Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionolfactory receptor activity

OR7C2 OR7A5 OR4K13 OR1F2P OR6X1 OR4A5 OR1A1 OR2A25 OR4K5 OR8G5 OR7A17 OR4K15 OR7A10

1.87e-0543114713GO:0004984
GeneOntologyBiologicalProcessdetection of chemical stimulus involved in sensory perception of smell

OR7C2 OR7A5 OR4K13 OR1F2P OR6X1 OR4A5 OR1A1 OR2A25 OR4K5 OR8G5 OR7A17 OR4K15 OR7A10

1.09e-0543214413GO:0050911
GeneOntologyBiologicalProcesssensory perception of smell

OR7C2 OR7A5 OR4K13 OR1F2P OR6X1 OR4A5 OR1A1 OR2A25 OR4K5 OR8G5 OR7A17 OR4K15 OR7A10

2.37e-0546514413GO:0007608
GeneOntologyBiologicalProcessdetection of chemical stimulus involved in sensory perception

OR7C2 OR7A5 OR4K13 OR1F2P OR6X1 OR4A5 OR1A1 OR2A25 OR4K5 OR8G5 OR7A17 OR4K15 OR7A10

3.67e-0548514413GO:0050907
GeneOntologyBiologicalProcessdetection of stimulus involved in sensory perception

OR7C2 OR7A5 OR4K13 OR1F2P OR6X1 OR4A5 GUCY2F OR1A1 OR2A25 OR4K5 OR8G5 OR7A17 OR4K15 OR7A10

5.91e-0558214414GO:0050906
GeneOntologyBiologicalProcessdetection of chemical stimulus

