Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	testosterone 6-beta-hydroxylase activity	CYP3A7 CYP3A5	2.81e-05	5	34	2	GO:0050649
GeneOntologyMolecularFunction	estrogen 2-hydroxylase activity	CYP3A7 CYP3A5	7.83e-05	8	34	2	GO:0101021
GeneOntologyMolecularFunction	estrogen 16-alpha-hydroxylase activity	CYP3A7 CYP3A5	1.53e-04	11	34	2	GO:0101020
GeneOntologyMolecularFunction	retinoic acid 4-hydroxylase activity	CYP3A7 CYP3A5	2.53e-04	14	34	2	GO:0008401
GeneOntologyMolecularFunction	sialic acid binding	ST8SIA3 FCN1	8.24e-04	25	34	2	GO:0033691
GeneOntologyMolecularFunction	polysaccharide binding	ENDOU FCN1	1.27e-03	31	34	2	GO:0030247
GeneOntologyMolecularFunction	steroid hydroxylase activity	CYP3A7 CYP3A5	1.53e-03	34	34	2	GO:0008395
GeneOntologyMolecularFunction	aromatase activity	CYP3A7 CYP3A5	1.62e-03	35	34	2	GO:0070330
GeneOntologyMolecularFunction	oxygen binding	CYP3A7 CYP3A5	1.81e-03	37	34	2	GO:0019825
Domain	DUF1897	FUBP1 KHSRP	3.41e-06	2	35	2	PF09005
Domain	DUF1897	FUBP1 KHSRP	3.41e-06	2	35	2	IPR015096
Domain	Cyt_P450_E_grp-II	CYP3A7 CYP3A5	3.40e-05	5	35	2	IPR002402
Domain	Cyt_P450_E_CYP3A	CYP3A7 CYP3A5	5.09e-05	6	35	2	IPR008072
Domain	ELM2	RERE ZNF541	2.63e-04	13	35	2	SM01189
Domain	ELM2	RERE ZNF541	2.63e-04	13	35	2	PF01448
Domain	ELM2	RERE ZNF541	2.63e-04	13	35	2	PS51156
Domain	ELM2_dom	RERE ZNF541	2.63e-04	13	35	2	IPR000949
Domain	-	TTC39B PSMD11 SEL1L2 TTC21A	5.86e-04	207	35	4	1.25.40.10
Domain	TPR-like_helical_dom	TTC39B PSMD11 SEL1L2 TTC21A	9.12e-04	233	35	4	IPR011990
Domain	SANT_dom	RERE ZNF541	1.08e-03	26	35	2	IPR017884
Domain	SANT	RERE ZNF541	1.25e-03	28	35	2	PS51293
Domain	Myb_DNA-binding	RERE ZNF541	1.95e-03	35	35	2	PF00249
Domain	KH_1	FUBP1 KHSRP	2.30e-03	38	35	2	PF00013
Domain	MYB_LIKE	RERE ZNF541	2.30e-03	38	35	2	PS50090
Domain	-	FUBP1 KHSRP	2.42e-03	39	35	2	3.30.1370.10
Domain	KH	FUBP1 KHSRP	2.54e-03	40	35	2	SM00322
Domain	KH_dom	FUBP1 KHSRP	2.54e-03	40	35	2	IPR004087
Domain	KH_TYPE_1	FUBP1 KHSRP	2.80e-03	42	35	2	PS50084
Domain	KH_dom_type_1	FUBP1 KHSRP	3.07e-03	44	35	2	IPR004088
Domain	Cyt_P450_E_grp-I	CYP3A7 CYP3A5	3.21e-03	45	35	2	IPR002401
Domain	SANT	RERE ZNF541	3.95e-03	50	35	2	SM00717
Domain	SANT/Myb	RERE ZNF541	4.27e-03	52	35	2	IPR001005
Domain	Cyt_P450_CS	CYP3A7 CYP3A5	4.43e-03	53	35	2	IPR017972
Domain	TPR_8	TTC39B TTC21A	4.43e-03	53	35	2	PF13181
Domain	CYTOCHROME_P450	CYP3A7 CYP3A5	5.10e-03	57	35	2	PS00086
Domain	p450	CYP3A7 CYP3A5	5.28e-03	58	35	2	PF00067
Domain	Cyt_P450	CYP3A7 CYP3A5	5.64e-03	60	35	2	IPR001128
