Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiontranscription coactivator activity

CITED2 DYRK1A CTBP2 DCAF6 TRRAP

2.00e-04303365GO:0003713
GeneOntologyMolecularFunctionhistone H3 kinase activity

DYRK1A RPS6KA4

2.06e-0412362GO:0140996
GeneOntologyBiologicalProcesspositive regulation of transcription by RNA polymerase II

MEPCE SOX17 CITED2 NKX2-3 GTF2A1 CTBP2 TNKS DCAF6 USF3 RPS6KA4 MLLT10 FOXJ3

2.29e-0613903612GO:0045944
DomainTF_fork_head_CS_2

FOXJ3 FOXG1

2.98e-0346332IPR030456
DomainTF_fork_head_CS_1

FOXJ3 FOXG1

3.11e-0347332IPR018122
DomainFORK_HEAD_3

FOXJ3 FOXG1

3.38e-0349332PS50039
DomainFH

FOXJ3 FOXG1

3.38e-0349332SM00339
DomainFORK_HEAD_1

FOXJ3 FOXG1

3.38e-0349332PS00657
DomainFORK_HEAD_2

FOXJ3 FOXG1

3.38e-0349332PS00658
DomainForkhead

FOXJ3 FOXG1

3.38e-0349332PF00250
DomainFork_head_dom

FOXJ3 FOXG1

3.38e-0349332IPR001766
DomainChannel_four-helix_dom

CACNA1D CATSPER1

4.55e-0357332IPR027359
Domain-

CACNA1D CATSPER1

4.55e-03573321.20.120.350
DomainKinase-like_dom

DYRK1A RPS6KA4 TRRAP NLK

1.47e-02542334IPR011009
DomainIon_trans_dom

CACNA1D CATSPER1

1.72e-02114332IPR005821
DomainIon_trans

CACNA1D CATSPER1

1.72e-02114332PF00520
PathwayWP_MESODERMAL_COMMITMENT_PATHWAY

SOX17 CTBP2 SCHIP1 ZNF281 NLK

6.29e-06153255M39546
PathwayREACTOME_SIGNALING_BY_WNT

SOX17 CTBP2 TNKS TRRAP NLK

5.41e-05239255MM14756
PathwayWP_ENDODERM_DIFFERENTIATION

SOX17 CTBP2 ZNF281 NLK

1.09e-04143254M39591
PathwayREACTOME_SIGNALING_BY_WNT

SOX17 CTBP2 TNKS TRRAP NLK

2.46e-04330255M7847
PathwayWP_NCRNAS_INVOLVED_IN_WNT_SIGNALING_IN_HEPATOCELLULAR_CARCINOMA

SOX17 CTBP2 NLK

5.06e-0489253M39563
PathwayWNT_SIGNALING

SOX17 CTBP2 NLK

5.06e-0489253M5493
PathwayWP_LNCRNA_IN_CANONICAL_WNT_SIGNALING_AND_COLORECTAL_CANCER

SOX17 CTBP2 NLK

6.71e-0498253M39731
PathwayWP_WNT_SIGNALING_PATHWAY

CTBP2 ANKRD6 NLK

9.38e-04110253MM15977
PathwayWP_WNT_SIGNALING_WP428

SOX17 CTBP2 NLK

1.01e-03113253M39669
PathwayREACTOME_SIGNALING_BY_WNT_IN_CANCER

CTBP2 TNKS

1.64e-0334252M27405
Pubmed

The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.

MEPCE CITED2 DYRK1A GTF2A1 TNKS SLC39A10 ZNF281 AMOT FOXG1 NLK

2.64e-071203361029180619
Pubmed

The protein interaction landscape of the human CMGC kinase group.

MEPCE DYRK1A CTBP2 RPS6KA4 ZNF281 UBAP2L NLK

6.23e-0669536723602568
Pubmed

Conditional Creation and Rescue of Nipbl-Deficiency in Mice Reveals Multiple Determinants of Risk for Congenital Heart Defects.

SOX17 CITED2 AMOT

7.10e-063636327606604
Pubmed

EZH2 and BCL6 Cooperate to Assemble CBX8-BCOR Complex to Repress Bivalent Promoters, Mediate Germinal Center Formation and Lymphomagenesis.

ZNF281 UBAP2L AMOT

1.31e-054436327505670
Pubmed

Human ISG15 conjugation targets both IFN-induced and constitutively expressed proteins functioning in diverse cellular pathways.

MEPCE DYRK1A ZNF281 UBAP2L

1.85e-0515236416009940
Pubmed

Homologs of genes expressed in Caenorhabditis elegans GABAergic neurons are also found in the developing mouse forebrain.

