Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
Domain-

SEMA3F IFT140 TBL1Y PEX7 WDR97 TLE6 WDR24 TBL1X

2.76e-043339482.130.10.10
DomainWD40/YVTN_repeat-like_dom

SEMA3F IFT140 TBL1Y PEX7 WDR97 TLE6 WDR24 TBL1X

2.87e-04335948IPR015943
DomainWD40

IFT140 TBL1Y PEX7 WDR97 TLE6 WDR24 TBL1X

3.34e-04259947PF00400
DomainWD40

IFT140 TBL1Y PEX7 WDR97 TLE6 WDR24 TBL1X

4.10e-04268947SM00320
DomainWD40_repeat

IFT140 TBL1Y PEX7 WDR97 TLE6 WDR24 TBL1X

4.48e-04272947IPR001680
DomainWD_REPEATS_1

IFT140 TBL1Y PEX7 WDR97 TLE6 WDR24 TBL1X

5.10e-04278947PS00678
DomainP_proprotein

PCSK7 PCSK4

5.18e-047942PF01483
DomainS8_pro-domain

PCSK7 PCSK4

5.18e-047942IPR032815
DomainPrprotnconvertsP

PCSK7 PCSK4

5.18e-047942IPR002884
Domain-

PCSK7 PCSK4

5.18e-0479423.30.70.850
DomainS8_pro-domain

PCSK7 PCSK4

5.18e-047942PF16470
DomainWD_REPEATS_2

IFT140 TBL1Y PEX7 WDR97 TLE6 WDR24 TBL1X

5.21e-04279947PS50082
DomainWD_REPEATS_REGION

IFT140 TBL1Y PEX7 WDR97 TLE6 WDR24 TBL1X

5.21e-04279947PS50294
DomainWD40_repeat_dom

IFT140 TBL1Y PEX7 WDR97 TLE6 WDR24 TBL1X

7.53e-04297947IPR017986
DomainPeptidase_S8_His-AS

PCSK7 PCSK4

8.82e-049942IPR022398
DomainPeptidase_S8_Ser-AS

PCSK7 PCSK4

8.82e-049942IPR023828
DomainLisH

TBL1Y TBL1X

8.82e-049942PF08513
DomainPeptidase_S8_subtilisin-rel

PCSK7 PCSK4

1.10e-0310942IPR015500
DomainSUBTILASE_ASP

PCSK7 PCSK4

1.10e-0310942PS00136
DomainSUBTILASE_HIS

PCSK7 PCSK4

1.10e-0310942PS00137
DomainSUBTILASE_SER

PCSK7 PCSK4

1.10e-0310942PS00138
DomainEGF

STAB1 CELSR1 FCGBP TNR MUC4 SORL1

1.21e-03235946SM00181
Domain-

PCSK7 PCSK4

1.34e-03119423.40.50.200
DomainPeptidase_S8/S53_dom

PCSK7 PCSK4

1.34e-0311942IPR000209
DomainPeptidase_S8

PCSK7 PCSK4

1.34e-0311942PF00082
DomainWD40_repeat_CS

TBL1Y PEX7 WDR97 WDR24 TBL1X

1.44e-03164945IPR019775
DomainEGF-like_dom

STAB1 CELSR1 FCGBP TNR MUC4 SORL1

1.62e-03249946IPR000742
Domain-

SEMA3F TRIO HLA-DOA PILRA HLA-DPB1 PAPLN MYOM2 TNR EPB42 SORL1

1.84e-0366394102.60.40.10
DomainMHC_II_a/b_N

HLA-DOA HLA-DPB1

2.19e-0314942IPR014745
Domain-

HLA-DOA HLA-DPB1

2.19e-03149423.10.320.10
DomainSushi

CSMD3 CFB CSMD1

2.28e-0352943PF00084
DomainN2O_reductase_N

PEX7 TBL1X

2.52e-0315942IPR011045
DomainCCP

CSMD3 CFB CSMD1

2.54e-0354943SM00032
DomainSUSHI

CSMD3 CFB CSMD1

2.82e-0356943PS50923
DomainVWF_type-D

FCGBP MUC4

2.87e-0316942IPR001846
DomainVWFD

FCGBP MUC4

2.87e-0316942PS51233
DomainVWD

FCGBP MUC4

2.87e-0316942SM00216
DomainVWD

FCGBP MUC4

2.87e-0316942PF00094
DomainIg-like_fold

SEMA3F TRIO HLA-DOA PILRA HLA-DPB1 PAPLN MYOM2 TNR EPB42 SORL1

2.90e-037069410IPR013783
DomainSushi_SCR_CCP_dom

CSMD3 CFB CSMD1

2.97e-0357943IPR000436
DomainPropept_inh

PCSK7 PCSK4

3.24e-0317942IPR009020
DomainDH_1

TRIO PLEKHG7 PLEKHG3

3.94e-0363943PS00741
DomainRhoGEF

TRIO PLEKHG7 PLEKHG3

4.88e-0368943SM00325
Pubmed

X-linked late-onset sensorineural deafness caused by a deletion involving OA1 and a novel gene containing WD-40 repeats.

TBL1Y TBL1X

7.86e-06298210330347
Pubmed

Transducin β-like 1, X-linked and nuclear receptor co-repressor cooperatively augment the ligand-independent stimulation of TRH and TSHβ gene promoters by thyroid hormone receptors.

TBL1Y TBL1X

7.86e-06298229794369
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

SEMA3F ZNF384 TRIO KTI12 PAPLN HUWE1 ABCA7 FASN CELSR1 PI4KA NINL ZNF426 WDR24

1.38e-051105981335748872
Pubmed

Identification of two new members of the CSMD gene family.

CSMD3 CSMD1

2.35e-05398212906867
Pubmed

Tbl1 promotes Wnt-β-catenin signaling-induced degradation of the Tcf7l1 protein in mouse embryonic stem cells.

TBL1Y TBL1X

2.35e-05398238639717
Pubmed

Transducin β-like protein 1 recruits nuclear factor κB to the target gene promoter for transcriptional activation.

