Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ZNF449 ZBTB37 ZNF444 ZNF536 ZNF320 ZNF672 ZNF497 ZNF33A ZBTB48 ZSCAN22 ZNF366 ZNF764 ZNF253 ZNF596 ZNF335 ZNF575 ZNF205 NTN1 ZNF213 ZNF362 ZNF236 TRIM24 ZNF281 ZNF879 ZNF441 ZFX IKZF5	6.86e-18	1459	51	27	GO:0000977
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ZNF449 ZBTB37 ZNF444 ZNF536 ZNF320 ZNF497 ZNF33A ZBTB48 ZSCAN22 ZNF366 ZNF764 ZNF253 ZNF335 ZNF575 ZNF205 NTN1 ZNF213 ZNF362 ZNF236 TRIM24 ZNF281 ZNF879 ZFX IKZF5	4.25e-16	1244	51	24	GO:0000978
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	ZNF449 ZBTB37 ZNF444 ZNF536 ZNF320 ZNF497 ZNF33A ZBTB48 ZSCAN22 ZNF366 ZNF764 ZNF253 ZNF335 ZNF575 ZNF205 NTN1 ZNF213 ZNF362 ZNF236 TRIM24 ZNF281 ZNF879 ZFX IKZF5	6.89e-16	1271	51	24	GO:0000987
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	ZNF449 ZBTB37 ZNF444 ZNF536 ZNF320 ZNF672 ZNF33A ZBTB48 ZSCAN22 ZNF764 ZNF253 ZNF596 ZNF575 ZBTB40 ZNF205 NTN1 ZNF213 ZNF236 ZNF281 ZNF879 ZNF441 ZFX IKZF5	8.33e-14	1412	51	23	GO:0000981
GeneOntologyMolecularFunction	extracellular matrix structural constituent	SLIT2 FRAS1 THBS2 LAMB3 NTN1	1.16e-04	188	51	5	GO:0005201
GeneOntologyMolecularFunction	DNA-binding transcription repressor activity, RNA polymerase II-specific	ZBTB37 ZNF536 ZNF205 ZNF281 IKZF5	1.32e-03	320	51	5	GO:0001227
GeneOntologyMolecularFunction	DNA-binding transcription repressor activity	ZBTB37 ZNF536 ZNF205 ZNF281 IKZF5	1.43e-03	326	51	5	GO:0001217
GeneOntologyCellularComponent	basement membrane	LAMB4 FRAS1 THBS2 LAMB3 NTN1	1.30e-05	122	52	5	GO:0005604
GeneOntologyCellularComponent	extracellular matrix	SLIT2 LAMB4 FRAS1 THBS2 FCGBP LAMB3 NTN1	1.14e-03	656	52	7	GO:0031012
GeneOntologyCellularComponent	external encapsulating structure	SLIT2 LAMB4 FRAS1 THBS2 FCGBP LAMB3 NTN1	1.16e-03	658	52	7	GO:0030312
GeneOntologyCellularComponent	collagen-containing extracellular matrix	SLIT2 LAMB4 FRAS1 THBS2 LAMB3 NTN1	1.96e-03	530	52	6	GO:0062023
MousePheno	abnormal ureteric bud morphology	SLIT2 FRAS1 GEN1 GDF11	7.20e-06	57	31	4	MP:0006032
MousePheno	impaired branching involved in ureteric bud morphogenesis	FRAS1 GEN1 GDF11	9.94e-05	41	31	3	MP:0004936
MousePheno	abnormal urinary system development	SLIT2 FRAS1 GEN1 GDF11	1.00e-04	111	31	4	MP:0003942
MousePheno	abnormal branching involved in ureteric bud morphogenesis	FRAS1 GEN1 GDF11	1.32e-04	45	31	3	MP:0010981
Domain	Znf_C2H2/integrase_DNA-bd	ZNF449 ZBTB37 ZNF444 ZNF536 ZNF469 ZNF320 ZNF672 ZNF497 ZNF33A ZBTB48 ZSCAN22 ZNF366 ZNF764 ZNF253 ZNF596 ZNF335 ZNF575 ZBTB40 ZNF205 ZNF213 ZNF362 ZNF236 ZNF281 ZNF879 ZNF441 ZFX IKZF5	2.99e-25	694	52	27	IPR013087
Domain	-	ZNF449 ZBTB37 ZNF444 ZNF536 ZNF320 ZNF672 ZNF497 ZNF33A ZBTB48 ZSCAN22 ZNF366 ZNF764 ZNF253 ZNF596 ZNF335 ZNF575 ZBTB40 ZNF205 ZNF213 ZNF362 ZNF236 ZNF281 ZNF879 ZNF441 ZFX IKZF5	4.78e-24	679	52	26	3.30.160.60
Domain	ZINC_FINGER_C2H2_2	ZNF449 ZBTB37 ZNF444 ZNF536 ZNF469 ZNF320 ZNF672 ZNF497 ZNF33A ZBTB48 ZSCAN22 ZNF366 ZNF764 ZNF253 ZNF596 ZNF335 ZNF575 ZBTB40 ZNF205 ZNF213 ZNF362 ZNF236 ZNF281 ZNF879 ZNF441 ZFX IKZF5	5.57e-24	775	52	27	PS50157