OR7C2 OR7A5 OR4K13 OR1F2P OR6X1 OR4A5 OR1A1 OR2A25 OR4K5 OR8G5 OR7A17 OR4K15 OR7A10

8.05e-0552414413GO:0009593
GeneOntologyCellularComponentpolar microtubule

TUBG1 KLHL21 TUBGCP3

3.37e-0651473GO:0005827
GeneOntologyCellularComponentspindle microtubule

TUBG2 NUMA1 TUBG1 RMDN3 KLHL21 TUBGCP3

3.23e-05861476GO:0005876
GeneOntologyCellularComponentmicrotubule

TUBG2 NUMA1 SAXO2 DNAH7 TUBG1 DNAH1 GRIP1 RMDN3 SLC8A1 KLHL21 TUBGCP3 KIF3C

3.96e-0453314712GO:0005874
GeneOntologyCellularComponentgamma-tubulin complex

TUBG2 TUBG1 TUBGCP3

4.13e-04211473GO:0000930
GeneOntologyCellularComponentsite of polarized growth

ADCY10 FRMD7 FRYL TIAM2 TAOK2 RAPGEF3 DOCK7 KIF3C

4.33e-042531478GO:0030427
GeneOntologyCellularComponentneuronal cell body

ADCY10 RELN FRMD7 NUMA1 IREB2 CNKSR2 ADCYAP1 TIAM2 GRIP1 SLC8A1 RAPGEF3 LNPEP KIF3C BSN CREB3

8.16e-0483514715GO:0043025
GeneOntologyCellularComponentcytoplasmic region

NUMA1 SAXO2 ATG14 DNAH7 DNAH1 GLI2 KIF3C BSN PHLDB2

1.03e-033601479GO:0099568
GeneOntologyCellularComponentdistal axon

ADCY10 FRMD7 ADCYAP1 TIAM2 TAOK2 GRIP1 SLC8A1 RAPGEF3 DOCK7 KIF3C

1.04e-0343514710GO:0150034
DomainOlfact_rcpt

OR7C2 OR7A5 OR4K13 OR1F2P OR6X1 OR4A5 OR1A1 OR2A25 OR4K5 OR8G5 OR7A17 OR4K15 OR7A10

1.32e-0539314613IPR000725
DomainGamma_tubulin

TUBG2 TUBG1

6.07e-0521462IPR002454
DomainDUF2075

SLFN13 SLFN11

1.81e-0431462PF09848
DomainDUF2075

SLFN13 SLFN11

1.81e-0431462IPR018647
Domain-

ADCY10 GUCY2F GUCY2D

3.50e-041814633.30.70.1230
DomainNucleotide_cyclase

ADCY10 GUCY2F GUCY2D

3.50e-04181463IPR029787
DomainPecanex_C

PCNX3 PCNX2

3.60e-0441462PF05041
DomainPecanex

PCNX3 PCNX2

3.60e-0441462IPR007735
DomainGuanylate_cyc

ADCY10 GUCY2F GUCY2D

4.14e-04191463PF00211
DomainGUANYLATE_CYCLASE_2

ADCY10 GUCY2F GUCY2D

4.14e-04191463PS50125
DomainA/G_cyclase

ADCY10 GUCY2F GUCY2D

4.14e-04191463IPR001054
DomainGUANYLATE_CYCLASE_1

ADCY10 GUCY2F GUCY2D

4.14e-04191463PS00452
DomainCYCc

ADCY10 GUCY2F GUCY2D

4.14e-04191463SM00044
DomainUDPGT

UGT1A5 UGT1A3 UGT3A2

5.61e-04211463PF00201
DomainUDPGT

UGT1A5 UGT1A3 UGT3A2

5.61e-04211463PS00375
DomainUDP_glucos_trans

UGT1A5 UGT1A3 UGT3A2

5.61e-04211463IPR002213
Domain-

RELN NEU3

5.98e-04514622.120.10.10
DomainHNOB_dom_associated

GUCY2F GUCY2D

8.92e-0461462IPR011645
DomainHNOBA

GUCY2F GUCY2D

8.92e-0461462PF07701
DomainAlbA_2

SLFN13 SLFN11

1.24e-0371462PF04326
DomainSchlafen

SLFN13 SLFN11

1.24e-0371462IPR029684
DomainSchlafen_AAA_dom

SLFN13 SLFN11

1.24e-0371462IPR007421
PathwayKEGG_OLFACTORY_TRANSDUCTION

OR7C2 OR7A5 OR4K13 OR6X1 OR4A5 GUCY2D OR1A1 OR2A25 OR4K5 OR8G5 OR7A17 OR4K15 OR7A10

9.36e-0638910913M14091
PathwayREACTOME_OLFACTORY_SIGNALING_PATHWAY

OR7C2 OR7A5 OR4K13 OR6X1 OR4A5 OR1A1 OR2A25 OR4K5 OR8G5 OR7A17 OR4K15 OR7A10

9.00e-0541710912M4072
PathwayREACTOME_SENSORY_PERCEPTION

OR7C2 OR7A5 OR4K13 OR6X1 OR4A5 GUCY2F GUCY2D OR1A1 OR2A25 OR4K5 OR8G5 OR7A17 BSN OR4K15 OR7A10

1.10e-0463610915M41834
Pubmed

The olfactory receptor gene repertoire in primates and mouse: evidence for reduction of the functional fraction in primates.

OR7C2 OR7A5 OR1F2P OR1A1 OR7A17 OR7A10

5.53e-1023150610706615
Pubmed

Different evolutionary processes shaped the mouse and human olfactory receptor gene families.

OR7C2 OR7A5 OR1F2P OR6X1 OR4A5 OR1A1 OR2A25 OR4K5 OR8G5 OR7A17 OR4K15 OR7A10

3.24e-083401501211875048
Pubmed

The olfactory receptor gene superfamily of the mouse.

OR7C2 OR7A5 OR1F2P OR6X1 OR4A5 OR1A1 OR2A25 OR4K5 OR8G5 OR7A17 OR4K15 OR7A10

3.24e-083401501211802173
Pubmed

A unified nomenclature for vertebrate olfactory receptors.

OR7C2 OR7A5 OR1F2P OR6X1 OR4A5 OR1A1 OR2A25 OR4K5 OR8G5 OR7A17 OR4K15 OR7A10

3.57e-083431501232295537
Pubmed

Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels.

OR7C2 OR7A5 OR1F2P OR6X1 OR4A5 OR1A1 OR2A25 OR4K5 OR8G5 OR7A17 OR4K15 OR7A10

3.93e-083461501214611657
Pubmed

Direct binding of NuMA to tubulin is mediated by a novel sequence motif in the tail domain that bundles and stabilizes microtubules.

TUBG2 NUMA1 TUBG1 TUBGCP3

4.12e-089150411956313
Pubmed

Dynamic changes of NuMA during the cell cycle and possible appearance of a truncated form of NuMA during apoptosis.

TUBG2 NUMA1 TUBG1 TUBGCP3

4.12e-08915048838651
Pubmed

Characterization of the human homologue of the yeast spc98p and its association with gamma-tubulin.

TUBG2 TUBG1 TUBGCP3

7.86e-08315039566969
Pubmed

Strabismus regulates asymmetric cell divisions and cell fate determination in the mouse brain.

RELN TUBG2 NUMA1 TUBG1

5.81e-0716150419332887
Pubmed

Odorant and vomeronasal receptor genes in two mouse genome assemblies.

OR7C2 OR4A5 OR1A1 OR7A17 OR4K15 OR7A10

8.47e-0774150615081110
Pubmed

Visualizing an olfactory sensory map.

OR7A5 OR7A17 OR7A10

1.56e-06615038929536
Pubmed

DOCK7 interacts with TACC3 to regulate interkinetic nuclear migration and cortical neurogenesis.

TUBG2 TUBG1 DOCK7

1.56e-066150322842144
Pubmed

The AP-2 complex interacts with γ-TuRC and regulates the proliferative capacity of neural progenitors.

TUBG2 TUBG1 TUBGCP3

4.33e-068150338086550
Pubmed

The human olfactory receptor gene family.

OR7C2 OR7A5 OR4K13 OR1F2P OR6X1 OR4A5 OR1A1 OR4K5 OR8G5 OR7A17 OR4K15 OR7A10

4.39e-065411501214983052
Pubmed

Mammalian neurogenesis requires Treacle-Plk1 for precise control of spindle orientation, mitotic progression, and maintenance of neural progenitor cells.

RELN TUBG2 TUBG1

9.23e-0610150322479190
Pubmed

Intraflagellar transport 88 (IFT88) is crucial for craniofacial development in mice and is a candidate gene for human cleft lip and palate.

TUBG2 TUBG1 GLI2

1.68e-0512150328069795
Pubmed

Identification of ligands for olfactory receptors by functional expression of a receptor library.

OR1A1 OR7A17 OR7A10

1.68e-051215039875846
Pubmed

Cloning and characterization of cDNAs encoding mouse Ugt1.6 and rabbit UGT1.6: differential induction by 2,3,7,8-tetrachlorodibenzo-p-dioxin.

UGT1A5 UGT1A3

1.85e-05215028068691
Pubmed

Cloning and expression of a second photoreceptor-specific membrane retina guanylyl cyclase (RetGC), RetGC-2.

GUCY2F GUCY2D

1.85e-05215027777544
Pubmed

Epac mediates PACAP-dependent long-term depression in the hippocampus.

ADCYAP1 RAPGEF3

1.85e-052150219001039
Pubmed

MTOC reorientation occurs during FcgammaR-mediated phagocytosis in macrophages.

TUBG2 TUBG1

1.85e-052150217442887
Pubmed

Overexpression of γ-tubulin in non-small cell lung cancer.

TUBG2 TUBG1

1.85e-052150222806905
Pubmed

SCR: novel human suppressors of cdc2/cdc13 mutants of Schizosaccharomyces pombe harbour motifs for RNA binding proteins.

RBMS1 RBMS2

1.85e-05215028041632
Pubmed

Allocation of gamma-tubulin between oocyte cortex and meiotic spindle influences asymmetric cytokinesis in the mouse oocyte.

