Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionphorbol ester receptor activity

UNC13B UNC13C

1.11e-052672GO:0001565
GeneOntologyMolecularFunctionnon-kinase phorbol ester receptor activity

UNC13B UNC13C

1.11e-052672GO:0001566
GeneOntologyCellularComponentpresynaptic active zone

UNC13B ROCK2 NRG1 UNC13C GRM4

8.97e-05141675GO:0048786
GeneOntologyCellularComponentneuromuscular junction

UNC13B ROCK2 NRG1 UNC13C

4.62e-04112674GO:0031594
GeneOntologyCellularComponentnuclear body

ZC3H14 ADPRS SCRT1 PRPF4 CSNK2B LPXN WT1 ZMYM2 TDG DCAF7

5.71e-049036710GO:0016604
DomainRibosomal_S27e

RPS27 RPS27L

1.19e-052652IPR000592
DomainRibosomal_S27e_Zn-bd_dom

RPS27 RPS27L

1.19e-052652IPR023407
DomainRibosomal_S27e

RPS27 RPS27L

1.19e-052652PF01667
Domain-

RPS27 RPS27L

1.19e-0526522.20.25.100
DomainRibosomal_S27e

RPS27 RPS27L

1.19e-052652PD004466
DomainRIBOSOMAL_S27E

RPS27 RPS27L

1.19e-052652PS01168
DomainUnc-13

UNC13B UNC13C

3.57e-053652IPR027080
DomainC1

UNC13B ROCK2 KMT2C UNC13C

7.71e-0565654SM00109
DomainPE/DAG-bd

UNC13B ROCK2 KMT2C UNC13C

8.19e-0566654IPR002219
DomainMunc13_dom-2

UNC13B UNC13C

1.18e-045652IPR014772
DomainMembr_traf_MHD

UNC13B UNC13C

1.18e-045652PF10540
DomainMHD2

UNC13B UNC13C

1.18e-045652PS51259
DomainMunc13_subgr_dom-2

UNC13B UNC13C

1.18e-045652IPR019558
DomainDUF1041

UNC13B UNC13C

1.18e-045652SM01145
DomainDUF1041

UNC13B UNC13C

2.48e-047652PF06292
DomainMunc13_1

UNC13B UNC13C

2.48e-047652IPR014770
DomainCAPS_dom

UNC13B UNC13C

2.48e-047652IPR010439
DomainMHD1

UNC13B UNC13C

2.48e-047652PS51258
DomainRibosomal_zn-bd

RPS27 RPS27L

4.23e-049652IPR011332
Domain-

ZNF462 SCRT1 ZNF256 WT1 ZNF322 ZNF236 ZIC1 ZNF292 ZNF646

5.45e-046796593.30.160.60
Domainzf-C2H2

ZNF462 SCRT1 ZNF256 WT1 ZNF322 ZNF236 ZIC1 ZNF292 ZNF646

6.31e-04693659PF00096
DomainZnf_C2H2/integrase_DNA-bd

ZNF462 SCRT1 ZNF256 WT1 ZNF322 ZNF236 ZIC1 ZNF292 ZNF646

6.37e-04694659IPR013087
DomainTIL

ZAN MUC5AC

7.70e-0412652PF01826
DomainC8

ZAN MUC5AC

7.70e-0412652PF08742
DomainUnchr_dom_Cys-rich

ZAN MUC5AC

9.08e-0413652IPR014853
DomainC8

ZAN MUC5AC

9.08e-0413652SM00832
DomainEGF

NRG1 ZAN LRP6 LRP8

9.73e-04126654PF00008
DomainC1_1

UNC13B ROCK2 UNC13C

1.03e-0357653PF00130
DomainTIL_dom

ZAN MUC5AC

1.06e-0314652IPR002919
DomainLdl_recept_b

LRP6 LRP8

1.06e-0314652PF00058
DomainLDLRB

LRP6 LRP8

1.06e-0314652PS51120
DomainLY

LRP6 LRP8

1.22e-0315652SM00135
DomainLDLR_classB_rpt

LRP6 LRP8

1.22e-0315652IPR000033
DomainZINC_FINGER_C2H2_2

ZNF462 SCRT1 ZNF256 WT1 ZNF322 ZNF236 ZIC1 ZNF292 ZNF646

1.39e-03775659PS50157
DomainVWD

ZAN MUC5AC

1.39e-0316652SM00216
DomainVWF_type-D

ZAN MUC5AC

1.39e-0316652IPR001846
DomainVWFD

ZAN MUC5AC

1.39e-0316652PS51233
DomainVWD

ZAN MUC5AC

1.39e-0316652PF00094
DomainZINC_FINGER_C2H2_1

ZNF462 SCRT1 ZNF256 WT1 ZNF322 ZNF236 ZIC1 ZNF292 ZNF646

1.41e-03777659PS00028
DomainZF_DAG_PE_1

UNC13B ROCK2 UNC13C

1.44e-0364653PS00479
DomainZF_DAG_PE_2

UNC13B ROCK2 UNC13C

1.44e-0364653PS50081
DomainZnf_C2H2-like

ZNF462 SCRT1 ZNF256 WT1 ZNF322 ZNF236 ZIC1 ZNF292 ZNF646

1.67e-03796659IPR015880
DomainZnf_C2H2

ZNF462 SCRT1 ZNF256 WT1 ZNF322 ZNF236 ZIC1 ZNF292 ZNF646

1.80e-03805659IPR007087
DomainZnF_C2H2

ZNF462 SCRT1 ZNF256 WT1 ZNF322 ZNF236 ZIC1 ZNF292 ZNF646

