmed

Activator protein-1 has an essential role in pancreatic cancer cells and is regulated by a novel Akt-mediated mechanism.

AKT1 AKT3 AKT2

3.73e-09435319435822
Pubmed

Nonredundant functions for Akt isoforms in astrocyte growth and gliomagenesis in an orthotopic transplantation model.

AKT1 AKT3 AKT2

3.73e-09435321507933
Pubmed

Conditional inactivation of Akt three isoforms causes tau hyperphosphorylation in the brain.

AKT1 AKT3 AKT2

3.73e-09435326227811
Pubmed

Casein kinase 2-interacting protein-1, a novel Akt pleckstrin homology domain-interacting protein, down-regulates PI3K/Akt signaling and suppresses tumor growth in vivo.

AKT1 AKT3 AKT2

3.73e-09435317942896
Pubmed

Loss of 2 Akt (Protein Kinase B) Isoforms in Hematopoietic Cells Diminished Monocyte and Macrophage Survival and Reduces Atherosclerosis in Ldl Receptor-Null Mice.

AKT1 AKT3 AKT2

3.73e-09435330567482
Pubmed

Human immunodeficiency virus type 1 induces lytic cycle replication of Kaposi's-sarcoma-associated herpesvirus: role of Ras/c-Raf/MEK1/2, PI3K/AKT, and NF-κB signaling pathways.

AKT1 AKT3 AKT2

3.73e-09435321763505
Pubmed

The E3 ligase TTC3 facilitates ubiquitination and degradation of phosphorylated Akt.

AKT1 AKT3 AKT2

9.32e-09535320059950
Pubmed

Akt1-Inhibitor of DNA binding2 is essential for growth cone formation and axon growth and promotes central nervous system axon regeneration.

AKT1 AKT3 AKT2

9.32e-09535327938661
Pubmed

Intrinsic phototransduction persists in melanopsin-expressing ganglion cells lacking diacylglycerol-sensitive TRPC subunits.

TRPC7 TRPC3 TRPC6

9.32e-09535321261756
Pubmed

PI3K-Akt signaling pathway upregulates hepatitis C virus RNA translation through the activation of SREBPs.

AKT1 AKT3 AKT2

9.32e-09535326855332
Pubmed

Unequal contribution of Akt isoforms in the double-negative to double-positive thymocyte transition.

AKT1 AKT3 AKT2

9.32e-09535317442925
Pubmed

ADP-stimulated activation of Akt during integrin outside-in signaling promotes platelet spreading by inhibiting glycogen synthase kinase-3β.

AKT1 AKT3 AKT2

9.32e-09535322814751
Pubmed

Leptin deficiency and beta-cell dysfunction underlie type 2 diabetes in compound Akt knockout mice.

AKT1 AKT3 AKT2

9.32e-09535319289493
Pubmed

Platelet-derived growth factor protects neurons against gp120-mediated toxicity.

AKT1 AKT3 AKT2

9.32e-09535318300076
Pubmed

TRPC channels are necessary mediators of pathologic cardiac hypertrophy.

TRPC7 TRPC3 TRPC6

9.32e-09535320351294
Pubmed

The activity of the anti-apoptotic fragment generated by the caspase-3/p120 RasGAP stress-sensing module displays strict Akt isoform specificity.

AKT1 AKT3 AKT2

9.32e-09535325246356
Pubmed

Eosinophil major basic protein stimulates neutrophil superoxide production by a class IA phosphoinositide 3-kinase and protein kinase C-zeta-dependent pathway.

AKT1 AKT2 PRKCZ

9.32e-09535314500673
Pubmed

Brown fat organogenesis and maintenance requires AKT1 and AKT2.

AKT1 AKT3 AKT2

9.32e-09535330833219
Pubmed

The deubiquitinase OTUD1 noncanonically suppresses Akt activation through its N-terminal intrinsically disordered region.

AKT1 AKT3 AKT2

9.32e-09535336640312
Pubmed

Spontaneous Hepatocellular Carcinoma after the Combined Deletion of Akt Isoforms.

AKT1 AKT3 AKT2

9.32e-09535326996309
Pubmed

Neutrophil AKT2 regulates heterotypic cell-cell interactions during vascular inflammation.

AKT1 AKT3 AKT2

1.86e-08635324642468
Pubmed

mTORC2-AKT signaling to ATP-citrate lyase drives brown adipogenesis and de novo lipogenesis.

AKT1 AKT3 AKT2

1.86e-08635331996678
Pubmed

KCTD20, a relative of BTBD10, is a positive regulator of Akt.

AKT1 AKT3 AKT2

1.86e-08635324156551
Pubmed

fgf8 mRNA decay establishes a gradient that couples axial elongation to patterning in the vertebrate embryo.

AKT1 AKT3 AKT2

1.86e-08635314749824
Pubmed

HIV-1 Nef mediates Pak phosphorylation of Mek1 serine298 and elicits an active phospho-state of Pak2.

AKT1 AKT3 AKT2

1.86e-08635323746211
Pubmed

Akt forms an intracellular complex with heat shock protein 90 (Hsp90) and Cdc37 and is destabilized by inhibitors of Hsp90 function.

AKT1 AKT3 AKT2

1.86e-08635312176997
Pubmed

Stabilization of phosphofructokinase 1 platelet isoform by AKT promotes tumorigenesis.

AKT1 AKT3 AKT2

1.86e-08635329038421
Pubmed

Expression of CX3CR1 chemokine receptors on neurons and their role in neuronal survival.

AKT1 AKT3 AKT2

1.86e-08635310869418
Pubmed

Akt Regulates Sox10 Expression to Control Oligodendrocyte Differentiation via Phosphorylating FoxO1.

AKT1 AKT3 AKT2

1.86e-08635334385359
Pubmed

HIV-1 accessory protein Vpr inhibits the effect of insulin on the Foxo subfamily of forkhead transcription factors by interfering with their binding to 14-3-3 proteins: potential clinical implications regarding the insulin resistance of HIV-1-infected patients.

AKT1 AKT3 AKT2

1.86e-08635315616007
Pubmed

Insulin receptor signaling in cones.

AKT1 AKT3 AKT2

1.86e-08635323673657
Pubmed

The prognostic impact of Akt isoforms, PI3K and PTEN related to female steroid hormone receptors in soft tissue sarcomas.

AKT1 AKT3 AKT2

1.86e-08635322107784
Pubmed

Differential regulation of Akt kinase isoforms by the members of the TCL1 oncogene family.

AKT1 AKT3 AKT2

1.86e-08635311707444
Pubmed

Nef inhibits glucose uptake in adipocytes and contributes to insulin resistance in human immunodeficiency virus type I infection.

AKT1 AKT3 AKT2

1.86e-08635321606541
Pubmed

Protein kinase B alpha/Akt1 regulates placental development and fetal growth.

AKT1 AKT3 AKT2

1.86e-08635312783884
Pubmed

A novel Akt/PKB-interacting protein promotes cell adhesion and inhibits familial amyotrophic lateral sclerosis-linked mutant SOD1-induced neuronal death via inhibition of PP2A-mediated dephosphorylation of Akt/PKB.

AKT1 AKT3 AKT2

1.86e-08635318160256
Pubmed

AKT-dependent HspB1 (Hsp27) activity in epidermal differentiation.

AKT1 AKT3 AKT2

1.86e-08635317439945
Pubmed

Mutational and immunohistochemical study of the PI3K/Akt pathway in papillary thyroid carcinoma in Greece.

AKT1 AKT3 AKT2

1.86e-08635320186503
Pubmed

Integrin linked kinase (ILK) is required for lens epithelial cell survival, proliferation and differentiation.