Pubmed	Overexpression of far upstream element binding proteins: a mechanism regulating proliferation and migration in liver cancer cells.	FUBP1 KHSRP	9.84e-07	2	35	2	19585652
Pubmed	2-D DIGE profiling of hepatocellular carcinoma tissues identified isoforms of far upstream binding protein (FUBP) as novel candidates in liver carcinogenesis.	FUBP1 KHSRP	9.84e-07	2	35	2	19003864
Pubmed	FUBP1 and FUBP2 enforce distinct epigenetic setpoints for MYC expression in primary single murine cells.	FUBP1 KHSRP	9.84e-07	2	35	2	33005010
Pubmed	CYP3A gene expression in human gut epithelium.	CYP3A7 CYP3A5	9.84e-07	2	35	2	7894497
Pubmed	CYP3A genes and the association between prenatal methylmercury exposure and neurodevelopment.	CYP3A7 CYP3A5	9.84e-07	2	35	2	28500872
Pubmed	Expression of CYP3A4, CYP3A5 and CYP3A7 in human duodenal tissue.	CYP3A7 CYP3A5	9.84e-07	2	35	2	8877031
Pubmed	PLK1 depletion alters homologous recombination and synaptonemal complex disassembly events during mammalian spermatogenesis.	PLK1 EDIL3	2.95e-06	3	35	2	35274968
Pubmed	Comparison of steroid hormone hydroxylation mediated by cytochrome P450 3A subfamilies.	CYP3A7 CYP3A5	2.95e-06	3	35	2	32001245
Pubmed	CYP3A Polymorphism and Chronic Mercury Intoxication.	CYP3A7 CYP3A5	2.95e-06	3	35	2	32146629
Pubmed	The P450 oxidoreductase genotype is associated with CYP3A activity in vivo as measured by the midazolam phenotyping test.	CYP3A7 CYP3A5	2.95e-06	3	35	2	19801957
Pubmed	The far upstream element-binding proteins comprise an ancient family of single-strand DNA-binding transactivators.	FUBP1 KHSRP	2.95e-06	3	35	2	8940189
Pubmed	Isolation of a promoter region in mouse cytochrome P450 3A (Cyp3A16) gene and its transcriptional control.	MMP15 CYP3A5	2.95e-06	3	35	2	9048885
Pubmed	Metabolic pathways of inhaled glucocorticoids by the CYP3A enzymes.	CYP3A7 CYP3A5	2.95e-06	3	35	2	23143891
Pubmed	Development of template systems for ligand interactions of CYP3A5 and CYP3A7 and their distinctions from CYP3A4 template.	CYP3A7 CYP3A5	2.95e-06	3	35	2	33866277
Pubmed	Cytochrome P450 3A gene variation, steroid hormone serum levels and prostate cancer--The Rotterdam Study.	CYP3A7 CYP3A5	2.95e-06	3	35	2	20621111
Pubmed	Sequence of the 5'-flanking region of CYP3A5: comparative analysis with CYP3A4 and CYP3A7.	CYP3A7 CYP3A5	2.95e-06	3	35	2	7811260
Pubmed	PLK1 is required for chromosome compaction and microtubule organization in mouse oocytes.	PLK1 EDIL3	2.95e-06	3	35	2	32267211
