Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiondeubiquitinase activity

USP17L7 USP17L4 USP17L2 USP10 COPS5 USP17L8

8.63e-051241166GO:0101005
GeneOntologyMolecularFunctionubiquitin-like protein peptidase activity

USP17L7 USP17L4 USP17L2 USP10 COPS5 USP17L8

1.49e-041371166GO:0019783
DomainCell_morpho_N

FRYL FRY

3.69e-0521142IPR025614
DomainCell_Morphogen_C

FRYL FRY

3.69e-0521142IPR025481
DomainTscrpt_reg_Wos2-domain

MYB MYBL1

3.69e-0521142IPR012642
DomainMOR2-PAG1_mid

FRYL FRY

3.69e-0521142IPR029473
DomainMOR2-PAG1_mid

FRYL FRY

3.69e-0521142PF14228
DomainMOR2-PAG1_C

FRYL FRY

3.69e-0521142PF14225
DomainMOR2-PAG1_N

FRYL FRY

3.69e-0521142PF14222
DomainLMSTEN

MYB MYBL1

3.69e-0521142PF07988
DomainUSP_1

USP17L7 USP17L4 USP17L2 USP10 USP17L8

6.84e-05701145PS00972
DomainUCH

USP17L7 USP17L4 USP17L2 USP10 USP17L8

7.33e-05711145PF00443
DomainUSP_2

USP17L7 USP17L4 USP17L2 USP10 USP17L8

7.33e-05711145PS00973
DomainUSP_3

USP17L7 USP17L4 USP17L2 USP10 USP17L8

7.84e-05721145PS50235
DomainUSP_dom

USP17L7 USP17L4 USP17L2 USP10 USP17L8

7.84e-05721145IPR028889
DomainPeptidase_C19_UCH

USP17L7 USP17L4 USP17L2 USP10 USP17L8

7.84e-05721145IPR001394
DomainCmyb_C

MYB MYBL1

1.10e-0431142PF09316
DomainC-myb_C

MYB MYBL1

1.10e-0431142IPR015395
DomainUSP_CS

USP17L7 USP17L2 USP10 USP17L8

7.09e-04661144IPR018200
DomainHTH_MYB

MYB MYBL1

1.29e-0391142PS51294
DomainMyb_dom

MYB MYBL1

1.29e-0391142IPR017930
DomainPkinase_C

STK38 PRKACA PRKCE

2.14e-03421143PF00433
DomainWW

WWOX SMURF1 SMURF2

2.95e-03471143PF00397
DomainWW

WWOX SMURF1 SMURF2

3.14e-03481143SM00456
DomainWW_DOMAIN_1

WWOX SMURF1 SMURF2

3.73e-03511143PS01159
DomainWW_DOMAIN_2

WWOX SMURF1 SMURF2

3.73e-03511143PS50020
DomainWW_dom

WWOX SMURF1 SMURF2

3.94e-03521143IPR001202
DomainHABP4_PAI-RBP1

USP17L7 USP17L2

4.19e-03161142PF04774
DomainHABP4_PAIRBP1-bd

USP17L7 USP17L2

4.19e-03161142IPR006861
DomainAld_DH_CS_CYS

ALDH1A1 ALDH6A1

4.73e-03171142IPR016160
DomainAGC-kinase_C

STK38 PRKACA PRKCE

4.85e-03561143IPR000961
DomainAGC_KINASE_CTER

STK38 PRKACA PRKCE

4.85e-03561143PS51285
DomainS_TK_X

STK38 PRKACA PRKCE

4.85e-03561143SM00133
DomainALDEHYDE_DEHYDR_CYS

ALDH1A1 ALDH6A1

5.30e-03181142PS00070
DomainALDEHYDE_DEHYDR_GLU

ALDH1A1 ALDH6A1

5.30e-03181142PS00687
Domain-

ALDH1A1 ALDH6A1

5.90e-031911423.40.605.10
DomainAldedh

ALDH1A1 ALDH6A1

5.90e-03191142PF00171
DomainAld_DH_C

ALDH1A1 ALDH6A1

5.90e-03191142IPR016163
DomainAld_DH_N

ALDH1A1 ALDH6A1

5.90e-03191142IPR016162
DomainAld_DH/histidinol_DH

ALDH1A1 ALDH6A1

5.90e-03191142IPR016161
DomainAldehyde_DH_dom

ALDH1A1 ALDH6A1

5.90e-03191142IPR015590
Domain-

ALDH1A1 ALDH6A1

5.90e-031911423.40.309.10
PathwayREACTOME_UB_SPECIFIC_PROCESSING_PROTEASES

USP17L7 USP17L4 USP17L2 USP10 TNKS2 SMURF2 IL33 USP17L8

1.77e-05191848MM15289
PathwayWP_PATHWAYS_AFFECTED_IN_ADENOID_CYSTIC_CARCINOMA

ERBIN JMJD1C MGA MYB MYBL1

4.16e-0565845M39682
PathwayPID_HDAC_CLASSI_PATHWAY

SMURF1 GATAD2B PRKACA HDAC10 TNFRSF1A

4.48e-0566845M101
PathwayREACTOME_RAS_PROCESSING

USP17L7 USP17L4 USP17L2 USP17L8

1.45e-0445844MM15671
PathwayREACTOME_DEUBIQUITINATION

USP17L7 USP17L4 USP17L2 USP10 TNKS2 SMURF2 IL33 USP17L8

1.65e-04262848MM15286
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

PRUNE2 RAD52 MBTPS1 WWOX SLC16A9 UVSSA SMURF1 GRIK1 FRYL SLC30A4 ERBIN JMJD1C DNAH1 USP10 ABLIM1 FAM13A PTPRS PRKCE COPS5 SMURF2 NXPH4 TRAPPC9 TBL1X

1.00e-0914891182328611215
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

CACNA1A MAP2K4 SGIP1 SYNE1 ERBIN PREPL GATAD2B USP10 ABLIM1 FRY DST PTPRD ANAPC1 PTPRS PRKACA PRKCE MGA TBL1X

4.55e-099631181828671696
Pubmed

CDK4/6-dependent activation of DUB3 regulates cancer metastasis through SNAIL1.

USP17L7 USP17L4 USP17L2 USP10 USP17L8

4.62e-0919118528067227
Pubmed

High Dub3 expression in mouse ESCs couples the G1/S checkpoint to pluripotency.

USP17L7 USP17L4 USP17L2 USP17L8

2.60e-0810118424207026
Pubmed

Cell cycle-dependent expression of Dub3, Nanog and the p160 family of nuclear receptor coactivators (NCoAs) in mouse embryonic stem cells.

USP17L7 USP17L4 USP17L2 USP17L8

6.10e-0812118424695638
Pubmed

ES cell neural differentiation reveals a substantial number of novel ESTs.

USP17L7 USP17L4 USP17L2 USP17L8

1.23e-0714118411793228
Pubmed

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.

HIVEP1 SYNE1 PREPL JMJD1C PHGDH IVNS1ABP ABLIM1 DST ALMS1 ANKRD1 TNKS2 MGA

1.38e-074971181223414517
Pubmed

Characterization of the mouse JAB1 cDNA and protein.

DST COPS5 MYBL1

1.52e-074118310721695
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

CASP8AP2 HIVEP1 WWOX TTC28 RFX1 JMJD1C DST ALMS1 ANAPC1 MGA TBL1X

2.01e-074181181134709266
Pubmed

DUB-1, a deubiquitinating enzyme with growth-suppressing activity.

USP17L7 USP17L4 USP17L2 USP17L8

7.21e-072111848622927
Pubmed

DUB-1A, a novel deubiquitinating enzyme subfamily member, is polyubiquitinated and cytokine-inducible in B-lymphocytes.

USP17L7 USP17L4 USP17L2 USP17L8

7.21e-0721118414583620
Pubmed

DUB-2A, a new member of the DUB subfamily of hematopoietic deubiquitinating enzymes.

USP17L7 USP17L4 USP17L2 USP17L8

7.21e-0721118411468161
Pubmed

The murine DUB-1 gene is specifically induced by the betac subunit of interleukin-3 receptor.

USP17L7 USP17L4 USP17L2 USP17L8

7.21e-072111848756639
Pubmed

Lymphocyte-specific murine deubiquitinating enzymes induced by cytokines.

USP17L7 USP17L4 USP17L2 USP17L8

7.21e-0721118412447969
Pubmed

DUB-1, a fate determinant of dynein heavy chain in B-lymphocytes, is regulated by the ubiquitin-proteasome pathway.

USP17L7 USP17L4 USP17L2 USP17L8

7.21e-0721118418980247
Pubmed

JAK2 is required for induction of the murine DUB-1 gene.

USP17L7 USP17L4 USP17L2 USP17L8

8.78e-072211849154835
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

PRUNE2 CASP8AP2 TTC28 SYNE1 ERBIN ABLIM1 DST ALMS1

1.08e-06225118812168954
Pubmed

DUB-2 is a member of a novel family of cytokine-inducible deubiquitinating enzymes.

USP17L7 USP17L4 USP17L2 USP17L8

1.27e-062411848995226
Pubmed

Interleukin 1 receptor signaling regulates DUBA expression and facilitates Toll-like receptor 9-driven antiinflammatory cytokine production.

USP17L7 USP17L4 USP17L2 USP17L8

1.51e-0625118421115691
Pubmed

Decabromodiphenyl ethane affects embryonic development by interfering with nuclear F-actin in zygotes and leads to cognitive and social disorders in offspring mice.

