Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	neuron recognition	CNTN4 SEMA5A PLXND1 EFNB3 EPHA4	8.49e-06	59	97	5	GO:0008038
GeneOntologyBiologicalProcess	cellular response to phenylpropanoid	UGT3A1 UGT3A2	2.19e-05	2	97	2	GO:1905546
GeneOntologyBiologicalProcess	cellular response to hydroxyisoflavone	UGT3A1 UGT3A2	2.19e-05	2	97	2	GO:0071413
GeneOntologyBiologicalProcess	cellular response to genistein	UGT3A1 UGT3A2	2.19e-05	2	97	2	GO:0071412
GeneOntologyBiologicalProcess	transition between fast and slow fiber	TEAD1 GTF2IRD2B GTF2IRD2	2.79e-05	13	97	3	GO:0014883
GeneOntologyBiologicalProcess	cell recognition	ATP8B3 CNTN4 SEMA5A PLXND1 EFNB3 CD36 EPHA4	4.18e-05	198	97	7	GO:0008037
GeneOntologyBiologicalProcess	action potential	NEDD4L RYR2 KCNA2 P2RX4 CD36 GNA11 GNAQ	4.60e-05	201	97	7	GO:0001508
GeneOntologyBiologicalProcess	response to genistein	UGT3A1 UGT3A2	6.55e-05	3	97	2	GO:0033595
GeneOntologyBiologicalProcess	semaphorin-plexin signaling pathway	SEMA5A PLXND1 SEMA5B PLXNA2	1.05e-04	52	97	4	GO:0071526
GeneOntologyBiologicalProcess	regulation of skeletal muscle adaptation	TEAD1 GTF2IRD2B GTF2IRD2	1.08e-04	20	97	3	GO:0014733
GeneOntologyBiologicalProcess	cellular response to oxygen-containing compound	ACACA RIPK1 PSG9 CAPN1 UGT3A1 ITGA2 TEAD1 TLR6 JAK1 P2RX4 CD36 XRN1 GNA11 UGT3A2 GNAQ KDM6A EPHA4 FOXC2	1.29e-04	1450	97	18	GO:1901701
GeneOntologyBiologicalProcess	detection of visible light	SEMA5A SEMA5B GNA11 GNAQ	1.50e-04	57	97	4	GO:0009584
GeneOntologyBiologicalProcess	detection of external stimulus	SEMA5A ITGA2 ADGRV1 SEMA5B GNA11 GNAQ	1.68e-04	173	97	6	GO:0009581
GeneOntologyBiologicalProcess	detection of abiotic stimulus	SEMA5A ITGA2 ADGRV1 SEMA5B GNA11 GNAQ	1.79e-04	175	97	6	GO:0009582
GeneOntologyBiologicalProcess	cellular response to diacyl bacterial lipopeptide	TLR6 CD36	2.17e-04	5	97	2	GO:0071726
GeneOntologyBiologicalProcess	response to diacyl bacterial lipopeptide	TLR6 CD36	2.17e-04	5	97	2	GO:0071724
GeneOntologyBiologicalProcess	response to hydroxyisoflavone	UGT3A1 UGT3A2	2.17e-04	5	97	2	GO:0033594
GeneOntologyBiologicalProcess	neuron projection fasciculation	CNTN4 SEMA5A EPHA4	3.03e-04	28	97	3	GO:0106030
GeneOntologyBiologicalProcess	axonal fasciculation	CNTN4 SEMA5A EPHA4	3.03e-04	28	97	3	GO:0007413
GeneOntologyBiologicalProcess	response to phenylpropanoid	UGT3A1 UGT3A2	3.24e-04	6	97	2	GO:0080184
GeneOntologyBiologicalProcess	regulation of cell adhesion	PSG9 CAPN1 SEMA5A ITGA2 PLXND1 JAK1 HHLA2 EFNB3 CD36 MDGA1 PLXNA2 EPHA4 FOXC2	3.96e-04	927	97	13	GO:0030155
GeneOntologyBiologicalProcess	axon guidance	CNTN4 NFASC SEMA5A CSF1R EFNB3 SEMA5B EPHA4	3.98e-04	285	97	7	GO:0007411
GeneOntologyBiologicalProcess	neuron projection guidance	CNTN4 NFASC SEMA5A CSF1R EFNB3 SEMA5B EPHA4	4.06e-04	286	97	7	GO:0097485
GeneOntologyBiologicalProcess	regulation of melanocyte differentiation	GNA11 GNAQ	4.53e-04	7	97	2	GO:0045634
GeneOntologyBiologicalProcess	skeletal muscle adaptation	TEAD1 GTF2IRD2B GTF2IRD2	4.53e-04	32	97	3	GO:0043501
GeneOntologyBiologicalProcess	detection of light stimulus	SEMA5A SEMA5B GNA11 GNAQ	4.78e-04	77	97	4	GO:0009583
GeneOntologyCellularComponent	side of membrane	CNTN4 LYPD6B PSG9 ITGA2 LCT RYR2 JAK1 HHLA2 CD36 CNTN3 GNA11 GNAQ MDGA1 ALG6	5.67e-05	875	98	14	GO:0098552
GeneOntologyCellularComponent	UDP-N-acetylglucosamine transferase complex	UGT3A1 UGT3A2	1.30e-04	4	98	2	GO:0043541
GeneOntologyCellularComponent	extrinsic component of cytoplasmic side of plasma membrane	RYR2 JAK1 GNA11 GNAQ	1.38e-04	56	98	4	GO:0031234
Domain	Semap_dom	SEMA5A PLXND1 SEMA5B PLXNA2	1.93e-05	31	97	4	IPR001627
Domain	SEMA	SEMA5A PLXND1 SEMA5B PLXNA2	1.93e-05	31	97	4	PS51004
Domain	Sema	SEMA5A PLXND1 SEMA5B PLXNA2	1.93e-05	31	97	4	SM00630
Domain	Sema	SEMA5A PLXND1 SEMA5B PLXNA2	1.93e-05	31	97	4	PF01403
Domain	Plexin_repeat	SEMA5A PLXND1 SEMA5B PLXNA2	2.20e-05	32	97	4	IPR002165
Domain	PSI	SEMA5A PLXND1 SEMA5B PLXNA2	2.20e-05	32	97	4	PF01437
Domain	PSI	SEMA5A PLXND1 SEMA5B PLXNA2	7.91e-05	44	97	4	IPR016201
Domain	PSI	SEMA5A PLXND1 SEMA5B PLXNA2	9.44e-05	46	97	4	SM00423
Domain	-	GTF2IRD2B GTF2IRD2	1.59e-04	4	97	2	3.90.1460.10
Domain	Gprotein_alpha_Q	GNA11 GNAQ	1.59e-04	4	97	2	IPR000654
Domain	GTF2I	GTF2IRD2B GTF2IRD2	1.59e-04	4	97	2	PS51139
Domain	GTF2I	GTF2IRD2B GTF2IRD2	1.59e-04	4	97	2	PF02946
Domain	GTF2I	GTF2IRD2B GTF2IRD2	1.59e-04	4	97	2	IPR004212
Domain	ig	CNTN4 PSG9 NFASC CSF1R CNTN3 MDGA1	4.70e-04	190	97	6	PF00047
Domain	Immunoglobulin	CNTN4 PSG9 NFASC CSF1R CNTN3 MDGA1	4.70e-04	190	97	6	IPR013151
Domain	C2	RPGRIP1 NEDD4L WWP1 MCTP1 PIK3C2G	6.05e-04	131	97	5	PF00168
Domain	EF-hand_8	CAPN1 RYR2 CAPN11	7.23e-04	34	97	3	PF13833
Domain	C2	RPGRIP1 NEDD4L WWP1 MCTP1 PIK3C2G	7.41e-04	137	97	5	SM00239
Domain	C2	RPGRIP1 NEDD4L WWP1 MCTP1 PIK3C2G	8.71e-04	142	97	5	PS50004
Domain	Plexin_cytopl	PLXND1 PLXNA2	9.39e-04	9	97	2	PF08337
Domain	Plexin_cytoplasmic_RasGAP_dom	PLXND1 PLXNA2	9.39e-04	9	97	2	IPR013548
Domain	Plexin	PLXND1 PLXNA2	9.39e-04	9	97	2	IPR031148
Domain	-	RPGRIP1 NEDD4L WWP1 MCTP1 PIK3C2G	1.05e-03	148	97	5	2.60.40.150
Domain	Ig-like_fold	CNTN4 PSG9 NFASC PLXND1 HHLA2 CSF1R IGKC CNTN3 MDGA1 PLXNA2 EPHA4	1.08e-03	706	97	11	IPR013783
Domain	IGc2	CNTN4 PSG9 NFASC CSF1R CNTN3 MDGA1	1.42e-03	235	97	6	SM00408
Domain	Ig_sub2	CNTN4 PSG9 NFASC CSF1R CNTN3 MDGA1	1.42e-03	235	97	6	IPR003598
Domain	C2_dom	RPGRIP1 NEDD4L WWP1 MCTP1 PIK3C2G	1.65e-03	164	97	5	IPR000008
Domain	calpain_III	CAPN1 CAPN11	1.70e-03	12	97	2	SM00720
Domain	C2_III	CAPN1 CAPN11	1.70e-03	12	97	2	IPR033883
Domain	WWE	PARP11 PARP12	1.70e-03	12	97	2	PF02825
Domain	WWE-dom	PARP11 PARP12	1.70e-03	12	97	2	IPR004170
Domain	WWE	PARP11 PARP12	1.70e-03	12	97	2	PS50918
Domain	Calpain_III	CAPN1 CAPN11	1.70e-03	12	97	2	IPR022683
Domain	-	SEMA5A PLXND1 LYST SCAP SEMA5B UTP15 PLXNA2	1.75e-03	333	97	7	2.130.10.10
Domain	WD40/YVTN_repeat-like_dom	SEMA5A PLXND1 LYST SCAP SEMA5B UTP15 PLXNA2	1.81e-03	335	97	7	IPR015943
Domain	Calpain_III	CAPN1 CAPN11	2.01e-03	13	97	2	PF01067
Domain	Calpain_domain_III	CAPN1 CAPN11	2.01e-03	13	97	2	IPR022682
Domain	-	CNTN4 PSG9 NFASC PLXND1 HHLA2 CSF1R CNTN3 MDGA1 PLXNA2 EPHA4	2.32e-03	663	97	10	2.60.40.10
