Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionryanodine-sensitive calcium-release channel activity

RYR1 RYR2 RYR3

1.59e-0641483GO:0005219
GeneOntologyMolecularFunctionATP hydrolysis activity

VPS4A SMCHD1 ABCB5 WRN SRP54 ABCC6 EIF4A1 EIF4A2 AFG3L2 ABCB11 KIF14 CHD6 POLQ ABCG8

5.33e-0644114814GO:0016887
GeneOntologyMolecularFunctioncalcium-induced calcium release activity

RYR1 RYR2 RYR3

7.85e-0661483GO:0048763
GeneOntologyMolecularFunctioncalcium ion binding

CAPN14 SWAP70 FSTL5 PCLO FKBP9 PKD1L2 ITIH4 RYR1 RYR2 RYR3 CELSR1 THBS4 SLC25A12 UMODL1 C1R CDH10 CDH12

4.14e-0574914817GO:0005509
GeneOntologyMolecularFunctionATP-dependent activity

DNHD1 VPS4A SMCHD1 ABCB5 WRN SRP54 ABCC6 EIF4A1 EIF4A2 AFG3L2 ABCB11 KIF14 CHD6 POLQ ABCG8

5.30e-0561414815GO:0140657
GeneOntologyMolecularFunctiontRNA-4-demethylwyosine synthase activity

TYW1B TYW1

5.46e-0521482GO:0102521
GeneOntologyMolecularFunctionribonucleoside triphosphate phosphatase activity

RAB12 VPS4A SMCHD1 RNF112 ABCB5 WRN SRP54 ABCC6 EIF4A1 EIF4A2 AFG3L2 RAB2B ABCB11 KIF14 CHD6 POLQ ABCG8

6.32e-0577514817GO:0017111
GeneOntologyMolecularFunctionxenobiotic transmembrane transporter activity

ABCB5 ABCC6 SLC22A6 ABCB11

1.13e-04341484GO:0042910
GeneOntologyMolecularFunctionC-rich single-stranded DNA binding

PCBP3 PCBP2

1.63e-0431482GO:1990829
GeneOntologyMolecularFunctionpyrophosphatase activity

RAB12 VPS4A SMCHD1 RNF112 ABCB5 WRN SRP54 ABCC6 EIF4A1 EIF4A2 AFG3L2 RAB2B ABCB11 KIF14 CHD6 POLQ ABCG8

1.65e-0483914817GO:0016462
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides

RAB12 VPS4A SMCHD1 RNF112 ABCB5 WRN SRP54 ABCC6 EIF4A1 EIF4A2 AFG3L2 RAB2B ABCB11 KIF14 CHD6 POLQ ABCG8

1.67e-0484014817GO:0016817
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

RAB12 VPS4A SMCHD1 RNF112 ABCB5 WRN SRP54 ABCC6 EIF4A1 EIF4A2 AFG3L2 RAB2B ABCB11 KIF14 CHD6 POLQ ABCG8

1.67e-0484014817GO:0016818
GeneOntologyMolecularFunctionABC-type xenobiotic transporter activity

ABCB5 ABCC6 ABCB11

1.70e-04151483GO:0008559
GeneOntologyMolecularFunctionintracellularly gated calcium channel activity

RYR1 RYR2 RYR3

3.00e-04181483GO:0015278
GeneOntologyMolecularFunctionABC-type transporter activity

ABCB5 ABCC6 ABCB11 ABCG8

4.74e-04491484GO:0140359
GeneOntologyMolecularFunctionoxo-acid-lyase activity

TYW1B TYW1

1.12e-0371482GO:0016833
GeneOntologyMolecularFunctionligand-gated calcium channel activity

RYR1 RYR2 RYR3

1.54e-03311483GO:0099604
GeneOntologyMolecularFunctioncalmodulin binding

IQGAP2 CAMK1 RYR1 RYR2 RYR3 SCN2A CDK5RAP2

1.66e-032301487GO:0005516
GeneOntologyBiologicalProcesscellular response to alkaloid

CASP7 SLC1A3 RYR1 RYR2 RYR3

8.94e-06401465GO:0071312
GeneOntologyCellularComponentplatelet dense granule lumen

