Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcesssomitogenesis

DMRT2 DKK1 PCDH8 PLXNA2

3.18e-0576494GO:0001756
GeneOntologyBiologicalProcesssomite development

DMRT2 DKK1 PCDH8 PLXNA2

7.32e-0594494GO:0061053
MousePhenothick apical ectodermal ridge

DKK1 GLI3

4.08e-054372MP:0001678
MousePhenoabnormal right lung accessory lobe morphology

GLI3 ADAMTS18

6.78e-055372MP:0009571
MousePhenofailure of endochondral bone ossification

NSD2 GLI3

1.42e-047372MP:0008275
MousePhenoincreased diameter of humerus

HSPG2 GLI3

1.42e-047372MP:0008160
MousePhenoabnormal endochondral bone ossification

HSPG2 NSD2 GLI3 LASP1

1.83e-04108374MP:0008272
DomainLIM

TES LASP1 FHL2 CRIP3 FHL5 CRIP2 LHX9

6.05e-1069507PF00412
Domain-

TES LASP1 FHL2 CRIP3 FHL5 CRIP2 LHX9

6.71e-10705072.10.110.10
DomainLIM_DOMAIN_2

TES LASP1 FHL2 CRIP3 FHL5 CRIP2 LHX9

7.43e-1071507PS50023
DomainZnf_LIM

TES LASP1 FHL2 CRIP3 FHL5 CRIP2 LHX9

7.43e-1071507IPR001781
DomainLIM_DOMAIN_1

TES LASP1 FHL2 CRIP3 FHL5 CRIP2 LHX9

7.43e-1071507PS00478
DomainLIM

TES LASP1 FHL2 CRIP3 FHL5 CRIP2 LHX9

7.43e-1071507SM00132
DomainIBR

RNF19A RNF144A RBCK1

6.44e-0614503PF01485
DomainIBR_dom

RNF19A RNF144A RBCK1

8.03e-0615503IPR002867
DomainDickkopf_N

DKK1 DKK2

4.20e-054502IPR006796
DomainDickkopf_N

DKK1 DKK2

4.20e-054502PF04706
DomainDM

DMRT2 DMRTA1

1.46e-047502PF00751
DomainDM_2

DMRT2 DMRTA1

1.46e-047502PS50809
DomainDM

DMRT2 DMRTA1

1.46e-047502SM00301
Domain-

DMRT2 DMRTA1

1.46e-0475024.10.1040.10
DomainDM_DNA-bd

DMRT2 DMRTA1

1.46e-047502IPR001275
DomainDM_1

DMRT2 DMRTA1

1.46e-047502PS40000
DomainRING

RNF19A NSD2 RNF144A RNF10 TRIM21 RBCK1

1.57e-04305506SM00184
DomainDMRT/dsx/mab-3

DMRT2 DMRTA1

1.95e-048502IPR026607
DomainGprotein_alpha_I

GNAT3 GNAT2

1.95e-048502IPR001408
DomainZnf_RING

RNF19A NSD2 RNF144A RNF10 TRIM21 RBCK1

2.25e-04326506IPR001841
DomainE3_UB_ligase_RBR

RNF19A RNF144A

3.12e-0410502IPR031127
DomainKRAB

ZNF846 ZNF221 ZNF224 ZNF442 ZNF850 ZIM3

3.71e-04358506PS50805
DomainKRAB

ZNF846 ZNF221 ZNF224 ZNF442 ZNF850 ZIM3

3.71e-04358506PF01352
DomainKRAB

ZNF846 ZNF221 ZNF224 ZNF442 ZNF850 ZIM3

4.36e-04369506SM00349
DomainKRAB

ZNF846 ZNF221 ZNF224 ZNF442 ZNF850 ZIM3

4.42e-04370506IPR001909
DomainLdl_recept_b

EGF LRP1B

6.26e-0414502PF00058
DomainLDLRB

EGF LRP1B

6.26e-0414502PS51120
DomainPLAC

ADAMTS16 ADAMTS18

6.26e-0414502PF08686
DomainIBR

RNF19A RNF144A

6.26e-0414502SM00647
DomainTSP_1

ADAMTS16 ADGRB3 ADAMTS18

6.40e-0463503PF00090
DomainTSP1

ADAMTS16 ADGRB3 ADAMTS18

7.02e-0465503SM00209
DomainTSP1_rpt

ADAMTS16 ADGRB3 ADAMTS18

7.02e-0465503IPR000884
DomainTSP1

ADAMTS16 ADGRB3 ADAMTS18

7.02e-0465503PS50092
DomainLY

EGF LRP1B

7.21e-0415502SM00135
DomainLDLR_classB_rpt

EGF LRP1B

7.21e-0415502IPR000033
DomainG-alpha

GNAT3 GNAT2

8.23e-0416502PF00503
DomainGproteinA_insert

GNAT3 GNAT2

8.23e-0416502IPR011025
DomainG_alpha

GNAT3 GNAT2

8.23e-0416502SM00275
Domain-

GNAT3 GNAT2

8.23e-04165021.10.400.10
DomainGprotein_alpha_su

GNAT3 GNAT2

9.31e-0417502IPR001019
DomainZnf_RING_CS

RNF144A RNF10 TRIM21 RBCK1

9.42e-04163504IPR017907
DomainZF_RING_1

RNF19A RNF144A RNF10 TRIM21 RBCK1

1.06e-03291505PS00518
DomainPLAC

ADAMTS16 ADAMTS18

1.17e-0319502IPR010909
DomainPLAC

ADAMTS16 ADAMTS18

1.17e-0319502PS50900
DomainZF_RING_2

RNF19A RNF144A RNF10 TRIM21 RBCK1

1.18e-03298505PS50089
Domainzf-C2H2_6

ZNF846 ZNF224 ZNF442 ZNF850 ZIM3

1.48e-03314505PF13912
DomainADAM_spacer1

ADAMTS16 ADAMTS18

1.71e-0323502IPR010294
DomainADAM_spacer1

ADAMTS16 ADAMTS18

1.71e-0323502PF05986
DomainPeptidase_M12B_ADAM-TS

ADAMTS16 ADAMTS18

1.87e-0324502IPR013273
Domain-

GLI3 ZNF846 ZNF221 ZNF224 ZNF442 ZNF850 ZIM3

2.09e-036795073.30.160.60
DomainZnf_C2H2/integrase_DNA-bd

GLI3 ZNF846 ZNF221 ZNF224 ZNF442 ZNF850 ZIM3

2.36e-03694507IPR013087
Domainzf-C3HC4

RNF144A RNF10 TRIM21 RBCK1

2.96e-03223504PF00097
DomainEGF_CA

HSPG2 EGF LRP1B

4.26e-03122503SM00179
DomainZINC_FINGER_C2H2_2

GLI3 ZNF846 ZNF221 ZNF224 ZNF442 ZNF850 ZIM3

4.35e-03775507PS50157
DomainZINC_FINGER_C2H2_1

GLI3 ZNF846 ZNF221 ZNF224 ZNF442 ZNF850 ZIM3

4.41e-03777507PS00028
DomainEGF-like_Ca-bd_dom

HSPG2 EGF LRP1B

4.46e-03124503IPR001881
DomainEGF

HSPG2 EGF LRP1B

4.66e-03126503PF00008
DomainPeptidase_M12B_N

ADAMTS16 ADAMTS18

4.89e-0339502IPR002870
Domain-

EGF LRP1B

4.89e-03395022.120.10.30
DomainPep_M12B_propep

ADAMTS16 ADAMTS18

4.89e-0339502PF01562
DomainZnf_C2H2-like

GLI3 ZNF846 ZNF221 ZNF224 ZNF442 ZNF850 ZIM3

5.03e-03796507IPR015880
DomainDISINTEGRIN_1

ADAMTS16 ADAMTS18

5.13e-0340502PS00427
DomainADAM_MEPRO

ADAMTS16 ADAMTS18

5.13e-0340502PS50215
DomainDISINTEGRIN_2

ADAMTS16 ADAMTS18

5.13e-0340502PS50214
DomainLDLR_class-A_CS

HSPG2 LRP1B

5.13e-0340502IPR023415
DomainReprolysin

ADAMTS16 ADAMTS18

5.13e-0340502PF01421
DomainPeptidase_M12B

ADAMTS16 ADAMTS18

5.13e-0340502IPR001590
DomainZnf_C2H2

GLI3 ZNF846 ZNF221 ZNF224 ZNF442 ZNF850 ZIM3