Domain	ZINC_FINGER_C2H2_1	ZNF449 ZBTB37 ZNF444 ZNF536 ZNF469 ZNF320 ZNF672 ZNF497 ZNF33A ZBTB48 ZSCAN22 ZNF366 ZNF764 ZNF253 ZNF596 ZNF335 ZNF575 ZBTB40 ZNF205 ZNF213 ZNF362 ZNF236 ZNF281 ZNF879 ZNF441 ZFX IKZF5	5.96e-24	777	52	27	PS00028
Domain	zf-C2H2	ZNF449 ZBTB37 ZNF444 ZNF536 ZNF469 ZNF320 ZNF672 ZNF497 ZNF33A ZBTB48 ZSCAN22 ZNF366 ZNF764 ZNF253 ZNF596 ZNF335 ZNF575 ZBTB40 ZNF205 ZNF213 ZNF362 ZNF236 ZNF281 ZNF879 ZNF441 ZFX	8.06e-24	693	52	26	PF00096
Domain	Znf_C2H2-like	ZNF449 ZBTB37 ZNF444 ZNF536 ZNF469 ZNF320 ZNF672 ZNF497 ZNF33A ZBTB48 ZSCAN22 ZNF366 ZNF764 ZNF253 ZNF596 ZNF335 ZNF575 ZBTB40 ZNF205 ZNF213 ZNF362 ZNF236 ZNF281 ZNF879 ZNF441 ZFX IKZF5	1.13e-23	796	52	27	IPR015880
Domain	Znf_C2H2	ZNF449 ZBTB37 ZNF444 ZNF536 ZNF469 ZNF320 ZNF672 ZNF497 ZNF33A ZBTB48 ZSCAN22 ZNF366 ZNF764 ZNF253 ZNF596 ZNF335 ZNF575 ZBTB40 ZNF205 ZNF213 ZNF362 ZNF236 ZNF281 ZNF879 ZNF441 ZFX IKZF5	1.52e-23	805	52	27	IPR007087
Domain	ZnF_C2H2	ZNF449 ZBTB37 ZNF444 ZNF536 ZNF469 ZNF320 ZNF672 ZNF497 ZNF33A ZBTB48 ZSCAN22 ZNF366 ZNF764 ZNF253 ZNF596 ZNF335 ZNF575 ZBTB40 ZNF205 ZNF213 ZNF362 ZNF236 ZNF281 ZNF879 ZNF441 ZFX IKZF5	1.67e-23	808	52	27	SM00355
Domain	zf-C2H2_6	ZNF449 ZNF320 ZNF672 ZNF497 ZBTB48 ZSCAN22 ZNF366 ZNF253 ZNF236 ZNF879	1.32e-08	314	52	10	PF13912
Domain	KRAB	ZNF320 ZNF33A ZNF764 ZNF253 ZNF596 ZNF205 ZNF213 ZNF879 ZNF441	5.62e-07	358	52	9	PS50805
Domain	KRAB	ZNF320 ZNF33A ZNF764 ZNF253 ZNF596 ZNF205 ZNF213 ZNF879 ZNF441	5.62e-07	358	52	9	PF01352
Domain	KRAB	ZNF320 ZNF33A ZNF764 ZNF253 ZNF596 ZNF205 ZNF213 ZNF879 ZNF441	7.23e-07	369	52	9	SM00349
Domain	KRAB	ZNF320 ZNF33A ZNF764 ZNF253 ZNF596 ZNF205 ZNF213 ZNF879 ZNF441	7.40e-07	370	52	9	IPR001909
Domain	LAMININ_NTER	LAMB4 LAMB3 NTN1	1.11e-05	16	52	3	PS51117
Domain	Laminin_N	LAMB4 LAMB3 NTN1	1.11e-05	16	52	3	PF00055
Domain	Laminin_N	LAMB4 LAMB3 NTN1	1.11e-05	16	52	3	IPR008211
Domain	LamNT	LAMB4 LAMB3 NTN1	1.11e-05	16	52	3	SM00136
Domain	SCAN	ZNF449 ZNF444 ZSCAN22 ZNF213	1.76e-05	56	52	4	SM00431
Domain	SCAN_BOX	ZNF449 ZNF444 ZSCAN22 ZNF213	2.03e-05	58	52	4	PS50804
Domain	SCAN	ZNF449 ZNF444 ZSCAN22 ZNF213	2.03e-05	58	52	4	PF02023
Domain	SCAN_dom	ZNF449 ZNF444 ZSCAN22 ZNF213	2.03e-05	58	52	4	IPR003309
Domain	Retrov_capsid_C	ZNF449 ZNF444 ZSCAN22 ZNF213	2.17e-05	59	52	4	IPR008916
Domain	EGF_LAM_2	LAMB4 LAMB3 NTN1	7.84e-05	30	52	3	PS50027
Domain	EGF_LAM_1	LAMB4 LAMB3 NTN1	7.84e-05	30	52	3	PS01248
Domain	Laminin_EGF	LAMB4 LAMB3 NTN1	1.25e-04	35	52	3	PF00053
Domain	EGF_Lam	LAMB4 LAMB3 NTN1	1.25e-04	35	52	3	SM00180
Domain	VWC	FRAS1 THBS2 FCGBP	1.60e-04	38	52	3	SM00214
Domain	Laminin_EGF	LAMB4 LAMB3 NTN1	1.60e-04	38	52	3	IPR002049
Domain	VWF_dom	FRAS1 THBS2 FCGBP	2.16e-04	42	52	3	IPR001007
Domain	Fol_N	SLIT2 FCGBP	4.11e-04	11	52	2	IPR003645
Domain	FOLN	SLIT2 FCGBP	4.11e-04	11	52	2	SM00274
Domain	EGF_1	SLIT2 LAMB4 THBS2 LAMB3 NTN1	7.02e-04	255	52	5	PS00022