USP17L7 USP17L4 USP17L2 USP17L8

1.78e-0626118435816173
Pubmed

Minor Splicing Factors Zrsr1 and Zrsr2 Are Essential for Early Embryo Development and 2-Cell-Like Conversion.

USP17L7 USP17L4 USP17L2 USP17L8

2.80e-0629118432527007
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

TTC28 NBN RFX1 ERBIN JMJD1C PHGDH USP10 ABLIM1 ALMS1 ANAPC1 MGA

2.87e-065491181138280479
Pubmed

HENA, heterogeneous network-based data set for Alzheimer's disease.

SYNE1 FRYL GATAD2B DST ALMS1 TNKS2

3.58e-06120118631413325
Pubmed

Cdc25A and Dub3 in a high-stakes balancing act.

USP17L7 USP17L4 USP17L2 USP17L8

4.77e-0633118420228807
Pubmed

The DUB/USP17 deubiquitinating enzymes: a gene family within a tandemly repeated sequence, is also embedded within the copy number variable beta-defensin cluster.

USP17L7 USP17L4 USP17L2 USP17L8

5.40e-0634118420403174
Pubmed

DUB-3, a cytokine-inducible deubiquitinating enzyme that blocks proliferation.

USP17L7 USP17L4 USP17L2 USP17L8

5.40e-0634118414699124
Pubmed

The DUB/USP17 deubiquitinating enzymes, a multigene family within a tandemly repeated sequence.

USP17L7 USP17L4 USP17L2 USP17L8

5.40e-0634118415780755
Pubmed

USP17 regulates Ras activation and cell proliferation by blocking RCE1 activity.

USP17L7 USP17L4 USP17L2 USP17L8

5.40e-0634118419188362
Pubmed

Unstable transmission of the RS447 human megasatellite tandem repetitive sequence that contains the USP17 deubiquitinating enzyme gene.

USP17L7 USP17L4 USP17L2 USP17L8

5.40e-0634118411941478
Pubmed

Hyaluronan- and RNA-binding deubiquitinating enzymes of USP17 family members associated with cell viability.

USP17L7 USP17L4 USP17L2 USP17L8

5.40e-0634118417109758
Pubmed

The deubiquitinating enzyme USP17 is highly expressed in tumor biopsies, is cell cycle regulated, and is required for G1-S progression.

USP17L7 USP17L4 USP17L2 USP17L8

5.40e-0634118420388806
Pubmed

Polyclonal and monoclonal antibodies specific for USP17, a proapoptotic deubiquitinating enzyme.

USP17L7 USP17L4 USP17L2 USP17L8

5.40e-0634118420715989
Pubmed

Human megasatellite DNA RS447: copy-number polymorphisms and interspecies conservation.

USP17L7 USP17L4 USP17L2 USP17L8

5.40e-063411849806828
Pubmed

The ubiquitin-specific protease 17 is involved in virus-triggered type I IFN signaling.

USP17L7 USP17L4 USP17L2 USP17L8

5.40e-0634118420368735
Pubmed

The RS447 human megasatellite tandem repetitive sequence encodes a novel deubiquitinating enzyme with a functional promoter.

USP17L7 USP17L4 USP17L2 USP17L8

5.40e-0634118410936051
Pubmed

The deubiquitinating enzyme USP17 is essential for GTPase subcellular localization and cell motility.

USP17L7 USP17L4 USP17L2 USP17L8

5.40e-0634118421448158
Pubmed

NOTCH1 nuclear interactome reveals key regulators of its transcriptional activity and oncogenic function.

STK38 FRYL RFX1 GATAD2B ANAPC1 TRAPPC9

5.43e-06129118623022380
Pubmed

Functional proteomics mapping of a human signaling pathway.

HIVEP1 TPRN SMURF1 RFX1 ERBIN GATAD2B DST TNKS2 MGA COPS5 SMURF2

5.77e-065911181115231748
Pubmed

Cytokine-regulated protein degradation by the ubiquitination system.

USP17L7 USP17L4 USP17L2 USP17L8

6.08e-0635118416611142
Pubmed

Lys-63-specific deubiquitination of SDS3 by USP17 regulates HDAC activity.

USP17L7 USP17L4 USP17L2 USP17L8

6.08e-0635118421239494
Pubmed

A human MAP kinase interactome.

CASP8AP2 HIVEP1 SYNE1 ERBIN ABLIM1 DST PRKACA PRKCE MGA COPS5

6.57e-064861181020936779
Pubmed

The deubiquitinating enzyme USP17 blocks N-Ras membrane trafficking and activation but leaves K-Ras unaffected.

USP17L7 USP17L4 USP17L2 USP17L8

6.82e-0636118420147298
Pubmed

Ubiquitin hydrolase Dub3 promotes oncogenic transformation by stabilizing Cdc25A.

USP17L7 USP17L4 USP17L2 USP17L8

7.63e-0637118420228808
Pubmed

NEDD4 E3 ligase inhibits the activity of the Hippo pathway by targeting LATS1 for degradation.

WWOX SMURF1 SMURF2

8.19e-0612118324107629
Pubmed

Human and mouse proteases: a comparative genomic approach.

USP17L7 USP17L4 USP17L2 USP10 USP17L8

8.61e-0681118512838346
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

MBTPS1 TTC28 SYNE1 SMURF1 DGKB ERBIN FOCAD ABLIM1 LARGE1

1.10e-05407118912693553
Pubmed

The interaction between C5a and sphingosine-1-phosphate in neutrophils for antineutrophil cytoplasmic antibody mediated activation.

MBTPS1 C5

1.14e-052118225000985
Pubmed

Tumor necrosis factor alpha (TNF-alpha) activates Jak1/Stat3-Stat5B signaling through TNFR-1 in human B cells.

JAK1 TNFRSF1A

1.14e-052118211801527
Pubmed

The functions and regulation of Smurfs in cancers.

SMURF1 SMURF2

1.14e-052118231899247
Pubmed

Pediatric-type diffuse low-grade glioma with MYB/MYBL1 alteration: report of 2 cases.

MYB MYBL1

1.14e-052118236074655
Pubmed

The competing endogenous RNA network of CYP4Z1 and pseudogene CYP4Z2P exerts an anti-apoptotic function in breast cancer.

CYP4Z1 CYP4Z2P

1.14e-052118228236635
Pubmed

DNA binding and transactivation activity of A-myb, a c-myb-related gene.

MYB MYBL1

1.14e-05211827987850
Pubmed

Identification of a novel mammary-restricted cytochrome P450, CYP4Z1, with overexpression in breast carcinoma.

CYP4Z1 CYP4Z2P

1.14e-052118215059886
Pubmed

SMURF1 and SMURF2 in Progenitor Cells from Articular Cartilage and Meniscus during Late-Stage Osteoarthritis.

SMURF1 SMURF2

1.14e-052118233090007
Pubmed

Isomorphic diffuse glioma is a morphologically and molecularly distinct tumour entity with recurrent gene fusions of MYBL1 or MYB and a benign disease course.

MYB MYBL1

1.14e-052118231563982
Pubmed

JAK1 N-terminus binds to conserved Box 1 and Box 2 motifs of cytokine receptor common beta subunit but signal activation requires JAK1 C-terminus.

JAK1 CSF2RB

1.14e-052118216767694
Pubmed

[Polymorphism of TNF gene and CPOX gene in chemical industry workers].

CPOX TNFRSF1A

1.14e-052118222288185
Pubmed

Expression of mouse c-myb during embryonic development.

MYB MYBL1

1.14e-05211828570177
Pubmed

A single-center study of the clinicopathologic correlates of gliomas with a MYB or MYBL1 alteration.

MYB MYBL1

1.14e-052118231595312
Pubmed

Detecting MYB and MYBL1 fusion genes in tracheobronchial adenoid cystic carcinoma by targeted RNA-sequencing.

MYB MYBL1

1.14e-052118231028361
Pubmed

c-Myb regulates cell cycle-dependent expression of Erbin: an implication for a novel function of Erbin.

ERBIN MYB

1.14e-052118222880131
Pubmed

The 3'UTR of the pseudogene CYP4Z2P promotes tumor angiogenesis in breast cancer by acting as a ceRNA for CYP4Z1.

CYP4Z1 CYP4Z2P

1.14e-052118225701119
Pubmed

MYB and MYBL1 in adenoid cystic carcinoma: diversity in the mode of genomic rearrangement and transcripts.

MYB MYBL1

1.14e-052118229410490
Pubmed

IL-33 activates unprimed murine basophils directly in vitro and induces their in vivo expansion indirectly by promoting hematopoietic growth factor production.

CSF2RB IL33

1.14e-052118219684081
Pubmed

Adenoid cystic carcinoma of the Bartholin's gland is underpinned by MYB- and MYBL1- rearrangements.

MYB MYBL1

1.14e-052118238368814
Pubmed

Distribution of thyrotropin-releasing hormone (TRH) receptors in the brain of the ataxic mutant mouse, rolling mouse Nagoya.

CACNA1A TRHR

1.14e-05211829013814
Pubmed

Electrophysiology and GABA-immunocytochemistry in the vestibular nuclei of normal (C57BL/6J) and Leaner mutant mice.

CACNA1A KCNJ6

1.14e-05211828719615
Pubmed

Smurf2 induces ubiquitin-dependent degradation of Smurf1 to prevent migration of breast cancer cells.

