Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	gated channel activity	KCNMB2 CACNA1B TRPV1 KCNH7 TRPM5 ANO6 CACNA1H TMC5 KCNT1	4.90e-06	334	76	9	GO:0022836
GeneOntologyMolecularFunction	transporter activity	KCNMB2 CACNA1B SLC38A2 TRPV1 SLC22A25 KCNH7 TRPM5 ANO6 SLC35B4 TMEM184C ATP11C CACNA1H ABCC12 SERINC5 TMC5 ATP2B3 KCNT1	5.31e-06	1289	76	17	GO:0005215
GeneOntologyMolecularFunction	monoatomic ion-gated channel activity	KCNMB2 TRPM5 ANO6 KCNT1	5.64e-06	31	76	4	GO:0022839
GeneOntologyMolecularFunction	ligand-gated monoatomic cation channel activity	KCNMB2 TRPV1 KCNH7 TRPM5 ANO6 KCNT1	1.56e-05	140	76	6	GO:0099094
GeneOntologyMolecularFunction	transmembrane transporter activity	KCNMB2 CACNA1B SLC38A2 TRPV1 SLC22A25 KCNH7 TRPM5 ANO6 SLC35B4 CACNA1H ABCC12 SERINC5 TMC5 ATP2B3 KCNT1	3.22e-05	1180	76	15	GO:0022857
GeneOntologyMolecularFunction	monoatomic cation channel activity	KCNMB2 CACNA1B TRPV1 KCNH7 TRPM5 ANO6 CACNA1H KCNT1	4.77e-05	343	76	8	GO:0005261
GeneOntologyMolecularFunction	monoatomic ion channel activity	KCNMB2 CACNA1B TRPV1 KCNH7 TRPM5 ANO6 CACNA1H TMC5 KCNT1	6.03e-05	459	76	9	GO:0005216
GeneOntologyMolecularFunction	metal ion transmembrane transporter activity	KCNMB2 CACNA1B SLC38A2 TRPV1 KCNH7 TRPM5 CACNA1H ATP2B3 KCNT1	6.67e-05	465	76	9	GO:0046873
GeneOntologyMolecularFunction	voltage-gated monoatomic ion channel activity	CACNA1B TRPV1 KCNH7 ANO6 CACNA1H KCNT1	6.80e-05	182	76	6	GO:0005244
GeneOntologyMolecularFunction	voltage-gated channel activity	CACNA1B TRPV1 KCNH7 ANO6 CACNA1H KCNT1	7.23e-05	184	76	6	GO:0022832
GeneOntologyMolecularFunction	ligand-gated monoatomic ion channel activity	KCNMB2 TRPV1 KCNH7 TRPM5 ANO6 KCNT1	9.40e-05	193	76	6	GO:0015276
GeneOntologyMolecularFunction	ligand-gated channel activity	KCNMB2 TRPV1 KCNH7 TRPM5 ANO6 KCNT1	1.05e-04	197	76	6	GO:0022834
GeneOntologyMolecularFunction	alkylglycerophosphoethanolamine phosphodiesterase activity	GNA11 GNAQ	1.42e-04	5	76	2	GO:0047391
GeneOntologyMolecularFunction	calcium-activated cation channel activity	KCNMB2 TRPM5 ANO6	1.45e-04	27	76	3	GO:0005227
GeneOntologyMolecularFunction	channel activity	KCNMB2 CACNA1B TRPV1 KCNH7 TRPM5 ANO6 CACNA1H TMC5 KCNT1	1.67e-04	525	76	9	GO:0015267
GeneOntologyMolecularFunction	passive transmembrane transporter activity	KCNMB2 CACNA1B TRPV1 KCNH7 TRPM5 ANO6 CACNA1H TMC5 KCNT1	1.69e-04	526	76	9	GO:0022803
GeneOntologyMolecularFunction	monoatomic ion transmembrane transporter activity	KCNMB2 CACNA1B SLC38A2 TRPV1 KCNH7 TRPM5 ANO6 CACNA1H TMC5 ATP2B3 KCNT1	1.96e-04	793	76	11	GO:0015075
GeneOntologyMolecularFunction	monoatomic cation transmembrane transporter activity	KCNMB2 CACNA1B SLC38A2 TRPV1 KCNH7 TRPM5 ANO6 CACNA1H ATP2B3 KCNT1	2.04e-04	664	76	10	GO:0008324
GeneOntologyMolecularFunction	calcium ion transmembrane transporter activity	CACNA1B TRPV1 TRPM5 CACNA1H ATP2B3	2.78e-04	151	76	5	GO:0015085
GeneOntologyMolecularFunction	voltage-gated monoatomic cation channel activity	CACNA1B TRPV1 KCNH7 CACNA1H KCNT1	2.86e-04	152	76	5	GO:0022843
GeneOntologyMolecularFunction	steroid hormone binding	SULT2B1 GPER1	2.97e-04	7	76	2	GO:1990239
GeneOntologyMolecularFunction	L-serine transmembrane transporter activity	SLC38A2 SERINC5	5.06e-04	9	76	2	GO:0015194
GeneOntologyMolecularFunction	inorganic molecular entity transmembrane transporter activity	KCNMB2 CACNA1B SLC38A2 TRPV1 KCNH7 TRPM5 ANO6 CACNA1H ATP2B3 KCNT1	5.81e-04	758	76	10	GO:0015318
GeneOntologyMolecularFunction	inorganic cation transmembrane transporter activity	KCNMB2 CACNA1B SLC38A2 TRPV1 KCNH7 TRPM5 CACNA1H ATP2B3 KCNT1	6.12e-04	627	76	9	GO:0022890
GeneOntologyMolecularFunction	voltage-gated calcium channel activity	CACNA1B TRPV1 CACNA1H	7.15e-04	46	76	3	GO:0005245
GeneOntologyMolecularFunction	signal sequence binding	AP2M1 TNPO2 NUP58	9.68e-04	51	76	3	GO:0005048
GeneOntologyMolecularFunction	high voltage-gated calcium channel activity	CACNA1B CACNA1H	1.26e-03	14	76	2	GO:0008331
GeneOntologyMolecularFunction	potassium channel activity	KCNMB2 KCNH7 TRPM5 KCNT1	1.45e-03	128	76	4	GO:0005267
GeneOntologyMolecularFunction	calcium channel activity	CACNA1B TRPV1 TRPM5 CACNA1H	1.49e-03	129	76	4	GO:0005262
GeneOntologyMolecularFunction	nuclear import signal receptor activity	TNPO2 TNPO3	2.60e-03	20	76	2	GO:0061608
GeneOntologyMolecularFunction	ion channel regulator activity	KCNMB2 TRPV1 RASA1 GRM3	3.40e-03	162	76	4	GO:0099106
GeneOntologyMolecularFunction	potassium ion transmembrane transporter activity	KCNMB2 KCNH7 TRPM5 KCNT1	3.79e-03	167	76	4	GO:0015079
GeneOntologyMolecularFunction	G-protein beta/gamma-subunit complex binding	GNA11 GNAQ	4.05e-03	25	76	2	GO:0031683
GeneOntologyMolecularFunction	channel regulator activity	KCNMB2 TRPV1 RASA1 GRM3	4.39e-03	174	76	4	GO:0016247
GeneOntologyMolecularFunction	transporter regulator activity	KCNMB2 TRPV1 RASA1 GRM3	4.66e-03	177	76	4	GO:0141108
GeneOntologyMolecularFunction	nuclear localization sequence binding	TNPO2 NUP58	4.72e-03	27	76	2	GO:0008139
GeneOntologyMolecularFunction	scaffold protein binding	NLGN3 CACNA1H GRM3	5.38e-03	93	76	3	GO:0097110
GeneOntologyBiologicalProcess	regulation of membrane potential	KCNMB2 ADCY10 NLGN3 RELN TRPV1 KCNH7 GPER1 ANO6 GNA11 CACNA1H GNAQ KCNT1	7.70e-07	559	75	12	GO:0042391
GeneOntologyBiologicalProcess	monoatomic ion transport	KCNMB2 CACNA1B SLC38A2 SLC35G1 NLGN3 RELN TRPV1 SLC22A25 KCNH7 TRPM5 GPER1 ANO6 ATP11C CACNA1H GNAQ TMC5 ATP2B3 KCNT1	1.49e-06	1374	75	18	GO:0006811
GeneOntologyBiologicalProcess	monoatomic ion transmembrane transport	KCNMB2 CACNA1B SLC38A2 SLC35G1 NLGN3 RELN TRPV1 KCNH7 TRPM5 GPER1 ANO6 ATP11C CACNA1H TMC5 ATP2B3 KCNT1	2.00e-06	1115	75	16	GO:0034220
GeneOntologyBiologicalProcess	circadian rhythm	NLGN3 KCNH7 USP7 GNA11 GNAQ ANKFN1 GFPT1	3.30e-05	248	75	7	GO:0007623
GeneOntologyBiologicalProcess	metal ion transport	KCNMB2 CACNA1B SLC38A2 SLC35G1 TRPV1 KCNH7 TRPM5 GPER1 ANO6 CACNA1H GNAQ ATP2B3 KCNT1	5.84e-05	1000	75	13	GO:0030001
GeneOntologyBiologicalProcess	glutamate receptor signaling pathway	NLGN3 GNA11 GNAQ GRM3	6.31e-05	59	75	4	GO:0007215
GeneOntologyBiologicalProcess	calcium ion transmembrane transport	CACNA1B SLC35G1 TRPV1 TRPM5 GPER1 ANO6 CACNA1H ATP2B3	8.80e-05	392	75	8	GO:0070588
GeneOntologyBiologicalProcess	inorganic cation transmembrane transport	KCNMB2 CACNA1B SLC38A2 SLC35G1 TRPV1 KCNH7 TRPM5 GPER1 ANO6 CACNA1H ATP2B3 KCNT1	1.15e-04	922	75	12	GO:0098662