Domain	Calpain_cysteine_protease	CAPN1 CAPN11	2.33e-03	14	97	2	IPR022684
Domain	Peptidase_C2	CAPN1 CAPN11	2.68e-03	15	97	2	PF00648
Domain	CysPc	CAPN1 CAPN11	2.68e-03	15	97	2	SM00230
Domain	Peptidase_C2_calpain_cat	CAPN1 CAPN11	2.68e-03	15	97	2	IPR001300
Domain	CALPAIN_CAT	CAPN1 CAPN11	2.68e-03	15	97	2	PS50203
Domain	FN3	CNTN4 NFASC CNTN3 MDGA1 EPHA4	2.79e-03	185	97	5	SM00060
Domain	GproteinA_insert	GNA11 GNAQ	3.06e-03	16	97	2	IPR011025
Domain	-	GNA11 GNAQ	3.06e-03	16	97	2	1.10.400.10
Domain	G-alpha	GNA11 GNAQ	3.06e-03	16	97	2	PF00503
Domain	G_alpha	GNA11 GNAQ	3.06e-03	16	97	2	SM00275
Domain	Poly(ADP-ribose)pol_cat_dom	PARP11 PARP12	3.45e-03	17	97	2	IPR012317
Domain	PARP_CATALYTIC	PARP11 PARP12	3.45e-03	17	97	2	PS51059
Domain	PARP	PARP11 PARP12	3.45e-03	17	97	2	PF00644
Domain	Gprotein_alpha_su	GNA11 GNAQ	3.45e-03	17	97	2	IPR001019
Domain	-	PARP11 PARP12	3.45e-03	17	97	2	3.90.228.10
Domain	FN3	CNTN4 NFASC CNTN3 MDGA1 EPHA4	3.81e-03	199	97	5	PS50853
Domain	IG_LIKE	CNTN4 PSG9 NFASC HHLA2 CSF1R IGKC CNTN3 MDGA1	4.04e-03	491	97	8	PS50835
Domain	Pkinase_Tyr	RIPK1 JAK1 CSF1R EPHA4	4.59e-03	129	97	4	PF07714
Domain	Ig-like_dom	CNTN4 PSG9 NFASC HHLA2 CSF1R IGKC CNTN3 MDGA1	4.66e-03	503	97	8	IPR007110
Domain	FN3_dom	CNTN4 NFASC CNTN3 MDGA1 EPHA4	4.69e-03	209	97	5	IPR003961
Domain	Semaphorin	SEMA5A SEMA5B	4.77e-03	20	97	2	IPR027231
Pathway	REACTOME_FREE_FATTY_ACIDS_REGULATE_INSULIN_SECRETION	CD36 GNA11 GNAQ	2.13e-05	11	73	3	M27317
Pathway	REACTOME_FREE_FATTY_ACIDS_REGULATE_INSULIN_SECRETION	CD36 GNA11 GNAQ	2.13e-05	11	73	3	MM15035
Pathway	REACTOME_OTHER_SEMAPHORIN_INTERACTIONS	SEMA5A PLXND1 PLXNA2	1.22e-04	19	73	3	M10959
Pathway	REACTOME_REGULATION_OF_TLR_BY_ENDOGENOUS_LIGAND	APOB TLR6 CD36	1.91e-04	22	73	3	M27571
Pathway	REACTOME_REGULATION_OF_TLR_BY_ENDOGENOUS_LIGAND	APOB TLR6 CD36	1.91e-04	22	73	3	MM15284
Pathway	REACTOME_ION_CHANNEL_TRANSPORT	ATP8B3 NEDD4L RIPK1 WWP1 ATP13A5 RYR2	2.96e-04	176	73	6	MM15718
Pathway	REACTOME_ION_CHANNEL_TRANSPORT	ATP8B3 NEDD4L RIPK1 WWP1 ATP13A5 RYR2	3.65e-04	183	73	6	M997
Pathway	REACTOME_SCAVENGING_BY_CLASS_B_RECEPTORS	APOB CD36	3.91e-04	6	73	2	M27220
Pathway	KEGG_MEDICUS_PATHOGEN_HCMV_UL33_TO_GNAQ_PLCB_G_CALCINEURIN_SIGNALING_PATHWAY	GNA11 GNAQ	3.91e-04	6	73	2	M47548
Pubmed	An extracellular biochemical screen reveals that FLRTs and Unc5s mediate neuronal subtype recognition in the retina.	CNTN4 SEMA5A PLXND1 SEMA5B CNTN3 PLXNA2	8.36e-09	52	99	6	26633812
Pubmed	Diabetes-related defects in sarcoplasmic Ca2+ release are prevented by inactivation of G(alpha)11 and G(alpha)q in murine cardiomyocytes.	RYR2 GNA11 GNAQ	2.24e-08	3	99	3	20372981
Pubmed	Semaphorin 5A inhibits synaptogenesis in early postnatal- and adult-born hippocampal dentate granule cells.	SEMA5A SEMA5B PLXNA2	2.23e-07	5	99	3	25313870
Pubmed	TrkB-dependent EphrinA reverse signaling regulates callosal axon fasciculate growth downstream of Neurod2/6.	SEMA5A PLXND1 EFNB3 SEMA5B PLXNA2	2.35e-07	47	99	5	35462405
Pubmed	Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.	CNTN4 APOB PLXND1 CSF1R SERPING1 CNTN3 MDGA1 SERPINA7	7.64e-07	257	99	8	16335952
Pubmed	Semaphorin heterodimerization in cis regulates membrane targeting and neocortical wiring.	SEMA5A PLXND1 EFNB3 PLXNA2	8.80e-07	26	99	4	39152101
Pubmed	PlexinA1 signaling directs the segregation of proprioceptive sensory axons in the developing spinal cord.	SEMA5A PLXND1 SEMA5B MDGA1 PLXNA2 EPHA4	1.11e-06	117	99	6	17145500
Pubmed	A role for Nr-CAM in the patterning of binocular visual pathways.	CNTN4 NFASC CNTN3	4.83e-06	12	99	3	16701205
Pubmed	A dual-strategy expression screen for candidate connectivity labels in the developing thalamus.	EFNB3 TENM1 MDGA1 PLXNA2 EPHA4	6.47e-06	91	99	5	28558017
Pubmed	EphA4 (Sek1) receptor tyrosine kinase is required for the development of the corticospinal tract.	EFNB3 EPHA4	8.02e-06	2	99	2	9789074
Pubmed	The Role of Mutation Rates of GNAQ or GNA11 in Cases of Uveal Melanoma in Japan.	GNA11 GNAQ	8.02e-06	2	99	2	28248732
Pubmed	Activation of Gq/11 in the mouse corpus luteum is required for parturition.	GNA11 GNAQ	8.02e-06	2	99	2	25495873
Pubmed	CD36 binds oxidized low density lipoprotein (LDL) in a mechanism dependent upon fatty acid binding.	APOB CD36	8.02e-06	2	99	2	25555908
Pubmed	Forward signaling mediated by ephrin-B3 prevents contralateral corticospinal axons from recrossing the spinal cord midline.	EFNB3 EPHA4	8.02e-06	2	99	2	11182083
Pubmed	Identification of residues that confer sugar selectivity to UDP-glycosyltransferase 3A (UGT3A) enzymes.	UGT3A1 UGT3A2	8.02e-06	2	99	2	22621930
Pubmed	Molecular genetic testing of uveal melanoma from routinely processed and stained cytology specimens.	GNA11 GNAQ	8.02e-06	2	99	2	21945171
Pubmed	Interaction of the G-protein G11alpha with receptors and phosphoinositidase C: the contribution of G-protein palmitoylation and membrane association.	GNA11 GNAQ	8.02e-06	2	99	2	9175863
Pubmed	The ethnic profile of patients with birthmarks reveals interaction of germline and postzygotic genetics.	GNA11 GNAQ	8.02e-06	2	99	2	28083870
Pubmed	Development and reorganization of corticospinal projections in EphA4 deficient mice.	EFNB3 EPHA4	8.02e-06	2	99	2	11438928
Pubmed	Gq/11-Dependent Changes in the Murine Ovarian Transcriptome at the End of Gestation.	GNA11 GNAQ	8.02e-06	2	99	2	26843449
Pubmed	Direct targeting of Gαq and Gα11 oncoproteins in cancer cells.	GNA11 GNAQ	8.02e-06	2	99	2	30890659
Pubmed	Gonadotropin and gonadal steroid release in response to a gonadotropin-releasing hormone agonist in Gqalpha and G11alpha knockout mice.	GNA11 GNAQ	8.02e-06	2	99	2	9607776
Pubmed	Reverse Phenotyping in Patients with Skin Capillary Malformations and Mosaic GNAQ or GNA11 Mutations Defines a Clinical Spectrum with Genotype-Phenotype Correlation.	GNA11 GNAQ	8.02e-06	2	99	2	31726051
Pubmed	G(alpha)q-deficient mice lack metabotropic glutamate receptor-dependent long-term depression but show normal long-term potentiation in the hippocampal CA1 region.	GNA11 GNAQ	8.02e-06	2	99	2	11438569
Pubmed	GNAQ/GNA11 Mosaicism Is Associated with Abnormal Serum Calcium Indices and Microvascular Neurocalcification.	GNA11 GNAQ	8.02e-06	2	99	2	37802294