ITIH3 ITIH4 FAM3C

1.15e-04141463GO:0031089
DomainRyanodine_rcpt

RYR1 RYR2 RYR3

4.78e-0731473IPR003032
DomainRyanrecept_TM4-6

RYR1 RYR2 RYR3

4.78e-0731473IPR009460
DomainRyR

RYR1 RYR2 RYR3

4.78e-0731473PF02026
DomainRR_TM4-6

RYR1 RYR2 RYR3

4.78e-0731473PF06459
DomainRyan_recept

RYR1 RYR2 RYR3

4.78e-0731473IPR013333
DomainRIH_assoc-dom

RYR1 RYR2 RYR3

9.39e-0661473IPR013662
DomainIns145_P3_rec

RYR1 RYR2 RYR3

9.39e-0661473PF08709
DomainRIH_assoc

RYR1 RYR2 RYR3

9.39e-0661473PF08454
DomainRIH_dom

RYR1 RYR2 RYR3

9.39e-0661473IPR000699
DomainIns145_P3_rcpt

RYR1 RYR2 RYR3

9.39e-0661473IPR014821
DomainRyanodine_recept-rel

RYR1 RYR2 RYR3

9.39e-0661473IPR015925
Domain-

RYR1 RYR2 RYR3

9.39e-06614731.25.10.30
DomainRYDR_ITPR

RYR1 RYR2 RYR3

9.39e-0661473PF01365
DomainMIR

RYR1 RYR2 RYR3

5.50e-05101473PF02815
DomainMIR_motif

RYR1 RYR2 RYR3

5.50e-05101473IPR016093
DomainMIR

RYR1 RYR2 RYR3

5.50e-05101473PS50919
DomainMIR

RYR1 RYR2 RYR3

5.50e-05101473SM00472
DomainEIF4A1/2

EIF4A1 EIF4A2

6.15e-0521472IPR031258
DomaintRNA_wybutosine-synth

TYW1B TYW1

6.15e-0521472IPR013917
DomainWyosine_form

TYW1B TYW1

6.15e-0521472PF08608
Domain-

RAB12 DNHD1 VPS4A RNF112 ABCB5 WRN SRP54 ABCC6 SBNO1 EIF4A1 EIF4A2 AFG3L2 RAB2B ABCB11 CHD6 POLQ ABCG8

8.19e-05746147173.40.50.300
DomainP-loop_NTPase

RAB12 DNHD1 VPS4A RNF112 ABCB5 WRN SRP54 ABCC6 SBNO1 EIF4A1 EIF4A2 AFG3L2 RAB2B ABCB11 KIF14 CHD6 POLQ ABCG8

1.23e-0484814718IPR027417
DomainCH

IQGAP2 SPTBN5 TAGLN2 UTRN ARHGEF6

1.59e-04651475SM00033
Domain-

PPM1A PPM1B

1.84e-04314721.10.10.430
DomainPP2C_C

PPM1A PPM1B

1.84e-0431472PF07830
DomainPP2C_C

PPM1A PPM1B

1.84e-0431472IPR012911
DomainCH

IQGAP2 SPTBN5 TAGLN2 UTRN ARHGEF6

2.26e-04701475PF00307
Domain-

IQGAP2 SPTBN5 TAGLN2 UTRN ARHGEF6

2.42e-047114751.10.418.10
DomainCH

IQGAP2 SPTBN5 TAGLN2 UTRN ARHGEF6

2.76e-04731475PS50021
DomainCH-domain

IQGAP2 SPTBN5 TAGLN2 UTRN ARHGEF6

3.13e-04751475IPR001715
DomainABC_transporter_CS

ABCB5 ABCC6 ABCB11 ABCG8

3.27e-04421474IPR017871
DomainEF-hand-dom_pair

CAPN14 SWAP70 FSTL5 FKBP9 RYR1 RYR2 RYR3 SLC25A12 UTRN

4.57e-042871479IPR011992
DomainEF_hand_dom

CAPN14 SWAP70 FSTL5 FKBP9 RYR1 RYR2 RYR3 SLC25A12

5.09e-042321478IPR002048
DomainABC_tran

ABCB5 ABCC6 ABCB11 ABCG8

5.48e-04481474PF00005
DomainABC_TRANSPORTER_2

ABCB5 ABCC6 ABCB11 ABCG8

5.48e-04481474PS50893
DomainABC_TRANSPORTER_1

ABCB5 ABCC6 ABCB11 ABCG8

5.93e-04491474PS00211
DomainABC_transporter-like

ABCB5 ABCC6 ABCB11 ABCG8

6.40e-04501474IPR003439
DomainABC_membrane

ABCB5 ABCC6 ABCB11

8.56e-04241473PF00664
DomainITI_HC_C

ITIH3 ITIH4

9.04e-0461472IPR010600
DomainITI_HC_C

ITIH3 ITIH4

9.04e-0461472PF06668
DomainAAA

VPS4A ABCB5 SRP54 ABCC6 AFG3L2 ABCB11

9.82e-041441476SM00382
DomainAAA+_ATPase

VPS4A ABCB5 SRP54 ABCC6 AFG3L2 ABCB11

9.82e-041441476IPR003593
Domain-

CAPN14 FSTL5 FKBP9 RYR1 RYR2 RYR3 SLC25A12 UTRN

1.10e-0326114781.10.238.10
DomainPTPc_motif

MTMR8 PTPN23 CDC14A PTPN2

1.20e-03591474SM00404
DomainTyr_Pase_cat

MTMR8 PTPN23 CDC14A PTPN2

1.20e-03591474IPR003595
DomainABC_TM1F

ABCB5 ABCC6 ABCB11

1.35e-03281473PS50929
DomainABC1_TM_dom

ABCB5 ABCC6 ABCB11

1.35e-03281473IPR011527
DomainHelicase_C

WRN EIF4A1 EIF4A2 CHD6 POLQ

1.58e-031071475PF00271
DomainHELICc

WRN EIF4A1 EIF4A2 CHD6 POLQ

1.58e-031071475SM00490
DomainPH

ARHGAP42 SWAP70 ARHGAP10 PSD3 SPTBN5 IQSEC1 ROCK1 ARHGEF6

1.63e-032781478SM00233
DomainHelicase_C

WRN EIF4A1 EIF4A2 CHD6 POLQ

1.64e-031081475IPR001650
DomainFlavodoxin/NO_synth

TYW1B TYW1

1.67e-0381472IPR008254
DomainCullin_neddylation_domain

CUL7 CUL5

1.67e-0381472IPR019559
DomainFlavdoxin-like

TYW1B TYW1

1.67e-0381472IPR001094
DomainCullin_Nedd8

CUL7 CUL5

1.67e-0381472PF10557
DomainVIT

ITIH3 ITIH4

1.67e-0381472PF08487
DomainFLAVODOXIN_LIKE

TYW1B TYW1

1.67e-0381472PS50902
DomainCullin_Nedd8

CUL7 CUL5

1.67e-0381472SM00884
DomainVIT

ITIH3 ITIH4

1.67e-0381472SM00609
DomainFlavodoxin_1

TYW1B TYW1

1.67e-0381472PF00258
DomainPH_DOMAIN

ARHGAP42 SWAP70 ARHGAP10 PSD3 SPTBN5 IQSEC1 ROCK1 ARHGEF6

1.67e-032791478PS50003
DomainPH_domain

ARHGAP42 SWAP70 ARHGAP10 PSD3 SPTBN5 IQSEC1 ROCK1 ARHGEF6

1.71e-032801478IPR001849
DomainHELICASE_CTER

WRN EIF4A1 EIF4A2 CHD6 POLQ

1.71e-031091475PS51194
DomainHELICASE_ATP_BIND_1

WRN EIF4A1 EIF4A2 CHD6 POLQ

1.71e-031091475PS51192
DomainDEXDc

WRN EIF4A1 EIF4A2 CHD6 POLQ

1.71e-031091475SM00487
DomainHelicase_ATP-bd

WRN EIF4A1 EIF4A2 CHD6 POLQ

1.78e-031101475IPR014001
DomainPH_dom-like

ARHGAP42 SWAP70 ARHGAP10 MTMR8 PSD3 SPTBN5 JAK2 IQSEC1 ROCK1 ARHGEF6

2.03e-0342614710IPR011993
DomainrSAM

TYW1B TYW1

2.14e-0391472IPR007197
DomainPH_dom-spectrin-type

PSD3 SPTBN5

2.14e-0391472IPR001605
DomainCullin_homology

CUL7 CUL5

2.14e-0391472IPR016158
DomainRadical_SAM

TYW1B TYW1

2.14e-0391472PF04055
DomainPH

ARHGAP42 SWAP70 ARHGAP10 PSD3 SPTBN5 ROCK1 ARHGEF6

2.27e-032291477PF00169
DomainTyr_Pase_AS

MTMR8 PTPN23 CDC14A PTPN2

2.63e-03731474IPR016130
DomainDEAD/DEAH_box_helicase_dom

WRN EIF4A1 EIF4A2 POLQ

2.63e-03731474IPR011545
DomainDEAD

WRN EIF4A1 EIF4A2 POLQ

2.63e-03731474PF00270
DomainCullin

CUL7 CUL5

2.66e-03101472PF00888
DomainVIT

ITIH3 ITIH4

2.66e-03101472PS51468
DomainVIT

ITIH3 ITIH4

2.66e-03101472IPR013694
Domain-

TYW1B TYW1

2.66e-031014723.40.50.360
DomainFlavoprotein-like_dom

TYW1B TYW1

2.66e-03101472IPR029039
DomainCULLIN_2

CUL7 CUL5

2.66e-03101472PS50069
DomainCullin_N

CUL7 CUL5

2.66e-03101472IPR001373
DomainCULLIN_1

CUL7 CUL5

2.66e-03101472PS01256
DomainSM22_calponin

TAGLN2 ARHGEF6

3.23e-03111472IPR003096
Domain-

ARHGAP42 SWAP70 ARHGAP10 MTMR8 PSD3 SPTBN5 IQSEC1 ROCK1 ARHGEF6

3.85e-0339114792.30.29.30
DomainWWE

HUWE1 PARP12

3.86e-03121472PF02825
DomainWWE-dom

HUWE1 PARP12

3.86e-03121472IPR004170
DomainWWE

HUWE1 PARP12

3.86e-03121472PS50918
DomainPP2C_BS

PPM1A PPM1B

3.86e-03121472IPR000222
DomainPTPase_domain

PTPN23 CDC14A PTPN2

4.09e-03411473IPR000242
DomainY_phosphatase

PTPN23 CDC14A PTPN2

4.09e-03411473PF00102
Domain-

TYW1B TYW1 PC

4.38e-034214733.20.20.70
DomainI-BAR_dom

ARHGAP42 ARHGAP10

4.53e-03131472IPR013606
DomainTYR_PHOSPHATASE_1

MTMR8 PTPN23 CDC14A PTPN2

4.75e-03861474PS00383
DomainAldolase_TIM

TYW1B TYW1 PC

5.00e-03441473IPR013785
DomainRho_GTPase_activation_prot

ARHGAP42 IQGAP2 ARHGAP10 ARHGAP4

5.15e-03881474IPR008936
DomainPP2C_SIG

PPM1A PPM1B

5.26e-03141472SM00331
DomainER_TARGET

FKBP9 UGGT2 POGLUT2

6.01e-03471473PS00014
Domain-

WRN POLQ PIWIL3

6.01e-034714733.30.420.10
DomainFH2

FMN2 DAAM2

6.04e-03151472PS51444
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

MIA3 PDPR ARHGAP10 SUN1 MTMR8 PSD3 PTPN23 HUWE1 CUL7 CCDC61 CDC14A PPM1A PPM1B PTPN2 AKAP9 LNPEP CRLF3 AFG3L2 MKI67 FMN2 KIF14 LRP6 CDK5RAP2 ROCK1 UQCRC2 PC UTRN PRRC2B

1.27e-1410491512827880917
Pubmed

Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.

SUMF2 MIA3 SWAP70 SMCHD1 USP24 FKBP9 SRP54 PTPN23 URB2 RPL23 NAA35 LNPEP MORF4L1 EIF4A1 EIF4A2 AFG3L2 MKI67 UGGT2 FAM3C TAGLN2 UQCRC2 POGLUT2 RIOK2 PCBP2 ALDH7A1 PRRC2B

7.40e-1112971512633545068
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

HNRNPDL MIA3 RAPGEF6 IQGAP2 SUN1 SRP54 PTPN23 HUWE1 THOC2 SLC1A3 TYW1B EIF4A2 ZBTB10 FMN2 CDK5RAP2 ROCK1 TYW1 POGLUT2 CPLANE1 UTRN ARHGEF6 PARP12

2.00e-0910841512211544199
Pubmed

Chromatin Remodeling BAF155 Subunit Regulates the Genesis of Basal Progenitors in Developing Cortex.

SLC1A3 FOCAD CELSR1 MKI67 CDH10 CDH12

1.49e-0838151630240734
Pubmed

BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.

HNRNPDL SMCHD1 WRN USP24 HUWE1 THOC2 ITIH4 SNRPGP15 RPL23 ORC2 SLC25A12 EIF4A1 EIF4A2 AFG3L2 MKI67 IQSEC1 CHD6 TAGLN2 UQCRC2 PC RIOK2 PCBP2

6.55e-0813181512230463901
Pubmed

Type 1 and type 3 ryanodine receptors are selectively involved in muscarinic antinociception in mice: an antisense study.

RYR1 RYR2 RYR3

8.02e-083151318403125
Pubmed

The ryanodine receptor/calcium channel genes are widely and differentially expressed in murine brain and peripheral tissues.

RYR1 RYR2 RYR3

8.02e-08315137876312
Pubmed

Bidirectional coupling between ryanodine receptors and Ca2+ release-activated Ca2+ (CRAC) channel machinery sustains store-operated Ca2+ entry in human T lymphocytes.

RYR1 RYR2 RYR3

8.02e-083151322948152
Pubmed

Developmental changes in expression of the three ryanodine receptor mRNAs in the mouse brain.

RYR1 RYR2 RYR3

8.02e-083151310788707
Pubmed

Ca(2+)-induced Ca2+ release in myocytes from dyspedic mice lacking the type-1 ryanodine receptor.

RYR1 RYR2 RYR3

8.02e-08315137621815
Pubmed

Molecular identification of the ryanodine receptor pore-forming segment.

RYR1 RYR2 RYR3

8.02e-083151310473538
Pubmed

Heterogeneous gene expression and functional activity of ryanodine receptors in resistance and conduit pulmonary as well as mesenteric artery smooth muscle cells.

RYR1 RYR2 RYR3

8.02e-083151318434746
Pubmed

SPRY domains in ryanodine receptors (Ca(2+)-release channels).

RYR1 RYR2 RYR3

8.02e-08315139204703
Pubmed

Ryanodine receptors are expressed in epidermal keratinocytes and associated with keratinocyte differentiation and epidermal permeability barrier homeostasis.

RYR1 RYR2 RYR3

8.02e-083151321881589
Pubmed

Isoform-dependent formation of heteromeric Ca2+ release channels (ryanodine receptors).

RYR1 RYR2 RYR3

8.02e-083151312213830
Pubmed

Expression of the ryanodine receptor type 3 calcium release channel during development and differentiation of mammalian skeletal muscle cells.

RYR1 RYR2 RYR3

8.02e-08315139242641
Pubmed

Calcineurin upregulates local Ca(2+) signaling through ryanodine receptor-1 in airway smooth muscle cells.

RYR1 RYR2 RYR3

8.02e-083151325239916
Pubmed

A gene-specific cerebral types 1, 2, and 3 RyR protein knockdown induces an antidepressant-like effect in mice.

RYR1 RYR2 RYR3

8.02e-083151318643873
Pubmed

Identification of mutations in the cardiac ryanodine receptor gene in families affected with arrhythmogenic right ventricular cardiomyopathy type 2 (ARVD2).

RYR1 RYR2 RYR3

8.02e-083151311159936
Pubmed

Chromosomal localization of murine ryanodine receptor genes RYR1, RYR2, and RYR3 by in situ hybridization.

RYR1 RYR2 RYR3

8.02e-08315137959768
Pubmed

The organization of proteins in the human red blood cell membrane. A review.

RYR1 RYR2 RYR3

8.02e-08315134600883
Pubmed

Regulation of mouse egg activation: presence of ryanodine receptors and effects of microinjected ryanodine and cyclic ADP ribose on uninseminated and inseminated eggs.

RYR1 RYR2 RYR3

8.02e-08315137635066
Pubmed

Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.

RAB12 PCBP3 PDPR FKBP9 PTPN23 SBSN RPL23 SLC25A12 AKAP9 DPP9 NDUFAF1 CLCN6 LNPEP EIF4A1 EIF4A2 UGDH IQSEC1 C1R UGGT2 FAM3C UQCRC2 POGLUT2 PARP12

8.07e-0814511512330550785
Pubmed

Proteomic identification of common SCF ubiquitin ligase FBXO6-interacting glycoproteins in three kinds of cells.

HNRNPDL VPS4A SMCHD1 SUN1 HUWE1 HEPH PPM1B RPL23 SLC25A12 LNPEP EIF4A1 AFG3L2 UGGT2 UQCRC2 PCBP2

8.26e-086131511522268729
Pubmed

Coordinated changes in cellular behavior ensure the lifelong maintenance of the hippocampal stem cell population.

HUWE1 SLC1A3 MKI67

3.20e-074151333581058
Pubmed

Ryanodine receptor calcium release channels: lessons from structure-function studies.

RYR1 RYR2 RYR3

3.20e-074151323413940
Pubmed

Partial cloning and differential expression of ryanodine receptor/calcium-release channel genes in human tissues including the hippocampus and cerebellum.

RYR1 RYR2 RYR3

3.20e-07415139607712
Pubmed

Conserved and divergent functions of Nfix in skeletal muscle development during vertebrate evolution.

RYR1 RYR2 RYR3

3.20e-074151323482488
Pubmed

A glutathione deficit alters dopamine modulation of L-type calcium channels via D2 and ryanodine receptors in neurons.

RYR1 RYR2 RYR3

3.20e-074151318206662
Pubmed

Requirement for the ryanodine receptor type 3 for efficient contraction in neonatal skeletal muscles.

RYR1 RYR2 RYR3

3.20e-07415139384575
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

HNRNPDL VPS4A SMCHD1 SRP54 PTPN23 URB2 HUWE1 RPL23 NAA35 SLC25A12 EIF4A1 AFG3L2 UGDH MKI67 IQSEC1 ZBTB10 UQCRC2 RIOK2 UTRN ALDH7A1 PARP12

4.43e-0713531512129467282
Pubmed

Presenilins regulate calcium homeostasis and presynaptic function via ryanodine receptors in hippocampal neurons.

