Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyCellularComponent	cornified envelope	KRT75 PKP3 HRNR FLG2	2.23e-05	69	50	4	GO:0001533
GeneOntologyCellularComponent	keratohyalin granule	HRNR FLG2	5.58e-05	5	50	2	GO:0036457
Domain	RCC1	MYCBP2 HERC4	1.29e-03	20	50	2	PF00415
Domain	RCC1_3	MYCBP2 HERC4	1.43e-03	21	50	2	PS50012
Domain	RCC1_1	MYCBP2 HERC4	1.43e-03	21	50	2	PS00625
Domain	RCC1_2	MYCBP2 HERC4	1.43e-03	21	50	2	PS00626
Domain	Reg_chr_condens	MYCBP2 HERC4	1.57e-03	22	50	2	IPR000408
Domain	-	MYCBP2 HERC4	1.57e-03	22	50	2	2.130.10.30
Domain	RCC1/BLIP-II	MYCBP2 HERC4	1.71e-03	23	50	2	IPR009091
Domain	S100_CABP	HRNR FLG2	2.36e-03	27	50	2	PS00303
Domain	S_100	HRNR FLG2	2.36e-03	27	50	2	PF01023
Domain	DnaJ_domain_CS	DNAJB1 DNAJB14	2.36e-03	27	50	2	IPR018253
Domain	S100_Ca-bd_sub	HRNR FLG2	2.54e-03	28	50	2	IPR013787
Domain	S100/CaBP-9k_CS	HRNR FLG2	2.54e-03	28	50	2	IPR001751
Domain	S_100	HRNR FLG2	2.54e-03	28	50	2	SM01394
Domain	-	FOXE1 DVL3 RFX7 FOXK1	2.73e-03	218	50	4	1.10.10.10
Domain	WHTH_DNA-bd_dom	FOXE1 DVL3 RFX7 FOXK1	3.97e-03	242	50	4	IPR011991
Domain	TF_fork_head_CS_2	FOXE1 FOXK1	6.74e-03	46	50	2	IPR030456
Domain	TF_fork_head_CS_1	FOXE1 FOXK1	7.03e-03	47	50	2	IPR018122
Domain	DnaJ	DNAJB1 DNAJB14	7.32e-03	48	50	2	PF00226
Domain	FORK_HEAD_3	FOXE1 FOXK1	7.62e-03	49	50	2	PS50039
Domain	FH	FOXE1 FOXK1	7.62e-03	49	50	2	SM00339
Domain	FORK_HEAD_1	FOXE1 FOXK1	7.62e-03	49	50	2	PS00657
Domain	FORK_HEAD_2	FOXE1 FOXK1	7.62e-03	49	50	2	PS00658
Domain	Forkhead	FOXE1 FOXK1	7.62e-03	49	50	2	PF00250
Domain	Fork_head_dom	FOXE1 FOXK1	7.62e-03	49	50	2	IPR001766
Domain	DnaJ	DNAJB1 DNAJB14	7.62e-03	49	50	2	SM00271
Domain	DNAJ_1	DNAJB1 DNAJB14	7.62e-03	49	50	2	PS00636
Domain	DNAJ_2	DNAJB1 DNAJB14	7.62e-03	49	50	2	PS50076
Domain	-	DNAJB1 DNAJB14	7.62e-03	49	50	2	1.10.287.110
Domain	DnaJ_domain	DNAJB1 DNAJB14	8.24e-03	51	50	2	IPR001623
Domain	zf-RING_2	MYCBP2 PJA1	8.55e-03	52	50	2	PF13639
Pubmed	Interaction network of human early embryonic transcription factors.	PRR12 TCF20 ZNF608 GPS2 PITX1 HRNR FLG2 RFX7 FOXK1	1.71e-09	351	50	9	38297188
Pubmed	TRIM30 modulates Interleukin-22-regulated papillary thyroid Cancer cell migration and invasion by targeting Sox17 for K48-linked Polyubiquitination.	ILF3 HRNR FLG2	1.55e-06	16	50	3	31823782
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	PRR12 OTX1 ILF3 DDX17 TCF20 PKP3 FOSL2 GPS2 PITX1 RFX7 FOXK1	1.78e-06	1294	50	11	30804502
Pubmed	A keratin scaffold regulates epidermal barrier formation, mitochondrial lipid composition, and activity.	KRT75 PKP3 HRNR FLG2	1.98e-06	62	50	4	26644517
Pubmed	Plakophilin 3 and Par3 facilitate desmosomes' association with the apical junctional complex.	PKP3 PARD3	2.03e-06	2	50	2	34260281
Pubmed	Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.	PRR12 TCF20 ZNF608 FOSL2 GPS2 FOXK1	2.37e-06	268	50	6	33640491
Pubmed	Proteomic Analysis of the EWS-Fli-1 Interactome Reveals the Role of the Lysosome in EWS-Fli-1 Turnover.	PRR12 DNAJB1 OTX1 DDX17 TCF20 PITX1 HRNR	2.46e-06	425	50	7	24999758
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	PRR12 DNAJB1 ILF3 DDX17 TCF20 MYCBP2 FOSL2 GPS2 PITX1 FOXK1	3.20e-06	1103	50	10	34189442
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	DNAJB1 TCF20 MAP2 MYCBP2 FAM98A DPP8 RFX7 PARD3 FOXK1	3.38e-06	861	50	9	36931259
Pubmed	New roles for the de-ubiquitylating enzyme OTUD4 in an RNA-protein network and RNA granules.	DNAJB1 ILF3 DDX17 TENT4A MYCBP2 FAM98A DNAJB14	4.25e-06	462	50	7	31138677
Pubmed	Defects of filaggrin-like proteins in both lesional and nonlesional atopic skin.	HRNR FLG2	6.07e-06	3	50	2	23403047
Pubmed	An inducible CRISPR/Cas9 screen identifies DTX2 as a transcriptional regulator of human telomerase.	PRR12 TCF20 PKP3 GPS2 RFX7	6.16e-06	180	50	5	35198878
Pubmed	Identification of the SOX2 Interactome by BioID Reveals EP300 as a Mediator of SOX2-dependent Squamous Differentiation and Lung Squamous Cell Carcinoma Growth.	PRR12 TCF20 ZNF608 FOXK1	6.39e-06	83	50	4	28794006
Pubmed	The T-box transcription factor Eomes/Tbr2 regulates neurogenesis in the cortical subventricular zone.	SOX1 OTX1 MAP2	8.93e-06	28	50	3	18794345
Pubmed	Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.	ILF3 DDX17 ZNF608 PKP3 GPS2 DVL3 PPIE RFX7 PARD3 CNOT3	9.42e-06	1247	50	10	27684187
Pubmed	hnRNPA1 couples nuclear export and translation of specific mRNAs downstream of FGF-2/S6K2 signalling.	GDF5 DNAJB1 ILF3 DDX17 HRNR FLG2	1.02e-05	346	50	6	25324306
Pubmed	Growth differentiation factor 5 is a key physiological regulator of dendrite growth during development.	GDF5 MAP2	1.21e-05	4	50	2	24173804
Pubmed	Ubiquitin-Independent Disassembly by a p97 AAA-ATPase Complex Drives PP1 Holoenzyme Formation.	PRR12 ILF3 DDX17 MYCBP2 PKP3 PITX1	1.30e-05	361	50	6	30344098
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	ILF3 TCF20 MYCBP2 PKP3 FOSL2 RFX7 PARD3 CNOT3	1.36e-05	774	50	8	15302935
Pubmed	SARS-CoV-2 N Protein Antagonizes Stress Granule Assembly and IFN Production by Interacting with G3BPs to Facilitate Viral Replication.	CARM1 ILF3 DDX17 HRNR FLG2	2.72e-05	245	50	5	35652658
Pubmed	Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.	CARM1 DNAJB1 ILF3 DDX17 KRT75 PKP3 PPIE FAM98A FLG2 FOXK1	2.80e-05	1415	50	10	28515276