Pubmed	Distinct profiles of functional discrimination among G proteins determine the actions of G protein-coupled receptors.	GNA11 GNAQ	8.02e-06	2	99	2	26628681
Pubmed	The time-course of agonist-induced solubilization of trimeric G(q)alpha/G(11)alpha proteins resolved by two-dimensional electrophoresis.	GNA11 GNAQ	8.02e-06	2	99	2	17552882
Pubmed	Heterogeneity in Mitogen-Activated Protein Kinase (MAPK) Pathway Activation in Uveal Melanoma With Somatic GNAQ and GNA11 Mutations.	GNA11 GNAQ	8.02e-06	2	99	2	31173078
Pubmed	Frequent and Yet Unreported GNAQ and GNA11 Mutations are Found in Uveal Melanomas.	GNA11 GNAQ	8.02e-06	2	99	2	29209985
Pubmed	EphrinB3 is an anti-apoptotic ligand that inhibits the dependence receptor functions of EphA4 receptors during adult neurogenesis.	EFNB3 EPHA4	8.02e-06	2	99	2	18948148
Pubmed	Distinct roles of Galpha(q) and Galpha11 for Purkinje cell signaling and motor behavior.	GNA11 GNAQ	8.02e-06	2	99	2	15175381
Pubmed	Oncogenic GNAQ and GNA11 mutations in uveal melanoma in Chinese.	GNA11 GNAQ	8.02e-06	2	99	2	25280020
Pubmed	GNAQ and GNA11 mutations occur in 9.5% of mucosal melanoma and are associated with poor prognosis.	GNA11 GNAQ	8.02e-06	2	99	2	27498141
Pubmed	Structure and function of Semaphorin-5A glycosaminoglycan interactions.	SEMA5A PLXNA2	8.02e-06	2	99	2	38548715
Pubmed	Uveal Melanoma: GNAQ and GNA11 Mutations in a Greek Population.	GNA11 GNAQ	8.02e-06	2	99	2	28982892
Pubmed	Mutations in GNA11 in uveal melanoma.	GNA11 GNAQ	8.02e-06	2	99	2	21083380
Pubmed	GNAQ and GNA11 mutations in uveal melanoma.	GNA11 GNAQ	8.02e-06	2	99	2	25304237
Pubmed	Epidermal loss of Gαq confers a migratory and differentiation defect in keratinocytes.	GNA11 GNAQ	8.02e-06	2	99	2	28301547
Pubmed	Forebrain-specific inactivation of Gq/G11 family G proteins results in age-dependent epilepsy and impaired endocannabinoid formation.	GNA11 GNAQ	8.02e-06	2	99	2	16847339
Pubmed	Uveal melanoma driver mutations in GNAQ/11 yield numerous changes in melanocyte biology.	GNA11 GNAQ	8.02e-06	2	99	2	29570931
Pubmed	Muscarinic inhibition of calcium current and M current in Galpha q-deficient mice.	GNA11 GNAQ	8.02e-06	2	99	2	10818132
Pubmed	Endothelial Gαq/11 is required for VEGF-induced vascular permeability and angiogenesis.	GNA11 GNAQ	8.02e-06	2	99	2	26272756
Pubmed	NK2 receptor-mediated detrusor muscle contraction involves Gq/11-dependent activation of voltage-dependent Ca2+ channels and the RhoA-Rho kinase pathway.	GNA11 GNAQ	8.02e-06	2	99	2	31461351
Pubmed	Ultradeep sequencing detects GNAQ and GNA11 mutations in cell-free DNA from plasma of patients with uveal melanoma.	GNA11 GNAQ	8.02e-06	2	99	2	23634288
Pubmed	Distribution of GNAQ and GNA11 Mutation Signatures in Uveal Melanoma Points to a Light Dependent Mutation Mechanism.	GNA11 GNAQ	8.02e-06	2	99	2	26368812
Pubmed	Postsynaptic mechanisms underlying responsiveness of amygdaloid neurons to cholecystokinin are mediated by a transient receptor potential-like current.	GNA11 GNAQ	8.02e-06	2	99	2	17482476
Pubmed	Combined PKC and MEK inhibition in uveal melanoma with GNAQ and GNA11 mutations.	GNA11 GNAQ	8.02e-06	2	99	2	24141786
Pubmed	Ephrin-B3-EphA4 interactions regulate the growth of specific thalamocortical axon populations in vitro.	EFNB3 EPHA4	8.02e-06	2	99	2	12383247
Pubmed	Stretch regulates alveologenesis and homeostasis via mesenchymal Gαq/11-mediated TGFβ2 activation.	GNA11 GNAQ	8.02e-06	2	99	2	37102682
Pubmed	Ca2+ signalling in K562 human erythroleukaemia cells: effect of dimethyl sulphoxide and role of G-proteins in thrombin- and thromboxane A2-activated pathways.	GNA11 GNAQ	8.02e-06	2	99	2	7492305
Pubmed	Reduced trabecular bone mass and strength in mice overexpressing Gα11 protein in cells of the osteoblast lineage.	GNA11 GNAQ	8.02e-06	2	99	2	24308950
Pubmed	Gαq and Gα11 contribute to the maintenance of cellular electrophysiology and Ca2+ handling in ventricular cardiomyocytes.	GNA11 GNAQ	8.02e-06	2	99	2	22562663
Pubmed	Functional specificity of G alpha q and G alpha 11 in the cholinergic and glutamatergic modulation of potassium currents and excitability in hippocampal neurons.	GNA11 GNAQ	8.02e-06	2	99	2	11826096
Pubmed	Blue nevi and variants: an update.	GNA11 GNAQ	8.02e-06	2	99	2	21366456
Pubmed	In uveal melanoma Gα-protein GNA11 mutations convey a shorter disease-specific survival and are more strongly associated with loss of BAP1 and chromosomal alterations than Gα-protein GNAQ mutations.	GNA11 GNAQ	8.02e-06	2	99	2	35580369
Pubmed	Papillary Hemangioma Harbors Somatic GNA11 and GNAQ Mutations.	GNA11 GNAQ	8.02e-06	2	99	2	37750536
Pubmed	Mosaic Activating Mutations in GNA11 and GNAQ Are Associated with Phakomatosis Pigmentovascularis and Extensive Dermal Melanocytosis.	GNA11 GNAQ	8.02e-06	2	99	2	26778290
Pubmed	Skeletal Muscle-Specific Activation of Gq Signaling Maintains Glucose Homeostasis.	GNA11 GNAQ	8.02e-06	2	99	2	30936140
Pubmed	Patient survival in uveal melanoma is not affected by oncogenic mutations in GNAQ and GNA11.	GNA11 GNAQ	8.02e-06	2	99	2	23778528
Pubmed	High throughput mass spectrometry-based mutation profiling of primary uveal melanoma.	GNA11 GNAQ	8.02e-06	2	99	2	22977135
Pubmed	An experimental strategy to probe Gq contribution to signal transduction in living cells.	GNA11 GNAQ	8.02e-06	2	99	2	33639168
Pubmed	GNAQ and GNA11 mutant nonuveal melanoma: a subtype distinct from both cutaneous and uveal melanoma.	GNA11 GNAQ	8.02e-06	2	99	2	32064597
Pubmed	Mutational analysis of GNAQ and GNA11 to aid therapy management of a choroidal melanoma metastatic to the contralateral orbit.	GNA11 GNAQ	8.02e-06	2	99	2	23572068
Pubmed	Low mutational burden of eight genes involved in the MAPK/ERK, PI3K/AKT, and GNAQ/11 pathways in female genital tract primary melanomas.	GNA11 GNAQ	8.02e-06	2	99	2	25695059
Pubmed	Comparison of TFII-I gene family members deleted in Williams-Beuren syndrome.	GTF2IRD2B GTF2IRD2	8.02e-06	2	99	2	15388857
Pubmed	Group I metabotropic glutamate receptor signaling via Galpha q/Galpha 11 secures the induction of long-term potentiation in the hippocampal area CA1.	GNA11 GNAQ	8.02e-06	2	99	2	12351712