GeneOntologyBiologicalProcess	positive regulation of AMPA receptor activity	NLGN3 RELN	1.30e-04	5	75	2	GO:2000969
GeneOntologyBiologicalProcess	monoatomic cation transmembrane transport	KCNMB2 CACNA1B SLC38A2 SLC35G1 TRPV1 KCNH7 TRPM5 GPER1 ANO6 CACNA1H ATP2B3 KCNT1	1.41e-04	942	75	12	GO:0098655
GeneOntologyBiologicalProcess	monoatomic cation transport	KCNMB2 CACNA1B SLC38A2 SLC35G1 TRPV1 KCNH7 TRPM5 GPER1 ANO6 CACNA1H GNAQ ATP2B3 KCNT1	2.50e-04	1157	75	13	GO:0006812
GeneOntologyBiologicalProcess	regulation of melanocyte differentiation	GNA11 GNAQ	2.71e-04	7	75	2	GO:0045634
GeneOntologyBiologicalProcess	inorganic ion transmembrane transport	KCNMB2 CACNA1B SLC38A2 SLC35G1 TRPV1 KCNH7 TRPM5 GPER1 ANO6 CACNA1H ATP2B3 KCNT1	2.86e-04	1017	75	12	GO:0098660
GeneOntologyBiologicalProcess	circulatory system process	KCNMB2 ADCY10 CACNA1B SLC38A2 TRPV1 GPER1 GNA11 CACNA1H GNAQ ATP2B3	3.11e-04	733	75	10	GO:0003013
GeneOntologyBiologicalProcess	regulation of system process	KCNMB2 ADCY10 CACNA1B NLGN3 RELN TRPV1 GPER1 CACNA1H GRM3 ATP2B3	3.14e-04	734	75	10	GO:0044057
GeneOntologyBiologicalProcess	rhythmic process	NLGN3 KCNH7 USP7 GNA11 GNAQ ANKFN1 GFPT1	3.34e-04	360	75	7	GO:0048511
GeneOntologyBiologicalProcess	regulation of synaptic transmission, glutamatergic	SLC38A2 NLGN3 RELN GRM3	3.54e-04	92	75	4	GO:0051966
GeneOntologyBiologicalProcess	phospholipase C-activating dopamine receptor signaling pathway	GNA11 GNAQ	4.62e-04	9	75	2	GO:0060158
GeneOntologyBiologicalProcess	regulation of pigment cell differentiation	GNA11 GNAQ	4.62e-04	9	75	2	GO:0050932
GeneOntologyBiologicalProcess	L-serine transport	SLC38A2 SERINC5	4.62e-04	9	75	2	GO:0015825
GeneOntologyBiologicalProcess	potassium ion transport	KCNMB2 KCNH7 TRPM5 ANO6 GNAQ KCNT1	4.68e-04	272	75	6	GO:0006813
GeneOntologyBiologicalProcess	regulation of postsynaptic membrane potential	NLGN3 RELN TRPV1 ANO6 KCNT1	5.04e-04	180	75	5	GO:0060078
GeneOntologyBiologicalProcess	calcium ion transport	CACNA1B SLC35G1 TRPV1 TRPM5 GPER1 ANO6 CACNA1H ATP2B3	5.15e-04	509	75	8	GO:0006816
GeneOntologyBiologicalProcess	blood circulation	KCNMB2 ADCY10 CACNA1B TRPV1 GPER1 GNA11 CACNA1H GNAQ ATP2B3	5.58e-04	648	75	9	GO:0008015
GeneOntologyCellularComponent	dendrite	ADCY10 CACNA1B SLC38A2 NLGN3 RELN TRPV1 BRINP3 TRPM5 GPER1 DOCK10 CACNA1H GNAQ GRM3	1.19e-05	858	76	13	GO:0030425
GeneOntologyCellularComponent	dendritic tree	ADCY10 CACNA1B SLC38A2 NLGN3 RELN TRPV1 BRINP3 TRPM5 GPER1 DOCK10 CACNA1H GNAQ GRM3	1.22e-05	860	76	13	GO:0097447
GeneOntologyCellularComponent	synaptic membrane	VANGL2 NLGN3 TRPV1 AP2M1 GPER1 ANO6 CACNA1H GRM3 ATP2B3 KCNT1	4.81e-05	583	76	10	GO:0097060
GeneOntologyCellularComponent	cell body	ADCY10 CACNA1B SLC38A2 NLGN3 RELN TRPV1 BRINP3 TRPM5 GPER1 ACTG2 CACNA1H GNAQ	1.24e-04	929	76	12	GO:0044297
GeneOntologyCellularComponent	somatodendritic compartment	ADCY10 CACNA1B SLC38A2 NLGN3 RELN TRPV1 BRINP3 TRPM5 GPER1 DOCK10 CACNA1H GNAQ GRM3	4.46e-04	1228	76	13	GO:0036477
GeneOntologyCellularComponent	postsynaptic membrane	VANGL2 NLGN3 TRPV1 GPER1 CACNA1H GRM3 KCNT1	6.74e-04	405	76	7	GO:0045211
GeneOntologyCellularComponent	transporter complex	KCNMB2 CACNA1B KCNH7 TRPM5 ERGIC3 ANO6 ATP11C CACNA1H	8.56e-04	550	76	8	GO:1990351
GeneOntologyCellularComponent	neuronal cell body	ADCY10 CACNA1B SLC38A2 NLGN3 RELN TRPV1 BRINP3 TRPM5 GPER1 CACNA1H	8.60e-04	835	76	10	GO:0043025
MousePheno	abnormal channel response	KCNMB2 CACNA1B CACNA1H KCNT1	1.07e-05	33	59	4	MP:0003484
MousePheno	impaired ability to fire action potentials	KCNMB2 TRPV1 KCNT1	1.98e-05	13	59	3	MP:0002578
Domain	Gprotein_alpha_Q	GNA11 GNAQ	9.50e-05	4	75	2	IPR000654
Domain	Ion_trans_dom	CACNA1B TRPV1 KCNH7 TRPM5 CACNA1H	9.53e-05	114	75	5	IPR005821
Domain	Ion_trans	CACNA1B TRPV1 KCNH7 TRPM5 CACNA1H	9.53e-05	114	75	5	PF00520
Domain	Serpin_fam	SERPINA3 SERPINB11 NUP58	5.12e-04	39	75	3	IPR000215
Domain	VDCCAlpha1	CACNA1B CACNA1H	7.01e-04	10	75	2	IPR002077
Domain	RasGAP	GAPVD1 RASA1	1.62e-03	15	75	2	PF00616
Domain	RAS_GTPASE_ACTIV_1	GAPVD1 RASA1	1.62e-03	15	75	2	PS00509
Domain	RAS_GTPASE_ACTIV_2	GAPVD1 RASA1	1.62e-03	15	75	2	PS50018
Domain	G-alpha	GNA11 GNAQ	1.84e-03	16	75	2	PF00503
Domain	GproteinA_insert	GNA11 GNAQ	1.84e-03	16	75	2	IPR011025
Domain	-	GAPVD1 RASA1	1.84e-03	16	75	2	1.10.506.10
Domain	-	GNA11 GNAQ	1.84e-03	16	75	2	1.10.400.10
Domain	G_alpha	GNA11 GNAQ	1.84e-03	16	75	2	SM00275
Domain	Gprotein_alpha_su	GNA11 GNAQ	2.08e-03	17	75	2	IPR001019
Domain	RasGAP_dom	GAPVD1 RASA1	2.34e-03	18	75	2	IPR001936
Pubmed	A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse.	CACNA1B KCNH7 ERGIC3 VPS13C MFSD6 MPP7	3.40e-08	85	76	6	23055939
Pubmed	GNAQ and GNA11 mutations occur in 9.5% of mucosal melanoma and are associated with poor prognosis.	GNA11 GNAQ	4.71e-06	2	76	2	27498141
Pubmed	The Role of Mutation Rates of GNAQ or GNA11 in Cases of Uveal Melanoma in Japan.	GNA11 GNAQ	4.71e-06	2	76	2	28248732
Pubmed	Uveal Melanoma: GNAQ and GNA11 Mutations in a Greek Population.	GNA11 GNAQ	4.71e-06	2	76	2	28982892
Pubmed	Mutations in GNA11 in uveal melanoma.	GNA11 GNAQ	4.71e-06	2	76	2	21083380
Pubmed	Activation of Gq/11 in the mouse corpus luteum is required for parturition.	GNA11 GNAQ	4.71e-06	2	76	2	25495873
Pubmed	GNAQ and GNA11 mutations in uveal melanoma.	GNA11 GNAQ	4.71e-06	2	76	2	25304237
Pubmed	Epidermal loss of Gαq confers a migratory and differentiation defect in keratinocytes.	GNA11 GNAQ	4.71e-06	2	76	2	28301547
Pubmed	Forebrain-specific inactivation of Gq/G11 family G proteins results in age-dependent epilepsy and impaired endocannabinoid formation.	GNA11 GNAQ	4.71e-06	2	76	2	16847339
Pubmed	Uveal melanoma driver mutations in GNAQ/11 yield numerous changes in melanocyte biology.	GNA11 GNAQ	4.71e-06	2	76	2	29570931
Pubmed	Muscarinic inhibition of calcium current and M current in Galpha q-deficient mice.	GNA11 GNAQ	4.71e-06	2	76	2	10818132
Pubmed	Endothelial Gαq/11 is required for VEGF-induced vascular permeability and angiogenesis.	GNA11 GNAQ	4.71e-06	2	76	2	26272756
Pubmed	NK2 receptor-mediated detrusor muscle contraction involves Gq/11-dependent activation of voltage-dependent Ca2+ channels and the RhoA-Rho kinase pathway.	GNA11 GNAQ	4.71e-06	2	76	2	31461351
Pubmed	Ultradeep sequencing detects GNAQ and GNA11 mutations in cell-free DNA from plasma of patients with uveal melanoma.	GNA11 GNAQ	4.71e-06	2	76	2	23634288