Pubmed	Molecular Characterization of the Oncogene BTF3 and Its Targets in Colorectal Cancer.	ILF3 DDX17 PKP3 FAM98A HRNR FLG2 FOXK1	3.02e-05	626	50	7	33644029
Pubmed	Functional roles of a C-terminal signaling complex of CaV1 channels and A-kinase anchoring protein 15 in brain neurons.	ADRB2 MAP2	3.03e-05	6	50	2	21224388
Pubmed	Polysialic acid as an antigen for monoclonal antibody HIgM12 to treat multiple sclerosis and other neurodegenerative disorders.	MAP2 CSPG4	3.03e-05	6	50	2	25866077
Pubmed	Human transcription factor protein interaction networks.	PRR12 TCF20 ZNF608 GPS2 PITX1 HRNR FLG2 RFX7 CNOT3 FOXK1	3.04e-05	1429	50	10	35140242
Pubmed	A non-proteolytic role for ubiquitin in deadenylation of MHC-I mRNA by the RNA-binding E3-ligase MEX-3C.	ILF3 MYCBP2 CNOT3	3.55e-05	44	50	3	26471122
Pubmed	Circular RNA circPVT1 promotes nasopharyngeal carcinoma metastasis via the β-TrCP/c-Myc/SRSF1 positive feedback loop.	ILF3 DDX17 FAM98A HRNR FLG2	3.62e-05	260	50	5	36199071
Pubmed	Suppression of apoptosis impairs phalangeal joint formation in the pathogenesis of brachydactyly type A1.	GDF5 CDON	4.23e-05	7	50	2	38472182
Pubmed	Systematic proteomics of endogenous human cohesin reveals an interaction with diverse splicing factors and RNA-binding proteins required for mitotic progression.	PRR12 DDX17 ZNF608 PKP3 FLG2	4.48e-05	272	50	5	31010829
Pubmed	Spatio-temporal expression pattern of the NatB complex, Nat5/Mdm20 in the developing mouse brain: implications for co-operative versus non-co-operative actions of Mdm20 and Nat5.	SOX1 MAP2	5.64e-05	8	50	2	22101279
Pubmed	RNF43 G659fs is an oncogenic colorectal cancer mutation and sensitizes tumor cells to PI3K/mTOR inhibition.	CARM1 DNAJB1 ILF3 DDX17	6.23e-05	148	50	4	35676246
Pubmed	EGFR suppresses p53 function by promoting p53 binding to DNA-PKcs: a noncanonical regulatory axis between EGFR and wild-type p53 in glioblastoma.	ZNF608 HRNR FLG2	6.59e-05	54	50	3	35474131
Pubmed	The Eyes Absent family members EYA4 and EYA1 promote PLK1 activation and successful mitosis through tyrosine dephosphorylation.	PRR12 ZNF608 GPS2 RFX7	6.91e-05	152	50	4	38360978
Pubmed	PABP1 identified as an arginine methyltransferase substrate using high-density protein arrays.	CARM1 ILF3	7.25e-05	9	50	2	11850402
Pubmed	Foxg1 suppresses early cortical cell fate.	OTX1 MAP2	7.25e-05	9	50	2	14704420
Pubmed	Sox2 induces neuronal formation in the developing mammalian cochlea.	SOX1 MAP2	7.25e-05	9	50	2	20071536
Pubmed	Inhibition of mouse GPM6A expression leads to decreased differentiation of neurons derived from mouse embryonic stem cells.	SOX1 OTX1	7.25e-05	9	50	2	18522499
Pubmed	Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.	CARM1 KLHL3 B3GNT9 ILF3 DDX17 TENT4A DPP8	7.95e-05	730	50	7	34857952
Pubmed	Ubiquitin-assisted phase separation of dishevelled-2 promotes Wnt signalling.	PKP3 DVL3 PARD3 FOXK1	8.63e-05	161	50	4	36398662
Pubmed	Crumbs2 mediates ventricular layer remodelling to form the spinal cord central canal.	SOX1 PARD3	9.05e-05	10	50	2	32150534
Pubmed	The cellular EJC interactome reveals higher-order mRNP structure and an EJC-SR protein nexus.	ILF3 DDX17 KRT75 PPIE	1.04e-04	169	50	4	23084401
Pubmed	A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.	DDX17 PKP3 GPS2 PITX1 DVL3 PJA1 CNOT3 FOXK1	1.08e-04	1038	50	8	26673895
Pubmed	Control of hippocampal morphogenesis and neuronal differentiation by the LIM homeobox gene Lhx5.	OTX1 MAP2	1.10e-04	11	50	2	10325223
Pubmed	A forward genetic screen in mice identifies mutants with abnormal cortical patterning.	CARM1 MYCBP2	1.10e-04	11	50	2	23968836
Pubmed	Temporal and spatial expression patterns of Hedgehog receptors in the developing inner and middle ear.	GDF5 CDON	1.10e-04	11	50	2	29139542
Pubmed	Molecular basis of pituitary dysfunction in mouse and human.	OTX1 PITX1	1.32e-04	12	50	2	11420609
Pubmed	Deletion of Shp2 in the brain leads to defective proliferation and differentiation in neural stem cells and early postnatal lethality.	MAP2 CSPG4	1.32e-04	12	50	2	17646384
Pubmed	A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain.	CARM1 KLHL3 ILF3 RBMXL3 PPIE	1.41e-04	347	50	5	16033648
Pubmed	Nucleolar localization of DGCR8 and identification of eleven DGCR8-associated proteins.	ILF3 DDX17	1.56e-04	13	50	2	17765891
Pubmed	Inactivation of aPKClambda results in the loss of adherens junctions in neuroepithelial cells without affecting neurogenesis in mouse neocortex.	MAP2 PARD3	1.56e-04	13	50	2	16571631
Pubmed	Expression of the homeobox gene Pitx2 in neural crest is required for optic stalk and ocular anterior segment development.	CSPG4 PITX1	1.56e-04	13	50	2	16203745
Pubmed	Cortical and Clonal Contribution of Tbr2 Expressing Progenitors in the Developing Mouse Brain.	SOX1 OTX1	1.56e-04	13	50	2	24927931
Pubmed	Selective ablation of alphav integrins in the central nervous system leads to cerebral hemorrhage, seizures, axonal degeneration and premature death.	MAP2 CSPG4	1.82e-04	14	50	2	15576410
Pubmed	The Tumor Suppressor CIC Directly Regulates MAPK Pathway Genes via Histone Deacetylation.	OTX1 DDX17 PITX1 HRNR FLG2 FOXK1	1.84e-04	583	50	6	29844126
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	ILF3 DDX17 KRT75 ZNF608 CSPG4 FAM98A STOX1 CFAP69 DNAJB14	1.90e-04	1442	50	9	35575683
Pubmed	RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling.	ILF3 DDX17 KRT75 MYCBP2	2.06e-04	202	50	4	24639526