AKT1 AKT3 AKT2 PTK2

2.31e-083035424472646
Pubmed

MxA, a member of the dynamin superfamily, interacts with the ankyrin-like repeat domain of TRPC.

TRPC7 TRPC3 TRPC6

3.26e-08735315757897
Pubmed

Dynamics of Akt activation during mouse embryo development: distinct subcellular patterns distinguish proliferating versus differentiating cells.

AKT1 AKT3 AKT2

3.26e-08735323968884
Pubmed

Depletion of Pleckstrin homology domain leucine-rich repeat protein phosphatases 1 and 2 by Bcr-Abl promotes chronic myelogenous leukemia cell proliferation through continuous phosphorylation of Akt isoforms.

AKT1 AKT3 AKT2

3.26e-08735319261608
Pubmed

Synergy between Kaposi's sarcoma-associated herpesvirus (KSHV) vIL-6 and HIV-1 Nef protein in promotion of angiogenesis and oncogenesis: role of the AKT signaling pathway.

AKT1 AKT3 AKT2

3.26e-08735323604117
Pubmed

TRPC absence induces pro-inflammatory macrophages and gut microbe disorder, sensitizing mice to colitis.

TRPC7 TRPC3 TRPC6

3.26e-08735336592529
Pubmed

Functional role of TRPC proteins in vivo: lessons from TRPC-deficient mouse models.

TRPC7 TRPC3 TRPC6

3.26e-08735315336983
Pubmed

Ginsenoside Rh1 eliminates the cytoprotective phenotype of human immunodeficiency virus type 1-transduced human macrophages by inhibiting the phosphorylation of pyruvate dehydrogenase lipoamide kinase isozyme 1.

AKT1 AKT3 AKT2

3.26e-08735323811558
Pubmed

Direct evidence for the action of phosphatidylinositol (3,4,5)-trisphosphate-mediated signal transduction in the 2-cell mouse embryo.

AKT1 AKT3 AKT2

3.26e-08735317634444
Pubmed

Dosage-dependent effects of Akt1/protein kinase Balpha (PKBalpha) and Akt3/PKBgamma on thymus, skin, and cardiovascular and nervous system development in mice.

AKT1 AKT3 AKT2

3.26e-08735316287854
Pubmed

Inhibition of HIV-1 Tat-mediated transcription by a coumarin derivative, BPRHIV001, through the Akt pathway.

AKT1 AKT3 AKT2

3.26e-08735321697490
Pubmed

RNA-seq analysis reveals TRPC genes to impact an unexpected number of metabolic and regulatory pathways.