Domain	EGF-like_CS	SLIT2 LAMB4 THBS2 LAMB3 NTN1	7.80e-04	261	52	5	IPR013032
Domain	EGF_2	SLIT2 LAMB4 THBS2 LAMB3 NTN1	8.35e-04	265	52	5	PS01186
Domain	VWC_out	FRAS1 FCGBP	1.26e-03	19	52	2	SM00215
Domain	PHD	TCF20 TRIM24 NSD3	1.95e-03	89	52	3	SM00249
Domain	Znf_PHD	TCF20 TRIM24 NSD3	2.08e-03	91	52	3	IPR001965
Domain	ZF_PHD_2	TCF20 TRIM24 NSD3	2.35e-03	95	52	3	PS50016
Domain	ZF_PHD_1	TCF20 TRIM24 NSD3	2.42e-03	96	52	3	PS01359
Domain	VWC	FRAS1 THBS2	2.74e-03	28	52	2	PF00093
Domain	EGF	SLIT2 FRAS1 THBS2 FCGBP	4.12e-03	235	52	4	SM00181
Domain	VWFC_1	FRAS1 THBS2	4.51e-03	36	52	2	PS01208
Domain	VWFC_2	FRAS1 THBS2	5.01e-03	38	52	2	PS50184
Domain	EGF-like_dom	SLIT2 FRAS1 THBS2 FCGBP	5.06e-03	249	52	4	IPR000742
Domain	BTB	ZBTB37 ZBTB48 ZBTB40	5.80e-03	131	52	3	PF00651
Domain	ZnF_C3H1	ZC3H14 MBNL3	7.90e-03	48	52	2	SM00356
Domain	Znf_FYVE_PHD	TCF20 TRIM24 NSD3	7.97e-03	147	52	3	IPR011011
Domain	BTB	ZBTB37 ZBTB48 ZBTB40	1.00e-02	160	52	3	PS50097
Domain	Laminin_G	SLIT2 THBS2	1.14e-02	58	52	2	IPR001791
Domain	Znf_CCCH	ZC3H14 MBNL3	1.14e-02	58	52	2	IPR000571
Domain	ZF_C3H1	ZC3H14 MBNL3	1.14e-02	58	52	2	PS50103
Domain	BTB	ZBTB37 ZBTB48 ZBTB40	1.38e-02	180	52	3	SM00225
Domain	Zinc_finger_PHD-type_CS	TRIM24 NSD3	1.41e-02	65	52	2	IPR019786
Pubmed	Identification of the SOX2 Interactome by BioID Reveals EP300 as a Mediator of SOX2-dependent Squamous Differentiation and Lung Squamous Cell Carcinoma Growth.	ZNF536 TCF20 ZNF362 TRIM24 ZNF281	1.63e-07	83	52	5	28794006
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	ZBTB37 TCF20 ZBTB48 ZNF764 ZNF205 ZNF236 TRIM24 MBNL3 CRIP2 IKZF5	2.84e-07	808	52	10	20412781
Pubmed	USP7 Regulates Cytokinesis through FBXO38 and KIF20B.	ZNF536 ZBTB40 ZNF362 TRIM24 ZNF281	8.68e-07	116	52	5	30804394
Pubmed	Aberrant axonal projections from mammillary bodies in Pax6 mutant mice: possible roles of Netrin-1 and Slit 2 in mammillary projections.	SLIT2 NTN1	2.19e-06	2	52	2	19115401
Pubmed	Slit proteins bind Robo receptors and have an evolutionarily conserved role in repulsive axon guidance.	SLIT2 NTN1	6.57e-06	3	52	2	10102268
Pubmed	Regulation of Axon Guidance by Slit2 and Netrin-1 Signaling in the Lacrimal Gland of Aqp5 Knockout Mice.	SLIT2 NTN1	6.57e-06	3	52	2	37707834
Pubmed	Acetylation-Mimic Mutation of TRIM28-Lys304 to Gln Attenuates the Interaction with KRAB-Zinc-Finger Proteins and Affects Gene Expression in Leukemic K562 Cells.	ZNF320 ZNF33A ZNF764 ZNF253 ZNF441	7.70e-06	181	52	5	37372979
Pubmed	Emergent growth cone responses to combinations of Slit1 and Netrin 1 in thalamocortical axon topography.	SLIT2 NTN1	2.19e-05	5	52	2	22000108
Pubmed	Slit antagonizes netrin-1 attractive effects during the migration of inferior olivary neurons.	SLIT2 NTN1	3.28e-05	6	52	2	12051827
Pubmed	Slit2 and netrin 1 act synergistically as adhesive cues to generate tubular bi-layers during ductal morphogenesis.	SLIT2 NTN1	3.28e-05	6	52	2	16439476
Pubmed	Slit/Robo-mediated chemorepulsion of vagal sensory axons in the fetal gut.	SLIT2 NTN1	3.28e-05	6	52	2	23161783