SMURF1 SMURF2

1.14e-052118218927080
Pubmed

The second catalytic domain of protein tyrosine phosphatase delta (PTP delta) binds to and inhibits the first catalytic domain of PTP sigma.

PTPRD PTPRS

1.14e-05211829566880
Pubmed

Arrest of spermatogenesis and defective breast development in mice lacking A-myb.

MYB MYBL1

1.14e-05211829109487
Pubmed

Cul3-KLHL20 Ubiquitin Ligase Governs the Turnover of ULK1 and VPS34 Complexes to Control Autophagy Termination.

CASP8AP2 JMJD1C IVNS1ABP ABLIM1

2.01e-0547118426687681
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

TTC28 FRYL CUL7 USP10 ABLIM1 DST ALMS1 ANAPC1 TRAPPC9

2.25e-05446118924255178
Pubmed

Estrogen-regulated feedback loop limits the efficacy of estrogen receptor-targeted breast cancer therapy.

HIVEP1 SGIP1 SWT1 DDX60 CYP24A1 GRIK1 ERBIN IVNS1ABP TIGD2 C5 ALDH6A1

2.30e-056861181129987050
Pubmed

DUX is a non-essential synchronizer of zygotic genome activation.

USP17L7 USP17L4 USP17L2 USP17L8

2.57e-0550118431806660
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

CHAF1B TTC28 SYNE1 GRIK1 PREPL FOCAD JAK1 ABLIM1 FRY DST PTPRD KCNJ6 TNKS2 COPS5 SMURF2

3.09e-0512851181535914814
Pubmed

Ion channel mutations in mouse models of inherited neurological disease.

CACNA1A KCNJ6

3.42e-05311829562526
Pubmed

Induction of Jak/STAT signaling by activation of the type 1 TNF receptor.

JAK1 TNFRSF1A

3.42e-05311829510175
Pubmed

LAR receptor phospho-tyrosine phosphatases regulate NMDA-receptor responses.

PTPRD PTPRS

3.42e-053118231985401
Pubmed

Trans-synaptic adhesions between netrin-G ligand-3 (NGL-3) and receptor tyrosine phosphatases LAR, protein-tyrosine phosphatase delta (PTPdelta), and PTPsigma via specific domains regulate excitatory synapse formation.

PTPRD PTPRS

3.42e-053118220139422
Pubmed

Structural Basis for Auto-Inhibition of the NDR1 Kinase Domain by an Atypically Long Activation Segment.

STK38 FRYL

3.42e-053118229983373
Pubmed

The Smurf ubiquitin ligases regulate tissue separation via antagonistic interactions with ephrinB1.

SMURF1 SMURF2

3.42e-053118223475958
Pubmed

Intact synapse structure and function after combined knockout of PTPδ, PTPσ, and LAR.

PTPRD PTPRS

3.42e-053118233656439
Pubmed

Protease-activated receptor 2 sensitizes TRPV1 by protein kinase Cepsilon- and A-dependent mechanisms in rats and mice.

PRKACA PRKCE

3.42e-053118216793902
Pubmed

The myb gene family in cell growth, differentiation and apoptosis.

MYB MYBL1

3.42e-053118210378697
Pubmed

Cell signaling through the protein kinases cAMP-dependent protein kinase, protein kinase Cepsilon, and RAF-1 regulates amphotropic murine leukemia virus envelope protein-induced syncytium formation.

PRKACA PRKCE

3.42e-053118215741175
Pubmed

MYBL1 rearrangements and MYB amplification in breast adenoid cystic carcinomas lacking the MYB-NFIB fusion gene.

MYB MYBL1

3.42e-053118229149504
Pubmed

Smurf1 and Smurf2 mediated polyubiquitination and degradation of RNF220 suppresses Shh-group medulloblastoma.

SMURF1 SMURF2

3.42e-053118237537194
Pubmed

Bortezomib prevents oncogenesis and bone metastasis of prostate cancer by inhibiting WWP1, Smurf1 and Smurf2.

SMURF1 SMURF2

3.42e-053118225051198
Pubmed

Requirement of Smurf-mediated endocytosis of Patched1 in sonic hedgehog signal reception.

SMURF1 SMURF2

3.42e-053118224925320
Pubmed

Distribution of dopamine transporters in basal ganglia of cerebellar ataxic mice by [125I]RTI-121 quantitative autoradiography.

DST KCNJ6

3.42e-05311829460703
Pubmed

MST2- and Furry-mediated activation of NDR1 kinase is critical for precise alignment of mitotic chromosomes.

STK38 FRY

3.42e-053118219327996
Pubmed

Three lysine residues in the common β chain of the interleukin-5 receptor are required for Janus kinase (JAK)-dependent receptor ubiquitination, endocytosis, and signaling.

JAK1 CSF2RB

3.42e-053118221965659
Pubmed

Developmental expression of the cell adhesion molecule-like protein tyrosine phosphatases LAR, RPTPdelta and RPTPsigma in the mouse.

PTPRD PTPRS

3.42e-05311829784606
Pubmed

USF2 inhibits the transcriptional activity of Smurf1 and Smurf2 to promote breast cancer tumorigenesis.

SMURF1 SMURF2

3.42e-053118230244169
Pubmed

Down-regulation of Smad7 expression by ubiquitin-dependent degradation contributes to renal fibrosis in obstructive nephropathy in mice.

SMURF1 SMURF2

3.42e-053118215173588
Pubmed

Effects of thyrotropin releasing hormone on cerebellar mutant mice--a kinesiological comparison between rolling mouse Nagoya, weaver and reeler.

CACNA1A KCNJ6

3.42e-05311826811784
Pubmed

PIAS1 interacts with FLASH and enhances its co-activation of c-Myb.

CASP8AP2 MYB

3.42e-053118221338522
Pubmed

FLASH acts as a co-activator of the transcription factor c-Myb and localizes to active RNA polymerase II foci.

CASP8AP2 MYB

3.42e-053118218408764
Pubmed

Structural basis for LAR-RPTP/Slitrk complex-mediated synaptic adhesion.

PTPRD PTPRS

3.42e-053118225394468
Pubmed

SLC1A1, SLC16A9, and CNTN3 Are Potential Biomarkers for the Occurrence of Colorectal Cancer.

SLC16A9 CNTN3

3.42e-053118232566650
InteractionHUNK interactions

TTC28 ABLIM1 DST PTPRD PRKACA COPS5 TRAPPC9

2.69e-061091137int:HUNK
InteractionTNIK interactions

CACNA1A SYNE1 SMURF1 GATAD2B USP10 ABLIM1 DST PTPRD PTPRS PRKACA MGA

9.90e-0638111311int:TNIK
CoexpressionLAKE_ADULT_KIDNEY_C29_UNKNOWN_NOVEL_PT_CFH_POS_SUBPOPULATION_S2

PRUNE2 WWOX TTC28 SYNE1 DST TRAPPC9

2.57e-06861186M39248
CoexpressionGSE19941_LPS_VS_LPS_AND_IL10_STIM_IL10_KO_NFKBP50_KO_MACROPHAGE_UP

ST6GALNAC1 RAD52 ZFP90 SMURF1 CPOX ERBIN MSMB FRY

3.44e-061991188M8119
CoexpressionLAKE_ADULT_KIDNEY_C2_PODOCYTES

ADAMTS19 SGIP1 WWOX ERBIN FRY DST PTPRD LARGE1

5.48e-062121188M39221
CoexpressionGSE11057_EFF_MEM_VS_CENT_MEM_CD4_TCELL_DN

HIVEP1 PHGDH ABLIM1 FAM13A PTPRS MYB TBL1X

2.44e-051891187M3112
CoexpressionGSE3982_DC_VS_EFF_MEMORY_CD4_TCELL_DN

SYNE1 PEX3 STK38 JAK1 FRY GGPS1 MYBL1

3.18e-051971187M5475
CoexpressionGSE11057_NAIVE_VS_EFF_MEMORY_CD4_TCELL_UP

HIVEP1 TTC28 PHGDH ABLIM1 MGA MYB TBL1X

3.28e-051981187M3104
CoexpressionGSE2770_IL12_VS_TGFB_AND_IL12_TREATED_ACT_CD4_TCELL_6H_DN

PRUNE2 MAP2K4 DDX60 USP10 TNFRSF1A SMURF2 TRAPPC9

3.39e-051991187M6060
CoexpressionGSE1432_1H_VS_6H_IFNG_MICROGLIA_DN

DDX60 STK38 SMURF1 NBN USP10 CSF2RB GGPS1

3.50e-052001187M3411
CoexpressionMADAN_DPPA4_TARGETS

USP17L7 USP17L4 USP17L2 RNF17 USP17L8

4.42e-05861185MM1312
CoexpressionLAKE_ADULT_KIDNEY_C14_DISTAL_CONVOLUTED_TUBULE

WWOX IVNS1ABP ABLIM1 DST SLC12A3 TRAPPC9 TBL1X

4.49e-052081187M39233
CoexpressionBROWNE_HCMV_INFECTION_48HR_DN

CACNA1A PRUNE2 RAD52 RFX1 PTPRD ALMS1 FADS2 ALDH6A1 EPB42 MYB

6.68e-0548211810M12144
CoexpressionTABULA_MURIS_SENIS_BRAIN_NON_MYELOID_NEURON_AGEING