Pubmed	Cardiac remodeling in Gαq and Gα11 knockout mice.	GNA11 GNAQ	8.02e-06	2	99	2	26476043
Pubmed	Early-onset hypertension associated with extensive cutaneous capillary malformations harboring postzygotic variants in GNAQ and GNA11.	GNA11 GNAQ	8.02e-06	2	99	2	36440997
Pubmed	Loss of Gq/11 family G proteins in the nervous system causes pituitary somatotroph hypoplasia and dwarfism in mice.	GNA11 GNAQ	8.02e-06	2	99	2	15713647
Pubmed	GNAQ and GNA11 mutations in melanocytomas of the central nervous system.	GNA11 GNAQ	8.02e-06	2	99	2	22307269
Pubmed	In the developing cerebral cortex: axonogenesis, synapse formation, and synaptic plasticity are regulated by SATB2 target genes.	PLXND1 PLXNA2 EPHA4	9.93e-06	15	99	3	36028553
Pubmed	In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.	NEDD4L WWP1 CAPN1 HNRNPM SEMA5A APOB PEF1 P2RX4 IGKC SERPING1 GNA11 GNAQ SERPINA7	1.10e-05	1070	99	13	23533145
Pubmed	Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.	PARP11 COG2 EDC3 ACACA GPX8 HIKESHI INPP5A FBXO11 TEAD1 CCNC SCAP XRN1 COG5 ALG6	2.38e-05	1327	99	14	32694731
Pubmed	Dissecting Gq/11-Mediated Plasma Membrane Translocation of Sphingosine Kinase-1.	GNA11 GNAQ	2.40e-05	3	99	2	33003441
Pubmed	P2Y₂ and Gq/G₁₁ control blood pressure by mediating endothelial mechanotransduction.	GNA11 GNAQ	2.40e-05	3	99	2	26168216
Pubmed	Kinase-dependent and kinase-independent functions of EphA4 receptors in major axon tract formation in vivo.	EFNB3 EPHA4	2.40e-05	3	99	2	11182082
Pubmed	Specificity of G alpha q and G alpha 11 gene expression in platelets and erythrocytes. Expressions of cellular differentiation and species differences.	GNA11 GNAQ	2.40e-05	3	99	2	8836152
Pubmed	TANGO1 and Mia2/cTAGE5 (TALI) cooperate to export bulky pre-chylomicrons/VLDLs from the endoplasmic reticulum.	APOB MIA2	2.40e-05	3	99	2	27138255
Pubmed	The orphan receptor GPR139 signals via Gq/11 to oppose opioid effects.	GNA11 GNAQ	2.40e-05	3	99	2	32576659
Pubmed	Very large G protein-coupled receptor 1 regulates myelin-associated glycoprotein via Gαs/Gαq-mediated protein kinases A/C.	ADGRV1 GNAQ	2.40e-05	3	99	2	24191038
Pubmed	Hippocampal plasticity requires postsynaptic ephrinBs.	EFNB3 EPHA4	2.40e-05	3	99	2	14699416
Pubmed	Thyrocyte-specific Gq/G11 deficiency impairs thyroid function and prevents goiter development.	GNA11 GNAQ	2.40e-05	3	99	2	17694176
Pubmed	Regulation of the epithelial Na+ channel by the RH domain of G protein-coupled receptor kinase, GRK2, and Galphaq/11.	GNA11 GNAQ	2.40e-05	3	99	2	21464134
Pubmed	G protein diversity: a distinct class of alpha subunits is present in vertebrates and invertebrates.	GNA11 GNAQ	2.40e-05	3	99	2	2123549
Pubmed	CXCL2/CXCR2 axis induces cancer stem cell characteristics in CPT-11-resistant LoVo colon cancer cells via Gαi-2 and Gαq/11.	GNA11 GNAQ	2.40e-05	3	99	2	30552676
Pubmed	G alpha(q) signal in osteoblasts is inhibitory to the osteoanabolic action of parathyroid hormone.	GNA11 GNAQ	2.40e-05	3	99	2	21345793
Pubmed	Normal hematopoiesis and inflammatory responses despite discrete signaling defects in Galpha15 knockout mice.	GNA11 GNAQ	2.40e-05	3	99	2	10629036
Pubmed	Intramembrane attenuation of the TLR4-TLR6 dimer impairs receptor assembly and reduces microglia-mediated neurodegeneration.	TLR6 CD36	2.40e-05	3	99	2	28655763
Pubmed	High frequency of GNA14, GNAQ, and GNA11 mutations in cherry hemangioma: a histopathological and molecular study of 85 cases indicating GNA14 as the most commonly mutated gene in vascular neoplasms.	GNA11 GNAQ	2.40e-05	3	99	2	31189994
Pubmed	Heterotrimeric G alpha q/G alpha 11 proteins function upstream of vascular endothelial growth factor (VEGF) receptor-2 (KDR) phosphorylation in vascular permeability factor/VEGF signaling.	GNA11 GNAQ	2.40e-05	3	99	2	12670961
Pubmed	Uterine Gαq/11 signaling, in a progesterone-dependent manner, critically regulates the acquisition of uterine receptivity in the female mouse.	GNA11 GNAQ	2.40e-05	3	99	2	31091422
Pubmed	G(q/11)α and G(s)α mediate distinct physiological responses to central melanocortins.	GNA11 GNAQ	2.40e-05	3	99	2	26595811
Pubmed	Frequent GNAQ, GNA11, and EIF1AX Mutations in Iris Melanoma.	GNA11 GNAQ	2.40e-05	3	99	2	28700778
Pubmed	The prostacyclin receptor is isoprenylated. Isoprenylation is required for efficient receptor-effector coupling.	GNA11 GNAQ	2.40e-05	3	99	2	10446129
Pubmed	Downregulations of CD36 and Calpain-1, Inflammation, and Atherosclerosis by Simvastatin in Apolipoprotein E Knockout Mice.	CAPN1 CD36	2.40e-05	3	99	2	28448973
Pubmed	Gqα/G11α deficiency in dorsomedial hypothalamus leads to obesity resulting from decreased energy expenditure and impaired sympathetic nerve activity.	GNA11 GNAQ	2.40e-05	3	99	2	33166186
Pubmed	Absence of pressure overload induced myocardial hypertrophy after conditional inactivation of Galphaq/Galpha11 in cardiomyocytes.	GNA11 GNAQ	2.40e-05	3	99	2	11689889
Pubmed	Endocannabinoid-mediated modulation of Gq/11 protein-coupled receptor signaling-induced vasoconstriction and hypertension.	GNA11 GNAQ	2.40e-05	3	99	2	25595485
Pubmed	The effects of Eph-ephrin mutations on pre-pulse inhibition in mice.	EFNB3 EPHA4	2.40e-05	3	99	2	24949848
Pubmed	Identification of HRAS mutations and absence of GNAQ or GNA11 mutations in deep penetrating nevi.	GNA11 GNAQ	2.40e-05	3	99	2	23599145
Interaction	SEMA3D interactions	HNRNPM PLXND1 PLXNA2	8.89e-06	9	97	3	int:SEMA3D
GeneFamily	Components of oligomeric golgi complex	COG2 COG5	4.55e-04	8	74	2	493
GeneFamily	Plexins	PLXND1 PLXNA2	5.84e-04	9	74	2	683
GeneFamily	C2 domain containing\|Calpains	CAPN1 CAPN11	1.68e-03	15	74	2	975
GeneFamily	Zinc fingers\|Zinc fingers PARP-type\|Poly(ADP-ribose) polymerases	PARP11 PARP12	2.16e-03	17	74	2	684
GeneFamily	Immunoglobulin like domain containing\|Semaphorins	SEMA5A SEMA5B	2.99e-03	20	74	2	736
GeneFamily	Fibronectin type III domain containing	CNTN4 NFASC CNTN3 EPHA4	4.20e-03	160	74	4	555
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	CNTN4 NFASC CNTN3 MDGA1	4.30e-03	161	74	4	593