Pubmed	Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations.	KLHL3 OTX1 MORN4 FOSL2 GPS2 PITX1 FAM98A STOX1 CNOT3	2.28e-04	1477	50	9	31515488
Pubmed	Stem cell factor Sox2 and its close relative Sox3 have differentiation functions in oligodendrocytes.	SOX1 CSPG4	2.40e-04	16	50	2	24257626
Pubmed	Enlarged lateral ventricles and aberrant behavior in mice overexpressing PDGF-B in embryonic neural stem cells.	MAP2 CSPG4	2.40e-04	16	50	2	20643125
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	ZNF608 MAP2 MYCBP2 PKP3 FOSL2 KCNN2 PPIE PARD3 CFAP69	2.42e-04	1489	50	9	28611215
Pubmed	Regulation of mouse lens fiber cell development and differentiation by the Maf gene.	SOX1 EYA2	2.72e-04	17	50	2	10603348
Pubmed	Wnts regulate planar cell polarity via heterotrimeric G protein and PI3K signaling.	DVL3 PARD3	2.72e-04	17	50	2	32805026
Pubmed	Myosin-X recruits lamellipodin to filopodia tips.	DNAJB1 MYCBP2 PJA1	2.91e-04	89	50	3	36861887
Pubmed	GREB1: An evolutionarily conserved protein with a glycosyltransferase domain links ERα glycosylation and stability to cancer.	ILF3 PKP3 HRNR FLG2	3.01e-04	223	50	4	33731348
Pubmed	A census of human transcription factors: function, expression and evolution.	FOXE1 SOX1 OTX1 FOSL2 PITX1 RFX7 FOXK1	3.03e-04	908	50	7	19274049
Pubmed	Initiation of olfactory placode development and neurogenesis is blocked in mice lacking both Six1 and Six4.	OTX1 EYA2	3.05e-04	18	50	2	19027001
Pubmed	TRIM25 and DEAD-Box RNA Helicase DDX3X Cooperate to Regulate RIG-I-Mediated Antiviral Immunity.	DDX17 HRNR FLG2	3.11e-04	91	50	3	34445801
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	PRR12 TCF20 ZNF608 MYCBP2 DVL3	3.33e-04	418	50	5	34709266
Pubmed	Msx1-Positive Progenitors in the Retinal Ciliary Margin Give Rise to Both Neural and Non-neural Progenies in Mammals.	OTX1 CDON	3.41e-04	19	50	2	28011038
Pubmed	Gli3 is required for the specification and differentiation of preplate neurons.	MAP2 PARD3	3.41e-04	19	50	2	16168404
Pubmed	Requirement for Lmo4 in the vestibular morphogenesis of mouse inner ear.	OTX1 EYA2	3.41e-04	19	50	2	19913004
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	ILF3 DDX17 HRNR FLG2	3.61e-04	234	50	4	36243803
Pubmed	Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells.	DDX17 KRT75 FAM98A HERC4 CNOT3 FOXK1	3.71e-04	665	50	6	30457570
Pubmed	Transcriptional regulation of cortical neuron migration by POU domain factors.	OTX1 MAP2	3.79e-04	20	50	2	11859196
Pubmed	A single cell transcriptional atlas of early synovial joint development.	GDF5 MFAP4	3.79e-04	20	50	2	32580935
Pubmed	Molecular characterization of a novel transcription factor that controls stromelysin expression.	OTX1 TCF20	3.79e-04	20	50	2	7760812
Pubmed	DDX24 promotes metastasis by regulating RPL5 in non-small cell lung cancer.	KRT75 PKP3 HRNR FLG2	3.85e-04	238	50	4	35864588
Pubmed	AMP-activated protein kinase phosphorylates retinoblastoma protein to control mammalian brain development.	MAP2 PARD3	4.18e-04	21	50	2	19217427
Pubmed	Variation in genes of the epidermal differentiation complex in German atopic dermatitis patients.	HRNR FLG2	4.18e-04	21	50	2	19601998
Pubmed	Mutually regulated expression of Pax6 and Six3 and its implications for the Pax6 haploinsufficient lens phenotype.	SOX1 EYA2	4.18e-04	21	50	2	12072567
Pubmed	Targeted proteomic analysis of 14-3-3 sigma, a p53 effector commonly silenced in cancer.	MYCBP2 PKP3 PARD3	4.34e-04	102	50	3	15778465
Pubmed	An adhesion signaling axis involving Dystroglycan, β1-Integrin, and Cas adaptor proteins regulates the establishment of the cortical glial scaffold.	MAP2 CSPG4	4.59e-04	22	50	2	37540708
Pubmed	DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity.	CARM1 PRR12 ILF3 TCF20 FOSL2	4.80e-04	453	50	5	29656893
Pubmed	Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation.	CARM1 PRR12 TCF20 PKP3 FOXK1	4.99e-04	457	50	5	32344865
Pubmed	Draxin from neocortical neurons controls the guidance of thalamocortical projections into the neocortex.	MAP2 CSPG4	5.03e-04	23	50	2	26659141
Pubmed	Tbr1 regulates differentiation of the preplate and layer 6.	OTX1 MAP2	5.03e-04	23	50	2	11239428
Pubmed	The Rho-GTPase cdc42 regulates neural progenitor fate at the apical surface.	MAP2 PARD3	5.48e-04	24	50	2	16892058
Pubmed	Neurofibromatosis-1 regulates neuronal and glial cell differentiation from neuroglial progenitors in vivo by both cAMP- and Ras-dependent mechanisms.	MAP2 CSPG4	5.48e-04	24	50	2	18371380
Pubmed	Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling.	TENT4A MYCBP2 GAB4 PARD3	5.76e-04	265	50	4	19240061
Pubmed	ACAA2 is a ligand-dependent coactivator for thyroid hormone receptor β1.	KRT75 MAP2 CSPG4	5.86e-04	113	50	3	34474245
Pubmed	Rheb1 is required for mTORC1 and myelination in postnatal brain development.	MAP2 CSPG4	5.95e-04	25	50	2	21238928
Pubmed	Brain development is impaired in c-fos -/- mice.	MAP2 FOSL2	5.95e-04	25	50	2	26143639
Pubmed	Regulation of planar cell polarity by Smurf ubiquitin ligases.	DVL3 PARD3	5.95e-04	25	50	2	19379695
Pubmed	Delineating the early transcriptional specification of the mammalian trachea and esophagus.	FOXE1 PITX1	5.95e-04	25	50	2	32515350
Pubmed	LRP2 Acts as SHH Clearance Receptor to Protect the Retinal Margin from Mitogenic Stimuli.	OTX1 CDON	6.44e-04	26	50	2	26439398