TBL1Y TBL1X

2.35e-05398221189284
Pubmed

The ubiquitin ligase Rnf6 regulates local LIM kinase 1 levels in axonal growth cones.

RNF6 RLIM

2.35e-05398216204183
Pubmed

Mutant Tbl1x male mice have a short life span and do not breed: unexpected findings.

TBL1Y TBL1X

2.35e-05398238381448
Pubmed

Contribution to Alzheimer's disease risk of rare variants in TREM2, SORL1, and ABCA7 in 1779 cases and 1273 controls.

ABCA7 SORL1

2.35e-05398228789839
Pubmed

Selective degradation of excess Ldb1 by Rnf12/RLIM confers proper Ldb1 expression levels and Xlim-1/Ldb1 stoichiometry in Xenopus organizer functions.

RNF6 RLIM

4.70e-05498212874135
Pubmed

MiR-486-3p was downregulated at microRNA profiling of adrenals of multiple endocrine neoplasia type 1 mice, and inhibited human adrenocortical carcinoma cell lines.

MEN1 FASN

4.70e-05498234285285
Pubmed

Transcriptional co-factor Transducin beta-like (TBL) 1 acts as a checkpoint in pancreatic cancer malignancy.

TBL1Y TBL1X

4.70e-05498226070712
Pubmed

Hepatic deficiency in transcriptional cofactor TBL1 promotes liver steatosis and hypertriglyceridemia.

TBL1Y TBL1X

7.82e-05598221459324
Pubmed

HLA-DPB1 and NFKBIL1 may confer the susceptibility to chronic thromboembolic pulmonary hypertension in the absence of deep vein thrombosis.

HLA-DPB1 NFKBIL1

7.82e-05598219165231
Pubmed

Exchange Factor TBL1 and Arginine Methyltransferase PRMT6 Cooperate in Protecting G Protein Pathway Suppressor 2 (GPS2) from Proteasomal Degradation.

TBL1Y TBL1X

7.82e-05598226070566
Pubmed

Association of Brain DNA methylation in SORL1, ABCA7, HLA-DRB5, SLC24A4, and BIN1 with pathological diagnosis of Alzheimer disease.

ABCA7 SORL1

7.82e-05598225365775
Pubmed

Distinct roles for CARMIL isoforms in cell migration.

TRIO CARMIL1

7.82e-05598219846667
Pubmed

Proprotein convertase expression and localization in epidermis: evidence for multiple roles and substrates.

FLG PCSK7

7.82e-05598211380615
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

EXPH5 DHX37 CARMIL1 MAP3K4 KIF2B FGB MYOM2 MUC4

8.40e-0549798836774506
Pubmed

Circular rapid amplification of cDNA ends for high-throughput extension cloning of partial genes.

ADGRV1 ABCA7 FCGBP CSMD1

9.62e-058498415203218
Pubmed

Structure of the MeCP2-TBLR1 complex reveals a molecular basis for Rett syndrome and related disorders.

TBL1Y TBL1X

1.17e-04698228348241
Pubmed

Sequential genome-wide CRISPR-Cas9 screens identify genes regulating cell-surface expression of tetraspanins.

NOL9 STAB1 GSE1 MLC1 PI4KA RLIM NINL PCSK7 CSMD1 WDR24

1.22e-04832981036724073
Pubmed

Proteolytic processing in the secretory pathway.

PCSK7 PCSK4

1.64e-04798210409610
Pubmed

Mapping of the murine tbl1 gene reveals a new rearrangement between mouse and human X Chromosomes.

TBL1Y TBL1X

1.64e-0479829880679
Pubmed

The family of subtilisin/kexin like pro-protein and pro-hormone convertases: divergent or shared functions.

PCSK7 PCSK4

1.64e-0479827819324
Pubmed

Unusual chromatin status and organization of the inactive X chromosome in murine trophoblast giant cells.

HUWE1 RLIM

1.64e-04798223362347
Pubmed

MEGF10 is a mammalian ortholog of CED-1 that interacts with clathrin assembly protein complex 2 medium chain and induces large vacuole formation.

TFAP2B AP2M1

1.64e-04798217643423
Pubmed

Zbtb7c is a molecular 'off' and 'on' switch of Mmp gene transcription.

TBL1Y TBL1X

1.64e-04798227646874
Pubmed

The nuclear receptor corepressor deacetylase activating domain is essential for repression by thyroid hormone receptor.

TBL1Y TBL1X

1.64e-04798215695367
Pubmed

Regulation of bone morphogenetic protein activity by pro domains and proprotein convertases.

PCSK7 PCSK4

2.18e-0489829885250
Pubmed

Rett syndrome mutations abolish the interaction of MeCP2 with the NCoR/SMRT co-repressor.

TBL1Y TBL1X

2.18e-04898223770565
Pubmed

A SUMOylation-dependent pathway mediates transrepression of inflammatory response genes by PPAR-gamma.

TBL1Y TBL1X

2.18e-04898216127449
Pubmed

Interaction of amyotrophic lateral sclerosis/frontotemporal lobar degeneration-associated fused-in-sarcoma with proteins involved in metabolic and protein degradation pathways.

DBF4B KLHL5 EEF1G FASN GIMAP8

2.69e-0420198525192599
Pubmed

Refining the association of MHC with multiple sclerosis in African Americans.

HLA-DPB1 CFB

2.79e-04998220466734
Pubmed

The activation and physiological functions of the proprotein convertases.

PCSK7 PCSK4

2.79e-04998218343183
Pubmed

The prohormone theory and the proprotein convertases: it is all about serendipity.

PCSK7 PCSK4

2.79e-04998221805236
Pubmed

The proprotein convertases, 20 years later.

PCSK7 PCSK4

2.79e-04998221805237
Pubmed

The biology and therapeutic targeting of the proprotein convertases.

PCSK7 PCSK4

2.79e-04998222679642
Pubmed

The multifaceted proprotein convertases: their unique, redundant, complementary, and opposite functions.