NKX2-3 FOXJ3 FOXG1

2.87e-055736321122108
Pubmed

Linking H3K79 trimethylation to Wnt signaling through a novel Dot1-containing complex (DotCom).

MLLT10 TRRAP

2.91e-05836220203130
Pubmed

The protein network surrounding the human telomere repeat binding factors TRF1, TRF2, and POT1.

GTF2A1 TNKS FOXJ3 ZNF281

5.10e-0519736420811636
Pubmed

Maintenance of the specification of the anterior definitive endoderm and forebrain depends on the axial mesendoderm: a study using HNF3beta/Foxa2 conditional mutants.

AMOT FOXG1

5.70e-051136211846474
Pubmed

A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.

CITED2 GTF2A1 MLLT10 FOXJ3 BIRC6 FOXG1

8.13e-0570936622988430
Pubmed

A Gata3-Mafb transcriptional network directs post-synaptic differentiation in synapses specialized for hearing.

CTBP2 FOXG1

9.41e-051436224327562
Pubmed

Roles of ErbB3-binding protein 1 (EBP1) in embryonic development and gene-silencing control.

SOX17 FOXG1

1.08e-041536231748268
Pubmed

Conditional mutations of beta-catenin and APC reveal roles for canonical Wnt signaling in lens differentiation.

SOX17 CTBP2 NLK

1.12e-049036319515997
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

CTBP2 DCAF6 USF3 TRRAP FOXJ3 UBAP2L NLK HPS3

1.15e-04148936828611215
Pubmed

Proteostasis is essential during cochlear development for neuron survival and hair cell polarity.

CTBP2 FOXG1

1.76e-041936231321879
Pubmed

ASPP2 maintains the integrity of mechanically stressed pseudostratified epithelia during morphogenesis.

SOX17 AMOT

1.76e-041936235177595
Pubmed

Embryo model completes gastrulation to neurulation and organogenesis.

SOX17 FOXG1

2.38e-042236236007540
Pubmed

The RNF146 and tankyrase pathway maintains the junctional Crumbs complex through regulation of angiomotin.

TNKS AMOT

2.38e-042236227521426
Pubmed

USP7 Regulates Cytokinesis through FBXO38 and KIF20B.

FBXO38 TRRAP ZNF281

2.38e-0411636330804394
Pubmed

A census of human transcription factors: function, expression and evolution.

SOX17 NKX2-3 USF3 FOXJ3 ZNF281 FOXG1

3.11e-0490836619274049
Pubmed

Human ATAC Is a GCN5/PCAF-containing acetylase complex with a novel NC2-like histone fold module that interacts with the TATA-binding protein.

TRRAP UBAP2L

3.60e-042736218838386
Pubmed

The pseudophosphatase STYX targets the F-box of FBXW7 and inhibits SCFFBXW7 function.

FBXO38 C2orf49

3.60e-042736228007894
Pubmed

Proteomic analysis and identification of cellular interactors of the giant ubiquitin ligase HERC2.

PRR14L BIRC6 HPS3

4.05e-0413936325476789
Pubmed

MYC Protein Interactome Profiling Reveals Functionally Distinct Regions that Cooperate to Drive Tumorigenesis.

GTF2A1 CTBP2 TRRAP ZNF281

4.08e-0433936430415952
Pubmed

Correct patterning of the primitive streak requires the anterior visceral endoderm.

SOX17 FOXG1

4.45e-043036221445260
Pubmed

DNA-binding specificities of human transcription factors.

FOXJ3 FOXG1

4.75e-043136223332764
Pubmed

The Eyes Absent family members EYA4 and EYA1 promote PLK1 activation and successful mitosis through tyrosine dephosphorylation.

GTF2A1 FOXJ3 AMOT

5.26e-0415236338360978
Pubmed

Genome-wide association studies in an isolated founder population from the Pacific Island of Kosrae.

HEMGN SCHIP1

5.72e-043436219197348
Pubmed

Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.

MEPCE DYRK1A GTF2A1 ADAMTS14 SLC39A10 UBAP2L CPEB4

6.25e-04145136730550785
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

DYRK1A SLC39A10 ANKRD6 FOXJ3 UBAP2L AMOT

7.91e-04108436611544199
Pubmed

Regulation of epidermal differentiation through KDF1-mediated deubiquitination of IKKα.

MEPCE ZNF281 AMOT

8.86e-0418236332239614
Pubmed

The Evf2 Ultraconserved Enhancer lncRNA Functionally and Spatially Organizes Megabase Distant Genes in the Developing Forebrain.