RYR1 RYR2 RYR3

7.97e-075151323918386
Pubmed

Protein kinase C-epsilon regulates local calcium signaling in airway smooth muscle cells.

RYR1 RYR2 RYR3

7.97e-075151319011160
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

DMXL2 DAZAP2 CAMK1 HUWE1 RYR3 FOCAD ZNF334 SBNO1 SCG2 MORF4L1 EIF4A1 EIF4A2 FMN2 DAAM2 CHD6 IFT122 PC ST18 UTRN ALDH5A1

8.19e-0712851512035914814
Pubmed

Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.

SMCHD1 ZNF629 SRP54 HUWE1 THOC2 CCDC61 ZNF608 AFG3L2 KIF14 ROCK1 CHD6 TAGLN2 UTRN ARHGEF6

9.50e-076451511425281560
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

DMXL2 MIA3 RAPGEF6 ZNF629 CUL5 EIF4A1 AFG3L2 UGDH UGGT2 IFT122 UQCRC2 RIOK2 PRRC2B PARP12

1.04e-066501511438777146
Pubmed

Prediction of the coding sequences of unidentified human genes. II. The coding sequences of 40 new genes (KIAA0041-KIAA0080) deduced by analysis of cDNA clones from human cell line KG-1.

DAZAP2 CUL7 SLC1A3 CLCN6 KIF14

1.08e-064215157584044
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

DMXL2 MIA3 IQGAP2 HUWE1 SLC1A3 FAM81A ITIH4 AKAP9 KIAA1217 MORF4L1 EIF4A1 EIF4A2 IQSEC1 CDK5RAP2 ROCK1 CDH10 PRRC2B

1.09e-069631511728671696
Pubmed

Membrane depolarization causes a direct activation of G protein-coupled receptors leading to local Ca2+ release in smooth muscle.

RYR1 RYR2 RYR3

1.59e-066151319549818
Pubmed

Rectification of muscle and nerve deficits in paralyzed ryanodine receptor type 1 mutant embryos.

RYR1 RYR2 RYR3

1.59e-066151326025922
Pubmed

Roles of I(f) and intracellular Ca2+ release in spontaneous activity of ventricular cardiomyocytes during murine embryonic development.

RYR1 RYR2 RYR3

1.59e-066151323463619
Pubmed

FKBP12.6 and cADPR regulation of Ca2+ release in smooth muscle cells.

RYR1 RYR2 RYR3

1.59e-066151314592808
Pubmed

Essential Roles of Intracellular Calcium Release Channels in Muscle, Brain, Metabolism, and Aging.

RYR1 RYR2 RYR3

1.59e-066151325966694
Pubmed

HIV-1 Tat activates neuronal ryanodine receptors with rapid induction of the unfolded protein response and mitochondrial hyperpolarization.

RYR1 RYR2 RYR3

1.59e-066151319009018
Pubmed

A calcium-induced calcium release mechanism supports luteinizing hormone-induced testosterone secretion in mouse Leydig cells.

RYR1 RYR2 RYR3

1.59e-066151320519450
Pubmed

IP3Rs are sufficient for dendritic cell Ca2+ signaling in the absence of RyR1.

RYR1 RYR2 RYR3

1.59e-066151316844763
Pubmed

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.

IQGAP2 SMCHD1 WRN SRP54 THOC2 ITIH3 SBSN SNRPGP15 AKAP9 UGDH MKI67 IQSEC1 RAB2B TAGLN2 UQCRC2 PC RIOK2 PCBP2 PRRC2B PARP12

2.20e-0613711512036244648
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

HNRNPDL SMCHD1 SUN1 URB2 HUWE1 CUL7 THOC2 SNRPGP15 RPL23 EIF4A1 AFG3L2 MKI67 KIF14 TAGLN2 UQCRC2 PCBP2 UTRN

2.48e-0610241511724711643
Pubmed

KAP1 facilitates reinstatement of heterochromatin after DNA replication.

HNRNPDL PDPR IQGAP2 SRP54 PTPN23 URB2 HUWE1 RPL23 PTPN2 SLC25A12 EIF4A1 EIF4A2 UQCRC2 PC

2.63e-067041511429955894
Pubmed

Developmental expression of the calcium release channels during early neurogenesis of the mouse cerebral cortex.

RYR1 RYR2 RYR3

2.77e-067151311860456
Pubmed

Human immunodeficiency virus-1 Tat activates calpain proteases via the ryanodine receptor to enhance surface dopamine transporter levels and increase transporter-specific uptake and Vmax.

RYR1 RYR2 RYR3

2.77e-067151320962236
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

RAPGEF6 SMCHD1 SRP54 PTPN23 THOC2 RPL23 ORC2 KIAA1217 AFG3L2 MKI67 TAGLN2 PC PCBP2 UTRN PRRC2B PARP12

3.37e-069341511633916271
Pubmed

Voltage-dependent conformational changes of Kv1.3 channels activate cell proliferation.

DNHD1 THOC2 RYR1 RPL23 EIF4A1 AFG3L2 CDK5RAP2 POLQ

3.82e-06208151833230847
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

DMXL2 IQGAP2 PCLO FKBP9 PSD3 SLC1A3 CUL5 RPL23 THBS4 SLC25A12 CLCN6 KIAA1217 SCN2A AFG3L2 IQSEC1 UQCRC2 PC UTRN ALDH7A1 PRRC2B

4.18e-0614311512037142655
Pubmed

Sequential docking, molecular differentiation, and positioning of T-Tubule/SR junctions in developing mouse skeletal muscle.

RYR1 RYR2 RYR3

4.42e-068151311784029
Pubmed

Roles of IP3R and RyR Ca2+ channels in endoplasmic reticulum stress and beta-cell death.

RYR1 RYR2 RYR3

4.42e-068151319033399
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

RAPGEF6 SWAP70 SMCHD1 USP24 PTPN23 HUWE1 THOC2 KIF14 TAGLN2 PC PCBP2 PRRC2B

5.46e-065491511238280479
Pubmed

Cell cycle-dependent phosphorylation regulates RECQL4 pathway choice and ubiquitination in DNA double-strand break repair.

HNRNPDL GINS3 SRP54 HUWE1 SBSN CUL5 SNRPGP15 RPL23 ORC2 SLC25A12 MORF4L1 EIF4A1 AFG3L2 ZBTB10 UQCRC2 PC RIOK2 PCBP2 ALDH7A1

5.74e-0613351511929229926
Pubmed

Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.

SUMF2 SRP54 URB2 SLC1A3 B3GAT3 PPM1A AKAP9 SBNO1 CEP250 CDK5RAP2 UGGT2 POGLUT2 ALDH7A1 PRRC2B

5.76e-067541511433060197
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

GINS3 ARHGAP10 VPS4A ZNF629 CUL7 ITIH4 ARHGAP4 NAA35 SLC25A12 ZNF608 KMT5B MORF4L1 AFG3L2 IQSEC1 ZBTB10 FMN2 PRRC2B

7.72e-0611161511731753913
Pubmed

A High-Density Human Mitochondrial Proximity Interaction Network.

HNRNPDL MIA3 PDPR PCLO SUN1 SRP54 HUWE1 CUL7 SPTBN5 RPL23 PTPN2 SLC25A12 AKAP9 NDUFAF1 KIAA1217 AFG3L2 CDK5RAP2 UQCRC2 ALDH5A1 PRRC2B

8.05e-0614961512032877691
Pubmed

Functional consequences of necdin nucleocytoplasmic localization.

DAZAP2 CAMK1 HUWE1 TYW1B TYW1

8.95e-0664151522442722
Pubmed

LncRNAs-directed PTEN enzymatic switch governs epithelial-mesenchymal transition.

TDRD15 RAPGEF6 PKD1L2 RYR2 RYR3 FSIP2 AFG3L2

9.32e-06168151730631154
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

DMXL2 MIA3 PCLO SUN1 USP24 PSD3 HUWE1 SLC1A3 RYR2 RPL23 PTPN2 KIAA1217 AFG3L2 IQSEC1 UQCRC2 PC ALDH5A1

1.01e-0511391511736417873
Pubmed

Functional proteomics mapping of a human signaling pathway.

SUMF2 SASH1 DAZAP2 HUWE1 RYR2 CUL5 LNPEP CEP250 ROCK1 CHD6 PCBP2 UTRN

1.14e-055911511215231748
Pubmed

Heterozygous deletion of chromosome 17p renders prostate cancer vulnerable to inhibition of RNA polymerase II.

HNRNPDL RAPGEF6 CUL7 CUL5 EIF4A1 UQCRC2 PC PCBP2

1.23e-05244151830349055
Pubmed

Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.

MIA3 PCLO HUWE1 RYR1 RPL23 NAA35 AKAP9 EIF4A1 DAAM2 ZNF561 TAGLN2 PC PCBP2 UTRN

1.24e-058071511430575818
Pubmed

Regulation of epidermal differentiation through KDF1-mediated deubiquitination of IKKα.

ZNF629 THOC2 PPM1B IQSEC1 UQCRC2 PC PCBP2

1.57e-05182151732239614
Pubmed

New molecular components supporting ryanodine receptor-mediated Ca(2+) release: roles of junctophilin and TRIC channel in embryonic cardiomyocytes.

RYR1 RYR2 RYR3

1.72e-0512151319095005
Pubmed

Notch-induced Asb2 expression promotes protein ubiquitination by forming non-canonical E3 ligase complexes.

CUL7 CUL5 JAK2

1.72e-0512151321119685
Pubmed

Contractile impairment and structural alterations of skeletal muscles from knockout mice lacking type 1 and type 3 ryanodine receptors.

RYR1 RYR3

1.87e-05215129489997
Pubmed

Skeletal and cardiac ryanodine receptors exhibit different responses to Ca2+ overload and luminal ca2+.

RYR1 RYR2

1.87e-052151217259277
Pubmed

Association analysis between suicidal behaviour and candidate genes of bipolar disorder and schizophrenia.

ITIH3 ITIH4

1.87e-052151224461634
Pubmed

The block of ryanodine receptors selectively inhibits fetal myoblast differentiation.

RYR1 RYR3

1.87e-052151212640042
Pubmed

Ryanodine receptor oligomeric interaction: identification of a putative binding region.

RYR1 RYR2

1.87e-052151214722100
Pubmed

Translational dysregulation in cancer: eIF4A isoforms and sequence determinants of eIF4A dependence.

EIF4A1 EIF4A2

1.87e-052151226614665
Pubmed

Differential expression of the murine eukaryotic translation initiation factor isogenes eIF4A(I) and eIF4A(II) is dependent upon cellular growth status.

EIF4A1 EIF4A2

1.87e-05215129015395
Pubmed

Structural and functional interactions within ryanodine receptor.

RYR1 RYR2

1.87e-052151226009179
Pubmed

Structure and Function of the Human Ryanodine Receptors and Their Association with Myopathies-Present State, Challenges, and Perspectives.

RYR1 RYR2

1.87e-052151232899693
Pubmed

Possible involvement of ryanodine receptor-mediated intracellular calcium release in the effect of corticotropin-releasing factor on adrenocorticotropin secretion.

RYR1 RYR3

1.87e-052151214592949
Pubmed

Tissue-specific alternative splicing of mouse brain type ryanodine receptor/calcium release channel mRNA.

RYR2 RYR3

1.87e-05215128898078
Pubmed

The mouse sino-atrial node expresses both the type 2 and type 3 Ca(2+) release channels/ryanodine receptors.

