Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionDNA-binding transcription factor activity, RNA polymerase II-specific

ZNF620 ZNF717 PLAGL1 ZNF397 ZNF101 ZNF25 TSHZ2 ZNF665 ZNF540 ZFP62 ZNF260 ZNF331 ZNF189

5.19e-0714123613GO:0000981
GeneOntologyMolecularFunctionRNA polymerase II transcription regulatory region sequence-specific DNA binding

ZNF620 ZNF717 PLAGL1 ZNF397 ZNF101 ZNF763 ZNF25 ZNF665 ZNF540 ZFP62 ZNF260 ZNF331 ZNF189

7.54e-0714593613GO:0000977
GeneOntologyMolecularFunctionRNA polymerase II cis-regulatory region sequence-specific DNA binding

ZNF717 PLAGL1 ZNF397 ZNF101 ZNF763 ZNF665 ZNF540 ZFP62 ZNF260 ZNF331 ZNF189

7.42e-0612443611GO:0000978
GeneOntologyMolecularFunctioncis-regulatory region sequence-specific DNA binding

ZNF717 PLAGL1 ZNF397 ZNF101 ZNF763 ZNF665 ZNF540 ZFP62 ZNF260 ZNF331 ZNF189

9.10e-0612713611GO:0000987
GeneOntologyMolecularFunctionhistone H3 methyltransferase activity

SETDB1 SMYD2

2.85e-0344362GO:0140938
GeneOntologyMolecularFunctionextracellular matrix structural constituent

LAMA2 LAMA3 MUC2

4.67e-03188363GO:0005201
GeneOntologyMolecularFunctionserine-type endopeptidase activity

PCSK5 ST14 PCSK6

4.81e-03190363GO:0004252
GeneOntologyMolecularFunctionpeptidase activity

PCSK5 USP18 ADAM28 ST14 PCSK6

6.04e-03654365GO:0008233
GeneOntologyMolecularFunctionserine-type peptidase activity

PCSK5 ST14 PCSK6

6.09e-03207363GO:0008236
GeneOntologyMolecularFunctionserine hydrolase activity

PCSK5 ST14 PCSK6

6.51e-03212363GO:0017171
GeneOntologyMolecularFunctionprotein-lysine N-methyltransferase activity

SETDB1 SMYD2

6.68e-0368362GO:0016279
GeneOntologyMolecularFunctionlysine N-methyltransferase activity

SETDB1 SMYD2

6.87e-0369362GO:0016278
GeneOntologyMolecularFunctionendopeptidase activity

PCSK5 ADAM28 ST14 PCSK6

7.25e-03430364GO:0004175
GeneOntologyMolecularFunctionhistone methyltransferase activity