PRR14L NLK

9.59e-044436230146317
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

TNKS USF3 MLLT10 FOXJ3

9.93e-0443036435044719
InteractionCNOT9 interactions

MEPCE DYRK1A CTBP2 BIRC6 UBAP2L CPEB4

2.61e-06231356int:CNOT9
InteractionEGLN3 interactions

CITED2 DYRK1A CTBP2 PRR14L SLC39A10 PIPSL ZNF281 BIRC6 UBAP2L AMOT CPEB4

7.40e-0612963511int:EGLN3
InteractionRNF4 interactions

MEPCE CITED2 DYRK1A GTF2A1 TNKS SLC39A10 ZNF281 BIRC6 AMOT FOXG1 NLK

1.67e-0514123511int:RNF4
InteractionCNOT3 interactions

DYRK1A TRRAP UBAP2L NLK CPEB4

2.75e-05207355int:CNOT3
InteractionRTRAF interactions

MEPCE DYRK1A C2orf49 UBAP2L CPEB4

3.84e-05222355int:RTRAF
InteractionCNOT11 interactions

DYRK1A UBAP2L NLK CPEB4

4.14e-05112354int:CNOT11
InteractionJCAD interactions

DYRK1A TRRAP AMOT

5.26e-0542353int:JCAD
InteractionTHAP11 interactions

HEMGN CTBP2 PIPSL TRRAP

5.79e-05122354int:THAP11
InteractionFOXO3 interactions

CTBP2 TRRAP FOXG1 NLK

6.17e-05124354int:FOXO3
InteractionAKAP7 interactions

MEPCE DCAF6 RPS6KA4

8.37e-0549353int:AKAP7
GeneFamilyForkhead boxes

FOXJ3 FOXG1

1.24e-0343222508
CoexpressionDUTERTRE_ESTRADIOL_RESPONSE_24HR_DN

CITED2 FBXO38 SCHIP1 SLC39A10 ZNF281 HPS3 CPEB4

4.80e-06504367M2157
ToppCellTCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-5|TCGA-Ovary / Sample_Type by Project: Shred V9

MEPCE DCAF6 USF3 FOXJ3 UBAP2L

2.21e-0716636532d2eaf8a5d03881bf74d680825af2d5110b082d
ToppCellSmart-seq2-blood_(Smart-seq2)-hematologic-hematopoietic_progenitor-hematopoietic_stem_cell|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

NKX2-3 HEMGN SELENOP SCHIP1

6.27e-06149364e99b7cd3728ce76b365526734c2e7f845b2e62c8
ToppCellSmart-seq2-blood_(Smart-seq2)-hematologic-hematopoietic_progenitor|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

NKX2-3 HEMGN SELENOP SCHIP1

6.27e-061493646a28dd4530ed411747fdfe743db138a1b5547ed7
ToppCellBAL-Severe-cDC_3|Severe / Compartment, Disease Groups and Clusters

CITED2 USF3 SLC39A10 AMOT

1.24e-05177364939487a05311b66edfc3f44a7955fbf25266d6bf
ToppCellPBMC-Mild-Hematopoietic-HSPC|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

NKX2-3 HEMGN SELENOP SCHIP1

1.29e-051793642f690f933bf6b99abeb31766e0b22bdbe36c1ba0
ToppCellPBMC-Mild-Hematopoietic-HSPC-HSPC-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

NKX2-3 HEMGN SELENOP SCHIP1

1.29e-051793644bb2debfc9e9f258cd38e797ef160bd440aad6af
ToppCellPBMC-Mild-Hematopoietic-HSPC-HSPC|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

NKX2-3 HEMGN SELENOP SCHIP1

1.29e-051793643e2c937369b8190fd5d5a31689d029e6e89fb5e2
ToppCellPBMC-Mild-Hematopoietic-HSPC-HSPC|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

NKX2-3 HEMGN SELENOP SCHIP1

1.35e-0518136454a19cf6a3b752e2391feb8b316bebee0e602d17
ToppCellPBMC-Mild-Hematopoietic-HSPC|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

NKX2-3 HEMGN SELENOP SCHIP1

1.35e-051813645b84625b1d3737708001b64f6da9360330d39a27
ToppCellPBMC-Mild-Hematopoietic-HSPC-HSPC-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

NKX2-3 HEMGN SELENOP SCHIP1

1.35e-05181364e7f7b519c2a01c15f26df11ec9b434c0d1630c7a
ToppCellnormal-na-Hematopoietic-progenitor_cell|normal / PBMC cell types (v2) per disease, treatment status, and sex

NKX2-3 HEMGN SELENOP SCHIP1

1.57e-05188364013162466a3334b6967c0cb670c8577d809b1396
ToppCellnormal-na-Hematopoietic-progenitor_cell-female|normal / PBMC cell types (v2) per disease, treatment status, and sex