RYR2 RYR3

1.87e-052151214550562
Pubmed

ITIH3 and ITIH4 polymorphisms and depressive symptoms during pregnancy in Japan: the Kyushu Okinawa Maternal and Child Health Study.

ITIH3 ITIH4

1.87e-052151229992445
Pubmed

Morphological abnormalities of adrenal gland and hypertrophy of liver in mutant mice lacking ryanodine receptors.

RYR1 RYR3

1.87e-05215129799464
Pubmed

Ryanodine receptors in human pancreatic beta cells: localization and effects on insulin secretion.

RYR1 RYR2

1.87e-052151215033925
Pubmed

Dephosphorylation of cyclin-dependent kinases by type 2C protein phosphatases.

PPM1A PPM1B

1.87e-052151210580002
Pubmed

Expression and functional activity of ryanodine receptors (RyRs) during skeletal muscle development.

RYR1 RYR3

1.87e-052151217118445
Pubmed

RyR3 amplifies RyR1-mediated Ca(2+)-induced Ca(2+) release in neonatal mammalian skeletal muscle.

RYR1 RYR3

1.87e-052151211500519
Pubmed

Discovery of a gene family critical to wyosine base formation in a subset of phenylalanine-specific transfer RNAs.

TYW1B TYW1

1.87e-052151216162496
Pubmed

Altered ryanodine receptor expression in mild cognitive impairment and Alzheimer's disease.

RYR2 RYR3

1.87e-052151221531043
Pubmed

Modulation of calcium signalling by dominant negative splice variant of ryanodine receptor subtype 3 in native smooth muscle cells.

RYR2 RYR3

1.87e-052151216678258
Pubmed

A cellular response linking eIF4AI activity to eIF4AII transcription.

EIF4A1 EIF4A2

1.87e-052151222589333
Pubmed

Principal mutation hotspot for central core disease and related myopathies in the C-terminal transmembrane region of the RYR1 gene.

RYR1 RYR3

1.87e-052151212565913
Pubmed

Functional and morphological features of skeletal muscle from mutant mice lacking both type 1 and type 3 ryanodine receptors.

RYR1 RYR3

1.87e-05215129192302
Pubmed

Isolation and partial cloning of ryanodine-sensitive Ca2+ release channel protein isoforms from human myometrial smooth muscle.

RYR1 RYR3

1.87e-05215127556644
Pubmed

Regulation of eukaryotic initiation factor 4AII by MyoD during murine myogenic cell differentiation.

EIF4A1 EIF4A2

1.87e-052151224466343
Pubmed

Ryanodine receptors in muscarinic receptor-mediated bronchoconstriction.

RYR1 RYR3

1.87e-052151215894801
Pubmed

Recent advances in understanding the ryanodine receptor calcium release channels and their role in calcium signalling.

RYR1 RYR2

1.87e-052151230542613
Pubmed

Ryanodine receptors are expressed and functionally active in mouse spermatogenic cells and their inhibition interferes with spermatogonial differentiation.

RYR1 RYR2

1.87e-052151215280431
Pubmed

The mouse protein synthesis initiation factor 4A gene family includes two related functional genes which are differentially expressed.

EIF4A1 EIF4A2

1.87e-05215123046931
InteractionCDC42 interactions

IQGAP2 ARHGAP10 CDC42SE1 SUN1 WRN FKBP9 PSD3 CASP7 URB2 HUWE1 SLC1A3 RPL23 PTPN2 SBNO1 LNPEP AFG3L2 UGDH MKI67 FMN2 KIF14 ROCK1 TYW1 UQCRC2 UTRN ARHGEF6 EPHA5

4.84e-06132315026int:CDC42
Cytoband7p11.1

FKBP9 FKBP9P1

1.07e-05215127p11.1
Cytoband5q15

LNPEP SPATA9 RIOK2

3.15e-044015135q15
Cytoband2q24

SLC25A12 ABCB11

5.80e-041115122q24
GeneFamilyRyanodine receptors|Protein phosphatase 1 regulatory subunits

RYR1 RYR2 RYR3

1.74e-0731023287
GeneFamilyEF-hand domain containing

CAPN14 SWAP70 FSTL5 FKBP9 RYR2 RYR3 SLC25A12

2.42e-042191027863
GeneFamilyCullins

CUL7 CUL5

8.63e-04810221032
GeneFamilyATP binding cassette subfamily B

ABCB5 ABCB11

1.68e-03111022806
GeneFamilyCD molecules|Type II classical cadherins

CDH10 CDH12

2.36e-031310221186
GeneFamilyRho GTPase activating proteins|BCH domain containing

ARHGAP42 ARHGAP10 ARHGAP4

2.82e-03501023721
GeneFamilyProtein phosphatases, Mg2+/Mn2+ dependent

PPM1A PPM1B

4.06e-03171022701
GeneFamilyProtein tyrosine phosphatases, non-receptor type

PTPN23 PTPN2

4.55e-03181022812
GeneFamilyAldehyde dehydrogenases

ALDH5A1 ALDH7A1

5.06e-03191022398
GeneFamilyWnt family|Endogenous ligands

WNT2 WNT5B

5.06e-03191022360
CoexpressionGSE3982_DC_VS_TH2_DN

GINS3 B3GAT3 RYR2 THBS4 ZNF334 TAGLN2 POGLUT2 POLQ ARHGEF6

2.44e-061991519M5486
CoexpressionTHUM_SYSTOLIC_HEART_FAILURE_DN

SMCHD1 PSD3 PKD1L2 PPM1A PTPN2 KMT5B KIAA1217 UQCRC2 PCBP2

7.12e-062271519M18441
CoexpressionGSE45881_CXCR6HI_VS_CXCR1LO_COLONIC_LAMINA_PROPRIA_UP

MIA3 RAPGEF6 USP24 SRP54 THOC2 CDC14A IQSEC1 PARP12

2.18e-052001518M9889
CoexpressionGSE17721_PAM3CSK4_VS_GADIQUIMOD_24H_BMDC_UP

CDC42SE1 HEPH RPL23 JAK2 KIAA1217 MKI67 UQCRC2 MARCO

2.18e-052001518M3979
CoexpressionGEORGES_CELL_CYCLE_MIR192_TARGETS

CDC14A CUL5 MKI67 KIF14 POLQ

2.95e-05621515M11038
CoexpressionLAKE_ADULT_KIDNEY_C2_PODOCYTES

IQGAP2 PSD3 CDC14A RYR3 ST6GALNAC3 FMN2 ROCK1 UTRN

3.31e-052121518M39221
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

HNRNPDL DMXL2 SASH1 SWAP70 SMCHD1 WRN USP24 PSD3 THOC2 PPM1B ORC2 PTPN2 SLC25A12 AKAP9 KIF14 ROCK1

3.67e-0585615116M4500
CoexpressionHE_LIM_SUN_FETAL_LUNG_C7_PROLIFERATING_SCHWANN_CELL

ARHGAP42 GINS3 CCDC9B IQGAP2 FAHD2A CASP7 CAMK1 CDC14A HEPH JAK2 ARHGAP4 MKI67 KIF14 C1R POLQ PC UTRN ARHGEF6

3.82e-05105415118M45798
CoexpressionAtlasFacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_2500_k-means-cluster#1

RAB12 TTC39B IQGAP2 PCLO ZNF629 PSD3 SLC1A3 SLC25A12 CLCN6 ST18 ARHGEF6

1.03e-0530614811Facebase_RNAseq_e10.5_Maxillary Arch_2500_K1
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MIA3 COL6A6 PCLO HUWE1 AKAP9 SCG2 FMN2 PC ST18

2.33e-0819515193e519cffa6144a62b06124642a14c9ff39b76554
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MIA3 COL6A6 PCLO HUWE1 AKAP9 SCG2 FMN2 PC ST18

2.33e-0819515197796ea9247f4c63762f0de8490fed08b9717fa23
ToppCellLPS-antiTNF-Unknown-Endothelial-Pericyte_2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PCBP3 RYR2 RYR3 MKI67 KIF14 DAAM2 POLQ

3.46e-07132151702491930097b75aaeedab9e8200711b0dc610944
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Upper_Layer|World / Primary Cells by Cluster

PCLO PSD3 RYR2 PTPN2 AKAP9 SCG2 EIF4A2 SCN2A

4.27e-072001518db10f76938af553d1a2275bb02ef75dff3c3135b
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Upper_Layer-21|World / Primary Cells by Cluster

PCLO PSD3 RYR2 PTPN2 AKAP9 SCG2 EIF4A2 SCN2A

4.27e-07200151830a3e4aee12ec1b5acdce90f86c9733c27a7f6fc
ToppCellfacs-Trachea-24m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l6-17|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CCDC9B HEPH ITIH4 GPR179 SCN2A POLQ ST18

2.48e-0617715178abdf1d970b2f15e17e185f3e612dd5065c88757
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCLO PKD1L2 RYR2 RYR3 SCN2A ST18 EPHA5

3.21e-0618415172cbed6462fea2622871bb7e49b0df3d984239281
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARHGAP42 PCBP3 COL6A6 PSD3 RYR2 LRP6 DAAM2

3.21e-061841517689a8af81a79a4bb3123cfa01958c953eab5de98
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCLO PKD1L2 RYR2 RYR3 SCN2A ST18 EPHA5

3.21e-061841517ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCLO PKD1L2 RYR2 RYR3 SCN2A ST18 EPHA5

3.21e-0618415172b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellCV-Moderate-7|Moderate / Virus stimulation, Condition and Cluster

TTC39B DMXL2 SMCHD1 SUN1 HUWE1 KIF14 POLQ

3.32e-061851517a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCellCV-Moderate-7|CV / Virus stimulation, Condition and Cluster

TTC39B DMXL2 SMCHD1 SUN1 HUWE1 KIF14 POLQ

3.44e-0618615178571956890fc9894d766ba294a28e376b4aba428
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_2_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

COL6A6 ARHGAP10 SLC1A3 WNT5B JAK2 PTPN2 C1R

3.96e-0619015170fea33f2dc1efa23aaa2da1c318482a52a313ff1
ToppCellsevere-low-quality_cells|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

TTC39B SMCHD1 USP24 CDC14A AKAP9 LNPEP UTRN

4.39e-0619315179337bc93e3904c7fc7c93c328518bcd6453b1e8c
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-3.5_mon-Proliferating-Cycling_Progenitors|3.5_mon / Sample Type, Dataset, Time_group, and Cell type.