Pubmed	Transcriptional regulatory networks in epiblast cells and during anterior neural plate development as modeled in epiblast stem cells.	SOX1 OTX1	6.44e-04	26	50	2	22992956
Pubmed	Regulation of differentiation flux by Notch signalling influences the number of dopaminergic neurons in the adult brain.	SOX1 MAP2	6.44e-04	26	50	2	26912775
Pubmed	mTORC1 activity regulates post-translational modifications of glycine decarboxylase to modulate glycine metabolism and tumorigenesis.	CARM1 ILF3 DDX17 TCF20	6.53e-04	274	50	4	34244482
Pubmed	Brg1 coordinates multiple processes during retinogenesis and is a tumor suppressor in retinoblastoma.	EYA2 PARD3	6.95e-04	27	50	2	26628093
Pubmed	Mapping the Ku Interactome Using Proximity-Dependent Biotin Identification in Human Cells.	DNAJB1 ILF3 DDX17 TCF20	7.36e-04	283	50	4	30585729
Interaction	PAX9 interactions	PRR12 TCF20 ZNF608 GPS2 EYA2 FOXK1	7.15e-07	130	49	6	int:PAX9
Interaction	SOX17 interactions	PRR12 ILF3 TCF20 GPS2 HRNR	3.39e-06	95	49	5	int:SOX17
Interaction	TBR1 interactions	PRR12 ZNF608 MYCBP2 PITX1 FOXK1	7.94e-06	113	49	5	int:TBR1
Interaction	NIPAL2 interactions	ADRB2 NIPAL2	1.73e-05	3	49	2	int:NIPAL2
Interaction	SOX2 interactions	SOX1 PRR12 MFAP4 ILF3 DDX17 TCF20 ZNF608 PKP3 GPS2 PITX1 FAM98A CNOT3 FOXK1	2.43e-05	1422	49	13	int:SOX2
Interaction	EYA4 interactions	PRR12 ZNF608 GPS2 DVL3 EYA2 RFX7	2.62e-05	243	49	6	int:EYA4
Interaction	TLE3 interactions	PRR12 MFAP4 DDX17 TCF20 ZNF608 GPS2 EYA2	3.26e-05	376	49	7	int:TLE3
Interaction	MEX3C interactions	ILF3 MYCBP2 PPIE CNOT3	5.16e-05	84	49	4	int:MEX3C
Interaction	EWSR1 interactions	PRR12 DNAJB1 OTX1 ILF3 DDX17 TCF20 MYCBP2 PITX1 PPIE HRNR	5.34e-05	906	49	10	int:EWSR1
Interaction	IRF4 interactions	CARM1 PRR12 TCF20 ZNF608	5.40e-05	85	49	4	int:IRF4
Interaction	WDR4 interactions	CARM1 DNAJB1 DDX17 DPP8	6.47e-05	89	49	4	int:WDR4
Interaction	RNF43 interactions	CARM1 DNAJB1 ILF3 DDX17 TCF20 DVL3 PARD3	7.27e-05	427	49	7	int:RNF43
Interaction	CUL2 interactions	CARM1 ILF3 DDX17 ADRB2 KRT75 FAM98A HRNR FLG2	8.15e-05	591	49	8	int:CUL2
Interaction	SP7 interactions	PRR12 TCF20 ZNF608 GPS2 PITX1 FOXK1	9.09e-05	304	49	6	int:SP7
Interaction	KLF5 interactions	PRR12 ZNF608 HRNR FLG2 FOXK1	1.09e-04	195	49	5	int:KLF5
Interaction	DTX2 interactions	PRR12 TCF20 PKP3 GPS2 EYA2 RFX7	1.42e-04	330	49	6	int:DTX2
Interaction	DDX3X interactions	ILF3 DDX17 MYCBP2 PPIE FAM98A HRNR FLG2 CNOT3	1.59e-04	651	49	8	int:DDX3X
Interaction	PSMB11 interactions	ILF3 PITX1	1.61e-04	8	49	2	int:PSMB11
Interaction	TBXT interactions	PRR12 TCF20 ZNF608 GPS2	1.81e-04	116	49	4	int:TBXT
Interaction	ICAM4 interactions	MYCBP2 DPP8 SLC5A4	1.91e-04	46	49	3	int:ICAM4
Interaction	EGLN3 interactions	CARM1 DNAJB1 ADRB2 MYCBP2 GPS2 PITX1 DVL3 PJA1 PARD3 CNOT3 FOXK1	2.25e-04	1296	49	11	int:EGLN3
Interaction	KLF3 interactions	ZNF608 GPS2 DVL3 RFX7 FOXK1	2.26e-04	228	49	5	int:KLF3
Interaction	TRIM23 interactions	MORN4 KRT75 MYOZ1 PITX1 PJA1 HRNR	2.28e-04	360	49	6	int:TRIM23
Interaction	YWHAH interactions	DNAJB1 ILF3 TCF20 MAP2 MYCBP2 FAM98A DPP8 RFX7 PARD3 FOXK1	2.68e-04	1102	49	10	int:YWHAH
GeneFamily	EF-hand domain containing\|S100 fused type protein family	HRNR FLG2	8.50e-05	7	37	2	1350
Coexpression	GSE23502_BM_VS_COLON_TUMOR_MYELOID_DERIVED_SUPPRESSOR_CELL_DN	DDX17 ADRB2 ZNF608 RFX7 HERC4 FOXK1	2.20e-06	200	50	6	M8088
Coexpression	GSE15930_NAIVE_VS_24H_IN_VITRO_STIM_CD8_TCELL_UP	ADRB2 TCF20 PKP3 EYA2 FOXK1	3.94e-05	200	50	5	M3587
Coexpression	GSE15930_NAIVE_VS_24H_IN_VITRO_STIM_IL12_CD8_TCELL_UP	ADRB2 TCF20 PKP3 EYA2 FOXK1	3.94e-05	200	50	5	M3589
Coexpression	GSE15930_NAIVE_VS_24H_IN_VITRO_STIM_INFAB_CD8_TCELL_UP	ADRB2 TCF20 PKP3 EYA2 FOXK1	3.94e-05	200	50	5	M3593
ToppCell	5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	OTX1 PKP3 PITX1 NIPAL2 EYA2	2.90e-06	199	50	5	6977f939ddbc47d4921f36c0a61a205259fe1284
ToppCell	5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)-Club_(nasal)_L.0.2.1.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	OTX1 PKP3 PITX1 NIPAL2 EYA2	2.90e-06	199	50	5	ba284f984909504221900bca5ea12ada5b2ffd9f
ToppCell	5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	OTX1 PKP3 PITX1 NIPAL2 EYA2	2.90e-06	199	50	5	fbd39d34636137d1b877dd8815d58f124990136b
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW09\|fetalBrain_Zhong_nature / Sample Type, Dataset, Time_group, and Cell type.	DNAJB1 MFAP4 OTX1 STOX1 EYA2	2.90e-06	199	50	5	399e73d45638848e68edda120316ceff04d98680
ToppCell	5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)-Club_(nasal)_L.0.2.1.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	OTX1 PKP3 PITX1 NIPAL2 EYA2	2.97e-06	200	50	5	8c4c396e99be6131a8fa60d86214d561031b12bf
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW09\|organoid_Tanaka_cellReport / Sample Type, Dataset, Time_group, and Cell type.	DNAJB1 MFAP4 OTX1 STOX1 EYA2	2.97e-06	200	50	5	c792d1dbbe27ebd60f4770834f30882c1a625be5
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c07-AHNAK\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	DNAJB1 FOSL2 PJA1 FLG2	4.05e-05	171	50	4	7b0783d25055e5ea5b2fc44ebcb16bfd0adbcf81
ToppCell	wk_20-22-Epithelial-Proximal_epithelial-basal_late\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	OTX1 PKP3 PITX1 EYA2	4.73e-05	178	50	4	03f22485074b3cbf9a6ad4d543c5bbfa826dc741