SETDB1 SMYD2

7.26e-0371362GO:0042054
GeneOntologyMolecularFunctionp53 binding

BLM SMYD2

8.49e-0377362GO:0002039
GeneOntologyMolecularFunctiondamaged DNA binding

BLM ZNF101

1.00e-0284362GO:0003684
GeneOntologyCellularComponentGolgi lumen

PCSK5 MUC2 PCSK6

8.69e-04109363GO:0005796
DomainZINC_FINGER_C2H2_2

ZNF620 PLAGL1 ZNF397 ZNF101 ZNF763 ZNF25 TSHZ2 ZNF665 ZNF540 ZFP62 ZNF260 ZNF804B ZNF331 ZNF189

4.12e-117753514PS50157
DomainZINC_FINGER_C2H2_1

ZNF620 PLAGL1 ZNF397 ZNF101 ZNF763 ZNF25 TSHZ2 ZNF665 ZNF540 ZFP62 ZNF260 ZNF804B ZNF331 ZNF189

4.26e-117773514PS00028
DomainZnf_C2H2-like

ZNF620 PLAGL1 ZNF397 ZNF101 ZNF763 ZNF25 TSHZ2 ZNF665 ZNF540 ZFP62 ZNF260 ZNF804B ZNF331 ZNF189

5.87e-117963514IPR015880
DomainZnf_C2H2

ZNF620 PLAGL1 ZNF397 ZNF101 ZNF763 ZNF25 TSHZ2 ZNF665 ZNF540 ZFP62 ZNF260 ZNF804B ZNF331 ZNF189

6.82e-118053514IPR007087
DomainZnF_C2H2

ZNF620 PLAGL1 ZNF397 ZNF101 ZNF763 ZNF25 TSHZ2 ZNF665 ZNF540 ZFP62 ZNF260 ZNF804B ZNF331 ZNF189

7.16e-118083514SM00355
Domainzf-C2H2

ZNF620 PLAGL1 ZNF397 ZNF101 ZNF763 ZNF25 TSHZ2 ZNF665 ZNF540 ZFP62 ZNF260 ZNF331 ZNF189

1.57e-106933513PF00096
Domain-

ZNF620 PLAGL1 ZNF397 ZNF101 ZNF763 ZNF25 ZNF665 ZNF540 ZFP62 ZNF260 ZNF331 ZNF189

1.87e-0967935123.30.160.60
DomainZnf_C2H2/integrase_DNA-bd

ZNF620 PLAGL1 ZNF397 ZNF101 ZNF763 ZNF25 ZNF665 ZNF540 ZFP62 ZNF260 ZNF331 ZNF189

2.40e-096943512IPR013087
DomainEGF

LAMA2 PCSK5 LAMA3 RSPO3 SCUBE2 CELSR2 ADAM28 PCSK6

9.79e-09235358SM00181
DomainEGF-like_dom

LAMA2 PCSK5 LAMA3 SCUBE2 CELSR2 ADAM28 PCSK6

3.37e-07249357IPR000742
DomainGrowth_fac_rcpt_

PCSK5 LAMA3 RSPO3 SCUBE2 CELSR2 PCSK6

4.10e-07156356IPR009030
Domainzf-C2H2_6

ZNF620 ZNF763 ZNF25 ZNF540 ZFP62 ZNF260 ZNF331

1.59e-06314357PF13912
DomainKRAB

ZNF620 ZNF101 ZNF763 ZNF25 ZNF540 ZNF331 ZNF189

3.80e-06358357PS50805
DomainKRAB

ZNF620 ZNF101 ZNF763 ZNF25 ZNF540 ZNF331 ZNF189

3.80e-06358357PF01352
DomainKRAB

ZNF620 ZNF101 ZNF763 ZNF25 ZNF540 ZNF331 ZNF189

4.63e-06369357SM00349
DomainKRAB

ZNF620 ZNF101 ZNF763 ZNF25 ZNF540 ZNF331 ZNF189

4.72e-06370357IPR001909
DomainFurin_repeat

PCSK5 RSPO3 PCSK6

4.83e-0618353IPR006212
DomainFU

PCSK5 RSPO3 PCSK6

4.83e-0618353SM00261
DomainEGF_LAM_2

LAMA2 LAMA3 CELSR2

2.36e-0530353PS50027
DomainEGF_LAM_1

LAMA2 LAMA3 CELSR2

2.36e-0530353PS01248
DomainLaminin_aI

LAMA2 LAMA3

3.40e-055352IPR009254
DomainLaminin_I

LAMA2 LAMA3

3.40e-055352PF06008
DomainLaminin_II

LAMA2 LAMA3

3.40e-055352PF06009
DomainLaminin_domII

LAMA2 LAMA3

3.40e-055352IPR010307
DomainLaminin_EGF

LAMA2 LAMA3 CELSR2

3.79e-0535353PF00053
DomainEGF_Lam

LAMA2 LAMA3 CELSR2

3.79e-0535353SM00180
DomainLAM_G_DOMAIN

LAMA2 LAMA3 CELSR2

4.86e-0538353PS50025
DomainLaminin_EGF

LAMA2 LAMA3 CELSR2

4.86e-0538353IPR002049
DomainGF_recep_IV

PCSK5 PCSK6

5.09e-056352PF14843
DomainGF_recep_IV

PCSK5 PCSK6

5.09e-056352IPR032778
DomainPeptidase_S8_Asp-AS

PCSK5 PCSK6

5.09e-056352IPR023827
DomainLaminin_G_2

LAMA2 LAMA3 CELSR2

5.68e-0540353PF02210
DomainPrprotnconvertsP

PCSK5 PCSK6

7.12e-057352IPR002884
DomainP_proprotein

PCSK5 PCSK6

7.12e-057352PF01483
DomainS8_pro-domain

PCSK5 PCSK6

7.12e-057352IPR032815
Domain-

PCSK5 PCSK6

7.12e-0573523.30.70.850
DomainS8_pro-domain

PCSK5 PCSK6

7.12e-057352PF16470
DomainLamG

LAMA2 LAMA3 CELSR2

7.57e-0544353SM00282
DomainLAMININ_IVA

LAMA2 LAMA3

9.49e-058352PS51115
DomainLaminin_B

LAMA2 LAMA3

9.49e-058352PF00052
DomainLamB

LAMA2 LAMA3

9.49e-058352SM00281
DomainLaminin_IV

LAMA2 LAMA3

9.49e-058352IPR000034
DomainEGF_1

LAMA2 LAMA3 SCUBE2 CELSR2 ADAM28

1.06e-04255355PS00022
DomainEGF-like_CS

LAMA2 LAMA3 SCUBE2 CELSR2 ADAM28

1.18e-04261355IPR013032
DomainPeptidase_S8_His-AS

PCSK5 PCSK6

1.22e-049352IPR022398
DomainPeptidase_S8_Ser-AS

PCSK5 PCSK6

1.22e-049352IPR023828
DomainEGF_2

LAMA2 LAMA3 SCUBE2 CELSR2 ADAM28

1.27e-04265355PS01186
DomainPeptidase_S8_subtilisin-rel

PCSK5 PCSK6

1.52e-0410352IPR015500
DomainSUBTILASE_ASP

PCSK5 PCSK6

1.52e-0410352PS00136
DomainSUBTILASE_HIS

PCSK5 PCSK6

1.52e-0410352PS00137
DomainSUBTILASE_SER

PCSK5 PCSK6

1.52e-0410352PS00138
DomainLaminin_G

LAMA2 LAMA3 CELSR2

1.73e-0458353IPR001791
DomainPeptidase_S8

PCSK5 PCSK6

1.86e-0411352PF00082
Domain-

PCSK5 PCSK6

1.86e-04113523.40.50.200
DomainPeptidase_S8/S53_dom

PCSK5 PCSK6

1.86e-0411352IPR000209
DomainPLAC

PCSK5 PCSK6

3.06e-0414352PF08686
Domain-

LAMA2 PCSK5 PCSK6

3.43e-04733532.60.120.260
DomainLAMININ_NTER

LAMA2 LAMA3

4.03e-0416352PS51117
DomainLaminin_N

LAMA2 LAMA3

4.03e-0416352PF00055
DomainLaminin_N

LAMA2 LAMA3

4.03e-0416352IPR008211
DomainLamNT

LAMA2 LAMA3

4.03e-0416352SM00136
DomainPropept_inh

PCSK5 PCSK6

4.56e-0417352IPR009020
DomainPLAC

PCSK5 PCSK6

5.72e-0419352IPR010909
DomainPLAC

PCSK5 PCSK6

5.72e-0419352PS50900
DomainGalactose-bd-like

LAMA2 PCSK5 PCSK6

7.19e-0494353IPR008979
Domain-

LAMA2 LAMA3 CELSR2

7.42e-04953532.60.120.200
DomainEphrin_rec_like

PCSK5 SCUBE2

9.96e-0425352SM01411
DomainTyr-kin_ephrin_A/B_rcpt-like

PCSK5 SCUBE2

9.96e-0425352IPR011641
DomainSET

SETDB1 SMYD2

2.67e-0341352PF00856
DomainSET

SETDB1 SMYD2

3.35e-0346352SM00317
DomainCUB

SCUBE2 ST14

3.80e-0349352PF00431
DomainSET_dom

SETDB1 SMYD2

3.95e-0350352IPR001214
DomainCUB

SCUBE2 ST14

3.95e-0350352SM00042
DomainSET

SETDB1 SMYD2

3.95e-0350352PS50280
Domain-

SCUBE2 ST14

4.27e-03523522.60.120.290
DomainCUB

SCUBE2 ST14

4.43e-0353352PS01180
DomainCUB_dom

SCUBE2 ST14

5.10e-0357352IPR000859
PathwayREACTOME_RNA_POLYMERASE_II_TRANSCRIPTION

BLM ZNF620 ZNF717 RSPO3 PLAGL1 ZNF101 ZNF25 ZNF665 ZNF540 SMYD2 ZNF804B ZNF331 ZNF189

6.97e-0713872813M734
PathwayREACTOME_REGULATION_OF_ENDOGENOUS_RETROELEMENTS

SETDB1 ZNF101 ZNF665

1.81e-0456283MM17236
PathwayREACTOME_ASSEMBLY_OF_ACTIVE_LPL_AND_LIPC_LIPASE_COMPLEXES

PCSK5 PCSK6

2.07e-0411282MM15559
PathwayPID_INTEGRIN4_PATHWAY

LAMA2 LAMA3

2.07e-0411282M158
PathwayREACTOME_GENERIC_TRANSCRIPTION_PATHWAY

BLM ZNF101 ZNF25 ZNF665 SMYD2 ZNF804B ZNF189

5.99e-04768287MM14851
PathwayREACTOME_GENE_EXPRESSION_TRANSCRIPTION