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	ZNF444 ZNF536 TRAF2 TCF20 GAS2L3 TRIM24 ZNF281	4.42e-05	638	52	7	31182584
Pubmed	Zfp281 Shapes the Transcriptome of Trophoblast Stem Cells and Is Essential for Placental Development.	ZNF281 LIN28A	4.58e-05	7	52	2	31067460
Pubmed	The GLI-Kruppel family of human genes.	ZBTB48 ZSCAN22	4.58e-05	7	52	2	2850480
Pubmed	A census of human transcription factors: function, expression and evolution.	ZNF444 ZBTB48 ZNF335 ZNF205 ZNF236 ZNF281 MBNL3 ZFX	5.70e-05	908	52	8	19274049
Pubmed	Trio GEF mediates RhoA activation downstream of Slit2 and coordinates telencephalic wiring.	SLIT2 NTN1	6.10e-05	8	52	2	30177526
Pubmed	K63-linked polyubiquitination of transcription factor IRF1 is essential for IL-1-induced production of chemokines CXCL10 and CCL5.	MBTPS1 TRAF2	6.10e-05	8	52	2	24464131
Pubmed	Motor axons are guided to exit points in the spinal cord by Slit and Netrin signals.	SLIT2 NTN1	6.10e-05	8	52	2	28986144
Pubmed	A molecular program for contralateral trajectory: Rig-1 control by LIM homeodomain transcription factors.	SLIT2 NTN1	6.10e-05	8	52	2	18701067
Pubmed	Pioneer midbrain longitudinal axons navigate using a balance of Netrin attraction and Slit repulsion.	SLIT2 NTN1	7.84e-05	9	52	2	25056828
Pubmed	Cooperative slit and netrin signaling in contralateralization of the mouse trigeminothalamic pathway.	SLIT2 NTN1	7.84e-05	9	52	2	22806432
Pubmed	Directional guidance of interneuron migration to the cerebral cortex relies on subcortical Slit1/2-independent repulsion and cortical attraction.	SLIT2 NTN1	9.79e-05	10	52	2	12642493
Pubmed	ZBTB20 is crucial for the specification of a subset of callosal projection neurons and astrocytes in the mammalian neocortex.	ZBTB37 ZBTB48 ZBTB40	1.17e-04	63	52	3	34351428
Pubmed	Heparan sulfate regulates intraretinal axon pathfinding by retinal ganglion cells.	SLIT2 NTN1	1.20e-04	11	52	2	21743013
Pubmed	Sall1 balances self-renewal and differentiation of renal progenitor cells.	ZNF536 FRAS1 LIN28A	1.41e-04	67	52	3	24550112
Pubmed	A selective defect in the glial wedge as part of the neuroepithelium disruption in hydrocephalus development in the mouse hyh model is associated with complete corpus callosum dysgenesis.	SLIT2 NTN1	1.69e-04	13	52	2	38450283
Pubmed	Developmental guidance of the retroflex tract at its bending point involves Robo1-Slit2-mediated floor plate repulsion.	SLIT2 NTN1	1.69e-04	13	52	2	25366972
Pubmed	Association of polymorphisms in the SLIT2 axonal guidance gene with anger in suicide attempters.	SLIT2 NTN1	1.97e-04	14	52	2	20029409
Pubmed	Motor neuron cell bodies are actively positioned by Slit/Robo repulsion and Netrin/DCC attraction.	SLIT2 NTN1	1.97e-04	14	52	2	25530182
Pubmed	A simple method for 3D analysis of immunolabeled axonal tracts in a transparent nervous system.	SLIT2 NTN1	2.27e-04	15	52	2	25456121
Pubmed	Phenotypic analysis of mice completely lacking netrin 1.	SLIT2 NTN1	2.27e-04	15	52	2	26395479