TUBG2 TUBG1

1.85e-052150217287496
Pubmed

Differential expression of human γ-tubulin isotypes during neuronal development and oxidative stress points to a γ-tubulin-2 prosurvival function.

TUBG2 TUBG1

1.85e-052150228119396
Pubmed

Amplification-driven BCL6-suppressed cytostasis is mediated by transrepression of FOXO3 and post-translational modifications of FOXO3 in urinary bladder urothelial carcinoma.

FOXO3 BCL6

1.85e-052150231903146
Pubmed

Structures and comparison of genomic and complementary DNAs of mouse MSSP, a c-Myc binding protein.

RBMS1 RBMS2

1.85e-052150210639566
Pubmed

The function of guanylate cyclase 1 and guanylate cyclase 2 in rod and cone photoreceptors.

GUCY2F GUCY2D

1.85e-052150217255100
Pubmed

Mouse Slfn8 and Slfn9 genes complement human cells lacking SLFN11 during the replication stress response.

SLFN13 SLFN11

1.85e-052150237833372
Pubmed

Gene knockout analysis of two gamma-tubulin isoforms in mice.

TUBG2 TUBG1

1.85e-052150215893303
Pubmed

Attenuated demyelination in the absence of the macrophage-restricted adhesion molecule sialoadhesin (Siglec-1) in mice heterozygously deficient in P0.

MPZ SIGLEC1

1.85e-052150216458537
Pubmed

Structure of Schlafen13 reveals a new class of tRNA/rRNA- targeting RNase engaged in translational control.

SLFN13 SLFN11

1.85e-052150229563550
Pubmed

Evolution of odorant receptors expressed in mammalian testes.

OR7A5 OR7A17 OR7A10

2.18e-0513150311014824
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

FOXO3 HIVEP2 PCNX3 PPRC1 HECTD4 FRYL TUBG1 TIAM2 TAOK2 PCNX2 PIAS4 ZNRF3 KLHL21 SORBS3 AP1G2 CREB3

2.47e-0511051501635748872
Pubmed

Notochord-derived Shh concentrates in close association with the apically positioned basal body in neural target cells and forms a dynamic gradient during neural patterning.

TUBG2 TUBG1 GLI2

4.23e-0516150318272593
Pubmed

Chromosomal location-dependent nonstochastic onset of odor receptor expression.

OR7A5 OR7A17 OR7A10

5.12e-0517150320668191
Pubmed

Isolation and characterization of a UDP-glucuronosyltransferase (UGT1A01) cloned from female rhesus monkey.

UGT1A5 UGT1A3

5.53e-053150212051676
Pubmed

Retinal degeneration-3 protein attenuates photoreceptor degeneration in transgenic mice expressing dominant mutation of human retinal guanylyl cyclase.

GUCY2F GUCY2D

5.53e-053150234537244
Pubmed

CDK5RAP2 is a pericentriolar protein that functions in centrosomal attachment of the gamma-tubulin ring complex.

TUBG1 TUBGCP3

5.53e-053150217959831
Pubmed

Comparison of germinal center markers CD10, BCL6 and human germinal center-associated lymphoma (HGAL) in follicular lymphomas.

BCL6 GCSAM

5.53e-053150221988858
Pubmed

Schlafen 11 triggers innate immune responses through its ribonuclease activity upon detection of single-stranded DNA.

SLFN13 SLFN11

5.53e-053150238875319
Pubmed

A role for UDP-glucose glycoprotein glucosyltransferase in expression and quality control of MHC class I molecules.

UGT1A5 UGT1A3

5.53e-053150221383159
Pubmed

The gamma-tubulin gene family in humans.

TUBG2 TUBG1

5.53e-053150210903841
Pubmed

FoxO3a and BCR-ABL regulate cyclin D2 transcription through a STAT5/BCL6-dependent mechanism.

FOXO3 BCL6

5.53e-053150215509806
Pubmed

Assessment of expression and specific activities of transglutaminases TG1, TG2, and FXIII-A during osteoclastogenesis.

F13A1 TGM1

5.53e-053150231786225
Pubmed

Human TUBG2 gene is expressed as two splice variant mRNA and involved in cell growth.

TUBG2 TUBG1

5.53e-053150227015882
Pubmed

The Aurora A-HP1γ pathway regulates gene expression and mitosis in cells from the sperm lineage.

TUBG2 TUBG1

5.53e-053150226021315
Pubmed

Interaction of PACAP with Sonic hedgehog reveals complex regulation of the hedgehog pathway by PKA.

ADCYAP1 GLI2

5.53e-053150223872071
Pubmed

Huntingtin regulates mammary stem cell division and differentiation.

TUBG2 NUMA1 TUBG1

6.12e-0518150324749073
Pubmed

Loss of Dmrt5 Affects the Formation of the Subplate and Early Corticogenesis.

RELN TUBG2 TUBG1

7.24e-0519150331845734
Pubmed

Forward genetics uncovers Transmembrane protein 107 as a novel factor required for ciliogenesis and Sonic hedgehog signaling.

TUBG2 TUBG1 GLI2

7.24e-0519150322698544
Pubmed

Defining the human C2H2 zinc finger degrome targeted by thalidomide analogs through CRBN.

BCL6 OSR1 CRBN

7.24e-0519150330385546
Pubmed

Cell cycle-related kinase regulates mammalian eye development through positive and negative regulation of the Hedgehog pathway.

TUBG2 TUBG1 GLI2

7.24e-0519150329166577
Pubmed

Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

ATG14 CNKSR2 FRYL ABLIM3 TAOK2

7.56e-05100150510048485
Pubmed

Cell Metabolic Alterations due to Mcph1 Mutation in Microcephaly.

TUBG2 TUBG1 DOCK7

8.49e-0520150332294449
Pubmed

Disruption of Mks1 localization to the mother centriole causes cilia defects and developmental malformations in Meckel-Gruber syndrome.

TUBG2 TUBG1 GLI2

8.49e-0520150321045211
Pubmed

Planar cell polarity effector gene Intu regulates cell fate-specific differentiation of keratinocytes through the primary cilia.