BLM SETDB1 ZNF101 ZNF25 ZNF665 SMYD2 ZNF804B ZNF189

6.23e-041022288MM15436
PathwayREACTOME_ASSEMBLY_OF_ACTIVE_LPL_AND_LIPC_LIPASE_COMPLEXES

PCSK5 PCSK6

6.37e-0419282M27839
PathwayREACTOME_PLASMA_LIPOPROTEIN_REMODELING

PCSK5 PCSK6

1.11e-0325282MM15562
PathwayREACTOME_MET_ACTIVATES_PTK2_SIGNALING

LAMA2 LAMA3

1.60e-0330282M27772
PathwayREACTOME_LAMININ_INTERACTIONS

LAMA2 LAMA3

1.60e-0330282M27216
PathwayBIOCARTA_AGR_PATHWAY

LAMA2 LAMA3

1.71e-0331282MM1343
PathwayWP_ALPHA_6_BETA_4_SIGNALING

LAMA2 LAMA3

1.93e-0333282M39503
PathwayBIOCARTA_AGR_PATHWAY

LAMA2 LAMA3

1.93e-0333282M6220
PathwayREACTOME_PLASMA_LIPOPROTEIN_REMODELING

PCSK5 PCSK6

2.05e-0334282M27842
PathwayREACTOME_EPIGENETIC_REGULATION_OF_GENE_EXPRESSION

SETDB1 ZNF101 ZNF665

2.41e-03136283MM14848
PathwayREACTOME_MET_PROMOTES_CELL_MOTILITY

LAMA2 LAMA3

2.97e-0341282M27778
PathwayREACTOME_PKMTS_METHYLATE_HISTONE_LYSINES

SETDB1 SMYD2

3.73e-0346282MM14933
PathwayPID_A6B1_A6B4_INTEGRIN_PATHWAY

LAMA2 LAMA3

3.73e-0346282M239
Pubmed

Rapid and efficient cloning of cDNAs encoding Krüppel-like zinc finger proteins by degenerate PCR.

ZNF101 ZNF25 ZNF665 ZFP62

1.98e-07493649630514
Pubmed

Identification of an isoform with an extremely large Cys-rich region of PC6, a Kex2-like processing endoprotease.

PCSK5 PCSK6

1.04e-0623628335106
Pubmed

Macromolecular organization of basement membranes.

LAMA2 LAMA3

1.04e-0623628939648
Pubmed

Identification and functional expression of a new member of the mammalian Kex2-like processing endoprotease family: its striking structural similarity to PACE4.

PCSK5 PCSK6

1.04e-0623628468318
Pubmed

Cell-surface processing of extracellular human immunodeficiency virus type 1 Vpr by proprotein convertases.

PCSK5 PCSK6

1.04e-06236218061232
Pubmed

Maturation of HIV envelope glycoprotein precursors by cellular endoproteases.

PCSK5 PCSK6

3.12e-06336211063880
Pubmed

USP18 promotes innate immune responses and apoptosis in influenza A virus-infected A549 cells via cGAS-STING pathway.

USP18 CGAS

3.12e-06336237422930
Pubmed

Comparative cellular processing of the human immunodeficiency virus (HIV-1) envelope glycoprotein gp160 by the mammalian subtilisin/kexin-like convertases.

PCSK5 PCSK6

3.12e-0633628670066
Pubmed

CDMP1/GDF5 has specific processing requirements that restrict its action to joint surfaces.

PCSK5 PCSK6

6.24e-06436216829522
Pubmed

Cellular processing of the nerve growth factor precursor by the mammalian pro-protein convertases.

PCSK5 PCSK6

6.24e-0643628615794
Pubmed

The proprotein convertases furin and PACE4 play a significant role in tumor progression.

PCSK5 PCSK6

6.24e-06436210900462
Pubmed

Neurotrophin secretion: current facts and future prospects.

PCSK5 PCSK6

6.24e-06436212787574
Pubmed

Retroviral envelope glycoprotein processing: structural investigation of the cleavage site.

PCSK5 PCSK6

6.24e-0643629521771
Pubmed

Expression and distribution of laminin alpha1 and alpha2 chains in embryonic and adult mouse tissues: an immunochemical approach.

LAMA2 LAMA3

1.04e-05536211969289
Pubmed

Processing of prothyrotropin-releasing hormone by the family of prohormone convertases.

PCSK5 PCSK6

1.04e-0553629242664
Pubmed

Complete sequence, recombinant analysis and binding to laminins and sulphated ligands of the N-terminal domains of laminin alpha3B and alpha5 chains.

LAMA2 LAMA3

1.04e-05536211829758
Pubmed

Proprotein convertase expression and localization in epidermis: evidence for multiple roles and substrates.

PCSK5 PCSK6

1.04e-05536211380615
Pubmed

Regulation of prohepcidin processing and activity by the subtilisin-like proprotein convertases Furin, PC5, PACE4 and PC7.

PCSK5 PCSK6

1.04e-05536218664504
Pubmed

Differential expression of five laminin alpha (1-5) chains in developing and adult mouse kidney.

LAMA2 LAMA3

1.04e-0553629415429
Pubmed

Differential expression of laminin alpha chains during murine tooth development.

LAMA2 LAMA3

1.04e-0553629389447
Pubmed

Murine subtilisin-like proteinase SPC6 is expressed during embryonic implantation, somitogenesis, and skeletal formation.

PCSK5 PCSK6

1.56e-0563629291583
Pubmed

HIV-protein-mediated alterations in T cell interactions with the extracellular matrix proteins and endothelium.

LAMA2 LAMA3

1.56e-0563629597096
Pubmed

The cysteine-rich domain of the secreted proprotein convertases PC5A and PACE4 functions as a cell surface anchor and interacts with tissue inhibitors of metalloproteinases.

PCSK5 PCSK6

1.56e-05636216135528
Pubmed

Identification of the paired basic convertases implicated in HIV gp160 processing based on in vitro assays and expression in CD4(+) cell lines.

PCSK5 PCSK6

1.56e-0563628940009
Pubmed

Laminins promote the locomotion of skeletal myoblasts via the alpha 7 integrin receptor.

LAMA2 LAMA3

2.18e-0573629004048
Pubmed

Proteolytic processing in the secretory pathway.

PCSK5 PCSK6

2.18e-05736210409610
Pubmed

The family of subtilisin/kexin like pro-protein and pro-hormone convertases: divergent or shared functions.

PCSK5 PCSK6

2.18e-0573627819324
Pubmed

Roles for laminin in embryogenesis: exencephaly, syndactyly, and placentopathy in mice lacking the laminin alpha5 chain.

LAMA2 LAMA3

2.91e-0583629852162
Pubmed

Chromosomal assignment of the genes for proprotein convertases PC4, PC5, and PACE 4 in mouse and human.

PCSK5 PCSK6

2.91e-0583627782070
Pubmed

Cloning and expression analyses of mouse dystroglycan gene: specific expression in maternal decidua at the peri-implantation stage.

LAMA2 LAMA3

2.91e-0583628872465
Pubmed

Zac1 (Lot1), a potential tumor suppressor gene, and the gene for epsilon-sarcoglycan are maternally imprinted genes: identification by a subtractive screen of novel uniparental fibroblast lines.

LAMA2 PLAGL1

2.91e-05836210757814
Pubmed

Regulation of bone morphogenetic protein activity by pro domains and proprotein convertases.

PCSK5 PCSK6

2.91e-0583629885250
Pubmed

Cellular localization and role of prohormone convertases in the processing of pro-melanin concentrating hormone in mammals.