TRPC7 TRPC3 TRPC6

3.26e-08735332350291
InteractionTRPC7 interactions

TRPC7 TRPC3 TRPC6

7.97e-086333int:TRPC7
InteractionAKT1S1 interactions

AKT1 AKT3 AKT2 ESR2

2.07e-0732334int:AKT1S1
InteractionMX1 interactions

TRPC7 ESR2 TRPC3 TRPC6

2.72e-0660334int:MX1
InteractionRPS6KB1 interactions

AKT1 AKT3 AKT2 PRKCZ ESR2

3.39e-06143335int:RPS6KB1
InteractionBTBD10 interactions

AKT1 AKT3 AKT2

6.03e-0622333int:BTBD10
InteractionTMPRSS12 interactions

NPC1 SLC47A1 ZMPSTE24

6.93e-0623333int:TMPRSS12
InteractionGNB1 interactions

AKT1 PRKCI AKT2 AR PTK2 ESR2

9.32e-06307336int:GNB1
InteractionAKT3 interactions

AKT1 AKT3 AKT2 PRKCZ

1.10e-0585334int:AKT3
InteractionPDPK1 interactions

AKT1 PRKCI AKT3 AKT2 PRKCZ

1.86e-05203335int:PDPK1
InteractionTRPC3 interactions

TRPC7 TRPC3 TRPC6

2.11e-0533333int:TRPC3
InteractionEIF4A1 interactions

AKT1 RPSA TMEM43 PRKCZ AR ESR2

2.12e-05355336int:EIF4A1
InteractionITPR3 interactions

AKT1 TRPC7 ESR2 TRPC3 TRPC6

2.24e-05211335int:ITPR3
InteractionGSN interactions

AKT3 PRKCZ AR PTK2 ESR2

2.29e-05212335int:GSN
InteractionMTCP1 interactions

AKT1 AKT2

3.88e-056332int:MTCP1
InteractionCD44 interactions

NPC1 AKT1 PRKCI AKT3 PRKCZ

4.07e-05239335int:CD44
InteractionTFF1 interactions

AKT1 PRKCZ ESR2

4.09e-0541333int:TFF1
InteractionSGK2 interactions

AKT1 AKT3 AKT2

4.72e-0543333int:SGK2
InteractionTTC3 interactions

AKT1 AKT3 AKT2 ESR2

4.87e-05124334int:TTC3
InteractionAKT1 interactions

AKT1 AKT3 AKT2 PRKCZ AR PTK2 ESR2

5.20e-05617337int:AKT1
InteractionEMC1 interactions

NPC1 TMEM43 ZMPSTE24 EPHA10 ESR2 TRPC6

5.29e-05418336int:EMC1
InteractionTPM4 interactions

NPC1 AKT1 AKT3 AR ESR2

5.96e-05259335int:TPM4
InteractionCDC37 interactions

AKT1 PRKCI AKT3 AKT2 PRKCZ AR PTK2

6.88e-05645337int:CDC37
InteractionMME interactions

ZMPSTE24 AR PTK2 ESR2

7.38e-05138334int:MME
InteractionITPR1 interactions

GRID2 AKT1 TRPC3 TRPC6

8.02e-05141334int:ITPR1
InteractionSRC interactions

AKT1 PRKCI PRKCZ AR PTK2 ESR2 TRPC6

8.26e-05664337int:SRC
InteractionAKT2 interactions

AKT1 AKT3 AKT2 PRKCZ

8.48e-05143334int:AKT2
InteractionSEL1L interactions

NPC1 EPHA10 ESR2 TRPC6

8.94e-05145334int:SEL1L
InteractionIRS1 interactions

AKT1 PRKCZ PTK2 ESR2

8.94e-05145334int:IRS1
InteractionPFKP interactions

AKT1 AKT3 AKT2 PRKCZ ESR2

9.22e-05284335int:PFKP
InteractionSHANK2 interactions

GRID2 AKT1 ESR2

9.90e-0555333int:SHANK2
InteractionPPP1CB interactions

NPC1 AKT1 PRKCI AR PTK2 ESR2

9.99e-05469336int:PPP1CB
InteractionSTEAP4 interactions

NPC1 AKT2

1.16e-0410332int:STEAP4
InteractionRPE interactions

AKT1 AKT3 AKT2

1.16e-0458333int:RPE
InteractionCSNK2A1 interactions

NPC1 AKT1 PRKCI RPSA PRKCZ AR PTK2 ESR2

1.20e-04956338int:CSNK2A1
InteractionTRIB3 interactions

AKT1 AKT2 RPSA AR

1.31e-04160334int:TRIB3
InteractionNIPSNAP2 interactions

NPC1 PRKCI PRKCZ ESR2

1.34e-04161334int:NIPSNAP2
InteractionAFAP1 interactions

AKT3 PRKCZ ESR2

1.35e-0461333int:AFAP1
InteractionTCL1A interactions

AKT1 AKT3 AKT2

1.35e-0461333int:TCL1A
InteractionCD55 interactions

NPC1 ZMPSTE24 ESR2

1.42e-0462333int:CD55
InteractionHSP90AA1 interactions

AKT1 PRKCI AKT3 AKT2 RPSA PRKCZ AR PTK2 ESR2

1.42e-041263339int:HSP90AA1
InteractionOTUD1 interactions

AKT1 AKT3 AKT2 RPSA

1.65e-04170334int:OTUD1
InteractionPRKG1 interactions

AR PTK2 TRPC3

1.78e-0467333int:PRKG1
InteractionAPPL1 interactions

AKT1 AKT2 PRKCZ AR

2.15e-04182334int:APPL1
InteractionPIAS1 interactions

AKT1 RPSA AR PTK2 ESR2

2.54e-04353335int:PIAS1
InteractionVHL interactions

AKT1 PRKCI AKT2 RPSA PRKCZ AR

2.64e-04561336int:VHL
InteractionSP1 interactions

AKT1 RPSA PRKCZ AR ESR2

2.96e-04365335int:SP1
InteractionTRPC6 interactions

TRPC7 TRPC3 TRPC6

3.24e-0482333int:TRPC6
InteractionDDOST interactions

NPC1 TMEM43 PRKCZ ZMPSTE24 ESR2

3.36e-04375335int:DDOST
InteractionPLEKHO1 interactions

AKT1 AKT3 AKT2

3.48e-0484333int:PLEKHO1
InteractionSP3 interactions

AKT1 ESR2 TRPC6

3.48e-0484333int:SP3
InteractionCLIP3 interactions

AKT1 AKT2

3.48e-0417332int:CLIP3
InteractionBLVRA interactions

AKT1 AKT2 PRKCZ

3.73e-0486333int:BLVRA
InteractionCASP3 interactions

AKT1 AKT3 PRKCZ AR

4.12e-04216334int:CASP3
InteractionDAPK3 interactions

PRKCZ AR ESR2

4.13e-0489333int:DAPK3
InteractionRNH1 interactions

NPC1 PRKCI PRKCZ ESR2

4.41e-04220334int:RNH1
InteractionCAMK2D interactions

AKT1 PTK2 EPHA10 ESR2

4.56e-04222334int:CAMK2D
InteractionCCNT1 interactions

PRKCI RPSA AR ESR2

4.80e-04225334int:CCNT1
InteractionFARP2 interactions

PRKCI PRKCZ ESR2

4.84e-0494333int:FARP2
InteractionEIF4EBP1 interactions

AKT1 AKT3 AKT2

4.84e-0494333int:EIF4EBP1
InteractionRPS6KA1 interactions

AKT1 AKT3 AKT2 AR

5.05e-04228334int:RPS6KA1
InteractionEMC2 interactions

NPC1 TMEM43 ZMPSTE24 ESR2 TRPC6

5.10e-04411335int:EMC2
InteractionPRKCZ interactions

AKT1 PRKCI AKT3 AKT2 PRKCZ

5.16e-04412335int:PRKCZ
InteractionFKBP5 interactions

AKT1 AKT3 AKT2 AR PTK2

5.27e-04414335int:FKBP5
InteractionKCTD20 interactions

AKT1 AKT2

5.36e-0421332int:KCTD20
InteractionGRID2 interactions

GRID1 GRID2

5.88e-0422332int:GRID2
InteractionGRID1 interactions

GRID1 GRID2

5.88e-0422332int:GRID1
InteractionFYN interactions

NPC1 PRKCI PRKCZ PTK2 TRPC6

6.33e-04431335int:FYN
InteractionPNRC1 interactions

AR ESR2

6.44e-0423332int:PNRC1
InteractionTRPC4 interactions

TRPC3 TRPC6

6.44e-0423332int:TRPC4
InteractionLMAN2 interactions

NPC1 AKT2 ESR2

6.69e-04105333int:LMAN2
InteractionSLC2A1 interactions

NPC1 BTAF1 TMEM43 ESR2

6.81e-04247334int:SLC2A1
InteractionTRPC5 interactions

TRPC3 TRPC6

7.02e-0424332int:TRPC5
InteractionPSMD1 interactions

PRKCI RPSA PRKCZ AR ESR2

7.09e-04442335int:PSMD1
InteractionMAP4K4 interactions

AKT1 AKT3 AKT2 PTK2

7.56e-04254334int:MAP4K4
InteractionGRHL2 interactions

AR ESR2

7.62e-0425332int:GRHL2
InteractionFAF2 interactions

NPC1 TMEM43 AR EPHA10 ESR2

7.77e-04451335int:FAF2
InteractionTYSND1 interactions

AR ESR2

8.25e-0426332int:TYSND1
InteractionFKBP1A interactions

TRPC7 TRPC3 TRPC6

8.28e-04113333int:FKBP1A
InteractionTPM1 interactions

NPC1 AKT3 AR ESR2

8.61e-04263334int:TPM1
InteractionPLCG1 interactions

AKT1 AR PTK2 TRPC3

8.73e-04264334int:PLCG1
GeneFamilyGlutamate ionotropic receptor delta type subunits

GRID1 GRID2

1.28e-0622121202
GeneFamilyTransient receptor potential cation channels

TRPC7 TRPC3 TRPC6

4.34e-0628213249
GeneFamilyNuclear hormone receptors

AR ESR2

1.46e-034921271
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

AKT1 AKT3 AKT2

1.67e-03206213682
ToppCelldroplet-Lung-LUNG-30m-Mesenchymal-pericyte_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STUM PTK2 TRPC3 TRPC6

1.15e-05179354bfc226bcf0b93525992344f968268a261d86fcbf
ToppCelldroplet-Lung-LUNG-30m-Mesenchymal-Pericyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STUM PTK2 TRPC3 TRPC6

1.15e-0517935436ad18f52e175ab636ceaa3be81212fa362c96c1
ToppCelltumor_Lung-Fibroblasts-Pericytes|Fibroblasts / Location, Cell class and cell subclass

GRID1 PTK2 TRPC3 TRPC6

1.43e-051893549c407b17d7945e81e1ae6c18452f5d20fb09d563
ToppCellParenchymal-NucSeq-Stromal-Pericyte|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

GRID1 AKT3 TRPC3 TRPC6

1.68e-0519735441dd312f46a2b983c8d864adeb6970c0ca4a8048
ToppCellParenchymal-NucSeq-Stromal-Pericyte-Muscle_pericyte_pulmonary|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

GRID1 AKT3 TRPC3 TRPC6

1.68e-05197354f66945f9007d59d4208849c7fd727f8519713fbc
ToppCellmild-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

NPC1 AKT3 BTAF1 RTTN

1.75e-05199354f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCellLPS_only-Unknown|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SLC9C1 TRPC3 TRPC6

1.00e-041153537a733f6987b40ec497a03734b79ed5355ad3a2fc
ToppCellLPS_only-Unknown-Endothelial-Pericyte_2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SLC9C1 TRPC3 TRPC6

1.00e-04115353c67145d3cd9243994a141749b426ff2a6dcc8d93
ToppCellLPS_only-Unknown-Endothelial|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SLC9C1 TRPC3 TRPC6

1.00e-04115353ad5298c2ad8bf94fa13c2e50b0799e929473ef59
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_ALM_Tmem163_Arhgap25|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

STUM TRPC7 TRPC3

1.06e-04117353e1a14b8413a6f4b194217a90eb2c5f95ab14522e
ToppCellEnterocyte-C_02|Enterocyte / shred on cell type and cluster

RPSA PGGHG KCNJ13

1.65e-04136353daf11618c65e8fa2d77001b5c277d534cc012a4b
ToppCellTCGA-Uvea|World / Sample_Type by Project: Shred V9