CACNA1A WWOX STK38 FRYL SLC30A4 PHGDH FOCAD USP10 PSTK C1orf198 PTPRS KCNJ6 PPA2 PRKCE

1.01e-0495411814MM3689
CoexpressionHOSHIDA_LIVER_CANCER_SURVIVAL_DN

RAD52 AKR1A1 CPOX DST C5

1.62e-041131185M5451
CoexpressionONDER_CDH1_TARGETS_2_UP

PRUNE2 CADM3 SYNE1 KCNJ6 ALDH6A1 TBL1X MYBL1

1.68e-042571187M13867
CoexpressionGSE40274_FOXP3_VS_FOXP3_AND_SATB1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN

STK38 PHGDH FOCAD ABLIM1 GGPS1 MYB

1.68e-041801186M9145
CoexpressionTAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_3D_UP

ST6GALNAC1 TTC28 DDX60 DST PTPRD ALDH1A1

1.84e-041831186M6670
CoexpressionMEK_UP.V1_DN

DDX60 JMJD1C MSMB ABLIM1 MYB MYBL1

2.52e-041941186M2724
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN

MAP2K4 HIVEP1 PEX3 NBN FRYL DST SMURF2 TBL1X MYBL1

2.66e-044661189M13522
CoexpressionGSE17974_0.5H_VS_72H_IL4_AND_ANTI_IL12_ACT_CD4_TCELL_UP

MBTPS1 HIVEP1 STK38 SMURF1 JMJD1C PSTK

2.67e-041961186M4244
CoexpressionGSE16755_CTRL_VS_IFNA_TREATED_MAC_UP

UVSSA AKR1A1 MOB3A TIGD2 FAM13A GGPS1

2.67e-041961186M3668
CoexpressionERBB2_UP.V1_DN

DDX60 CPOX MSMB ABLIM1 MYB MYBL1

2.74e-041971186M2635
CoexpressionGSE3982_EOSINOPHIL_VS_EFF_MEMORY_CD4_TCELL_DN

CASP8AP2 PEX3 STK38 FRYL AKR1A1 EPB42

2.81e-041981186M5417
CoexpressionGSE7460_FOXP3_MUT_VS_WT_ACT_TCONV_DN

SLC30A4 FRY C1orf198 HDAC10 ALDH6A1 TBL1X

2.81e-041981186M5701
CoexpressionGSE22886_NAIVE_TCELL_VS_NKCELL_DN

FRYL IVNS1ABP TNFRSF1A SMURF2 TBL1X UEVLD

2.81e-041981186M4415
CoexpressionGSE19941_UNSTIM_VS_LPS_AND_IL10_STIM_IL10_KO_MACROPHAGE_UP

RAD52 ZFP90 SMURF1 MOB3A CNTN3 TNFRSF1A

2.89e-041991186M8107
CoexpressionGSE19941_UNSTIM_VS_LPS_STIM_IL10_KO_MACROPHAGE_UP

RAD52 SMURF1 MOB3A CNTN3 ALDH1A1 TNFRSF1A

2.89e-041991186M8105
CoexpressionGSE28737_FOLLICULAR_VS_MARGINAL_ZONE_BCELL_UP

MBTPS1 SGIP1 MCTP1 PPA2 PRKACA HDAC10

2.89e-041991186M9351
CoexpressionGSE10273_HIGH_VS_LOW_IL7_TREATED_IRF4_8_NULL_PRE_BCELL_DN

TTC28 STK38 SMURF1 ERBIN TNKS2 SMURF2

2.89e-041991186M316
CoexpressionGSE14350_TREG_VS_TEFF_UP

SYNE1 STK38 ERBIN GATAD2B HDAC10 SMURF2

2.89e-041991186M3417
CoexpressionGSE21546_WT_VS_ELK1_KO_DP_THYMOCYTES_DN

USP17L2 FOCAD C1orf198 PRKACA COPS5 NXPH4

2.89e-041991186M7527
CoexpressionGSE36078_UNTREATED_VS_AD5_INF_IL1R_KO_MOUSE_LUNG_DC_UP

TRHR NBN GATAD2B TIGD2 TRPM1 MYB

2.97e-042001186M9301
CoexpressionGSE15324_NAIVE_VS_ACTIVATED_ELF4_KO_CD8_TCELL_DN

ST6GALNAC1 PREPL USP10 MCTP1 VSTM5 UEVLD

2.97e-042001186M3527
CoexpressionGSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_1H_UP

NPHP1 PHGDH CSF2RB TNFRSF1A TNKS2 CDH5

2.97e-042001186M9635
CoexpressionGSE5589_LPS_VS_LPS_AND_IL10_STIM_IL6_KO_MACROPHAGE_180MIN_DN

SCFD2 PHGDH FOCAD PTPRS PRKCE COPS5

2.97e-042001186M6624
CoexpressionGSE27786_LSK_VS_NKTCELL_UP

NPHP1 NBN CUL7 MCTP1 PPA2 COPS5

2.97e-042001186M4754
CoexpressionGSE15735_CTRL_VS_HDAC_INHIBITOR_TREATED_CD4_TCELL_12H_DN

DDX60 STK38 SMURF1 PIWIL4 FOCAD JAK1

2.97e-042001186M7157
CoexpressionGSE21670_UNTREATED_VS_IL6_TREATED_STAT3_KO_CD4_TCELL_UP

C5 ALDH1A1 TNFRSF1A MYB TBL1X UEVLD

2.97e-042001186M7457
CoexpressionGSE21670_STAT3_KO_VS_WT_CD4_TCELL_TGFB_IL6_TREATED_DN

STK38 MCTP1 C5 ALDH1A1 TNFRSF1A TBL1X

2.97e-042001186M7453
CoexpressionKAPOSI_LIVER_CANCER_MET_DN

ALDH1A1 ALDH6A1

2.98e-0461182M2184
CoexpressionGSE38697_LIGHT_ZONE_VS_DARK_ZONE_BCELL_DN

SLC16A9 CYP24A1 GRIK1 CNTN3 ALDH1A1

3.11e-041301185M9010
ToppCellrenal_cortex_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

WWOX TTC28 JMJD1C PTPRD PRKCE TRAPPC9 LARGE1

8.17e-071921187e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCellMesenchymal-matrix_fibroblast_1_cell|World / Lineage, Cell type, age group and donor

VGLL3 SGIP1 TTC28 DST PTPRD PTPRS CNTN3

8.45e-071931187acad568621ed677031797b8c2e34dafea798d681
ToppCellE18.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CASP8AP2 MAP2K4 PIWIL4 ALMS1 SERPIND1 IL33

4.86e-061631186d2fcd6f561748f7d29a051c504f016952ba32d0f
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CACNA1A NWD1 SLC16A9 CYP24A1 TRPM1 ALDH6A1

5.59e-0616711863edb0570e583bb527165bcd8a4c25a042054043b
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m-Epithelial-nan|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRUNE2 SLC12A3 C10orf62 TRPM1 IL33 MYB

7.30e-0617511869a96794df049d8228fea57c1584c160191d36b56
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PRUNE2 CADM3 SGIP1 DST CNTN3 EPB42

8.85e-061811186b116c68393d8836bac080f81a8fcbeb52e0403e7
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS19 SGIP1 FRY DST PTPRD LARGE1

1.00e-0518511869197f074e769d54031ec41abfc65fcc0c6552c7e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS19 SGIP1 FRY DST PTPRD LARGE1

1.00e-051851186ce7d62394b09c26ca65b8cdb280afec5e25bbb62
ToppCell3'_v3-blood-Hematopoietic_progenitors-Progenitor_Erythro-Mega|blood / Manually curated celltypes from each tissue

SGIP1 SLC16A9 FADS2 ALDH1A1 EPB42 MYB

1.03e-05186118659c115bbbb4bca4ad80be1809d8a0422b8438ea3
ToppCellCOVID-19-Fibroblasts-Airway_smooth_muscle|COVID-19 / group, cell type (main and fine annotations)

PRUNE2 VGLL3 TTC28 DGKB FRY DST

1.07e-051871186464a0c3b92b778911b5f9cd73642e09e3472063a
ToppCellNS-critical-d_16-33-Epithelial-Secretory-diff|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ST6GALNAC1 SLC16A9 MSMB ABLIM1 ALDH1A1 IL33

1.24e-05192118602b11233b4da2d85b96498b3c6e22e3a31b3d049
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1A TTC28 FRYL DST TNKS2 MGA

1.35e-0519511863e519cffa6144a62b06124642a14c9ff39b76554
ToppCellSomatosensory_Cortex_(S1)-Neuronal|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CACNA1A SYNE1 PREPL FOCAD FRY PRKCE

1.47e-051981186c01091ef18e096d792ea2a7a715764a5b215355f
ToppCellprimary_auditory_cortex_(A1C)-Neuronal|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CACNA1A SYNE1 PREPL FOCAD FRY PRKCE

1.47e-0519811866d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CACNA1A SYNE1 DGKB FOCAD FRY PRKCE

1.47e-0519811864ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCellParenchymal-NucSeq|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations

WWOX TTC28 SMURF1 PTPRD PRKCE TRAPPC9

1.47e-0519811861996373bdccc55aac347d349bd22f6aad6d0c668
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Macroglial-oligodendrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TPRN CPOX ERBIN PHGDH PTPRD IL33

1.52e-05199118667d8c7e5356f5d409d4f98e8338cf6c499fd7aee
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial-Vein|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