Pubmed	Distribution of GNAQ and GNA11 Mutation Signatures in Uveal Melanoma Points to a Light Dependent Mutation Mechanism.	GNA11 GNAQ	4.71e-06	2	76	2	26368812
Pubmed	Postsynaptic mechanisms underlying responsiveness of amygdaloid neurons to cholecystokinin are mediated by a transient receptor potential-like current.	GNA11 GNAQ	4.71e-06	2	76	2	17482476
Pubmed	Molecular genetic testing of uveal melanoma from routinely processed and stained cytology specimens.	GNA11 GNAQ	4.71e-06	2	76	2	21945171
Pubmed	Combined PKC and MEK inhibition in uveal melanoma with GNAQ and GNA11 mutations.	GNA11 GNAQ	4.71e-06	2	76	2	24141786
Pubmed	Interaction of the G-protein G11alpha with receptors and phosphoinositidase C: the contribution of G-protein palmitoylation and membrane association.	GNA11 GNAQ	4.71e-06	2	76	2	9175863
Pubmed	The ethnic profile of patients with birthmarks reveals interaction of germline and postzygotic genetics.	GNA11 GNAQ	4.71e-06	2	76	2	28083870
Pubmed	Prostanoid-dependent bladder pain caused by proteinase-activated receptor-2 activation in mice: Involvement of TRPV1 and T-type Ca2+ channels.	TRPV1 CACNA1H	4.71e-06	2	76	2	29289470
Pubmed	Stretch regulates alveologenesis and homeostasis via mesenchymal Gαq/11-mediated TGFβ2 activation.	GNA11 GNAQ	4.71e-06	2	76	2	37102682
Pubmed	Gq/11-Dependent Changes in the Murine Ovarian Transcriptome at the End of Gestation.	GNA11 GNAQ	4.71e-06	2	76	2	26843449
Pubmed	Direct targeting of Gαq and Gα11 oncoproteins in cancer cells.	GNA11 GNAQ	4.71e-06	2	76	2	30890659
Pubmed	Ca2+ signalling in K562 human erythroleukaemia cells: effect of dimethyl sulphoxide and role of G-proteins in thrombin- and thromboxane A2-activated pathways.	GNA11 GNAQ	4.71e-06	2	76	2	7492305
Pubmed	Reduced trabecular bone mass and strength in mice overexpressing Gα11 protein in cells of the osteoblast lineage.	GNA11 GNAQ	4.71e-06	2	76	2	24308950
Pubmed	Gαq and Gα11 contribute to the maintenance of cellular electrophysiology and Ca2+ handling in ventricular cardiomyocytes.	GNA11 GNAQ	4.71e-06	2	76	2	22562663
Pubmed	Functional specificity of G alpha q and G alpha 11 in the cholinergic and glutamatergic modulation of potassium currents and excitability in hippocampal neurons.	GNA11 GNAQ	4.71e-06	2	76	2	11826096
Pubmed	Blue nevi and variants: an update.	GNA11 GNAQ	4.71e-06	2	76	2	21366456
Pubmed	In uveal melanoma Gα-protein GNA11 mutations convey a shorter disease-specific survival and are more strongly associated with loss of BAP1 and chromosomal alterations than Gα-protein GNAQ mutations.	GNA11 GNAQ	4.71e-06	2	76	2	35580369
Pubmed	Gonadotropin and gonadal steroid release in response to a gonadotropin-releasing hormone agonist in Gqalpha and G11alpha knockout mice.	GNA11 GNAQ	4.71e-06	2	76	2	9607776
Pubmed	Genetic Variants Associated with Port-Wine Stains.	RASA1 GNAQ	4.71e-06	2	76	2	26192947
Pubmed	Reverse Phenotyping in Patients with Skin Capillary Malformations and Mosaic GNAQ or GNA11 Mutations Defines a Clinical Spectrum with Genotype-Phenotype Correlation.	GNA11 GNAQ	4.71e-06	2	76	2	31726051
Pubmed	Papillary Hemangioma Harbors Somatic GNA11 and GNAQ Mutations.	GNA11 GNAQ	4.71e-06	2	76	2	37750536
Pubmed	G(alpha)q-deficient mice lack metabotropic glutamate receptor-dependent long-term depression but show normal long-term potentiation in the hippocampal CA1 region.	GNA11 GNAQ	4.71e-06	2	76	2	11438569
Pubmed	GNAQ/GNA11 Mosaicism Is Associated with Abnormal Serum Calcium Indices and Microvascular Neurocalcification.	GNA11 GNAQ	4.71e-06	2	76	2	37802294
Pubmed	Mosaic Activating Mutations in GNA11 and GNAQ Are Associated with Phakomatosis Pigmentovascularis and Extensive Dermal Melanocytosis.	GNA11 GNAQ	4.71e-06	2	76	2	26778290
Pubmed	Distinct profiles of functional discrimination among G proteins determine the actions of G protein-coupled receptors.	GNA11 GNAQ	4.71e-06	2	76	2	26628681
Pubmed	Skeletal Muscle-Specific Activation of Gq Signaling Maintains Glucose Homeostasis.	GNA11 GNAQ	4.71e-06	2	76	2	30936140
Pubmed	TRPM5-dependent amiloride- and benzamil-insensitive NaCl chorda tympani taste nerve response.	TRPV1 TRPM5	4.71e-06	2	76	2	23639808
Pubmed	The time-course of agonist-induced solubilization of trimeric G(q)alpha/G(11)alpha proteins resolved by two-dimensional electrophoresis.	GNA11 GNAQ	4.71e-06	2	76	2	17552882
Pubmed	Patient survival in uveal melanoma is not affected by oncogenic mutations in GNAQ and GNA11.	GNA11 GNAQ	4.71e-06	2	76	2	23778528
Pubmed	High throughput mass spectrometry-based mutation profiling of primary uveal melanoma.	GNA11 GNAQ	4.71e-06	2	76	2	22977135
Pubmed	An experimental strategy to probe Gq contribution to signal transduction in living cells.	GNA11 GNAQ	4.71e-06	2	76	2	33639168
Pubmed	GNAQ and GNA11 mutant nonuveal melanoma: a subtype distinct from both cutaneous and uveal melanoma.	GNA11 GNAQ	4.71e-06	2	76	2	32064597
Pubmed	Mutational analysis of GNAQ and GNA11 to aid therapy management of a choroidal melanoma metastatic to the contralateral orbit.	GNA11 GNAQ	4.71e-06	2	76	2	23572068
Pubmed	Heterogeneity in Mitogen-Activated Protein Kinase (MAPK) Pathway Activation in Uveal Melanoma With Somatic GNAQ and GNA11 Mutations.	GNA11 GNAQ	4.71e-06	2	76	2	31173078
Pubmed	Low mutational burden of eight genes involved in the MAPK/ERK, PI3K/AKT, and GNAQ/11 pathways in female genital tract primary melanomas.	GNA11 GNAQ	4.71e-06	2	76	2	25695059
Pubmed	Frequent and Yet Unreported GNAQ and GNA11 Mutations are Found in Uveal Melanomas.	GNA11 GNAQ	4.71e-06	2	76	2	29209985
Pubmed	Group I metabotropic glutamate receptor signaling via Galpha q/Galpha 11 secures the induction of long-term potentiation in the hippocampal area CA1.	GNA11 GNAQ	4.71e-06	2	76	2	12351712
Pubmed	Cardiac remodeling in Gαq and Gα11 knockout mice.	GNA11 GNAQ	4.71e-06	2	76	2	26476043
Pubmed	Early-onset hypertension associated with extensive cutaneous capillary malformations harboring postzygotic variants in GNAQ and GNA11.	GNA11 GNAQ	4.71e-06	2	76	2	36440997
Pubmed	Loss of Gq/11 family G proteins in the nervous system causes pituitary somatotroph hypoplasia and dwarfism in mice.	GNA11 GNAQ	4.71e-06	2	76	2	15713647
Pubmed	Distinct roles of Galpha(q) and Galpha11 for Purkinje cell signaling and motor behavior.	GNA11 GNAQ	4.71e-06	2	76	2	15175381
Pubmed	GNAQ and GNA11 mutations in melanocytomas of the central nervous system.	GNA11 GNAQ	4.71e-06	2	76	2	22307269
Pubmed	Oncogenic GNAQ and GNA11 mutations in uveal melanoma in Chinese.	GNA11 GNAQ	4.71e-06	2	76	2	25280020