Pubmed	Differences in CYP3A41G genotype distribution and haplotypes of CYP3A4, CYP3A5 and CYP3A7 in 3 Chinese populations.	CYP3A7 CYP3A5	2.95e-06	3	35	2	17582393
Pubmed	Contribution of three CYP3A isoforms to metabolism of R- and S-warfarin.	CYP3A7 CYP3A5	2.95e-06	3	35	2	20615193
Pubmed	Cytochrome P450 3As gene expression and testosterone 6 beta-hydroxylase activity in human fetal membranes and placenta at full term.	CYP3A7 CYP3A5	2.95e-06	3	35	2	20118548
Pubmed	CYP3A7, CYP3A4, and CYP3A5 genetic polymorphisms in recipients rather than donors influence tacrolimus concentrations in the early stages after liver transplantation.	CYP3A7 CYP3A5	2.95e-06	3	35	2	34688813
Pubmed	CYP1A1, CYP3A5 and CYP3A7 polymorphisms and testicular cancer susceptibility.	CYP3A7 CYP3A5	2.95e-06	3	35	2	20345875
Pubmed	Detection of cytochrome P450 gene expression in human placenta in first trimester of pregnancy.	CYP3A7 CYP3A5	5.90e-06	4	35	2	8694864
Pubmed	CYP3A7, CYP3A5, CYP3A4, and ABCB1 genetic polymorphisms, cyclosporine concentration, and dose requirement in transplant recipients.	CYP3A7 CYP3A5	5.90e-06	4	35	2	18978522
Pubmed	1199G>A and 2677G>T/A polymorphisms of ABCB1 independently affect tacrolimus concentration in hepatic tissue after liver transplantation.	CYP3A7 CYP3A5	5.90e-06	4	35	2	17885626
Pubmed	Allele and genotype frequencies of CYP3A4, CYP3A5, CYP3A7, and GSTP1 gene polymorphisms among mainland Tibetan, Mongolian, Uyghur, and Han Chinese populations.	CYP3A7 CYP3A5	5.90e-06	4	35	2	34689350
Pubmed	Cytochrome P450 isoforms are differently up-regulated in aflatoxin B₁-exposed human lymphocytes and monocytes.	CYP3A7 CYP3A5	9.82e-06	5	35	2	24168324
Pubmed	Human cytochrome P450 3A7 has a distinct high catalytic activity for the 16alpha-hydroxylation of estrone but not 17beta-estradiol.	CYP3A7 CYP3A5	9.82e-06	5	35	2	14559847
Pubmed	Genomic organization of the human CYP3A locus: identification of a new, inducible CYP3A gene.	CYP3A7 CYP3A5	9.82e-06	5	35	2	11266076
Pubmed	Identification of human cytochrome P450s involved in the formation of all-trans-retinoic acid principal metabolites.	CYP3A7 CYP3A5	9.82e-06	5	35	2	11093772
Pubmed	The human cytochrome P450 3A locus. Gene evolution by capture of downstream exons.	CYP3A7 CYP3A5	2.06e-05	7	35	2	11137287
Pubmed	Cooperative assembly of an hnRNP complex induced by a tissue-specific homolog of polypyrimidine tract binding protein.	FUBP1 KHSRP	2.06e-05	7	35	2	11003644