PCSK5 PCSK6

2.91e-05836210037747
Pubmed

The multifaceted proprotein convertases: their unique, redundant, complementary, and opposite functions.

PCSK5 PCSK6

3.73e-05936223775089
Pubmed

The activation and physiological functions of the proprotein convertases.

PCSK5 PCSK6

3.73e-05936218343183
Pubmed

SPC4, SPC6, and the novel protease SPC7 are coexpressed with bone morphogenetic proteins at distinct sites during embryogenesis.

PCSK5 PCSK6

3.73e-0593628698813
Pubmed

The prohormone theory and the proprotein convertases: it is all about serendipity.

PCSK5 PCSK6

3.73e-05936221805236
Pubmed

The proprotein convertases, 20 years later.

PCSK5 PCSK6

3.73e-05936221805237
Pubmed

The biology and therapeutic targeting of the proprotein convertases.

PCSK5 PCSK6

3.73e-05936222679642
Pubmed

Expression and transient nuclear translocation of proprotein convertase 1 (PC1) during mouse preimplantation embryonic development.

PCSK5 PCSK6

4.66e-051036216163737
Pubmed

Distribution of the ten known laminin chains in the pathways and targets of developing sensory axons.

LAMA2 LAMA3

4.66e-05103629034910
Pubmed

Laminin alpha 5 is required for lobar septation and visceral pleural basement membrane formation in the developing mouse lung.

LAMA2 LAMA3

5.70e-051136212051813
Pubmed

Regional differences in the expression of laminin isoforms during mouse neural tube development.

LAMA2 LAMA3

5.70e-051136221524702
Pubmed

Molecular dissection of laminin alpha 5 in vivo reveals separable domain-specific roles in embryonic development and kidney function.

LAMA2 LAMA3

6.83e-051236216750824
Pubmed

Distribution and function of laminins in the neuromuscular system of developing, adult, and mutant mice.

LAMA2 LAMA3

6.83e-05123629396756
Pubmed

Fukutin-related protein alters the deposition of laminin in the eye and brain.

LAMA2 LAMA3

8.07e-051336221900571
Pubmed

The laminin alpha chains: expression, developmental transitions, and chromosomal locations of alpha1-5, identification of heterotrimeric laminins 8-11, and cloning of a novel alpha3 isoform.

LAMA2 LAMA3

9.41e-05143629151674
Pubmed

Genome-wide association study identifies multiple susceptibility loci for pulmonary fibrosis.

IVD MUC2

1.08e-041536223583980
Pubmed

Localization of basement membrane-associated protein isoforms during development of the ocular surface of mouse eye.

LAMA2 LAMA3

1.08e-04153629264260
Pubmed

Basement membrane composition in the early mouse embryo day 7.

LAMA2 LAMA3

1.08e-041536215895400
Pubmed

Imaging proprotein convertase activities and their regulation in the implanting mouse blastocyst.

PCSK5 PCSK6

1.24e-041636220876279
Pubmed

Laminin alpha5 is necessary for submandibular gland epithelial morphogenesis and influences FGFR expression through beta1 integrin signaling.

LAMA2 LAMA3

1.24e-041636217601529
Pubmed

Amplification of extracellular matrix and oncogenes in tat-transfected human salivary gland cell lines with expression of laminin, fibronectin, collagens I, III, IV, c-myc and p53.

LAMA2 LAMA3

1.58e-041836211311202
Pubmed

Furin is the primary in vivo convertase of angiopoietin-like 3 and endothelial lipase in hepatocytes.

PCSK5 PCSK6

1.96e-042036223918928
Pubmed

Laminin and integrin expression in the ventral ectodermal ridge of the mouse embryo: implications for regulation of BMP signalling.

LAMA2 LAMA3

1.96e-042036222911573
Pubmed

Age of onset of amyotrophic lateral sclerosis is modulated by a locus on 1p34.1.

PCSK5 LAMA3

2.16e-042136222959728
Pubmed

Chromosomal localization of the genes for five zinc finger proteins expressed in mouse lens.

ZFP62 ZNF260

2.38e-04223627590745
Pubmed

Zfp296 negatively regulates H3K9 methylation in embryonic development as a component of heterochromatin.

SETDB1 PLAGL1

2.38e-042236228963472
Pubmed

Clustering of C2-H2 zinc finger motif sequences within telomeric and fragile site regions of human chromosomes.

ZNF397 ZNF763

2.38e-04223621505991
Pubmed

Mutations of the Transcriptional Corepressor ZMYM2 Cause Syndromic Urinary Tract Malformations.

BLM SETDB1 ZNF397

2.97e-0412536332891193
Pubmed

Cannabinoid inhibits HIV-1 Tat-stimulated adhesion of human monocyte-like cells to extracellular matrix proteins.

LAMA2 LAMA3

3.33e-042636224742657
Pubmed

Basement membrane assembly of the integrin α8β1 ligand nephronectin requires Fraser syndrome-associated proteins.

LAMA2 LAMA3

4.16e-042936222613833
Pubmed

Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.

ZNF101 CELSR2

5.72e-043436219060911
Pubmed

The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.

LAMA2 LAMA3 MUC2

6.91e-0416736322159717
Pubmed

Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits.

RSPO3 CELSR2

7.54e-043936221909109
Pubmed

Thyroid follicle development requires Smad1/5- and endothelial cell-dependent basement membrane assembly.

LAMA2 LAMA3

7.93e-044036227068110
Pubmed

Acetylation-Mimic Mutation of TRIM28-Lys304 to Gln Attenuates the Interaction with KRAB-Zinc-Finger Proteins and Affects Gene Expression in Leukemic K562 Cells.

ZNF620 ZNF101 ZNF25

8.72e-0418136337372979
Cytoband19q13.12

ZNF540 ZNF260

1.48e-037236219q13.12
Cytoband19q13.42

ZNF665 ZNF331

4.36e-0312536219q13.42
CytobandEnsembl 112 genes in cytogenetic band chr6q22

LAMA2 RSPO3

4.50e-03127362chr6q22
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF620 ZNF717 PLAGL1 ZNF397 ZNF101 ZNF763 ZNF25 TSHZ2 ZNF665 ZNF540 ZFP62 ZNF260 ZNF331 ZNF189

1.73e-12718301428
GeneFamilyProprotein convertase subtilisin/kexin family

PCSK5 PCSK6

9.51e-059302973
GeneFamilyLaminin subunits

LAMA2 LAMA3

1.74e-0412302626
GeneFamilyZinc fingers C2H2-type|Lysine methyltransferases|PR/SET domain family

SETDB1 SMYD2

1.44e-0334302487
CoexpressionNABA_MATRISOME

LAMA2 PCSK5 LAMA3 RSPO3 SCUBE2 MUC2 ADAM28 ST14 PCSK6

6.55e-061008369MM17056
CoexpressionNABA_MATRISOME

LAMA2 PCSK5 LAMA3 RSPO3 SCUBE2 MUC2 ADAM28 ST14 PCSK6

7.55e-061026369M5889
ToppCell5'-GW_trimst-2-LymphNode-Mesenchymal-fibroblastic|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LAMA3 RSPO3 USP18 TSHZ2 ZNF804B