PNMA6A KCNJ13 RTTN

1.83e-04141353015451a83087f2705d3315ebc8f23797c6f10ed6
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

GRID1 GRID2 TRPC3

2.38e-04154353b6e982e341c6cfb6ff80a318078fcb10c36d182f
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

GRID1 GRID2 TRPC3

2.38e-04154353d76fd51a4587decbfe1dde1c8a9b880c5fa18e4a
ToppCell5'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-EC_cells_(NPW+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TRPC7 ABCA9 EPHA10

2.42e-04155353498e52e2364ff44d3c0c707ba22468217031f5bd
ToppCell390C-Myeloid-Macrophage-SPP1+_Macrophage_2|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

AACS PRKCI AR

2.66e-041603538aaf6ac4f33ea291387fdbf9ff1a91d559391774
ToppCellE16.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GRID2 TMEM117 KCNJ13

2.86e-04164353b6beb8548ac0dd07e8a580a938e5ee4bf25a3c1f
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW16-Mesenchymal-Cilia-bearing_cell|GW16 / Sample Type, Dataset, Time_group, and Cell type.

NPC1 SPTSSA KCNJ13

2.86e-04164353346e1530b4bf30adbcb2f7d64fdfb4cd8df69d7f
ToppCellE16.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2-AT1/AT2_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GRID2 TMEM117 KCNJ13

2.86e-04164353fe11fcce4ba7f44ba2989ea3705916b67e75f8e7
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

GRID1 GRID2 TRPC6

2.91e-04165353cd8de98af8a1a8a6c81d71fae807cc07f319f4c9
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

GRID1 GRID2 TRPC6

2.91e-041653534f83ac71efc57be3668d8db1e62bad05dc6a5e2b
ToppCellfacs-Marrow-T-cells-3m-Hematologic-MPP_Fraction_B_+_C|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STUM AR PTK2

3.17e-04170353d70aaa0f4e5034bb9f61b832b5f9123870936d3c
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

AKT2 PGGHG ESR2

3.17e-041703535d5f208682be21ed58320f5fc083a7898f8712da
ToppCellControl-Fibroblasts-Pericytes|Control / group, cell type (main and fine annotations)

GRID1 TRPC3 TRPC6

3.23e-04171353080003f698f867935c2bfc55d241d3650f45a0ab
ToppCellPND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PTK2 TRPC3 TRPC6

3.28e-0417235303a0aff6b7971093a4347b5ed12546d78374c56f
ToppCellAdult-Mesenchymal-pericyte_cell-D175|Adult / Lineage, Cell type, age group and donor

GRID1 TRPC3 TRPC6

3.34e-04173353fd6653d6be9ca6ac36798590694efe03cb758c67
ToppCellfacs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l20-1|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GRID1 AKT2 PGGHG

3.40e-041743531d157f7a919c8246e83d8060d2a0017c6c781ef3
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GRID1 GRID2 TRPC3

3.45e-04175353d52794426f2703a80e91ae0a8ff2d8e0ce4aa4a8
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GRID1 GRID2 TRPC3

3.45e-04175353454f03e6109d65f5db08dbb41ecc19ffb6bbc4e0
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

STUM TMEM117 KCNJ13

3.51e-04176353cb21342dd135cc80a50aafe7bf8bf31265db68dd
ToppCelldroplet-Lung-3m-Mesenchymal-myofibroblast-pericyte_cell-pericyte|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PTK2 TRPC3 TRPC6

3.51e-04176353e2b59a904c5c8f9c88e1e63788e9b6485f22edd0
ToppCelldroplet-Lung-3m-Mesenchymal-myofibroblast-pericyte_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PTK2 TRPC3 TRPC6

3.51e-04176353f931192e3cc65414e2245354f443473696cc7ce8
ToppCellBAL-Control-Lymphocyte-B|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

STUM ESR2 TMEM117

3.51e-041763537c1ecec45b5fe5e73cbce0fadca726ffd10c0316
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GRID1 GRID2 TRPC6

3.57e-041773534943d040eee0f9dceaddc7498171281d170e271f
ToppCellfacs-Heart-LA-24m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STUM EPHA10 TRPC6

3.57e-041773531b153fbfe1323dc589de4af73a52149ea5ce6763
ToppCelldroplet-Lung-nan-3m-Mesenchymal-pericyte_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTK2 TRPC3 TRPC6

3.57e-0417735365709bd546cb1ec6aa2ddd8b2adb46e174eb9a9a
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GRID1 GRID2 TRPC6

3.57e-041773533f2272b577c862dba8ccfb41184054bbd0ace6f5
ToppCellfacs-Heart-LA-24m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STUM EPHA10 TRPC6

3.57e-0417735332fecefba1a55e1f418c9a055236fa11175c692d
ToppCelldroplet-Lung-nan-3m-Mesenchymal-Pericyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTK2 TRPC3 TRPC6

3.57e-041773538684d47a547e2a06496f15e8da0200ecddc431e0
ToppCelldroplet-Heart-nan-3m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STUM TRPC3 TRPC6

3.57e-04177353dbdbdc8ed9ef0b529694242ef9f9f07a42e16005
ToppCellChildren_(3_yrs)-Mesenchymal-pericyte_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

GRID1 TRPC3 TRPC6

3.63e-04178353185b44700f06ec58b3c09c80520502166c965fd6
ToppCellChildren_(3_yrs)-Epithelial-basal_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

AR PTK2 TRPC6

3.63e-04178353fba2e38c05cbf031e0c6d47b1602575fea734a57
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NPC1 STUM TMEM117

3.69e-04179353e6ae070b4c52ba08167c7d64ea4cfbac0454c1bf
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Mesenchymal-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NPC1 PRKCZ TRPC3

3.69e-04179353e880c507f11ce75d104593a4ca29f0295f8125e8
ToppCelldroplet-Lung-18m-Mesenchymal-myofibroblast-pericyte_cell-pericyte|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LY6G6F TRPC3 TRPC6

3.69e-04179353fa03ec3cc0132f977b4cb28e7b23789732375183
ToppCelldroplet-Lung-18m-Mesenchymal-myofibroblast-pericyte_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LY6G6F TRPC3 TRPC6

3.69e-04179353f5bb4d3a27d56698473219970e764084096cc582
ToppCellrenal_papilla_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

SLC9C1 PGGHG ESR2

3.75e-0418035349829e833fe6d2431cfd2e8f378c2aaa3b2b46a4
ToppCelldroplet-Lung-nan-18m-Mesenchymal-Pericyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LY6G6F TRPC3 TRPC6

3.75e-04180353f6a05b3751b01e74b2de8440801b0eb2e723c199
ToppCelldroplet-Lung-nan-18m-Mesenchymal-pericyte_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LY6G6F TRPC3 TRPC6

3.75e-04180353dfc75ae4395ff46fbec2c54915d98ead5a1ba1a1
ToppCelldroplet-Heart-nan-24m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STUM TRPC3 TRPC6

3.75e-0418035378fdcfb3fdbf36469cae78407cda5bd0996930d8
ToppCellChildren_(3_yrs)-Mesenchymal-pericyte_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

GRID1 TRPC3 TRPC6

3.81e-04181353451b87ac95154bb80018b8dd245b4a6389d81411
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GRID1 ABCA9 TRPC3

3.87e-04182353af65f0fc3f9e5d9ce69ee5faaf5b6cb7f8412e0c
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GRID1 ABCA9 TRPC3

3.87e-04182353b7d532feb73167e05475855061b35a209583f44c
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC47A1 ACMSD RTTN