Pubmed	Frequent GNAQ, GNA11, and EIF1AX Mutations in Iris Melanoma.	GNA11 GNAQ	1.41e-05	3	76	2	28700778
Pubmed	Dissecting Gq/11-Mediated Plasma Membrane Translocation of Sphingosine Kinase-1.	GNA11 GNAQ	1.41e-05	3	76	2	33003441
Pubmed	P2Y₂ and Gq/G₁₁ control blood pressure by mediating endothelial mechanotransduction.	GNA11 GNAQ	1.41e-05	3	76	2	26168216
Pubmed	The prostacyclin receptor is isoprenylated. Isoprenylation is required for efficient receptor-effector coupling.	GNA11 GNAQ	1.41e-05	3	76	2	10446129
Pubmed	Specificity of G alpha q and G alpha 11 gene expression in platelets and erythrocytes. Expressions of cellular differentiation and species differences.	GNA11 GNAQ	1.41e-05	3	76	2	8836152
Pubmed	Gqα/G11α deficiency in dorsomedial hypothalamus leads to obesity resulting from decreased energy expenditure and impaired sympathetic nerve activity.	GNA11 GNAQ	1.41e-05	3	76	2	33166186
Pubmed	Absence of pressure overload induced myocardial hypertrophy after conditional inactivation of Galphaq/Galpha11 in cardiomyocytes.	GNA11 GNAQ	1.41e-05	3	76	2	11689889
Pubmed	Diabetes-related defects in sarcoplasmic Ca2+ release are prevented by inactivation of G(alpha)11 and G(alpha)q in murine cardiomyocytes.	GNA11 GNAQ	1.41e-05	3	76	2	20372981
Pubmed	Endocannabinoid-mediated modulation of Gq/11 protein-coupled receptor signaling-induced vasoconstriction and hypertension.	GNA11 GNAQ	1.41e-05	3	76	2	25595485
Pubmed	The orphan receptor GPR139 signals via Gq/11 to oppose opioid effects.	GNA11 GNAQ	1.41e-05	3	76	2	32576659
Pubmed	Thyrocyte-specific Gq/G11 deficiency impairs thyroid function and prevents goiter development.	GNA11 GNAQ	1.41e-05	3	76	2	17694176
Pubmed	Identification of HRAS mutations and absence of GNAQ or GNA11 mutations in deep penetrating nevi.	GNA11 GNAQ	1.41e-05	3	76	2	23599145
Pubmed	Heterotrimeric G proteins of the Gq/11 family are crucial for the induction of maternal behavior in mice.	GNA11 GNAQ	1.41e-05	3	76	2	15340067
Pubmed	Galphao2 regulates vesicular glutamate transporter activity by changing its chloride dependence.	GNA11 GNAQ	1.41e-05	3	76	2	15872115
Pubmed	GNA11 and N-RAS mutations: alternatives for MAPK pathway activating GNAQ mutations in primary melanocytic tumours of the central nervous system.	GNA11 GNAQ	1.41e-05	3	76	2	22758774
Pubmed	Regulation of the epithelial Na+ channel by the RH domain of G protein-coupled receptor kinase, GRK2, and Galphaq/11.	GNA11 GNAQ	1.41e-05	3	76	2	21464134
Pubmed	G protein diversity: a distinct class of alpha subunits is present in vertebrates and invertebrates.	GNA11 GNAQ	1.41e-05	3	76	2	2123549
Pubmed	CXCL2/CXCR2 axis induces cancer stem cell characteristics in CPT-11-resistant LoVo colon cancer cells via Gαi-2 and Gαq/11.	GNA11 GNAQ	1.41e-05	3	76	2	30552676
Pubmed	Intraocular Metastasis in Unilateral Multifocal Uveal Melanoma Without Melanocytosis or Germline BAP1 Mutations.	GNA11 GNAQ	1.41e-05	3	76	2	31580399
Pubmed	G alpha(q) signal in osteoblasts is inhibitory to the osteoanabolic action of parathyroid hormone.	GNA11 GNAQ	1.41e-05	3	76	2	21345793
Pubmed	Normal hematopoiesis and inflammatory responses despite discrete signaling defects in Galpha15 knockout mice.	GNA11 GNAQ	1.41e-05	3	76	2	10629036
Pubmed	Sensory attributes of complex tasting divalent salts are mediated by TRPM5 and TRPV1 channels.	TRPV1 TRPM5	1.41e-05	3	76	2	19244541
Pubmed	Heat But Not Mechanical Hypersensitivity Depends on Voltage-Gated CaV2.2 Calcium Channel Activity in Peripheral Axon Terminals Innervating Skin.	CACNA1B TRPV1	1.41e-05	3	76	2	34353899
Pubmed	Parathyroid-specific double knockout of Gq and G11 alpha-subunits leads to a phenotype resembling germline knockout of the extracellular Ca2+ -sensing receptor.	GNA11 GNAQ	1.41e-05	3	76	2	16988000
Pubmed	Prognostic impact of chromosomal aberrations and GNAQ, GNA11 and BAP1 mutations in uveal melanoma.	GNA11 GNAQ	1.41e-05	3	76	2	28444874
Pubmed	Evidence for the involvement of several intracellular domains in the coupling of oxytocin receptor to G alpha(q/11).	GNA11 GNAQ	1.41e-05	3	76	2	9481484
Pubmed	High frequency of GNA14, GNAQ, and GNA11 mutations in cherry hemangioma: a histopathological and molecular study of 85 cases indicating GNA14 as the most commonly mutated gene in vascular neoplasms.	GNA11 GNAQ	1.41e-05	3	76	2	31189994
Pubmed	Heterotrimeric G alpha q/G alpha 11 proteins function upstream of vascular endothelial growth factor (VEGF) receptor-2 (KDR) phosphorylation in vascular permeability factor/VEGF signaling.	GNA11 GNAQ	1.41e-05	3	76	2	12670961
Pubmed	GNAS, GNAQ, and GNA11 alterations in patients with diverse cancers.	GNA11 GNAQ	1.41e-05	3	76	2	30204251
Pubmed	Structure of the C-terminal guanine nucleotide exchange factor module of Trio in an autoinhibited conformation reveals its oncogenic potential.	GNA11 GNAQ	1.41e-05	3	76	2	30783010
Pubmed	Uterine Gαq/11 signaling, in a progesterone-dependent manner, critically regulates the acquisition of uterine receptivity in the female mouse.	GNA11 GNAQ	1.41e-05	3	76	2	31091422
Pubmed	G(q/11)α and G(s)α mediate distinct physiological responses to central melanocortins.	GNA11 GNAQ	1.41e-05	3	76	2	26595811
Pubmed	The heterotrimeric G-protein alpha-subunit Galphaq regulates TCR-mediated immune responses through an Lck-dependent pathway.	GNA11 GNAQ	1.41e-05	3	76	2	18991294
Pubmed	Tamoxifen-inducible Cre-mediated recombination in adipocytes.	GNA11 GNAQ	1.41e-05	3	76	2	20715175
Pubmed	Selective inhibition of Cav3.3 T-type calcium channels by Galphaq/11-coupled muscarinic acetylcholine receptors.	GNA11 GNAQ	1.41e-05	3	76	2	17535809
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	VANGL2 SLC38A2 GAPVD1 TEX2 VPS13C NUP58 LCOR KCNT1	2.07e-05	529	76	8	14621295
Pubmed	Pasteurella multocida toxin prevents osteoblast differentiation by transactivation of the MAP-kinase cascade via the Gα(q/11)--p63RhoGEF--RhoA axis.	GNA11 GNAQ	2.82e-05	4	76	2	23696743
Pubmed	Interleukin-1α links peripheral CaV2.2 channel activation to rapid adaptive increases in heat sensitivity in skin.	CACNA1B TRPV1	2.82e-05	4	76	2	38643253
Pubmed	Galpha12/13 is essential for directed cell migration and localized Rho-Dia1 function.	GNA11 GNAQ	2.82e-05	4	76	2	16251183
Pubmed	Stabilization of KPNB1 by deubiquitinase USP7 promotes glioblastoma progression through the YBX1-NLGN3 axis.	NLGN3 USP7	2.82e-05	4	76	2	38254206