IQGAP2 SLC1A3 MKI67 KIF14 TAGLN2 POLQ UTRN

4.86e-0619615175905f0e3061a6b98b7a33d64c782c3dda2cd51ef
ToppCellsevere-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

TTC39B SMCHD1 USP24 CDC14A AKAP9 LNPEP UTRN

5.02e-06197151757ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligoastrocytoma|TCGA-Brain / Sample_Type by Project: Shred V9

FSTL5 RYR1 SLC22A6 DAAM2 PC ALDH5A1

1.86e-051611516347edb0de10850b7d16c40945751033289289c9b
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PCBP3 WNT2 MKI67 KIF14 CDK5RAP2 POLQ

2.28e-051671516bc132b51dec4e8f1cd2b2cd89f83641976e09292
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

IQGAP2 CDC14A RYR3 ST6GALNAC3 FMN2 CDH10

2.36e-051681516fc80e4fecfc92458eb627013a983041d8ca025a9
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

IQGAP2 CDC14A RYR3 ST6GALNAC3 FMN2 CDH10

2.36e-051681516315ca578c945aeeb77acda2727f3e6db8b43f43e
ToppCelldroplet-Liver-HEPATOCYTES-1m-Epithelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITIH3 ITIH4 UGDH ABCB11 PC ABCG8

2.36e-051681516b98af4043dfa5dfa4413e482879fad88de484675
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

IQGAP2 CDC14A RYR3 ST6GALNAC3 FMN2 CDH10

2.36e-051681516e96859dbf51cf8c4def8ee8db132f4d874fb4381
ToppCelldroplet-Liver-HEPATOCYTES-1m-Epithelial-hepatocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITIH3 ITIH4 UGDH ABCB11 PC ABCG8

2.36e-051681516073b53d4cee6bc8c5c6fce51cf6cd9c316478f69
ToppCelldroplet-Liver-HEPATOCYTES|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITIH3 ITIH4 UGDH ABCB11 PC ABCG8

2.44e-051691516f195467438c589f87224bde7da720dea072d110c
ToppCelldroplet-Liver-HEPATOCYTES-1m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITIH3 ITIH4 UGDH ABCB11 PC ABCG8

2.44e-0516915167785cab967a33560830c394c918d6ce625103858
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

IQGAP2 CDC14A RYR3 ST6GALNAC3 FMN2 CDH10

2.69e-051721516381ae1c3c07d0a424f43455ec571653b192a946a
ToppCellCOVID-19-kidney-PCT-S3-2|kidney / Disease (COVID-19 only), tissue and cell type

TDRD15 ITIH3 ITIH4 ABCB11 C1R ABCG8

2.87e-0517415165aa2fb631505600f37d2b87b02def7be139dc262
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

IQGAP2 CDC14A RYR3 ST6GALNAC3 FMN2 CDH10

2.87e-051741516dbdcdec08f1fc69fcdb5d8a6d78df8ef9c374d89
ToppCelldroplet-Liver-HEPATOCYTES-1m-Epithelial-Hepatocyte_(Periportal)|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP2F1 ITIH3 ITIH4 ABCB11 PC ABCG8

2.97e-0517515165c38d4b6c03473d841e6203a7efaa6dcb2d59386
ToppCellCOVID-19-kidney-Podocyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

IQGAP2 CDC14A FAM81A RYR3 ST6GALNAC3 FMN2

2.97e-051751516a73e3a65fd5c1e09cb0c2dae20c1a7bfcae49223
ToppCell5'-GW_trimst-2-LargeIntestine-Neuronal-neurons_A|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PCBP3 GPR179 SCG2 SCN2A ST18 EPHA5

3.06e-051761516116741fef5895ca85057d2d31eca9eba5764ab44
ToppCell5'-GW_trimst-2-LargeIntestine-Neuronal-neurons_A-Branch_A1_(iMN)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PCBP3 GPR179 SCG2 SCN2A ST18 EPHA5

3.06e-0517615165b707f58d164ee7a6a527dd5d053472ce9a631c1
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

IQGAP2 CDC14A FAM81A RYR3 ST6GALNAC3 FMN2

3.16e-0517715164d2cdb57b427a42085c5f9affa0967b15e84dec3
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

IQGAP2 CDC14A FAM81A RYR3 ST6GALNAC3 FMN2

3.26e-051781516edc7143dc9959d36057cb9471681a23afcbc8cce
ToppCell10x5'-lymph-node_spleen-Myeloid_Mac-Cycling_Myeloid-Mac|lymph-node_spleen / Manually curated celltypes from each tissue

DMXL2 SASH1 SLC1A3 MKI67 KIF14 MARCO

3.48e-0518015164eea8366cdb82c356325ce88f09ad8b302c17a07
ToppCellEpithelial-lung_neuroendocrine_cell_(PNEC)|World / Lineage, Cell type, age group and donor

PCBP3 PCLO SCG2 SCN2A FMN2 ST18

3.70e-05182151657bf4ffb304324e2e392e196336a530d9f78fe0d
ToppCelldroplet-Spleen-nan-18m|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HNRNPDL SWAP70 SMCHD1 SRP54 ZNF608 LNPEP

3.70e-051821516eeb5dfa4539e9ca5220f26bc2b65717ddcf13b6c
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

IQGAP2 CDC14A FAM81A RYR3 ST6GALNAC3 FMN2

3.81e-0518315163c516fe5083f02bad1f464ed284010b4131a833c
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

IQGAP2 CDC14A FAM81A RYR3 ST6GALNAC3 FMN2

3.81e-0518315169c2689d76fc6d30f5ab093428aa669d0a98953cf
ToppCelldroplet-Marrow-nan-3m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SMCHD1 SRP54 ZNF608 LNPEP EIF4A2 UTRN

3.93e-0518415161154a5ad7b8512272b7476f949ddac350910bfb7
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

IQGAP2 CDC14A FAM81A RYR3 ST6GALNAC3 FMN2

3.93e-0518415167294b379ce4cb8fa75e432559082f93cd106aaf5
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_VIP_PRSS8|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ARHGAP42 ABCB5 FSTL5 ZNF608 SCG2 PNOC

4.05e-0518515164c42bd3cd72f91f4d4ebb849069a03761a2cd662
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

PCLO RYR2 SCN2A DAAM2 ROCK1 PIWIL3

4.17e-05186151623b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCellFetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

PCBP3 PCLO SCG2 SCN2A FMN2 ST18

4.17e-051861516b45cce768e4bf91da194fd9660cab7520dfb15ac
ToppCellAdult-Epithelial-club_cell-D231|Adult / Lineage, Cell type, age group and donor

ARHGAP42 CYP2F1 WNT5B CELSR1 ZNF608 KIAA1217

4.30e-051871516ee59d7d3de5879738ff0b9c3ea5e4847fb48cb86
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

IQGAP2 CDC14A RYR3 ST6GALNAC3 FMN2 C1R

4.30e-05187151624c2a3962da364e46e98abeab5f8234376fa26bb
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

SMCHD1 USP24 HUWE1 CDC14A LNPEP UTRN

4.43e-051881516ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Degenerative_Podocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

IQGAP2 CDC14A ST6GALNAC3 FMN2 C1R CDH10

4.43e-0518815169db778c1d9e622a68337212296e3a1ed8f771fa5
ToppCellFetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

PCBP3 PCLO SCG2 SCN2A FMN2 ST18

4.43e-051881516c4c3b21ab723b0e9beff9ec84f8d68485f771528
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARHGAP42 PCBP3 PSD3 SLC1A3 RYR2 C1R

4.70e-05190151645df8fee00f8949937863159d7aa042e72748d9b
ToppCellCD8+_Memory_T_cell-CV-7|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

SMCHD1 SUN1 HUWE1 LNPEP TYW1 POLQ

4.84e-0519115169454f642c3621370fa23640b631301346b300950
ToppCellCOVID-19_Severe-Plasmablast|World / disease group, cell group and cell class

ARHGAP42 WNT5B MKI67 FAM3C POLQ PNOC

4.98e-051921516a333053fe2bd206c32790916bfc5fce904ab7f57
ToppCell3'-GW_trimst-2-SmallIntestine-Neuronal-neurons_B|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PCBP3 FSTL5 PCLO SCG2 SCN2A PNOC

4.98e-0519215162f1c4ef693515ccc7231bd8c6641fad51d445d20
ToppCellLPS_only-Stromal_mesenchymal|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARHGAP42 COL6A6 WNT2 SLC1A3 RYR2 C1R

4.98e-051921516162d8b5858d150ecbbd1c9bf2b19c6c9cd50a158
ToppCellLPS-IL1RA-Stromal_mesenchymal|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARHGAP42 WNT2 SLC1A3 RYR2 C1R DAAM2

4.98e-0519215164e47a02007f562f29ba5910df64d32a0167d0bd1
ToppCellPBMC-Severe-Lymphocyte-B-Plasmablast|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

ARHGAP42 SRP54 WNT5B MKI67 FAM3C PNOC

5.12e-051931516227d82059a9f99937e0188ff57f2d0e485ebfe69
ToppCellPBMC-Severe-Lymphocyte-B-Plasmablast-Plasmablast-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

ARHGAP42 SRP54 WNT5B MKI67 FAM3C PNOC

5.12e-05193151638bb14df7f05c29565a1c7f175fafe636e543bf8
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_B|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

SWAP70 SMCHD1 ZNF608 ZBTB10 FAM3C PNOC

5.12e-051931516ac227ddabfb3f021b1b39dba73f898517cd5a58e
ToppCellPBMC-Severe-Lymphocyte-B-Plasmablast-Plasmablast|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

ARHGAP42 SRP54 WNT5B MKI67 FAM3C PNOC

5.12e-0519315163ba6d44248690b80f4caf791d463e60f1ab816c4
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_B|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SWAP70 ABCC6 ZNF608 FAM3C ALDH7A1 PNOC

5.12e-05193151689831e1007944e47719e58f23bfef5f1944cae23
ToppCellCOVID-19_Severe-Plasmablast|COVID-19_Severe / disease group, cell group and cell class

ARHGAP42 SRP54 WNT5B FAM3C POLQ PNOC

5.12e-0519315168074bcede261b85f9ae03ee372bd6d4b40384537
ToppCellPBMC-Severe-Lymphocyte-B-Plasmablast|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ARHGAP42 SRP54 WNT5B MKI67 FAM3C PNOC

5.12e-051931516ce3873ece35fd2155ea235cb3c8bcd235cc0ebde
ToppCellPBMC-Severe-Lymphocyte-B-Plasmablast-Plasmablast|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ARHGAP42 SRP54 WNT5B MKI67 FAM3C PNOC

5.12e-0519315168f57b0473a2c2c07f83e5fe70f16862b1bb3b514
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_B-B_cell|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

SWAP70 SMCHD1 ZNF608 ZBTB10 FAM3C PNOC

5.12e-051931516f4135615ee0118eec9e221becdd67888e0c2a112
ToppCellPBMC-Mild-Myeloid-cDC-cDC-cDC_12|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

FSTL5 FAM81A ZNF334 MKI67 POGLUT2

5.14e-051181515f0f40a0165156e3fc1584480b473b0e84e10d2cc
ToppCellLPS-antiTNF-Stromal_mesenchymal|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARHGAP42 COL6A6 WNT2 SLC1A3 RYR2 C1R

5.27e-0519415166e13549f697f7478b34fe71f7dd9d63c5d3db22e
ToppCellPBMC-Mild-Myeloid-cDC-cDC-cDC_12|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

FSTL5 FAM81A ZNF334 MKI67 POGLUT2

5.35e-051191515a6b359e7aafcc197f53eb5e19c3a905bc09497bb
ToppCellsevere-B_cell|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SWAP70 FAM81A CELSR1 ZNF608 SCN2A PNOC

5.43e-0519515160fc3c605609c9e6bdea15d73c45def2188ae5fb1
ToppCell3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL6A6 SUN1 PSD3 ZNF608 C1R TAGLN2

5.58e-05196151685507488f83d8f71b3ee2ad5e5aa0b6ad6193873
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Layer_VI_Pan-area|World / Primary Cells by Cluster

PCLO PSD3 EIF4A2 SCN2A FAM3C ST18

5.74e-05197151679b9e7f2e8e33b3c547f716be5667156c48b0dfc
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Layer_VI_Pan-area-33|World / Primary Cells by Cluster