3.94e-04183353facd6dbe0851b537d70a899ac7485714ab27d071
ToppCellNS-critical-d_07-13-Epithelial-Ionocyte|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

STUM PNMA6A AR

3.94e-04183353ba43bca2b45be1008eebd3f033cecb061fb3a966
ToppCell10x5'v1-week_17-19-Hematopoietic-MK-MK|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

LY6G6F STUM TRPC6

3.94e-041833539c66a40c355387f805dbdca4162dd05af5c1d8d4
ToppCellfacs-Lung-EPCAM-24m-Mesenchymal-Pericyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STUM TRPC6 RTTN

3.94e-041833530e8fb371d8eac777451c76f41d53577f5dfb740d
ToppCelltumor_Lung-Fibroblasts-Pericytes|tumor_Lung / Location, Cell class and cell subclass

GRID1 TRPC3 TRPC6

3.94e-04183353a03dd563af9b15cb1f5de5732a229405a9f82d84
ToppCellfacs-Lung-EPCAM-24m-Mesenchymal-pericyte_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STUM TRPC6 RTTN

3.94e-04183353cbc3b00faa7e4e0dbbbc8ee105467c65241c7470
ToppCell5'-GW_trimst-2-LymphNode-Mesenchymal-fibroblastic-Stromal_3_(C7+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GRID2 TMEM43 ABCA9

4.00e-041843534d4d8f3f44c67d74c57e7af7b7c158f0157b2f49
ToppCellmegakaryocytic|World / Lineage and Cell class

LY6G6F STUM TRPC6

4.00e-04184353b1c630ca2189d9d49402a5621b57618976fbea5c
ToppCelldroplet-Heart-nan-24m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STUM TRPC3 TRPC6

4.00e-04184353f4344f3c407b2d4d703fe56e43d84dbfe60ba833
ToppCellCOVID-19-Fibroblasts-Pericytes|COVID-19 / group, cell type (main and fine annotations)

GRID1 TRPC3 TRPC6

4.06e-041853534905adaeeffd353e089578e5ea614437dbe794e6
ToppCellCOVID-19-Endothelial_cells-Systemic_venous_endothelial_cells|COVID-19 / group, cell type (main and fine annotations)

AKT3 PTK2 ESR2

4.06e-04185353f5e14181f45c37d13ee9e017a4c8bc248c353676
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L5-6_SST_ISOC1|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SLC47A1 GRID2 TRPC6

4.06e-04185353ae53aa2ecfe418a5dbd7d963a995bc06dab94f56
ToppCellFetal_29-31_weeks-Mesenchymal-pericyte_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

GRID1 TRPC3 TRPC6

4.06e-04185353a7dba7db79275884b2a93d8a16f2e0c739e71370
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Degenerative_Cortical_Intercalated_Cell_Type_A|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NPC1 STUM TMEM117

4.06e-041853539438097e94219c1db922b8507e3a29106d32a923
ToppCell(5)_Pericytes|World / Cell class and subclass of bone marrow stroma cells in homeostatis

STUM TRPC3 TRPC6

4.13e-04186353acbca8cc048d87faf859b3e77bdb38d0a3dad71c
ToppCell(5)_Pericytes-(50)_Pericytes|World / Cell class and subclass of bone marrow stroma cells in homeostatis

STUM TRPC3 TRPC6

4.13e-0418635367b59defdd1ed3608229cc5e2a3b480d92312afa
ToppCellAnterior_Cingulate_gyrus_(CgG)|World / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GRID2 STUM TRPC6

4.13e-0418635332af3f211f9ad5d5c6b86b83325cfbf2f8466b56
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SLC47A1 GRID2 TRPC6

4.19e-0418735385f1678338a47d91e296f0620d4887f057eb7e70
ToppCellFetal_29-31_weeks-Mesenchymal-pericyte_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

GRID1 TRPC3 TRPC6

4.19e-04187353fa01a61bfd13feb033ba1e35cf513707b1bff8c8
ToppCellChildren_(3_yrs)-Mesenchymal-pericyte_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

GRID1 TRPC3 TRPC6

4.19e-0418735386250acf088ec0c4800a0dfa031b0d4f7e52c342
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GRID1 GRID2 TRPC6

4.19e-04187353530e4e6d91b5c0d9aa4543caa2b734a1674c5788
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GRID1 GRID2 TRPC6

4.19e-04187353ec4b694487cc446999c7b27b119950a4f252c4b3
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

GRID1 GRID2 TRPC6

4.19e-04187353958402fcc78f4c7a7d13d659d776f3817137975f
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

GRID1 GRID2 TRPC6

4.19e-0418735348bfdb3504c3fefe5db3abac4b790c369680ab4e
ToppCellFetal_29-31_weeks-Mesenchymal-pericyte_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

GRID1 TRPC3 TRPC6

4.19e-04187353a2bf958ea59c359a265bfa437d59315e1920cdd4
ToppCellControl-Fibroblasts-Alveolar_FB|Control / group, cell type (main and fine annotations)

GRID2 ABCA9 TRPC6

4.19e-0418735392d468dde81125d51daf7abd4703741abe1ab91c
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

NPC1 SLC9C1 PRKCZ

4.26e-0418835343a3a59f92ad93509d4166bd025aed0b1b39a008
ToppCellChildren_(3_yrs)-Mesenchymal-pericyte_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

GRID1 TRPC3 TRPC6

4.26e-04188353ee151792c7ac9afe820f1a281c6dab383799f358
ToppCellFetal_29-31_weeks-Mesenchymal-pericyte_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

GRID1 TRPC3 TRPC6

4.26e-04188353ccddc08121caff958a2b6f9e278a018858af6b4d
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

STUM PTK2 TRPC6

4.26e-04188353c2321a3a1d9603f8b4b4fc09707eb32ec1e04f3f
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

GRID1 GRID2 TRPC6

4.33e-04189353fac5c291a9a87418bb0878c3d624829bdbf1f428
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SLC47A1 ACMSD AR

4.33e-0418935328b502611829e4a24caff2562545c7db97686099
ToppCellMesenchymal-pericyte_cell|World / Lineage, Cell type, age group and donor

GRID1 TRPC3 TRPC6

4.33e-04189353d7ed96add29f219183c802895fbff519b627f635
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC47A1 ACMSD AR

4.33e-041893533b48b0d220cc24d5170713d61fa91f5bb6c21841
ToppCellCOVID-19-kidney-PCT-S2|kidney / Disease (COVID-19 only), tissue and cell type

SLC47A1 ACMSD AR

4.33e-041893530be5c669b6b308bd98ddb70c84877c62a6244bbd
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GRID2 TRPC3 TRPC6

4.33e-041893537ab1cfc1657277858339f7258a0c4ae9cb42fdf8
ToppCellmegakaryocytic-CD34+_Megakaryoblast|World / Lineage and Cell class

LY6G6F STUM TRPC6

4.39e-041903531d19b2bd55789bf13e1386332f46c605973d6f8e
ToppCellnucseq-Mesenchymal-Myocytic-Myocytic_1-Pericyte|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

GRID1 TRPC3 TRPC6

4.39e-041903534eb92aef1ee868f4537483d19014d947b7684612
ToppCellnucseq-Mesenchymal-Myocytic-Myocytic_1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

GRID1 TRPC3 TRPC6

4.39e-041903537be4341e2909101d756f14031c21e705eb45e69a
ToppCellPND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PTK2 TRPC3 TRPC6

4.39e-0419035310b02c62e72bfea9767e3e751011436925da823e
ToppCellEpithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|World / Lineage, Cell type, age group and donor