TUBG2 TUBG1 GLI2

9.88e-0521150322935613
Pubmed

Wdpcp promotes epicardial EMT and epicardium-derived cell migration to facilitate coronary artery remodeling.

TUBG2 TUBG1 GLI2

9.88e-0521150329487191
Pubmed

Protein kinase A acts at the basal body of the primary cilium to prevent Gli2 activation and ventralization of the mouse neural tube.

TUBG2 TUBG1 GLI2

9.88e-0521150322007132
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

WASHC4 HECTD4 ECPAS TIAM2 TAOK2 KLHL21 CCSER2 BSN NBR1 ZMYM4

1.07e-045291501014621295
Pubmed

RD3, the protein associated with Leber congenital amaurosis type 12, is required for guanylate cyclase trafficking in photoreceptor cells.

GUCY2F GUCY2D

1.10e-044150221078983
Pubmed

Cilia organize ependymal planar polarity.

TUBG2 TUBG1

1.10e-044150220164345
Pubmed

Control of steroid, heme, and carcinogen metabolism by nuclear pregnane X receptor and constitutive androstane receptor.

UGT1A5 UGT1A3

1.10e-044150212644700
Pubmed

Stability of the small gamma-tubulin complex requires HCA66, a protein of the centrosome and the nucleolus.

TUBG1 TUBGCP3

1.10e-044150219299467
Pubmed

Retinal guanylyl cyclase isozyme 1 is the preferential in vivo target for constitutively active GCAP1 mutants causing congenital degeneration of photoreceptors.

GUCY2F GUCY2D

1.10e-044150222623665
Pubmed

Loss of Necdin impairs myosin activation and delays cell polarization.

TUBG2 TUBG1

1.10e-044150220665884
Pubmed

Genomic sequencing reveals the structure of the Kcnk6 and map3k11 genes and their close vicinity to the sipa1 gene on mouse chromosome 19.

PCNX3 KCNK7

1.10e-044150210894943
Pubmed

The kinase homology domain of retinal guanylyl cyclases 1 and 2 specifies the affinity and cooperativity of interaction with guanylyl cyclase activating protein-2.

GUCY2F GUCY2D

1.10e-04415029698373
Pubmed

Piezo mechanosensory channels regulate centrosome integrity and mitotic entry.

TUBG2 TUBG1

1.10e-044150236574677
Pubmed

Aspm specifically maintains symmetric proliferative divisions of neuroepithelial cells.

TUBG2 TUBG1

1.10e-044150216798874
Pubmed

The autophagy-related gene 14 (Atg14) is regulated by forkhead box O transcription factors and circadian rhythms and plays a critical role in hepatic autophagy and lipid metabolism.

FOXO3 ATG14

1.10e-044150222992773
Pubmed

DIAPH3 deficiency links microtubules to mitotic errors, defective neurogenesis, and brain dysfunction.

TUBG2 NUMA1 TUBG1

1.14e-0422150333899739
Pubmed

Broad-minded links cell cycle-related kinase to cilia assembly and hedgehog signal transduction.

TUBG2 TUBG1 GLI2

1.14e-0422150320159594
Pubmed

Primary cilia regulate hippocampal neurogenesis by mediating sonic hedgehog signaling.

TUBG2 TUBG1 GLI2

1.31e-0423150318728187
Pubmed

DOT1L promotes progenitor proliferation and primes neuronal layer identity in the developing cerebral cortex.

RELN TUBG2 TUBG1

1.31e-0423150330329130
Pubmed

Specific repertoire of olfactory receptor genes in the male germ cells of several mammalian species.

OR7A5 OR7A17 OR7A10

1.49e-042415039119360
Pubmed

Expression of members of the putative olfactory receptor gene family in mammalian germ cells.

OR7A5 OR1F2P OR7A17

1.69e-042515031370859
Pubmed

Primary cilia dynamics instruct tissue patterning and repair of corneal endothelium.

TUBG2 TUBG1

1.83e-045150221285373
Pubmed

Sipa1 is a candidate for underlying the metastasis efficiency modifier locus Mtes1.

PCNX3 KCNK7

1.83e-045150216142231
Pubmed

A Rap guanine nucleotide exchange factor enriched highly in the basal ganglia.

TIAM2 RAPGEF3

1.83e-04515029789079
Pubmed

Subcellular localization of the Schlafen protein family.

SLFN13 SLFN11

1.83e-045150218355440
Pubmed

Primary Ciliary Dyskinesia Associated Disease-Causing Variants in CCDC39 and CCDC40 Cause Axonemal Absence of Inner Dynein Arm Heavy Chains DNAH1, DNAH6, and DNAH7.

DNAH7 DNAH1

1.83e-045150239056782
Pubmed

Analysis of Ellis van Creveld syndrome gene products: implications for cardiovascular development and disease.

TUBG2 TUBG1

1.83e-045150219251731
Pubmed

The essential role of centrosomal NDE1 in human cerebral cortex neurogenesis.

TUBG2 TUBG1

1.83e-045150221529752
Pubmed

Monocilia in the embryonic mouse heart suggest a direct role for cilia in cardiac morphogenesis.

TUBG2 TUBG1

1.83e-045150218729223
Pubmed

WDR62 is associated with the spindle pole and is mutated in human microcephaly.

TUBG2 TUBG1

1.83e-045150220890279
Pubmed

Speriolin is a novel human and mouse sperm centrosome protein.

TUBG2 TUBG1

1.83e-045150220542897
Pubmed

Novel Jbts17 mutant mouse model of Joubert syndrome with cilia transition zone defects and cerebellar and other ciliopathy related anomalies.

TUBG2 TUBG1

1.83e-045150225877302
Pubmed

Expression and regulatory effects of murine Schlafen (Slfn) genes in malignant melanoma and renal cell carcinoma.