PCSK7 PCSK4

2.79e-04998223775089
Pubmed

SPC4, SPC6, and the novel protease SPC7 are coexpressed with bone morphogenetic proteins at distinct sites during embryogenesis.

PCSK7 PCSK4

2.79e-0499828698813
Pubmed

Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.

ZNF384 HLA-DPB1 EXPH5 SCYL1 ANKS1B PEX7 ACYP1 RNF6 MYOM2 CSMD1 PLK4 ZNF426

2.83e-041293981215342556
Pubmed

HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.

SEMA3F FLG DHX37 DBF4B DNAH2 SCYL1 NOL9 FASN PI4KA

2.85e-0475498935906200
Pubmed

Expression and transient nuclear translocation of proprotein convertase 1 (PC1) during mouse preimplantation embryonic development.

PCSK7 PCSK4

3.48e-041098216163737
Pubmed

A corepressor/coactivator exchange complex required for transcriptional activation by nuclear receptors and other regulated transcription factors.

TBL1Y TBL1X

3.48e-041098214980219
Pubmed

Association of granulomatosis with polyangiitis (Wegener's) with HLA-DPB1*04 and SEMA6A gene variants: evidence from genome-wide analysis.

HLA-DOA HLA-DPB1

5.09e-041298223740775
Pubmed

HIV-1 Nef impairs MHC class II antigen presentation and surface expression.

HLA-DOA HLA-DPB1

5.09e-041298211593029
Pubmed

Down-modulation of mature major histocompatibility complex class II and up-regulation of invariant chain cell surface expression are well-conserved functions of human and simian immunodeficiency virus nef alleles.

HLA-DOA HLA-DPB1

5.09e-041298212970439
Pubmed

Insulin receptor substrate-4 interacts with ubiquitin-specific protease 18 to activate the Jak/STAT signaling pathway.

HUWE1 FASN

6.01e-041398229285303
Pubmed

HLA class II antigens and the HIV envelope glycoprotein gp120 bind to the same face of CD4.

HLA-DOA HLA-DPB1

7.00e-04149827512597
Pubmed

Class III myosins shape the auditory hair bundles by limiting microvilli and stereocilia growth.

ESPNL ADGRV1

7.00e-041498226754646
Pubmed

Interaction of CD4 with HLA class II antigens and HIV gp120.

HLA-DOA HLA-DPB1

7.00e-04149821869305
Pubmed

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

TBL1Y NOL9 HUWE1 MEN1 FASN GSE1 PI4KA TBL1X SORL1

7.16e-0485798925609649
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

GPBP1 TRIO EXPH5 CARMIL1 PLEKHG3 PI4KA NR3C2 PLK4 USP6NL

7.40e-0486198936931259
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

IFT140 TRIM35 ADGRV1 CAPN10 STAB1 NINL USP6NL

7.60e-0452998714621295
Pubmed

Proteomics analysis of the interactome of N-myc downstream regulated gene 1 and its interactions with the androgen response program in prostate cancer cells.

EEF1G FASN AP2M1

7.62e-046398317220478
Pubmed

HIV-1 envelope protein is expressed on the surface of infected cells before its processing and presentation to class II-restricted T lymphocytes.

HLA-DOA HLA-DPB1

8.06e-04159828376762
Pubmed

Envelope glycoproteins of HIV-1 interfere with T-cell-dependent B cell differentiation: role of CD4-MHC class II interaction in the effector phase of T cell help.

HLA-DOA HLA-DPB1

8.06e-04159828168144
Pubmed

Strategy for identifying dendritic cell-processed CD4+ T cell epitopes from the HIV gag p24 protein.

HLA-DOA HLA-DPB1

8.06e-041598222860026
Pubmed

Endocytosis of endogenously synthesized HIV-1 envelope protein. Mechanism and role in processing for association with class II MHC.

HLA-DOA HLA-DPB1

8.06e-04159827602119
Pubmed

HIV-gp120 can block CD4-class II MHC-mediated adhesion.

HLA-DOA HLA-DPB1

8.06e-04159821967269
Pubmed

The enhanced immune response to the HIV gp160/LAMP chimeric gene product targeted to the lysosome membrane protein trafficking pathway.

HLA-DOA HLA-DPB1

8.06e-04159829079699
Pubmed

AIDS and related syndromes as a viral-induced autoimmune disease of the immune system: an anti-MHC II disorder. Therapeutic implications.

HLA-DOA HLA-DPB1

8.06e-04159823489470
Pubmed

Efficient incorporation of HLA class II onto human immunodeficiency virus type 1 requires envelope glycoprotein packaging.

HLA-DOA HLA-DPB1

8.06e-041598210729169
Pubmed

Inhibition of CD4+ T cell function by the HIV envelope protein, gp120.

HLA-DOA HLA-DPB1

9.19e-04169822846691
Pubmed

Identification and structural analysis of residues in the V1 region of CD4 involved in interaction with human immunodeficiency virus envelope glycoprotein gp120 and class II major histocompatibility complex molecules.

HLA-DOA HLA-DPB1

9.19e-04169821978941
Pubmed

Identification of human CD4 residues affecting class II MHC versus HIV-1 gp120 binding.

HLA-DOA HLA-DPB1

9.19e-04169822543930
Pubmed

Human immunodeficiency virus type 1 Vpu protein interacts with CD74 and modulates major histocompatibility complex class II presentation.

HLA-DOA HLA-DPB1

9.19e-041698217959659
Pubmed

Candidate genes and their regulatory elements: alcohol preference and tolerance.

TBL1Y TBL1X

1.04e-031798216783646
Pubmed

Nef proteins from simian immunodeficiency virus-infected chimpanzees interact with p21-activated kinase 2 and modulate cell surface expression of various human receptors.

HLA-DOA HLA-DPB1

1.04e-031798215194762
Pubmed

The activity of Nef on HIV-1 infectivity.