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c11-GNLY\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ABCA13 INPP5A ZNF395 TBC1D13 GTF2IRD2B TIGD2	8.15e-07	143	99	6	8f897278f9ccc82ae35e4f30c5f930b2a3eb509d
ToppCell	droplet-Liver-Hepatocytes-24m\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UGT3A1 APOB ZNF395 SERPING1 CNTN3 SERPINA7	8.84e-07	145	99	6	f142b86d4da5b71c189da46cbc4beebdc387ffee
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CNTN4 ATP13A5 ADGRV1 RYR2 PIK3C2G CNTN3	1.57e-06	160	99	6	c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CNTN4 ATP13A5 ADGRV1 RYR2 PIK3C2G CNTN3	1.57e-06	160	99	6	25c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell	facs-Lung-EPCAM-24m-Lymphocytic-lymphocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PARP11 MAN2A2 ACACA ISOC1 TIGD2 PNPLA7	2.47e-06	173	99	6	6e92983d9f8a2a37f23e60a0d5bb1738217897bc
ToppCell	facs-Lung-EPCAM-24m-Lymphocytic-Alox5+_Lymphocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PARP11 MAN2A2 ACACA ISOC1 TIGD2 PNPLA7	2.47e-06	173	99	6	4c788c1dad1da495b3b5c10f95e779848dfe85dc
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SEMA5A TEAD1 MCTP1 PIK3C2G TENM1 PLXNA2	3.11e-06	180	99	6	e8841ef1239f9ee73ac4f4e11faca0742694f368
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LYPD6B WWP1 UGT3A1 ITGA2 MCTP1 PIK3C2G	3.21e-06	181	99	6	aa233b652921848af2257cc3687a7a09c3acfb67
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_VWA2\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SEMA5A TEAD1 MCTP1 SEMA5B TENM1 PLXNA2	3.31e-06	182	99	6	72e65a23cd36085bc880087d3cae92395de918a1
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SEMA5A TEAD1 MCTP1 SEMA5B TENM1 PLXNA2	3.31e-06	182	99	6	05c167158815bf25d509df59ab386e1990712765
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA13 APOB ADGRV1 RYR2 PIK3C2G TENM1	3.52e-06	184	99	6	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA13 APOB ADGRV1 RYR2 PIK3C2G TENM1	3.52e-06	184	99	6	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA13 APOB ADGRV1 RYR2 PIK3C2G TENM1	3.52e-06	184	99	6	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1-D175\|Adult / Lineage, Cell type, age group and donor	CNTN4 OVCH2 NEDD4L SEMA5A ITGA2 TEAD1	3.64e-06	185	99	6	32b4e68e551d435a732f253f6ad83408c759a642
ToppCell	Parenchymal-NucSeq\|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations	NEDD4L ACACA ADGRV1 TEAD1 COG5 KDM6A	5.37e-06	198	99	6	1996373bdccc55aac347d349bd22f6aad6d0c668
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LYPD6B OVCH2 APOB PIK3C2G UGT3A2	1.82e-05	145	99	5	fd02d55755c35288a42ab08a82450b370aad35a7
ToppCell	facs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA13 ATP13A5 ADGRV1 TENM1 CNTN3	1.82e-05	145	99	5	96712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCell	droplet-Heart-nan-24m-Mesenchymal-nan\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CAPN1 DUSP14 ADGRV1 P4HTM SERPING1	2.83e-05	159	99	5	7ad3a91d29639b32f6264c91f401c14a35469ac0
ToppCell	facs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ABCA13 ATP13A5 ADGRV1 TENM1 CNTN3	3.10e-05	162	99	5	bf886e22ff2a20353499004b53f25fb9e6574896
ToppCell	facs-Diaphragm-Limb_Muscle-24m\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA13 ATP13A5 ADGRV1 RYR2 PIK3C2G	3.79e-05	169	99	5	12bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCell	droplet-Kidney-nan-21m-Epithelial-Epcam____brush_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UGT3A1 APOB CSF1R CD36 UGT3A2	4.01e-05	171	99	5	8e7223ba447947cdf4e1c82a52fd90439cf3d8f6
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	LYPD6B PLXND1 MCTP1 CD36 PLXNA2	4.35e-05	174	99	5	3d4c05ea5719ca65e85d1f15198453034791087c
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SEMA5A TEAD1 MCTP1 SEMA5B TENM1	4.60e-05	176	99	5	72a2a01618ce836bc843395d5095e9090759b4a6
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting-Basal_resting_L.0.0.0.3\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NEDD4L CAPN1 LAPTM4B GRID2IP CNTN3	4.72e-05	177	99	5	8c6d8a1c469346e66f9095d86b4615f8fc611362
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SEMA5A MCTP1 SEMA5B TENM1 PNPLA7	4.72e-05	177	99	5	4c069f0d044a96118090b85ca592a21d6b5d9399
ToppCell	Children_(3_yrs)-Epithelial-basal_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CNTN4 NEDD4L ITGA2 CNTN3 PLXNA2	4.85e-05	178	99	5	fba2e38c05cbf031e0c6d47b1602575fea734a57
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SEMA5A ITGA2 HHLA2 EFNB3 PGBD5	4.85e-05	178	99	5	a0ab20c588e7d43d0320d4779d9ab95c1c86e297
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CNTN4 OVCH2 NEDD4L ADGRV1 TEAD1	4.98e-05	179	99	5	cb38b54261a7af5ee3347e64c8aa880a77ed0763
ToppCell	facs-Large_Intestine-Proximal-18m-Epithelial-enteroendocrine_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CNTN4 NFASC P4HTM CD36 CFAP61	5.12e-05	180	99	5	9db9899ca42455310e9b63df523fe6c4780abfb7
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_FAM95C\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SEMA5A MCTP1 SEMA5B TENM1 PNPLA7	5.12e-05	180	99	5	b514c55e52b46e8a1a2f09ed2c59a7683367a505
ToppCell	RA-07._Pericyte\|RA / Chamber and Cluster_Paper	NFASC SEMA5A PLXND1 SEMA5B CD36	5.25e-05	181	99	5	8dfb42d096db6c2df9b41303a7199d134d4bff07
ToppCell	COVID-19-Heart-Pericyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CNTN4 NFASC SEMA5A SEMA5B CD36	5.25e-05	181	99	5	33cac65ed1ea5e7bd72250495df4f850b143d5aa
ToppCell	5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	APOB RYR2 CNTN3 PNPLA7 MDGA1	5.25e-05	181	99	5	b116c68393d8836bac080f81a8fcbeb52e0403e7
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	NEDD4L ACACA ABCA13 ITGA2 PLXNA2	5.25e-05	181	99	5	576da14ab3107f89e1f44a4a439d1bef5bb42370
ToppCell	COPD-Epithelial-Basal\|World / Disease state, Lineage and Cell class	OVCH2 NEDD4L SEMA5A ITGA2 TEAD1	5.25e-05	181	99	5	6d8a886b4afe729f8a05b9c0f4ea9375de735da4
ToppCell	RA-07._Pericyte\|World / Chamber and Cluster_Paper	CNTN4 NFASC SEMA5A PLXND1 SEMA5B	5.39e-05	182	99	5	2075efeae633550fb2eb026d0dfd741c8252482e
ToppCell	LA-07._Pericyte\|World / Chamber and Cluster_Paper	CNTN4 NFASC SEMA5A SEMA5B CD36	5.53e-05	183	99	5	e3835db4795362b0442d5893baf2a78efcc20428