1.85e-03808659SM00355
DomainVWC_out

ZAN MUC5AC

1.96e-0319652SM00215
DomainDHHC

KMT2C ZDHHC18

3.40e-0325652PS50216
DomainZnf_DHHC_palmitoyltrfase

KMT2C ZDHHC18

3.40e-0325652IPR001594
DomainVWFC_1

ZAN MUC5AC

6.96e-0336652PS01208
Pubmed

Neddylation modification of ribosomal protein RPS27L or RPS27 by MDM2 or NEDP1 regulates cancer cell survival.

RPS27 RPS27L

3.66e-06267232779270
Pubmed

Down-regulation of Wt1 activates Wnt/β-catenin signaling through modulating endocytic route of LRP6 in podocyte dysfunction in vitro.

WT1 LRP6

3.66e-06267226049137
Pubmed

Munc13-independent vesicle priming at mouse photoreceptor ribbon synapses.

UNC13B UNC13C

3.66e-06267222674279
Pubmed

Rock2 regulates Cdc25A through ubiquitin proteasome system in hepatocellular carcinoma cells.

ROCK2 CDC25A

3.66e-06267222705122
Pubmed

Combination of MUC5ac and WT-1 immunohistochemistry is useful in distinguishing pancreatic ductal carcinoma from ovarian serous carcinoma in effusion cytology.

WT1 MUC5AC

3.66e-06267219856421
Pubmed

WT1-dependent sulfatase expression maintains the normal glomerular filtration barrier.

SULF2 WT1

1.10e-05367221719793
Pubmed

The regulatory beta-subunit of protein kinase CK2 accelerates the degradation of CDC25A phosphatase through the checkpoint kinase Chk1.

CSNK2B CDC25A

1.10e-05367217912454
Pubmed

Heterogeneous Presynaptic Distribution of Munc13 Isoforms at Retinal Synapses and Identification of an Unconventional Bipolar Cell Type with Dual Expression of Munc13 Isoforms: A Study Using Munc13-EXFP Knock-in Mice.

UNC13B UNC13C

1.10e-05367233105896
Pubmed

The Munc13 proteins differentially regulate readily releasable pool dynamics and calcium-dependent recovery at a central synapse.

UNC13B UNC13C

1.10e-05367223658173
Pubmed

Subfunctionalized expression drives evolutionary retention of ribosomal protein paralogs Rps27 and Rps27l in vertebrates.

RPS27 RPS27L

1.10e-05367237306301
Pubmed

Regulation of neuregulin 1beta1-induced MUC5AC and MUC5B expression in human airway epithelium.

NRG1 MUC5AC

1.10e-05367219556605
Pubmed

Nonconserved Ca(2+)/calmodulin binding sites in Munc13s differentially control synaptic short-term plasticity.

UNC13B UNC13C

1.10e-05367222966208
Pubmed

Aberrant morphology and residual transmitter release at the Munc13-deficient mouse neuromuscular synapse.

UNC13B UNC13C

1.10e-05367215988013
Pubmed

Munc13-2-/- baseline secretion defect reveals source of oligomeric mucins in mouse airways.

UNC13B MUC5AC

2.19e-05467218258655
Pubmed

Receptor-type protein tyrosine phosphatase zeta as a component of the signaling receptor complex for midkine-dependent survival of embryonic neurons.

LRP6 LRP8

2.19e-05467212573468
Pubmed

Ribosomal protein S27-like and S27 interplay with p53-MDM2 axis as a target, a substrate and a regulator.

RPS27 RPS27L

2.19e-05467221170087
Pubmed

Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.

ZNF462 WT1 ZMYM2 ZNF322 ZNF236 DCUN1D4 ZNF292 VDR ZNF646

2.42e-0580867920412781
Pubmed

DNA damage-dependent interaction of the nuclear matrix protein C1D with Translin-associated factor X (TRAX).

PRKDC GRM4

3.64e-05567211801738
Pubmed

An active vesicle priming machinery suppresses axon regeneration upon adult CNS injury.