5.34e-03805507IPR007087
DomainCYSTEINE_SWITCH

ADAMTS16 ADAMTS18

5.39e-0341502PS00546
DomainDisintegrin_dom

ADAMTS16 ADAMTS18

5.39e-0341502IPR001762
DomainZnF_C2H2

GLI3 ZNF846 ZNF221 ZNF224 ZNF442 ZNF850 ZIM3

5.45e-03808507SM00355
DomainPept_M10_metallopeptidase

ADAMTS16 ADAMTS18

5.91e-0343502IPR001818
DomainLdl_recept_a

HSPG2 LRP1B

6.46e-0345502PF00057
Domain-

HSPG2 LRP1B

6.74e-03465024.10.400.10
Domain6-blade_b-propeller_TolB-like

EGF LRP1B

6.74e-0346502IPR011042
Domain-

RNF19A NSD2 RNF10 TRIM21 RBCK1

6.84e-034495053.30.40.10
PathwayBIOCARTA_WNT_LRP6_PATHWAY

DKK1 DKK2

8.93e-056352MM1588
PathwayBIOCARTA_WNT_LRP6_PATHWAY

DKK1 DKK2

8.93e-056352M22083
PathwayREACTOME_SIGNALING_BY_LRP5_MUTANTS

DKK1 DKK2

8.93e-056352M27432
PathwayREACTOME_NEGATIVE_REGULATION_OF_TCF_DEPENDENT_SIGNALING_BY_WNT_LIGAND_ANTAGONISTS

DKK1 DKK2

1.66e-048352MM14976
Pubmed

A family of structurally related RING finger proteins interacts specifically with the ubiquitin-conjugating enzyme UbcM4.

RNF19A RNF144A RBCK1

1.65e-07851310431818
Pubmed

A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.

TES GLI3 RNF10 FHL2 CRIP3 PLXNA2 ZMYM3 CRIP2 LHX9

8.19e-0770951922988430
Pubmed

Spatial Multi-omics Reveals the Role of the Wnt Modulator, Dkk2, in Palatogenesis'.

DKK1 GLI3 DKK2

8.41e-071351338910391
Pubmed

The roles of Wnt signaling modulators Dickkopf-1 (Dkk1) and Dickkopf-2 (Dkk2) and cell maturation state in osteogenesis on microstructured titanium surfaces.

DKK1 DKK2

2.11e-06251220004015
Pubmed

Distinct roles of DKK1 and DKK2 in tumor angiogenesis.

DKK1 DKK2

2.11e-06251224091497
Pubmed

Regulation of Wnt/LRP signaling by distinct domains of Dickkopf proteins.

DKK1 DKK2

2.11e-06251212167704
Pubmed

The WNT antagonist Dickkopf2 promotes angiogenesis in rodent and human endothelial cells.

DKK1 DKK2

2.11e-06251221540552
Pubmed

Evaluation of ADAMTS12, ADAMTS16, ADAMTS18 and IL-33 serum levels in pre-eclampsia.

ADAMTS16 ADAMTS18

2.11e-06251226382559
Pubmed

Misexpression of Dickkopf-1 in endothelial cells, but not in chondrocytes or hypertrophic chondrocytes, causes defects in endochondral ossification.

DKK1 DKK2

6.32e-06351222407773
Pubmed

EWS/ETS regulates the expression of the Dickkopf family in Ewing family tumor cells.

DKK1 DKK2

6.32e-06351219247449
Pubmed

Dickkopf genes are co-ordinately expressed in mesodermal lineages.

DKK1 DKK2

6.32e-06351210495270
Pubmed

Expression of Dickkopf genes is strongly reduced in malignant melanoma.

DKK1 DKK2

6.32e-06351216568085
Pubmed

Hypoxia-induced CREB cooperates MMSET to modify chromatin and promote DKK1 expression in multiple myeloma.

DKK1 NSD2

6.32e-06351233420361
Pubmed

Dynamic expression of Wnt signaling-related Dickkopf1, -2, and -3 mRNAs in the developing mouse tooth.

DKK1 DKK2

6.32e-06351215759274
Pubmed

Dkk1, -2, and -3 expression in mouse craniofacial development.

DKK1 DKK2

6.32e-06351216195809
Pubmed

Genetic manipulation of ureteric bud tip progenitors in the mammalian kidney through an Adamts18 enhancer driven tet-on inducible system.

ADAMTS18 GNAT2

6.32e-06351231734175
Pubmed

Wdpcp, a PCP protein required for ciliogenesis, regulates directional cell migration and cell polarity by direct modulation of the actin cytoskeleton.

DKK1 GLI3 DKK2

1.17e-053051324302887
Pubmed

Gli3 is a negative regulator of Tas1r3-expressing taste cells.

GLI3 GNAT3

1.26e-05451229415007
Pubmed

Transcriptional silencing of Dickkopf gene family by CpG island hypermethylation in human gastrointestinal cancer.

DKK1 DKK2

1.26e-05451218461655
Pubmed

Dkk1 and Dkk2 regulate epicardial specification during mouse heart development.

DKK1 DKK2

1.26e-05451220439124
Pubmed

RNF144A sustains EGFR signaling to promote EGF-dependent cell proliferation.

EGF RNF144A

1.26e-05451230171075
Pubmed

Developmental expression of Dkk1-3 and Mmp9 and apoptosis in cranial base of mice.

DKK1 DKK2

1.26e-05451216521043
Pubmed

Glycosaminoglycan-binding properties and aggrecanase activities of truncated ADAMTSs: comparative analyses with ADAMTS-5, -9, -16 and -18.

ADAMTS16 ADAMTS18

1.26e-05451216507336
Pubmed

A case-control study of the association between tooth-development gene polymorphisms and non-syndromic hypodontia in the Chinese Han population.

DKK1 GLI3

1.26e-05451222984994
Pubmed

FHL2 mediates dexamethasone-induced mesenchymal cell differentiation into osteoblasts by activating Wnt/beta-catenin signaling-dependent Runx2 expression.

DKK1 FHL2

1.26e-05451218653765
Pubmed

Second cysteine-rich domain of Dickkopf-2 activates canonical Wnt signaling pathway via LRP-6 independently of dishevelled.

DKK1 DKK2

1.26e-05451211742004
Pubmed

ISLET1-Dependent β-Catenin/Hedgehog Signaling Is Required for Outgrowth of the Lower Jaw.

DKK1 DKK2 LHX9

1.88e-053551328069742
Pubmed

Ectodomains of the LDL receptor-related proteins LRP1b and LRP4 have anchorage independent functions in vivo.