HLA-DOA HLA-DPB1

1.04e-031798224904546
Pubmed

Competitive binding of E3 ligases TRIM26 and WWP2 controls SOX2 in glioblastoma.

CFB EEF1G CELSR1 AP2M1 PLEKHG3 PI4KA MARF1 FGB

1.11e-0373298834732716
Pubmed

Promoting anti-tumor immunity by targeting TMUB1 to modulate PD-L1 polyubiquitination and glycosylation.

HUWE1 FASN PI4KA

1.12e-037298336376293
Pubmed

Genetic variants of the HLA-A, HLA-B and AIF1 loci show independent associations with type 1 diabetes in Norwegian families.

CFB NFKBIL1

1.17e-031898218987644
Pubmed

HIV-1 Nef promotes endocytosis of cell surface MHC class II molecules via a constitutive pathway.

HLA-DOA HLA-DPB1

1.17e-031898219620308
Pubmed

Several loci in the HLA class III region are associated with T1D risk after adjusting for DRB1-DQB1.

CFB NFKBIL1

1.17e-031898219143814
Pubmed

Reciprocal modulation of transcriptional activities between HIV-1 Tat and MHC class II transactivator CIITA.

HLA-DOA HLA-DPB1

1.17e-031898211118314
Pubmed

Tat competes with CIITA for the binding to P-TEFb and blocks the expression of MHC class II genes in HIV infection.

HLA-DOA HLA-DPB1

1.17e-031898210661406
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

FLG IFT140 CARMIL1 SCYL1 AP2M1 NEK5 NFKBIL1 MARF1 NINL WDR24 SORL1

1.24e-031321981127173435
Pubmed

PGE2 through the EP4 receptor controls smooth muscle gene expression patterns in the ductus arteriosus critical for remodeling at birth.

NPR3 TFAP2B

1.30e-031998222342504
Pubmed

Local protease signaling contributes to neural tube closure in the mouse embryo.

CFB CTRL

1.44e-032098220152175
Pubmed

Nef performance in macrophages: the master orchestrator of viral persistence and spread.

HLA-DOA HLA-DPB1

1.44e-032098222103834
Pubmed

HIV gp120 inhibits T cell activation by interfering with expression of costimulatory molecules CD40 ligand and CD80 (B71).

HLA-DOA HLA-DPB1

1.44e-03209827541827
Pubmed

HIV-1 gp120 modulates the immunological function and expression of accessory and co-stimulatory molecules of monocyte-derived dendritic cells.

HLA-DOA HLA-DPB1

1.44e-032098212427289
Pubmed

High-density SNP screening of the major histocompatibility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions.

HLA-DOA HLA-DPB1 CFB NFKBIL1

1.55e-0317598419851445
Pubmed

HIV-1 Gag-virus-like particles induce natural killer cell immune responses via activation and maturation of dendritic cells.

HLA-DOA HLA-DPB1

1.59e-032198221778700
Pubmed

HIV-1 gp41 binding proteins and antibodies to gp41 could inhibit enhancement of human Raji cell MHC class I and II expression by gp41.

HLA-DOA HLA-DPB1

1.59e-03219828084338
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

TRIO TBL1Y ANKS1B NOL9 HUWE1 PI4KA SPHKAP TNR TBL1X

1.61e-0396398928671696
Pubmed

Genetic variants associated with disordered eating.

FLG SPHKAP CSMD1

1.69e-038398323568457
Pubmed

Cytosolic quality control of mislocalized proteins requires RNF126 recruitment to Bag6.

HUWE1 RLIM

1.75e-032298224981174
Pubmed

The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.

DBF4B ESPNL PAPLN MAMDC4 C16orf89 GFOD2 CD163L1 CSMD1 PCSK4

1.88e-0398598912975309
Pubmed

Role of HIV-1 Nef protein for virus replication in vitro.

HLA-DOA HLA-DPB1

1.91e-032398219770068
Pubmed

Comparative interactome analysis of α-arrestin families in human and Drosophila.

HUWE1 MAGED4 PI4KA NFKBIL1 RLIM

1.96e-0331398538270169
Pubmed

Human immunodeficiency virus type-1 (HIV-1) Pr55gag virus-like particles are potent activators of human monocytes.

HLA-DOA HLA-DPB1

2.08e-032498218945465
Pubmed

Function of the Src-family kinases, Lck and Fyn, in T-cell development and activation.

HLA-DOA HLA-DPB1

2.08e-032498215489916
Pubmed

Editorial. Nef: a notorious enigmatic factor in HIV biology.

HLA-DOA HLA-DPB1

2.08e-032498222175768
Pubmed

Barx2 functions through distinct corepressor classes to regulate hair follicle remodeling.

TBL1Y TBL1X

2.08e-032498215728386
Pubmed

Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons.

RASGRP4 KLHL5 EEF1G PI4KA MARF1

2.22e-0332298526514267
Pubmed

HIV accessory proteins and surviving the host cell.

HLA-DOA HLA-DPB1

2.26e-032598216091223
Pubmed

In vivo validation of late-onset Alzheimer's disease genetic risk factors.

ABCA7 SORL1

2.26e-032598238687251
Pubmed

Adapters in lymphocyte signaling.