Pubmed	Promiscuous coupling of receptors to Gq class alpha subunits and effector proteins in pancreatic and submandibular gland cells.	GNA11 GNAQ	2.82e-05	4	76	2	9765251
Pubmed	Ric-8A gene deletion or phorbol ester suppresses tumorigenesis in a mouse model of GNAQ(Q209L)-driven melanoma.	GNA11 GNAQ	2.82e-05	4	76	2	27348266
Pubmed	The Gq/G11-mediated signaling pathway is critical for autocrine potentiation of insulin secretion in mice.	GNA11 GNAQ	2.82e-05	4	76	2	20440069
Pubmed	TRPV1 Nociceptor Activity Initiates USP5/T-type Channel-Mediated Plasticity.	TRPV1 CACNA1H	2.82e-05	4	76	2	27974205
Interaction	GRM4 interactions	USP7 GNAQ GRM3	7.37e-06	11	73	3	int:GRM4
Interaction	ADRA1B interactions	AP2M1 GNA11 GNAQ	2.01e-05	15	73	3	int:ADRA1B
Interaction	TNFRSF10C interactions	SLC38A2 ERGIC3 ANO6 TMEM184C ATP11C	3.61e-05	103	73	5	int:TNFRSF10C
Interaction	RHOC interactions	VANGL2 SLC38A2 AP2M1 RASA1 ANO6 VPS45 MFSD6 UTP20 GNA11 MPP7	4.65e-05	584	73	10	int:RHOC
Interaction	LRRC4 interactions	POMT2 TNPO2 LCOR	4.97e-05	20	73	3	int:LRRC4
Interaction	S1PR1 interactions	TNPO2 USP7 GNAQ ATP2B3 TNPO3	5.39e-05	112	73	5	int:S1PR1
Interaction	C3orf18 interactions	PPP2R5E TNPO2 UTP20 ATP2B3 TNPO3	6.11e-05	115	73	5	int:C3orf18
Interaction	LAMP2 interactions	VANGL2 PIKFYVE SLC38A2 AP2M1 TEX2 ANO6 VPS45 VPS13C TMEM184C ATP11C	6.60e-05	609	73	10	int:LAMP2
Interaction	DOCK9 interactions	TRPV1 PPP2R5E DOCK10 NEB	7.07e-05	61	73	4	int:DOCK9
Interaction	POPDC2 interactions	VANGL2 ANO6 ATP11C	7.67e-05	23	73	3	int:POPDC2
Interaction	RHOJ interactions	VANGL2 SLC38A2 AP2M1 VPS45 VPS13C MFSD6 DOCK10 UTP20 GNA11 MPP7	9.10e-05	633	73	10	int:RHOJ
Cytoband	10q21.2	TMEM26 CABCOCO1	9.66e-05	9	76	2	10q21.2
GeneFamily	Armadillo repeat containing\|Importins	TNPO2 TNPO3	1.16e-03	18	51	2	596
GeneFamily	Calcium voltage-gated channel subunits	CACNA1B CACNA1H	2.43e-03	26	51	2	253
GeneFamily	Transient receptor potential cation channels	TRPV1 TRPM5	2.81e-03	28	51	2	249
GeneFamily	Serpin peptidase inhibitors	SERPINA3 SERPINB11	4.88e-03	37	51	2	739
Coexpression	MIKKELSEN_MEF_ICP_WITH_H3K27ME3	KCNMB2 BRINP3 SULT2B1 CIITA GRM3 PKHD1L1 KLB	2.39e-06	207	76	7	M1963
Coexpression	MIKKELSEN_MEF_ICP_WITH_H3K27ME3	KCNMB2 BRINP3 SULT2B1 CIITA GRM3 PKHD1L1 KLB	3.90e-06	223	76	7	MM838
Coexpression	GSE7218_UNSTIM_VS_ANTIGEN_STIM_THROUGH_IGG_BCELL_UP	UBR1 AGO1 ANO6 TMEM184C UTP20 TNPO3	1.76e-05	187	76	6	M6809
Coexpression	SHEN_SMARCA2_TARGETS_UP	CUL2 RASA1 ZDHHC6 VPS45 VPS13C TMEM126B MFSD6 GNAQ	3.44e-05	429	76	8	M29
Coexpression	MIKKELSEN_ES_ICP_WITH_H3K4ME3_AND_H3K27ME3	BRINP3 SULT2B1 CIITA GRM3 TMEM26	4.80e-05	136	76	5	M2005
Coexpression	MIKKELSEN_ES_ICP_WITH_H3K4ME3_AND_H3K27ME3	BRINP3 SULT2B1 CIITA GRM3 TMEM26	6.73e-05	146	76	5	MM856
ToppCell	LPS_only-Epithelial_airway-airway_epithelial\|LPS_only / Treatment groups by lineage, cell group, cell type	SERPINA3 TRPV1 SERPINB11 TMC5 ANKFN1 DNAH7	1.14e-06	198	76	6	e035380578c01b0243bfef29ca9b50cc17cce771
ToppCell	LPS_only-Epithelial_airway\|LPS_only / Treatment groups by lineage, cell group, cell type	SERPINA3 TRPV1 SERPINB11 TMC5 ANKFN1 DNAH7	1.14e-06	198	76	6	ba090210392e001a3f7bdf09371b3f0e0c8c7ef3
ToppCell	droplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN GPER1 CIITA LCOR MPP7	7.34e-06	157	76	5	a426c54fd1545093d41426e9620862f71bd06f6b
ToppCell	facs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ADCY10 CACNA1B NEB PKHD1L1 ATP2B3	8.55e-06	162	76	5	bf886e22ff2a20353499004b53f25fb9e6574896
ToppCell	5'-GW_trimst-2-LargeIntestine-Epithelial-neuro-epithelial-L_cells_(PYY+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	KCNMB2 CACNA1B BRINP3 KCNH7 KLB	1.08e-05	170	76	5	6a98f47f8c2b5b15e09169bd82eff1e6bf76e5a6
ToppCell	Pericytes-IPF_01\|World / lung cells shred on cell class, cell subclass, sample id	FOXM1 NLGN3 BRINP3 ACTG2 CACNA1H	1.24e-05	175	76	5	ddf721023a7afc8085c5de17aa254a6575444c0f
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TRPM5 CACNA1H TMC5 CCDC171 PKHD1L1	1.35e-05	178	76	5	a107dd98a07086ed0429116095ecda60c9dbef1e
ToppCell	tumor_Lymph_Node_/_Brain-Fibroblasts-Smooth_muscle_cells\|Fibroblasts / Location, Cell class and cell subclass	BRINP3 GPER1 B3GNT2 ACTG2 MPP7	1.39e-05	179	76	5	83506e00fe99b6450efd2f13f716926a0a4b03cd
ToppCell	CV-Moderate-7\|Moderate / Virus stimulation, Condition and Cluster	SLC38A2 GAPVD1 CIITA VPS13C DOCK10	1.62e-05	185	76	5	a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCell	CV-Moderate-7\|CV / Virus stimulation, Condition and Cluster	SLC38A2 GAPVD1 CIITA VPS13C DOCK10	1.67e-05	186	76	5	8571956890fc9894d766ba294a28e376b4aba428
ToppCell	CD8+_Memory_T_cell-CV-7\|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster	UBR1 GAPVD1 CIITA VPS13C DOCK10	1.89e-05	191	76	5	9454f642c3621370fa23640b631301346b300950
ToppCell	COPD-Epithelial-Ciliated\|World / Disease state, Lineage and Cell class	KCNMB2 TMC5 CABCOCO1 ANKFN1 DNAH7	1.94e-05	192	76	5	eab1105cd1a98cfcd3d74dc5c9b89e1799bba59e
ToppCell	IPF-Epithelial-Ciliated\|IPF / Disease state, Lineage and Cell class	KCNMB2 TMC5 CABCOCO1 ANKFN1 DNAH7	1.94e-05	192	76	5	354adc1354bf596fbc60dd45c0169688e6f45165
ToppCell	3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	POMT2 TMC5 CABCOCO1 ANKFN1 DNAH7	2.04e-05	194	76	5	3cd90d01ed5a5ce65aad8284dab2537ec16e3d7c
ToppCell	Control-Epithelial-Ciliated\|World / Disease state, Lineage and Cell class	KCNMB2 TMC5 CABCOCO1 ANKFN1 DNAH7	2.04e-05	194	76	5	958e648138676d46698090b4046cb484083ae449
ToppCell	IPF-Multiplet-Multiplet\|World / Disease state, Lineage and Cell class	KCNMB2 TMC5 CABCOCO1 ANKFN1 DNAH7	2.09e-05	195	76	5	21dbdc803c6947024dc2416e9e21c2ef0af9bc31
ToppCell	IPF-Epithelial\|IPF / Disease state, Lineage and Cell class	KCNMB2 TMC5 CABCOCO1 ANKFN1 DNAH7	2.14e-05	196	76	5	87d9881cfec461a5d89b688a83749b618c519485
ToppCell	LPS_IL1RA_TNF-Epithelial_airway-airway_epithelial\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	SERPINA3 SERPINB11 TMC5 ANKFN1 DNAH7	2.36e-05	200	76	5	da12821e8a0657869ca0f75d351cce2d7605a505
ToppCell	Neuronal-Inhibitory-iA-iA_1(SST_PAX6)-SST-CHRNA4-L1\|Neuronal / cells hierarchy compared to all cells using T-Statistic	RELN RASA1 DOCK10 ATP11C ANKFN1	2.36e-05	200	76	5	e2ced6eb1de9a526c34c7558b9c637854916e624
ToppCell	Neuronal-Inhibitory-iA-iA_1(SST_PAX6)-SST\|Neuronal / cells hierarchy compared to all cells using T-Statistic	RELN RASA1 DOCK10 ATP11C ANKFN1	2.36e-05	200	76	5	53d5e427f0cbf5cf0b63efe4ec01da302f555704