PRKCI SLC9C1 PRKCZ

4.46e-04191353d3733c8c4bda70c4390e5601fdda6188a64be944
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-Stroma____kidney_mesangial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STUM TRPC3 TRPC6

4.46e-041913538597a8af294f24496c317d995f07eb5dcc25c13c
ToppCelldroplet-Heart-HEART-1m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STUM TRPC3 TRPC6

4.46e-041913535c1f5b6c115b1b27b4a7467a6550ce43c01cf6d0
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GRID1 GRID2 TRPC6

4.46e-041913537b0d42a877540dbb346a76a62403e0d5d3e07fa6
ToppCellLPS_only-Stromal_mesenchymal-Lung_smooth_muscle|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GRID2 TRPC3 TRPC6

4.46e-0419135308042952431ca1a6fd7dfc13f36eb28643979598
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GRID1 GRID2 TRPC6

4.46e-04191353cd854b9c426924fdc84bf7f411f6dea447143e79
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GRID1 GRID2 TRPC6

4.53e-0419235324e2f15f5767a97eb3b389922bcfd7b13805e1ce
DrugAkt inhibitor IV

AKT1 AKT3 AKT2 PTK2

4.31e-0824344CID002326992
Drugtriphosphoinositide

AKT1 PRKCI PRKCZ PTK2 TRPC3 TRPC6 KCNJ13

1.35e-07273347CID009543520
DrugGoserelin

NPC1 AR ESR2 TRPC6

4.04e-0741344CID000047725
Drug4-HT

AKT1 AKT3 AKT2 ESR2 TRPC6

4.74e-07105345CID005284643
DrugMMEA

AKT1 AKT2 PTK2

4.98e-0711343CID000125823
Drugsodium

SLC47A1 GRID1 GRID2 AKT1 PRKCI RPSA PRKCZ TRPC3 TRPC6 KCNJ13

7.57e-079443410CID000000923
DrugPKI166

AKT1 AR PTK2 ESR2

7.70e-0748344CID006918403
DrugLY294002

AKT1 PRKCI AKT3 AKT2 PRKCZ AR PTK2 ESR2 TRPC6

1.07e-06748349CID000003973
Drug2-aminoethyl diphenylborinate

AKT1 PRKCI TRPC7 TRPC3 TRPC6

1.22e-06127345CID000001598
Drug1-oleoyl-2-acetylglycerol

TRPC7 TRPC3 TRPC6

1.37e-0615343ctd:C038237
Drugbufalin

AKT1 RPSA AR PTK2

2.04e-0661344ctd:C022777
DrugDEAP-C16Y peptide

AKT1 PTK2

2.16e-062342ctd:C000609387
Drugbarium

PRKCI PRKCZ TRPC3 TRPC6 KCNJ13

2.59e-06148345CID000104810
DrugML 9

AKT3 TRPC7 TRPC6

2.90e-0619343ctd:C056218
Drugstrontium

PRKCI PRKCZ TRPC3 TRPC6

3.15e-0668344CID000104798
Drugdecanamide

AKT1 PRKCI AKT3 AKT2 ESR2

3.92e-06161345CID000075347
Drug4,4'-bisphenol F

AKT1 AKT3 AR ESR2

4.93e-0676344ctd:C008745
Drugmangrove

AACS NPC1 AKT1 PRKCI PRKCZ ACMSD ZMPSTE24

4.93e-06468347CID000000965
DrugAC1L1BDQ

PRKCI PRKCZ TRPC7 TRPC3 TRPC6

5.56e-06173345CID000001394
DrugClenbuterol

AKT1 AKT3 AKT2

6.03e-0624343ctd:D002976
Drug2-(((3,5-dichlorophenyl)carbamoyl)oxy)-2-methyl-3-butenoic acid

AR ESR2

6.49e-063342ctd:C101851
DrugNafoxidine

AR ESR2

6.49e-063342ctd:D009256
Drugp-tert-amylphenol

AR ESR2

6.49e-063342ctd:C019566
DrugChromans

AR ESR2

6.49e-063342ctd:D002839
Drug2,4,6-trichlorophenyl-4'-aminophenyl ether

AR ESR2

6.49e-063342ctd:C067259
Drug4-hydroxybenzophenone

AR ESR2

6.49e-063342ctd:C024292
Drugversalide

AR ESR2

6.49e-063342ctd:C023054
Drugirilone

AR ESR2

6.49e-063342ctd:C530234
Drugundecan-2-one

AR ESR2

6.49e-063342ctd:C526928
Drug2,2',4,4',5-brominated diphenyl ether

AKT1 AR ESR2

7.73e-0626343ctd:C477694
Drugglutamate

GRID1 GRID2 AKT1 PRKCI PRKCZ TRPC7 PTK2 TRPC3 TRPC6

8.35e-06962349CID000000611
DrugAC1OAGKW

AKT1 AKT3 AKT2 PRKCZ PTK2

9.47e-06193345CID006857413
Drug4-hydroxyestradiol

AKT1 AR ESR2

9.72e-0628343ctd:C014036
DrugAC1L1J0H

AKT1 PRKCI RPSA PTK2 ESR2

1.05e-05197345CID000004813
DrugAC1OAGKB

AKT1 AKT3 AKT2 PRKCZ PTK2

1.07e-05198345CID006857406
Drug1,3-DCG

PRKCI PRKCZ TRPC3 TRPC6

1.15e-0594344CID000150911
DrugAC1OAGFB

AKT1 PRKCI PRKCZ PTK2 TRPC3 TRPC6 KCNJ13

1.24e-05539347CID006857345
Drugchloropropylate

AR ESR2

1.30e-054342ctd:C004663
Drugphantolid

AR ESR2

1.30e-054342ctd:C033117
Drugisobutyl-4-hydroxybenzoate

AR ESR2

1.30e-054342ctd:C045922
Drugethyl bromophos

AR ESR2

1.30e-054342ctd:C041062
DrugPhenylphosphonothioic Acid, 2-Ethyl 2-(4-Nitrophenyl) Ester

AR ESR2

1.30e-054342ctd:D004849
Drugdichlofenthion

AR ESR2

1.30e-054342ctd:C011445
Drugchelerythrine

AKT1 PRKCI PRKCZ TRPC7 PTK2 TRPC6

1.32e-05357346CID000002703
DrugNPC 12626

GRID1 GRID2 AR

1.33e-0531343CID000108099
DrugSurfagon

TRPC7 AR TRPC6

1.61e-0533343CID005484741
Drugdamnacanthal

AKT1 PRKCZ PTK2

1.76e-0534343CID000002948
DrugZeranol

ESR2 TRPC3 TRPC6

1.93e-0535343ctd:D015029
DrugN-methyl-N-(6-methoxy-1-phenyl-1,2,3,4-tetrahydronaphthalen-2-ylmethyl)aminomethylcarboxylic acid