SLFN13 SLFN11

1.83e-045150224089532
Pubmed

Functional Study and Mapping Sites for Interaction with the Target Enzyme in Retinal Degeneration 3 (RD3) Protein.

GUCY2F GUCY2D

1.83e-045150227471269
Pubmed

Conditional knockout mice for the distal appendage protein CEP164 reveal its essential roles in airway multiciliated cell differentiation.

TUBG2 TUBG1

1.83e-045150229244804
Pubmed

Mutations in the Heterotopia Gene Eml1/EML1 Severely Disrupt the Formation of Primary Cilia.

TUBG2 TUBG1

1.83e-045150231390572
Pubmed

Enzymatic relay mechanism stimulates cyclic GMP synthesis in rod photoresponse: biochemical and physiological study in guanylyl cyclase activating protein 1 knockout mice.

GUCY2F GUCY2D

1.83e-045150223082185
Pubmed

A two-kinesin mechanism controls neurogenesis in the developing brain.

TUBG2 TUBG1

1.83e-045150238040957
Pubmed

Regulation of microtubule formation in activated mast cells by complexes of gamma-tubulin with Fyn and Syk kinases.

TUBG2 TUBG1

1.83e-045150216751367
Pubmed

A maternal store of macroH2A is removed from pronuclei prior to onset of somatic macroH2A expression in preimplantation embryos.

TUBG2 TUBG1

1.83e-045150215680357
Pubmed

Isolation of cDNAs for mouse phenol and bilirubin UDP-glucuronosyltransferases and mapping of the mouse gene for phenol UDP-glucuronosyltransferase (Ugtla1) to chromosome 1 by restriction fragment length variations.

UGT1A5 UGT1A3

1.83e-04515027677729
Pubmed

Schlafen-8 is essential for lymphatic endothelial cell activation in experimental autoimmune encephalomyelitis.

SLFN13 SLFN11

1.83e-045150229528433
Pubmed

Enzymatic properties and regulation of the native isozymes of retinal membrane guanylyl cyclase (RetGC) from mouse photoreceptors.

GUCY2F GUCY2D

1.83e-045150221598940
Pubmed

HIV-1 Vpr induces defects in mitosis, cytokinesis, nuclear structure, and centrosomes.

TUBG2 TUBG1

1.83e-045150214767062
GeneFamilyGuanylate cyclase receptors

GUCY2F GUCY2D

6.12e-047992343
GeneFamilySchlafen family

SLFN13 SLFN11

6.12e-0479921110
GeneFamilyUDP glucuronosyltransferases

UGT1A5 UGT1A3 UGT3A2

7.04e-0432993363
GeneFamilyTransglutaminases

F13A1 TGM1

1.04e-039992773
GeneFamilyWD repeat domain containing

WIPI1 PPWD1 THOC6 TBC1D31 DCAF10 WDR87

3.19e-03262996362
GeneFamilyOlfactory receptors, family 7

OR7C2 OR7A5 OR7A17 OR7A10

3.45e-03113994154
GeneFamilyDyneins, axonemal

DNAH7 DNAH1

3.83e-0317992536
GeneFamilyZinc fingers ZZ-type|Lysine acetyltransferases

ZSWIM2 NBR1

4.29e-031899291
GeneFamilyOlfactory receptors, family 4

OR4K13 OR4A5 OR4K5 OR4K15

5.52e-03129994151
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

ARHGEF5 ECT2L TIAM2

5.68e-0366993722
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MGAM RELN CNKSR2 NEB DNAH1 SLC8A1 GUCY2F DISP3 ADGRL3

1.33e-0818415092cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MGAM RELN CNKSR2 NEB DNAH1 SLC8A1 GUCY2F DISP3 ADGRL3

1.33e-081841509ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MGAM RELN CNKSR2 NEB DNAH1 SLC8A1 GUCY2F DISP3 ADGRL3

1.33e-0818415092b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L5_PT|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

RELN RBMS1 SGPP2 BCL6 ADCYAP1 TIAM2

8.07e-0614015067cc891d676555609add6fc7880735d948a2ad801
ToppCellPosterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

CNKSR2 ADCYAP1 CFAP65 PCNX2 NDST3 CCDC87

9.11e-0614315065fb5a4ea93e5cce55d427e3b4a50a979504fad3c
ToppCellPosterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Bcl6|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

SGPP2 BCL6 ADCYAP1 CFAP65 NDST3 CCDC87

9.48e-06144150608005be9e3367f78ef27e125d9cce5ca53f4bd2d
ToppCellfacs-Lung-18m-Hematologic-myeloid-leukocyte|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CD177 BCL6 F13A1 PCNX2 TGM1 SIGLEC1

1.34e-0515315068cc2667213bfac37545bb63181e88ef1f1834413
ToppCellfacs-Lung-18m-Hematologic-myeloid-leukocyte-proliferating_myeloid_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CD177 BCL6 F13A1 PCNX2 TGM1 SIGLEC1

1.34e-051531506596bb7cfd1c713708ce73df30d890a0233eae7f7
ToppCell3'-Airway_Nasal-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADCYAP1 TIAM2 FSIP2 GPR137C RAPGEF3 KIF3C

2.59e-05172150613d7117f92a92d77d6b4335ed800c585dc8b4511
ToppCell3'-Airway_Nasal-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells-Mast_cells_L.1.4.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADCYAP1 TIAM2 FSIP2 GPR137C RAPGEF3 KIF3C

2.59e-0517215063d83b2f03ad3af4dae3fe6cc0a0ef356872ca94f
ToppCell3'-Airway_Nasal-Immune_Myeloid_mast-Myeloid_Mast/Baso|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADCYAP1 TIAM2 FSIP2 GPR137C RAPGEF3 KIF3C

2.59e-051721506a3d431aed12c1192e8dca1dc85b8340fb7354f8d
ToppCell3'-Airway_Nasal-Immune_Myeloid_mast|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADCYAP1 TIAM2 FSIP2 GPR137C RAPGEF3 KIF3C