NKX2-3 HEMGN SELENOP SCHIP1

1.57e-05188364be25371e6459504b5f0c9ece3a0fe8f80c7824ca
ToppCellLPS-IL1RA-Myeloid-Monocytes,_Macrophages-Erythroid|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CITED2 HEMGN CATSPER1

2.12e-041443637c471e332f87d60f4dbed01f3e66bf39995218d0
ToppCell10x_3'_v3-blood_(10x_3'_v3)-myeloid-myeloid_dendritic-CD141-positive_myeloid_dendritic_cell|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

NKX2-3 SELENOP SCHIP1

2.79e-041583634f3ea658e032555c2098d016475381c8d1071699
ToppCellwk_20-22-Hematologic-Myeloid-HSC/ELP|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

NKX2-3 HEMGN CCER2

3.11e-041643633c07d8f53511f269540bf032738a4ada35650b18
ToppCellwk_15-18-Hematologic-Meg-ery-HMOX1+_primitive_erythroblast|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

CITED2 HEMGN CPEB4

3.16e-04165363a040d18e4ba6da266440ad0b79990918770bfa7d
ToppCellfacs-Spleen-nan-18m-Hematologic-proerythroblast|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NKX2-3 HEMGN SCHIP1

3.22e-041663638d535fab019356894b4dad3fbdbc4d2ad3e16082
ToppCellfacs-Spleen-nan-18m-Hematologic-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NKX2-3 HEMGN SCHIP1

3.22e-04166363f56b1c0d6cb5353a16a2598bda905287f16d2c39
ToppCellfacs-Spleen-nan-18m-Hematologic|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NKX2-3 HEMGN SCHIP1

3.22e-04166363a5074c96c6561273029aceb93402a7e038140f50
ToppCellHealthy_donor-HSPC|World / disease group, cell group and cell class (v2)

HEMGN SELENOP SCHIP1

3.28e-0416736370630ebdfee8171d625811844f8a7c94736d101e
ToppCellfacs-Skin-Anagen-24m-Epithelial-bulge_keratinocyte|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CITED2 CTBP2 MARCHF11

3.28e-0416736378909f685ccd1321064eb0887caf9263e0e54879
ToppCellE17.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CITED2 CACNA1D PRR14L

3.45e-041703637fa022471e14ac8a3bc147c793368a4d56a8e591
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Myeloid-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DYRK1A FBXO38 CPEB4

3.45e-04170363f3d5678669dcaed1836014cea543758b7ccc6b46
ToppCellHealthy_donor-HSPC|Healthy_donor / disease group, cell group and cell class (v2)

HEMGN SELENOP SCHIP1

3.57e-04172363bc7549faadfc92c683c0e26bea380458706774b5
ToppCellfacs|World / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GTF2A1 PRR14L BIRC6

3.57e-04172363a2d0a64ebf09d219a07d6bbad1056bad6d46b9be
ToppCellsevere_COVID-19-HSPC|severe_COVID-19 / disease group, cell group and cell class (v2)

NKX2-3 SELENOP SCHIP1

3.70e-041743636d35bacf073537b272ff821e604c899fb9ce6a7c
ToppCellLPS-IL1RA-Hematopoietic_Meg-Ery-Erythroid|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HEMGN CATSPER1 CPEB4

3.76e-041753634d36da7399c62c170cb603957b35a35efb2c3fbe
ToppCellLPS-IL1RA-Hematopoietic_Meg-Ery|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HEMGN CATSPER1 CPEB4

3.76e-041753632c39c1b112e873403ad2add8595cc256bf0b97a6
ToppCellfacs-Skin-Anagen-24m-Epithelial-outer_bulge|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CITED2 CTBP2 MARCHF11

3.76e-041753635552ff1e13f931c8cd7780726c90b5609497a648
ToppCellP15-Endothelial-lymphatic_endothelial_cell-endothelial_cell_of_lymphatic_vessel|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SELENOP ANKRD6 MARCHF11

3.76e-0417536384d252f3e432231687613299bbea14978bb4b06b
ToppCellLPS-IL1RA-Hematopoietic_Meg-Ery-Erythroid-Erythroid|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HEMGN CATSPER1 CPEB4

3.76e-04175363e4c9b3c6bde390a3892b112b673f93e118220eb9
ToppCellP15-Endothelial-lymphatic_endothelial_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SELENOP ANKRD6 MARCHF11

3.76e-04175363a00c6fa9b33640710dd05a3799031147196f0986
ToppCell10x5'v1-week_17-19-Myeloid_macrophage-stroma-erythroid_macrophage|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

HEMGN SELENOP ADAMTS14

3.88e-04177363b647667da62a91dbe3890820142626e26aa779d2
ToppCellsevere_COVID-19-HSPC|World / disease group, cell group and cell class (v2)