UNC13B UNC13C

3.64e-05567234706221
Pubmed

Identification of a Munc13-sensitive step in chromaffin cell large dense-core vesicle exocytosis.

UNC13B UNC13C

3.64e-05567226575293
Pubmed

Whn and mHa3 are components of the genetic hierarchy controlling hair follicle differentiation.

KRT31 KRT33B

5.46e-05667210559501
Pubmed

Kinetic properties of p53 phosphorylation by the human vaccinia-related kinase 1.

CSNK2B PRKDC

5.46e-05667211883897
Pubmed

The human vaccinia-related kinase 1 (VRK1) phosphorylates threonine-18 within the mdm-2 binding site of the p53 tumour suppressor protein.

CSNK2B PRKDC

5.46e-05667210951572
Pubmed

MKRN2 Physically Interacts with GLE1 to Regulate mRNA Export and Zebrafish Retinal Development.

UNC13B ZC3H14 CSNK2B ZMYM2 GDF11 LRP8

6.71e-0535867632460013
Pubmed

Munc13 supports fusogenicity of non-docked vesicles at synapses with disrupted active zones.

UNC13B UNC13C

7.63e-05767236398873
Pubmed

DKK2 imparts tumor immunity evasion through β-catenin-independent suppression of cytotoxic immune-cell activation.

LRP6 PRKDC

7.63e-05767229431745
Pubmed

Unconventional molecular regulation of synaptic vesicle replenishment in cochlear inner hair cells.

UNC13B UNC13C

1.02e-04867225609709
Pubmed

LXR/ApoE Activation Restricts Innate Immune Suppression in Cancer.

PRKDC LRP8

1.02e-04867229336888
Pubmed

Characterization of a 190-kilobase pair domain of human type I hair keratin genes.

KRT31 KRT33B

1.30e-0496729756910
Pubmed

T:G mismatch-specific thymine-DNA glycosylase potentiates transcription of estrogen-regulated genes through direct interaction with estrogen receptor alpha.

TDG VDR

1.30e-04967212874288
Pubmed

Stress-induced activation of protein kinase CK2 by direct interaction with p38 mitogen-activated protein kinase.

CSNK2B PRKDC

1.30e-04967210747897
Pubmed

Human hair keratins.

KRT31 KRT33B

1.30e-0496727686952
Pubmed

Ribosomal protein S27-like is a physiological regulator of p53 that suppresses genomic instability and tumorigenesis.

RPS27 RPS27L

1.30e-04967225144937
Pubmed

Upregulation of RIN3 induces endosomal dysfunction in Alzheimer's disease.

RAB6D ADPRS CSNK2B RPS27 RPS27L DCAF7

1.56e-0441867632552912
Pubmed

The catalog of human hair keratins. I. Expression of the nine type I members in the hair follicle.

KRT31 KRT33B

1.63e-041067210391933
Pubmed

Regulation of metanephric kidney development by growth/differentiation factor 11.

WT1 GDF11

1.63e-041067212729564
Pubmed

A direct physical interaction between Nanog and Sox2 regulates embryonic stem cell self-renewal.

ZNF462 KMT2C ZMYM2 DCAF7

1.86e-0414667423892456
Pubmed

Molecular and functional architecture of striatal dopamine release sites.

UNC13B UNC13C

1.99e-041167234767769
Pubmed

UV-radiation induces dose-dependent regulation of p53 response and modulates p53-HDM2 interaction in human fibroblasts.

CSNK2B PRKDC

1.99e-041167211709713
Pubmed

An Oct4-centered protein interaction network in embryonic stem cells.

ZNF462 KMT2C ZMYM2 PRKDC

3.11e-0416767420362541
Pubmed

UHRF2 commissions the completion of DNA demethylation through allosteric activation by 5hmC and K33-linked ubiquitination of XRCC1.

TDG PRKDC

3.28e-041467234111398
Pubmed

Rubella vaccine-induced cellular immunity: evidence of associations with polymorphisms in the Toll-like, vitamin A and D receptors, and innate immune response genes.

TRIM5 VDR

3.28e-041467219902255
Pubmed

Stage-specific association of apolipoprotein A-I and E in developing mouse retina.

LRP6 LRP8

3.28e-041467217389516
Pubmed

USP7 Cooperates with NOTCH1 to Drive the Oncogenic Transcriptional Program in T-Cell Leukemia.

RPS27 RPS27L DCAF7

3.86e-047367330224337
Pubmed

A High-Density Map for Navigating the Human Polycomb Complexome.

ZNF462 KMT2C CSNK2B ZMYM2 ZNF292 DCAF7

3.86e-0449567627705803
Pubmed

Activity-dependent neuroprotective protein recruits HP1 and CHD4 to control lineage-specifying genes.

ZNF462 ZMYM2 ZNF292

4.02e-047467329795351
Pubmed

A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.