2.59e-051721506028a5441242b2cc760cafc1822120180619c63ae
ToppCell3'-Airway_Nasal-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADCYAP1 TIAM2 FSIP2 GPR137C RAPGEF3 KIF3C

2.59e-0517215069fc70b1a143a8ec910336c23b761d908bb6aecb2
Diseasecomplex cortical dysplasia with other brain malformations 4 (implicated_via_orthology)

TUBG2 TUBG1

2.20e-0521392DOID:0090138 (implicated_via_orthology)
Diseasebilirubin measurement

FAM234A WIPI1 UGT1A5 SGPP2 BCL6 PTGR3 UGT1A3 GLI2 DOCK7

2.58e-044421399EFO_0004570
Diseasepermanent dental caries

MGAM MAP3K7

4.56e-0471392EFO_0600096
DiseaseX-11793--oxidized bilirubin measurement

UGT1A5 UGT1A3

6.06e-0481392EFO_0021260
DiseaseSuccinimide measurement

UGT1A5 UGT1A3

6.06e-0481392EFO_0022118
DiseaseX-11530 measurement

UGT1A5 UGT1A3

6.06e-0481392EFO_0021249
Diseasesulfate of piperine metabolite C16H19NO3 (2) measurement

UGT1A5 UGT1A3

6.06e-0481392EFO_0801034
Diseasecholelithiasis, bilirubin measurement

UGT1A5 UGT1A3

6.06e-0481392EFO_0004570, EFO_0004799
DiseaseX-11522 measurement

UGT1A5 UGT1A3

6.06e-0481392EFO_0800696
DiseaseX-10458 measurement

UGT1A5 UGT1A3

6.06e-0481392EFO_0800692
DiseaseX-24849 measurement

UGT1A5 UGT1A3

6.06e-0481392EFO_0800909
Diseasemembrane-associated progesterone receptor component 1 measurement

UGT1A5 UGT1A3

6.06e-0481392EFO_0802740
DiseaseX-16946 measurement

UGT1A5 UGT1A3

6.06e-0481392EFO_0800766
Diseasehormone measurement

UGT1A5 SGPP2 UGT1A3 SLC8A1

6.80e-04841394EFO_0004730
DiseaseX-11442 measurement

UGT1A5 UGT1A3

7.76e-0491392EFO_0021236
DiseaseX-11441 measurement

UGT1A5 UGT1A3

7.76e-0491392EFO_0021235
Diseasecirculating cell free DNA measurement

UGT1A5 UGT1A3

7.76e-0491392EFO_0004739
Diseasesulfate of piperine metabolite C18H21NO3 (3) measurement

UGT1A5 UGT1A3

7.76e-0491392EFO_0801037
Diseasesulfate of piperine metabolite C18H21NO3 (1) measurement

UGT1A5 UGT1A3

7.76e-0491392EFO_0801036
DiseaseX-11880 measurement

UGT1A5 UGT1A3

7.76e-0491392EFO_0800698
Diseaseprotein-tyrosine kinase 6 measurement

UGT1A5 UGT1A3

7.76e-0491392EFO_0020691
Diseasetestis-specific chromodomain protein Y 1 measurement

UGT1A5 UGT1A3

7.76e-0491392EFO_0802127
Diseasebilirubin measurement, response to xenobiotic stimulus

UGT1A5 UGT1A3

7.76e-0491392EFO_0004570, GO_0009410
Diseasebilirubin measurement, response to tenofovir

UGT1A5 UGT1A3

9.67e-04101392EFO_0004570, EFO_0009279
DiseaseX-21448 measurement

UGT1A5 UGT1A3

9.67e-04101392EFO_0800816
DiseaseUDP-glucuronosyltransferase 1-6 measurement

UGT1A5 UGT1A3

9.67e-04101392EFO_0802185
DiseaseHoloprosencephaly sequence

PRRX1 GLI2

9.67e-04101392cv:C0079541
DiseaseX-23974 measurement

UGT1A5 UGT1A3

9.67e-04101392EFO_0800867
Diseasehistidine betaine (hercynine) measurement

UGT1A5 UGT1A3

1.18e-03111392EFO_0800972
DiseaseX-21796 measurement

UGT1A5 UGT1A3

1.18e-03111392EFO_0800825
Diseaseinsomnia, bilirubin measurement

UGT1A5 UGT1A3

1.18e-03111392EFO_0004570, EFO_0004698
Diseasealdosterone measurement

UGT1A5 UGT1A3

1.18e-03111392EFO_0010219
Diseasep-cresol glucuronide measurement

UGT1A5 UGT1A3

1.41e-03121392EFO_0800079
Diseasebiliverdin measurement

UGT1A5 UGT1A3

1.41e-03121392EFO_0021033
Diseasecomplement factor H-related protein 4 measurement

CFHR1 SGPP2 CNKSR2

1.61e-03491393EFO_0600091
Diseaseretinol dehydrogenase 16 measurement

UGT1A5 UGT1A3

1.66e-03131392EFO_0802007
Diseasewaist-hip ratio

FOXO3 RBMS1 HECTD4 BCL6 ABLIM3 PTGR3 CFAP65 SLC35F5 TAOK2 PIAS4 ZNRF3 RAPGEF3 ZMYM4 PHLDB2

1.99e-03122613914EFO_0004343
Diseaseurate measurement, spine bone mineral density

UGT1A5 UGT1A3 SLC8A1

2.61e-03581393EFO_0004531, EFO_0007701
Diseaselow density lipoprotein cholesterol measurement, body fat percentage

UGT1A5 UGT1A3

2.86e-03171392EFO_0004611, EFO_0007800
Diseaseangiopoietin-related protein 1 measurement

UGT1A5 UGT1A3

3.21e-03181392EFO_0801382
Diseasetea consumption measurement

MGAM TUBG2 HECTD4 SLC8A1

3.29e-031291394EFO_0010091
Diseasetemporal lobe epilepsy (is_marker_for)