ToppCell	Control-Epithelial-Basal\|Control / Disease state, Lineage and Cell class	FOXE1 PITX1 EYA2 PARD3	5.16e-05	182	50	4	caddd0a52f0234ea6a916186ffaf2454cdcd80ee
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_chondroblast_(18)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	GDF5 ADRB2 CSPG4 CDON	6.22e-05	191	50	4	f9a46956778a8773d6656340ecf5d218376d79c2
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_chondroblast_(18)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	GDF5 DNAJB1 MAP2 EYA2	6.35e-05	192	50	4	d0649410cf5eacdb0c1dce70e37c7473ef5fddfa
ToppCell	Transplant_Alveoli_and_parenchyma-Mesenchymal-Smooth_muscle\|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X	MFAP4 MYOZ1 MAP2 CSPG4	6.48e-05	193	50	4	9104b572d9c3c99080e4b7455993fbb944bf117d
ToppCell	10x3'2.3-week_17-19-Mesenchymal_fibro-stroma-endosteal_fibroblast\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	GDF5 CSPG4 PITX1 CDON	6.61e-05	194	50	4	69362e13158033de44f90f3773db6c0f27de8cb3
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Degenerative_Vascular_Smooth_Muscle_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MFAP4 MYOZ1 MAP2 CSPG4	6.61e-05	194	50	4	5099e6ad7c19e5f8b73449d904aaefd97f1b1959
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Degenerative_Vascular_Smooth_Muscle_Cell-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MFAP4 MYOZ1 MAP2 CSPG4	6.61e-05	194	50	4	71734ef7b34ab33b349595368176fa0e1175d4d0
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MFAP4 MYOZ1 MAP2 CSPG4	6.74e-05	195	50	4	e10b21e4dba4483efc4c82d6e395524246ca14a8
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MFAP4 MYOZ1 MAP2 CSPG4	6.74e-05	195	50	4	9ab3c5b0fb12d406408122a535b717bfe184bbcf
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MFAP4 MYOZ1 MAP2 CSPG4	6.74e-05	195	50	4	21263d138c81f6a0219f2cd93126cfafd35732b2
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.1.3\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FOXE1 PKP3 PITX1 PARD3	7.01e-05	197	50	4	233b9fcb376e08d0080a05ca0198ecc6ec720f90
ToppCell	3'-GW_trimst-2-SmallIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DNAJB1 MFAP4 PITX1 PJA1	7.01e-05	197	50	4	888f3b14133e078570ce4ad73d9a9ee3137f9cac
ToppCell	facs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l1\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GDF5 MFAP4 B3GNT9 CSPG4	7.01e-05	197	50	4	3fe665c0277d091290b63f0dd24c0c6536a45309
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.1.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PKP3 PITX1 EYA2 PARD3	7.15e-05	198	50	4	9718f4c013c347f1b3c785ae232dd2fb6c1fe298
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_airway_basal-Suprabasal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FOXE1 OTX1 STOX1 EYA2	7.15e-05	198	50	4	28ada093cec552262731194a04a4b9ff93186c3b
ToppCell	cellseq-Epithelial-Epithelial_Airway-Basal/Suprabasal-Basal\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	FOXE1 OTX1 PITX1 EYA2	7.15e-05	198	50	4	7063d74d79f53d5c59c853a2575f9d3ef12f19ea
ToppCell	Non-neuronal-Non-dividing-Radial_Glia-early\|World / Primary Cells by Cluster	DNAJB1 OTX1 STOX1 CDON	7.29e-05	199	50	4	549391e7a4285da1c0e366654530bcf1cd33fbae
ToppCell	Non-neuronal-Non-dividing-Radial_Glia-early-40\|World / Primary Cells by Cluster	DNAJB1 OTX1 STOX1 CDON	7.29e-05	199	50	4	23625d757173bdd35a51c7919ff4b588168d2553
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_2_(ZEB2+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DNAJB1 MFAP4 PITX1 PJA1	7.29e-05	199	50	4	a95aa72387c9558e0316898eaa9df4de8932af1b
ToppCell	distal-1-Epithelial-Differentiating_Basal\|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	DNAJB1 PITX1 XG EYA2	7.29e-05	199	50	4	fe7d6f70fe337b91b0ad63ea33e5a714d2df87bd
ToppCell	10x3'2.3-week_17-19-Mesenchymal_fibro-stroma\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	B3GNT9 CSPG4 PITX1 CDON	7.44e-05	200	50	4	747c61d4e0b746278ae1f45ca4cd556c6961c76a
ToppCell	Bronchial-10x5prime-Epithelial-Epi_airway_basal\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	FOXE1 PKP3 PITX1 EYA2	7.44e-05	200	50	4	afac850d5a40de0d6f02857cf81a19443d90b1eb
ToppCell	Neuronal-Inhibitory-iB-iB_4(SST)-CALB1--L1-3\|Neuronal / cells hierarchy compared to all cells using T-Statistic	SOX1 ZNF608 EYA2 PARD3	7.44e-05	200	50	4	f3c710f0fc8a7bfb5371d1aff6e3d8f266953153
ToppCell	Neuronal-Inhibitory-iB-iB_4(SST)-CALB1\|Neuronal / cells hierarchy compared to all cells using T-Statistic	SOX1 ZNF608 EYA2 PARD3	7.44e-05	200	50	4	1639982d9d994918f7912d12d9d7cfcbc9da4145
ToppCell	LPS_only-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_only / Treatment groups by lineage, cell group, cell type	MFAP4 DDX17 MYCBP2 EYA2	7.44e-05	200	50	4	a7ef7022b8efcaedb7319b0b43d8c4e99d788fe2
ToppCell	Neuronal-Inhibitory-iB-iB_4(SST)-CALB1-\|Neuronal / cells hierarchy compared to all cells using T-Statistic	SOX1 ZNF608 EYA2 PARD3	7.44e-05	200	50	4	70a06fd7fb8de2c8ec3e3182e4476ced049daeae
ToppCell	Sigmoid-T_cell-Tfh\|T_cell / Region, Cell class and subclass	KLHL3 B3GNT9 MORN4 MAP2	7.44e-05	200	50	4	dd7dcf25520f065bf0d33d589f3c176f63875dc9
ToppCell	10x3'2.3-week_17-19-Mesenchymal_fibro\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	B3GNT9 CSPG4 PITX1 CDON	7.44e-05	200	50	4	de1d193f773f4e2927baa6fc38d29754b015c6e6