HLA-DOA HLA-DPB1

2.44e-032698211827988
Cytoband4q28

FGB PLK4

1.61e-0499824q28
Cytoband6p21.3

HLA-DOA HLA-DPB1 CFB NFKBIL1

2.08e-032509846p21.3
GeneFamilyWD repeat domain containing

IFT140 TBL1Y PEX7 WDR97 TLE6 WDR24 TBL1X

5.65e-05262687362
GeneFamilyProprotein convertase subtilisin/kexin family

PCSK7 PCSK4

4.93e-049682973
GeneFamilyHyalectan proteoglycans|V-set domain containing|Sushi domain containing|C-type lectin domain containing

CSMD3 CFB CSMD1

1.29e-03576831179
GeneFamilyFibrinogen C domain containing

FGB TNR

3.95e-0325682554
GeneFamilyC2-set domain containing|Immunoglobulin like domain containing|Scavenger receptors

STAB1 CD163L1

4.60e-03276821253
CoexpressionGSE3982_NKCELL_VS_TH1_UP

NPR3 PILRA EXPH5 DNAH2 PEX7 ADGRV1 ADARB1 GSE1 PCSK7

4.72e-08195979M5593
ToppCell3'_v3-GI_small-bowel-Lymphocytic_B-Memory_B_cells|GI_small-bowel / Manually curated celltypes from each tissue

HLA-DOA HLA-DPB1 PLEKHG7 ESPNL CELSR1 TNR

1.96e-061689868e025bb0541746e232b77ac0e31412ae71420c47
ToppCell3'_v3-GI_small-bowel-Lymphocytic_B|GI_small-bowel / Manually curated celltypes from each tissue

HLA-DOA HLA-DPB1 PLEKHG7 ESPNL CELSR1 TNR

1.96e-061689865535c1b8b7fde7b59a1bc0580cebdfa963aa1c39
ToppCell(07)_Ionocytes-(2)_GFP_FOXI1|(07)_Ionocytes / shred by cell type by condition

NFKBIZ KLHL5 FASN RLIM MUC4 SORL1

2.25e-061729865776b638b845d054f6e884e7df0412477f48517d
ToppCell10x5'-Liver-Lymphocytic_B-Memory_B_cells|Liver / Manually curated celltypes from each tissue

HLA-DOA HLA-DPB1 PLEKHG7 EEF1G CELSR1 USP6NL

3.02e-06181986a9f4df288c34e3b2b6ed861ac6cda970c3ee08b1
ToppCell3'-Child04-06-SmallIntestine-Hematopoietic-Myeloid-Macrophages|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HLA-DOA PILRA HLA-DPB1 STAB1 GIMAP8 CD163L1

3.22e-0618398692d5a61b57851090eba558f19e2a7010043eff81
ToppCell3'_v3-bone_marrow-Lymphocytic_B-Memory_B_cells|bone_marrow / Manually curated celltypes from each tissue

HLA-DOA HLA-DPB1 PLEKHG7 ESPNL TNR USP6NL

3.32e-06184986ffc9eec123de34a4f17ed27fe4f0a1b3cb84697f
ToppCellCOPD-Lymphoid-B|Lymphoid / Disease state, Lineage and Cell class

TRIO HLA-DPB1 PLEKHG7 CARMIL1 KLHL5 USP6NL

4.00e-061909861e85ee686ff6dd27c69415d524d54fa825b1daad
ToppCellproximal-Hematologic-Platelet/Megakaryocyte|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

TRIO PLEKHG7 SPTBN5 WDR97 PI4KA PLK4

4.24e-06192986522d1bb15edf1d6006b80289bd3baadb99584ae8
ToppCellproximal-3-Hematologic-Platelet/Megakaryocyte|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

TRIO PLEKHG7 SPTBN5 WDR97 PI4KA PLK4

4.24e-06192986f5f83dec37dff32a0c471cb05d23d13b0b0ad0c9
ToppCellproximal-Hematologic-Platelet/Megakaryocyte-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

TRIO PLEKHG7 SPTBN5 WDR97 PI4KA PLK4

4.24e-0619298657899a905ca3e336bb7f31edc6418a2546b9891a
ToppCellBronchial-10x5prime-Immune_Myeloid-Macrophage_other-Macro_AW_CX3CR1|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

HLA-DOA HLA-DPB1 STAB1 FCGBP PLK4 SORL1

4.78e-06196986b15812354128c12a588d79ef449d787e74835f3b
ToppCell(3)_Macrophage_MARCOneg|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

HLA-DOA PILRA STAB1 FCGBP CD163L1 NFKBIL1

4.92e-06197986b0ee2ce1179b60b4542559acb300a34295277dbc
ToppCell5'-GW_trimst-2-LargeIntestine-Hematopoietic-Myeloid|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RASGRP4 HLA-DOA PILRA HLA-DPB1 STAB1 CD163L1

5.21e-06199986f34c15df58fbdc6c90e30800e26fabbf828ad10b
ToppCellCOVID-19_Mild|World / 5 Neutrophil clusters in COVID-19 patients

CCDC168 ADGRV1 CELSR1 MARF1 CSMD1

2.17e-051529852ff0980dfd8d430cca14649151d856edef115720
ToppCellfacs-Lung-Endomucin_-18m-Myeloid-Neutrophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASGRP4 PILRA ABCA7 PLEKHG3 SORL1

2.86e-05161985e227f7b711475624cf80e77f235b1783d88d57b4
ToppCellfacs-Lung-Endomucin_-18m-Myeloid-neutrophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASGRP4 PILRA ABCA7 PLEKHG3 SORL1

2.86e-051619858280a029026c272cae9649b27575831b0dd4e242
ToppCellPBMC-Severe-Lymphocyte-B-B_cell-B_naive-B_naive-1|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TRIO HLA-DOA HLA-DPB1 CELSR1 MARF1

3.22e-05165985fead3f2032f8fa5f7f0159a4434989b3d65debbb
ToppCellCerebellum-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Lrg1_(Lrg1)--|Cerebellum / BrainAtlas - Mouse McCarroll V32

RASGRP4 PAPLN CFB GIMAP8

3.41e-05839843aa95bf2d8ac37e648037faf3d54ebb243a4fde1
ToppCellCerebellum-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Lrg1_(Lrg1)-|Cerebellum / BrainAtlas - Mouse McCarroll V32

RASGRP4 PAPLN CFB GIMAP8

3.41e-058398470804dd63221dd5ed26068ec1b50f11875abbc50
ToppCellCerebellum-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Lrg1_(Lrg1)|Cerebellum / BrainAtlas - Mouse McCarroll V32

RASGRP4 PAPLN CFB GIMAP8

3.41e-0583984c1818411438f53aec76afead5c8caab701b95d39
ToppCellCerebellum-Endothelial-ENDOTHELIAL_STALK-Flt1_2|Cerebellum / BrainAtlas - Mouse McCarroll V32