Pubmed	Association between ABCC2 polymorphism and lopinavir accumulation in peripheral blood mononuclear cells of HIV-infected patients.	CYP3A7 CYP3A5	2.06e-05	7	35	2	19842932
Pubmed	Isolation, characterization, and mapping of two mouse mitochondrial voltage-dependent anion channel isoforms.	VDAC2 GABRA6	2.06e-05	7	35	2	8660977
Pubmed	ABCB1 and cytochrome P450 polymorphisms: clinical pharmacogenetics of clozapine.	CYP3A7 CYP3A5	2.74e-05	8	35	2	19593168
Pubmed	A phenotype-genotype approach to predicting CYP450 and P-glycoprotein drug interactions with the mixed inhibitor/inducer tipranavir/ritonavir.	CYP3A7 CYP3A5	2.74e-05	8	35	2	20147896
Pubmed	Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.	RERE SLF1 PLK1 CYP3A5 PPIL3 VDAC2 TM9SF3 KHSRP	4.12e-05	1327	35	8	32694731
Pubmed	Characterization of the oxidative metabolites of 17beta-estradiol and estrone formed by 15 selectively expressed human cytochrome p450 isoforms.	CYP3A7 CYP3A5	4.40e-05	10	35	2	12865317
Pubmed	Conditional mutation of Smc5 in mouse embryonic stem cells perturbs condensin localization and mitotic progression.	PLK1 EDIL3	5.38e-05	11	35	2	26919979
Pubmed	CYP2B6, CYP3A4, and CYP2C19 are responsible for the in vitro N-demethylation of meperidine in human liver microsomes.	CYP3A7 CYP3A5	6.45e-05	12	35	2	15319333
Pubmed	Sequence diversity and haplotype structure at the human CYP3A cluster.	CYP3A7 CYP3A5	7.62e-05	13	35	2	16314882
Pubmed	Dystroglycan organizes axon guidance cue localization and axonal pathfinding.	EDIL3 GABRA6	8.89e-05	14	35	2	23217742
Pubmed	HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.	TTC39B PLK1 FUBP1 VDAC2 KHSRP MOB2	9.66e-05	754	35	6	35906200
Pubmed	Proteomic analysis reveals that MAEL, a component of nuage, interacts with stress granule proteins in cancer cells.	FUBP1 KHSRP	1.02e-04	15	35	2	24189637
Pubmed	Genetic polymorphisms in phase I and phase II enzymes and breast cancer risk associated with menopausal hormone therapy in postmenopausal women.	CYP3A7 CYP3A5	1.33e-04	17	35	2	19424794
Pubmed	Genes, plasticity and mental retardation.	GRIA3 OPHN1	1.66e-04	19	35	2	18329113
Pubmed	Molecular genetics of the human cytochrome P450 monooxygenase superfamily.	CYP3A7 CYP3A5	1.85e-04	20	35	2	9890157
Pubmed	NSP6 inhibits the production of ACE2-containing exosomes to promote SARS-CoV-2 infectivity.	PSMD11 VDAC2	2.24e-04	22	35	2	38303107
Pubmed	Inhibition of SAPK2a/p38 prevents hnRNP A0 phosphorylation by MAPKAP-K2 and its interaction with cytokine mRNAs.	FUBP1 KHSRP	2.24e-04	22	35	2	12456657