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-CR\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	GDF5 PKP3 EYA2	1.11e-04	83	50	3	1ab68323518adc7fd0a459b41fad12d60f97eb5c
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-CR-CR_Lhx5\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	GDF5 PKP3 EYA2	1.11e-04	83	50	3	75b27d91a4473286f4b40027e96ac5246f5abe5b
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L6_CT-L6_CT_ALM_Nxph2_Sla\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	MFAP4 OTX1 KRT75	1.77e-04	97	50	3	0d68bf2dfb9c221375b70b055f735536afb18f65
ToppCell	AT2_cells-IPF_02\|World / lung cells shred on cell class, cell subclass, sample id	FOXE1 OTX1 EYA2	4.28e-04	131	50	3	ff4e618bd944f852bbd34438f740187aca82460f
ToppCell	Smart-seq2-thymus_(Smart-seq2)-lymphocytic-T_lymphocytic\|thymus_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	DPP8 DNAJB14 SLC5A4	4.28e-04	131	50	3	1be75b37d87942941f6f46009373d79647107ca9
ToppCell	Smart-seq2-thymus_(Smart-seq2)-lymphocytic-T_lymphocytic-CD4-positive_helper_T_cell\|thymus_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	DPP8 DNAJB14 SLC5A4	4.28e-04	131	50	3	c84d4c764482353ba226f8707f736260da9dff13
ToppCell	Cerebellum-Endothelial-ENDOTHELIAL_TIP-Dcn_1\|Cerebellum / BrainAtlas - Mouse McCarroll V32	GDF5 MFAP4 EYA2	4.57e-04	134	50	3	d29ac8152dc581c0da2430d06cd259ac0eded808
ToppCell	Cerebellum-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1\|Cerebellum / BrainAtlas - Mouse McCarroll V32	GDF5 MFAP4 EYA2	4.57e-04	134	50	3	459c39df15d3cf9144ce7827e8d14830d31353bb
ToppCell	Cerebellum-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Apod_(Apod)-\|Cerebellum / BrainAtlas - Mouse McCarroll V32	GDF5 MFAP4 EYA2	4.57e-04	134	50	3	d065449ca3679e4818b74fb7302cc7f1ce62f691
ToppCell	Cerebellum-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Apod_(Apod)\|Cerebellum / BrainAtlas - Mouse McCarroll V32	GDF5 MFAP4 EYA2	4.57e-04	134	50	3	0be389f416818a22e80098dd809fdf45b14171e8
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Serpinf1-Serpinf1_Aqp5_Vip\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	SOX1 FOSL2 KCNN2	4.77e-04	136	50	3	8f5682422ba0b477c1e0700212948457f106cb10
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW16-OPC_related-Oligodendrocyte/OPC\|GW16 / Sample Type, Dataset, Time_group, and Cell type.	MFAP4 NIPAL2 EYA2	5.41e-04	142	50	3	43e72e4b9ae33768672ef90c8bbfd2ca1818c746
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW16-OPC_related\|GW16 / Sample Type, Dataset, Time_group, and Cell type.	MFAP4 NIPAL2 EYA2	5.41e-04	142	50	3	d2d150e3019a5b7b143e50b1c1c2b6764abf36bf
ToppCell	343B-Myeloid-Macrophage-SPP1+_Macrophage_2\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	MORN4 TCF20 PPIE	6.35e-04	150	50	3	744050a1b665c6989f37141348af3df7579a73c9
ToppCell	PND01-03-samps-Epithelial-Alveolar_epithelial-AT1_-_meso\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	PKP3 EYA2 FLG2	6.35e-04	150	50	3	6a13e4c4b9c9e54a5016573a37132465ec1c8f99
ToppCell	21-Trachea-Epithelial-Submucosal_gland_basal\|Trachea / Age, Tissue, Lineage and Cell class	MYOZ1 MAP2 CSPG4	7.51e-04	159	50	3	4f670b57b8d3b090ea2f1aafe15baf93cb7ef146
ToppCell	facs-Lung-Endomucin-3m-Lymphocytic-CD4+_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TCF20 TENT4A EYA2	7.65e-04	160	50	3	5c68d6a76c59e3a7e668ae5471396478a55756ac
ToppCell	facs-Lung-Endomucin-3m-Lymphocytic-CD4-positive,_alpha-beta_T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TCF20 TENT4A EYA2	7.65e-04	160	50	3	0fee84844733d36805e1df90ca09478169746708
ToppCell	P07-Mesenchymal-developing_mesenchymal_cell-mesenchymal_mature_unknown_2\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	GDF5 MFAP4 MYOZ1	7.65e-04	160	50	3	68b477525eeef99430382ff0a6745cac91364bc2
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-stromal_related-ICC\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	KCNN2 EYA2 CDON	7.79e-04	161	50	3	deb10628d258fb813c293f81fb71be8e383dc82a
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-stromal_related\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	KCNN2 EYA2 CDON	7.79e-04	161	50	3	8aaca49b53a551395f4025ac4e535c7b0ce41a49
ToppCell	10x5'-Liver-Lymphocytic_Invariant-Inducer-like-ILC3\|Liver / Manually curated celltypes from each tissue	ZNF608 CSPG4 CFAP69	8.07e-04	163	50	3	7f61483eeb1fde21843c6391468e13cb0cc2a89f
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-Degenerative_Endothelial_Cell-Degenerative_Peritubular_Capilary_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	GPS2 PITX1 SLC5A4	8.07e-04	163	50	3	73c03e29a6d7a6863c5e9aa5e8b963ef691f1ddb
ToppCell	5'-GW_trimst-2-SmallIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_1_(HAND1+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MFAP4 PITX1 PJA1	8.22e-04	164	50	3	72ef807895385ba23e30d19d12b1b0549a699690
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MFAP4 PITX1 PJA1	8.66e-04	167	50	3	b742558ca92985db0a67c88f530bc375f3d3bb98
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma-9\|TCGA-Brain / Sample_Type by Project: Shred V9	ADRB2 STOX1 PARD3	8.66e-04	167	50	3	013971700e80b71e4b8c79b8fff0d8beeac295c3
ToppCell	10x5'-Lung-Lymphocytic_B_plasma-Plasma_cells\|Lung / Manually curated celltypes from each tissue	MORN4 PITX1 CFAP69	8.81e-04	168	50	3	e8bd090de5c9fe286b08a8b314ce12cf988184f0