RASGRP4 PAPLN CFB GIMAP8

3.41e-05839841e7af8aaa20b4c2a77cf2f330113db0faa9d483c
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.1.3|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NFKBIZ CFB FCGBP CLCN1 WDR97

3.41e-051679858fede587572d465cb63f7828141a574185bbb819
ToppCell3'_v3-blood-Lymphocytic_B-ABC_aged-B_memory|blood / Manually curated celltypes from each tissue

IFT140 HLA-DPB1 PLEKHG7 CARMIL1 WDR97

3.51e-051689852ce1a30feb2704a9516d1dab161a26cb0555abb5
ToppCellAdult-Endothelial-endothelial_cell_of_artery-D122|Adult / Lineage, Cell type, age group and donor

SEMA3F NPR3 DNAJC18 GIMAP8 CSMD1

3.51e-051689858c3e1e45b422813bcdfa4273b1167db649a312f5
ToppCelldroplet-Liver-LIVER_NPC-30m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FCGBP NINL CSMD1 TNR MUC4

3.71e-05170985a121e10099faaeb60251eec162f38caf7c4238c2
ToppCellControl-Myeloid-MoAM2,_CCL18|Myeloid / Condition, Lineage and Cell class

ADARB1 STAB1 CELSR1 CD163L1 NINL

4.50e-05177985470f54fe2b21c7350ea471e02039461a3808f700
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

KCNV2 NFKBIZ MTHFD2L NR3C2 MUC4

5.00e-05181985576da14ab3107f89e1f44a4a439d1bef5bb42370
ToppCell3'-Child04-06-SmallIntestine-Hematopoietic-Myeloid-Monocytes|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PILRA HLA-DPB1 NFKBIZ STAB1 SPTBN5

5.55e-0518598500a991e63e9ac6de3f48a96e3be6073f90cbb442
ToppCellwk_15-18-Epithelial-Distal_epithelial_progenitor-epi-tip_intermediate|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

EXPH5 MAMDC4 CELSR1 WDR97 NEK5

5.55e-05185985636505a3d96f75d951ab42bcf8af6ae07abc732d
ToppCell3'_v3-blood-Lymphocytic_B|blood / Manually curated celltypes from each tissue

HLA-DOA HLA-DPB1 PLEKHG7 CARMIL1 USP6NL

5.69e-051869855624b1fc7eab9f505588fcc86a24d14f8bcbfef7
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ADGRV1 CSMD3 STAB1 CSMD1 TBL1X

5.69e-0518698523b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCelldroplet-Lung-3m-Endothelial-venous_endothelial-vein_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SEMA3F NPR3 C16orf89 KLHL5 FGB

5.84e-051879853827fa80e558b642f3e0036f5ee1a8b69f437e30
ToppCelldroplet-Lung-3m-Endothelial-venous_endothelial-vein_endothelial_cell-vein_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SEMA3F NPR3 C16orf89 KLHL5 FGB

5.84e-051879851bf696eb03422ea507d3efe58dda1d442a65225d
ToppCelldroplet-Lung-3m-Endothelial-venous_endothelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SEMA3F NPR3 C16orf89 KLHL5 FGB

5.84e-05187985ebe4d1216cc0d4c079b413d5a5460cfd3a4af922
ToppCellIPF-Lymphoid-B|Lymphoid / Disease state, Lineage and Cell class

TRIO HLA-DPB1 PLEKHG7 CARMIL1 USP6NL

5.84e-05187985af1327559f7e01bec070881cae52834917c3da65
ToppCellCOVID-19-Epithelial_cells|COVID-19 / group, cell type (main and fine annotations)

EXPH5 ADGRV1 FASN CELSR1 MUC4

5.99e-05188985c9cdee6f8d42ee69f5fb335f25084603c511bd29
ToppCellPCW_13-14-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

EXPH5 ADGRV1 CELSR1 FCGBP NR3C2

5.99e-051889850d86044bc340e3efb90d0022dd299873639d831c
ToppCell10x5'-GI_small-bowel-Lymphocytic_B-Memory_B_cells|GI_small-bowel / Manually curated celltypes from each tissue

HLA-DOA HLA-DPB1 PLEKHG7 TNR USP6NL

5.99e-05188985ab1384e6f71053946368502282aeebf1ba92d33e
ToppCell10x5'-blood-Lymphocytic_B-Memory_B_cells|blood / Manually curated celltypes from each tissue

HLA-DOA HLA-DPB1 PLEKHG7 ESPNL USP6NL

6.14e-051899858aa65ffc396ccc5e86a6d38b99a2d51c34c9b6d2
ToppCellCOVID_vent-Lymphocytic-B_cell|COVID_vent / Disease condition, Lineage, Cell class and subclass

TRIO HLA-DOA HLA-DPB1 CELSR1 USP6NL

6.30e-0519098540b5e9e8f8fd8d84cb5b43e67b49267082348e9f
ToppCellCOVID_vent-Lymphocytic-B_cell-|COVID_vent / Disease condition, Lineage, Cell class and subclass

TRIO HLA-DOA HLA-DPB1 CELSR1 USP6NL

6.30e-05190985a37a32dc1b931562a6660074e19d5598efc65284
ToppCell368C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)|368C / Donor, Lineage, Cell class and subclass (all cells)

HLA-DOA HLA-DPB1 STAB1 FCGBP CD163L1

6.30e-05190985cbba3d94a4c3e0b0d14f3b7c60dba5d6e097c5e3
ToppCell10x5'-GI_large-bowel-Lymphocytic_B-Memory_B_cells|GI_large-bowel / Manually curated celltypes from each tissue

HLA-DPB1 PLEKHG7 ESPNL EEF1G USP6NL

6.61e-0519298531f7245bce79969674a775ecf175e7c6af68b503
ToppCellNS-moderate-d_0-4|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