PCLO PSD3 EIF4A2 SCN2A FAM3C ST18

5.74e-051971516d20f29088e9afd8a960d6f680075c380e550f8a7
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_basal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CYP2F1 PSD3 WNT5B CELSR1 KIAA1217 ALDH7A1

5.74e-051971516107cb153ea7fc74bbd244dbb9d0499c0a8506724
ToppCellLPS_only-Endothelial-Endothelial-FOXM1|LPS_only / Treatment groups by lineage, cell group, cell type

RYR1 ZNF334 ZNF608 MKI67 KIF14 POLQ

5.74e-051971516038fd92750257d43d5e980fd06d77742b543f11a
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_secretory|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ARHGAP42 CYP2F1 CELSR1 ZNF608 ST6GALNAC3 KIAA1217

5.91e-051981516af399569c718f5fd971d73a7926768c9311002a3
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PCLO RYR2 FOCAD SCN2A FMN2 CDH12

5.91e-0519815168ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCellCOVID-19-COVID-19_Severe-Lymphocyte-B-Plasmablast|COVID-19_Severe / Disease, condition lineage and cell class

ARHGAP42 SRP54 WNT5B MKI67 FAM3C PNOC

6.07e-051991516e6422b65e22e5aa8dfaebdae5be76dd78b978604
ToppCellmild-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

TTC39B SMCHD1 USP24 CDC14A AKAP9 UTRN

6.07e-051991516f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCellFibroblasts|World / lung cells shred on cell class, cell subclass, sample id

COL6A6 WNT2 HEPH ITIH3 RYR2 C1R

6.07e-051991516e2b6752fcabd5249a166486ae6796f2c97c1fcaf
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Parietal_and_Temporal-6|World / Primary Cells by Cluster

PCLO PSD3 RYR2 AKAP9 EIF4A2 SCN2A

6.07e-0519915161b1bccf4293f11048709d15a3c892c0edf3da3d2
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

USP24 THBS4 KIAA1217 SCN2A LRP6 CDH10

6.07e-05199151619a97e27a4758e794ce7246d295e112b47931a48
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Parietal_and_Temporal|World / Primary Cells by Cluster

PCLO PSD3 RYR2 AKAP9 EIF4A2 SCN2A

6.07e-0519915164bee94c116c0da5eba951cb4cea7cc9dcdd6e30f
ToppCellNeuronal-Inhibitory-iA-iA_1(SST_PAX6)-PAX6-TSPAN12-L1-2|Neuronal / cells hierarchy compared to all cells using T-Statistic

ARHGAP42 ABCB5 FSTL5 ZNF608 SCG2 PNOC

6.24e-052001516523d799eb315b33b77e02d5b7db63dad8450c4e1
ToppCellcontrol|World / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

PCLO SUN1 CELSR1 AKAP9 KIAA1217 CPLANE1

6.24e-05200151697f36d2c197e03d93a1fc59949d77ae90f6e6a9a
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Astrocyte-Astrocyte-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

FSTL5 PKD1L2 SLC1A3 HEPH RYR3 SLC22A6

6.24e-0520015167a8160e6477708f22e48c609bf8f43f3715dcb03
ToppCellNeuronal-Inhibitory-iA-iA_1(SST_PAX6)-PAX6-TSPAN12|Neuronal / cells hierarchy compared to all cells using T-Statistic

ARHGAP42 ABCB5 FSTL5 ZNF608 SCG2 PNOC

6.24e-052001516e5cef95e563a6e793ade190ce88c999bfa0af460
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Astrocyte-Astrocyte|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SASH1 SLC1A3 HEPH RYR3 SLC22A6 ABCB11

6.24e-052001516d0812817ef99608994193787a62d39adeb2070ca
ToppCellNeuronal-Inhibitory-iA-iA_1(SST_PAX6)-NMBR|Neuronal / cells hierarchy compared to all cells using T-Statistic

ARHGAP42 FSTL5 ZNF608 SCG2 UTRN PNOC

6.24e-052001516862db57d043bdf3cb059fbfc8b29bc1eafdf64ec
ToppCellNeuronal-Inhibitory-iA-iA_1(SST_PAX6)-NMBR--L1|Neuronal / cells hierarchy compared to all cells using T-Statistic

ARHGAP42 FSTL5 ZNF608 SCG2 UTRN PNOC

6.24e-052001516a91345f268f13170c27309333603eb82400c9947
ToppCellNeuronal-Excitatory-eB(RORB)-SEMA3E-|Neuronal / cells hierarchy compared to all cells using T-Statistic

SASH1 FSTL5 PCLO C1R FAM3C CDH10

6.24e-0520015161a3d29a580d1b405a74869a1da3e818c581fc559
ToppCellControl_saline-Mesenchymal_myocytic-Pericyte|Control_saline / Treatment groups by lineage, cell group, cell type

ARHGAP42 COL6A6 FAM81A ITIH3 RYR2 DAAM2

6.24e-052001516cb7ef774b6d300f8019c5b16a04e3ebd165e4f1c
ToppCellmild-B_naive|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SWAP70 SMCHD1 ZNF608 ZBTB10 FAM3C PNOC

6.24e-052001516222789b897e2a683bbfd1d00b6fd8705015d90df
ToppCellNeuronal-Excitatory-eB(RORB)-SEMA3E---L4-6|Neuronal / cells hierarchy compared to all cells using T-Statistic

SASH1 FSTL5 PCLO C1R FAM3C CDH10

6.24e-0520015166f9ed8fe9cda91185c3a1a675353e11b8fec6ef1
ToppCellNeuronal-Inhibitory-iA-iA_1(SST_PAX6)-NMBR-|Neuronal / cells hierarchy compared to all cells using T-Statistic

ARHGAP42 FSTL5 ZNF608 SCG2 UTRN PNOC

6.24e-052001516d416a7be1a4e6232fb58a9687774da24821f1fdd
ToppCellControl_saline-Mesenchymal_myocytic-Pericyte-Pericyte_3|Control_saline / Treatment groups by lineage, cell group, cell type

ARHGAP10 FAM81A ITIH3 RYR2 DAAM2 DYRK3

6.24e-052001516b0866b497aa71d06cef25f9a335fa584e95fa7e0
ToppCellNeuronal-Excitatory-eB(RORB)-SEMA3E--|Neuronal / cells hierarchy compared to all cells using T-Statistic

SASH1 FSTL5 PCLO C1R FAM3C CDH10

6.24e-05200151686705dfc05b3e1576543b93883c88fb55b742855
ToppCellNeuronal-Excitatory-eB(RORB)-SEMA3E|Neuronal / cells hierarchy compared to all cells using T-Statistic

SASH1 FSTL5 PCLO C1R FAM3C CDH10

6.24e-052001516db194b4f524fd008b3c5b4b6014b436190a1b87a
ToppCellNS-control|NS / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

PCLO SUN1 CELSR1 AKAP9 KIAA1217 CPLANE1

6.24e-052001516ecbe89ff95d046155b984c8c150e0b9e7278f839
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Astrocyte|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SASH1 SLC1A3 HEPH RYR3 SLC22A6 ABCB11

6.24e-052001516cd54ddf1919c98e84b7e4aba85b374fc8b407206
ToppCellE16.5-samps-Mesenchymal-Myofibroblast-myofibroblast_-_immature|E16.5-samps / Age Group, Lineage, Cell class and subclass

COL6A6 ITIH3 ABCB11 CDK5RAP2 PNOC

7.85e-0512915155e4783cc63afdeaebdfaecb72f95f3efc8d3c4a3
ToppCellPBMC-Control-Lymphocyte-B-B_cell-B_naive-B_naive-4|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SWAP70 ZNF608 SCN2A DAAM2 PNOC

9.39e-0513415158707210b2a5d33baa1d204e9e2ed8921181cb309
Drugcis-diammineplatinum(II

RYR1 RYR2 RYR3

2.69e-0731483CID000159790
Drug2-hydroxyheptanoic acid

RYR1 RYR2 RYR3

2.69e-0731483CID002750949
Drug8N3-cADPR

RYR1 RYR2 RYR3

2.69e-0731483CID000127713
Drugaminodantrolene

RYR1 RYR2 RYR3

2.69e-0731483CID009570289
Drug2-hydroxycarbazole

RYR1 RYR2 RYR3

2.69e-0731483CID000093551
DrugRyanodyl 3-(pyridine-3-carboxylate

RYR1 RYR2 RYR3

2.69e-0731483CID005748312
DrugPCB 66

RYR1 RYR2 RYR3 PCBP2

5.46e-07111484CID000036185
DrugPCB74

RYR1 RYR2 RYR3

1.07e-0641483CID000036218
Drug148504-47-6

RYR1 RYR2 RYR3

1.07e-0641483CID006444275
DrugSC 38249

RYR1 RYR2 RYR3

1.07e-0641483CID000134834
DrugAC1L1U7A

RYR1 RYR2 RYR3

1.07e-0641483CID000035682
Drugmethylcoumarin

RYR1 RYR2 RYR3 MORF4L1

4.89e-06181484CID000007092
Drugchloro-m-cresol

RYR1 RYR2 RYR3

5.31e-0661483CID000012008
DrugMBED

RYR1 RYR2 RYR3

5.31e-0661483CID000129958
DrugAC1O528X

RYR1 RYR2 RYR3

5.31e-0661483CID006475857
DrugNSC114784

RYR1 RYR2 RYR3

5.31e-0661483CID000419425
DrugTrifluridine [70-00-8]; Down 200; 13.6uM; MCF7; HT_HG-U133A

KRT24 EIF4A1 MKI67 KIF14 LRP6 CDK5RAP2 PCBP2 CCS PRRC2B

5.42e-0619514893559_DN
DrugChlorthalidone [77-36-1]; Up 200; 11.8uM; MCF7; HT_HG-U133A

PSD3 RYR2 RPL23 JAK2 THBS4 LNPEP CDK5RAP2 UTRN ALDH7A1

6.14e-0619814896800_UP
DrugChlorpheniramine maleate [113-92-8]; Down 200; 10.2uM; MCF7; HT_HG-U133A

SUN1 PSD3 CUL7 CDC14A RYR2 PPM1A CLCN6 CEP250 LRP6

6.14e-0619814892217_DN
DrugPhenindione [83-12-5]; Down 200; 18uM; HL60; HG-U133A

ARHGAP10 WRN FOCAD RPL23 ORC2 SLC25A12 SBNO1 MKI67 PARP12

6.39e-0619914891718_DN
Drug2,2',3,5',6-pentachlorobiphenyl

WNT2 CAMK1 RYR1 RYR2

7.66e-06201484ctd:C032904
Drug[[(2R,3S,4R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [(2R,3S,4R,5R)-3,4,5-trihydroxyoxolan-2-yl]methyl hydrogen phosphate

RYR1 RYR2 RYR3

9.24e-0671483CID009547999
DrugAzumoleno

RYR1 RYR2 RYR3

9.24e-0671483CID000056259
DrugBr2BAPTA

RYR1 RYR2 RYR3

9.24e-0671483CID003081001
Drugts M

RYR1 RYR2 PPM1A RYR3 ALDH7A1

1.48e-05481485CID000428025
DrugT0702

RYR1 RYR2 RYR3 SLC22A6

1.95e-05251484CID000005908
DrugPCB 95

RYR1 RYR2 RYR3

3.12e-05101483CID000038012
Drugcreatine

SLC1A3 RYR1 RYR2 RYR3 PTPN2 SLC22A6 IFT122 CCS

3.95e-051931488CID000000586
DrugLOPAC

RYR1 RYR2 RYR3 SCN2A

4.12e-05301484CID000062696
Drugcyclic d(ApAp

RYR1 ALDH7A1

4.20e-0521482CID000188955
Drug5'-adenylyl (beta,gamma-methylene)diphosphonate

RYR1 RYR3

4.20e-0521482ctd:C005147
DrugR 478

RYR1 RYR2 RYR3

4.27e-05111483CID000084223
Drug8-amino-cADPR

RYR1 RYR2 RYR3

4.27e-05111483CID003081323
Drug(R) -Naproxen sodium salt [26159-34-2]; Down 200; 15.8uM; PC3; HT_HG-U133A