NKX2-3 SELENOP SCHIP1

3.88e-04177363289f6aed6f054b04b01659434d8c8b467d1bf5dd
ToppCellLPS-IL1RA+antiTNF-Hematopoietic_Meg-Ery|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HEMGN CATSPER1 CPEB4

4.01e-041793637329b45376a9e9a4fe34d4aa0b33af6dda0a8e3b
ToppCellCOVID-19_Mild-Hematopoietic_SC-HSPC|COVID-19_Mild / Disease group, lineage and cell class

HEMGN SELENOP SCHIP1

4.01e-0417936319fcf48f5e02e4cb2b328efb4502f337e1282f72
ToppCellLPS-IL1RA+antiTNF-Hematopoietic_Meg-Ery-Erythroid|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HEMGN CATSPER1 CPEB4

4.01e-041793636e4740f99f66d3e9348fa5057cf1030454819aa8
ToppCellCOVID-19_Mild-Hematopoietic_SC|COVID-19_Mild / Disease group, lineage and cell class

HEMGN SELENOP SCHIP1

4.01e-0417936350a073166e34bcfa52a62c4dafb3aef724e0fa8e
ToppCellLPS-IL1RA+antiTNF-Hematopoietic_Meg-Ery-Erythroid-Erythroid|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HEMGN CATSPER1 CPEB4

4.01e-04179363ee60ac43fb62c09967a26bbcf9306ac5ea2bdc1e
ToppCellMatrixFB-Fibroblast-A|MatrixFB / shred on cell class and cell subclass (v4)

CITED2 CACNA1D SELENOP

4.08e-04180363adc64ad6033af705dd7b9163a83e20ef5c59f6eb
ToppCellPBMC-Control-Hematopoietic-HSPC-HSPC-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

HEMGN SELENOP SCHIP1

4.21e-041823636497eeafb2b137e70261ec0314782831892a940d
ToppCellControl-Hematopoietic_SC-HSPC|Control / Disease group, lineage and cell class

HEMGN SELENOP SCHIP1

4.21e-0418236314e347c0e6444410f1948851407bb18c706569f4
ToppCellControl-Hematopoietic_SC|Control / Disease group, lineage and cell class

HEMGN SELENOP SCHIP1

4.21e-0418236343243c6bae2ac7fa3fd1f193a17f61ee4d938ea9
ToppCellPBMC-Control-Hematopoietic-HSPC-HSPC|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

HEMGN SELENOP SCHIP1

4.21e-04182363d0ebf2f0d5370458ab81485a0017c311077133d5
ToppCellPBMC-Control-Hematopoietic-HSPC|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

HEMGN SELENOP SCHIP1

4.21e-04182363918286422b3eab32d962b49aa07b1b9512e51d9d
ToppCellPBMC-Control-Hematopoietic-HSPC|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

HEMGN SELENOP SCHIP1

4.21e-04182363bd1626261803324084fafca2f6665b50854e7fae
ToppCellPBMC-Control-Hematopoietic-HSPC-HSPC-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

HEMGN SELENOP SCHIP1

4.21e-041823632a6d1246bfb5899a0861c7f2f8fb9b43b0df8acc
ToppCellPBMC-Control-Hematopoietic-HSPC-HSPC|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

HEMGN SELENOP SCHIP1

4.21e-041823630d9b8c900da8cbae9cde72aecd4026b1ac2bbd67
ToppCell10x_3'_v2v3-Neoplastic-Stem-like-NPC-like-NPC-like_neural-A|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SCHIP1 CCER2 FOXG1

4.28e-04183363af14da45267261e775dd6dab7a4c359b181e46f1
ToppCellfacs-Lung-Endomucin-3m-Endothelial-Capillary_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX17 SELENOP DCAF6

4.28e-041833631e51aeaa8fc9383b424cce128a890e07cb6025f3
ToppCellCOVID-19_Moderate-HSPC|World / disease group, cell group and cell class

HEMGN SELENOP SCHIP1

4.35e-04184363ccc93babe1fcdeb66b78e1d8414357877a7c45bd
ToppCellsystemic_lupus_erythematosus-managed-Hematopoietic-progenitor_cell-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

SELENOP SCHIP1 CCER2

4.42e-041853632c07991e0907ded67e21ab2e66be21695842ed01
ToppCellCOVID-19_Moderate-HSPC|COVID-19_Moderate / disease group, cell group and cell class

HEMGN SELENOP SCHIP1

4.42e-04185363cacc6ab5f26f6c803894567fb838ea06eaa7efe5
ToppCellLPS_only-Hematopoietic_Meg-Ery-Erythroid|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HEMGN CATSPER1 CPEB4