Pubmed	Transcriptome-based systematic identification of extracellular matrix proteins.	FRAS1 LAMB3 NTN1	2.30e-04	79	52	3	18757743
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	SLIT2 ZNF536 TRAF2 ZNF469 ZNF362 TRIM24 ZNF281 NSD3	2.36e-04	1116	52	8	31753913
Pubmed	BARHL2 transcription factor regulates the ipsilateral/contralateral subtype divergence in postmitotic dI1 neurons of the developing spinal cord.	SLIT2 NTN1	2.60e-04	16	52	2	22307612
Pubmed	Tail Bud Progenitor Activity Relies on a Network Comprising Gdf11, Lin28, and Hox13 Genes.	GDF11 LIN28A	2.60e-04	16	52	2	30661984
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	TCF20 ZBTB40 ZNF362 TRIM24 ZNF281 NSD3	2.86e-04	608	52	6	36089195
Pubmed	Sensory and spinal inhibitory dorsal midline crossing is independent of Robo3.	SLIT2 NTN1	2.94e-04	17	52	2	26257608
Pubmed	Dual origins of the mammalian accessory olfactory bulb revealed by an evolutionarily conserved migratory stream.	SLIT2 NTN1	2.94e-04	17	52	2	23292680
Pubmed	The role of floor plate contact in the elaboration of contralateral commissural projections within the embryonic mouse spinal cord.	SLIT2 NTN1	3.30e-04	18	52	2	16854408
Pubmed	Amplification of extracellular matrix and oncogenes in tat-transfected human salivary gland cell lines with expression of laminin, fibronectin, collagens I, III, IV, c-myc and p53.	LAMB4 LAMB3	3.30e-04	18	52	2	11311202
Pubmed	Midline radial glia translocation and corpus callosum formation require FGF signaling.	SLIT2 NTN1	3.30e-04	18	52	2	16715082
Pubmed	ATRX proximal protein associations boast roles beyond histone deposition.	ZNF536 ZNF281 NSD3	3.49e-04	91	52	3	34780483
Pubmed	Non-cell autonomous control of precerebellar neuron migration by Slit and Robo proteins.	SLIT2 NTN1	3.69e-04	19	52	2	29343636
Pubmed	Ezh2 orchestrates topographic migration and connectivity of mouse precerebellar neurons.	SLIT2 NTN1	3.69e-04	19	52	2	23307742
Pubmed	Neural RNA-binding protein Musashi1 controls midline crossing of precerebellar neurons through posttranscriptional regulation of Robo3/Rig-1 expression.	SLIT2 NTN1	4.09e-04	20	52	2	20696379
Pubmed	Genetic dissection of the function of hindbrain axonal commissures.	SLIT2 NTN1	4.09e-04	20	52	2	20231872
Pubmed	Global genetic analysis in mice unveils central role for cilia in congenital heart disease.	SLIT2 FRAS1 ZNF366	4.60e-04	100	52	3	25807483
Pubmed	Fras1, a basement membrane-associated protein mutated in Fraser syndrome, mediates both the initiation of the mammalian kidney and the integrity of renal glomeruli.	FRAS1 GDF11	5.44e-04	23	52	2	18787044
Pubmed	Radial glia fibers translate Fgf8 morphogenetic signals to generate a thalamic nuclear complex protomap in the mantle layer.	SLIT2 NTN1	5.44e-04	23	52	2	30470893
Pubmed	Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.	ZBTB48 GAS2L3 ZNF335 ZNF362 TRIM24 NSD3	5.55e-04	689	52	6	36543142