DKK1 LRP1B

2.10e-05551220383322
Pubmed

Genomic organization, expression, and function of bitter taste receptors (T2R) in mouse and rat.

GNAT3 GNAT2

2.10e-05551215886333
Pubmed

Functional and structural diversity of the human Dickkopf gene family.

DKK1 DKK2

2.10e-05551210570958
Pubmed

Wnt antagonists bind through a short peptide to the first β-propeller domain of LRP5/6.

DKK1 DKK2

2.10e-05551221944579
Pubmed

A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.

HSPG2 FAM193B PDIA5 FHL2 PCDH8 FHL5 CRIP2

2.87e-0560851716713569
Pubmed

A family of LIM-only transcriptional coactivators: tissue-specific expression and selective activation of CREB and CREM.

FHL2 FHL5

3.15e-05651211046156
Pubmed

Attenuation of WNT signaling by DKK-1 and -2 regulates BMP2-induced osteoblast differentiation and expression of OPG, RANKL and M-CSF.

DKK1 DKK2

3.15e-05651217971207
Pubmed

Characterisation of the Wnt antagonists and their response to conditionally activated Wnt signalling in the developing mouse forebrain.

DKK1 DKK2

3.15e-05651215527894
Pubmed

Identification of molecular determinants required for interaction of ubiquitin-conjugating enzymes and RING finger proteins.

RNF144A RBCK1

3.15e-05651211722579
Pubmed

Cloning, expression analysis, and structural characterization of seven novel human ADAMTSs, a family of metalloproteinases with disintegrin and thrombospondin-1 domains.

ADAMTS16 ADAMTS18

4.41e-05751211867212
Pubmed

Sexually dimorphic expression of multiple doublesex-related genes in the embryonic mouse gonad.

DMRT2 DMRTA1

4.41e-05751212609607
Pubmed

Functional characterization of WNT7A signaling in PC12 cells: interaction with A FZD5 x LRP6 receptor complex and modulation by Dickkopf proteins.

DKK1 DKK2

4.41e-05751212857724
Pubmed

Vertebrate DM domain proteins bind similar DNA sequences and can heterodimerize on DNA.

DMRT2 DMRTA1

4.41e-05751217605809
Pubmed

The function of Dmrt genes in vertebrate development: it is not just about sex.

DMRT2 DMRTA1

4.41e-05751217720152
Pubmed

TGFβ regulates epithelial-mesenchymal interactions through WNT signaling activity to control muscle development in the soft palate.

DKK1 DKK2

4.41e-05751224496627
Pubmed

The heart LIM protein gene (Hlp), expressed in the developing and adult heart, defines a new tissue-specific LIM-only protein family.

CRIP3 CRIP2

5.87e-05851212128222
Pubmed

Dickkopf 3 Promotes the Differentiation of a Rostrolateral Midbrain Dopaminergic Neuronal Subset In Vivo and from Pluripotent Stem Cells In Vitro in the Mouse.

DKK1 DKK2

5.87e-05851226424886
Pubmed

LDL-receptor-related protein 6 is a receptor for Dickkopf proteins.

DKK1 DKK2

7.54e-05951211357136
Pubmed

Spatial and temporal expression of Wnt and Dickkopf genes during murine lens development.

DKK1 DKK2

7.54e-05951215053977
Pubmed

Single nucleotide polymorphisms associated with aggressive periodontitis and severe chronic periodontitis in Japanese.

HSPG2 EGF

7.54e-05951215081423
Pubmed

Interaction of YY1 with E2Fs, mediated by RYBP, provides a mechanism for specificity of E2F function.

RNF144A FHL2

9.42e-051051212411495
Pubmed

The structure of the G protein heterotrimer Gi alpha 1 beta 1 gamma 2.

GNAT3 GNAT2

9.42e-05105128521505
Pubmed

Direct and indirect control of mitogen-activated protein kinase pathway-associated components, BRAP/IMP E3 ubiquitin ligase and CRAF/RAF1 kinase, by the deubiquitylating enzyme USP15.

RNF144A TRIM21 RBCK1

1.11e-046351323105109
Pubmed

Pdgfrα functions in endothelial-derived cells to regulate neural crest cells and the development of the great arteries.

HSPG2 PLXNA2

1.15e-041151228714851
Pubmed

Dmrt2 promotes transition of endochondral bone formation by linking Sox9 and Runx2.

DMRT2 DMRTA1

1.15e-041151233707608
Pubmed

Embryonic origin and remodeling of the urinary and digestive outlets.

DKK1 DKK2

1.15e-041151223390542
Pubmed

Dmrt genes participate in the development of Cajal-Retzius cells derived from the cortical hem in the telencephalon.

DMRT2 DMRTA1

1.15e-041151232012381
Pubmed

The role of sonic hedgehog-Gli2 pathway in the masculinization of external genitalia.

GLI3 DKK2

1.15e-041151221586556
Pubmed

MTSS1 suppresses mammary tumor-initiating cells by enhancing RBCK1-mediated p65 ubiquitination.

TRIM21 RBCK1

1.38e-041251235122005
Pubmed

Structural determinants for activation of the alpha-subunit of a heterotrimeric G protein.

GNAT3 GNAT2

1.63e-04135128208289
Pubmed

Mechanism of the receptor-catalyzed activation of heterotrimeric G proteins.

GNAT3 GNAT2

1.63e-041351216892066
Pubmed

The E3 ligase subunit FBXO45 binds the interferon-λ receptor and promotes its degradation during influenza virus infection.

RNF10 TRIM21

1.63e-041351236379255
Pubmed

SMAD4-mediated WNT signaling controls the fate of cranial neural crest cells during tooth morphogenesis.

DKK1 DKK2

1.63e-041351221490069
Pubmed

Small-molecule Wnt agonists correct cleft palates in Pax9 mutant mice in utero.

DKK1 DKK2

1.63e-041351228893947
Pubmed

O-fucosylation of thrombospondin type 1 repeats restricts epithelial to mesenchymal transition (EMT) and maintains epiblast pluripotency during mouse gastrulation.

ADAMTS16 ADGRB3 ADAMTS18

1.86e-047551320637190
Pubmed

Morphogenesis of the kidney and lung requires branch-tip directed activity of the Adamts18 metalloprotease.

ADAMTS16 ADAMTS18

1.90e-041451231242448
Pubmed

The SRF target gene Fhl2 antagonizes RhoA/MAL-dependent activation of SRF.

FHL2 FHL5

1.90e-041451215610731
Pubmed

Evolutionary plasticity of segmentation clock networks.

DKK1 LASP1

1.90e-041451221652651
Pubmed

Sonic hedgehog-dependent synthesis of laminin alpha1 controls basement membrane assembly in the myotome.

HSPG2 GLI3

1.90e-041451219783738
Pubmed

Dickkopf-1 (DKK1) reveals that fibronectin is a major target of Wnt signaling in branching morphogenesis of the mouse embryonic lung.

DKK1 DKK2

2.19e-041551215617677
Pubmed

The species-specific differences in the cAMP regulation of the tissue-type plasminogen activator gene between rat, mouse and human is caused by a one-nucleotide substitution in the cAMP-responsive element of the promoters.

ADAMTS16 ADAMTS18

2.19e-04155127543410
Pubmed

Foxg1 coordinates the switch from nonradially to radially migrating glutamatergic subtypes in the neocortex through spatiotemporal repression.