CADM3 ABLIM1 FRY DST CDH5 IL33

1.56e-0520011867eb366b2c5394af7c77650bde6261e7dac67154e
ToppCellNeuronal|World / cells hierarchy compared to all cells using T-Statistic

CACNA1A SYNE1 PREPL FOCAD FRY PRKCE

1.56e-05200118648d801219bc771d6c7e151dc88ca4c179988de85
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PRUNE2 SLC16A9 AKR1A1 PTPRD ALDH1A1 ALDH6A1

1.56e-052001186e118d5e6e5d5bb808877a6667668c36f21afad5b
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Macroglial-oligodendrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TPRN CPOX ERBIN PHGDH PTPRD IL33

1.56e-052001186e5b4821fff40566c4a7dc3f74a14e27eb06b165d
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PRUNE2 SLC16A9 AKR1A1 PTPRD ALDH1A1 ALDH6A1

1.56e-052001186234e5a927eec0e235226586451ba3754c8a14169
ToppCell390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_3|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

NPHP1 PIWIL4 DNAJC28 ANKRD1 IL33

4.82e-05149118568661c8facfb638560bb2e2c20d509941286dacb
ToppCell10x5'-Liver-Myeloid_Mac-Intestinal_macrophages|Liver / Manually curated celltypes from each tissue

PRUNE2 SLC16A9 DST CDH5 LARGE1

6.00e-0515611859a897fc79c4fae94c5f2e9012d65297f9225e5e3
ToppCell3'-Distal_airway-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ST6GALNAC1 CYP24A1 RNF17 CNTN3 IL33

6.56e-0515911851baf0eaf9684668146a63192e77eec6c3c7a37f8
ToppCellPND10-Immune-Immune_Myeloid-Granulocytic-Mast|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PRUNE2 MCTP1 DNAJC28 CSF2RB MYB

6.76e-0516011856393e3d5c5c8176c93aecd89b313bd054a00d474
ToppCellPND10-Immune-Immune_Myeloid-Granulocytic-Mast-Mast_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PRUNE2 MCTP1 DNAJC28 CSF2RB MYB

6.76e-0516011852065938e944eb99478fd8132c2c03adeaee6d447
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Neural-neural_cell-Schwann_Cell_/_Neural|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CADM3 VGLL3 DGKB C1orf198 TRPM1

6.96e-0516111857d1bc73f4c82465b3f489d6737048b0cd54f22cf
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Neural-neural_cell-Schwann_Cell_/_Neural-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CADM3 VGLL3 DGKB C1orf198 TRPM1

6.96e-051611185410eef62c83c704cbfc5a1b643c4db11bbdcd81f
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Neural|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CADM3 VGLL3 DGKB C1orf198 TRPM1

6.96e-05161118571022485da6754a2b57b4c3e758e3de4c95cc292
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligoastrocytoma|TCGA-Brain / Sample_Type by Project: Shred V9

ABLIM1 DST PTPRD CNTN3 ALDH6A1

6.96e-051611185347edb0de10850b7d16c40945751033289289c9b
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Neural-neural_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CADM3 VGLL3 DGKB C1orf198 TRPM1

6.96e-05161118559ae8a7c9a04ecaa335b8064852a5a91a21780bd
ToppCellAdult-Epithelial-lung_goblet_cell-D175|Adult / Lineage, Cell type, age group and donor

ST6GALNAC1 SLC16A9 MSMB CNTN3 IL33

7.60e-0516411856e6aedb61f8e195d52e028fdda750a29bb14e57e
ToppCellfacs-Liver-Hepatocytes-24m-Myeloid-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NPHP1 CHAF1B ZFP90 RNF17 ALMS1

8.05e-05166118503a47b8687f54955e84df1edcb230db332c4ca8f
ToppCellClub_cells-IPF_03|World / lung cells shred on cell class, cell subclass, sample id

ST6GALNAC1 CYP24A1 MSMB VSTM5 NXPH4

8.28e-051671185dbdaaeb3bd9139cb008d9fe24ec031fc5628f136
ToppCellfacs-Marrow-T_cells-18m-Hematologic-MPP_Fraction_B_+_C|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1A SGIP1 C1orf198 FADS2 QRSL1

8.75e-0516911852a35846b0e0be0a19a5a04a86cbd72ce65257c8a
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SCFD2 ZC2HC1C DNAH1 SLFN12L FAM13A

9.00e-051701185adb625124832b0786a590e8f75b61e7263a1e0d4
ToppCellCOVID-19-kidney-PEC|kidney / Disease (COVID-19 only), tissue and cell type

PRUNE2 CADM3 TTC28 SYNE1 FRY

9.51e-05172118536a96714a0eb6ac438648135336c9791881ddadb
ToppCellCTRL-Lymphoid-pDC|Lymphoid / Disease state, Lineage and Cell class

MCTP1 SLC12A3 CSF2RB PTPRS MYB

1.00e-041741185ff4315e9fad198cc323fc987deb8652da137cf98
ToppCellB_cells-pDCs|B_cells / Immune cells in Kidney/Urine in Lupus Nephritis

DST MCTP1 SLC12A3 PTPRS MYB

1.06e-041761185ce757de9e09a225f3f96433f103f43619b0e0dda
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PRUNE2 SGIP1 SYNE1 TBL1X LARGE1

1.06e-041761185327a3e81b724252e36d786de92a3ffd721ea6d7b
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PRUNE2 SLC16A9 CYP24A1 DGKB PTPRD

1.06e-0417611851595dbeee336a81e581325d63208ec6262664ee9
ToppCellfacs-Spleen-nan-3m-Lymphocytic-CD8-positive,_alpha-beta_T_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STK38 JAK1 ABLIM1 TRPM1 MYB

1.09e-041771185ac0cf03e2a1baf84db3ae245d59bbc6ae52c13be
ToppCellAdult-Epithelial-club_cell-D122|Adult / Lineage, Cell type, age group and donor

ST6GALNAC1 CHAF1B PTPRD CNTN3 ALDH1A1

1.12e-04178118535a2e3ba98b6f857dbb79cf8ddb4846ddcda6c17
ToppCelldroplet-Liver-LIVER_NPC-30m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CASP8AP2 TPRN CUL7 MCTP1 MGA

1.15e-041791185025d414ec88d5680d99c8173e70ee3bb0b694f74
ToppCellAdult-Epithelial-lung_goblet_cell|Adult / Lineage, Cell type, age group and donor

ST6GALNAC1 SLC16A9 MSMB CNTN3 ALDH1A1

1.15e-0417911851fc1f252ca943a2f649d1e627f56acbf15f8e058
ToppCellCOVID-19-Heart-EC_2|COVID-19 / Disease (COVID-19 only), tissue and cell type

FRYL ABLIM1 MCTP1 CDH5 IL33

1.15e-0417911852a53d94f6c30bf887dfe88f1693ea057218c852d
ToppCellPBMC-Convalescent-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_4|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TTI2 SMURF1 MCTP1 ALDH1A1 UEVLD

1.21e-0418111852b9b460239d67fd480cee60820cdb306109d3567
ToppCellPBMC-Convalescent-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_4|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

TTI2 SMURF1 MCTP1 ALDH1A1 UEVLD

1.21e-0418111852a1aa4a0ec7bc367857beaff543135e4345c835b
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PRUNE2 SLC16A9 CYP24A1 DGKB PTPRD

1.24e-0418211854a9c13932e7163fd37a3dcc4c6ca3bbea5372459
ToppCell3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

WWOX MSMB KPNA7 C10orf62 ALDH1A1

1.24e-041821185818b5155ec81f0059048d6070a108116ecd72e3c
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS19 SGIP1 FRY PTPRD LARGE1

1.27e-0418311853c516fe5083f02bad1f464ed284010b4131a833c
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS19 SGIP1 FRY PTPRD LARGE1

1.27e-0418311859c2689d76fc6d30f5ab093428aa669d0a98953cf
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Macroglial-oligodendrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TPRN GRIK1 CPOX PTPRD IL33

1.27e-041831185eb1f1dd12d1e4f1a7029b5396baada23f7c971ff
ToppCell3'_v3-bone_marrow-Hematopoietic_Erythro-Mega-Erythrocytic_early|bone_marrow / Manually curated celltypes from each tissue

SLC16A9 FADS2 ALDH1A1 EPB42 MYB

1.27e-041831185d43ba3fbbd9132125fa2b7ea0891a2c577974f14
ToppCelldroplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l1-41|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CADM3 ADAMTS19 ZFP90 VSTM5 IL33

1.27e-04183118507ca2786e62eca9feecf5e54a11864a960f7641a
ToppCellControl-Endothelial_cells-Pulmonary_venous_endothelial_cells|Control / group, cell type (main and fine annotations)

CADM3 ABLIM1 MCTP1 CDH5 IL33

1.27e-04183118546be9f96755c7b65aeac061d95d15abeb6466034
ToppCelldroplet-Kidney-nan-18m-Epithelial-Epcam____kidney_proximal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP24A1 PTPRD FAM13A C2orf80 ALDH6A1

1.30e-041841185c86ed59fed687cdaaf7e9c4418d2e3e2c4111cca
ToppCelldroplet-Kidney-nan-18m-Epithelial-kidney_proximal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP24A1 PTPRD FAM13A C2orf80 ALDH6A1

1.30e-0418411857c256bcfa07c5ff55aad0833e8712b0456b5832b
ToppCellLV-15._Ventricular_Cardiomyocyte_III|LV / Chamber and Cluster_Paper