ToppCell	COPD-Epithelial-Basal\|COPD / Disease state, Lineage and Cell class	OVCH2 NEDD4L SEMA5A ITGA2 TEAD1	5.53e-05	183	99	5	0f760e393edc91009bf6c7e02eeac039a1dfb4ed
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CNTN4 NEDD4L ACACA ADGRV1 CNTN3	5.68e-05	184	99	5	102105ae1a5ef6d42a43f6d9b00f12ed0690ddb7
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1-D122\|Adult / Lineage, Cell type, age group and donor	CNTN4 OVCH2 NEDD4L SEMA5A TEAD1	5.68e-05	184	99	5	561592edc3083fad41b91811151b442207c65dd9
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1\|Adult / Lineage, Cell type, age group and donor	CNTN4 OVCH2 NEDD4L SEMA5A TEAD1	6.13e-05	187	99	5	77f78aec946bc6bd85c29aee9ca978ce49f853a3
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	NEDD4L ITGA2 TEAD1 PLXNA2 EPHA4	6.29e-05	188	99	5	43a3a59f92ad93509d4166bd025aed0b1b39a008
ToppCell	PBMC-Mild-Lymphocyte-B-B_cell-B_memory-B_memory-3\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	LYPD6B CHD7 IGKC SNX2 EPHA4	6.29e-05	188	99	5	cd833a125a5279ac32a9a9cb9ecd05ae24bea3a9
ToppCell	343B-Lymphocytic-ILC\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	WWP1 HGSNAT ISOC1 TBC1D13 UTP15	6.44e-05	189	99	5	c26428871dc3261327d89cacaba6e21e004ff1f3
ToppCell	COVID-19-lung-Secretory\|lung / Disease (COVID-19 only), tissue and cell type	CNTN4 LYPD6B NEDD4L ADGRV1 CNTN3	6.44e-05	189	99	5	84d48e3ed25bebb8bb8074b3a2c5e2e88cff7f25
ToppCell	megakaryocytic-CD34+_Megakaryoblast\|World / Lineage and Cell class	LAPTM4B ITGA2 RYR2 CAPN11 SERPING1	6.61e-05	190	99	5	1d19b2bd55789bf13e1386332f46c605973d6f8e
ToppCell	COVID-19-kidney-AQP1+SLC14A1+EC\|kidney / Disease (COVID-19 only), tissue and cell type	LYPD6B PLXND1 MCTP1 PLXNA2 EPHA4	6.61e-05	190	99	5	1519f34d31fe0817184c5865a0bc9f0cb479b1a4
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	LYPD6B OVCH2 UGT3A1 MCTP1 PIK3C2G	6.77e-05	191	99	5	7235a4d1601c88a2c8af571a2c04ab56d32f1b9a
ToppCell	Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)\|World / Lineage, Cell type, age group and donor	CNTN4 OVCH2 NEDD4L ADGRV1 PLXNA2	6.77e-05	191	99	5	d3733c8c4bda70c4390e5601fdda6188a64be944
ToppCell	Children_(3_yrs)-Epithelial\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CNTN4 NEDD4L ACACA ADGRV1 TEAD1	6.77e-05	191	99	5	e432c6e1ae82dddf84314ce73d2b7a991630d905
ToppCell	Mesenchymal-vascular_smooth_muscle_cell\|World / Lineage, Cell type, age group and donor	NFASC SEMA5A RYR2 SEMA5B FOXC2	6.77e-05	191	99	5	fd89fbc62aa1c73e0f659991e3bd726a0c97bd68
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LYPD6B PLXND1 MCTP1 PLXNA2 EPHA4	6.94e-05	192	99	5	bacbaef1f230051335f4433e55db07a161b96b4c
ToppCell	Adult-Epithelial\|Adult / Lineage, Cell type, age group and donor	CNTN4 NEDD4L ACACA ADGRV1 TEAD1	6.94e-05	192	99	5	efb962a5fd3b9bdfd8cf8d13c435e29c8271713e
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_myocytic-mes_pericyte_(14)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	CNTN4 NFASC SEMA5A RYR2 SEMA5B	6.94e-05	192	99	5	5000440dc1ed17e7474d340921bdff945646f27e
ToppCell	Control-Endothelial-Endothelial-Gen_Cap\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NEDD4L ITGA2 MCTP1 CD36 GNAQ	7.11e-05	193	99	5	e1d546165dcc2392f540162206852c4717d7306f
ToppCell	(4)_Endothelial_cells-(4)_Lymph_vessel\|(4)_Endothelial_cells / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)	CNTN4 LYPD6B PIK3C2G CD36 FOXC2	7.29e-05	194	99	5	9735b86d3b2480a0b34d8aab8e7bd609d83c2454
ToppCell	LV-09._Endothelium_I\|World / Chamber and Cluster_Paper	MCTP1 CD36 GNAQ PLXNA2 EPHA4	7.47e-05	195	99	5	19e0a6c3eae1615aaa39767300acd937dfcb2a7f
ToppCell	COVID-19-Heart-EC_1\|Heart / Disease (COVID-19 only), tissue and cell type	MCTP1 CD36 GNAQ PLXNA2 EPHA4	7.47e-05	195	99	5	50a193475db1bb1e05b8590225a553688c372c14
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LYPD6B PLXND1 MCTP1 CD36 PLXNA2	7.65e-05	196	99	5	a20a56d8997d6db2a10046c8801c619a379de83c
ToppCell	3'-Adult-SmallIntestine\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	UGT3A1 APOB LCT MCTP1 CD36	7.84e-05	197	99	5	1614bc5f41fd2c8385e58ed6b87ef1536421f29a
ToppCell	distal-mesenchymal-Vascular_Smooth_Muscle-2\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CNTN4 NFASC APOB RYR2 FOXC2	7.84e-05	197	99	5	da653dc7d216e202f390e5ab0245f243e3ed213b
ToppCell	3'-Pediatric_IBD-SmallIntestine-Mesenchymal-Pericytes-Pericyte\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NFASC SEMA5A SEMA5B CD36 SERPING1	7.84e-05	197	99	5	452be45f4aac8459dd860493171f5f715368d663
ToppCell	distal-2-mesenchymal-Vascular_Smooth_Muscle\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	NFASC SEMA5A APOB RYR2 FOXC2	8.03e-05	198	99	5	ce05ede69c167b2294630709bb0c223483a6ef75
ToppCell	NS-critical-d_0-4-Myeloid-Non-resident_Macrophage\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	PLXND1 CSF1R P2RX4 CD36 SNX2	8.03e-05	198	99	5	49fc6ba574ed5c848eaa329aad1d5c8091c79f47
ToppCell	Tracheal-NucSeq-Epithelial-Epi_airway_basal-Suprabasal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	LYPD6B ABCA13 SEMA5A ITGA2 EPHA4	8.03e-05	198	99	5	19d8ff3a4f911b13ecc34844202925475ad4d2ab
ToppCell	control-HLA-DR+_CD83+_Monocyte\|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	CAPN11 CSF1R CD36 SERPING1 PGBD5	8.22e-05	199	99	5	f1b370d2869ad29c9d8ff41fdcc486fffa781ee2
ToppCell	Macroglial-Polydendrocytes-PDGFRA-\|Macroglial / cells hierarchy compared to all cells using T-Statistic	CNTN4 SEMA5A MCTP1 TENM1 CNTN3	8.41e-05	200	99	5	f17b5a54e8f9eba9dcd0808ba4e8d275ac41bce2
ToppCell	Macroglial-Polydendrocytes-PDGFRA--\|Macroglial / cells hierarchy compared to all cells using T-Statistic	CNTN4 SEMA5A MCTP1 TENM1 CNTN3	8.41e-05	200	99	5	cc3409518f8b436ea92deb955e81114b3f410ff7
ToppCell	Macroglial-Polydendrocytes-PDGFRA\|Macroglial / cells hierarchy compared to all cells using T-Statistic	CNTN4 SEMA5A MCTP1 TENM1 CNTN3	8.41e-05	200	99	5	c24a3099e3d96d8b72f6d05286bb355d661a0377
ToppCell	Macroglial-Polydendrocytes-PDGFRA---\|Macroglial / cells hierarchy compared to all cells using T-Statistic	CNTN4 SEMA5A MCTP1 TENM1 CNTN3	8.41e-05	200	99	5	4fc3de4bff7ed2bf40b38462c4b4e9b87af6a4ca