4.67e-07193365c5bd0ed6f57459e54d2463318e8d9b1879718e63
ToppCellCOPD-Stromal-Fibroblast|Stromal / Disease state, Lineage and Cell class

LAMA2 PCSK5 RSPO3 TSHZ2 PCSK6

5.04e-071963654930eeb303d174c28fd91021723e26fdf1af9170
ToppCellBronchial-10x5prime-Stromal-Fibroblastic-Fibro_immune_recruiting|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

LAMA2 LAMA3 RSPO3 SCUBE2 ZNF804B

5.43e-071993650cdbedf09ec72734b86ddab3fec562e066afed92
ToppCellP07-Endothelial-lymphatic_endothelial_cell|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

RSPO3 TSHZ2 PCSK6 SMYD2

8.93e-061633645cbab3d03bb1af9391ecad635d6eea1dd42c1337
ToppCellP07-Endothelial-lymphatic_endothelial_cell-endothelial_cell_of_lymphatic_vessel|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

RSPO3 TSHZ2 PCSK6 SMYD2

8.93e-06163364322ba94c3ec1e1859c2e2195ecb3f7dab8d190f6
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

LAMA2 RSPO3 TSHZ2 ZNF665

1.08e-05171364972fab891135bd755d5526cbc5a963200067b0a6
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

LAMA2 RSPO3 TSHZ2 ZNF665

1.08e-051713642a77ed79c6f2e700e789c80451a70ecb31639719
ToppCellP28-Endothelial-lymphatic_endothelial_cell-endothelial_cell_of_lymphatic_vessel|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

RSPO3 TSHZ2 PCSK6 SMYD2

1.24e-05177364e96a7e4544710aaab8bd2800ecff9667880a8bf4
ToppCellP28-Endothelial-lymphatic_endothelial_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

RSPO3 TSHZ2 PCSK6 SMYD2

1.24e-051773646e330aa3c87fd640526b746a9deb3b2250d2518c
ToppCelldroplet-Lung-nan-21m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RSPO3 TSHZ2 PCSK6 SMYD2

1.47e-051853643a4ae836e882e8d29eb0a2dfab5677f10f2d365f
ToppCelldroplet-Lung-nan-21m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RSPO3 TSHZ2 PCSK6 SMYD2

1.47e-05185364224f0b022c21dd40bf1f7503f00b3107ef958975
ToppCellLA-01._Fibroblast_I|World / Chamber and Cluster_Paper

LAMA2 PCSK5 TSHZ2 PCSK6

1.53e-051873644ea486991f66c29728d127171a07b81404ec0b78
ToppCelldroplet-Lung-21m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RSPO3 TSHZ2 PCSK6 SMYD2

1.63e-05190364a22a510b4a257eb0eaf09c7ae7978d3d2f07a58c
ToppCelldroplet-Lung-21m-Endothelial-lymphatic_endothelial|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RSPO3 TSHZ2 PCSK6 SMYD2

1.63e-0519036457c136bf6d7feafb4a220877bed0cc8fdf314db2
ToppCelldroplet-Lung-21m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RSPO3 TSHZ2 PCSK6 SMYD2

1.63e-05190364f50b9814a1beac67dc042a8c27dfd085ceeda3a6
ToppCellLA-14._Fibroblast_III|LA / Chamber and Cluster_Paper

LAMA2 PCSK5 TSHZ2 PCSK6

1.74e-051933647426c291bac59e539c427bcaae18abc7d397d44e
ToppCelldroplet-Fat-Mat-18m-Mesenchymal|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA2 PCSK5 RSPO3 TSHZ2

1.74e-05193364ebd090d7801480b3cee45caac3d30cc991836769
ToppCelldroplet-Fat-Mat-18m-Mesenchymal-Cd34+|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA2 PCSK5 RSPO3 TSHZ2

1.74e-0519336422c58032e58730715224d7934968ce92d150b0e8
ToppCelldroplet-Fat-Mat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA2 PCSK5 RSPO3 TSHZ2

1.74e-05193364573ad2f848bede1fe20c7b4b352a9242ec294725
ToppCelldroplet-Fat-BAT+GAT+MAT-30m-Mesenchymal|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA2 PCSK5 RSPO3 TSHZ2

1.77e-0519436454a7f693966b5c02f6b248950ddb5fa32af3ae67
ToppCelldroplet-Fat-BAT+GAT+MAT-30m-Mesenchymal-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA2 PCSK5 RSPO3 TSHZ2

1.77e-05194364da926441053b499cb5107ccb116fb1b3844d82b7
ToppCelldroplet-Fat-BAT+GAT+MAT-30m-Mesenchymal-mesenchymal_stem_cell_of_adipose|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA2 PCSK5 RSPO3 TSHZ2

1.77e-05194364f34b3bbdebf56f66ff499e390e5515a4a4093f90
ToppCellLA-02._Fibroblast_II|LA / Chamber and Cluster_Paper

LAMA2 PCSK5 TSHZ2 PCSK6

1.77e-05194364234d1494c114cce77c619708bbcd8d5ce805f19b
ToppCell5'-GW_trimst-2-LymphNode-Mesenchymal-fibroblastic-mLTo|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LAMA3 RSPO3 USP18 ZNF804B

1.77e-05194364c45e9d09b5cd6973de6c3f1713b3bf36fa4bfe57
ToppCellLA-02._Fibroblast_II|World / Chamber and Cluster_Paper

LAMA2 PCSK5 TSHZ2 PCSK6

1.81e-05195364a78b605b49acd8c9d68716266ca269dafcd910b9
ToppCell5'-GW_trimst-2-LymphNode-Mesenchymal|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LAMA3 RSPO3 USP18 TSHZ2

1.88e-051973645fbbc570a4e77c703f569a4f85ce2d8af67d6297
ToppCell(2)_Fibroblasts-(22)_Fibro-3|(2)_Fibroblasts / Cell class and subclass of bone marrow stroma cells in homeostatis

LAMA2 PCSK5 SCUBE2 TSHZ2

1.88e-05197364d9021bab82403e566ec10f78acb227c0f80b88fe
ToppCellControl-Stromal-Fibroblast|Stromal / Disease state, Lineage and Cell class

LAMA2 PCSK5 RSPO3 TSHZ2

1.88e-0519736464cc5f61c88e9560b0f8f6f3151255dffb5c3d66
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Mesenchymal|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA2 PCSK5 PLAGL1 SCUBE2

1.92e-05198364b086af292a508a156266c2d899ba1caf820bf61c
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA2 PCSK5 PLAGL1 SCUBE2

1.92e-051983641b90d632e59c3c47b936e829cceeb0334f05f34f
ToppCellEpithelial-Epithelial-D_(Clara-Club_cells)|Epithelial / shred on cell class and cell subclass (v4)

WFDC5 TSHZ2 PCSK6

1.33e-04123363caa1576f1b5eb592d522be61c090ac444e277ac5
ToppCellEndothelial-G|World / shred on cell class and cell subclass (v4)