GRID1 GRID2 PRKCI

1.93e-0535343ctd:C520612
Drugsalvianolic acid B

AKT1 TRPC3 TRPC6

1.93e-0535343ctd:C076944
Drugnilutamide

NPC1 AR TRPC6

2.10e-0536343CID000004493
Drugtolclofos-methyl

AR ESR2

2.16e-055342ctd:C426783
Drug2,4',5-trichlorobiphenyl

AR ESR2

2.16e-055342ctd:C015550
Drugprothiophos

AR ESR2

2.16e-055342ctd:C032072
Drugisobutylparaben

AR ESR2

2.16e-055342ctd:C471067
Drug3',5'-dichloro-2-hydroxy-2-methylbut-3-enanilide

AR ESR2

2.16e-055342CID000115209
Drugrifapentine

AR ESR2

2.16e-055342ctd:C018421
Drug3-benzylidene camphor

AR ESR2

2.16e-055342ctd:C511303
DrugLeptophos

AR ESR2

2.16e-055342ctd:D010773
DrugNorethynodrel

AR ESR2

2.16e-055342ctd:D009641
Drugethion

AR ESR2

2.16e-055342ctd:C100038
DrugHU-211

GRID1 GRID2 AKT1 PTK2

2.46e-05114344CID000107778
Drugbis(4-hydroxyphenyl)sulfone

SLC47A1 AKT1 AKT2 AR ESR2 TRPC6

2.55e-05401346ctd:C543008
Drugtrans-3,4,5-trihydroxystilbene

GRID1 GRID2 AKT1 PRKCI AR PTK2 ESR2

2.69e-05608347CID000005056
Drugtautomycin

AKT1 PRKCI AKT2 PRKCZ

2.82e-05118344CID000440646
Drugfadrozole

PRKCI AR ESR2

2.89e-0540343CID000059693
DrugET-18-OCH3

NPC1 AKT1 PRKCI ESR2

3.01e-05120344CID000001392
DrugFactrel

TRPC7 AR ESR2 TRPC3 TRPC6

3.05e-05246345CID000036523
Drug3',5'-dichloro-2-hydroxy-2-methylbut-3-enanilide

AR ESR2

3.23e-056342ctd:C101850
Drug2',3',4',5'-tetrachloro-4-biphenylol

AR ESR2

3.23e-056342ctd:C104006
Drugnilutamide

AKT1 AR

3.23e-056342ctd:C021277
Drugisopropyl 4,4'-dibromobenzilate

AR ESR2

3.23e-056342ctd:C038267
Drugquercetagetin

AKT1 AR

3.23e-056342ctd:C079163
Drugtetralin

AR ESR2

3.23e-056342ctd:C095210
DrugLSOs

NPC1 AKT1 AKT2 ESR2

3.42e-05124344CID000164701
DrugAC1L1K7T

AKT1 PRKCI AKT2 PRKCZ AR PTK2 ESR2

3.44e-05632347CID000005376
DrugSC-9

NPC1 PRKCI PRKCZ

3.60e-0543343CID000124172
DrugHypertensin II

AKT1 PRKCI TRPC7 PTK2 ESR2 TRPC6

3.72e-05429346CID000025476
DrugAC1ND2OB

AKT1 PRKCI PRKCZ AR ESR2

4.34e-05265345CID004568637
Drugtriphenylethylene

PRKCI PRKCZ ESR2

4.42e-0546343CID000006025
Drugmelatonin

GRID1 GRID2 AKT1 PRKCI PRKCZ ESR2

4.44e-05443346CID000000896
Drugdocetaxel

AKT1 ABCA9 AR PTK2

4.50e-05133344ctd:C067311
Drugpendimethalin

AR ESR2

4.52e-057342ctd:C030856
Drug3,5-dichlorobiphenyl

AR ESR2

4.52e-057342ctd:C029904
Drugethyl myristate

AR ESR2

4.52e-057342ctd:C032396
Drugoctyldimethyl-p-aminobenzoic acid

AR ESR2

4.52e-057342CID000042851
Drug(N)-methanocarba-2MeSADP

AKT1 PRKCZ

4.52e-057342ctd:C511689
DrugEpirubicin

AKT1 AR ESR2

4.72e-0547343ctd:D015251
DrugALA-10

TRPC7 TRPC3 TRPC6

4.72e-0547343CID003039342
DrugAC1L1B55

AKT1 PRKCI RPSA PRKCZ AR PTK2

5.09e-05454346CID000001287
DrugHydrocarbons, Chlorinated

AKT1 RPSA AR

5.35e-0549343ctd:D006843
DrugNSC150531

NPC1 PRKCI PRKCZ

5.35e-0549343CID000004475
Drugdi-n-octyl phthalate

AR ESR2

6.03e-058342ctd:C010715
Drug1,3-dihydro-1-(1-((4-(6-phenyl-1H-imidazo(4,5-g)quinoxalin-7-yl)phenyl)methyl)-4-piperidinyl)-2H-benzimidazol-2-one

AKT1 AKT2

6.03e-058342ctd:C532657
Drug1-oleoyl-2-acetoyl-sn-glycerol

TRPC3 TRPC6

6.03e-058342ctd:C520323
DrugCDRI 85-287

AKT1 ESR2

6.03e-058342ctd:C066624
Drugtolclofos-methyl

AR ESR2

6.03e-058342CID000091664
DrugMolPort-016-580-972

AKT1 AKT3 AKT2

6.03e-0551343CID009938589
DrugNSC98537

PRKCI PRKCZ AR PTK2 ESR2 TRPC6

6.39e-05473346CID000005410
DrugN-desmethyl-tamoxifen-hydrochloride

PRKCI PRKCZ ESR2

6.40e-0552343CID000035887
Diseasetype 2 diabetes mellitus (implicated_via_orthology)

AKT1 PRKCI AKT3 AKT2 ZMPSTE24 AR

1.80e-09105336DOID:9352 (implicated_via_orthology)
Diseaseprostate cancer (is_implicated_in)

AKT1 AKT3 AKT2 AR ESR2

1.95e-07117335DOID:10283 (is_implicated_in)
Diseasenicotine dependence (implicated_via_orthology)

TRPC7 TRPC3 TRPC6

2.78e-0712333DOID:0050742 (implicated_via_orthology)
DiseaseBipolar Disorder

GRID1 AKT1 PRKCI AKT2 PRKCZ TRPC7 TRPC3

8.20e-07477337C0005586
Diseasearrhythmogenic right ventricular dysplasia 5 (implicated_via_orthology)

RPSA TMEM43

1.21e-062332DOID:0110074 (implicated_via_orthology)
Diseaseprostate adenocarcinoma (is_implicated_in)

AKT1 AKT3 AKT2

1.43e-0620333DOID:2526 (is_implicated_in)
Diseasemalignant astrocytoma (is_marker_for)

AKT1 AKT3 AKT2

2.22e-0623333DOID:3069 (is_marker_for)
Diseasehypertension (implicated_via_orthology)

AKT1 AR PTK2 ESR2

1.25e-05128334DOID:10763 (implicated_via_orthology)
Diseasehigh grade glioma (implicated_via_orthology)

PRKCI AKT2 PRKCZ

1.64e-0544333DOID:3070 (implicated_via_orthology)
Diseaseleiomyoma (is_implicated_in)

AR PTK2

1.81e-056332DOID:127 (is_implicated_in)
Diseasehypospadias (is_implicated_in)

AR ESR2

3.38e-058332DOID:10892 (is_implicated_in)
DiseaseProstatic Intraepithelial Neoplasias

AR ESR2

6.63e-0511332C0282612
DiseaseColorectal Carcinoma

GRID1 GRID2 AKT1 PRKCZ ABCA9 ESR2

1.14e-04702336C0009402
DiseaseAdenocarcinoma of large intestine

AKT1 AKT2 PRKCZ

1.70e-0496333C1319315
DiseaseMental Depression

GRID1 AKT1 PRKCI AR

1.80e-04254334C0011570
DiseaseAdenocarcinoma of prostate

AKT1 AR

2.28e-0420332C0007112
DiseaseColorectal Neoplasms

GRID1 AKT1 ABCA9 ESR2

2.51e-04277334C0009404
Diseasein situ carcinoma (is_marker_for)