Pubmed	Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.	PSMD11 EDIL3 MICOS13 FUBP1 OPHN1 MOB2	2.77e-04	916	35	6	32203420
Pubmed	Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.	PLK1 MICOS13 FUBP1 KHSRP	3.74e-04	341	35	4	32971831
Pubmed	In silico APC/C substrate discovery reveals cell cycle-dependent degradation of UHRF1 and other chromatin regulators.	TTC39B PSMD11 PLK1 CEBPZ VDAC2 KHSRP	3.79e-04	971	35	6	33306668
Pubmed	Targeted inactivation of murine Ddx3x: essential roles of Ddx3x in placentation and embryogenesis.	PLK1 EDIL3	4.20e-04	30	35	2	27179789
Pubmed	Evaluation of candidate genes for cholinesterase activity in farmworkers exposed to organophosphorus pesticides: association of single nucleotide polymorphisms in BCHE.	CYP3A7 CYP3A5	4.20e-04	30	35	2	20529763
Pubmed	Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.	PSMD11 C5 PHPT1 MMP15 MICOS13 TM9SF3	6.05e-04	1061	35	6	33845483
Pubmed	An important role for CDK2 in G1 to S checkpoint activation and DNA damage response in human embryonic stem cells.	PSMD11 FUBP1 VDAC2 KHSRP	6.62e-04	397	35	4	21319273
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	PSMD11 PLK1 FUBP1 PPIL3 TM9SF3 KHSRP	7.41e-04	1103	35	6	34189442
Pubmed	TIF1γ inhibits lung adenocarcinoma EMT and metastasis by interacting with the TAF15/TBP complex.	FUBP1 VDAC2 KHSRP	7.77e-04	179	35	3	36261009
GeneFamily	Cytochrome P450 family 3	CYP3A7 CYP3A5	5.54e-05	8	26	2	1002
GeneFamily	GATA zinc finger domain containing\|Myb/SANT domain containing	RERE ZNF541	2.62e-03	53	26	2	532
GeneFamily	X-linked mental retardation\|Angiotensin receptors	GRIA3 OPHN1	2.62e-03	53	26	2	103
GeneFamily	Tetratricopeptide repeat domain containing\|Bardet-Biedl syndrome associated\|BBSome	TTC39B TTC21A	1.18e-02	115	26	2	769
Computational	Neighborhood of RFC4	CEBPZ STK24 VDAC2 KHSRP	2.25e-04	151	22	4	MORF_RFC4
Computational	Neighborhood of BUB1B	PLK1 CEBPZ KHSRP	3.13e-04	66	22	3	MORF_BUB1B
Drug	Delcorine; Up 200; 8.4uM; MCF7; HT_HG-U133A	CYP3A7 PSMD11 RERE EDIL3 CYP3A5 KHSRP	4.82e-07	195	35	6	3613_UP
Drug	pentachlorophenol	CYP3A7 C5 EDIL3 CYP3A5	3.39e-05	120	35	4	CID000000992
Drug	Alfentanil	CYP3A7 CYP3A5	3.43e-05	6	35	2	ctd:D015760
Drug	NSC 46286	RERE CYP3A5	4.80e-05	7	35	2	CID000006881
Drug	triazolam	CYP3A7 CYP3A5 GABRA6	7.82e-05	54	35	3	CID000005556
Drug	S 840	CYP3A7 CYP3A5	8.21e-05	9	35	2	CID000096338
Drug	indiplon	CYP3A7 EDIL3 GABRA6	9.20e-05	57	35	3	CID006450813
Drug	4-hydroxymidazolam	CYP3A7 CYP3A5	1.03e-04	10	35	2	CID000124449