ZNF462 KMT2C LPXN WT1 FOXN3 ZNF292 VDR

4.28e-0470967722988430
Pubmed

Myocardial-specific R-spondin3 drives proliferation of the coronary stems primarily through the Leucine Rich Repeat G Protein coupled receptor LGR4.

WT1 TRIM5

4.31e-041667229859889
Pubmed

Tagging genes with cassette-exchange sites.

ZNF462 KMT2C STMN2 FOXN3 ZNF292

4.77e-0433567515741177
Pubmed

Genetic Targeting of Organ-Specific Blood Vessels.

NRG1 WT1

4.88e-041767229764841
Pubmed

NRF1 association with AUTS2-Polycomb mediates specific gene activation in the brain.

CSNK2B DCAF7

4.88e-041767234637754
Pubmed

The ECM protein nephronectin promotes kidney development via integrin alpha8beta1-mediated stimulation of Gdnf expression.

WT1 GDF11

5.48e-041867217537792
Pubmed

Identification of tooth-specific downstream targets of Runx2.

ROCK2 CSNK2B

5.48e-041867211722849
Pubmed

Independent functions and mechanisms for homeobox gene Barx1 in patterning mouse stomach and spleen.

WT1 MUC5AC

6.12e-041967217855428
Pubmed

Hand2 loss-of-function in Hand1-expressing cells reveals distinct roles in epicardial and coronary vessel development.

NRG1 WT1

6.79e-042067221350214
Pubmed

NRG1 signalling regulates the establishment of Sertoli cell stock in the mouse testis.

NRG1 WT1

7.50e-042167230040984
Pubmed

MESD is essential for apical localization of megalin/LRP2 in the visceral endoderm.

LRP6 LRP8

7.50e-042167221337463
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

UNC13B ACAD8 CSNK2B HECTD4 ZMYM2 PRKDC TRIM5 RECK ZNF292

7.77e-04128567935914814
Pubmed

Lineage dynamics of murine pancreatic development at single-cell resolution.

WT1 STMN2

8.24e-042267230254276
Pubmed

Specification of SUMO1- and SUMO2-interacting motifs.

ZMYM2 TDG

8.24e-042267216524884
Pubmed

Requirement for LIM homeobox gene Isl1 in motor neuron generation reveals a motor neuron-dependent step in interneuron differentiation.

NRG1 STMN2

8.24e-04226728565076
Pubmed

m6A epitranscriptomic modification regulates neural progenitor-to-glial cell transition in the retina.

SULF2 ZNF292

8.24e-042267236459087
Pubmed

TRIM33 drives prostate tumor growth by stabilizing androgen receptor from Skp2-mediated degradation.

ZNF462 KMT2C PRKDC DCAF7

8.74e-0422067435785414
Pubmed

Wnt9b-dependent FGF signaling is crucial for outgrowth of the nasal and maxillary processes during upper jaw and lip development.

ROCK2 LRP6

9.01e-042367222461561
Pubmed

Fras1, a basement membrane-associated protein mutated in Fraser syndrome, mediates both the initiation of the mammalian kidney and the integrity of renal glomeruli.

WT1 GDF11

9.01e-042367218787044
Pubmed

Essential pro-Bmp roles of crossveinless 2 in mouse organogenesis.

WT1 ZIC1

1.07e-032567217035289
Pubmed

Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.

KMT2C DNAH2 ZNF322 ZNF292

1.08e-0323367437704626
Pubmed

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.

ZNF462 SULF2 PRPF4 HECTD4 ZMYM2 PRKDC RPS27L ZNF292

1.10e-03108267838697112
Pubmed

Direct binding of CoREST1 to SUMO-2/3 contributes to gene-specific repression by the LSD1/CoREST1/HDAC complex.

ZMYM2 TDG PRKDC

1.14e-0310667319394292
Pubmed

Rewiring the retinal ganglion cell gene regulatory network: Neurod1 promotes retinal ganglion cell fate in the absence of Math5.

STMN2 GDF11

1.15e-032667218787067
Pubmed

Aberrant centrosome biogenesis disrupts nephron and collecting duct progenitor growth and fate resulting in fibrocystic kidney disease.

ROCK2 WT1

1.15e-032667237982452
Pubmed

Redundant functions of RIM1alpha and RIM2alpha in Ca(2+)-triggered neurotransmitter release.

UNC13B UNC13C

1.15e-032667217124501
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

ZC3H14 KMT2C PRPF4 WT1 ZMYM2 PRKDC ZNF292 DCAF7

1.24e-03110367834189442
Pubmed

Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System.

ZNF462 NRG1 FOXN3 LRP8

1.42e-0325167429031500
Pubmed

SETD1A Methyltransferase Is Physically and Functionally Linked to the DNA Damage Repair Protein RAD18.