ToppCell	Neuronal-Inhibitory-iA-iA_1(SST_PAX6)-SST-CHRNA4\|Neuronal / cells hierarchy compared to all cells using T-Statistic	RELN RASA1 DOCK10 ATP11C ANKFN1	2.36e-05	200	76	5	9bc924755e5a4c464408e6103b86bf1b4e8c58b5
ToppCell	LPS_IL1RA_TNF-Epithelial_airway\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	SERPINA3 SERPINB11 TMC5 ANKFN1 DNAH7	2.36e-05	200	76	5	72c1d9eeaed4b3ee6b6c602e8aa29efc2e8744eb
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Inner_Medullary_Collecting_Duct_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TRPM5 SULT2B1 TMC5 ANKFN1	9.95e-05	141	76	4	091b5b72811db5fca2314f4a79d467566920e257
ToppCell	COVID-19-kidney-Technical/muscle_(Mes)\|kidney / Disease (COVID-19 only), tissue and cell type	CACNA1B RELN KCNH7 ANKFN1	1.58e-04	159	76	4	5335cbcdeaf2bbd0268bbfe0e45c8c0d288e640d
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L1-3_PVALB_WFDC2\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	VANGL2 KCNMB2 TMEM26 KLB	1.70e-04	162	76	4	164ee1d0543c202831bd349c19e1b36c12f54923
ToppCell	10x5'-blood-Lymphocytic_T_CD4-T_CD4/CD8\|blood / Manually curated celltypes from each tissue	SLC38A2 RASA1 DOCK10 SERINC5	1.70e-04	162	76	4	b4535bcb3f469bc139e73f1122f4070013e5a1de
ToppCell	droplet-Lung-nan-18m-Lymphocytic-plasma_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN CACNA1H SERINC5 CABCOCO1	1.74e-04	163	76	4	5efecdd8a069a822bc9d35b407092925a865e629
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	RELN SNX7 DOCK10 ATP11C	1.74e-04	163	76	4	8d17f44faf0549fe71a9a45f811f50d767275414
ToppCell	droplet-Lung-nan-18m-Lymphocytic-Plasma_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN CACNA1H SERINC5 CABCOCO1	1.74e-04	163	76	4	0d94a427f86e62aba12c397c6d7b8cd297f3a0e5
ToppCell	LPS-IL1RA+antiTNF-Epithelial_airway\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SERPINA3 SERPINB11 TMC5 ANKFN1	1.78e-04	164	76	4	e4d4c59aebe5cacd4ecdb907facd044dc82a831d
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK10 ATP11C ABCC12 GRM3	1.78e-04	164	76	4	f6a961fa2002da7d9679f32af99e1314c0593ef9
ToppCell	droplet-Lung-18m-Hematologic-lymphocytic-plasma_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RELN CACNA1H SERINC5 CABCOCO1	1.78e-04	164	76	4	b92e7c91910d518627376166c6ea9ed333b3d07e
ToppCell	droplet-Lung-18m-Hematologic-lymphocytic-plasma_cell-plasma_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RELN CACNA1H SERINC5 CABCOCO1	1.78e-04	164	76	4	a1e43c6b3e2553f5604100db6e92bf244b70c36d
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CACNA1B SULT2B1 TMC5 ANKFN1	1.91e-04	167	76	4	3edb0570e583bb527165bcd8a4c25a042054043b
ToppCell	Children_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	VANGL2 CACNA1B KCNH7 CACNA1H	1.91e-04	167	76	4	c87ebfa8c3284ad33579190e148c95bcaf670d17
ToppCell	3'-GW_trimst-2-LargeIntestine-Epithelial-neuro-epithelial-EC_cells_(NPW+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	KCNMB2 CACNA1B TRPM5 CACNA1H	1.95e-04	168	76	4	4e1b522c7400c9d87f63c00e4e1dd07136095cd6
ToppCell	3'-Pediatric_IBD-SmallIntestine-Epithelial-Tuft-related-Microfold_cell\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	VANGL2 SERPINA3 BRINP3 TMC5	2.00e-04	169	76	4	a54a8494c1feff29d77ab4737fcfabc84ace5c94
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-5_RORB_HSPB3\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	BRINP3 TMEM26 DNAH7 MPP7	2.04e-04	170	76	4	985c6c9e3c593ed0628a481f06c2c91b2ab5d746
ToppCell	Globus_pallidus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Neurod2-Excitatory_Neuron.Slc17a7.Neurod2-Rorb_(Nucleus_of_the_lateral_olfactory_tract_(LOT))-\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	CIITA ANKFN1 KLB	2.15e-04	68	76	3	6945089858778301a05ecc5895310d768768758c
ToppCell	Globus_pallidus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Neurod2-Excitatory_Neuron.Slc17a7.Neurod2-Rorb_(Nucleus_of_the_lateral_olfactory_tract_(LOT))\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	CIITA ANKFN1 KLB	2.15e-04	68	76	3	ac9d0f473c878b96a422bbdd7088eb8125574dde
ToppCell	390C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-2\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	POMT2 CUL2 SLC35G1 DSE	2.18e-04	173	76	4	b9dee61973559e8c2fef3f2dafd43475b386befb
ToppCell	droplet-Lung-immune-endo-depleted-3m-Myeloid-Myeloid_Dendritic_Type_2\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNMB2 NLGN3 DOCK10 NUP58	2.28e-04	175	76	4	bb058e714d21a0ec8532eaf3c7dd2faf78016bc0
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	BRINP3 SLC22A25 KCNH7 ABCC12	2.43e-04	178	76	4	a48739a588f361b4bc69405d7e256c11f61cf43c
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	BRINP3 TMEM26 DNAH7 MPP7	2.43e-04	178	76	4	0e1bedf991189d0ef9b40dac9281bdf4739333a1
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Endothelial-lymphatic_endothelial-LEC2_(MADCAM1+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RELN B3GNT2 PKHD1L1 MPP7	2.49e-04	179	76	4	dfd5b25f2a6a5a8bf4714f1516cb0997de72b06f
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5-Exc_L4-5_RORB_HNRNPA1P46\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	BRINP3 SLC22A25 KCNH7 GRM3	2.54e-04	180	76	4	8923a42a6db9c6e9f3ce2ca9530e620dfea700ba
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	POMT2 TMC5 CABCOCO1 DNAH7	2.54e-04	180	76	4	1f1af4474f3f0ac3c0d6b1a6c875c354d36d8eec
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6-Inh_L1_PAX6_CA4\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RELN DOCK10 ATP11C TMC5	2.54e-04	180	76	4	392bc71a69653ba12de31bed4e9357f181094641
ToppCell	COVID-19-Epithelial-Ionocytes\|Epithelial / Condition, Lineage and Cell class	GPER1 SLC35B4 DOCK10 CACNA1H	2.59e-04	181	76	4	4a8d4f2709c1b25f908867f1b2fae1d2d0abf1d4
ToppCell	facs-Marrow-T-cells-3m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TEX2 VPS13C DOCK10 DSE	2.59e-04	181	76	4	7286700396676fdc41d9723979b8b408177aceb9
ToppCell	Control-Epithelial_cells-Airway_ciliated\|Control / group, cell type (main and fine annotations)	KCNMB2 CABCOCO1 ANKFN1 DNAH7	2.65e-04	182	76	4	fb725d10d9ed25dfc6d5bb69cfef78513f7d3e8f
ToppCell	Hippocampus-Neuronal-Inhibitory\|Hippocampus / BrainAtlas - Mouse McCarroll V32	KCNMB2 RELN NEB GFPT1	2.65e-04	182	76	4	b54ae650c04dfd0759c5f5e752b9bf684dd36516
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TRPM5 TMC5 CCDC171 PKHD1L1	2.65e-04	182	76	4	9966f42c338cbd471efa8ffc765a6ce93693aa75