4.49e-04186363affc246a1091e44dc85a5e237c778a7541d5a2b4
ToppCellsystemic_lupus_erythematosus-flare-Hematopoietic-progenitor_cell|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

SELENOP SCHIP1 ADAMTS14

4.49e-04186363ffd4510b4435d9bf94c2ef14c629f73ab78c5d93
ToppCellLPS_only-Hematopoietic_Meg-Ery|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HEMGN CATSPER1 CPEB4

4.49e-0418636340d1e15402fdfb3b5ae850a2070cd4b68fda3159
ToppCellLPS_only-Hematopoietic_Meg-Ery-Erythroid-Erythroid|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HEMGN CATSPER1 CPEB4

4.49e-04186363e5014443e9d6e25943308483e20d48b776ae5373
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1|TCGA-Pancreas / Sample_Type by Project: Shred V9

FBXO38 GTF2A1 BIRC6

4.49e-0418636303db813598b67b1e08f759758a1c2023396921fa
ToppCellsystemic_lupus_erythematosus-flare-Hematopoietic-progenitor_cell-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

SELENOP SCHIP1 ADAMTS14

4.63e-04188363c613c6c7b6de8ed514253c9f9b8622c56fcc1452
ToppCellhematopoetic_progenitors-CD34+_HSC|World / Lineage and Cell class

NKX2-3 HEMGN SELENOP

4.70e-0418936351ff31c9cf5eff98ad01c0455dc4ae4908713575
ToppCellCOVID-19_Severe-HSPC|World / disease group, cell group and cell class

NKX2-3 HEMGN SELENOP

4.70e-04189363555c0b13f1508b9e3712b36d77144e73e828bc76
ToppCellHealthy-HSPC|Healthy / disease group, cell group and cell class

HEMGN SELENOP SCHIP1

4.70e-04189363214b225effc40ca1b83dd8052f2a7b80b65d4938
ToppCell(5)_Fibroblasts-(5)_Fibroblast-C_(Myofibroblast)|(5)_Fibroblasts / Lung cell shreds - cell class (v4) and cell subclass (v4)

CITED2 CACNA1D SELENOP

4.78e-0419036371e112dfb8c3190fe0286b45a046ea789eb6a8db
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro1_(4)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

CITED2 CACNA1D SELENOP

4.78e-041903637986586b7c82e91c71102cc8c4d7a689ae63ab4d
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro1_(4)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

CITED2 CACNA1D SELENOP

4.85e-04191363fa380a8752de158974b2ae5e741573439719cc0d
ToppCellILEUM-non-inflamed|ILEUM / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

CITED2 NKX2-3 SELENOP

4.85e-04191363c4a78ef7b87ffadbb1b9b69cbfa7c164ca456f9a
ToppCellhematopoetic_progenitors-CD34+_MEP_2|hematopoetic_progenitors / Lineage and Cell class

CITED2 CATSPER1 NLK

4.85e-041913633b061dbc10918be7cbbd4453311d2c1ebf18c6b2
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Endothelial-endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX17 SELENOP SLC39A10

4.92e-04192363042391162df2e3d0027688dd14163c4c6821afe0
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Endothelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX17 SELENOP SLC39A10

4.92e-0419236371b0bfee0461ff64cef35881db3959c517e9731b
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Endothelial-Endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX17 SELENOP SLC39A10

4.92e-041923639d53b42cdb537b30233cdfdc08052c8b13a1113f
ToppCellInfluenza_Severe-RBC|Influenza_Severe / Disease group and Cell class

HEMGN SELENOP CPEB4

4.92e-04192363f19b6da3fd98da1a76d2570137a8f73a3850ebcb
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DCAF6 SLC39A10 NLK

4.92e-041923635c7e8b80b44d9ce55c797cdf8267ac5382e26cac
ToppCell10x_3'_v3-bone_marrow_(10x_3'_v3)-hematologic-hematopoietic_progenitor-hematopoietic_stem_cell|bone_marrow_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

NKX2-3 HEMGN SCHIP1

4.92e-0419236361677831b096b36f6325e9cb047483dd72aa71c2
ToppCellTCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6|TCGA-Prostate / Sample_Type by Project: Shred V9

USF3 ZNF281 BIRC6

5.00e-04193363abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

CITED2 CACNA1D SELENOP

5.08e-04194363a3e5a15cf6c1361207f661ee15eb634f77daf1cb
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro1_(4)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

CITED2 CACNA1D SELENOP

5.08e-0419436371d3c7448b1734de54187f902f65649f9283bd4c
ToppCellMild-NK|Mild / Disease group and Cell class