Pubmed	TWIST1 and chromatin regulatory proteins interact to guide neural crest cell differentiation.	TCF20 ZFX NSD3	5.92e-04	109	52	3	33554859
Pubmed	Ca2+ homeostasis maintained by TMCO1 underlies corpus callosum development via ERK signaling.	SLIT2 NTN1	6.96e-04	26	52	2	35927240
Pubmed	Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.	TCF20 ZNF362 TRIM24 ZNF281	6.98e-04	268	52	4	33640491
Pubmed	BMP receptor 1b is required for axon guidance and cell survival in the developing retina.	SLIT2 NTN1	7.51e-04	27	52	2	12654290
Pubmed	Genetic link between renal birth defects and congenital heart disease.	SLIT2 FRAS1	8.08e-04	28	52	2	27002738
Pubmed	The tumor suppressor Nf2 regulates corpus callosum development by inhibiting the transcriptional coactivator Yap.	SLIT2 NTN1	8.67e-04	29	52	2	25336744
Pubmed	Basement membrane assembly of the integrin α8β1 ligand nephronectin requires Fraser syndrome-associated proteins.	FRAS1 LAMB3	8.67e-04	29	52	2	22613833
Pubmed	A Tgfbr1/Snai1-dependent developmental module at the core of vertebrate axial elongation.	GDF11 LIN28A	9.29e-04	30	52	2	32597756
Pubmed	Integration of repulsive guidance cues generates avascular zones that shape mammalian blood vessels.	SLIT2 NTN1	9.92e-04	31	52	2	22076636
Pubmed	Functional analysis of secreted and transmembrane proteins critical to mouse development.	MBTPS1 NTN1	9.92e-04	31	52	2	11431694
Pubmed	BioID identifies novel c-MYC interacting partners in cultured cells and xenograft tumors.	ZC3H14 TCF20 TRIM24	1.08e-03	134	52	3	25452129
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	ZC3H14 TCF20 ZBTB40 ZNF362 TRIM24 ZNF281 IKZF5	1.22e-03	1103	52	7	34189442
Interaction	NOTCH2 interactions	SLIT2 ZNF444 ZNF320 ZNF672 ZNF497 ZBTB48 ZNF253 ZNF335 NTN1 ZNF362	1.07e-07	423	52	10	int:NOTCH2
Interaction	FBLN5 interactions	ZNF444 ZNF320 ZNF764 ZNF253 ZBTB40 GDF11	3.31e-06	159	52	6	int:FBLN5
Interaction	ZSCAN32 interactions	ZNF444 TRAF2 ZSCAN22 ZNF213	5.43e-06	45	52	4	int:ZSCAN32
Interaction	DVL3 interactions	ZNF444 TRAF2 ZNF497 ZBTB48 ZSCAN22 ZNF764 ZNF441	7.27e-06	280	52	7	int:DVL3
Interaction	C1QTNF7 interactions	SLIT2 PDIA5 NTN1 GDF11	3.01e-05	69	52	4	int:C1QTNF7
Interaction	SCAND1 interactions	ZNF449 ZNF444 ZSCAN22 ZNF213	3.19e-05	70	52	4	int:SCAND1
Interaction	FBXO38 interactions	ZNF536 ZBTB40 ZNF362 TRIM24 ZNF281	3.56e-05	145	52	5	int:FBXO38
Interaction	ASF1A interactions	ZNF536 TCF20 ZNF362 TRIM24 ZNF281 NSD3	4.24e-05	249	52	6	int:ASF1A
Interaction	PGBD1 interactions	TRAF2 ZSCAN22 ZNF213	5.65e-05	29	52	3	int:PGBD1
Interaction	APEX1 interactions	SLIT2 ZC3H14 ZNF536 TRAF2 TCF20 ZBTB48 ZNF205 ZNF362 ZNF236 TRIM24 ZNF281 NSD3	7.35e-05	1271	52	12	int:APEX1
Interaction	TERF2IP interactions	ZC3H14 ZNF444 ZNF536 TCF20 ZNF362 TRIM24 ZNF281 NSD3	7.84e-05	552	52	8	int:TERF2IP
Interaction	ZSCAN22 interactions	ZNF449 ZNF444 ZSCAN22	9.16e-05	34	52	3	int:ZSCAN22
Interaction	KRTAP10-7 interactions	ZNF444 ZNF320 ZBTB48 ZNF764 ZNF575 PDIA5	1.04e-04	293	52	6	int:KRTAP10-7