DMRTA1 LHX9

2.19e-041551223523356
Pubmed

Mutations in DMRT3 affect locomotion in horses and spinal circuit function in mice.

DMRT2 DMRTA1

2.19e-041551222932389
Pubmed

Cloning and characterization of the human phosphoinositide-specific phospholipase C-beta 1 (PLC beta 1).

GNAT3 GNAT2

2.19e-041551211118617
Pubmed

Paleocortex is specified in mice in which dorsal telencephalic patterning is severely disrupted.

GLI3 LHX9

2.50e-041651214566948
Pubmed

ADAMTS18 Deficiency Affects Neuronal Morphogenesis and Reduces the Levels of Depression-like Behaviors in Mice.

ADAMTS16 ADAMTS18

2.50e-041651230579834
Pubmed

GLI3 repressor but not GLI3 activator is essential for mouse eye patterning and morphogenesis.

DKK1 GLI3

2.50e-041651230953627
Pubmed

Secreted Wnt antagonist Dickkopf-1 controls kidney papilla development coordinated by Wnt-7b signalling.

DKK1 DKK2

2.50e-041651221354128
Pubmed

Regional Control of Hairless versus Hair-Bearing Skin by Dkk2.

DKK1 DKK2

2.50e-041651230509557
Pubmed

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

HAUS6 TES GNAT3 LASP1 GNAT2 FHL2 ZMYM3 LGALS3BP

2.59e-04115551820360068
Pubmed

Maturation of human dendritic cells is accompanied by functional remodelling of the ubiquitin-proteasome system.

RNF19A TRIM21 RBCK1

2.70e-048551319028597
Pubmed

Wnt signaling in the murine diastema.

DKK1 DKK2

2.83e-041751221531785
Pubmed

The Dkk1 dose is critical for eye development.

DKK1 GLI3

3.55e-041951221539829
Pubmed

A Proteomic Variant Approach (ProVarA) for Personalized Medicine of Inherited and Somatic Disease.

TRIM21 LGALS3BP

3.55e-041951229924966
Pubmed

Activity-based E3 ligase profiling uncovers an E3 ligase with esterification activity.

RNF19A RNF10 RBCK1

3.74e-049551329643511
Pubmed

Fuz regulates craniofacial development through tissue specific responses to signaling factors.

GLI3 PCDH8

3.94e-042051221935430
Pubmed

Pax9 and Jagged1 act downstream of Gli3 in vertebrate limb development.

GLI3 LHX9

3.94e-042051216169709
Pubmed

The negative regulator of Gli, Suppressor of fused (Sufu), interacts with SAP18, Galectin3 and other nuclear proteins.

RNF19A GLI3

3.94e-042051214611647
Pubmed

Differential expansion of zinc-finger transcription factor loci in homologous human and mouse gene clusters.

ZNF221 ZNF224

3.94e-042051212743021
Pubmed

Expanding the Interactome of TES by Exploiting TES Modules with Different Subcellular Localizations.

TES DDX60 LASP1 FHL2

3.96e-0423551428378594
Pubmed

The transcription factor Foxg1 regulates the competence of telencephalic cells to adopt subpallial fates in mice.

GLI3 LHX9

4.35e-042151220081193
Pubmed

Patterns of Wnt pathway activity in the mouse incisor indicate absence of Wnt/beta-catenin signaling in the epithelial stem cells.

DKK1 DKK2

4.35e-042151219806668
Pubmed

Loss of Sip1 leads to migration defects and retention of ectodermal markers during lens development.

DKK1 PLXNA2

4.35e-042151224161570
Pubmed

Proteomics characterization of extracellular space components in the human aorta.

HSPG2 CRIP2 LGALS3BP

4.47e-0410151320551380
Pubmed

LASP-1: a nuclear hub for the UHRF1-DNMT1-G9a-Snail1 complex.

PDIA5 LASP1

4.78e-042251225982273
Pubmed

Loss of Tgif function causes holoprosencephaly by disrupting the SHH signaling pathway.

DKK1 GLI3

4.78e-042251222383895
Pubmed

Systematic analysis of dimeric E3-RING interactions reveals increased combinatorial complexity in human ubiquitination networks.

RNF10 TRIM21 RBCK1

5.01e-0410551322493164
Pubmed

Zic2-dependent axon midline avoidance controls the formation of major ipsilateral tracts in the CNS.

PLXNA2 LHX9

5.23e-042351224360543
Pubmed

A novel role for cilia-dependent sonic hedgehog signaling during submandibular gland development.

EGF GLI3

5.23e-042351229532549
Pubmed

Secreted metalloproteases ADAMTS9 and ADAMTS20 have a non-canonical role in ciliary vesicle growth during ciliogenesis.

HSPG2 GLI3

5.23e-042351230814516
Pubmed

Screening large numbers of expression patterns of transcription factors in late stages of the mouse thymus.

LASP1 FHL2 CRIP3 LHX9

6.04e-0426351420932939
Pubmed

T-box3 is a ciliary protein and regulates stability of the Gli3 transcription factor to control digit number.

DKK1 GLI3

6.19e-042551227046536
Pubmed

Loss of Ezh2 promotes a midbrain-to-forebrain identity switch by direct gene derepression and Wnt-dependent regulation.

DMRTA1 DKK2

6.19e-042551226621269
InteractionZNF408 interactions

HSPG2 ZNF330 FHL2 LRP1B FHL5

2.66e-05145495int:ZNF408
InteractionPDLIM7 interactions

TES DMRT2 RNF10 ZCCHC7 FHL5 RBCK1

4.16e-05264496int:PDLIM7
InteractionZNF23 interactions

ZNF330 FHL2 FHL5

4.72e-0529493int:ZNF23
InteractionADAMTS19 interactions

ADAMTS16 ADAMTS18

5.76e-055492int:ADAMTS19
CytobandEnsembl 112 genes in cytogenetic band chr9p13

FAM240B ZCCHC7 MSMP

9.75e-04174513chr9p13
GeneFamilyLIM domain containing

TES LASP1 FHL2 CRIP3 FHL5 CRIP2

2.37e-09593861218
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF330 GLI3 ZNF846 ZNF221 ZNF224 ZNF442 ZNF850 ZIM3

1.01e-0471838828
GeneFamilyRing finger proteins

RNF19A RNF144A RNF10 TRIM21 RBCK1

2.61e-0427538558
GeneFamilyADAM metallopeptidases with thrombospondin type 1 motif

ADAMTS16 ADAMTS18

7.19e-041938250
CoexpressionGSE10325_CD4_TCELL_VS_LUPUS_CD4_TCELL_DN

SOBP DDX60 TRIM21 FHL2 LGALS3BP RBCK1

2.41e-06199516M3093
CoexpressionGSE3920_UNTREATED_VS_IFNB_TREATED_ENDOTHELIAL_CELL_DN

NSD2 DDX60 SLC44A2 TRIM21 ZMYM3

2.30e-05175515M6694
CoexpressionGSE21927_SPLEEN_C57BL6_VS_4T1_TUMOR_BALBC_MONOCYTES_DN

SOBP DDX60 TRIM21 LGALS3BP RBCK1

4.35e-05200515M7595
CoexpressionGSE13484_UNSTIM_VS_YF17D_VACCINE_STIM_PBMC_DN

SOBP DDX60 TRIM21 LGALS3BP RBCK1

4.35e-05200515M3279
CoexpressionAtlasdev gonad_e11.5_F_SupCellPrec_Sry_top-relative-expression-ranked_1000