ABLIM1 FRY DST ANKRD1 LARGE1

1.30e-041841185ab7a1620c14a9d9b6be1b47c559931e345e9eef8
ToppCellCOVID-19-Endothelial_cells-Arterial_endothelial_cells|COVID-19 / group, cell type (main and fine annotations)

TTC28 ABLIM1 MCTP1 CDH5 IL33

1.30e-0418411850f19494789f38ab1a420545e15e748ca7eb345c3
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS19 SGIP1 FRY PTPRD LARGE1

1.30e-0418411857294b379ce4cb8fa75e432559082f93cd106aaf5
ToppCelldroplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l20-1|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CADM3 ADAMTS19 ABLIM1 C2orf80 IL33

1.34e-041851185d5f5866924648a3c14e2596218fd548a31777aa3
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal-interneuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1A PRUNE2 CADM3 MCTP1 PRKCE

1.37e-041861185d1d01ce46e62944aa9864eda47e8401b5f0d2bdc
ToppCell3'_v3-bone_marrow-Hematopoietic_Erythro-Mega|bone_marrow / Manually curated celltypes from each tissue

SLC16A9 FADS2 ALDH1A1 EPB42 MYB

1.37e-0418611859ff3c30b1728707bb8f9422941333fe3b2c430f4
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

CYP4Z1 ABLIM1 C1orf198 DST ANKRD1

1.41e-041871185d4b0afd9b92c47c8aa348bbd1af7eb54c3d478f2
ToppCellASK454-Epithelial-Type_1|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq

ST6GALNAC1 ABLIM1 C1orf198 DST ANKRD1

1.44e-04188118513f8ce8f24ac7d7ed87f4ae3b8f4096de29383c2
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ST6GALNAC1 SLC16A9 MSMB ABLIM1 ALDH1A1

1.44e-0418811855901b276f2379abf486b8285957277e95f08464e
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PRUNE2 SGIP1 SYNE1 TBL1X LARGE1

1.44e-04188118563a4b25a0a6e05f80f1a6dd91b817f3cf49e6b68
ToppCellCOPD-Multiplet-Multiplet|World / Disease state, Lineage and Cell class

SYNE1 CYP4Z2P SLFN12L ABLIM1 MYBL1

1.44e-041881185186fe1ea328c942910190a4240262c0d8642ea3b
ToppCell21-Trachea-Epithelial-Neuroendocrine|Trachea / Age, Tissue, Lineage and Cell class

CACNA1A PRUNE2 SGIP1 DGKB KCNJ6

1.44e-041881185e78d4f7a5d28c77503cb041ff585d13df4c88bd2
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

STK38 SLFN12L ABLIM1 FAM13A MYBL1

1.48e-0418911855a9e2ca9a9ee2dc37ab9147a902115a9f1a80169
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

VGLL3 SGIP1 SYNE1 IL33 LARGE1

1.52e-0419011851121eb607a984c59fbffe7220837fc178745aa55
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

VGLL3 SGIP1 SYNE1 IL33 LARGE1

1.52e-041901185048b581e3f7ea9fc2f87c0532974bba85c7292c2
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Myeloid-Macrophage|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

NBN MCTP1 CSF2RB ALDH1A1 TNFRSF1A

1.52e-041901185e1c02fe6fa43a36381cb9f02569fa9b1c5f5efdc
ToppCellrenal_medulla_nuclei-Adult_normal_reference|renal_medulla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

WWOX JMJD1C FRY PRKCE TRAPPC9

1.52e-041901185f1363f7806cfc4f14fbc1b0e8dac2de813a88eee
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Myeloid-Macrophage-macrophage,_alveolar|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

NBN MCTP1 CSF2RB ALDH1A1 TNFRSF1A

1.52e-0419011856de15ec88426fbf52acb0a8371f82cf03b6a6237
ToppCellfacs-Lung-24m-Mesenchymal-fibroblast-alveolar_fibroblast|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

VGLL3 PTPRD FAM13A FADS2 ALDH1A1

1.55e-04191118580484d39f34703a33b9bac09826b7a526e883cab
ToppCellfacs-Marrow-KLS-18m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PHGDH USP10 FADS2 ALDH1A1 MYB

1.55e-04191118551327ba28b2e3052087fa0fc9b7c0339dc09a1e3
ToppCellfacs-Lung-24m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l49|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

VGLL3 PTPRD FAM13A FADS2 ALDH1A1

1.55e-0419111855c4e4e9de14edfae072a2a2882220a31bebf51b2
ToppCelldroplet-Marrow-BM-1m-Lymphocytic-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PHGDH IVNS1ABP PTPRS CDH5 MYB

1.55e-0419111854187f31ec399b4c7c3608e94e3c32b7a54b1c3d4
ToppCelldroplet-Marrow-BM-1m-Lymphocytic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PHGDH IVNS1ABP PTPRS CDH5 MYB

1.55e-0419111858e8bc200524a44ebe132f823ab7c15dac65d4952
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Myeloid-Macrophage-macrophage,_alveolar-Macro_c2-CCL3L1|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

NBN MCTP1 CSF2RB ALDH1A1 TNFRSF1A

1.55e-04191118581f77bf497b8e0ae0affe7d5f4f00446547229f6
ToppCellfacs-Brain_Non-Myeloid-Cortex_-18m-Macroglial-oligodendrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TPRN CPOX PHGDH PTPRD IL33

1.59e-0419211853916de42b9a626b5679ca98057d6e69f146b2810
ToppCell5'-GW_trimst-1.5-SmallIntestine-Neuronal-Glial_immature-Glia_1_(DHH+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VGLL3 C1orf198 DST FADS2 ALDH1A1

1.63e-0419311853ea6b103e35bbb276e95301999618558fa3e38b1
ToppCellnucseq|World / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

WWOX JMJD1C PRKCE TRAPPC9 EPB42

1.63e-041931185779276e775cb2492e8dd36436295a536084a6415
ToppCellfacs-Brain_Non-Myeloid-Cortex_-18m-Macroglial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TPRN CPOX PHGDH PTPRD IL33

1.63e-041931185e1eee31db283aa49568b50f2ddd99f0054c99fbe
ToppCellPCW_13-14-Endothelial-Endothelial_mature-endo_venous_(13)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

CADM3 MCTP1 CSF2RB CDH5 IL33

1.63e-04193118584d1c1b7d3a1cb80f175527e3c89a2c3da7657f7
ToppCellhuman_hepatoblastoma|World / Sample and Cell Type and Tumor Cluster (all cells)

ADAMTS19 HIVEP1 WWOX TTC28 ERBIN

1.63e-041931185e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCell3'-Child04-06-SmallIntestine-Epithelial-goblet-Goblet_cell|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ST6GALNAC1 PRUNE2 FRYL FRY DST

1.67e-04194118549cc5f5de4380302100e8cd937f08abe317ac75e
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

VGLL3 SGIP1 TTC28 DST CNTN3

1.67e-041941185011e14d9ed1393275f892060e7708ffadcd0767f
ToppCell3'-Child04-06-SmallIntestine-Epithelial-goblet|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ST6GALNAC1 PRUNE2 FRYL FRY DST

1.67e-041941185fb935df966c451e659b8bde281f8aebcb632f6cf
ToppCellfacs-Brain_Non-Myeloid-Cortex_-18m-Macroglial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TPRN CPOX PHGDH PTPRD IL33

1.67e-04194118561b59f8e2c68851d827b058cf03904f8125e8047
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

SCFD2 TTC28 SLFN12L DST PTPRD

1.67e-041941185b1bb0f846d2865efdd9bc8842b16b9d069785882
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

VGLL3 SGIP1 SYNE1 PTPRD PTPRS

1.67e-04194118560622bd2f75bfe4c37f721cb12f03dab33f2f58d
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

VGLL3 SGIP1 DST PTPRD CNTN3

1.67e-04194118535f132cc38ac133be01834ed0946188aa0757eb4
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Scavenging_endothelial-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ST6GALNAC1 IVNS1ABP ABLIM1 FRY CDH5

1.67e-041941185ea5e1bc8d9e27cabfe1fb833ca47ec0893593b12
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Scavenging_endothelial|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ST6GALNAC1 IVNS1ABP ABLIM1 FRY CDH5

1.67e-041941185cceb7c88492bb6cd531e1c2651638da1ddf30931
ToppCellCOVID-19-Heart-CM_2|Heart / Disease (COVID-19 only), tissue and cell type

ABLIM1 FRY DST ANKRD1 LARGE1

1.71e-04195118575fc81bddb246dca3b437fb60827b1d4fe416405
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

SGIP1 TTC28 SLFN12L DST PTPRD

1.71e-0419511850e55fa5b3cbeb7baee3d4ac272a3bf80381ec937
ComputationalGenes in the cancer module 206.