KMT2C PRPF4 CSNK2B PRKDC

1.42e-0325167431076518
Pubmed

An atlas of combinatorial transcriptional regulation in mouse and man.

WT1 ZMYM2 ZNF236 TRIM5 ZIC1 ZNF292 VDR

1.48e-0387767720211142
Pubmed

Viral immune modulators perturb the human molecular network by common and unique strategies.

CSNK2B RPS27 RPS27L

1.48e-0311667322810585
Pubmed

CRL4AMBRA1 is a master regulator of D-type cyclins.

CDC25A DCAF7

1.54e-033067233854235
Pubmed

The synaptic vesicle cycle.

UNC13B UNC13C

1.64e-033167215217342
Cytoband2q21.1

RAB6D MYO7B RAB6C

8.65e-05586732q21.1
Cytoband14q31.3

ZC3H14 FOXN3

1.62e-041367214q31.3
CytobandEnsembl 112 genes in cytogenetic band chr11q12

TRIM51 LPXN OR10W1 OR5M8

1.65e-03345674chr11q12
Cytoband11q12.1

LPXN OR10W1 OR5M8

1.72e-0316167311q12.1
Cytoband12q13.2

GDF11 TESPA1

2.96e-035567212q13.2
GeneFamilyUNC13 homologs

UNC13B UNC13C

4.85e-054522836
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF462 SCRT1 ZNF256 WT1 ZNF322 ZNF236 ZIC1 ZNF292 ZNF646

1.86e-0471852928
GeneFamilyLow density lipoprotein receptors

LRP6 LRP8

6.20e-0413522634
GeneFamilyKeratins, type I

KRT31 KRT33B

2.92e-0328522608
GeneFamilyS ribosomal proteins

RPS27 RPS27L

4.29e-0334522728
CoexpressionBROWNE_HCMV_INFECTION_8HR_DN

LPXN ZIC1 LRP8 VDR

6.56e-0648664M7846
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCRT1 KRT33B STMN2 UNC13C GRM4 ZIC1

4.09e-071896763d838da870623a6a278ddc8e6cedca85d9877e50
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Neuronal-interneuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCRT1 STMN2 UNC13C GRM4 ZIC1

8.98e-06186675a1ab273b01971d6a892912560d387685dd657179
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCRT1 STMN2 UNC13C GRM4 ZIC1

9.21e-06187675ef3c85c01bc3da408ae288b6e3096ad888a12e63
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACER2 NRG1 FMO1 WT1 STMN2

1.05e-0519267524d28e28a5c54ca7770f7e5ad7f4d00039e0aaf9
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-IPC/newborn-38|World / Primary Cells by Cluster

ZNF462 HECTD4 FOXN3 LRP8 ZNF292

1.16e-0519667538da0751941adca650fe9b383d9f343153978eb5
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-IPC/newborn|World / Primary Cells by Cluster

ZNF462 HECTD4 FOXN3 LRP8 ZNF292

1.16e-05196675721650a08d260faf530dbd52d4e9275d27f3bac2
ToppCellPosterior_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb-Inhibitory_Neuron.Gad1Gad2.Pvalb-Nefm_(Neuron.Gad1Gad2.Pvalb-Nefm)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

KRT31 WT1 MYRFL

4.58e-0546673aa8a399b8e81a6c6fdd4191c97ebe0f75f096098
ToppCellPosterior_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb-Inhibitory_Neuron.Gad1Gad2.Pvalb-Nefm_(Neuron.Gad1Gad2.Pvalb-Nefm)-|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

KRT31 WT1 MYRFL

4.58e-0546673aa551a40a23454011eda66380571ea899defa6df
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c06-TNF|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

DCUN1D4 TRIM5 LRP8 MYBPC3

5.91e-05140674276b3fa924176426efb31112ed4d355407f0b218
ToppCellfacs-Heart-RA-24m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACER2 FMO1 WT1 STMN2

6.96e-05146674d903e091a917d3f5dcf82107e636520f75e47403
ToppCellfacs-Heart-RA-24m-Endothelial-endothelial_cell_of_coronary_artery|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACER2 FMO1 WT1 STMN2

6.96e-051466749c9218e5257253597f2fd74fbd589b962d3078a3
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-NP|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ACER2 UNC13B UNC13C GRM4

7.73e-051506742ba55e51877e2e749cccdae7df5d885dc55b2587
ToppCellE16.5-Immune-Immune_Myeloid-Monocytic-Macrophage-AM|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PLA1A LPXN LRP8 VDR

9.68e-051596740c2437da5443fc3aff66f8ef311f02aa434a1fb0
ToppCellClub-club-16|World / Class top

SULF2 STMN2 ZNF236 OAZ3

1.12e-04165674684f3c4872bd630d3f744f15d57dccfd34e96160
ToppCelldroplet-Limb_Muscle-nan-3m-Myeloid-chondrocyte-like|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF462 SHLD2 PRKDC DCUN1D4