Interaction	CLEC11A interactions	MBTPS1 TRAF2 TCF20 LAMB3	1.10e-04	96	52	4	int:CLEC11A
Interaction	MDFI interactions	ZNF497 ZNF764 ZNF575 LAMB3 PDIA5 ZNF205 ZNF441	1.12e-04	430	52	7	int:MDFI
Interaction	TNFRSF14 interactions	MBTPS1 TRAF2 ZBTB48	1.39e-04	39	52	3	int:TNFRSF14
Interaction	ZNF330 interactions	ZNF536 TCF20 ZNF764 ZNF362 TRIM24 ZNF281 NSD3	1.40e-04	446	52	7	int:ZNF330
Interaction	TBXT interactions	ZNF536 TCF20 TRIM24 ZNF281	2.28e-04	116	52	4	int:TBXT
Interaction	PRG3 interactions	SLIT2 FRAS1 LAMB3	2.75e-04	49	52	3	int:PRG3
Interaction	ZNF449 interactions	ZNF449 ZSCAN22	3.54e-04	11	52	2	int:ZNF449
Interaction	GGH interactions	MBTPS1 FRAS1 LAMB3 PDIA5 TRIM24	4.01e-04	243	52	5	int:GGH
Interaction	ZNF672 interactions	ZNF672 LIN28A	4.24e-04	12	52	2	int:ZNF672
Interaction	SPINK1 interactions	TMPRSS15 PDIA5	4.24e-04	12	52	2	int:SPINK1
Interaction	MLKL interactions	TRAF2 TRIM24 ZNF281	4.30e-04	57	52	3	int:MLKL
Cytoband	19q13.43	ZNF444 ZNF497 ZSCAN22	1.36e-04	87	52	3	19q13.43
Cytoband	16q24	MBTPS1 ZNF469	1.69e-04	17	52	2	16q24
Cytoband	Ensembl 112 genes in cytogenetic band chr19q13	ZNF444 ZNF320 FCGBP ZNF497 ZSCAN22 ZNF575	2.22e-03	1192	52	6	chr19q13
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF449 ZBTB37 ZNF444 ZNF536 ZNF469 ZNF320 ZNF672 ZNF497 ZNF33A ZBTB48 ZSCAN22 ZNF366 ZNF764 ZNF253 ZNF596 ZNF335 ZNF575 ZBTB40 ZNF205 ZNF213 ZNF362 ZNF236 ZNF281 ZNF879 ZNF441 ZFX IKZF5	1.34e-27	718	43	27	28
GeneFamily	Laminin subunits	LAMB4 LAMB3	3.59e-04	12	43	2	626
GeneFamily	Zinc fingers CCCH-type	ZC3H14 MBNL3	3.13e-03	35	43	2	73
GeneFamily	Basic leucine zipper proteins\|BTB domain containing	ZBTB37 ZBTB48 ZBTB40	3.96e-03	134	43	3	861
GeneFamily	PHD finger proteins	TRIM24 NSD3	1.94e-02	90	43	2	88
Coexpression	NABA_ECM_GLYCOPROTEINS	SLIT2 LAMB4 FRAS1 THBS2 LAMB3 NTN1	2.48e-06	196	52	6	M3008
Coexpression	NABA_CORE_MATRISOME	SLIT2 LAMB4 FRAS1 THBS2 LAMB3 NTN1	1.72e-05	275	52	6	M5884
Coexpression	NABA_ECM_GLYCOPROTEINS	SLIT2 FRAS1 THBS2 LAMB3 NTN1	3.84e-05	191	52	5	MM17059
Coexpression	PYEON_CANCER_HEAD_AND_NECK_VS_CERVICAL_UP	GAS2L3 ZNF236 GEN1 ZFX NSD3	4.24e-05	195	52	5	M13736
Coexpression	NABA_BASEMENT_MEMBRANES	LAMB4 LAMB3 NTN1	6.91e-05	40	52	3	M5887
ToppCell	Bronchial-NucSeq-Epithelial-Epi_airway_neuro-secretory-Ionocyte_n_Brush\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	TRAF2 ZNF497 ZNF335 NTN1 ZNF879 CRIP2	1.16e-07	198	52	6	dd0465b45b02cb8edf0914d19afb52fcaaeb012c
Drug	Digitoxigenin [143-62-4]; Up 200; 10.6uM; MCF7; HT_HG-U133A	ZNF764 ZNF335 ZBTB40 ZNF281 ZFX IKZF5	2.19e-06	167	52	6	4801_UP
Drug	Heptaminol hydrochloride [543-15-7]; Down 200; 22uM; HL60; HT_HG-U133A	ZNF444 ZNF536 ZNF253 GDF11 ZFX NSD3	5.36e-06	195	52	6	1866_DN
Drug	vinylene	ZNF536 ZNF33A ZNF335 ZNF213 TRIM24 ZFX	1.96e-05	245	52	6	CID000006326
Drug	Digoxigenin [1672-46-4]; Up 200; 10.2uM; MCF7; HT_HG-U133A	ZNF764 ZNF335 ZBTB40 ZNF281 ZFX	3.20e-05	160	52	5	5275_UP
Drug	Proscillaridin A [466-06-8]; Up 200; 7.6uM; MCF7; HT_HG-U133A	ZNF335 ZBTB40 ZNF236 ZNF281 ZFX	3.40e-05	162	52	5	7340_UP