MBTPS1 HIVEP1 GRIK1 USP10 FADS2 CNTN3 EPB42

6.67e-05154717MODULE_206
Druglactobionic acid

WWOX SYNE1 CNTN3 SERPIND1

3.70e-06211174CID000007314
DrugAG-013608 [351320-38-2]; Up 200; 10uM; MCF7; HT_HG-U133A

NPHP1 SYNE1 CYP24A1 ZC2HC1C MCTP1 DNAJC28 SNAPC2 TBL1X

8.00e-0619611786435_UP
DrugHyoscyamine (L) [101-31-5]; Down 200; 13.8uM; PC3; HT_HG-U133A

SMURF1 CUL7 ALMS1 FAM13A PTPRS ALDH6A1 NXPH4 LARGE1

8.62e-0619811785099_DN
DiseaseR-6-hydroxywarfarin measurement

NWD1 WWOX DDX60 UVSSA PTPRD TRAPPC9

6.12e-061141166EFO_0803327
Diseaseprimary ovarian insufficiency (implicated_via_orthology)

USP17L7 USP17L4 USP17L2 USP17L8

3.26e-05461164DOID:5426 (implicated_via_orthology)
Diseaseurate measurement, bone density

RAD52 CASP8AP2 CHAF1B WWOX TTC28 SYNE1 ERBIN PREPL DNAH1 PTPRD CSF2RB

3.41e-0561911611EFO_0003923, EFO_0004531
Diseasesunburn

SGIP1 UVSSA FAM13A PRKCE TRPM1

3.96e-05961165EFO_0003958
DiseaseAdenoid Cystic Carcinoma

ERBIN JMJD1C MGA MYB MYBL1

4.81e-051001165C0010606
Diseaseeosinophil count

ADAMTS19 CHAF1B ZFP90 HIVEP1 WWOX SMURF1 CPOX JAK1 SLFN12L KPNA7 TIGD2 CSF2RB ANAPC1 FADS2 TNFRSF1A IL33 MYB

7.21e-05148811617EFO_0004842
DiseaseAlcoholic Intoxication, Chronic

SGIP1 GRIK1 AKR1A1 ANAPC1 KCNJ6 ALDH1A1 CDH5

9.47e-052681167C0001973
Diseasemultiple sclerosis

WWOX TTC28 CYP24A1 PHGDH JAK1 MCTP1 CSF2RB PPA2 TNFRSF1A MYB

1.22e-0459411610MONDO_0005301
Diseasearachidonic acid measurement

CACNA1A VGLL3 FADS2

1.28e-04251163EFO_0006808
Diseasecongenital heart disease (implicated_via_orthology)

USP17L7 USP17L4 USP17L2 USP17L8

1.61e-04691164DOID:1682 (implicated_via_orthology)
Diseasedaytime rest measurement

CACNA1A WWOX TRHR PREPL FOCAD FADS2 QRSL1

1.71e-042951167EFO_0007828
Diseaselung non-small cell carcinoma (is_implicated_in)

RAD52 MAP2K4 CYP24A1 JAK1 TNFRSF1A

2.28e-041391165DOID:3908 (is_implicated_in)
DiseaseAlcoholic Intoxication

GRIK1 AKR1A1 ALDH1A1

2.70e-04321163C0001969
DiseaseHereditary Autoinflammatory Diseases

NLRC4 TNFRSF1A

3.18e-0471162C0751422
Diseaseabnormal vaginal discharge smell

CYP24A1 KCNJ6

3.18e-0471162EFO_0009408
Disease10-undecenoate 11:1n1 measurement

CYP4Z1 CYP4Z2P

3.18e-0471162EFO_0021099
DiseaseFEV/FEC ratio

SCFD2 MAP2K4 CHAF1B DGKB AKR1A1 TEKT5 JMJD1C DST FAM13A ANAPC1 PRKCE MGA SMURF2 IL33

3.36e-04122811614EFO_0004713
Diseaseamino acid measurement

ADAMTS19 WWOX SYNE1 SMURF1 DGKB C1orf198 ALMS1 PRKCE C5 TNKS2

3.52e-0467811610EFO_0005134
Diseaseresponse to risperidone

PPA2 HMGXB3 TRPM1

4.52e-04381163GO_0097336
Diseasetestosterone measurement

SCFD2 VGLL3 WWOX SLC16A9 TTC28 TPRN CYP24A1 DGKB JMJD1C NLRC4 ANAPC1 PPA2 TNKS2 TBL1X

4.89e-04127511614EFO_0004908
Diseaserectum cancer (is_implicated_in)

CYP24A1 NBN

5.42e-0491162DOID:1993 (is_implicated_in)
Diseaselymphocyte count

NWD1 HIVEP1 WWOX TTC28 NBN JMJD1C FOCAD JAK1 SLFN12L ALMS1 ANAPC1 PPA2 FADS2 TNFRSF1A MYB

6.26e-04146411615EFO_0004587
Diseasebreast carcinoma

SCFD2 VGLL3 WWOX TTC28 GRIK1 AKR1A1 TEKT5 JMJD1C PHGDH PTPRD SLC12A3 PPA2

6.88e-04101911612EFO_0000305
Diseaseeosinophil percentage of leukocytes

ZFP90 WWOX JMJD1C JAK1 SLFN12L CSF2RB ANAPC1 FADS2 IL33 MYB

7.38e-0474611610EFO_0007991
Diseasephosphatidylcholine 32:0 measurement

PTPRD FADS2

8.23e-04111162EFO_0010372
Diseaseopen-angle glaucoma

SCFD2 CHAF1B STK38 DST FAM13A

9.68e-041911165EFO_0004190
Diseasearachidonoylcarnitine (C20:4) measurement

SLC16A9 FADS2

9.86e-04121162EFO_0800544
Diseasesurvival time, breast carcinoma

C2orf80 TBL1X

1.16e-03131162EFO_0000305, EFO_0000714
Diseaseundecenoylcarnitine (C11:1) measurement

SLC16A9 CYP4Z2P

1.16e-03131162EFO_0800588
Diseasedihomo-linolenoylcarnitine (C20:3n3 or 6) measurement

SLC16A9 FADS2

1.16e-03131162EFO_0800547
DiseaseFVC change measurement, response to placebo

DGKB KCNJ6

1.16e-03131162EFO_0008344, EFO_0010339
DiseaseBardet-Biedl Syndrome

NPHP1 ALMS1

1.16e-03131162C0752166
Diseaselymphocyte measurement

TTC28 JMJD1C SLFN12L ANAPC1

1.19e-031171164EFO_0803546
Diseasehair morphology measurement

WWOX CPOX MCTP1

1.27e-03541163EFO_0007821
Diseasephosphatidylcholine 36:5 measurement

ADAMTS19 FADS2

1.35e-03141162EFO_0010383
Diseasecolorectal cancer (is_implicated_in)

RAD52 MAP2K4 CYP24A1 JAK1

1.35e-031211164DOID:9256 (is_implicated_in)
DiseaseEczema

TTC28 CYP24A1 MSMB JAK1 CSF2RB ANAPC1

1.45e-033101166HP_0000964
Diseaseplatelet measurement

STK38 JMJD1C SLFN12L FADS2 TNFRSF1A MYB

1.57e-033151166EFO_0005036
Diseasemetabolite measurement

WWOX SLC16A9 AKR1A1 PHGDH CYP4Z2P ALMS1 FADS2 HDAC10

1.70e-035601168EFO_0004725
Diseasedecreased susceptibility to hepatitis C infection

PSTK PTPRD

1.77e-03161162EFO_0010101
Diseasephosphatidylcholine 38:6 measurement

CPOX FADS2

1.77e-03161162EFO_0010388
DiseaseN-acetylarginine measurement

SLC16A9 ALMS1

1.77e-03161162EFO_0021429
Diseaselysophosphatidylcholine measurement

WWOX FADS2 MGA

1.89e-03621163EFO_0010224
Diseasesevere acute respiratory syndrome, COVID-19

WWOX DGKB ABLIM1 PTPRD TRPM1 MYB TBL1X

1.98e-034471167EFO_0000694, MONDO_0100096
Diseaselysophosphatidylcholine 22:6 measurement

WWOX FADS2

2.25e-03181162EFO_0010365
Diseasereasoning

ZFP90 WWOX

2.51e-03191162EFO_0004350
Diseasered blood cell density measurement

HIVEP1 WWOX JMJD1C PHGDH FOCAD DST FAM13A FADS2 PRKCE MYB

2.51e-0388011610EFO_0007978
DiseaseProstate cancer, familial

TTC28 NBN MSMB

2.57e-03691163C2931456
DiseaseNon-alcoholic Fatty Liver Disease

PRKACA PRKCE ALDH1A1

2.68e-03701163C0400966
DiseaseNonalcoholic Steatohepatitis

PRKACA PRKCE ALDH1A1

2.68e-03701163C3241937
Diseasebasophil count, eosinophil count

JAK1 ANAPC1 FADS2 IL33 MYB

2.68e-032411165EFO_0004842, EFO_0005090
Diseasecholesteryl esters:total lipids ratio, high density lipoprotein cholesterol measurement

JMJD1C DNAH1 SLC12A3 FAM13A FADS2

2.78e-032431165EFO_0004612, EFO_0020944
Diseasephosphatidylcholine 34:2 measurement

CACNA1A FADS2

2.78e-03201162EFO_0010376
Diseasenasopharyngeal neoplasm

DGKB GRIK1 HMGXB3 C5

3.03e-031511164EFO_0004252
Diseasegestational age, birth measurement

PTPRD FADS2

3.06e-03211162EFO_0005112, EFO_0006921
Diseaselung cancer (is_implicated_in)

RAD52 MAP2K4 CYP24A1

3.13e-03741163DOID:1324 (is_implicated_in)
Diseaseplatelet-to-lymphocyte ratio

TTC28 STK38 JMJD1C PHGDH FADS2 MYB

3.18e-033631166EFO_0008446
Diseasenicotine dependence symptom count, depressive symptom measurement