FOXO3 RELN

3.96e-03201392DOID:3328 (is_marker_for)
Diseasetissue factor measurement

UGT1A5 UGT1A3

4.36e-03211392EFO_0010623

Protein segments in the cluster

PeptideGeneStartEntry
SSYIPRLLTTNSDHM

UGT1A3

191

P35503
ILEMHPFLSLGTSRT

AGXT2

21

Q9BYV1
LSHSSGAVRYLMHVP

FAM234A

321

Q9H0X4
LASHSMLPSDVSILY

ERICH1

376

Q86X53
EMSLNGSPRSHYLAD

ABLIM3

561

O94929
MASLYTSHPADNGLT

CCDC186

831

Q7Z3E2
SSVPYLHLHSRQGSM

ASH1L

1131

Q9NR48
SGYSISSFLQMLHPE

DISP3

1076

Q9P2K9
RNLMYLVSPSSEHLG

ATG14

376

Q6ZNE5
TPDLVGMLLSYSHSE

ARHGEF5

616

Q12774
PHRDSLYTSMPTLAG

ADGRL3

1351

Q9HAR2
RHMALSRTPTPSDSY

AJM1

231

C9J069
SHMSLPATRGYALTA

AP1G2

516

O75843
TSLPTSHTYLGADME

CRBN

51

Q96SW2
LGGTETEYSLLHMPS

GCSAM

121

Q8N6F7
RSSYALRPHFMLISS

ECT2L

281

Q008S8
ERTPTHYHMLLSSAG

ASMT

311

P46597
VTEHRMGPGLSLISY

CD177

86

Q8N6Q3
EVHYRSLSLKPSEGM

ADCY10

891

Q96PN6
YLHLLVTMSTPRGVF

CCDC87

131

Q9NVE4
TGTTALYLFLVMHPS

NDST3

606

O95803
RLAGMTLTYDPTTAA

RBMS1

251

P29558
HLSLSSTGTYMPTAA

RBMS2

346

Q15434
TMLSSGSGPVLLRSY

RFT1

361

Q96AA3
YIRTSLSPGSGMVTH

IREB2

541

P48200
ILATISDSHLHTPMY

OR7A5

46

Q15622
LDMGRLHRPRSSTSY

PCDH20

26

Q8N6Y1
ITLIGLSSHLHTPMY

OR8G5

81

Q8NG78
PHVRSSSEIYGLMKA

GK3P

231

Q14409
ASRMESTGLPYRIHV

GUCY2D

1006

Q02846
GHLVTTVTLRLPSYM

INMT

191

O95050
LIASPRGSKSYLSHM

NLRP8

541

Q86W28
TTHYMLRLVGVGLTS

CFAP65

976

Q6ZU64
YMPHLESRDRGLSSK

MGAM

1446

O43451
LTGTARYMSINTHLG

CSNK1G1

211

Q9HCP0
HMSIYSGLTSKVRPA

FRMD7

456

Q6ZUT3
LAPAGMINSHSYSSR

GPR137C

331

Q8N3F9
SILTTTGYGHMAPLS

KCNK7

101

Q9Y2U2
DMTTPLGLSRQHLSY

LMTK3

121

Q96Q04
LPGRLYSSMSDTNLA

BSN

1976

Q9UPA5
MVYRLLGHVFPSTHT

FSIP2

5121

Q5CZC0
DHAPAIGRYIRTLMS

ECPAS

621

Q5VYK3
TIMVATLGPASHSYD

KIF3C

336

O14782
YHLSRQSSDPSVLMS

PCNX2

1046

A6NKB5
SHSMSASLEPFLYGL

PCNX3

1596

Q9H6A9
TLRVLYTPGHTDDHM

LACTB2

136

Q53H82
SDTSLHSPMYFLLGN

OR4K5

51

Q8NGD3
MSPRVLTGLLLSSYA

OR4K13

136

Q8NH42
ILTVTSDSRLHTPMY

OR4K15

46

Q8NH41
MAKESTQGHRSYLLP

EEF2KMT

101

Q96G04
RTMTSLYGSIHPADS

DCAF10

146

Q5QP82
LSALSQTSYHDPIMG

FRYL

1891

O94915
GSDNSIPMAYLTLDH

MAP3K7

491

O43318
LIASMSSDSLRHVYG

F13A1

706

P00488
RYELSLHPNLTSMTF

LNPEP

176

Q9UIQ6
LHSYMDAHSPTTLGL

LHX8

326

Q68G74
MEHYLRSVHSSPTLS

GLI2

126

P10070
TGDPYMRSLVQHILS

TUBGCP3

406

Q96CW5
ELRQTPMYTHSIAAL

HECTD4

3536

Q9Y4D8
GAVLFMYLRPTAHSS

OR6X1

251

Q8NH79
TLGYPAMHLPRSSFS

OSR1

56

Q8TAX0
TAPVLLQYSHDAGMS

RELN

1316

P78509
ILAISIDSRLHTPMY

OR1F2P

46

Q96R84
KDHPRQGSILYSMLT

NR0B1

71

P51843
IIMHSSVYSSPAAAG

ADCYAP1

16

P18509
STLGYRMVHPSLLKS

CCSER2

311

Q9H7U1
MDLVLDSSGVHYSTP

DNAH1

661

Q9P2D7
YHEPSSIGSMALTES

FAM126A

136

Q9BYI3
APMLKAREYHSSSVL

KLHL21

366

Q9UJP4
GTIRSHASASLYLLM

DOCK7

1566

Q96N67
SRMESTGLPYRIHVS

GUCY2F

1011

P51841
IDTTRMGYRPIAIHS

DNAH7

3196

Q8WXX0
SMYSHLPVSSLLFSD

BCL6

196

P41182
PGTEVTYRLQLHMLS

IL12RB1

276

P42701
AHSLALVTVPSMGYA

MAN2C1

646

Q9NTJ4
DIRMGTLKRLSPHYT

MASP2

496

O00187
SLTTLTRYPDSMLGA

KCTD6

26

Q8NC69
YVMATHGILSAEAPR

PRPSAP1

281

Q14558
GRSLPAGSLISMHIY

CYP4B1

396

P13584
ASATMHLPATIGDYT

FAH

111

P16930
AHILSRQMSKYPSGE

CFHR1

156

Q03591
SLSSLNMGTLPRSLY

GRIP1

416

Q9Y3R0
LLVPAMYSSDTRGSL

CREB3

241

O43889
PASYSLAGTQHMEAL

SLFN13

536

Q68D06
SISSLSELVRAMHPY

PPRC1

301

Q5VV67
GLISLDSRLHTPMYF

OR2A1;