1.14e-0416667435db3022c33d6f8bb6587d9eec89a7cccb70271a
ToppCelldroplet-Lung-30m-Hematologic-myeloid-plasmacytoid_dendritic_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ABHD17B MUC5AC TESPA1 LRP8

1.34e-041736744f0c065e876197ad8cae7856669f09e37ecafa3f
ToppCellwk_15-18-Hematologic-Myeloid-Eosinophil|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

ZAN CDC25A TESPA1 MYBPC3

1.34e-04173674a85cead231e03945fabbc7762540ad21fe4299df
ToppCelldroplet-Lung-30m-Hematologic-myeloid-plasmacytoid_dendritic_cell-plasmacytoid_dendritic|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ABHD17B MUC5AC TESPA1 LRP8

1.34e-041736749bbea566964281f47bf75d665b7d69ba8326e207
ToppCellfacs-Lung-Endomucin-24m-Endothelial|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACER2 FMO1 DNAH2 STMN2

1.37e-04174674ea27868d0373843a5137569ac3f9e3f8c92c7dcc
ToppCellfacs-Lung-Endomucin-24m|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACER2 FMO1 DNAH2 STMN2

1.37e-0417467460a426bfe5625999f031776ab34f7bc0d2b331be
ToppCellfacs-Lung-Endomucin-24m-Endothelial-endothelial_cell_of_lung|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACER2 FMO1 DNAH2 STMN2

1.40e-04175674eedb33e3e350169d1d37f2ac9939dcf704e7b696
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Neuronal-interneuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STMN2 UNC13C GRM4 ZIC1

1.40e-0417567465571d775d26a40e979dbf290a8e4320c0d9fb3f
ToppCellfacs-Lung-Endomucin-24m-Endothelial-Capillary_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACER2 FMO1 DNAH2 STMN2

1.40e-041756741c7725f917f3d6b9e0a31ede9524690f408a5ea1
ToppCellHippocampus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a6-Excitatory_Neuron.Slc17a6.Nts_(Neuron.Slc17a6.Nts)-|Hippocampus / BrainAtlas - Mouse McCarroll V32

ZAN KCNH4 MYBPC3

1.41e-0467673bc06a697f47b60c43e238f8c6803a1b061f22550
ToppCellHippocampus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a6-Excitatory_Neuron.Slc17a6.Nts_(Neuron.Slc17a6.Nts)|Hippocampus / BrainAtlas - Mouse McCarroll V32

ZAN KCNH4 MYBPC3

1.41e-046767350acd69659f6d827868dc48bfb00af8634a8b4c7
ToppCelldroplet-Lung-nan-3m-Myeloid-Proliferating_Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SULF2 CDC25A KCNH4 VDR

1.49e-04178674de6cd81e6d58e7687386df163471bf1901b9c0aa
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACER2 FMO1 WT1 STMN2

1.53e-04179674fca111789d7354de7ae4cd38253aa0685c0cb2d2
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACER2 FMO1 WT1 STMN2

1.53e-04179674c3e53a3b8e59f7245d737386a1dd0f9d7aa5fb61
ToppCelldroplet-Lung-nan|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACER2 FMO1 STMN2 RPS27

1.53e-04179674006f2b6887b0f1f26e58bb11c919468b62bf4d62
ToppCelldroplet-Liver-LIVER-30m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WT1 STMN2 UNC13C ZIC1

1.56e-041806743d95232b5785c705f41e01e3ffe0fa8dce1ff0a7
ToppCellfacs-Marrow-T_cells-18m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FMO1 LPXN STMN2 RPS27

1.56e-04180674243622eee35d38748e945677ff115616e763e3b4
ToppCellfacs-Heart-RA-24m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACER2 FMO1 WT1 STMN2

1.56e-04180674174c643e046646e3b305dd7e5b120d2c9a46690f
ToppCelldroplet-Liver-LIVER-30m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WT1 STMN2 UNC13C ZIC1

1.56e-0418067447e345359064dc8ceec982b062e47802e728b43f
ToppCellfacs-Marrow-T_cells-18m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FMO1 LPXN STMN2 RPS27

1.56e-041806743a8d9a71efe113d1df3933902a625c0a56812074
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

UNC13B NRG1 GRM4 LRP8

1.59e-0418167408f44323bf71b6004a921bbc969c954c75feeb66
ToppCellCOVID-19-kidney-PCT-S1|kidney / Disease (COVID-19 only), tissue and cell type

ZNF462 NRG1 FMO1 MYO7B

1.70e-0418467451ed1ebfdef45149541917c66cbacad87072e51f
ToppCellfacs-Brain_Non-Myeloid-Cerebellum|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRG1 STMN2 UNC13C ZIC1

