Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
PathwayREACTOME_TCF_DEPENDENT_SIGNALING_IN_RESPONSE_TO_WNT

KMT2D WNT1

7.38e-0415842MM14791
PathwayREACTOME_TCF_DEPENDENT_SIGNALING_IN_RESPONSE_TO_WNT

KMT2D WNT1

1.60e-0323342M27099
PathwayREACTOME_SIGNALING_BY_WNT

KMT2D WNT1

1.68e-0323942MM14756
PathwayREACTOME_SIGNALING_BY_WNT

KMT2D WNT1

3.18e-0333042M7847
Pubmed

Multiple epigenetic maintenance factors implicated by the loss of Mll2 in mouse development.

KMT2D WNT1

7.29e-0777216540515
Pubmed

MLL4 is required after implantation, whereas MLL3 becomes essential during late gestation.

KMT2D WNT1

1.83e-05337232439762
Pubmed

Widespread and dynamic translational control of red blood cell development.

MFF DDX41

1.77e-041027227899360
CytobandEnsembl 112 genes in cytogenetic band chr12q13

KMT2D WNT1

1.73e-0342372chr12q13
CoexpressionDELACROIX_RARG_BOUND_MEF

AEBP1 MIDN WNT1

9.07e-0536673M2461
CoexpressionDELACROIX_RARG_BOUND_MEF

AEBP1 MIDN WNT1

9.98e-0537873MM1077
ToppCelltumor_Lymph_Node_/_Brain-Myeloid_cells-pDCs|Myeloid_cells / Location, Cell class and cell subclass

POLE AEBP1

2.48e-041567219472ef1642c2ad333aa3ce3675a25c6ab1d4556
ToppCelldroplet-Kidney-nan-18m-Endothelial-kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

POLE WNT1

3.15e-04176725386386619cf173939d3c117b20e6f27ab397993
ToppCelldroplet-Kidney-nan-18m-Endothelial-Pecam____kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

POLE WNT1

3.15e-0417672820edade963768e4bfd86b554da4cd7100567ac8
ToppCellfacs-Pancreas-Exocrine-18m-Mesenchymal|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AEBP1 WNT1

3.34e-0418172269b39ac65790061d54eab47a8eeb024403f0348
ToppCellfacs-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AEBP1 WNT1

3.34e-0418172cd4f744b6b64ba6c22ec07afd1d3058a2546909d
ToppCellfacs-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AEBP1 WNT1

3.34e-0418172c8395ae872aa80b3ae1ab7c53e57b3ca15aeb0e2
ToppCellwk_15-18-Epithelial-Distal_epithelial_progenitor-epi-tip_intermediate|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

POLE KMT2D

3.48e-0418572636505a3d96f75d951ab42bcf8af6ae07abc732d
ToppCellCV-Severe-3|Severe / Virus stimulation, Condition and Cluster

POLE WNT1

3.56e-041877268cb43a73945f5e252530da25613f6b3f484b4d5
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m-Epithelial-basal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AEBP1 MIDN

3.71e-04191728691eba35793e4e90f93d50c2145847ee51289f7
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m-Epithelial-basal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AEBP1 MIDN

3.71e-04191722f733d510a4862565a817f59829d8387d7ea26d9
ToppCellfacs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l20-25|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

AEBP1 WNT1

3.83e-04194727b6ec45adb7ece3c8a7b78c5782413b5825effe2
ToppCellfacs-Mammary_Gland-Mammary_Gland-18m-Epithelial-basal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AEBP1 MIDN

3.87e-0419572f41a68b7c2621594db8d8952e301eeadc96be26f
ToppCellSigmoid-T_cell-Tcm|T_cell / Region, Cell class and subclass

AEBP1 WNT1

4.03e-0419972acdf95f4d58df47690f4ae254245bc618f9ac07e
ToppCellSkin-Mesangial|Skin / Skin and Kidney Cells in Lupus Nephritis Patients.

AEBP1 WNT1

4.03e-0419972bcb78838a91cc7828680fb413fbacdb091c5fac0
ToppCellmLN-Dendritic_cell-cDC2|Dendritic_cell / Region, Cell class and subclass

DDX41 MIDN

4.07e-0420072e3f7852aaa26a9b3e626d85e40afde799e873045
Drug2',3'-dideoxycytidine (ddC

POLE AEBP1

2.28e-047672CID000005718
DrugNSC740137

DDX41 AEBP1

4.19e-0410372CID000003817
DrugT694

MFF DDX41

5.13e-0411472CID000000872
DrugNSC401575

POLE WNT1

6.57e-0412972CID000003165
Drug6-thioguanine

POLE DDX41

6.67e-0413072CID002723601
Drugheparin pentasaccharide

POLE DDX41

8.17e-0414472CID000444410
DrugAzitidin

POLE AEBP1

1.12e-0316972CID000005726
Drug2-propylpentanoic acid; Up 200; 500uM; HL60; HT_HG-U133A

KMT2D WNT1

1.42e-03190722700_UP
DrugClomipramine hydrochloride [17321-77-6]; Up 200; 11.4uM; PC3; HT_HG-U133A

KMT2D WNT1

1.43e-03191724487_UP
DrugIsradipine [75695-93-1]; Up 200; 10.8uM; MCF7; HT_HG-U133A

AEBP1 WNT1

1.52e-03197725447_UP
DrugST021200; Up 200; 10uM; MCF7; HT_HG-U133A

AEBP1 WNT1

1.54e-03198727488_UP
DrugBendroflumethiazide [73-48-3]; Up 200; 9.4uM; MCF7; HT_HG-U133A

AEBP1 WNT1

1.55e-03199723934_UP
DrugTyloxapol [25301-02-4]; Up 200; 4uM; MCF7; HT_HG-U133A

KMT2D WNT1

1.55e-03199726452_UP
Diseaselung squamous cell carcinoma (is_implicated_in)

POLE KMT2D

1.33e-052472DOID:3907 (is_implicated_in)
Diseaselung non-small cell carcinoma (is_implicated_in)

POLE KMT2D

4.56e-0413972DOID:3908 (is_implicated_in)
Diseaseattention deficit hyperactivity disorder, autism spectrum disorder, intelligence

KMT2D WNT1

3.64e-0339872EFO_0003756, EFO_0003888, EFO_0004337
Diseasereaction time measurement

KMT2D WNT1

9.68e-0365872EFO_0008393

Protein segments in the cluster

PeptideGeneStartEntry
RRLQQRRLQHRLRLR

AEBP1

1016

Q8IUX7
LRRQIIKLNRRLQLL

MFF

296

Q9GZY8
LQARQRLARRKRQRL

POLE

1281

Q07864
QRRQLLLQKLLQRRR

DDX41

41

Q9UJV9
QLLLQQKRLRRKARR

MIDN

396

Q504T8
LRQLLRRRKKRRQGR

nan

321

A8MX80
LRQLLRRRKKRQQVR

nan

321

A8MUA0
LQLLSRKQRRLIRQN

WNT1

61

P04628
RQRQRLRELLIRQQI

KMT2D

2681

O14686