RNF19A SOBP DDX60 ADAMTS16 DMRTA1 ZCCHC7 PLXNA2 ZMYM3 MSMP LHX9

7.20e-067914710gudmap_dev gonad_e11.5_F_SupCellPrec_Sry_1000
CoexpressionAtlasdev gonad_e13.5_F_SupCellPrec_Sry_top-relative-expression-ranked_1000

AKR1E2 SOBP ZNF846 ADAMTS16 DMRTA1 TRIM21 ZCCHC7 CRIP3 ZMYM3 LHX9

8.31e-068044710gudmap_dev gonad_e13.5_F_SupCellPrec_Sry_1000
CoexpressionAtlaskidney_adult_RenMedVasc_Tie2_top-relative-expression-ranked_1000

HSPG2 DDX60 RNF144A SLC44A2 PDIA5 TRIM21 PLXNA2 DKK2 CRIP2 LGALS3BP

1.35e-058504710gudmap_kidney_adult_RenMedVasc_Tie2_1000
CoexpressionAtlasAravindRamakr_EmbryoidBody-LF_top-relative-expression-ranked_500_k-means-cluster#2

GDAP1L1 ADAMTS16 ADAMTS18 PCDH8 DKK2 LHX9

2.01e-05255476Arv_EB-LF_500_K2
CoexpressionAtlasdev gonad_e12.5_F_SupCellPrec_Sry_top-relative-expression-ranked_500

AKR1E2 SOBP ADAMTS16 DMRTA1 TRIM21 ZMYM3 LHX9

3.27e-05414477gudmap_dev gonad_e12.5_F_SupCellPrec_Sry_500
CoexpressionAtlaskidney_adult_Mesangium_Meis_top-relative-expression-ranked_500

DDX60 RNF144A TRIM21 FHL2 DKK2 CRIP2 LGALS3BP

4.10e-05429477gudmap_kidney_adult_Mesangium_Meis_500
CoexpressionAtlasdev gonad_e12.5_F_SupCellPrec_Sry_k-means-cluster#2_top-relative-expression-ranked_500

SOBP ADAMTS16 ZMYM3

9.48e-0540473gudmap_dev gonad_e12.5_F_SupCellPrec_Sry_k2_500
CoexpressionAtlasProgenitor-Cell-Biology-Consortium_EmbryoidBody_from_inducedPluripotentialStemCells_derived from_from_fibroblast_top-relative-expression-ranked_500

GDAP1L1 ADAMTS16 ADAMTS18 LRP1B PCDH8 DKK2 LHX9

1.03e-04497477PCBC_EB_fibroblast_500
CoexpressionAtlaskidney_adult_CortVasc_Tie2_k-means-cluster#4_top-relative-expression-ranked_1000

DDX60 TRIM21 DKK2 LGALS3BP

2.45e-04138474gudmap_kidney_adult_CortVasc_Tie2_k4_1000
CoexpressionAtlaskidney_adult_Mesangium_Meis_k-means-cluster#4_top-relative-expression-ranked_1000

DDX60 SLC44A2 TRIM21 CRIP2 LGALS3BP

2.58e-04258475gudmap_kidney_adult_Mesangium_Meis_k4_1000
CoexpressionAtlaskidney_adult_RenMedVasc_Tie2_top-relative-expression-ranked_500

DDX60 SLC44A2 PDIA5 DKK2 CRIP2 LGALS3BP

3.01e-04417476gudmap_kidney_adult_RenMedVasc_Tie2_500
CoexpressionAtlasdev gonad_e12.5_M_InterstitTestis_Sma_top-relative-expression-ranked_1000

DKK1 RNF19A GLI3 RNF144A ADAMTS16 LASP1 ZMYM3 LHX9

3.16e-04793478gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_1000
CoexpressionAtlasdev gonad_e12.5_F_SupCellPrec_Sry_top-relative-expression-ranked_1000

AKR1E2 SOBP ADAMTS16 DMRTA1 TRIM21 ZCCHC7 ZMYM3 LHX9

3.43e-04803478gudmap_dev gonad_e12.5_F_SupCellPrec_Sry_1000
CoexpressionAtlasDevelopingKidney_e13.5_podocyte cells_emap-27773_top-relative-expression-ranked_500

DMRT2 DKK1 ADGRB3 ADAMTS18 PCDH8 DKK2

3.59e-04431476gudmap_developingKidney_e13.5_podocyte cells_500
ToppCellMild/Remission-B_activate-7|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)

SOBP DDX60 ZCCHC7 LGALS3BP RBCK1

2.83e-0619451501c97543972159a9468272da06e7e611e2c21fae
ToppCellB_cells-ISG-high_B_cells|B_cells / Immune cells in Kidney/Urine in Lupus Nephritis

RNF19A SOBP DDX60 TRIM21 RBCK1

2.90e-06195515b64d9e1a8834401b4dc501566546647754ae21fc
ToppCellCOVID-19-kidney-AQP1+PLVAP+EC|kidney / Disease (COVID-19 only), tissue and cell type

HSPG2 RNF144A ADGRB3 PLXNA2 CRIP2

3.13e-061985158689090bce9ab6e8f122426a404037e572c6713b
ToppCellVE-CD4-antiviral_CD4|VE / Condition, Cell_class and T cell subcluster

SOBP DDX60 TRIM21 LGALS3BP RBCK1

3.21e-06199515056a0538ca5e825ae6195b4c76c208708a014533
ToppCellmetastatic_Lymph_Node-Myeloid_cells-Alveolar_Mac|Myeloid_cells / Location, Cell class and cell subclass

EGF SOBP ADGRB3 DKK2

2.06e-05141514399380de5ea09e22fd128e3e55fffeffc4874c15
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RNF144A PDIA5 DKK2 CRIP2

3.90e-051665147a45785a40b7425f97be67bab1c5ceb69b2bd85a
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell_prolif|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

HSPG2 GLI3 ADGRB3 PDIA5

3.90e-051665149d4b44eb56ad38c26aed73444edf389abca6bdf6
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RNF144A PDIA5 DKK2 CRIP2

3.90e-05166514bbd382812f8a84a5d99888de2d7cca3a8b5e4695
ToppCellT_cells-ISG-high_CD4+_T_cells|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis

SOBP DDX60 TRIM21 LGALS3BP

5.23e-05179514af35ef8a7768cee0c2af0590e5bec35cee6a4714
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ADAMTS16 LRP1B DKK2 CRIP2

5.23e-05179514445eeb0356d9fd894aa33dd9f45d893b21424149
ToppCell3'-GW_trimst-2-LargeIntestine-Mesenchymal-myocytic-SMC_(PLPP2+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TES DKK1 FHL2 DKK2

5.23e-05179514e860dca9b28ac5af61804bfd729cd39257cdb352
ToppCell3'_v3-blood-Hematopoietic_Erythro-Mega-Mega-Mast|blood / Manually curated celltypes from each tissue

EGF PDIA5 FHL2 ZNF442

5.58e-051825141923b5669901f828e890416c22d1f1d21a4a2c6a
ToppCell3'-GW_trimst-2-SmallIntestine-Mesenchymal-stromal_related-ICC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SOBP FHL2 LRP1B DKK2

5.70e-05183514262387ee8d43b96e5f1a77c75124459a506a6172
ToppCell3'-GW_trimst-2-SmallIntestine-Mesenchymal-stromal_related|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SOBP FHL2 LRP1B DKK2

5.70e-05183514c85a707acbcb582912e8ac080a36d05f91cfd7a2
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