RSPO3 TSHZ2 PCSK6

1.37e-041243634b72809463f2986b7d1b7ab9de633ac4d7854a92
ToppCellTCGA-Bone_and_Soft_Tissue-Primary_Tumor-Sarcoma-Conventional_Leiomyosarcoma-2|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

ZNF620 LAMA3 CELSR2

1.64e-04132363a8e7e7f38af095d63e221bcc06a1e5147bb6e467
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L5_PT-L5_PT_VISp_Krt80|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PCSK5 RSPO3 ZNF804B

1.99e-0414136340ef6d792e11fe10963d64eb0b606b90556c1a70
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

LAMA2 RSPO3 TSHZ2

2.68e-04156363363f1b661048d25895e2b8681c82894c957b29c0
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

LAMA2 RSPO3 TSHZ2

2.68e-04156363d5207dbfbcfb885557ea1378dfe6a56d7102e94a
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_6|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

ZNF665 ADAM28 ZNF540

2.68e-041563630f2147abcf31a26ee5b2f4d8c5d72232612a33f0
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_6|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ZNF665 ADAM28 ZNF540

2.68e-04156363cb87f12443fdc5538b856f765fcbac9406044e10
ToppCellPND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

BLM LAMA2 CGAS

2.84e-041593637ed659163f45e0c4df4782997c0786900c8186c8
ToppCellPND07-Endothelial-Endothelial_lymphatic|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RSPO3 TSHZ2 PCSK6

2.94e-04161363133b4fadb499e842c19f573f9cf09ce08c1d4813
ToppCellPND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RSPO3 TSHZ2 PCSK6

2.94e-04161363cb177ca10d848d0e25399ab5ebfcde1071fb94c2
ToppCellPND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RSPO3 TSHZ2 PCSK6

2.94e-041613639466b8658244116f8d21f2f88fb8c2d184b1bdf2
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-high_Fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LAMA2 MUC2 TSHZ2

3.00e-041623635f009b231f21861afee9cc0c569082e1135f929c
ToppCell368C-Fibroblasts-Fibroblast-E|368C / Donor, Lineage, Cell class and subclass (all cells)

LAMA2 RSPO3 ZNF763

3.00e-04162363e17632778a57c71d6005d3abca3a0443a92040e7
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-high_Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LAMA2 MUC2 TSHZ2

3.00e-04162363b936f8040dcd4db621ccded19237af8df7d0ed6e
ToppCell368C-Fibroblasts-Fibroblast-E-|368C / Donor, Lineage, Cell class and subclass (all cells)

LAMA2 RSPO3 ZNF763

3.00e-04162363ac4a80fd72c9311ea2b3e574c6284bbce4f2756c
ToppCellInfluenza_Severe-cDC|World / Disease group and Cell class

ADAM28 ST14 KCTD16

3.11e-04164363c984228f73b9aa1aaf948541f64f41ed874770cd
ToppCellPND10-Endothelial-Endothelial_lymphatic-Lymphatic_EC|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RSPO3 TSHZ2 PCSK6

3.11e-041643637a8e5ef52a8fd2877d59ef0696af8a7af90bbed6
ToppCellPND10-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RSPO3 TSHZ2 PCSK6

3.11e-041643635e5bd81414ea2d64f73cdef19a0a78c17bec8c18
ToppCellPND10-Endothelial-Endothelial_lymphatic|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RSPO3 TSHZ2 PCSK6

3.11e-04164363f13b8d9b7f42193f333d9a77571a1dde6bbb48d8
ToppCellPND10-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RSPO3 TSHZ2 PCSK6

3.11e-041643634cfc9f92e49f86d3639e018b35b6a60dc62f494a
ToppCellPND03-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RSPO3 TSHZ2 PCSK6

3.16e-04165363347b59aa625a8a960828b8620824d8ac48990e07
ToppCellPND03-Endothelial-Endothelial_lymphatic|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RSPO3 TSHZ2 PCSK6

3.16e-041653631890f9c33b0c5b381d57f97042da2610a093a6de
ToppCellPND03-Endothelial-Endothelial_lymphatic-Lymphatic_EC|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RSPO3 TSHZ2 PCSK6

3.16e-04165363507c89ece0a336b8e9c65b79889a714e17ddca27
ToppCellPND03-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RSPO3 TSHZ2 PCSK6

3.16e-0416536339a25be081a5d59c7cf107a997d352793d5025fb
ToppCellPND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TSHZ2 PCSK6 SMYD2

3.16e-0416536350a8513d8d2630861499393a7f102b35366bad37
ToppCell367C-Myeloid-Macrophage-FABP4+_Macrophage_3|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

LAMA2 LAMA3 TSHZ2

3.22e-04166363f416d8a322f086c769659a9fab6b460a2d546ab1
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L5_RORB_SNHG7|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RSPO3 TSHZ2 SMYD2

3.28e-041673635d89f5bcd0aaa772c1d09c2cc46fbfe0a90f9f12
ToppCelltumor_Lymph_Node_/_Brain-T/NK_cells-CD8+/CD4+_Mixed_Th|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

BLM USP18 ZNF331

3.28e-04167363c0c944eae0514dc8e00d0c2892a0792e157695ec
ToppCellfacs-Lung-EPCAM-24m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BLM RSPO3 ZNF189

3.28e-04167363961e722442d786ab15d1e490941d2be265a9057a
ToppCellfacs-Lung-EPCAM-24m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BLM RSPO3 ZNF189

3.28e-041673633760efc35d4e7e9c2da1a20f9795ddea397e2206
ToppCellSigmoid-Macrophage-Macrophage|Macrophage / Region, Cell class and subclass

ADAM28 ST14 ZNF331

3.34e-04168363bb16e135b6ae0d66615420b61edd6f62f2a3233c
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m-Mesenchymal-stromal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA2 RSPO3 PCSK6

3.39e-041693638bfa2d3bb541d02f55d7c95b8fd156c8403befca
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m-Mesenchymal|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA2 RSPO3 PCSK6

3.39e-04169363bb43abad2c049b7f4d307737347290e01b3339a3
ToppCellRA-01._Fibroblast_I|RA / Chamber and Cluster_Paper

LAMA2 TSHZ2 ZNF804B

3.39e-041693636373562ab3b1765060212a6a53d6543e7e942e80
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_ETV4|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PCSK5 TSHZ2 ST14

3.39e-04169363716e9d4c5fb99c56b76afaa5ed90bfa859fde802
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m-Mesenchymal-stromal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA2 RSPO3 PCSK6

3.39e-041693635f18e3f40a5b1b167903f37516ec8181e889c7c5
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-mLTo|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LAMA3 TSHZ2 ZNF804B

3.39e-04169363559e98216720e4babf0b0941100f1b485c35b11b
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_SEMA6D|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LAMA2 TSHZ2 SMYD2

3.45e-041703635de2f7d16a05af74ebfb1ca42d0f9c3c3524692d
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Myeloid-Granulocytic-Neutrophil-Neu_c5-GSTP1(high)OASL(low)|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