1.73e-04185674c083a4974590b9ed3ecafedd3e9cdebc5047fe39
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L4-5_RORB_RPL31P31|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NRG1 SULF2 STMN2 UNC13C

1.73e-04185674a1b2525da018abe458908cab7268bd403ee98d92
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRG1 STMN2 UNC13C ZIC1

1.81e-041876747b2cd0c618ed081223343f3bec2244c8723c9a31
ToppCellE18.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SHLD2 ZDHHC18 FMO1 STMN2

1.81e-041876743699d5e71d779da922920aa3160895db187bf81b
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-interneuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STMN2 UNC13C GRM4 ZIC1

1.81e-041876741b2fdbfb1ce3f19795dfc4b1da5a94f4b057ec41
ToppCellE18.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SHLD2 ZDHHC18 FMO1 STMN2

1.81e-04187674033ba52c0c2f9978784947098fa697368ae44834
ToppCellfacs-Lung-3m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ACER2 FMO1 STMN2 UNC13C

1.81e-041876747170694a1b86fe8d84d96c880ffe57af09bdc026
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Endothelial-endothelial_cell_of_coronary_artery|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACER2 FMO1 WT1 STMN2

1.84e-041886748a87daf2851d9404df7c36f279db599574b47c69
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACER2 FMO1 WT1 STMN2

1.84e-041886740f426cca2ad7671fed9c6d2aa09f6a8627a518cd
ToppCellfacs-MAT-Fat-3m|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FMO1 SULF2 LRP6 RPS27

1.84e-041886747da9750255efbc5cf9aed7e3105a337fac63b9f0
ToppCelldroplet-Lung-nan-18m-Endothelial-Artery_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACER2 UNC13B FMO1 STMN2

1.84e-04188674405efea75233ecf70f7d19b630230798d817b7f2
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACER2 FMO1 WT1 STMN2

1.84e-04188674aec7485f1a9412bd3a62b70c801cb7f8dcca232d
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCRT1 STMN2 UNC13C ZIC1

1.88e-04189674f57200c93d39c9bce1adba0a6a1c178c028dd86b
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACER2 FMO1 WT1 STMN2

1.92e-04190674f98e2d45fab7d9e16629d7f13cc2ccfb939ef4dd
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Endothelial-endothelial_cell_of_coronary_artery|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACER2 FMO1 WT1 STMN2

1.96e-041916745020fe6c3452e7fab57847f5043d28ebbc5aa381
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Layer_VI_Occipital|World / Primary Cells by Cluster

ZNF462 KRT31 TDG RPS27

1.96e-04191674467d6164aee7745d610cab512616dc7b69d2d8bd
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Layer_VI_Occipital-15|World / Primary Cells by Cluster

ZNF462 KRT31 TDG RPS27

1.96e-04191674190fadf6d7c5ba34d83ad6e5fa008451660db9cf
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCRT1 STMN2 UNC13C ZIC1

2.04e-041936745fb7808dd971c1cc64c2bd4f8f1de646fb2d77f4
Diseasedementia (is_implicated_in)

NRG1 LRP8

3.01e-0412642DOID:1307 (is_implicated_in)
DiseaseIntellectual Disability

ZNF462 ZC3H14 KMT2C ADPRS ZMYM2 ZNF292

4.17e-04447646C3714756
Diseasesquamous cell carcinoma (is_implicated_in)

KMT2C VDR

6.93e-0418642DOID:1749 (is_implicated_in)
DiseaseCraniosynostosis

ZNF462 ZIC1

8.58e-0420642C0010278
DiseaseEpilepsy, Benign Psychomotor, Childhood

GRM4 VDR

1.14e-0323642C0393672
DiseaseEpilepsy, Lateral Temporal

GRM4 VDR

1.14e-0323642C0393682
DiseaseUncinate Epilepsy

GRM4 VDR

1.14e-0323642C0014558
DiseaseEpilepsy, Temporal Lobe

GRM4 VDR

1.14e-0323642C0014556
Diseasetuberculosis (is_implicated_in)

NRG1 VDR

1.69e-0328642DOID:399 (is_implicated_in)