EXPH5 DNAH2 ADGRV1 CELSR1 NEK5

6.78e-05193985ea345d34440b25f65358a53dc72831998d1c3620
ToppCelldistal-Hematologic-IGSF21+_Dendritic-1|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

HLA-DOA HLA-DPB1 STAB1 FCGBP CD163L1

6.78e-0519398548ce11778252ae2ef902b30816061b59a3c81695
ToppCelldistal-1-Hematologic-IGSF21+_Dendritic|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

HLA-DOA HLA-DPB1 STAB1 FCGBP CD163L1

6.95e-05194985f30c866e5f41ee79bdc6b6e08af962d62b199835
ToppCellControl-Epithelial-ATII|Epithelial / Disease state, Lineage and Cell class

HLA-DPB1 NFKBIZ C16orf89 FASN NR3C2

6.95e-05194985a01de094f7bfd099bcbb2f94224690a2efb887b4
ToppCell3'-GW_trimst-2-SmallIntestine-Hematopoietic-Myeloid-Macrophages|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HLA-DOA PILRA HLA-DPB1 STAB1 CD163L1

6.95e-0519498544a90be1d2b2ae08f8c523bee65dd1e536ec0f95
ToppCell3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)-Goblet_(subsegmental)_L.0.4.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFB C16orf89 CELSR1 FCGBP SORL1

7.12e-051959852a9a36df1dbc4eac77a8ddbe939ec8a8d6c41464
ToppCell15-Airway-Immune-Hematopoietic,_Macrophage|Airway / Age, Tissue, Lineage and Cell class

RASGRP4 HLA-DOA PILRA HLA-DPB1 STAB1

7.12e-05195985705aa5442c61d5fdc0aafb2ad40b8c9d2dc566c6
ToppCellwk_20-22-Hematologic-Myeloid-S100A12-lo_cla._mono.|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

RASGRP4 PILRA HLA-DPB1 STAB1 FCGBP

7.12e-0519598566273af9882f829b6fc0e20f03f3412294d37c26
ToppCell5'-Adult-SmallIntestine-Hematopoietic-Myeloid|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HLA-DOA PILRA HLA-DPB1 STAB1 CD163L1

7.12e-05195985f289a44010788853d7726d4b5aa75f3c62186c08
ToppCell3'-Pediatric_IBD-SmallIntestine-Hematopoietic-Myeloid-LYVE1+_Macrophage|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HLA-DOA PILRA HLA-DPB1 STAB1 CD163L1

7.12e-05195985c16479a10f5ca2e89aea1742dbc5cc4dc9f3ea88
ToppCellfacs-Aorta-Heart-3m-Endothelial|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA3F NPR3 STAB1 C16orf89 GIMAP8

7.12e-051959858493f2f60fc356af28b9c0e287d4cd8c8899c081
ToppCell3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFB C16orf89 CELSR1 FCGBP SORL1

7.12e-05195985576142b4e75457c0973051bccc4163bd624496af
ToppCell3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFB C16orf89 CELSR1 FCGBP SORL1

7.12e-051959858f151066ad3ebd9661ea0b733f03c2ce1518f9ad
ToppCellfacs-Aorta-Heart-3m-Endothelial-aorta_endothelial_cell|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA3F NPR3 STAB1 C16orf89 GIMAP8

7.12e-051959853969b8d5fcec8ef1831531a781f7bbcebab5a4ba
ToppCellfacs-Aorta-Heart-3m-Endothelial-aortic_endothelial_cell|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA3F NPR3 STAB1 C16orf89 GIMAP8

7.12e-051959855e5ca7bd94c9e924ed76f7ccac199be745d4c4eb
ToppCell356C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)|356C / Donor, Lineage, Cell class and subclass (all cells)

PILRA HLA-DPB1 STAB1 FCGBP CD163L1

7.12e-051959859231e929657542b78a6480d44402866511129c7f
ToppCellSecretory|World / shred by cell class for bronchial biopsy

PLEKHG7 CFB FCGBP MUC4 SORL1

7.12e-0519598552f8281fe0df67cec3faa780a23ed6343ed5a6ba
ToppCellASK454-Endothelial-Endothelium|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq

SEMA3F NPR3 DNAJC18 GIMAP8 GFOD2

7.29e-051969852b777a2026b56839112fd179f2db482c49f4594a
ToppCellMonocytes-IL1B+_Monocytes|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

RASGRP4 PILRA HLA-DPB1 STAB1 GIMAP8

7.29e-051969857bc0735d324ac5a1661434cda4116ddd58296730
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_B-Memory_B_cells|lymph-node_spleen / Manually curated celltypes from each tissue

HLA-DOA HLA-DPB1 PLEKHG7 CARMIL1 USP6NL

7.29e-05196985c450cd6b799932f5cce8326d1079114abeb71e95
ToppCellILEUM-non-inflamed-(3)_Resident_macrophages|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

HLA-DOA PILRA STAB1 CD163L1 NFKBIL1

7.47e-051979853af24354b6a93c7d105b9fa6549cf215107b9203
ToppCell3'-GW_trimst-2-SmallIntestine-Hematopoietic-Myeloid|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HLA-DOA PILRA HLA-DPB1 STAB1 CD163L1

7.47e-0519798509a2c0c0f9c2442743414236c2d5c1f27be66e4c
ToppCell5'-GW_trimst-2-LargeIntestine-Hematopoietic-Myeloid-Macrophages|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HLA-DOA PILRA HLA-DPB1 STAB1 CD163L1

7.47e-0519798510190b877bf46ba2163d203df9dd3b498c66e52f
ToppCellNon-neuronal-Non-dividing-Radial_Glia-tRG|World / Primary Cells by Cluster

NFKBIZ ADGRV1 CELSR1 MLC1 TBL1X

7.47e-0519798561749ccafeb938c310cff1de5ff924a1c794325a
ToppCellNon-neuronal-Non-dividing-Radial_Glia-tRG-25|World / Primary Cells by Cluster