ToppCell	facs-Aorta-Heart-24m-Mesenchymal-fibroblast_of_cardiac_tissue\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX1 CSPG4 PITX1	8.96e-04	169	50	3	daed9083ee05c220365200328c2c50047fe21efd
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1-AT1_L.0.5.1.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAJB1 ADRB2 MAP2	8.96e-04	169	50	3	cd16e8462ee09877be962fbd9a3badcb825820b0
ToppCell	5'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FOXE1 OTX1 FLG2	9.12e-04	170	50	3	2d880223d01bde4bf777bd6f50b7d2768489075f
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DNAJB1 PITX1 PJA1	9.12e-04	170	50	3	a7184dc41f90caa753860ed0f65a18133f84bc5f
ToppCell	15-Airway-Epithelial-Club-like_secretory\|Airway / Age, Tissue, Lineage and Cell class	OTX1 PKP3 PITX1	9.12e-04	170	50	3	1418031cc4b4a87a48621eb53a3c819cd713ddd0
ToppCell	5'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting-Basal_resting_L.0.0.0.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FOXE1 OTX1 FLG2	9.12e-04	170	50	3	0cc20322cb3e3e7bbd4daad8785c99f80e355c16
ToppCell	facs\|World / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ILF3 TCF20 DVL3	9.27e-04	171	50	3	c9990bc041a632b2f7bbebbfe737772c423d7027
ToppCell	3'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature-ENCC/glia_Progenitor\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MAP2 STOX1 RFX7	9.27e-04	171	50	3	b51bbeacb172e8b5de519ada85543d7ae9914b3c
ToppCell	10x5'-Lung-Lymphocytic_B_plasma\|Lung / Manually curated celltypes from each tissue	MORN4 PITX1 CFAP69	9.43e-04	172	50	3	8156fb6de66a4c92ade703b71c2e9187291e50ef
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MFAP4 HRNR SLC5A4	9.43e-04	172	50	3	1ef243bce63d841c25e4b74d029d1377f84bcc3d
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1_VIP_PCDH20\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SOX1 ZNF608 PARD3	9.43e-04	172	50	3	35e961c88bfe79046533396912cedf00ca81db7b
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MFAP4 HRNR SLC5A4	9.43e-04	172	50	3	ab1c81be29f93ca8920c6ab5ab92f497a9256d3f
ToppCell	droplet-Lung-nan-3m-Myeloid-plasmacytoid_dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ILF3 MAP2 PKP3	9.59e-04	173	50	3	1b9b4e165121b08ef15a93fca6bea875cae69f19
ToppCell	droplet-Lung-nan-3m-Myeloid-Plasmacytoid_Dendritic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ILF3 MAP2 PKP3	9.59e-04	173	50	3	c25f24d7b672c9686d31ebc8d263042282f520fd
ToppCell	Children_(3_yrs)-Epithelial-lung_goblet_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	PITX1 STOX1 EYA2	9.59e-04	173	50	3	464267a2ff3f5c387b6c9c6fa4dab135a221f448
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-5w-Mesenchymal-Cilia-bearing_cell\|5w / Sample Type, Dataset, Time_group, and Cell type.	GDF5 KLHL3 MYOZ1	9.59e-04	173	50	3	d4cbeae262abfa30d8c5452285d3261a96875610
ToppCell	facs-Heart-RV-18m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAP2 CSPG4 KCNN2	9.91e-04	175	50	3	d8e385320f554d974538b7cdc4f8e4767f1455f2
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L2-6_VIP_VIP\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SOX1 ZNF608 PARD3	9.91e-04	175	50	3	e78bf0c33a741bb97e987e41ac33da9e623a08ec
ToppCell	facs-Heart-RV-18m-Myeloid\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADRB2 PKP3 NIPAL2	9.91e-04	175	50	3	bde002379088c0407afd0f3dae60b6a166683957
ToppCell	facs-Heart-RV-18m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAP2 CSPG4 KCNN2	9.91e-04	175	50	3	cf15465855602ba135752c18755e3e058dbd42ec
ToppCell	TCGA-Cervix-Primary_Tumor-Cervical_Carcinoma-Non-keratinizing_Cervical_Squamous_Cell_Carcinoma-3\|TCGA-Cervix / Sample_Type by Project: Shred V9	MYCBP2 NIPAL2 PARD3	9.91e-04	175	50	3	0cc215109d9915af47e4d0a120ce2e46910715fa
ToppCell	wk_15-18-Epithelial-Proximal_epithelial-Proximal_secretory_3\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	OTX1 PKP3 PITX1	1.01e-03	176	50	3	8d9d0fb46c418b2067be58aec822e8c2b1561461
ToppCell	wk_15-18-Epithelial-Proximal_epithelial-SMG_basal_2\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	PKP3 CSPG4 PITX1	1.01e-03	176	50	3	045b12c90f7dd49a9778dadcdf8f18125b380531
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L2-5_VIP_TOX2\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SOX1 ZNF608 PARD3	1.02e-03	177	50	3	85e270b4a0b0da77ffe5987a099e827c02a4adf3
ToppCell	droplet-Lung-nan-3m-Mesenchymal-pericyte_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GDF5 MORN4 CSPG4	1.02e-03	177	50	3	65709bd546cb1ec6aa2ddd8b2adb46e174eb9a9a
ToppCell	10x3'2.3-week_17-19-Mesenchymal_osteo-stroma-chondrocyte\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	GDF5 CSPG4 PITX1	1.02e-03	177	50	3	915b848d789051a1c3bc6f6dc86955bb752276ab
ToppCell	nucseq-Epithelial-Epithelial_Airway-Basal/Suprabasal-Basal\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	FOXE1 PITX1 EYA2	1.02e-03	177	50	3	ce86dfaeb74d995a19aea62f0fb15c4c0bb854b0
ToppCell	nucseq-Epithelial-Epithelial_Airway-Basal/Suprabasal\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	FOXE1 PITX1 EYA2	1.02e-03	177	50	3	cbad1a23851151dbef01ea2af960e6f0944f838b
ToppCell	droplet-Lung-nan-3m-Mesenchymal-Pericyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GDF5 MORN4 CSPG4	1.02e-03	177	50	3	8684d47a547e2a06496f15e8da0200ecddc431e0