Drug	Lanatoside C [17575-22-3]; Up 200; 4uM; MCF7; HT_HG-U133A	ZNF764 ZNF335 ZBTB40 ZNF281 ZFX	3.61e-05	164	52	5	3963_UP
Drug	Digoxin [20830-75-5]; Up 200; 5.2uM; MCF7; HT_HG-U133A	ZNF764 ZNF335 ZBTB40 IKZF5 NSD3	3.82e-05	166	52	5	5324_UP
Drug	Strophantine octahydrate [11018-89-6]; Up 200; 5.4uM; PC3; HT_HG-U133A	ZNF764 ZNF335 ZBTB40 ZFX IKZF5	3.93e-05	167	52	5	6680_UP
Disease	Tourette syndrome, schizophrenia	ZNF536 TCF20 NSD3	3.45e-06	18	49	3	EFO_0004895, MONDO_0005090
Disease	hippocampal CA3 volume	SLIT2 NTN1	1.64e-03	36	49	2	EFO_0009395
Disease	Developmental delay (disorder)	TCF20 ZNF335	1.73e-03	37	49	2	C0424605
Disease	hippocampal CA1 volume	SLIT2 NTN1	2.90e-03	48	49	2	EFO_0009394
Disease	glucose metabolism measurement, age-related hearing impairment	ZNF469 UBE2F	3.40e-03	52	49	2	EFO_0005782, EFO_0009367
Disease	Intellectual Disability	ZC3H14 TCF20 ZNF335 ZBTB40	6.43e-03	447	49	4	C3714756

Protein segments in the cluster

Peptide	Gene	Start	Entry
KVCPCFGEKVVHHDP	ARSL	496	P51690
CHLCNASDPKKAHPP	NTN1	91	O95631
FADHAKHKCTACPQG	FRAS1	1041	Q86XX4
EKKSFEKAPCPGCSH	MBTPS1	26	Q14703
HLGIPEPCKADHFQC	TMPRSS15	636	P98073
GEKPHRCHLCPFASA	IKZF5	106	Q9H5V7
TCHAHVPPESFFKGC	FCGBP	1891	Q9Y6R7
AVKHIAEDPPCSCSH	GAS2L3	216	Q86XJ1
DGSPLCCHFHFSPKV	GDF11	156	O95390
ADADCKFAHPPRVCH	MBNL3	31	Q9NUK0
KKLAHCSVCSHPGSP	GEN1	256	Q17RS7
FCHGHADRCAPKPGA	LAMB3	251	Q13751
KLHDGAVACKCHPQG	LAMB4	761	A4D0S4
EHDGKPFCHKPCYAT	CRIP2	46	P52943
CPHCKKVIPHFTATA	PDIA5	426	Q14554
TCKVHFPDPNKLHCF	UBE2F	51	Q969M7
PSHAFAPCGHVCSEK	PELI3	411	Q8N2H9
ACSPKATPKGHHCPV	SPATA31E1	1376	Q6ZUB1
CGADVKAHHEVCPKF	TRAF2	171	Q12933
KAHHEVCPKFPLTCD	TRAF2	176	Q12933
THTGEKPFQCHLCGK	ZBTB48	486	P10074
CEKCPKVFHLSCHVP	TRIM24	841	O15164
HSGEKPHACPECGKA	ZNF444	201	Q8N0Y2
HSSEKPFPCAECGKA	ZNF497	296	Q6ZNH5
VHTGEKPHACAQCGK	ZNF497	351	Q6ZNH5
KECGKPFHCPSAFHK	ZNF441	646	Q8N8Z8
HKCGDCGKAFNSPSH	ZNF320	441	A2RRD8
KPHGCHLCGKAFTHC	ZNF596	221	Q8TC21
KPHGCHLCGKAFTES	ZNF596	361	Q8TC21
RKHTGNKPFHCHVCG	ZBTB37	421	Q5TC79
NKPFHCHVCGKSFPF	ZBTB37	426	Q5TC79
HAGHKPHKCPECSKA	ZNF672	361	Q499Z4
CPHCPKSFGHRSKLA	ZNF575	121	Q86XF7
HCPKAFSFPSKLAAH	ZNF575	181	Q86XF7
PSQKPHICDHCSAAF	ZNF281	256	Q9Y2X9
PGCEPCHKKVCAHGT	SLIT2	1331	O94813
KSGDHCHPPSIKHES	TCF20	946	Q9UGU0
CPHSFCKDHEKGALV	NSD3	1381	Q9BZ95
DPSRDCHHCGKRFPK	ZNF469	3306	Q96JG9
PFACPECGKFFSHKS	ZNF33A	551	Q06730
THTGEKPFKCPYCDH	ZNF536	151	O15090
VVHTGAKPHECKECG	ZSCAN22	316	P10073
CEECGKAFKHPSHVT	ZNF253	286	O75346
GAKPHKCPICAKCFT	ZNF205	416	O95201
SGIKPHACTHCGKLF	ZNF366	276	Q8N895
HTGEKPFHCNECGKV	ZNF879	366	B4DU55
PHKCDMCDKGFHRPS	ZFX	661	P17010
QRTHTGEKPHKCPEC	ZNF213	336	O14771
EAKPHKCPHCSKSFA	ZNF362	251	Q5T0B9
KHTGEKPHACAFCPA	ZNF236	246	Q9UL36
FACPHCDKKFRTSGH	ZNF236	566	Q9UL36
CEPENPCKDKTHNCH	THBS2	646	P35442
SHKRAHAGPGAFKCP	ZNF335	1036	Q9H4Z2
HHPISPCKAFPNCKF	ZC3H14	616	Q6PJT7
GEKPHRCHNCGKSFS	ZNF449	431	Q6P9G9
EVHSKEYHPCPTCGK	ZBTB40	971	Q9NUA8
SHTGEKPFHCTDCGK	ZNF764	196	Q96H86
NCGGLDHHAKECKLP	LIN28A	141	Q9H9Z2