ToppCell	Tracheal-NucSeq-Stromal-Pericyte\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	NFASC SEMA5A PLXND1 SEMA5B CD36	8.41e-05	200	99	5	78cd0b7d221ef855512ee9ac9a291f61622c2e24
ToppCell	Macroglial-Polydendrocytes-PDGFRA----L1-6\|Macroglial / cells hierarchy compared to all cells using T-Statistic	CNTN4 SEMA5A MCTP1 TENM1 CNTN3	8.41e-05	200	99	5	310cd53db1c137f6af74e6ae682221d7ac27310c
ToppCell	Macroglial-Polydendrocytes\|Macroglial / cells hierarchy compared to all cells using T-Statistic	CNTN4 SEMA5A MCTP1 TENM1 CNTN3	8.41e-05	200	99	5	961858738ce35db8760c8c2e136f8369bc444ccf
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	LYPD6B OVCH2 MCTP1 PIK3C2G	1.44e-04	119	99	4	0cebbd44378c212aa0e18e4303f09eb315d02e11
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Transitional_Principal-Intercalated_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	UGT3A1 PIK3C2G UGT3A2 TDRD12	2.09e-04	131	99	4	d706405453408fbcfcabb1c7702b80f9e649ffca
ToppCell	E16.5-samps-Mesenchymal-Myofibroblast-Proliferative_Immature_MyoFibroblast\|E16.5-samps / Age Group, Lineage, Cell class and subclass	TLR6 GTF2IRD2 TENM1 PNPLA7	2.34e-04	135	99	4	ed0f94d3839eea3b60217c4352159ed481361f13
ToppCell	E16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal-Intermediate_Fibroblast\|E16.5-samps / Age Group, Lineage, Cell class and subclass	ZNF395 SERPING1 CFAP61 PGBD5	2.48e-04	137	99	4	dd5364a1002650d21e0c83d8c701b5f7b09d1c19
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-24m-Macroglial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OVCH2 EDC3 P4HTM EFNB3	2.54e-04	138	99	4	c1a46fbf1beffa12c3d1b78361e0613e2e9e2d13
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-24m-Macroglial-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OVCH2 EDC3 P4HTM EFNB3	2.84e-04	142	99	4	67d4ff3483ae34f77c3325aa0fbd3462ca19ade4
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MCTP1 PIK3C2G UGT3A2 CFAP61	3.24e-04	147	99	4	2885978bcfc5623967c0c1204dadf5c78c74a082
ToppCell	facs-Lung-3m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NFASC RYR2 CAPN11 SEMA5B	3.32e-04	148	99	4	5983c4546f527a0b599cfcbd8a6cb937a1d6f895
ToppCell	droplet-Liver-Hepatocytes-24m-Epithelial-hepatocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UGT3A1 APOB SERPING1 SERPINA7	3.58e-04	151	99	4	e243b6c76e59035f10519a86399b598dd2123f87
ToppCell	droplet-Liver-Hepatocytes-24m-Epithelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UGT3A1 APOB SERPING1 SERPINA7	3.58e-04	151	99	4	cdd2ce0969da446616627e3569bbe5a5d9b475bd
ToppCell	droplet-Liver-Hepatocytes-24m-Epithelial-Hepatocyte_(Pericentral_and_Periportal)\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UGT3A1 APOB SERPING1 SERPINA7	3.86e-04	154	99	4	a5289000597068ee8d559f89bce7bce31f35dd57
ToppCell	facs-Heart-Unknown-3m-Myeloid-monocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CNTN4 APOB PIK3C2G UGT3A2	4.15e-04	157	99	4	8d30d8e6fae93afcada6bd68799439335cd65b69
ToppCell	facs-Heart-Unknown-3m-Myeloid\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CNTN4 APOB PIK3C2G UGT3A2	4.15e-04	157	99	4	2ac4695d9e4ca8d4ba19c555e9a1d86ac8f398ab
ToppCell	facs-Heart-Unknown-3m-Myeloid-monocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CNTN4 APOB PIK3C2G UGT3A2	4.15e-04	157	99	4	8a393eece90fb9a1b7c356736bdb36277261fbd3
ToppCell	10x5'-GI_large-bowel-Lymphocytic_T_CD8-Trm/em_CD8\|GI_large-bowel / Manually curated celltypes from each tissue	DIS3L INPP5A LYST MDGA1	4.15e-04	157	99	4	d85304af4cd3b8aaedc5362a8223537e1b9dbec2
ToppCell	Adult-Mesenchymal-vascular_smooth_muscle_cell-D122\|Adult / Lineage, Cell type, age group and donor	NFASC RYR2 SEMA5B FOXC2	4.46e-04	160	99	4	fd14dfeb7021a4b7299371854dc8fc1fd66c8dae
ToppCell	facs-Heart-RV-24m-Mesenchymal-atrial_myocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CNTN4 LRGUK PGBD5 SERPINA7	4.46e-04	160	99	4	41d6c811c445c0ba9b6a2deb10a3b6b793172582
ToppCell	facs-Heart-RV-24m-Mesenchymal-atrial_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CNTN4 LRGUK PGBD5 SERPINA7	4.46e-04	160	99	4	c1d03c0ac9c12615a06499209fcdf18e9b6f1fba
ToppCell	PND10-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_prolif\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	WWP1 CSF1R P2RX4 PNPLA7	4.57e-04	161	99	4	8937f6b92cb2a93ea8c4780d9200a518c3112e53
ToppCell	droplet-Kidney-KIDNEY-30m-Epithelial-Epcam____brush_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UGT3A1 APOB CD36 UGT3A2	4.67e-04	162	99	4	de0fde4310a56dc96bfc134c44d104993526d9bc
ToppCell	facs-Pancreas-Endocrine-18m-Epithelial-pancreatic_PP_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EFNB3 TGDS TENM1 SERPINA7	4.67e-04	162	99	4	ca1014e32996f777bff021830ce9a7cf4acf58d5
ToppCell	Club-club-13\|World / Class top	ATP13A5 P2RX4 CD36 FOXC2	4.67e-04	162	99	4	7d18f05a65ac715e62d610df9cc4a26539340dee
ToppCell	Bronchial_Biopsy-Endothelial-Lymphatic\|Endothelial / Tissue, Lineage and Cell class of Lung Cells from 10X	ATP8B3 PIK3C2G CD36 FOXC2	4.78e-04	163	99	4	961c3a1303108afd680365466045f3460a30a7b0
ToppCell	Basal_cells-Donor_03\|World / lung cells shred on cell class, cell subclass, sample id	RPGRIP1 PEX1 RYR2 CNTN3	4.89e-04	164	99	4	b15a26130a1ea1b370b6e3be21f02a0d6aaf6b3c
ToppCell	343B-Lymphocytic-Plasma_cell\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	LYPD6B LRGUK KCNA2 IGKC	4.89e-04	164	99	4	cf62d34ce9dd220fe61748466c84fd70d9ba697c
ToppCell	343B-Lymphocytic-Plasma_cell-\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	LYPD6B LRGUK KCNA2 IGKC	4.89e-04	164	99	4	e00549bc8b3a5566f39031f39d7e698b0b107a7f
ToppCell	facs-Liver-Non-hepatocytes-3m-Myeloid-neutrophil\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LYPD6B CAPN1 LYST MCTP1	4.89e-04	164	99	4	8e6dbddacd56a07769163813e3ebfad13302bb62
Disease	Phakomatosis cesioflammea	GNA11 GNAQ	1.05e-05	2	96	2	C3838883
Disease	Congenital hemangioma	GNA11 GNAQ	1.05e-05	2	96	2	C0235753
Disease	Port-wine stain with oculocutaneous melanosis	GNA11 GNAQ	1.05e-05	2	96	2	C1274879
Disease	hereditary spastic paraplegia (implicated_via_orthology)	CAPN1 ATP13A5 CAPN11 PNPLA7	1.18e-05	43	96	4	DOID:2476 (implicated_via_orthology)