ToppCell	TCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Squamous_Cell_Carcinoma-3\|TCGA-Lung / Sample_Type by Project: Shred V9	VANGL2 ADCY10 CACNA1B SLC35G1	2.76e-04	184	76	4	ea4ccebe2d54279fcc517e4f0bfa652b91a808bb
ToppCell	PBMC-Mild-cDC_9\|Mild / Compartment, Disease Groups and Clusters	CACNA1B GPER1 UTP20 DTX3L	2.76e-04	184	76	4	2e0c9a2c40c892a2d435eafb31f1f838de9baf15
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_ADARB2_ADAM33\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RELN RASA1 DOCK10 ANKFN1	2.82e-04	185	76	4	487fa382232564f075960899d50afa0edae5d258
ToppCell	COVID-19-Epithelial_cells-Airway_ciliated\|COVID-19 / group, cell type (main and fine annotations)	KCNMB2 CABCOCO1 ANKFN1 DNAH7	2.82e-04	185	76	4	18a40f0a338aa398d81384b5159fb80ce8a2020c
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RELN RASA1 DOCK10 ATP11C	2.88e-04	186	76	4	310d16f4e5cffee3ea6d7635508c513a3b92131e
ToppCell	facs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CACNA1B NLGN3 BRINP3 ANKFN1	2.88e-04	186	76	4	bdc87e4631a8ea73e262e541aa84a28f24c94b00
ToppCell	COPD-Epithelial-Ciliated\|COPD / Disease state, Lineage and Cell class	KCNMB2 CABCOCO1 ANKFN1 DNAH7	2.94e-04	187	76	4	f0fd0792f6926f705d175f6e6fd480f12c7a3bd4
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_ADARB2_ADAM33\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RASA1 DOCK10 ATP11C ANKFN1	2.94e-04	187	76	4	02105c82a9ba79d2f19e002188377fc3440770c2
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM2_(12)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	BRINP3 ACTG2 TMEM26 ANKFN1	3.00e-04	188	76	4	3004e961d214919e08c7cd5f10c3de5cf85b35a3
ToppCell	Control-Epithelial-Ciliated\|Control / Disease state, Lineage and Cell class	KCNMB2 CABCOCO1 ANKFN1 DNAH7	3.06e-04	189	76	4	c007fccd08728db3ea99af9da91d67b9b16dabb3
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	POMT2 TMC5 CABCOCO1 DNAH7	3.06e-04	189	76	4	b4b93bd10b7e3cc16e54ff73beac230f519c010a
ToppCell	COPD-Epithelial-Ciliated\|Epithelial / Disease state, Lineage and Cell class	KCNMB2 CABCOCO1 ANKFN1 DNAH7	3.06e-04	189	76	4	3e77883db34722b9ce0a03ea74caefc92dc7feff
ToppCell	Hippocampus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	ADCY10 TRPV1 PKHD1L1	3.10e-04	77	76	3	a799ccdb84014e978d9fbccf3d2fee8fbeac7b0c
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial-Lgr5-_amplifying_undifferentiated_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SNX7 VPS13C USP7 UTP20	3.12e-04	190	76	4	36e83995021ba16690f84e2077a9e8baec547d05
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial-epithelial_cell_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SNX7 VPS13C USP7 UTP20	3.12e-04	190	76	4	d26be9e1b676f750e716b91ebc3598fac3735612
ToppCell	368C-Lymphocytic-NK_cells-NK_cell_D3\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	CUL2 USP7 LCOR TNPO3	3.18e-04	191	76	4	d7920f4a602b50d0ef064eb47001e71939695ed2
ToppCell	nucseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	KCNMB2 CABCOCO1 ANKFN1 DNAH7	3.18e-04	191	76	4	e417bf491f8b8d7838a61f7f4f6b1740ba97aa3f
ToppCell	nucseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	KCNMB2 CABCOCO1 ANKFN1 DNAH7	3.18e-04	191	76	4	9d31c8424d35bdc0c27188b68bfd0f731af3600b
ToppCell	nucseq-Epithelial-Epithelial_Airway\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	KCNMB2 CABCOCO1 ANKFN1 DNAH7	3.18e-04	191	76	4	1c528f72c9ef3ef3a850b05e4a9715190832270c
ToppCell	Entopeduncular-Macroglia-POLYDENDROCYTE-P1-P1_1-Tnr\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	TRPM5 TMEM217 NEB	3.22e-04	78	76	3	1ddbb2247450a8b1c159f524dee15bf688748955
ToppCell	Entopeduncular-Macroglia-POLYDENDROCYTE-P1-P1_1-Tnr-Polydendrocyte.Tnr.Ctps_(Ctps)\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	TRPM5 TMEM217 NEB	3.22e-04	78	76	3	2b0973122052bb26153f066e7b87c26f8a319698
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Pericyte\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	GPER1 ACTG2 CACNA1H GRM3	3.24e-04	192	76	4	09cb5b89a164ac7444774ccc8c90323c8ea2026b
ToppCell	IPF-Epithelial-Ciliated\|World / Disease state, Lineage and Cell class	KCNMB2 CABCOCO1 ANKFN1 DNAH7	3.24e-04	192	76	4	d903bbd6c18e29e2c4cdedeb3fea1fd5ad7baa11
ToppCell	Control-Epithelial-Ciliated\|Epithelial / Disease state, Lineage and Cell class	KCNMB2 CABCOCO1 ANKFN1 DNAH7	3.31e-04	193	76	4	0e37d454f3735edd936ee9a5f5f516ac3aad400e
ToppCell	IPF-Epithelial-Ciliated\|Epithelial / Disease state, Lineage and Cell class	KCNMB2 CABCOCO1 ANKFN1 DNAH7	3.31e-04	193	76	4	ad58f5080e0ba65c845056ea6b79037b636e9c64
ToppCell	IPF-Multiplet-Multiplet\|IPF / Disease state, Lineage and Cell class	KCNMB2 TMC5 ANKFN1 DNAH7	3.44e-04	195	76	4	fce0c29574bb7aab181b9c00feb42681e285d1f2
ToppCell	COPD-Endothelial-Lymphatic\|Endothelial / Disease state, Lineage and Cell class	SLC38A2 RELN PKHD1L1 MPP7	3.44e-04	195	76	4	e91ce548ae7224661ee5d2f2639794a5f69798ee
ToppCell	3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	POMT2 TMC5 CABCOCO1 DNAH7	3.44e-04	195	76	4	79dc031258579ea328181dda33710dd897f1064a
ToppCell	3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	POMT2 TMC5 CABCOCO1 DNAH7	3.44e-04	195	76	4	db4270c135c392ed443670981656e3cd5b95939d
ToppCell	IPF-Multiplet\|IPF / Disease state, Lineage and Cell class	KCNMB2 TMC5 ANKFN1 DNAH7	3.44e-04	195	76	4	eacc0449ae6f3ad8002268cd061467684c6fb9a7
ToppCell	3'-Airway_Nasal-Epithelial-Airway_ciliated\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	POMT2 TMC5 CABCOCO1 DNAH7	3.44e-04	195	76	4	6365e3893e38231090ec2dbef010dec71dea3d07
ToppCell	Control_saline-Epithelial_airway\|Control_saline / Treatment groups by lineage, cell group, cell type	SERPINA3 SERPINB11 TMC5 DNAH7	3.64e-04	198	76	4	e6863238e022ecfb6a8e3f4b7661b376e92c5d8f
ToppCell	Control_saline-Epithelial_airway-airway_epithelial\|Control_saline / Treatment groups by lineage, cell group, cell type	SERPINA3 SERPINB11 TMC5 DNAH7	3.64e-04	198	76	4	e7aa42e5fbd42c68f50cda4a8f3aa464c862c007
ToppCell	LPS_only-Epithelial_airway-airway_epithelial-Ciliated\|LPS_only / Treatment groups by lineage, cell group, cell type	TMC5 ANKFN1 DNAH7 KLB	3.64e-04	198	76	4	6d90b541fde357fbb40f8f7d4e8628a48b679718
ToppCell	Parenchyma_COVID-19-Endothelial-TX-Lymphatic\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	SLC38A2 RELN PKHD1L1 MPP7	3.71e-04	199	76	4	88f33b8dcd837abfa1d12c28719e073a7da6e979