AKT1 ESR2

2.51e-0421332DOID:8719 (is_marker_for)
DiseaseDepressive disorder

GRID1 AKT1 PRKCI AR

2.95e-04289334C0011581
DiseaseNeoplasm of the genitourinary tract

AKT1 AR

3.30e-0424332cv:C0042065
DiseaseHDL cholesterol change measurement

GRID1 ESR2

3.30e-0424332EFO_0007805
DiseaseCerebral Astrocytoma

AR ESR2

3.58e-0425332C0750935
DiseaseIntracranial Astrocytoma

AR ESR2

3.58e-0425332C0750936
DiseasePilocytic Astrocytoma

AR ESR2

3.58e-0425332C0334583
DiseaseAstrocytoma

AR ESR2

3.58e-0425332C0004114
DiseaseJuvenile Pilocytic Astrocytoma

AR ESR2

3.58e-0425332C0280783
DiseaseDiffuse Astrocytoma

AR ESR2

3.58e-0425332C0280785
DiseaseGrade I Astrocytoma

AR ESR2

3.58e-0425332C1704230
DiseaseSubependymal Giant Cell Astrocytoma

AR ESR2

3.58e-0425332C0205768
DiseaseMixed oligoastrocytoma

AR ESR2

3.58e-0425332C0547065
DiseaseChildhood Cerebral Astrocytoma

AR ESR2

3.58e-0425332C0338070
DiseaseGemistocytic astrocytoma

AR ESR2

3.88e-0426332C0334581
DiseaseProtoplasmic astrocytoma

AR ESR2

3.88e-0426332C0334580
DiseaseFibrillary Astrocytoma

AR ESR2

3.88e-0426332C0334582
DiseaseAnaplastic astrocytoma

AR ESR2

4.18e-0427332C0334579
DiseaseHyalinosis, Segmental Glomerular

ZMPSTE24 TRPC6

4.50e-0428332C0086432
DiseaseSubfertility, Female

AR ESR2

4.50e-0428332C0341869
DiseaseSterility, Postpartum

AR ESR2

4.50e-0428332C0038279
Diseaseovarian carcinoma (is_marker_for)

PRKCI PTK2

4.50e-0428332DOID:4001 (is_marker_for)
DiseaseFemale sterility

AR ESR2

4.50e-0428332C0917730
DiseaseFemale infertility

AR ESR2

4.50e-0428332C0021361
DiseaseNeoplasm of uncertain or unknown behavior of ovary

AKT1 AKT2

4.83e-0429332C0496920
DiseaseOvarian Carcinoma

AKT1 AKT2

5.17e-0430332C0029925
Diseasetype 2 diabetes mellitus (biomarker_via_orthology)

AKT1 PRKCZ TRPC6

5.92e-04147333DOID:9352 (biomarker_via_orthology)
DiseaseSpinocerebellar Ataxia Type 2

GRID2 TRPC3

6.65e-0434332C0752121
DiseaseSpinocerebellar Ataxia Type 1

GRID2 TRPC3

6.65e-0434332C0752120
DiseaseSpinocerebellar Ataxia Type 5

GRID2 TRPC3

6.65e-0434332C0752123
DiseaseSpinocerebellar Ataxia Type 7

GRID2 TRPC3

6.65e-0434332C0752125
DiseaseSpinocerebellar Ataxia Type 6 (disorder)

GRID2 TRPC3

6.65e-0434332C0752124
DiseaseAtaxia, Spinocerebellar

GRID2 TRPC3

6.65e-0434332C0087012
DiseaseSpinocerebellar Ataxia Type 4

GRID2 TRPC3

7.05e-0435332C0752122
DiseaseParkinson's disease (implicated_via_orthology)

AKT1 AKT3 AKT2

7.17e-04157333DOID:14330 (implicated_via_orthology)
Diseaseendometrial cancer (is_implicated_in)

AKT2 AR

7.46e-0436332DOID:1380 (is_implicated_in)
Diseasecolon cancer (is_implicated_in)

AKT1 AKT3

7.46e-0436332DOID:219 (is_implicated_in)
DiseaseFocal glomerulosclerosis

ZMPSTE24 TRPC6

7.46e-0436332C0017668
Diseaseductal carcinoma in situ (is_marker_for)

AR PTK2

8.76e-0439332DOID:0060074 (is_marker_for)
Diseasecardioembolic stroke

PTK2 ESR2 TRPC6

9.03e-04170333EFO_1001976
Diseaseinvasive ductal carcinoma (is_marker_for)

PRKCI AR

9.21e-0440332DOID:3008 (is_marker_for)
DiseaseNeoplasm of uncertain or unknown behavior of breast

AKT1 AKT2

9.68e-0441332C0496956
DiseaseBreast adenocarcinoma

AKT1 AKT2

9.68e-0441332C0858252

Protein segments in the cluster

PeptideGeneStartEntry
DWWGLGVVMYEMMCG

AKT1

331

P31749
VDWWGLGVVMYEMMC

AKT2

331

P31751
MMWNWMVSLLATGAA

AACS

336

Q86V21
MTMMGLRESAFWLSW

ABCA9

256

Q8IUA7
WDMQMDGRMAKYWLP

ACMSD

176

Q8TDX5
AVDWWGLGVVMYEMM

AKT3

326

Q9Y243
WDMPWILMLLLTMGQ

LY6G6F

231

Q5SQ64
WWALGVLMFEMMAGR

PRKCI

436

P41743
LESCWMEVLMMGLMW

ESR2

331

Q92731
TTLATRMMMGAWWLF

GRID2

626

O43424
RMMMGAWWLFALIVI

GRID2

631

O43424
MALAMLRDWCRWMGA

PNMA6E

1

A0A0J9YXQ4
GILMDMRWRWMMLVF

KCNJ13

46

O60928
MRWRWMMLVFSASFV

KCNJ13

51

O60928
SWMGLMVFAMGWRSF

AR

741

P10275
MTWSMFAVGWMELKD

PGGHG

536

Q32M88
MWEVMAFGERPYWDM

EPHA10

836

Q5JZY3
VAWTWAGGSVMGMMV

OR10H3

146

O60404
IAMVLVNMFGVMWLW

NPC1

1131

O15118
WMGAWLCLMMQPSHL

BTAF1

606

O14981
NSMAMRIVMGSWWLF

GRID1

626

Q9ULK0
MGMWASLDALWEMPA

ZMPSTE24

1

O75844
VGLMWWMLAREVLRM

RPSA

171

P08865
EMMAQAGSLEWMSLW

RTTN

1336

Q86VV8
WLRWRMNGMIVMLLI

TAS2R42

121

Q7RTR8
MKTWGLRAAGWMAMF

TMEM43

306

Q9BTV4
WRWIFIMVCSEMKGM

SLC9C1

361

Q4G0N8
WMFGVCMWEILMHGV

PTK2

606

Q05397
MAGMALARAWKQMSW

SPTSSA

1

Q969W0
SMLMLCMEWWAYEVG

SLC47A1

266

Q96FL8
MAVTMLQDWCRWMGV

PNMA6A

1

P0CW24
VGWIMSIFWGMDMVI

STUM

111

Q69YW2
WMGDFVTAWMVTDMM

TMEM117

161

Q9H0C3
FSWMEMLIISWVIGM

TRPC6

491

Q9Y210
WRMMNFRQRMGWIGV

TMEM251

31

Q8N6I4
EMLIMVWVLGMMWSE

TRPC3

426

Q13507
FSWTEMLIMKWVLGM

TRPC7

436

Q9HCX4
SVDWWALGVLMFEMM

PRKCZ

431

Q05513