SUN1 BLOC1S1 CUL7 CUL5 RPL23 AKAP9 EIF4A1 PCBP2

4.57e-0519714887146_DN
DrugM-HN

RYR1 RYR2 RYR3 ALDH7A1

4.71e-05311484CID000015450
DrugVigabatrin [60643-86-9]; Down 200; 31uM; PC3; HT_HG-U133A

B3GAT3 LRP6 CDK5RAP2 IFT122 PCBP2 UTRN ALDH7A1 PRRC2B

4.73e-0519814886314_DN
Drug6-methylpurine-2'-deoxyriboside

ABCB5 ABCC6 SLC22A6 ABCB11 ABCG8

4.81e-05611485CID000097184
Drug17beta-estradiol glucuronide

ABCB5 ABCC6 SLC22A6 ABCB11

5.35e-05321484CID000066424
DrugRyanodine

RYR1 RYR2 RYR3

5.67e-05121483ctd:D012433
DrugtBuBHQ

RYR1 RYR2 RYR3 DPP9 ALDH7A1

8.72e-05691485CID000002374
DrugDigocin

ABCB5 RYR2 ARHGAP4 PTPN2 SLC22A6

9.34e-05701485CID000003062
Drugmag-fura-2

RYR1 RYR2 RYR3 MORF4L1

9.58e-05371484CID000123839
Drug1,2-dichlorohexafluorocyclobutane

RYR1 RYR2 RYR3 SCN2A

9.58e-05371484CID000009643
Drugsulfate

SUMF2 VPS4A WRN FAHD2A CASP7 SRP54 ITIH4 B3GAT3 JAK2 ARHGAP4 SLC22A6 THBS4 EIF4A2 AFG3L2 UGDH ABCB11 ROCK1 ALDH5A1 MARCO CCS EPHA5

9.62e-05129214821CID000001117
DrugFPL 64176

RYR1 RYR2 RYR3

1.16e-04151483CID000003423
DrugGvapspat amide

RYR1 RYR2 RYR3

1.16e-04151483CID000125015
Drug1,1'-diheptyl-4,4'-bipyridinium

RYR1 RYR3

1.25e-0431482CID000080262
Drugflubendiamide

RYR1 RYR3

1.25e-0431482CID011193251
Drugphenobarbital

CYP2F1 ABCB5 ABCC6 B3GAT3 PTPN2 UGDH ABCB11 PCBP2 ALDH5A1 ALDH7A1

1.27e-0436014810CID000004763
Diseasecongenital myopathy 1A (implicated_via_orthology)

RYR1 RYR2 RYR3

1.21e-0731473DOID:3529 (implicated_via_orthology)
Diseasemalignant hyperthermia (implicated_via_orthology)

RYR1 RYR2 RYR3

1.21e-0731473DOID:8545 (implicated_via_orthology)
DiseaseConventional (Clear Cell) Renal Cell Carcinoma

DNHD1 CUL7 RYR1 FMN2 TAGLN2 RIOK2

1.02e-041481476C0279702
Diseasefibrinogen measurement, coronary artery disease

TDRD15 MIA3 RAPGEF6 SWAP70 MORF4L1 ABCG8

1.26e-041541476EFO_0001645, EFO_0004623
DiseaseX-linked mental retardation with cerebellar hypoplasia and distinctive facial appearance (implicated_via_orthology)

ARHGAP42 ARHGAP10

1.47e-0441472DOID:0080311 (implicated_via_orthology)
Diseasetotal lipids in medium VLDL

TDRD15 ITIH3 ITIH4 ABCG8

1.54e-04541474EFO_0022153
Diseasecoronary artery disease

ARHGAP42 TTC39B TDRD15 MIA3 SWAP70 PSD3 ITIH4 PPM1A LNPEP KIAA1217 MORF4L1 FMN2 C1R ALDH5A1 ABCG8 PARP12

3.15e-04119414716EFO_0001645
DiseaseSarcomatoid Renal Cell Carcinoma

DNHD1 CUL7 RYR1 FMN2 TAGLN2

4.64e-041281475C1266043
DiseaseChromophobe Renal Cell Carcinoma

DNHD1 CUL7 RYR1 FMN2 TAGLN2

4.64e-041281475C1266042
DiseaseCollecting Duct Carcinoma of the Kidney

DNHD1 CUL7 RYR1 FMN2 TAGLN2

4.64e-041281475C1266044
DiseasePapillary Renal Cell Carcinoma

DNHD1 CUL7 RYR1 FMN2 TAGLN2

4.64e-041281475C1306837
DiseaseRenal Cell Carcinoma

DNHD1 CUL7 RYR1 FMN2 TAGLN2

4.64e-041281475C0007134
Diseaseosteoporosis

CDC42SE1 SCG2 FAM3C ALDH7A1

4.93e-04731474EFO_0003882
Diseasecholesteryl ester 24:4 measurement

TTC39B ABCG8

5.09e-0471472EFO_0021447
Diseasepolyunsaturated fatty acid measurement

TTC39B TDRD15 PSD3 ABCB11 ABCG8

5.15e-041311475EFO_0010733
DiseaseCholestasis of pregnancy

ABCB11 ABCG8

6.77e-0481472C0268318
Diseasecystic fibrosis (implicated_via_orthology)

ABCB5 ABCB11

8.67e-0491472DOID:1485 (implicated_via_orthology)
Diseaselipoprotein measurement, phospholipid measurement

TTC39B TDRD15 ABCB11 ABCG8

8.75e-04851474EFO_0004639, EFO_0004732
Diseasevery low density lipoprotein cholesterol measurement, cholesterol:total lipids ratio

TTC39B TDRD15 USP24 PSD3 TYW1B ABCG8

8.88e-042221476EFO_0008317, EFO_0020943
Diseasetriglycerides:total lipids ratio, low density lipoprotein cholesterol measurement

TTC39B TDRD15 PSD3 TYW1B ABCG8

9.50e-041501475EFO_0004611, EFO_0020947
Diseasetriglycerides:total lipids ratio, very low density lipoprotein cholesterol measurement

TTC39B TDRD15 USP24 PSD3 TYW1B ABCG8

9.52e-042251476EFO_0008317, EFO_0020947
Diseasetriglyceride measurement, low density lipoprotein cholesterol measurement

TTC39B TDRD15 PSD3 TYW1B ABCB11

1.49e-031661475EFO_0004530, EFO_0004611
Diseaselow density lipoprotein cholesterol measurement, alcohol consumption measurement

TDRD15 PSD3 ABCB11 ABCG8

1.54e-03991474EFO_0004611, EFO_0007878
Diseaseresponse to angiotensin-converting enzyme inhibitor, Cough

ABCB5 WRN PKD1L2

1.57e-03461473EFO_0005325, HP_0012735
DiseaseOligospermia

CDC14A PIWIL3

1.57e-03121472C0028960
Diseaselow density lipoprotein cholesterol measurement, alcohol drinking

TDRD15 PSD3 ABCB11 ABCG8

1.72e-031021474EFO_0004329, EFO_0004611
Diseaseextracellular matrix protein 1 measurement

MIA3 CDC42SE1

1.85e-03131472EFO_0008126
DiseaseMental Retardation, X-Linked Nonsyndromic

HUWE1 ARHGEF6

1.85e-03131472C3501611
Diseasecholesteryl ester measurement

TTC39B TDRD15 PSD3 ITIH3 ITIH4 ABCG8

1.87e-032571476EFO_0010351
Diseasecholesteryl esters to total lipids in small VLDL percentage

TTC39B TDRD15 ABCG8

1.89e-03491473EFO_0022256
Diseasemyocardial infarction

ARHGAP42 TDRD15 MIA3 SASH1 SWAP70 MORF4L1 PARP12

1.92e-033501477EFO_0000612
Diseasecoronary artery calcification

DMXL2 FSTL5 PSD3 FSIP2 MORF4L1 LRP6 CDH12 ALDH7A1

1.94e-034501478EFO_0004723
Diseasevery low density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio

TTC39B TDRD15 USP24 PSD3 TYW1B ABCG8

2.14e-032641476EFO_0008317, EFO_0020944
Diseaseheel bone mineral density, urate measurement

FSTL5 WRN FKBP9 PSD3 UTRN

2.23e-031821475EFO_0004531, EFO_0009270
Diseaseinsulin measurement

SASH1 PSD3 ITIH3 ITIH4 ABCB11 CHD6

2.27e-032671476EFO_0004467
Diseasecoronary artery disease, factor VII measurement

TDRD15 MIA3 MORF4L1 ABCG8

2.34e-031111474EFO_0001645, EFO_0004619
Diseasefactor VIII measurement, coronary artery disease

TDRD15 MIA3 MORF4L1 ABCG8

2.50e-031131474EFO_0001645, EFO_0004630
Diseasefactor XI measurement, coronary artery disease

TDRD15 MIA3 MORF4L1 ABCG8

2.66e-031151474EFO_0001645, EFO_0004694
DiseaseColorectal Carcinoma

CCDC9B ABCB5 FSTL5 WRN CDC14A ABCC6 AKAP9 MKI67 ABCB11 UQCRC2

2.80e-0370214710C0009402
Diseasevon Willebrand factor measurement, coronary artery disease

TDRD15 MIA3 MORF4L1 ABCG8

2.92e-031181474EFO_0001645, EFO_0004629
Diseasespine bone mineral density

PCBP3 WNT5B FAM3C MARCO

3.01e-031191474EFO_0007701
Diseaseomega-6 polyunsaturated fatty acid measurement

TTC39B TDRD15 PSD3 ABCB11 ABCG8

3.13e-031971475EFO_0005680
Diseaseresponse to phenylephrine

IQGAP2 FAM3C

3.19e-03171472EFO_0010152
Diseasevery low density lipoprotein cholesterol measurement, phospholipids:total lipids ratio

TTC39B TDRD15 USP24 PSD3 TYW1B ABCG8

3.46e-032911476EFO_0008317, EFO_0020946
Diseasecoronary artery disease, plasminogen activator inhibitor 1 measurement

TDRD15 MORF4L1 ABCG8

3.87e-03631473EFO_0001645, EFO_0004792
Diseaseurate measurement, bone density

ABCB5 FSTL5 PSD3 FSIP2 KIF14 UGGT2 UTRN CDH12 PRRC2B

3.96e-036191479EFO_0003923, EFO_0004531
DiseaseCholecystitis

TTC39B ABCG8

3.99e-03191472HP_0001082
Diseaseresponse to vaccine, cytokine measurement

PCBP3 ARHGAP10 ITIH3 ITIH4

4.25e-031311474EFO_0004645, EFO_0004873
Diseaselow density lipoprotein cholesterol measurement, physical activity

TDRD15 ABCB11 ABCG8

4.41e-03661473EFO_0003940, EFO_0004611
Diseaseexercise test

WRN RYR2

4.42e-03201472EFO_0004328
Diseasefree cholesterol measurement, very low density lipoprotein cholesterol measurement