Drug	N-isopropyl-p-iodoamphetamine	RERE CEBPZ	1.25e-04	11	35	2	CID000003729
Drug	Ticalopride	CYP3A7 CYP3A5	1.25e-04	11	35	2	CID000216236
Drug	Troleandomycin	CYP3A7 CYP3A5	1.25e-04	11	35	2	ctd:D014217
Drug	enflurane	GRIA3 CYP3A5 GABRA6	1.56e-04	68	35	3	CID000003226
Drug	taxol	CYP3A7 PHPT1 PLK1 CYP3A5 TAF1A VDAC2	1.91e-04	560	35	6	CID000004666
Drug	17-DMAG; Down 200; 0.1uM; PC3; HT_HG-U133A	RERE EDIL3 TBC1D8B STK24	2.05e-04	191	35	4	4437_DN
Drug	propionanilide	CYP3A7 CYP3A5	2.07e-04	14	35	2	CID000012107
Drug	7-BFC	CYP3A7 CYP3A5	2.07e-04	14	35	2	CID000848780
Drug	tetrachlorophenol	C5 CYP3A5	2.07e-04	14	35	2	CID000021013
Drug	Quinethazone [73-49-4]; Down 200; 13.8uM; PC3; HT_HG-U133A	RERE EDIL3 TBC1D8B CYP3A5	2.18e-04	194	35	4	4529_DN
Drug	Sulfamethoxazole [723-46-6]; Up 200; 15.8uM; HL60; HT_HG-U133A	GRIA3 C5 CYP3A5 FCN1	2.26e-04	196	35	4	2335_UP
Drug	Mimosine [500-44-7]; Up 200; 20.2uM; PC3; HT_HG-U133A	GRIA3 EDIL3 ST8SIA3 FUBP1	2.31e-04	197	35	4	6703_UP
Drug	Boldine [476-70-0]; Up 200; 12.2uM; PC3; HT_HG-U133A	GRIA3 ST8SIA3 CYP3A5 FUBP1	2.31e-04	197	35	4	4004_UP
Drug	Cyanocobalamin [68-19-9]; Up 200; 3uM; MCF7; HT_HG-U133A	RERE CYP3A5 FCN1 STK24	2.35e-04	198	35	4	4395_UP
Drug	Atropine sulfate monohydrate [5908-99-6]; Up 200; 5.8uM; PC3; HT_HG-U133A	GRIA3 EDIL3 ST8SIA3 KHSRP	2.35e-04	198	35	4	5865_UP
Drug	SC-560; Down 200; 10uM; PC3; HT_HG-U133A	TBC1D8B ST8SIA3 STK24 KHSRP	2.35e-04	198	35	4	6865_DN
Drug	(S)-(-)-Cycloserine [339-72-0]; Down 200; 39.2uM; MCF7; HT_HG-U133A	RERE MMP15 ZNF551 KHSRP	2.40e-04	199	35	4	4346_DN
Drug	Phentolamine hydrochloride [73-05-2]; Down 200; 12.6uM; MCF7; HT_HG-U133A	PSMD11 C5 RERE KHSRP	2.40e-04	199	35	4	3860_DN
Drug	Scopolamin-N-oxide hydrobromide [6106-81-6]; Up 200; 10uM; MCF7; HT_HG-U133A	GRIA3 FCN1 STK24 ZNF551	2.40e-04	199	35	4	5436_UP
Drug	pH Q	CYP3A7 CYP3A5 GABRA6	2.43e-04	79	35	3	CID000007708
Drug	CP-944629 [668990-94-1]; Down 200; 10uM; MCF7; HT_HG-U133A	RERE CEBPZ TAF1A ZNF551	2.44e-04	200	35	4	7544_DN
Drug	noralfentanil	CYP3A7 CYP3A5	3.08e-04	17	35	2	CID000162172
Drug	purpurogallin	PLK1 CYP3A5	3.08e-04	17	35	2	CID005281571
Drug	aflatoxin	CYP3A7 CYP3A5	3.46e-04	18	35	2	CID000014421
Drug	pleuromutilin	CYP3A7 CYP3A5	3.46e-04	18	35	2	CID000031326
Drug	Azamulinum	CYP3A7 CYP3A5	3.46e-04	18	35	2	CID003086060
Drug	Fenthion	CYP3A7 CYP3A5	3.46e-04	18	35	2	ctd:D005284
Drug	AC1L1SX8	CYP3A7 CYP3A5	3.46e-04	18	35	2	CID000060278
Drug	rabeprazole	CYP3A7 CYP3A5	3.86e-04	19	35	2	CID000005029