VGLL3 SLC16A9 PHGDH

3.25e-03751163EFO_0007006, EFO_0009262
Diseaseallergic disease

SMURF1 KPNA7 CSF2RB ANAPC1 IL33

3.59e-032581165MONDO_0005271
Diseaseinsulin sensitivity measurement

PHGDH FADS2

3.67e-03231162EFO_0004471
Diseasesmall cell lung carcinoma

RAD52 PIWIL4 IL33

3.90e-03801163EFO_0000702

Protein segments in the cluster

PeptideGeneStartEntry
WPQVLKHSVDATFEN

CACNA1A

1461

O00555
QDPKSAVSHKILESW

CYP4Z2P

106

Q8N1L4
QQEILAAKPWTKDHH

COPS5

36

Q92905
AVKDTLWHSKQNPQI

ERBIN

986

Q96RT1
LSKDKQVEKWSQPVH

EPB42

196

P16452
EWKSSQRFSDTQPKH

C2orf80

176

Q0P641
VWHPDCKQSTKTEEK

ABLIM1

331

O14639
HPVTLGEQQWKSEKQ

ANKRD1

51

Q15327
IQTRWKHPSVDNKDL

GRIK1

131

P39086
NKKNSHEGVSWFVPV

ALMS1

3951

Q8TCU4
WDVSKGQKISIFNEH

CHAF1B

156

Q13112
NNEWHDSVSGKKFPV

ALDH1A1

26

P00352
QVKDHEDSSLQWSNP

CADM3

51

Q8N126
HQTNNKWNKRPDKSS

CASP8AP2

991

Q9UKL3
STASVPEQDTAKHWN

CCDC154

56

A6NI56
SFTIKVHDVNDNWPV

CDH5

136

P33151
WSRDLVNPKNKTHAC

NWD1

246

Q149M9
KLKISPEQHWDFTAE

MAP2K4

86

P45985
HTQSQAAWLCAKPFK

NXPH4

261

O95158
HQKPQAKSGSWDLQT

RAD52

376

P43351
KQSINSDWKIEHSGA

ADAMTS19

836

Q8TE59
DNEQSVWRHSPKKQK

JAK1

121

P23458
PADFHKENTVTNDWI

SERPIND1

56

P05546
SQIDSAWIVYNKPKH

ANAPC1

1151

Q9H1A4
VSVPTFSWEEIQKHN

FADS2

16

O95864
DWKQDSLLHKNPTVT

SLC16A9

246

Q7RTY1
SKSDKWIDIHNPATN

ALDH6A1

51

Q02252
HNKPSIQKEAAWALS

KPNA7

336

A9QM74
DFLKKWESPAQNTAH

PRKACA

26

P17612
ADELKSEVSWIPNKH

LARGE1

201

O95461
PEWNKVFTFNIKDIH

MCTP1

671

Q6DN14
KSTFTEPVLWRKDQH

NLRC4

131

Q9NPP4
PHFKNVKERTNWTNE

MBTPS1

226

Q14703
NKVDNPEADHLSSKW

MGA

431

Q8IWI9
TVQSPKHEWKIVASE

IVNS1ABP

281

Q9Y6Y0
HEINQQSPFWEISKA

KCNJ6

281

P48051
WLDTKKEEQNKSHPI

DST

4861

Q03001
TKQKTNSPAWHDEFV

PRKCE

56

Q02156
WQDEHKFRKPTALSA

MOB3A

101

Q96BX8
SKWVHPENAVNAEAS

JMJD1C

881

Q15652
GSLKWNNITEEAHKT

DDX60

231

Q8IY21
QDEHSAPFSWETKSQ

C1orf198

116

Q9H425
HLPQSEINKKISESW

HMGXB3

66

Q12766
VEQHKSSSWINKDGS

PEX3

216

P56589
WEKVEVSSNPHRASK

CUL7

841

Q14999
WNHEDVSAKNPSIKS

FRYL

1766

O94915
TPTEKKQWNHVCEQF

DNAJC28

286

Q9NX36
LSQAFNHWLKVPEDK

GGPS1

31

O95749
NHLNPEVKKTSWTEE

MYB

136

P10242
AQCRTDFTPHWKQEK

GATAD2B

421

Q8WXI9
LKGNKHPINSEWQTD

MSMB

41

P08118
HSDKAANPEVLKWTN

FAM13A

696

O94988
FTWEHSNLEVNKPKN

PTPRS

1406

Q13332
THQVACVENWPSKKD

NPY6R

191

Q99463
THFIDPQSQANKWIK

DNAH1

3231

Q9P2D7
ESIQSARAAQAPHWK

HDAC10

341

Q969S8
LSPTKDFWLHANNKE

IL33

186

O95760
ATWKDSKTETLQNAH

CSF2RB

381

P32927
KHENSVECWNPDTNT

KLHL28

351

Q9NXS3
ENKKPQDSVLWSHSR

C2orf83

131

Q53S99
PVELHKSLNTKVWQD

CYP24A1

256

Q07973
KRKQNPHSENEDSDW

QRSL1

151

Q9H0R6
RFWKDNLQHKDSSVP

C5

1226

P01031
KWAHLSPSEFSQLQK

DGKB

6

Q9Y6T7
KSPSHVWIFAQSVKD

FRY

836

Q5TBA9
KHCDDSFTPQEKLWQ

CPOX

371

P36551
DTTAQLSWKEGKDNH

CNTN3

611

Q9P232
NHLNPEVKKSSWTEE

MYBL1

131

P10243
WTHTQNKDPIVANAA

FOCAD

696

Q5VW36
KQRTDPHWSAVQKAI

NPHP1

241

O15259
TWEHSNLEVNKPKNR

PTPRD

1371

P23468
SNHPETDYKNKDWVF

STK38

426

Q15208
IVKSDSQHRFWKPSE

UVSSA

521

Q2YD98
QESVFQSPESWKEHK

PRUNE2

676

Q8WUY3
LDHTWTNSKPPKEDQ

PRUNE2

886

Q8WUY3
DPKENSKTWKNDSTH

TRHR

226

P34981
KSVLDQWSSHKVAFD

SYNE1

7126

Q8NF91
ATPSLWKNKEQHLSE

NBN

496

O60934
SKFEPVLQWTKHCDN

RFX1

671

P22670
IDWSVKPTHTFQKRD

PIWIL4

316

Q7Z3Z4
EQDKVPHTAQRAAWK

ST6GALNAC1

111

Q9NSC7
VPETWAKFSNDNIKH

TEKT5

291

Q96M29
TLKHPQTAKWDNFLA

SCFD2

416

Q8WU76
PQTWEDPHEKDKSTN

PPA2

146

Q9H2U2
KPKAEGQASENKWSH

SWT1

161

Q5T5J6
TDTVKNTLDPKWNQH

SMURF1

51

Q9HCE7
FVTSKLWNTKHHPED

AKR1A1

76

P14550
DKSPESHKAKNESWI

C10orf62

21

Q5T681
QDPKSAVSHKILESW

CYP4Z1

106

Q86W10
LKDNSQKHIEVWDPS

RNF17

871

Q9BXT8
DTVKNTLDPKWNQHY

SMURF2

51

Q9HAU4
QAHNKEIYTIKWSPT

TBL1X

451

O60907
NPEKHISHKAALEWT

TIGD2

471

Q4W5G0
WKPGTQANISQSHKD

VSTM5

81

A8MXK1
ESTLDHWKFPQEQNK

USP17L4

431

A6NCW7
AVFAKKPDSWHVKDN

SLFN12L

331

Q6IEE8
KESWKNNPAIKHVFS

TTI2

216

Q6NXR4
PKSVAVNAEEKWVHF

SGIP1

301

Q9BQI5
KPNPEKNAWEHNSLT

PSTK

211

Q8IV42
NHTEEKTQWEHPKTG

WWOX

36

Q9NZC7
GFKKNWQSAHPATVE

SLC12A3

741

P55017
EWGNPSSDEKHKNYI

PREPL

606

Q4J6C6
TDKWAFTPLHEAAQK

TNKS2

741

Q9H2K2
DKVYTHPKWNTQTKA

ZC2HC1C

66

Q53FD0
ETQPEKWSVAKHTQS

TRPM1

36

Q7Z4N2
KVVQSSKAFSHPSNW

TTC28

1691

Q96AY4
GSSSKWEEVQSKANH

SLC30A4

381

O14863
TPKHSVAFSKWQEQA

TPRN

661

Q4KMQ1
VSDTNSKSWANHENK

UEVLD

166

Q8IX04
VSQPKSWASLFHDSK

USP10

336

Q14694
ESTLDHWKFPQEQNK

USP17L7

431

P0C7H9
ESTLDHWKFPQEQNK

USP17L8

431

P0C7I0
PSLEAWKQHVTEAFQ

PHGDH

516

O43175
DWPQTFEKFHVQKEI

TRAPPC9

91

Q96Q05
DTGLQHQDKSKESPW

VGLL3

311

A8MV65
NPLQKWEDSAHKPQS

TNFRSF1A

336

P19438
CHDQEKSEKFSWPQR

HIVEP1

1251

P15822
TEKAEHSELKSPWQA

SNAPC2

296

Q13487
ESTLDHWKFPQEQNK

USP17L2

431

Q6R6M4
DWKTRPEVKSSHLQQ

ZFP90

86

Q8TF47