USP18 ZNF540 CGAS

3.45e-0417036307b561cd9c528bc8444c9385e1de621eee7b697e
ToppCellE16.5-samps-Epithelial-Alveolar_epithelial_precursor-Uncommitted_AE_cell|E16.5-samps / Age Group, Lineage, Cell class and subclass

LAMA3 CELSR2 ST14

3.45e-041703635a64e05c263df915085988d881808221e2c0f2e2
ToppCellPND14-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RSPO3 TSHZ2 PCSK6

3.51e-04171363686f95892c3909973c66c9a27159a070a068f175
ToppCellPND14-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RSPO3 TSHZ2 PCSK6

3.51e-04171363f7ba03e7bdb687f93782c936c7b3374cc5b3b77c
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

BLM LAMA2 TSHZ2

3.51e-04171363b92963f9f247d2e5e2e6c51c6dbf70e527cd2f55
ToppCellPND14-Endothelial-Endothelial_lymphatic|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RSPO3 TSHZ2 PCSK6

3.51e-04171363d0ac50071a3854d02113c455fcc940a6ec59bbb9
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

BLM LAMA2 TSHZ2

3.51e-04171363b0373ed8283ee1792b6a490bff93906546978593
ToppCellPND14-Endothelial-Endothelial_lymphatic-Lymphatic_EC|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RSPO3 TSHZ2 PCSK6

3.51e-04171363fbf8e9db00573adcada4b25730e191417b7c9999
ToppCell367C-Myeloid-Monocyte-CD16+_Monocyte|Monocyte / Donor, Lineage, Cell class and subclass (all cells)

LAMA2 RSPO3 CELSR2

3.57e-04172363fb8ab2576b5c38db63573a3bf46b8d9d634c4999
ToppCellEndothelial-Endothelial-G|Endothelial / shred on cell class and cell subclass (v4)

RSPO3 TSHZ2 PCSK6

3.57e-04172363644f8e42ee8d8996f6ae50cdf874559be55509fc
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RSPO3 TSHZ2 SMYD2

3.63e-04173363ee972d9cc68755926512fd3bbe1267098c67cd94
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LAMA2 SCUBE2 TSHZ2

3.63e-04173363ab6d3507301038f944ad59ccd848b5e6eeb76d04
ToppCell3'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PLAGL1 SCUBE2 TSHZ2

3.70e-041743639d22a554617a93701d0945de63cc3e7b24322c40
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PCSK5 TSHZ2 ST14

3.70e-041743637d4b860e05b5931f6f9d757a68f75ff35597a47a
ToppCell5'-Adult-LargeIntestine-Mesenchymal-stromal_related|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LAMA2 RSPO3 SCUBE2

3.76e-04175363b8995e7ada85ba959f06264a0295b61e390c4e6c
ToppCellfacs-Lung-ENDOMUCIN-18m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RSPO3 TSHZ2 PCSK6

3.76e-041753639d082ba0e350162aa6e71b668be074b12a27c7ab
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_B-B_cell-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

ADAM28 ZNF260 ZNF189

3.76e-0417536369ed3c7c45df6bef70f5f2ff003531160bf3b32b
ToppCellP15-Endothelial-lymphatic_endothelial_cell-endothelial_cell_of_lymphatic_vessel|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

RSPO3 TSHZ2 PCSK6

3.76e-0417536384d252f3e432231687613299bbea14978bb4b06b
ToppCell5'-Adult-LargeIntestine-Mesenchymal-stromal_related-T_reticular|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LAMA2 RSPO3 SCUBE2

3.76e-041753637ae76bd3b4f610b2f98716a4456437cd3696b686
ToppCellfacs-Lung-ENDOMUCIN-18m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RSPO3 TSHZ2 PCSK6

3.76e-04175363f641f34b52aec5d047430a6f9d026e915da6c11d
ToppCellP15-Endothelial-lymphatic_endothelial_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

RSPO3 TSHZ2 PCSK6

3.76e-04175363a00c6fa9b33640710dd05a3799031147196f0986
ToppCellfacs-Lung-Endomucin-24m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RSPO3 TSHZ2 PCSK6

3.82e-04176363b81e5d23b31cefc8d374ef403e21acc390c14a80
ToppCellfacs-Lung-Endomucin-24m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RSPO3 TSHZ2 PCSK6

3.82e-04176363057d2759fdc67176c25802b57a78064d8cc93205
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_PRSS12|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LAMA2 SMYD2 ZNF804B

3.88e-04177363f902600c639087664316b3cf30cab243bc3d1c5c
ToppCellLPS-antiTNF-Epithelial_alveolar-Mes-like-AT1_Progenitor|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ZNF397 ST14 CGAS

3.88e-04177363164ffbbf798defa3728197deb1a14b661490e525
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Myeloid-Dendritic-conventional_dendritic_cell-DC_c1-CLEC9A|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ADAM28 ST14 KCTD16

3.88e-04177363e68ad19963a3d8917dfdb81127a41c4fcbe61dd5
ToppCell(3)_Chondrocytes-(32)_Chondro-prehyper-2|World / Cell class and subclass of bone marrow stroma cells in homeostatis

BLM RSPO3 PLAGL1

3.95e-04178363c569a406c3ae183a278d8540e8eba58f4f26c5b0
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LAMA2 TSHZ2 ZNF804B

3.95e-041783630e1bedf991189d0ef9b40dac9281bdf4739333a1
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LAMA2 SMYD2 ZNF804B

4.01e-041793638766a5a066091879f521acfc612abf563ff78808
ToppCell10x3'2.3-week_12-13-Myeloid_macrophage-stroma-erythroid_macrophage|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

CELSR2 TSHZ2 ZNF260

4.01e-04179363c17ae394b855f01f8ca1765c416fd8b34a96e60b
ToppCellLA-01._Fibroblast_I|LA / Chamber and Cluster_Paper

LAMA2 TSHZ2 PCSK6

4.01e-04179363dcb6ec9ae72b13fe388b72dace2815293fafe8ee
DiseaseC-reactive protein measurement, high density lipoprotein cholesterol measurement

RSPO3 CELSR2

6.65e-0434332EFO_0004458, EFO_0004612
Diseaseapolipoprotein B measurement

PCSK5 RSPO3 ZNF101 CELSR2 PCSK6

7.95e-04663335EFO_0004615
Diseasefree cholesterol to total lipids in IDL percentage

CELSR2 PCSK6

1.06e-0343332EFO_0022278
Diseasecholesteryl esters to total lipids in small HDL percentage

CELSR2 PCSK6

1.06e-0343332EFO_0022254
Diseasedimethylglycine measurement

PCSK6 ZNF804B

1.22e-0346332EFO_0010476
Diseasecholesteryl esters to total lipids in small VLDL percentage

CELSR2 PCSK6

1.38e-0349332EFO_0022256
Diseaselow density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio

RSPO3 CELSR2 PCSK6

1.44e-03200333EFO_0004611, EFO_0020945
Diseasecholesterol to total lipids in small HDL percentage

CELSR2 PCSK6

1.49e-0351332EFO_0022240
Diseasecholesterol to total lipids in small VLDL percentage