Disease	colorectal health	SEMA5A ADGRV1 TEAD1 RYR2 GNAQ EPHA4	5.17e-05	201	96	6	EFO_0008460
Disease	X-24544 measurement	UGT3A1 UGT3A2	6.26e-05	4	96	2	EFO_0800892
Disease	nucleotide measurement	ITGA2 JAK1 PLXNA2 PGBD5	9.64e-05	73	96	4	EFO_0010513
Disease	hereditary spastic paraplegia 76 (implicated_via_orthology)	CAPN1 CAPN11	1.04e-04	5	96	2	DOID:0110821 (implicated_via_orthology)
Disease	Malignant melanoma of iris	GNA11 GNAQ	1.04e-04	5	96	2	C0346373
Disease	Malignant melanoma of choroid	GNA11 GNAQ	1.04e-04	5	96	2	C0346388
Disease	type 2 diabetes mellitus (is_implicated_in)	APOB ITGA2 PIK3C2G CD36 FOXC2	2.46e-04	171	96	5	DOID:9352 (is_implicated_in)
Disease	attention deficit hyperactivity disorder, substance abuse, antisocial behaviour measurement	NFASC FBXO11 CHD7 TEAD1 RYR2 HHLA2 LRGUK MCTP1 CNTN3 PLXNA2	2.83e-04	801	96	10	EFO_0003888, EFO_0007052, MONDO_0002491
Disease	Uveal melanoma	GNA11 GNAQ	2.90e-04	8	96	2	C0220633
Disease	health-related quality of life measurement	SEMA5A PARP12	3.72e-04	9	96	2	EFO_0011014
Disease	smoking status measurement	CNTN4 FBXO11 CHD7 RYR2 HHLA2 LRGUK MCTP1 XRN1 CNTN3 COG5 MDGA1 PLXNA2	3.84e-04	1160	96	12	EFO_0006527
Disease	estradiol measurement	UGT3A1 FBXO11 JAK1 UGT3A2	4.67e-04	110	96	4	EFO_0004697
Disease	sitting height ratio	TEAD1 JAK1 MDGA1	6.21e-04	51	96	3	EFO_0007118
Disease	severe acute respiratory syndrome, COVID-19	ATP8B3 CNTN4 NFASC LYST SEMA5B PIK3C2G GNAQ	6.54e-04	447	96	7	EFO_0000694, MONDO_0100096
Disease	obesity (implicated_via_orthology)	PLXND1 CAPN11 CD36 GNA11 GNAQ	7.00e-04	215	96	5	DOID:9970 (implicated_via_orthology)
Disease	vascular endothelial growth factor measurement	ATP13A5 CAPN11 SEMA5B	8.16e-04	56	96	3	EFO_0004762
Disease	lung non-small cell carcinoma (is_implicated_in)	FBXO11 JAK1 CSF1R KDM6A	1.12e-03	139	96	4	DOID:3908 (is_implicated_in)
Disease	Benign Neoplasm	CAPN1 CSF1R KDM6A	1.43e-03	68	96	3	C0086692
Disease	Neoplasms	CAPN1 CSF1R KDM6A	1.43e-03	68	96	3	C0027651
Disease	Carcinoma of bladder	KDM6A EPHA4	1.55e-03	18	96	2	C0699885
Disease	mean platelet volume	EDC3 DIS3L NFASC CHD7 ITGA2 PLXND1 CD36 SERPING1 GNA11 SNX2	1.79e-03	1020	96	10	EFO_0004584
Disease	brain connectivity measurement	CNTN4 ADGRV1 JAK1 TIGD2 PLXNA2 FOXC2	1.99e-03	400	96	6	EFO_0005210
Disease	Cleft Palate	NEDD4L TGDS FOXC2	2.37e-03	81	96	3	C0008925
Disease	Immunologic Deficiency Syndromes	CHD7 CD36	2.53e-03	23	96	2	C0021051
Disease	Coronary heart disease	APOB CD36	2.76e-03	24	96	2	C0010068
Disease	blood rubidium measurement	ABCA13 MDGA1	3.24e-03	26	96	2	EFO_0021529
Disease	colon adenocarcinoma (is_implicated_in)	CSF1R KDM6A	3.24e-03	26	96	2	DOID:234 (is_implicated_in)

Protein segments in the cluster

Peptide	Gene	Start	Entry
AQATFLDYPNWNVAK	CFAP61	66	Q8NHU2
IVQISAFLYVKQQPW	ATP13A5	986	Q4VNC0
EITFNLPVKQWYFNS	ALG6	46	Q9Y672
FVVFIHAYQVKPQWK	ADGRV1	6076	Q8WXG9
TFYAQPNWIQKINDI	CNTN4	311	Q8IWV2
IEIPNFNWPQFEYVK	DUSP14	61	O95147
FNWPQFEYVKVPLAD	DUSP14	66	O95147
TPYNFEELWPKFQQI	ABCA13	2051	Q86UQ4
QVWFPDSAFKTYQAI	ACACA	2016	Q13085
VVGQKDELFNYWVFV	ATP8B3	1066	O60423
KKNYAGIFHFQIWQF	CAPN11	166	Q9UMQ6
NYPATFWVNPQFKIR	CAPN1	386	P07384
DPVKQQFDWNQFRAF	CHD7	1986	Q9P2D1
VKPQQGTAVFWYNYL	P4HTM	411	Q9NXG6
NNIWYPKFNFSKRNI	P2RX4	191	Q99571
PEWFNVYNKVQITLT	PCBD2	91	Q9H0N5
KNKIREEWNNFSYFP	JAK1	356	P23458
YLPQLVQAVKFEWNL	PIK3C2G	756	O75747
QYNVSPLSWNVAVKF	PTPN9	36	P43378
YPWFQNSSVILFLNK	GNAQ	261	P50148
VIQFNKYRDPWFSNL	KBTBD3	596	Q8NAB2
EYWKLQIFFTNVIQA	CCNC	36	P24863
AVPQEKVTYQWFKNG	MDGA1	361	Q8NFP4
RKFVVQLFAEEWGQY	ISOC1	66	Q96CN7
PENEFQRQVWLLFEY	KCNA2	141	P16389
YKNLNPEWNKVFTFN	MCTP1	666	Q6DN14
YRAFITNIPFDVKWQ	HNRNPM	71	P52272
FQWAIKAFQEVLYVD	KDM6A	146	O15550
FEIWAVNGVSKYNPN	EPHA4	411	P54764
RFWVNVIKNPQFVFD	PLXNA2	1746	O75051
FWVNILKNPQFVFDI	PLXND1	1771	Q9Y4D7
PENLQKNWLREFYQV	INPP5A	26	Q14642
IYWFNAPQIVFDACI	OR51H1	86	Q8NH63
IGQQPQAIDWLFYVK	CSNKA2IP	586	A0A1B0GTH6
VNDYFSPNQDFKVTW	HHLA2	246	Q9UM44
KQRAAWIIPFFCYQI	LAPTM4B	186	Q86VI4
QGNPVVNFTLWKYYV	LRRC49	501	Q8IUZ0
KFWITLNEPFVIAYQ	LCT	1531	P09848
FPFYRENKQGWQNSI	FOXC2	106	Q99958
ENPIQEKSEYWFFVI	LRGUK	336	Q96M69
NVFLRDQPWYKAAVA	EDC3	416	Q96F86
YPWDAVKNFLEKFVQ	ITGA2	186	P17301
IDVYGFSALWKFIQQ	PEF1	171	Q9UBV8
FKDQQIEDLWIPYFA	PNPLA7	1021	Q6ZV29
NFPPEYEKFWKTVEN	PRPF39	76	Q86UA1
YEKFWKTVENNPQDF	PRPF39	81	Q86UA1
QKVWNLFNRTLPFYF	PARP12	511	Q9H0J9
WNPKIFVVFDANQIY	PARP11	316	Q9NR21
YFISHKPNKTWQQVF	PGBD5	461	Q8N414
YVVQFEEDQFQPGVW	NFASC	661	O94856
IVKDGQPEIFYTFWN	COG5	371	Q9UP83
FPDSVNKALYWVNGQ	APOB	711	P04114
YNEKWEFPRNNLQFG	CSF1R	571	P07333
FIPANVVLKWYENFQ	HIKESHI	171	Q53FT3
LDTPAKQVLWQFIYQ	GRID2IP	436	A4D2P6
YKAQPFDLQEAVEWF	SDR42E1	336	Q8WUS8
IENKIYANNFAGVWI	FBXO11	516	Q86XK2
VYRQFWIFDVQNPQE	CD36	61	P16671
FVITFKNYLDNFWPD	DIS3L	181	Q8TF46
YPWFQNSSVILFLNK	GNA11	261	P29992
FEVQQPFLFVLWDQQ	SERPING1	471	P05155
VQWKLYNYIFNPVLQ	LYST	726	Q99698
NFYPREAKVQWKVDN	IGKC	31	P01834
KPQEWDAQFFNYQRL	MAN2A2	431	P49641
VFENYFPFQWKLKDN	HGSNAT	616	Q68CP4
FNKKWNLPVYFQIRF	COG2	376	Q14746
FWKYLVNPEGQVVKF	GPX8	166	Q8TED1
KWERAYFFVEVQNIP	GTF2IRD2	431	Q86UP8
KWERAYFFVEVQNIP	GTF2IRD2B	431	Q6EKJ0
EPVYWNSANKRFQAE	EFNB3	31	Q15768
AYVQQIFVKSSVFPW	SCAP	91	Q12770
NTQSFPNNYWDKFVK	RYR2	4636	Q92736
AIFPVWVDQQTYIFI	PEX1	141	O43933
NPWVEYEFRVVASNK	CNTN3	666	Q9P232
LYNFDNPWNFQNIPK	MIA2	461	Q96PC5
WNNYKTPVQIKEFGA	UTP15	26	Q8TED0
QQQLIKYWEAFLPEA	SNX2	501	O60749
NGSIQVQLDWKFPYI	RPGRIP1	916	Q96KN7
IVPAKKWDNAAIQYF	TDRD12	146	Q587J7
QPSVIWIGNAEKNFY	IQCA1L	621	A6NCM1
SLVKVQPWNYFNIFS	OVCH2	36	Q7RTZ1
PAEYFWTINGKFQQS	PSG9	361	Q00887
FPAAINLVYTFAWNK	TENM1	1071	Q9UKZ4
VVLWAIFANKEPYEN	RIPK1	216	Q13546
TAQYNSKWLNEPNFV	SEMA5A	206	Q13591
FVQSYWEQYKFPVVI	TGDS	176	O95455
VFRQWFEKYFVPQVQ	TIGD2	261	Q4W5G0
FQQPWHEQYLIDVFV	UGT3A1	476	Q6NUS8
VNYIHFKAQWANPFD	SERPINA7	201	P05543
QQVAFQPGQKVYVWY	ZNF395	71	Q9H8N7
LEKQWSKQVVPFVYQ	XRN1	816	Q8IZH2
LQEQNIKPQFFAFRW	TBC1D13	306	Q9NVG8
QYNSKWLNEPNFVAA	SEMA5B	276	Q9P283
QFLWPKPVEYLNIYN	TLR6	271	Q9Y2C9
WYPKANNQDFIPFTK	ZC2HC1C	116	Q53FD0
LKYFPVTNDNNAWVR	ZBED5	561	Q49AG3
PQNAFFLVKFWADLN	TEAD1	281	P28347
FQQPWHEQYLLDVFV	UGT3A2	476	Q3SY77
NEVVPLQWLQYFDEK	WWP1	781	Q9H0M0
RFWSNPYFQNKVIVK	TSPY26P	241	Q9H489
WAFAKNINFYNVRPP	LYPD6B	36	Q8NI32
NPKWNEEFYFRVNPS	NEDD4L	71	Q96PU5