CTBP2 CATSPER1 SLC39A10

5.15e-04195363be88a7507cd6a0a9dfe424312d9365039eef7b74
ToppCell367C-Fibroblasts-Fibroblast-C_(Myofibroblast)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

CITED2 CACNA1D SELENOP

5.23e-041963636730743cf088c419ccc2d28765769fc09d3ba6a7
ToppCell367C-Fibroblasts-Fibroblast-C_(Myofibroblast)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

CITED2 CACNA1D SELENOP

5.23e-0419636321dab89f3699037138a9c7a0e4dc98739a9fad9c
ToppCell10x5'v1-week_12-13-Hematopoietic-erythroid-mid_erythroid|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

HEMGN DCAF6 CPEB4

5.31e-04197363d8f99a9f2367c8bc9308b0c64d0226875262927a
ToppCellILEUM-inflamed-(7)_Endothelial_cell-(7)_CD36+_endothelial_cells|(7)_Endothelial_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

SOX17 NKX2-3 SELENOP

5.31e-0419736366339b5aae3952f5c484c9dcb0cfb4fbd828d4cb
ToppCellVE-NK|VE / Condition, Cell_class and T cell subcluster

CTBP2 CATSPER1 SLC39A10

5.31e-04197363cae6ff8763501e7a5897b50188ac2640d65a47c0
ToppCellVE-NK-|VE / Condition, Cell_class and T cell subcluster

CTBP2 CATSPER1 SLC39A10

5.31e-04197363ee89b8521fb4faaed9e4d39f7171e45eccf38b00
ToppCellfacs-Lung-18m|Lung / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SOX17 SELENOP CTBP2

5.46e-04199363c11e0044d3cc37f6bb26df033ad4448b419addfc
ToppCellTracheal-NucSeq|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations

DYRK1A TNKS BIRC6

5.46e-0419936394b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCellLPS_anti-TNF-Hematopoietic_Erythro-Megakary-Erythro-Mega|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

HEMGN ANKRD6 CPEB4

5.46e-04199363284ee9632413f6404fc0b0c7c393ad813db834f2
ToppCellTCGA-Stomach-Primary_Tumor|TCGA-Stomach / Sample_Type by Project: Shred V9

SLC39A10 ZNF281 UBAP2L

5.46e-0419936338f1f612b29feb868322999ceeda78e52447ec4f
ToppCellLPS_anti-TNF-Hematopoietic_Erythro-Megakary|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

HEMGN ANKRD6 CPEB4

5.46e-041993636c174dbcc25b980f10a3d1dfe39e613acac73bb6
ToppCellTCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma|TCGA-Stomach / Sample_Type by Project: Shred V9

SLC39A10 ZNF281 UBAP2L

5.46e-04199363b10698aee2e6c17bc559eb4f723024141f914b90
ToppCell(2)_B_cell-(21)_B_cell_IgG_Plasma|(2)_B_cell / shred on Cell_type and subtype

CITED2 GTF2A1 CPEB4

5.55e-042003632831060d52b210f8927527810611735a99b61999
DiseaseMicrocephaly

DYRK1A TRRAP FOXG1

6.95e-0567353C0025958
Diseaseprion disease

ADAMTS14 CPEB4

2.31e-0419352EFO_0004720
Diseaseserum IgG glycosylation measurement

CITED2 DYRK1A GTF2A1 USF3 MARCHF11

3.59e-04523355EFO_0005193
Diseasesmoking status measurement

CACNA1D RPS6KA4 MLLT10 C2orf49 BIRC6 UBAP2L CPEB4

3.65e-041160357EFO_0006527
Diseasepallidum volume

TNKS BIRC6

4.03e-0425352EFO_0006933
Diseaseandrosterone sulfate measurement

MEPCE BIRC6

7.05e-0433352EFO_0021117
DiseaseAdenoma

CACNA1D SELENOP

8.40e-0436352C0001430
DiseaseAdenoma, Microcystic

CACNA1D SELENOP

8.40e-0436352C0205648
DiseaseAdenoma, Monomorphic

CACNA1D SELENOP

8.40e-0436352C0205649
DiseaseAdenoma, Basal Cell

CACNA1D SELENOP

8.40e-0436352C0205646
DiseaseFollicular adenoma

CACNA1D SELENOP

8.40e-0436352C0205647
DiseasePapillary adenoma

CACNA1D SELENOP

8.40e-0436352C0205650
DiseaseAdenoma, Trabecular

CACNA1D SELENOP

8.40e-0436352C0205651
Diseasecomplement factor H measurement

FBXO38 NLK

1.09e-0341352EFO_0008097
Diseaseexecutive function measurement, unipolar depression, cognitive function measurement