HSPG2 RNF144A ADGRB3 PDIA5

5.82e-05184514688428103e8b19f45f2f65d70a0f30c904c8411c
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ADAMTS16 PLXNA2 DKK2 CRIP2

5.82e-05184514ca35a3d2b536c8b2bf5c4d635605e5a3ae94a428
ToppCell3'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-venous_capillary|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HSPG2 DMRTA1 ZNF850 CRIP2

5.95e-05185514a987dbf6adf533c5f8a0a8a465a6c8e67e0ffcc8
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_artery-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

HSPG2 PLXNA2 DKK2 CRIP2

5.95e-05185514a7ae76058b2082020cadec49d63b9f4e24d21734
ToppCellAT1_cells-SSc-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

HSPG2 TES DKK1 CRIP2

6.20e-05187514f1dda349335e08dbfc8395d373924037f5ad2fd6
ToppCelldroplet-Kidney-nan-18m-Endothelial-fenestrated_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 PDIA5 DKK2 CRIP2

6.46e-0518951491261fe86f0d54b9697f85bb4d3ebdc8975b1bfa
ToppCellfacs-Kidney-nan-24m-Endothelial-fenestrated_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 RNF144A PDIA5 CRIP2

6.46e-051895149d02a824bba59ea0660439f0510d843568e9d8c3
ToppCell(2)_NK/T-(210)_NKT_cell|(2)_NK/T / immune cells in Peripheral Blood (logTPM normalization)

TES RNF19A LASP1 RBCK1

6.46e-05189514fa72e87e1e8cd7cbddae7b47e19cf90d181820a7
ToppCellfacs-Kidney-nan-24m-Endothelial|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 RNF144A PDIA5 CRIP2

6.46e-051895145f8d4b61296c71b32362432a9ce4c1c3aaeb278d
ToppCellfacs-Kidney-nan-24m-Endothelial-Pecam____fenestrated_capillary_endothelial|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 RNF144A PDIA5 CRIP2

6.46e-0518951418f82764b32496e54d1a604a531b261651c5e110
ToppCell3'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_venous_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HSPG2 ADAMTS18 GNAT2 CRIP2

6.46e-05189514fccadf8efbef17b7f12291b069c71060a71b04e2
ToppCell(2)_NK/T-(21)_NKT_cell|(2)_NK/T / immune cells in Peripheral Blood (logTPM normalization)

TES RNF19A LASP1 RBCK1

6.46e-05189514b37ad24898a14a4a3b2d6cea2637de2471f76e20
ToppCelldroplet-Kidney-nan-18m-Endothelial-Pecam____fenestrated_capillary_endothelial|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 PDIA5 DKK2 CRIP2

6.46e-0518951488c0dda28f072368c0df30fc82ee3af9c7670f6c
ToppCellPND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RNF144A PDIA5 DKK2 CRIP2

6.46e-051895149da012fdfa9a8d488cab710a463a1d70e89f990c
ToppCell5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TES LASP1 FHL5 CRIP2

6.59e-05190514a7f6c38bbf451f166febb21e6719d4afced4035e
ToppCelldroplet-Kidney-nan-3m-Endothelial|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 PDIA5 DKK2 CRIP2

6.73e-05191514dc58d45fafd224d2761aefbe0ce79f66b50c1c03
ToppCellnucseq-Endothelial-Endothelial_Vascular-Endothelial_large_blood_vessel-AEC|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

HSPG2 PLXNA2 DKK2 CRIP2

6.73e-0519151450601ef0a5a8f2c2120922989e08e85bf2d9b4ab
ToppCellPND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RNF144A PDIA5 DKK2 CRIP2

6.73e-0519151427f23c2254b610abac1a88d0fecff305addde9da
ToppCellPND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RNF144A PDIA5 DKK2 CRIP2

6.73e-051915143307dbccadb09c62b0e1c0235ec89bb294d748c3
ToppCellMild/Remission-B_activate-7|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

DDX60 ZCCHC7 LGALS3BP RBCK1

6.73e-05191514382686d62f7b8576c44bb9726a4e10dc26fd348e
ToppCell10x5'v1-week_12-13-Mesenchymal_fibro-stroma|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

SOBP GLI3 CRIP2 LHX9

6.87e-051925144ed5040594ba2d0639f0990697504ecef872ca70
ToppCellfacs-Kidney-nan-18m-Endothelial-fenestrated_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 PLXNA2 DKK2 CRIP2

6.87e-05192514777e386a17bba9ec450bb9d64d8a9ab98d9a63ff
ToppCellfacs-Kidney-nan-18m-Endothelial|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 PLXNA2 DKK2 CRIP2

6.87e-0519251460a2409546525a40a5658e0f9d6a50c37f28bb96
ToppCellCOVID-19-kidney-AQP1+PLVAP+EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

HSPG2 RNF144A ADGRB3 CRIP2

6.87e-0519251427ff3621e177e7932dd44dd6baa81551ea75a874
ToppCell10x5'v1-week_12-13-Mesenchymal_fibro|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

SOBP GLI3 CRIP2 LHX9

6.87e-05192514d4f5d6653564c2c5d0f5f7c932d89cb1b1412844
ToppCellfacs-Kidney-nan-18m-Endothelial-Pecam____fenestrated_capillary_endothelial|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 PLXNA2 DKK2 CRIP2

6.87e-051925140f9db6091b373334b9beabe0e5782bf2bc54690b
ToppCellfacs-Aorta-Heart-3m|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NSD2 SLC44A2 PDIA5 DKK2

6.87e-051925141ccc47792edf9ee23501c8e2165d11271636b66a
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-stromal_related|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SOBP FHL2 LRP1B CRIP2

7.01e-05193514f27e2be497745098b5269aa799dd3d5f62d78ba7
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HSPG2 ADGRB3 ADAMTS18 PDIA5

7.01e-051935141f978e102a029a6beb10913052cd0a20c7253e8e
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-stromal_related-ICC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SOBP FHL2 LRP1B CRIP2

7.01e-051935144ccf984baebbb13ae916727137ce593fda7514a2
ToppCell390C-Endothelial_cells-Endothelial-B_(Artery)|390C / Donor, Lineage, Cell class and subclass (all cells)

HSPG2 PLXNA2 DKK2 CRIP2

7.15e-05194514f8a59bd4609d147d8a706bf606e9e8173c9992a3
ToppCell390C-Endothelial_cells-Endothelial-B_(Artery)-|390C / Donor, Lineage, Cell class and subclass (all cells)

HSPG2 PLXNA2 DKK2 CRIP2

7.15e-0519451404b1acc2e879feafb43f75435281c5acd8d23be2
ToppCell(6)_Endothelial-B_(Artery)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

HSPG2 PLXNA2 DKK2 CRIP2

7.15e-051945140cf4e67d4024652794b5bfdd4a71a7d98900b4c8
ToppCelldroplet-Kidney-nan-21m-Endothelial-fenestrated_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 PDIA5 DKK2 CRIP2

7.29e-0519551437d22a6448db1f83d098018fbb75a6dd8d9be302
ToppCelldroplet-Kidney-nan-21m-Endothelial-Pecam____fenestrated_capillary_endothelial|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 PDIA5 DKK2 CRIP2

7.29e-0519551437592b7ad912b381b1edc77f4032983f26e0aa5b
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-2M-Neuronal-midbrain/hindbrain_cells|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.