TDRD15 PSD3 ITIH3 TYW1B ABCG8

4.54e-032151475EFO_0008317, EFO_0008591

Protein segments in the cluster

PeptideGeneStartEntry
TGKGVEQELQGNSIM

UMODL1

626

Q5DID0
QQQGDVKTGAMKNLL

URB2

261

Q14146
MKQEEQLQRQGRGSD

B3GAT3

316

O94766
LEGQRLQGIMQEFQK

AKAP9

3431

Q99996
IQMKQQQRNRLGSGG

CCDC61

361

Q9Y6R9
GEDIKNLGNVIFMSQ

ARHGEF6

441

Q15052
LMSNGIITFKNEVGQ

CUL5

576

Q93034
TGAVQEQMRSKGNRD

CDC42SE1

56

Q9NRR8
IGMVENFNQALKEIG

BLOC1S1

106

P78537
TQVGKQVGLMVQERF

ALDH7A1

276

P49419
IVQFGMNEKVGQISF

AFG3L2

661

Q9Y4W6
GNLSKTQNMERFGED

CDC14A

366

Q9UNH5
KGAQMSGGQKQRIAI

ABCB5

521

Q2M3G0
KKNDGQFTVIQLVGM

EPHA5

766

P54756
GGQMSGGQKQRVAIA

ABCB11

556

O95342
LGIQNLSFKVRSGQM

ABCG8

86

Q9H221
KQSIFRNIGAGVMQI

DMXL2

2986

Q8TDJ6
VDGKNVDMAGFIANN

CELSR1

1626

Q9NYQ6
NNMGQKRQTEESIGI

DNHD1

2066

Q96M86
RQRIIGGQKAKMGNF

C1R

461

P00736
MEDVFQNLTQDGKGI

CAPN14

656

A8MX76
FLNGKSVGVEMNTQN

CDK5RAP2

1316

Q96SN8
GLVKATGRNMEQFQV

ITIH4

116

Q14624
TRQQGEKFAQQITGM

RAB12

166

Q6IQ22
KQVAEQFLNMRGGLG

UQCRC2

231

P22695
VEFGARMVNIDGKQI

RAB2B

41

Q8WUD1
QFSIQILRNFGMGKR

CYP2F1

126

P24903
DDIVNSLQKMQNKGG

FAM81A

56

Q8TBF8
FLQQLGKGNFGSVEM

JAK2

851

O60674
MGKQAEEQQKFGERV

PTPN23

256

Q9H3S7
NKIMTEKYNGNRIGL

PTPN2

306

P17706
SKNQQDDGKMFIGGL

HNRNPDL

141

O14979
QKANQEQYAEGKMRG

MORF4L1

116

Q9UBU8
EGNAQLDKMGFTIIR

ARHGAP10

386

A1A4S6
VILAIGNFMNKGQRG

DAAM2

801

Q86T65
VLMSGVKNNVGRGIN

FAM3C

91

Q92520
NVLVTQRKGNFFMGG

DAZAP2

146

Q15038
VKMTLNVGGETENNG

KIF14

141

Q15058
MFNGIISIRNKNGEE

IFT122

151

Q9HBG6
ERESQGQGEMFLQKA

GPR179

2146

Q6PRD1
EGGLRAQMDQVKSQG

MTMR8

591

Q96EF0
RQMIGEFLGNRQKQF

IQSEC1

571

Q6DN90
ESKNMVVNGRRNGGK

KMT5B

6

Q4FZB7
QDNGINQKRDGMVSK

FSIP2

391

Q5CZC0
EEQAQKQSGMEQGRL

CCDC9B

366

Q6ZUT6
GGTNVRAEVQKLQME

EIF4A1

136

P60842
NGFMQQKGREQKIRL

PCLO

1981

Q9Y6V0
KNMFTNQDRNGDGKV

FKBP9P1

111

Q75LS8
GMDFIGRDALLQQKQ

PDPR

746

Q8NCN5
TNGAVFVNGKEMTNQ

CRLF3

356

Q8IUI8
QQIQGSRIGGAQEME

CUL7

1226

Q14999
FSGGEKQTMQNLNDR

KRT24

136

Q2M2I5
ERGLLSGNEKVTMQN

KRT25

71

Q7Z3Z0
QNMIRKAQEDGSQGF

LRP6

986

O75581
FIVGEMKNLSQDVNG

LNPEP

361

Q9UIQ6
GEVVQSGNTNQMVFK

FAHD2A

241

Q96GK7
VLMQNQKGKGEAGNS

MKI67

3181

P46013
FAALEGMNGIQKFQI

HUWE1

4311

Q7Z6Z7
QMSGAQIKIANATEG

PCBP3

321

P57721
MEQKQLQKRFGGFTG

PNOC

121

Q13519
GDTQQTQAMAKVALG

PKD1L2

851

Q7Z442
NQESSRVKGFMIQDG

FSTL5

46

Q8N475
QGAKINEIRQMSGAQ

PCBP2

306

Q15366
GQMQKQNGGKAVDER

PARP12

546

Q9H0J9
MRKLQLGTSQEGQGQ

CAMK1

316

Q14012
NAGVIVNNKGEMKGS

RPL23

101

P62829
MFTNQDRNGDGKVTA

FKBP9

541

O95302
VTENRGNEKEFMKGN

CLCN6

636

P51797
NEVNKNEGMSGLFGL

CPLANE1

1666

Q9H799
EQYQVVIQAKDMGGQ

CDH10

231

Q9Y6N8
NRKGGTNGVQQLSKM

CHD6

936

Q8TD26
GLRFEGALKNQMGQV

DPP9

686

Q86TI2
VIGNMKEQGQALREF

SLC1A3

256

P43003
ASMKEGKQGIQRNQE

POLQ

561

O75417
GRSEVFLKMGKNNQS

NDUFAF1

146

Q9Y375
TQRQLMQERAEEGKG

CEP250

1701

Q9BV73
RQAVLKGMGSGQLQN

CCS

71

O14618
IIINNKNFDKVTGMG

CASP7

71

P55210
IGGTNVRNEMQKLQA

EIF4A2

136

Q14240
NFTQNPGMFRIKGEQ

MARCO

136

Q9UEW3
EQYQVLIQAKDMGGQ

CDH12

231

P55289
LFGLGMNQDKGSRKQ

FMN2

1271

Q9NZ56
NIVQGRRMVKANSQG

PIWIL3

476

Q7Z3Z3
NQQLSEMAAGKGRGR

PRDM13

526

Q9H4Q3
MAFNDLLQQVGGVGR

SLC22A6

1

Q4U2R8
NNIGKFLNRILGMEV

SBNO1

1101

A3KN83
AGREVEKVFNGLSNM

SBSN

61

Q6UWP8
FERQNKAEGLGMVNE

RYR1

3846

P21817
DGTVINRQNGEKVMA

RYR1

3861

P21817
NAFERQNKAEGLGMV

RYR2

3806

Q92736
GEMKVEQLFQEFGNR

DYRK3

81

O43781
KAIENIRQMGGNTNT

COL6A6

501

A6NMZ7
MQALKEGQGGEKNIQ

FOCAD

111

Q5VW36
RKMQLSGNGLEEQAA

LRRC74B

166

Q6ZQY2
DSQMLRGEKSQQIIG

ORC2

396

Q13416
GNRQKMVKALGNSEE

UTRN

2511

P46939
KLGNGQATSMVQLQG

SUMF2

21

Q8NBJ7
GLKRGDQIMEVNGQN

RAPGEF6

571

Q8TEU7
AVIDNGRGMTSKQLN

SMCHD1

181

A6NHR9
AEAMKKNLRVGNGFE

ALDH5A1

361

P51649
QNVIMFVGLQGSGKT

SRP54

101

P61011
MERGLFQTGQKGLND

GINS3

171

Q9BRX5
KNVIGLQMGTNRGAS

TAGLN2

171

P37802
FVDFGNKQLVGENML

TDRD15

1046

B5MCY1
NGEVGGDRNEKMKNQ

MIA3

1436

Q5JRA6
IGEQGMNLSGGQKQR

ABCC6

746

O95255
YRIGGVNSKVQKLMN

ARHGAP42

416

A6NI28
KGGEMEILNNTDNQG

IQGAP2

856

Q13576
GKLGIANAQMDFQVE

ITIH3

711

Q06033
QGNTVQLQGMRKGAA

HEPH

661

Q9BQS7
EQINDEMKRSGQLGI

SCG2

276

P13521
SADRRQMQEQGKGNL

KIAA1217

16

Q5T5P2
SGQMVGQKVGNEIDR

ST6GALNAC3

86

Q8NDV1
TIAFGMGINKADIRQ

WRN

821

Q14191
EKERIQNAGGSVMIQ

PPM1B

176

O75688
NFSGRIEGIQKAIMD

SPATA9

16

Q9BWV2
NQRLFGGDMEKFIQS

ARHGAP4

501

P98171
RKMTERGDELQQAGQ

SPTBN5

1406

Q9NRC6
QTKVIDMGGRQIFNN

ST18

341

O60284
KTRMQNQRGSGSVVG

SLC25A12

351

O75746
MVQGVGISFAKSNKQ

THBS4

361

P35443
VATAIGMDQRIGNKF

UGDH

251

O60701
GFLKNQIFSGIQMTR

ZNF561

96

Q8N587
RKYNGAIQVVMNQDG

WNT2

236

P09544
MAQQRNGVIFQEGGE

THOC2

746

Q8NI27
FVQDENMINFIKGGL

TTC39B

251

Q5VTQ0
ERENVFGKTLNLGMN

ZNF334

111

Q9HCZ1
DAGMIGNQVNRKVLN

NAA35

71

Q5VZE5
GKRERKQSFMGNSGN

RNF112

16

Q9ULX5
EKERIQNAGGSVMIQ

PPM1A

171

P35813
NAFERQNKAEGLGMV

RYR3

3696

Q15413
SGQQKNIGMVEIRGN

SNRPGP15

51

A8MWD9
VQNMEGDKSQQLGRV

SYT15B

421

X6R8R1
NNLQIAVGRMQKGID

SCN2A

1001

Q99250
AKGSEEQGRVLMNLQ

WNT5B

186

Q9H1J7
RAGEQGEAMKQFDLN

PRRC2B

1521

Q5JSZ5
NQKGIMRQTSKGEDV

SASH1

161

O94885
RQVVESVGNQMGVGK

RIOK2

91

Q9BVS4
AKAGQEFARNNLMGD

POGLUT2

436

Q6UW63
AQLTKQYRGNEGQMR

ROCK1

826

Q13464
KMGRDQIFKNTFQGI

USP24

1791

Q9UPU5
DQRLAEQKMAQTGRG

ZNF608

1111

Q9ULD9
LIGNGQFSKGMDRQT

SWAP70

181

Q9UH65
NNMGSQGIQETGKTR

ZBTB10

561

Q96DT7
QKLQARVDQMEGGAA

SUN1

391

O94901
KEQQEEKSGLFRNMG

TYW1

331

Q9NV66
KIKGIVENMGINANN

UGGT2

906

Q9NYU1
KGFNDEGIFMQHQRI

ZNF629

576

Q9UEG4
QAEISQIMNNGRKGA

PSD3

226

Q9NYI0
SKIVGDLAQFMVQNG

PC

911

P11498
EQQEEKSGLFRNMGR

TYW1B

286

Q6NUM6
RIKTEFLVQMQGVGN

VPS4A

246

Q9UN37