NKX2-3 DCAF6

1.68e-0351352EFO_0003761, EFO_0008354, EFO_0009332
Diseasenervous system disorder

SELENOP FOXG1

1.81e-0353352C0027765
Diseasemean reticulocyte volume

CITED2 DYRK1A FBXO38 TRRAP HPS3

2.38e-03799355EFO_0010701
Diseaseattention deficit hyperactivity disorder, substance abuse, antisocial behaviour measurement

CACNA1D C2orf49 BIRC6 UBAP2L CPEB4

2.41e-03801355EFO_0003888, EFO_0007052, MONDO_0002491
DiseaseBenign Neoplasm

CITED2 BIRC6

2.96e-0368352C0086692
DiseaseNeoplasms

CITED2 BIRC6

2.96e-0368352C0027651
Diseaseasthma, endometriosis

TNKS MLLT10

3.50e-0374352EFO_0001065, MONDO_0004979
DiseaseEpilepsy, Cryptogenic

DYRK1A FOXG1

4.28e-0382352C0086237
DiseaseAwakening Epilepsy

DYRK1A FOXG1

4.28e-0382352C0751111
DiseaseAura

DYRK1A FOXG1

4.28e-0382352C0236018

Protein segments in the cluster

PeptideGeneStartEntry
HNNNDAKQNHDLTHR

C2orf49

166

Q9BVC5
QQQQHHHHHHHQQQQ

AMOT

381

Q4VCS5
HHHHHHQQQQQQQPQ

AMOT

386

Q4VCS5
RRHPQHLHQQHHGDA

BIRC6

1056

Q9NR09
GLQHDESQHHQVPHR

CATSPER1

201

Q8NEC5
LHCNLNEHNHHLIND

CTBP2

241

P56545
SGHHTHHQSDNNNEK

DCAF6

451

Q58WW2
VAPQQNALHHHHGNS

DYRK1A

591

Q13627
SQQRQDPSHAEHHDH

ADAMTS14

341

Q8WXS8
DQQPGHQKNLHAHNH

ANKRD6

356

Q9Y2G4
KRHRHRGQHHQQQQA

MEPCE

261

Q7L2J0
HTSHNKNDHLQEEDH

MFI

111

Q8NCR3
EAVQNDNHHASHGHH

FOXG1

26

P55316
QQHKLKTHQHHNPNE

FAM214A

241

Q32MH5
QSHPNVVNLHEVHHD

RPS6KA4

461

O75676
VKAHHHQHSHHPQQQ

NLK

121

Q9UBE8
DQSHLKHHQTPDPHQ

HEMGN

6

Q9BXL5
KHHQTPDPHQEENHS

HEMGN

11

Q9BXL5
HVAHLALKHRQGNNH

PIPSL

576

A2A3N6
AQNNNANIHDNNHHH

FBXO38

501

Q6PIJ6
ANIHDNNHHHPDDSD

FBXO38

506

Q6PIJ6
HHHHHQPEAEPRQEK

CCER2

216

I3L3R5
HQHIQHHPNHQHQTL

FOXJ3

421

Q9UPW0
DQRAGHQHQHHQPIC

MARCHF11

156

A6NNE9
HPHFQHHHSQHQQQR

CPEB4

236

Q17RY0
HHHSQHQQQRRSPAS

CPEB4

241

Q17RY0
AVQEGKHFHSHNHQH

SLC39A10

116

Q9ULF5
HNHQHSHNHLNSENQ

SLC39A10

126

Q9ULF5
EQQHQHFHGAHLQAD

NKX2-3

21

Q8TAU0
VCHNHHNHNSIGKQV

CACNA1D

1736

Q01668
CEADDNHQQLHGHHN

PRR14L

306

Q5THK1
FQMQPQHQHQHQHQH

SOX17

311

Q9H6I2
KNGERVHHHPHKTNN

HPS3

216

Q969F9
NLHQHDPQDLRHNGN

SCHIP1

151

P0DPB3
HHKHKGQHRQGHPEN

SELENOP

246

P49908
MQHHHQQHHQPELQQ

MLLT10

996

P55197
PHHHQQQQPQHAFNA

CITED2

36

Q99967
QQQHQPQQQQHHHHH

GTF2A1

71

P52655
QPHSQILHHHLQQDG

UBAP2L

1041

Q14157
RSQHHHHHHQQQLQP

TNKS

6

O95271
KPADPEEQQSHHHHH

ZNF281

131

Q9Y2X9
HQHVQQQPAQHHRDV

ZNF281

181

Q9Y2X9
RNHHNHPQNHLNQDI

USF3

1586

Q68DE3
EHAPHHIHDNNKNRN

TRRAP

1841

Q9Y4A5