GDAP1L1 TES SOBP LHX9

7.44e-051965140767581b69bc7e6334d580ca02ed1e831b7b55da
ToppCell5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SOBP FHL2 PCDH8 CRIP2

7.44e-05196514308fa54385ca34e9e590967d4553b84aad96c92f
ToppCellmild-Myeloid-Neutrophils_2|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

DDX60 RNF10 TRIM21 RBCK1

7.44e-05196514ded44b38ea489946e9eedfe752b5a9fde9149c16
ToppCellMild-CD4+_T_activated|World / Disease group and Cell class

DDX60 TRIM21 LGALS3BP RBCK1

7.44e-05196514417b4fc2e4388f34c410576131b02936f93e46b6
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HSPG2 ADGRB3 PDIA5 PLXNA2

7.44e-05196514e224338490691d92c1f70b57112fabdcc92b06a9
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HSPG2 ADGRB3 PDIA5 PLXNA2

7.58e-05197514c10dd1aaec01fb662eac83dfde90e3e426665d65
ToppCellCD8+_Memory_T_cell-CV-1|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

DDX60 TRIM21 LGALS3BP RBCK1

7.58e-05197514e59b47bccc781b2117196fe322efa87559c237c6
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HSPG2 ADGRB3 PDIA5 PLXNA2

7.58e-051975142844dbcd0a673ed81c99920aa45858651a00736d
ToppCellFibroblasts-DKK3+_Fibroblasts|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

HSPG2 SOBP GLI3 CRIP2

7.73e-051985144f4632f26a2043c5e4ab89031b4229b5dca1bd48
ToppCellproximal-Epithelial-Neuroendocrine|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

LYZL2 GDAP1L1 ADAMTS18 PCDH8

7.73e-051985145dea6078488d584513c0bdbf5bba54877310b54a
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HSPG2 RNF144A ADGRB3 PDIA5

7.73e-051985141378c6d4ceb84b42fdd6556be3296df7a8059e6e
ToppCell5'-Adult-SmallIntestine-Endothelial-blood_vessel_EC-Mature_arterial_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HSPG2 PLXNA2 DKK2 CRIP2

7.73e-0519851458508a8df2714d769f137794c29441a7bd38b350
ToppCellproximal-Epithelial-Neuroendocrine-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

LYZL2 GDAP1L1 ADAMTS18 PCDH8

7.73e-0519851400ccf3020667cf2130bc354b441b65c0b1b0e862
ToppCellEpithelial_cells-AT1-AT2_cells|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id

HSPG2 TES DKK1 CRIP2

7.73e-05198514fbc46b20bcd44f2083170aacbc6f5dd00fba685c
ToppCellproximal-3-Epithelial-Neuroendocrine|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

LYZL2 GDAP1L1 ADAMTS18 PCDH8

7.73e-05198514a6bc043faf68468d46bac441cf7447c236c7bae4
ToppCell(7)_Epithelial_cells-(7)_Epithelial-I_(AT1)|(7)_Epithelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)

HSPG2 TES DDX60 CRIP2

7.89e-051995145a002d49a8b84c158f7b4d7a3e78e6a937757bb7
ToppCellBronchial-10x5prime-Endothelial-Endothelia_vascular-VE_systemic_arterial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

HSPG2 GNAT2 DKK2 CRIP2

7.89e-051995146a2943a23fdd2ec814662db7c21a0d6804a6cbbc
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_arterial|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

HSPG2 PLXNA2 MSMP CRIP2

7.89e-051995140602e2b2aa56d106da63bd342a38bef437b4d496
ToppCell390C-Endothelial_cells-Endothelial-B_(Artery)-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

HSPG2 TES PLXNA2 DKK2

8.04e-05200514c32ad15dede3f879007c0b856f2fed1f5b058103
ToppCellParenchymal-10x3prime_v2-Endothelial-Endothelia_vascular-VE_systemic_arterial|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

HSPG2 DDX60 DKK2 CRIP2

8.04e-05200514a8b59e6fe04271fef61db911a286b5c48438bb84
ToppCell390C-Endothelial_cells-Endothelial-B_(Artery)|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

HSPG2 TES PLXNA2 DKK2

8.04e-052005148a2c6c53a39fab86750526083f7254b7413b29af
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

HSPG2 PLXNA2 MSMP CRIP2

8.04e-05200514061ba851f941c616ddb462512e826c412881c3ce
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Mme_Fam114a1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

DMRT2 PCDH8 LHX9

2.58e-041085134536cbe1748aee37f0a13648c5679fd592af6322
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Calb2_Necab1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

DMRT2 ADAMTS18 PCDH8

4.05e-0412651328fbe63f7bc628b32d8e86bf9e80657e776dd1cc
ToppCell(00)_Basal-(3)_72hpi|(00)_Basal / shred by cell type and Timepoint

TES RNF10 CRIP2

5.06e-04136513d68452500df2f75b803cfd4addb2d15cbcc706f2
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Crh_4930553C11Rik_|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

DMRT2 ADAMTS18 PCDH8

5.62e-04141513ad9a25569c142fb68ded34aeba0cd9be8124ce56
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CACNG6 ADAMTS16 DMRTA1

6.34e-041475132885978bcfc5623967c0c1204dadf5c78c74a082
ToppCellIIH-CD4-antiviral_CD4|IIH / Condition, Cell_class and T cell subcluster

DDX60 TRIM21 CRIP2

6.47e-04148513ec626a44cea83f2a0e5c27fc8182f96446d297ac
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

EGF DMRTA1 DKK2

6.60e-04149513c5eedb54ef2e0f131aa6730612c921bc19479632
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_granulocytic|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

EGF DMRTA1 DKK2

6.60e-04149513a22417286de8606f0cc94f86b70bce17aeefb9c2
ToppCellSerous|World / shred by cell class for turbinate

EGF ADAMTS18 MSMP

6.73e-041505136a326662d58b0f17d6efa8cc28571f4cbbf57c2d
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

AKR1E2 HSPG2 CRIP2

6.73e-04150513322aa0c3fc159a4b2897daac881dfc744b24ffc4
ToppCellBasal_cells-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

HSPG2 ADGRB3 FHL2

6.99e-0415251372499e4d2b374ef5f1621c89d94727ecf4bd4d5d
ToppCellmild_COVID-19_(asymptomatic)-CD8+_T_naive|World / disease group, cell group and cell class (v2)

DDX60 DMRTA1 ZNF850

6.99e-04152513f944743f40ff6ed3a7a096dd53e12d3526c67c4d
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-4_VIP_CHRNA2|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DKK1 GNAT3 TRIM21

7.40e-04155513523a821963d2aecb67da7133a9a4b3bc33309b58
ToppCellE16.5-samps-Mesenchymal-Myofibroblast-Migrating_MyoFibroblast|E16.5-samps / Age Group, Lineage, Cell class and subclass

FHL2 PLXNA2 MSMP

7.40e-041555131882fa5fd25f77d6e3ac47b613f6fb3c67d8e50c
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HSPG2 ADGRB3 PDIA5

7.54e-04156513f894fac4e44a23718b20ad80c9677bf4f2118002
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

EGF NSD2 ADAMTS16

7.54e-041565134d2679e7639758c49fc25a2deb9109b08f0a3e57
ToppCellfacs-Lung-24m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell-natural_killer|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TES DMRTA1 FHL2

7.68e-0415751334eb1cbdb023d3e23b2e1695c9c327c21ef1c870
ToppCellfacs-Lung-EPCAM-24m-Lymphocytic-NK_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TES DMRTA1 FHL2

7.68e-04157513af110085dad5d26b0b7068a78f104ba784fa8564
ToppCellfacs-Lung-EPCAM-24m-Lymphocytic-Natural_Killer|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TES DMRTA1 FHL2