Protein segments in the cluster

PeptideGeneStartEntry
YRCLSFQPECSMKLT

VDR

401

P11473
CYVMPSSSARCAQFP

TDG

266

Q13569
CSSSDCFNKVMPPRK

DCUN1D4

51

Q92564
CPPLCTMEKFASYCL

ACAD8

146

Q9UKU7
PPICMCLFRQYATCF

ACER2

46

Q5QJU3
TCKTCPYDMRPTENR

GRM4

556

Q14833
CRNTFDHPYPTTKLM

DCAF7

61

P61962
ASRKCCISYSFLPKP

DEFB132

51

Q7Z7B7
RKMDPSCTIGFYCRN

ATG4C

376

Q96DT6
CSCYSPMSSSTLPQK

RAB6C

206

Q9H0N0
CSCYSPMSSSTLPQK

RAB6D

206

Q53S08
PMRNPTDSLYCCDRA

RECK

206

O95980
CFMVKDLSNPSRYLC

NRG1

196

Q02297
CAFMYLCPSSSYNPK

OR10W1

246

Q8NGF6
MPCKRCRPSVYSLSY

OAZ3

1

Q9UMX2
FDCSMCRPYMPASNV

KMT2C

1131

Q8NEZ4
MPYNFCLPSLSCRTS

KRT31

1

Q15323
CYFSDPDCSMRPTLI

FBXO39

316

Q8N4B4
YCCPIRGMKEVSSSP

MYRFL

711

Q96LU7
MQKTCSCRFLYGPET

KCNH4

61

Q9UQ05
LCLMSPVKPFYQCAC

LRP6

296

O75581
PYCRKDFLAMFSPKC

LPXN

256

O60711
MCPFTCPADKVYQPC

MUC5AC

5211

P98088
DSPNKPCCRFTYLTM

HECTD4

3781

Q9Y4D8
DPCKMRNSSYCNLSI

GFRAL

56

Q6UXV0
PNCKPPYSFSCLIFM

FOXN3

111

O00409
NSCKEMSCYSDFPFP

FMO1

61

Q01740
CCTPTKMSPINMLYF

GDF11

371

O95390
SVPTAIYCFLRCMEP

ADPRS

276

Q9NX46
YCPKCMDVYTPKSSR

CSNK2B

136

P67870
YQLMSEPQFSRCSKP

DNAH2

3961

Q9P225
SSHSPKYTCACPDTM

LRP8

711

Q14114
KEFFMKCQSYCEPPS

CDC25A

471

P30304
KCQSYCEPPSYRPMH

CDC25A

476

P30304
MPVKCCFYRSPTAET

RGS21

1

Q2M5E4
ARRCPTCGKVYVSMP

SCRT1

221

Q9BWW7
CKRPLPCMTYQPKAT

FER1L5

631

A0AVI2
DRPISYCHFSPNSKM

PRPF4

231

O43172
QSPNSYFMDVKCPGC

RPS27L

26

Q71UM5
NRIYKQCFSCLPFTM

SHLD2

711

Q86V20
CNPLLYGSRMSKSVC

OR5M8

126

Q8NGP6
CMFVRCSPNAKYTLL

ABHD17B

81

Q5VST6
LENSCPLMAFPCASY

PLA1A

271

Q53H76
YLNPRKCGVPMTLCS

TRIM5

476

Q9C035
SCLSSKYMCPGVPAV

UNC13C

1426

Q8NB66
RALTCPICMNYFLDP

TRIM51

11

Q9BSJ1
TRPYMCSECGKSFSQ

ZNF256

376

Q9Y2P7
RFVTQYPCMIKGCTS

ZNF292

2381

O60281
PYKCLECMRSFTRSA

ZNF322

266

Q6U7Q0
EYQCSLCPRKYPNLM

ZNF646

491

O15015
YSCPTCPKTYSNRMA

ZNF646

1326

O15015
ETSEKRPFMCAYPGC

WT1

316

P19544
TLYHFPTNCEACMKP

ROCK2

1266

O75116
ACLSSKYMCPGVPAV

UNC13B

806

O14795
FPQYSPKMQLVCCRA

PRKDC

446

P78527
TANPSRCPVKMFECY

ZMYM2

1296

Q9UBW7
RCPVKMFECYLSKSP

ZMYM2

1301

Q9UBW7
PYLCKMCDKSYTHPS

ZIC1

361

Q15915
KCPAPCQMTYIKSPA

XP32

111

Q5T750
PTQAAPLHPYKCTMC

ZNF462

591

Q96JM2
PLHPYKCTMCNYSTT

ZNF462

596

Q96JM2
NDLRPYMCPYCQKTF

ZNF236

736

Q9UL36
SMLSLICSCFYPEPR

STMN2

16

Q93045
AISKMCLYTCPRDRP

TESPA1

286

A2RU30
PSSSQLCRYFPACKK

ZC3H14

676

Q6PJT7
QSPNSYFMDVKCPGC

RPS27

26

P42677
PMCCPSRSSILTGKY

SULF2

86

Q8IWU5
LKYCFTCKMFRPPRT

ZDHHC18

191

Q9NUE0
FCPMACPPNSKYSLC

ZAN

1421

Q9Y493
MPYNFCLPSLSCRTS

KRT33B

1

Q14525
LCLGCFPPSERFMKY

MYO7B

1136

Q6PIF6
YTAMLCCAVRGSPKP

MYBPC3

1196

Q14896