Drug	benzimidazole	CYP3A7 PLK1 CYP3A5	3.93e-04	93	35	3	CID000005798
Drug	CID5475388	CYP3A7 CYP3A5	4.29e-04	20	35	2	CID005475388
Drug	bromobenzene	CYP3A7 CYP3A5 PDCD1LG2	4.44e-04	97	35	3	CID000007961
Drug	coma I	CYP3A5 TAF1A	4.73e-04	21	35	2	CID009578275
Drug	Iomazenil (123I	RERE GABRA6	5.20e-04	22	35	2	CID000065959
Drug	Ai-a	CYP3A7 C5 CYP3A5	5.30e-04	103	35	3	CID000053040
Drug	pyridoxamine	PHPT1 PLK1 GABRA6	5.60e-04	105	35	3	CID000001052
Drug	pentanol	GRIA3 CYP3A5	5.69e-04	23	35	2	CID000006276
Drug	midazolam	CYP3A7 CYP3A5 GABRA6	5.92e-04	107	35	3	CID000004192
Drug	5-hydroxythalidomide	CYP3A7 CYP3A5	6.20e-04	24	35	2	ctd:C544471
Drug	fenthion	CYP3A7 CYP3A5	6.20e-04	24	35	2	CID000003346
Drug	Midazolam	CYP3A5 GABRA6	6.74e-04	25	35	2	ctd:D008874
Drug	PD 0325901	CYP3A7 CYP3A5 PDCD1LG2	7.12e-04	114	35	3	ctd:C506614
Drug	1,4-naphthoquinone	CYP3A7 CYP3A5	7.29e-04	26	35	2	ctd:C035342
Drug	C14845	CYP3A7 CYP3A5	7.87e-04	27	35	2	CID011954064
Drug	BP-9,10-oxide	CYP3A7 CYP3A5	7.87e-04	27	35	2	CID000037456
Drug	Brn 4136738	CYP3A7 CYP3A5	7.87e-04	27	35	2	CID000050331
Drug	16alpha-hydroxyestrone	CYP3A7 CYP3A5	7.87e-04	27	35	2	CID000114852
Drug	9-OH-BaP-4,5-oxide	CYP3A7 CYP3A5	8.46e-04	28	35	2	CID000115064
Drug	mephobarbital	CYP3A5 GABRA6	8.46e-04	28	35	2	CID000008271
Drug	isopropanol	RERE CYP3A5 VDAC2	8.67e-04	122	35	3	CID000003776
Drug	SR-12813	CYP3A7 CYP3A5	9.08e-04	29	35	2	CID000446313
Drug	tofisopam	EDIL3 GABRA6	9.08e-04	29	35	2	CID000005502
Drug	3,4-dioctylphthalic acid	GRIA3 CYP3A7 CYP3A5	9.52e-04	126	35	3	CID005743034
Drug	11-H-14,15-EETA	CYP3A7 CYP3A5	9.72e-04	30	35	2	CID011954058
Drug	19-hydroxytestosterone	CYP3A7 CYP3A5	9.72e-04	30	35	2	CID000150968
Drug	piptal	C5 CYP3A5	9.72e-04	30	35	2	CID000031322
Drug	3-isothujone	CYP3A5 GABRA6	9.72e-04	30	35	2	CID000011027
Drug	hexobarbital	CYP3A7 CYP3A5 GABRA6	9.74e-04	127	35	3	CID000003608
Drug	p-chlorophenoxyacetic acid	C5 CYP3A5	1.04e-03	31	35	2	CID000026229
Drug	BP-7,8-oxide	CYP3A7 CYP3A5	1.11e-03	32	35	2	CID000037455
Drug	SureCN1562346	CYP3A7 CYP3A5	1.18e-03	33	35	2	CID011646228
Drug	MeIQ	CYP3A7 CYP3A5	1.18e-03	33	35	2	CID000062274
Drug	1-naphthol	CYP3A7 CYP3A5	1.18e-03	33	35	2	ctd:C029350
Drug	rac-DLPC	CYP3A7 CYP3A5	1.18e-03	33	35	2	CID000065262
Drug	12(13)-EpOME	CYP3A7 CYP3A5	1.25e-03	34	35	2	CID000001416
Drug	TCEO	CYP3A7 CYP3A5	1.25e-03	34	35	2	CID000028167
Drug	temazepam	CYP3A5 GABRA6	1.25e-03	34	35	2	CID000005391
Drug	AC1L1K7W	CYP3A7 CYP3A5	1.25e-03	34	35	2	CID000005377