7.68e-04157513071f10d749b590b75a07ab3c7b00956dc7cda4da
ToppCellfacs-Lung-24m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TES DMRTA1 FHL2

7.68e-04157513fc0c222124f59c94d60335f849554eaa4062f8c7
ToppCellfacs-Lung-24m-Hematologic-Lymphocytic_NK_ILC|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TES DMRTA1 FHL2

7.68e-0415751340b08ace1d9ea7951886f5fed76ac57e9175436b
ToppCellTransplant_Alveoli_and_parenchyma-Epithelial-Type_1_alveolar|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

HSPG2 DKK1 CRIP2

8.11e-0416051358ed3a074932ccc951e07868dfdc61b99ae1cc2b
ToppCellsevere_influenza-cDC|World / disease group, cell group and cell class (v2)

DMRTA1 CRIP3 LRP1B

8.26e-04161513802f8cafb5f499e3b2ec0193d6eb1ac9320b9287
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

RNF144A ADGRB3 FHL5

8.26e-041615131b805f77790aeb8a71b08bfac2fe2eed7343258f
ToppCellsevere_influenza-cDC|severe_influenza / disease group, cell group and cell class (v2)

DMRTA1 CRIP3 LRP1B

8.26e-041615137716315b8bda904b346cea47edc2c0b507a345c2
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-Degenerative_Endothelial_Cell-Degenerative_Peritubular_Capilary_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

HSPG2 ADGRB3 PDIA5

8.56e-0416351373c03e29a6d7a6863c5e9aa5e8b963ef691f1ddb
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal--glomerular_mesenchymal_cell-Renin-positive_Juxtaglomerular_Granular_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RNF144A ADGRB3 FHL2

8.71e-0416451343630a448f4369fa9e4e3eccdf3b9f29cec16c39
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RNF144A ADGRB3 FHL2

8.71e-04164513108fbecb56d69a675d6ce6e826a873ae528f2fd7
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal--glomerular_mesenchymal_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RNF144A ADGRB3 FHL2

8.71e-0416451346208f18325976c89f572f6627aea0582142b92d
Diseaseanodontia (is_implicated_in)

DKK1 GLI3

2.80e-055502DOID:13714 (is_implicated_in)
DiseaseMcCune Albright syndrome (implicated_via_orthology)

GNAT3 GNAT2

7.83e-058502DOID:1858 (implicated_via_orthology)
Diseasegallbladder cancer (is_implicated_in)

EGF LRP1B

2.17e-0413502DOID:3121 (is_implicated_in)
Diseasepursuit maintenance gain measurement

ZNF846 FHL2 PLXNA2

1.20e-03123503EFO_0008433
Diseaselung non-small cell carcinoma (is_implicated_in)

EGF NSD2 LRP1B

1.71e-03139503DOID:3908 (is_implicated_in)
Diseasespleen volume

EGF DMRTA1

2.43e-0343502EFO_0600047
Diseaselung adenocarcinoma (is_implicated_in)

EGF LRP1B

3.15e-0349502DOID:3910 (is_implicated_in)
Diseasecongenital heart disease

SLC44A2 LRP1B

4.53e-0359502EFO_0005207
DiseaseColorectal Carcinoma

GDAP1L1 GLI3 ADAMTS18 DMRTA1 ZNF442

6.58e-03702505C0009402

Protein segments in the cluster

PeptideGeneStartEntry
FGCHVLCTWLESCLK

ADGRB3

166

O60242
EGFCCARHFWTKICK

DKK2

191

Q9UBU2
CEAAHLGLWKACTKR

CACNG6

76

Q9BXT2
LDFKKDICKALWCHR

ADAMTS16

531

Q8TE57
DICKALWCHRIGRKC

ADAMTS16

536

Q8TE57
FVKDICKSLWCHRVG

ADAMTS18

536

Q8TE60
HCALKLWRCDGDFDC

HSPG2

336

P98160
KCELWLCGCAFTLAD

GDAP1L1

256

Q96MZ0
IHGEKKEFVCRWLDC

GLI3

506

P10071
SERKKWIHCFEGVTC

GNAT3

206

A8MTJ3
KCISKHWICDGEDDC

LRP1B

2731

Q9NZR2
KHCEGRDLSDWKKDC

LYZL2

131

Q7Z4W2
ADCKSLGWLKSNCRH

LGALS3BP

101

Q08380
KKDGCDWIRCTVCHT

RBCK1

456

Q9BYM8
LDKFWHKACFHCETC

LASP1

21

Q14847
ACLKAWKEHCRSEEG

DDX60

646

Q8IY21
CGLCLKADRKFECGW

PLXNA2

811

O75051
AVDKQWHLRCLKCCE

LHX9

86

Q9NQ69
WHLRCLKCCECKLAL

LHX9

91

Q9NQ69
CTAECKILGHSDRCW

PCDH8

951

O95206
SWFCNDCRAGKKLHF

NSD2

866

O96028
CKHAFCWYCLESLDD

RNF144A

206

P50876
CYKDRHWHEGCFKCT

FHL5

56

Q5TD97
LWHKECFLCSGCRKD

FHL5

181

Q5TD97
KGHKRFCRWRDCQCA

DMRT2

136

Q9Y5R5
GCEHICKKRLGTAWC

EGF

751

P01133
TCCLLCHRERKGWEE

FAM193B

81

Q96PV7
GHKRFCRWRDCACAK

DMRTA1

111

Q5VZB9
LGKNWHRFCLKCERC

CRIP3

21

Q6Q6R5
WHKECFVCTACRKQL

FHL2

181

Q14192
KHCCEWIKRISGECG

HAUS6

91

Q7Z4H7
CCFWCLEKFIKFLNR

SLC44A2

546

Q8IWA5
LGKDWHKFCLKCERC

CRIP2

21

P52943
FCCGTCHELKSFWEK

FAM240B

11

A0A1B0GVZ2
ASGLCCARHFWSKIC

DKK1

196

O94907
CWVDCGDAESRKLCK

PDIA5

81

Q14554
GFELHFWRKICRNCK

TES

31

Q9UGI8
WHLKHFCCFDCDSIL

TES

321

Q9UGI8
SERKKWIHCFEGVTC

GNAT2

206

P19087
WCTCHKKSLVETACR

AKR1E2

71

Q96JD6
ECHSCGRAFGEKWKL

ZIM3

196

Q96PE6
THTQEKLCECKDCWR

ZNF846

191

Q147U1
GESWLRKDCFHCTCL

MSMP

56

Q1L6U9
CEFCWLCMKEISDLH

RNF19A

326

Q9NV58
FKNNCELLVCDWCKH

SOBP

216

A7XYQ1
KITRCGHIFCWACIL

RNF10

236

Q8N5U6
LFCEKDGKALCWVCA

TRIM21

101

P19474
CKECRKAFSWLTCLL

ZNF442

546

Q9H7R0
CKECGKTFRWSSCLL

ZNF221

396

Q9UK13
CLFRHSWDKQCDRCH

ZCCHC7

296

Q8N3Z6
CDFCEAWVCHGRKCL

ZNF330

101

Q9Y3S2
ECGKSFRWASCLLKH

ZNF224

376

Q9NZL3
WCRDSEFRCKTKDSC

ZNF850

76

A8MQ14
LLWYCKAARCHACKR

ZMYM3

711

Q14202
CGDCHRVEAKDFWKA

NMD3

141

Q96D46