46

Q8NGT9
GLISLDSRLHTPMYF

OR2A25

46

A4D2G3
LLLYHSTMSSKSPRD

NUMA1

101

Q14980
ILTISSDSHLHTPMY

OR7C2

46

O60412
TMPAGLIYASVSVHA

APOOL

11

Q6UXV4
YLMRELPGSTELTGS

MED19

66

A0JLT2
SSSMPYLALAHNRVS

OBSCN-AS1

21

Q96MR7
ALGLAHSTDPSALMY

MMP20

231

O60882
ISRPLHYTTIMSPRS

OR1A1

126

Q9P1Q5
THMLSPLIYTLRNSE

OR4A5

276

Q8NH83
ITLIGLSSHLHTPMY

OR8G3P

46

P0DMU2
SLYSTSANLPVMGHE

FOXO3

591

O43524
LYRRHSFMSTEPLSA

RUNDC3A

361

Q59EK9
TLMHRDSYPRFLSSP

RGS19

186

P49795
LDYTQTSDPGRHVML

RMDN3

51

Q96TC7
SSAISPHGRYIASIM

TBC1D31

311

Q96DN5
PSSHALEAKLSRMSY

SLC35F5

206

Q8WV83
YLLSHPSDSLELMVS

LILRA1

406

O75019
LAHYSSLVRVLGSDM

NBR1

111

Q14596
SLLNIYSPLLSHMSS

PLAC8L1

16

A1L4L8
ILATISDSHLHTPMY

OR7A10

46

O76100
FHSTLRHDRPYTLSM

PPWD1

566

Q96BP3
PASYSLAGTQHMEAL

SLFN11

536

Q7Z7L1
EPYMHRAGTLTSLES

TAOK2

336

Q9UL54
ILATISDSHLHTPMY

OR7A17

46

O14581
TMLTEYHPLGSLSNL

POMK

146

Q9H5K3
GLHASYLAMSTPLSP

HERC2P3

41

Q9BVR0
LSHMGAYSRSLPRLY

PHLDB2

246

Q86SQ0
IEMALLSLGYSHSSA

SATB1

111

Q01826
SRLYTGMHTVLDVLG

SGPP2

206

Q8IWX5
HMKTLRGATNPYTEA

ARNTL

121

O00327
AHTGDPDLTLSYLSM

CINP

171

Q9BW66
LSPLGEHRISTKMEY

CNKSR2

921

Q8WXI2
MTAPGTRRHIYDTKL

CNN2

221

Q99439
TRPHSLMIYSDDLGV

NEU3

196

Q9UQ49
GIRSAMRYLTSHLTP

TEX44

371

Q53QW1
YGSMLHTDPVATSFL

RAPGEF3

476

O95398
LSRHLMSHTGESPYE

ZNF2

216

Q9BSG1
LSPSGIRLSDEYMGT

TIAM2

311

Q8IVF5
LHFLMTGYTPLTTDQ

TUBG1

266

P23258
MGLITHTDSPYIRAL

PRPF38B

146

Q5VTL8
MASESSPLLAYRLLG

SLC12A9

1

Q9BXP2
SSYIPRLLTTNSDHM

UGT1A5

191

P35504
DGPVYSMVSTDRHLL

THOC6

76

Q86W42
YLGSARSLSPHKMAD

SORBS3

331

O60504
SYAPRHVTLTTLMDT

SIGLEC1

981

Q9BZZ2
LDPLTMHSTYDRAGA

PIAS4

81

Q8N2W9
PTGSMLLNSTSHLDY

SAXO2

241

Q658L1
PTGARAIVDMSYARH

PTGR3

6

Q8N4Q0
ALSSSIYLLREMGPT

ZSWIM2

26

Q8NEG5
RYGLVMTEAHLPSQT

WASHC4

761

Q2M389
LLTMDRHGEQSLYSP

ZNRF3

396

Q9ULT6
FPTSHSVLYMRGRLA

TTC7A

741

Q9ULT0
PFHMLLLLSRTYESS

TGM1

146

P22735
LHFLMTGYTPLTTDQ

TUBG2

266

Q9NRH3
LPRLLVASSSGHLYM

WIPI1

326

Q5MNZ9
LTISTVGGSHYLLMD

UGT3A2

26

Q3SY77
LSYVPVFRSLLTDHM

UGT3A2

181

Q3SY77
IYPSALRIHMRTHTG

ZNF699

541

Q32M78
MTSSYGHVLERQPAL

PRRX1

1

P54821
IMSTSLRVSPSIHGY

TCIM

11

Q9NR00
TAEIYTLAAMHRPGT

HIVEP2

1701

P31629
EGSPVLLRSSMHYSL

WDR87

716

Q6ZQQ6
LASRAGHTLPRVMVY

PRRG3

121

Q9BZD7
IDHNLTPTLDSMSYG

ZMYM4

41

Q5VZL5
RNHSLEPLSTFLTYM

ATP6V0D2

86

Q8N8Y2
GEPMLVARYSHRSTA

KLHL38

366

Q2WGJ6
MHAQRTSGSSAPTLY

LYPD6B

156

Q8NI32
RLSLSPTFSMGFHLL

SLC8A1

6

P32418
TPVLYAMLDHSRSTK

MPZ

216

P25189
RGYTTIHDTPMLLHV

NEB

5486

P20929