ToppCell	LPS_only-Epithelial_airway-airway_epithelial-Airway-Club\|LPS_only / Treatment groups by lineage, cell group, cell type	SERPINA3 TRPV1 SERPINB11 TMC5	3.71e-04	199	76	4	165ac94b2d56072ad43358b5127d77555221e2d8
ToppCell	Lung_Parenchyma-Severe-Endothelial-Endothelial-Lymphatic\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SLC38A2 RELN PKHD1L1 MPP7	3.71e-04	199	76	4	64b19aff72e2a109cb5857cb248bd4712dd49b43
ToppCell	LPS_anti-TNF-Epithelial_airway-airway_epithelial\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	SERPINA3 SERPINB11 TMC5 DNAH7	3.71e-04	199	76	4	60919c2af31d39a2d36d7bc432e43dab2a4e05fb
ToppCell	Biopsy_Control_(H.)-Epithelial-MUC5B+\|Biopsy_Control_(H.) / Sample group, Lineage and Cell type	SERPINA3 SULT2B1 SERPINB11 TMC5	3.71e-04	199	76	4	4ab45996e6bca406c77895a5998982b8ab1cf210
ToppCell	Lung_Parenchyma-Severe-Endothelial-Endothelial-Lymphatic-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SLC38A2 RELN PKHD1L1 MPP7	3.71e-04	199	76	4	2b9e1e069b36b3a61cc3e384f4523687b0e03905
ToppCell	LPS_anti-TNF-Epithelial_airway\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	SERPINA3 SERPINB11 TMC5 DNAH7	3.71e-04	199	76	4	6aca164bbbb961f34b1e6f1857f91ade5c059405
ToppCell	LPS_IL1RA-Epithelial_airway-airway_epithelial\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	SERPINA3 SERPINB11 TMC5 DNAH7	3.79e-04	200	76	4	cf191104484bfb2b9f87de416b9453135f8833c1
ToppCell	Neuronal-Inhibitory-iA-iA_1(SST_PAX6)-SST-BAGE2\|Neuronal / cells hierarchy compared to all cells using T-Statistic	RELN RASA1 DOCK10 ANKFN1	3.79e-04	200	76	4	26f07d271e984f375145e4c10528fba44a5811e1
ToppCell	Neuronal-Inhibitory-iA-iA_1(SST_PAX6)-SST-BAGE2-L1-2\|Neuronal / cells hierarchy compared to all cells using T-Statistic	RELN RASA1 DOCK10 ANKFN1	3.79e-04	200	76	4	c3637827ceba16b0d7956c280dd2ddbc8b1ba55e
ToppCell	Neuronal-Inhibitory-iA-iA_1(SST_PAX6)\|Neuronal / cells hierarchy compared to all cells using T-Statistic	RELN RASA1 DOCK10 ATP11C	3.79e-04	200	76	4	d0167f96314be78b6d867bbcc6e4396071d931b8
ToppCell	LPS_IL1RA-Epithelial_airway\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	SERPINA3 SERPINB11 TMC5 DNAH7	3.79e-04	200	76	4	a5ae33dd4dc1ff6e1a1eec22c4d523d5ab657607
ToppCell	Neuronal-Inhibitory-iA-iA_1(SST_PAX6)-NMBR\|Neuronal / cells hierarchy compared to all cells using T-Statistic	RELN RASA1 DOCK10 ATP11C	3.79e-04	200	76	4	862db57d043bdf3cb059fbfc8b29bc1eafdf64ec
Disease	Sturge-Weber Syndrome	RASA1 GNAQ	6.55e-06	2	76	2	C0038505
Disease	Phakomatosis cesioflammea	GNA11 GNAQ	6.55e-06	2	76	2	C3838883
Disease	Port-Wine Stain	RASA1 GNAQ	6.55e-06	2	76	2	C0235752
Disease	Congenital hemangioma	GNA11 GNAQ	6.55e-06	2	76	2	C0235753
Disease	Port-wine stain with oculocutaneous melanosis	GNA11 GNAQ	6.55e-06	2	76	2	C1274879
Disease	Malignant melanoma of iris	GNA11 GNAQ	6.51e-05	5	76	2	C0346373
Disease	Malignant melanoma of choroid	GNA11 GNAQ	6.51e-05	5	76	2	C0346388
Disease	alpha-1-antichymotrypsin complex measurement	PIKFYVE SERPINA3	1.36e-04	7	76	2	EFO_0008018
Disease	Uveal melanoma	GNA11 GNAQ	1.81e-04	8	76	2	C0220633
Disease	Generalized hypotonia	AP2M1 AGO1	6.73e-04	15	76	2	C1858120
Disease	Epilepsy, Benign Psychomotor, Childhood	TRPV1 GRM3	1.60e-03	23	76	2	C0393672
Disease	Epilepsy, Lateral Temporal	TRPV1 GRM3	1.60e-03	23	76	2	C0393682
Disease	Uncinate Epilepsy	TRPV1 GRM3	1.60e-03	23	76	2	C0014558
Disease	Epilepsy, Temporal Lobe	TRPV1 GRM3	1.60e-03	23	76	2	C0014556
Disease	response to paliperidone, schizophrenia symptom severity measurement	POMT2 CACNA1B BRINP3 VPS45	2.37e-03	216	76	4	EFO_0007925, EFO_0007927

Protein segments in the cluster

Peptide	Gene	Start	Entry
TYLVIINNMSQLFAM	TMEM184C	211	Q9NVA4
AQAIFASMARAMQKY	VANGL2	391	Q9ULK5
LVYNVLKAFMEMNST	PPP2R5E	406	Q16537
MKINNIQVFGYSMHF	BRINP3	661	Q76B58
MDFSIIQYSKFMTLL	CABCOCO1	1	Q8IVU9
IQYSKFMTLLAMSLQ	CABCOCO1	6	Q8IVU9
SQTMMVLVNYIFFKA	SERPINA3	201	P01011
MVSLRVMDVQYNKFT	CIITA	1071	P33076
AMIKSFMDVYQLAST	CCDC171	1201	Q6TFL3
QESKIMFVVNAVYAM	GRM3	386	Q14832
MMLNIDVSATAFYKA	AGO1	211	Q9UL18
TQIMFETFNVPAMYV	ACTG2	121	P63267
FMYTMKKFLISNSSQ	ADCY10	496	Q96PN6
HQTFYTIQMFMANVL	ADCY10	551	Q96PN6
IALNTVVLMMKFYDA	CACNA1B	1481	Q00975
SEHYTIIFNTFVMMQ	ATP2B3	966	Q16720
TLMEQYMKATATQFV	RASA1	796	P20936
TKLVYQNIFTAMQAM	GNAQ	76	P50148
YENSLTMKMFLFQFV	ANO6	546	Q4KMQ2
IDVMNGMFLNYRKIF	PABPC1L2A	146	Q5JQF8
MSLVNVVMENFRKYQ	KCNMB2	156	Q9Y691
QVLEVKMQVEYMSFS	INTS11	376	Q5TA45
VAMMFIINFEYVTDN	KCNH7	121	Q9NS40
YSQLITLVNFMKSVM	GAPVD1	411	Q14C86
YMADAKTIVNVQTMF	KCNT1	876	Q5JUK3
MQRMIQQFAAEYTSK	LCOR	1	Q96JN0
QASMMFQYFVKVVPT	ERGIC3	271	Q9Y282
FQEMIKSAQIMESQY	MPP7	521	Q5T2T1
IFFVMLAMQLTYFQR	DSE	911	Q9UL01
QNVNAAMVFEFLYKM	AP2M1	71	Q96CW1
VTFVYALYQIKEMMQ	MFSD6	696	Q6ZSS7
VLVSTRKQNYMMNFS	RELN	3426	P78509
FSKNDVMLSAVVMTY	NLGN3	546	Q9NZ94
VMENLFYGRKMAQVF	PIKFYVE	1936	Q9Y2I7
YVFKMVNNYISMFSS	DOCK10	1071	Q96BY6
QNSLMKRVFDTYMLF	DOCK10	1511	Q96BY6
VKLFAANYMMNVIEV	DTX3L	366	Q8TDB6
TKLVYQNIFTAMQAM	GNA11	76	P29992
AFFSEKILQVYEMMI	DNAH7	1586	Q8WXX0
MVTTYQMAVLLAFNN	CUL2	576	Q13617
YMAMIQFAINSTERK	FOXM1	241	Q08050
TAIYMMKNFLSQVLQ	KLB	431	Q86Z14
SNYIFTAIFVAEMMV	CACNA1H	1331	O95180
MVFLIMFNVIVYHQT	SLC22A25	21	Q6T423
SMAMQKIYQTFVALA	NUP58	386	Q9BVL2
NMQMISFAKDTVLTY	OR2B2	316	Q9GZK3
NYKDALSVVFEVMMQ	MRPS27	156	Q92552
SEVMFAMKQFEQLFL	UTP20	406	O75691
YAIMVTMFFTVSVVN	SLC35B4	66	Q969S0
MTYFKVINQMLVFFA	TMEM26	276	Q6ZUK4
FSAMKANTMSNYTLL	SULT2B1	246	O00204
FFIMAAMLSMVKYNS	POMT2	201	Q9UKY4
KEMTQNIYQMATFGT	TMEM126B	66	Q8IUX1
YTSQFVSLVMFALMM	GFPT1	496	Q06210
TFMSLFLQVNMYSSV	GPER1	131	Q99527
TVEMMYQIGTFKLAF	SERPINB11	211	Q96P15
VAFSVIAMFNVMKFS	ABCC12	376	Q96J65
FMEMNNFIELFSQKI	SNX7	186	Q9UNH6
MANVFIYFIMEVSKS	B3GNT2	16	Q9NY97
MQLFFYELQMAVKAL	ANKFN1	676	Q8N957
SMYVTVEMQKFLGSF	ATP11C	361	Q8NB49
LKQQRMYFVFAQMLS	ATP11C	1051	Q8NB49
IHAAFIFVMTMYTQL	ZDHHC6	156	Q9H6R6
MNLLIAMFSYTFQVV	TRPM5	971	Q9NZQ8
DNTKFVTSMYNEILM	TRPV1	301	Q8NER1
MQNIGAMSSYLFIVK	SLC38A2	156	Q96QD8
NVSKISFFAMFLMYL	SLC38A2	326	Q96QD8
TLVQKTLAQAMMYTQ	TNPO2	611	O14787
VFFLASLYVMMTVTN	SERINC5	396	Q86VE9
MNKIMSYSSDFRQIF	UBR1	321	Q8IWV7
MNVVFAVKQYISKMI	VPS45	1	Q9NRW7
LQFKYFMVLIQEMAL	VPS13C	3256	Q709C8
NKIAMFQTYAEVTMI	PKHD1L1	261	Q86WI1
YFAAQTMKMKIQTSF	TNPO3	61	Q9Y5L0
IMKTMDVVFAFIFQI	SLC35G1	316	Q2M3R5
QMIMLFIMFYSKNIS	TMC5	801	Q6UXY8
FTIMAVDMYLIFEQK	TMEM217	21	Q8N7C4
FQKVFVMPNMDDVYI	TEX2	1086	Q8IWB9
TLFFTNQLRKAVYMM	USP7	231	Q93009
ALQYMNFMNVIFAAQ	GTF2H3	171	Q13889
FENMKDQIYFMQTET	NEB	316	P20929