ToppCell	facs-Lung-3m-Epithelial-airway_epithelial-respiratory_basal_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	OTX1 PITX1 EYA2	1.04e-03	178	50	3	fb8f8d95f6b08378fb42c4076ee040276faa296f
ToppCell	wk_20-22-Epithelial-Proximal_epithelial-basal_proximal\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	OTX1 PITX1 EYA2	1.04e-03	178	50	3	9534c4f4e950bb1498c1737ca1713e7f37d0aff2
ToppCell	facs-Lung-3m-Epithelial-airway_epithelial-respiratory_basal_cell-basal_epithelial_cell_of_bronchioalveolar_tree\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	OTX1 PITX1 EYA2	1.04e-03	178	50	3	b89c4d015b44bf538aa39969ef8778877c8023f1
ToppCell	TCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Ductal_Carcinoma-4\|TCGA-Breast / Sample_Type by Project: Shred V9	GDF5 OTX1 MAP2	1.04e-03	178	50	3	44b5ba4e8788d3973749a1717e427647ac4c8579
ToppCell	5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1-AT1_L.0.5.1.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAJB1 ADRB2 MAP2	1.06e-03	179	50	3	d5e3e7f1cd8f683f39a7416f12af7e766dcbead8
ToppCell	droplet-Lung-nan-18m-Lymphocytic-Ly6g5b+_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PKP3 EYA2 PARD3	1.07e-03	180	50	3	81c7086399256260e59424b7410feec514ce8027
ToppCell	Bronchial_Biopsy-Mesenchymal-Smooth_muscle\|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X	MFAP4 MYOZ1 CSPG4	1.07e-03	180	50	3	7085a851807e6a833965e1366946db0bbc5174e2
ToppCell	facs-Brain_Non-Myeloid-Hippocampus_-18m-Epithelial-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT75 PKP3 CDON	1.09e-03	181	50	3	a5e770b5b5d57cbac18560828e89f7c96b687743
Drug	Cefsulodin sodium salt [52152-93-9]; Down 200; 7.2uM; MCF7; HT_HG-U133A	DDX17 FOSL2 PITX1 DVL3 PARD3 HERC4	3.87e-06	196	49	6	4148_DN
Drug	Chlorpheniramine maleate [113-92-8]; Down 200; 10.2uM; MCF7; HT_HG-U133A	DDX17 MYOZ1 KCNN2 NIPAL2 HERC4 CDON	4.11e-06	198	49	6	2217_DN
Disease	lysophosphatidylcholine 20:4 measurement	MYCBP2 EYA2	1.30e-03	32	49	2	EFO_0010363
Disease	cognitive function measurement, self reported educational attainment	PRR12 TCF20 MYCBP2 DPP8	2.85e-03	355	49	4	EFO_0004784, EFO_0008354
Disease	sleep duration	PRR12 MAP2 MYCBP2 KCNN2	3.06e-03	362	49	4	EFO_0005271

Protein segments in the cluster

Peptide	Gene	Start	Entry
GNGYSSNGNTGEQSG	ADRB2	351	P07550
AGQLVYAHGGGGTQQ	CSPG4	1781	Q6UVK1
EHGQFQGSPGGAYGT	GPS2	176	Q13227
LGYSYGGGSASSQHS	DVL3	556	Q92997
SGGGANGTSFSYTFH	DNAJB1	81	P25685
AGGGAGKQNGATSYS	CNOT3	416	O75175
YDQHGSSSGKTSGFG	FLG2	466	Q5D862
HGSGSSQSSGYGQYG	FLG2	546	Q5D862
GLGSGQSTGFGQYGS	FLG2	571	Q5D862
GQYGSGSGQSSGFGQ	FLG2	581	Q5D862
GFGQHGSGSSQSTGF	FLG2	641	Q5D862
GQYGSGSGQSSGFGQ	FLG2	656	Q5D862
HGFGSSQSSGYGQHG	FLG2	696	Q5D862
YGQHGSSSGQTSGFG	FLG2	706	Q5D862
SFGQHGSGSGQSSGF	FLG2	731	Q5D862
SGYGQHGSRQTSGFG	FLG2	781	Q5D862
QHGSGSSQSTGFGQY	FLG2	796	Q5D862
GFGQYGSGSGQSAGF	FLG2	806	Q5D862
GQHGSGSSQSSGYGQ	FLG2	846	Q5D862
FGQHRSSSGQYSGFG	FLG2	871	Q5D862
SSSGQYSGFGQHGSG	FLG2	876	Q5D862
YSGFGQHGSGSGQSS	FLG2	881	Q5D862
GFGQHGTGSGQYSGF	FLG2	896	Q5D862
GTGSGQYSGFGQHES	FLG2	901	Q5D862
GQHGSSSGQTFGFGQ	FLG2	936	Q5D862
FGFGQHRSGSGQSSG	FLG2	946	Q5D862
FGQHGSGSGQSSGFG	FLG2	961	Q5D862
GYGQHGSSSGQTTGF	FLG2	1011	Q5D862
SSGQYSGFGQHGSGS	FLG2	1031	Q5D862
FGQHGTGSGQSSGFG	FLG2	1051	Q5D862
YGQHGSGSSQSSGYG	FLG2	1076	Q5D862
GQYGSGSGQSSGFGQ	FLG2	1116	Q5D862
TYGQTGEATGHGHSG	FLG2	1391	Q5D862
GGHSYGGGATNANAR	GDF5	61	P43026
SNNLALYGTGGGGST	KCNN2	76	Q9H2S1
AQGSGGGSTSAHYAV	CARM1	566	Q86X55
FGAGGYGQLGHNSTS	HERC4	266	Q5GLZ8
GSGSGQSPNYGQHGS	HRNR	196	Q86YZ3
GHYESGSGQTSGFGQ	HRNR	336	Q86YZ3
QHGTGFGRSSSSGPY	HRNR	441	Q86YZ3
FGHKSGSGQSSGYSQ	HRNR	701	Q86YZ3
GFGQHESGSGQGYSQ	HRNR	816	Q86YZ3
ESGSGQGYSQHGSAS	HRNR	821	Q86YZ3
SSGYGRHGAGSGQSP	HRNR	1346	Q86YZ3
SSGYGRHGAGSGQSL	HRNR	2756	Q86YZ3
GQHGSGSGQSSGYSQ	HRNR	2786	Q86YZ3
SGYSQHGSGSGQDGY	HRNR	2796	Q86YZ3
GSNHDGGSSGSYFLS	HRNR	2816	Q86YZ3
GGFGFSVTHGNQGPF	PDZD3	231	Q86UT5
HGHTQGGGYSSVGSG	TENT4A	721	Q5XG87
HQGYGGSGLAFNSAD	OTX1	301	P32242
FGGGFPSGSVHSFSN	DNAJB14	206	Q8TBM8
NEASSGKYTQHGGGN	GAB4	311	Q2WGN9
YHQGSGTFLFQAGSG	DPP8	171	Q6V1X1
VNGSLNGGLYSGHSN	CDON	1061	Q4KMG0
KFNYSGSGGRSGGNS	ILF3	806	Q12906
AHAESYSSGGGGQQK	FOSL2	21	P15408
NGYILTSQGAAGGSH	FOXK1	536	P85037
GVLSGQLYATGGHDG	KLHL3	486	Q9UH77
GSGYGSPNSAFGAQA	DDX17	616	Q92841
FSHGNSFHGTGGRGN	CFAP69	461	A5D8W1
GDFTNHNGTGGKSIY	PPIE	201	Q9UNP9
SYQGSRNGYLGGHGF	PARD3	1261	Q8TEW0
QMHGTTGFYQGGNGL	EYA2	136	O00167
QHSSFGYGGLQGPAS	PITX1	291	P78337
GGGYSSYGNSDNTHG	XG	111	P55808
NPGGQLGGASAGAYH	FOXE1	341	O00358
ETNDTNGYSSGGGGH	NKX1-1	166	Q15270
NGYSSGGGGHSPSAD	NKX1-1	171	Q15270
GGRGSQNYHQGGQFE	FAM98A	481	Q8NCA5
SLNFTYGAPGAGNGS	NIPAL2	21	Q9H841
GGAGDSLSYHSGQKF	MFAP4	171	P55083
SNHYVGLAGTGAASG	SLC5A4	81	Q9NY91
GYNSIGHFCGGWAGN	MYCBP2	3271	O75592
AYGQGFGGGQAQDLS	PRR12	456	Q9ULL5
AAGGGYAHVNGWANG	SOX1	176	O00570
YAGGGGFVLSGATLH	B3GNT9	286	Q6UX72
AHNGGSAFGAAGYGG	PKP3	136	Q9Y446
ANSGGRSPNAYSGGH	RBMXL3	601	Q8N7X1
SGGHDSSGQSNCYGG	RBMXL3	651	Q8N7X1
GGHDSSSQSNRYGGG	RBMXL3	691	Q8N7X1
SGGRSPNAYSGGHNS	RBMXL3	791	Q8N7X1
SQYSFTGGSQGNHLG	STOX1	756	Q6ZVD7
GYSGVGNSSVSGHGI	RFX7	971	Q2KHR2
PQGSSFGNQYGSEGH	TCF20	121	Q9UGU0
GAFGEHGSQGTYSNT	MAP2	56	P11137
SGGHLYGFGAKSNGG	ZNF608	231	Q9ULD9
GAGAGASAGSNGSNY	PJA1	426	Q8NG27
GGTYLGHFENGLFNG	MORN4	36	Q8NDC4
GYSFTTSGGHSLGAG	KRT75	501	O95678
AGQGFSYSKSNGRGG	MYOZ1	101	Q9NP98
SQAGGSGSAGQYGSD	MYOZ1	116	Q9NP98