Drug	AC1O5XSP	CYP3A7 CYP3A5	1.25e-03	34	35	2	CID006442739
Drug	Imatinib Mesylate	CYP3A7 PLK1 CYP3A5	1.32e-03	141	35	3	ctd:D000068877
Drug	Dehydroepiandrosterone	CYP3A7 C5 CYP3A5	1.32e-03	141	35	3	ctd:D003687
Drug	AC1L1CJI	CYP3A7 CYP3A5	1.32e-03	35	35	2	CID000001929
Drug	pantoprazole	CYP3A7 CYP3A5	1.32e-03	35	35	2	CID000004679
Drug	15-H-11,12-EETA	CYP3A7 CYP3A5	1.40e-03	36	35	2	CID011954042
Drug	AC1L3NGJ	CYP3A7 CYP3A5	1.40e-03	36	35	2	CID000092121
Drug	FGIN-1-27	VDAC2 GABRA6	1.40e-03	36	35	2	CID000132496
Drug	benzocaine	CYP3A5 PDCD1LG2	1.48e-03	37	35	2	CID000002337
Drug	telithromycin	EDIL3 CYP3A5	1.48e-03	37	35	2	CID003002190
Drug	secobarbital	CYP3A5 GABRA6	1.48e-03	37	35	2	CID000005193
Disease	tacrolimus measurement	CYP3A7 CYP3A5	7.27e-06	4	33	2	EFO_0008458
Disease	ovary epithelial cancer (is_marker_for)	PLK1 FUBP1	9.39e-05	13	33	2	DOID:2152 (is_marker_for)
Disease	metabolonic lactone sulfate measurement	CYP3A7 CYP3A5	2.05e-04	19	33	2	EFO_0800659
Disease	ecosanoids measurement	CYP3A5 VDAC2	1.74e-03	55	33	2	EFO_0020044
Disease	Glioma	PLK1 FUBP1	4.28e-03	87	33	2	C0017638
Disease	Degenerative polyarthritis	EDIL3 VDAC2	4.87e-03	93	33	2	C0029408
Disease	Osteoarthrosis Deformans	EDIL3 VDAC2	4.87e-03	93	33	2	C0086743

Protein segments in the cluster

Peptide	Gene	Start	Entry
DTECYKKYGKMWGTY	CYP3A5	61	P20815
YGVAWDYKYLTLKVK	PDCD1LG2	106	Q9BQ51
GISWVKYYCQYEKET	OPHN1	281	O60890
TQYYWYDERGKKVKC	MOB2	91	Q70IA6
DYTKAWEEYYKKMGQ	FUBP1	581	Q96AE4
TYFYKGTKYWKFDNE	MMP15	526	P51511
YKWEKFVYLYDTERG	GRIA3	156	P42263
TYTWDKSTYGNGKKY	ENDOU	386	P21128
KAREYSKEGWEYVKA	MICOS13	101	Q5XKP0
SYAYPKSEIIYTWKK	GABRA6	176	Q16445
WSAAKGYKYSYKVSE	FCN1	306	O00602
YKIAYSNDGKTWAMY	EDIL3	246	O43854
YGMWTIKAKYKEDFS	C5	196	P01031
SYYEKLKRTYEIWKD	C3orf33	256	Q6P1S2
GYWTFDMECYKKYRK	CYP3A7	56	P24462
GKWYDLEYSNEYSLK	CEBPZ	181	Q03701
SDYTKAWEEYYKKIG	KHSRP	616	Q92945
IKWDKSYYSFTGFKD	TCAIM	161	Q8N3R3
KYYGSYLKDTKLWII	STK24	96	Q9Y6E0
SGIWKDYKLAFKYFY	SEL1L2	421	Q5TEA6
AYKGLLQYYTWSEKK	TAF1A	181	Q15573
EEKDWKTAYSYFYEA	PSMD11	221	O00231
YHYYDKKGTKFTTKW	ST8SIA3	336	O43173
KETGELITFYYYWKK	RERE	426	Q9P2R6
GYKWAEYHADIYDKV	PHPT1	46	Q9NRX4
YYYSDLLCKESKWSK	TTC39B	451	Q5VTQ0
KEKLVTYYSCSYWKG	TBC1D8B	156	Q0IIM8
IWGKKFEDEYSEYLK	PPIL3	66	Q9H2H8
SYYKWGEYRKASSHK	ZNF551	221	Q7Z340
TKYKWCEYGLTFTEK	VDAC2	71	P45880
YKDAVTNYKLAWKYS	TTC21A	1251	Q8NDW8
TTYEWGYKIEKDSRY	SLF1	86	Q9BQI6
ADENGEDYYLWTYKK	TM9SF3	146	Q9HD45
EDYYLWTYKKLEIGF	TM9SF3	151	Q9HD45
EYYYIWKKMIKFDCG	ZNF541	1201	Q9H0D2
VSKWVDYSDKYGLGY	PLK1	411	P53350