CELSR2 PCSK6

1.49e-0351332EFO_0022242
Diseaseglucose-dependent insulinotropic peptide measurement

SETDB1 ADAM28

1.61e-0353332EFO_0008464
Diseasetotal lipids in medium VLDL

RSPO3 CELSR2

1.67e-0354332EFO_0022153
Diseasetriglycerides in medium VLDL measurement

RSPO3 CELSR2

1.74e-0355332EFO_0022155
Diseasecholesterol to total lipids in large HDL percentage

RSPO3 CELSR2

1.74e-0355332EFO_0022234
Diseaseisoleucine measurement

LAMA2 ZNF804B

1.80e-0356332EFO_0009793
Diseasetriglycerides to total lipids in small VLDL percentage

CELSR2 PCSK6

1.93e-0358332EFO_0022338
Diseasevery low density lipoprotein cholesterol measurement, cholesterol:total lipids ratio

RSPO3 CELSR2 PCSK6

1.94e-03222333EFO_0008317, EFO_0020943
Diseasecholesterol in medium HDL measurement

RSPO3 CELSR2

1.99e-0359332EFO_0021903
Diseasephospholipids in VLDL measurement

RSPO3 CELSR2

1.99e-0359332EFO_0022301
Diseasetriglycerides:total lipids ratio, very low density lipoprotein cholesterol measurement

RSPO3 CELSR2 PCSK6

2.02e-03225333EFO_0008317, EFO_0020947
Diseasetotal lipids in VLDL measurement

RSPO3 CELSR2

2.06e-0360332EFO_0022314
Diseasephospholipids:total lipids ratio

RSPO3 CELSR2 PCSK6

2.07e-03227333EFO_0020946
Diseasefree cholesterol in VLDL measurement

RSPO3 CELSR2

2.13e-0361332EFO_0022276
Diseasetriglycerides in medium LDL measurement

RSPO3 CELSR2

2.20e-0362332EFO_0022322
Diseasetriglycerides to total lipids in medium VLDL percentage

RSPO3 CELSR2

2.27e-0363332EFO_0022335
Diseasecholesterol to total lipids in medium VLDL percentage

RSPO3 CELSR2

2.27e-0363332EFO_0022239
Diseasecholesteryl esters to total lipids in medium VLDL percentage

RSPO3 CELSR2

2.34e-0364332EFO_0022253
Diseasevery low density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio

RSPO3 CELSR2 PCSK6

2.39e-03239333EFO_0008317, EFO_0020945
Diseasetriglycerides in small LDL measurement

RSPO3 CELSR2

2.41e-0365332EFO_0022323
Diseasecholesterol in large VLDL measurement

RSPO3 CELSR2

2.41e-0365332EFO_0021902
Diseasecholesterol in very large VLDL measurement

RSPO3 CELSR2

2.41e-0365332EFO_0022230
Diseasecholesteryl esters:total lipids ratio, high density lipoprotein cholesterol measurement

RSPO3 CELSR2 PCSK6

2.51e-03243333EFO_0004612, EFO_0020944
Diseasetotal lipids in small VLDL

RSPO3 CELSR2

2.56e-0367332EFO_0022148
Diseasetotal lipids in large VLDL

RSPO3 CELSR2

2.56e-0367332EFO_0022175
Diseasefree cholesterol in large VLDL measurement

RSPO3 CELSR2

2.64e-0368332EFO_0022265
DiseaseAbdominal Aortic Aneurysm

CELSR2 SMYD2

2.64e-0368332EFO_0004214
Diseasetriglycerides to total lipids in very small VLDL percentage

RSPO3 CELSR2

2.72e-0369332EFO_0022341
Diseasecholesterol in very large HDL measurement

RSPO3 CELSR2

2.72e-0369332EFO_0022229
Diseasefree cholesterol to total lipids in large LDL percentage

RSPO3 CELSR2

3.12e-0374332EFO_0022280
Diseasevery low density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio

RSPO3 CELSR2 PCSK6

3.17e-03264333EFO_0008317, EFO_0020944

Protein segments in the cluster

PeptideGeneStartEntry
STNCSSKCKGHAVCD

ADAM28

626

Q9UKQ2
DPDCNKTSGECHCKE

CELSR2

1896

Q9HCU4
GKSKTCCENKEEKCC

CGAS

391

Q8N884
LCSKCSPHFSDCKKS

ECD

311

O95905
DKENPSGCSECKCHK

LAMA3

621

Q16787
SGCSECKCHKAGTVS

LAMA3

626

Q16787
SHCDCCCKNGKGDKE

KCTD16

286

Q68DU8
KTKDTHPESCCSSEK

GGNBP2

576

Q9H3C7
GEGEKFNCEKCHESC

PCSK5

1661

Q92824
DESQKNCLKCHPSCK

PCSK6

791

P29122
NCLKCHPSCKKCVDE

PCSK6

796

P29122
KAQALDHSCSCCKEE

MUC2

5111

Q02817
DHSCSCCKEEKTSQR

MUC2

5116

Q02817
LTKTECEACNCHGKA

LAMA2

336

P24043
VAKACDEGHCTAKDC

IVD

346

P26440
KKHPDVSCDNCCKTK

BLM

1056

P54132
PSCTESDSCKRDCKK

KRTAP16-1

451

A8MUX0
SCMNKDHGCSHICKE

SCUBE2

176

Q9NQ36
TKEKKHQCDHCERCF

PLAGL1

151

Q9UM63
CKDGCRDKSKCACHQ

SETDB1

731

Q15047
KCKECGKCFTQNSHL

ZNF665

291

Q9H7R5
CHKDSDCSGKKRCCH

WFDC5

96

Q8TCV5
PNSEEKCHKCEECGK

ZNF189

141

O75820
QKIHTGEKSCKCEKC

ZNF540

206

Q8NDQ6
DKCKCCRFANKDTHL

ZNF804B

261

A4D1E1
GEKSHECTECGKVCS

ZNF260

51

Q3ZCT1
KCLSKSQQCNGKDDC

ST14

536

Q9Y5Y6
KCHTGEKSFECKECG

ZNF620

216

Q6ZNG0
AKSYECKECGKACNH

ZNF331

436

Q9NQX6
DINKCTKCKADCDTC

RSPO3

91

Q9BXY4
AEEDTDSKFKCKLCC

TSHZ2

986

Q9NRE2
ECKECGKTFCQKSHL

ZNF717

871

Q9BY31
ELSSKSKCFCENCGK

USP41

221

Q3LFD5
THTTEKACECKECGK

ZNF25

111

P17030
SHQCQECGKKLSCSS

ZNF101

281

Q8IZC7
EKACKCNECGKAFSQ

ZNF397

366

Q8NF99
KSTHSGEKNCKCDEC

ZFP62

216

Q8NB50
ELSSKSKCFCENCGK

USP18

221

Q9UMW8
TCECQECTTKDKDKA

SMYD2

261

Q9NRG4
HTGEKPCECSKCNKA

ZNF763

306

Q0D2J5