NFKBIZ ADGRV1 CELSR1 MLC1 TBL1X

7.47e-051979859d4ffa3680f92c91d0a081f9a8ec5ebfec6bdcf6
ToppCell5'-GW_trimst-2-SmallIntestine-Hematopoietic-Myeloid|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HLA-DOA PILRA HLA-DPB1 STAB1 CD163L1

7.65e-05198985dbae6a58cb3ce8612755fbdba6194b70b35f258a
ToppCell3'-Child09-12-SmallIntestine-Hematopoietic-Myeloid|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HLA-DOA PILRA HLA-DPB1 STAB1 CD163L1

7.65e-05198985af682919a874d60f579e854c274dc47063015ea9
ToppCell5'-GW_trimst-2-SmallIntestine-Hematopoietic|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HLA-DOA PILRA HLA-DPB1 STAB1 CD163L1

7.65e-0519898541e8a7894f52f3a5f8f24575b3f6e205429489b2
ToppCellTracheal-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Duct|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

EXPH5 ANKS1B CFB C16orf89 MUC4

7.83e-05199985527aae1d9d37a50deefc01fc0c064a53673681bd
ToppCell5'-GW_trimst-2-SmallIntestine-Hematopoietic-Myeloid-Macrophages|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HLA-DOA PILRA HLA-DPB1 STAB1 CD163L1

7.83e-051999859df2c79904dacf029ec9df1f1cde72d871189a82
ToppCell5'-GW_trimst-2-LargeIntestine-Hematopoietic|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HLA-DOA PILRA HLA-DPB1 STAB1 CD163L1

7.83e-051999855ceeed92f831d068ff4bb3994f420002338330e7
ToppCell5'-Adult-LargeIntestine-Hematopoietic-Myeloid|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RASGRP4 PILRA HLA-DPB1 STAB1 CD163L1

7.83e-05199985a4785c1921a3de18a9190e4d674ede6a90f80004
ToppCellwk_20-22-Hematologic-Myeloid|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

RASGRP4 PILRA HLA-DPB1 STAB1 CD163L1

7.83e-051999850740166c51ce63edf83c4b98fce057f1440116d7
ToppCellwk_20-22-Hematologic|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

RASGRP4 PILRA HLA-DPB1 STAB1 CD163L1

7.83e-05199985f360c75e169536578550bed79461a5947e2472b1
ToppCelltumor_Lymph_Node_/_Brain-Myeloid_cells-mo-Mac|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

HLA-DOA PILRA HLA-DPB1 STAB1 FCGBP

8.02e-05200985b3f4eb45545f1632dc62f942756a6b81397c18c1
ToppCellParenchymal-10x3prime_v2-Immune_Myeloid-Macrophage_other-Macrophage_intravascular|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

HLA-DOA PILRA HLA-DPB1 STAB1 CD163L1

8.02e-052009854b4df0fe47498310d94448b8a289e58e4f5b5aa8
ToppCellTracheal-NucSeq-Immune_Myeloid-Monocytic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

RASGRP4 PILRA HLA-DPB1 STAB1 GIMAP8

8.02e-0520098548ce43a27e78b2883e588e1a63fa5352c2deeeb7
ToppCell356C-Epithelial_cells-Epithelial-H_(AT1)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

COQ6 MAP3K4 MUC4 ZNF426

1.34e-0411898408bdf7bc3c9dcbc0f690658fe14e6cc4b9581698
ToppCell356C-Epithelial_cells-Epithelial-H_(AT1)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

COQ6 MAP3K4 MUC4 ZNF426

1.34e-041189843b077ad5c68c01b3fcc93f203cb130bb90705af9
ToppCelldroplet-Marrow-nan-21m-Lymphocytic-immature_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PILRA MAMDC4 FGB NINL

1.39e-04119984aa3860c8d25c85baa79a0b6637bce2e269adfcc2
ToppCellCOVID-19_Mild-Neu_3|World / 5 Neutrophil clusters in COVID-19 patients

EXPH5 CCDC168 CSMD3 CSMD1

1.53e-041229842aa9cfadab70312882ae679e3788fc7ab996c0f3
ToppCellHippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Pvrl3|Hippocampus / BrainAtlas - Mouse McCarroll V32

EXPH5 FCGBP CEACAM18 MYOM2

1.78e-041279849bc55cb9f4bddb274930784d12a83b9dceb35cb7
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Nonmucinous_Lepidic_Adenocarcinoma-7|TCGA-Lung / Sample_Type by Project: Shred V9

IFT140 DNAH2 C16orf89 NEK5

1.95e-0413098417a4ee699adfa265335b1abfe6cb0f3f7c93362b
ToppCellPBMC-Severe-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-1|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

HLA-DOA HLA-DPB1 CELSR1 MARF1

2.25e-041359847743a01dc9c4542e910e7c0fe046004692a680bf
ToppCellClub-club-11|World / Class top

CFB C16orf89 FCGBP

2.42e-0455983d1d832e1c98a89e2b461127922c3e4d7f42d7401
ToppCellCOVID-19-kidney-Technical/muscle_(PCT)|kidney / Disease (COVID-19 only), tissue and cell type

DNAH2 CSMD3 CSMD1 TNR

3.03e-04146984c55f1bdb6ac43b4118cb27ea7c879527e1afcbab
ToppCell356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

TRIM35 ABCA7 MTHFD2L EPB42

3.36e-04150984b6f1fc62d08199fed6156c7cd32f66d9926531b5
ToppCellTCGA-Bladder-Primary_Tumor-Urothelial_Carcinoma-Non-Papillary_Muscle_Invasive_Urothelial_Carcinoma-7|TCGA-Bladder / Sample_Type by Project: Shred V9

RASGRP4 ESPNL STAB1 CD163L1

3.36e-041509843ab17045b2c43bb4f0ebba6aa0cfb22e076a24f9
ToppCellfacs-Liver-Non-hepatocytes-3m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STAB1 SPHKAP CTRL MUC4

3.81e-041559848fdda4e3657ac56188ae88ed3caf145f4d9d1567
ToppCellfacs-Lung-EPCAM-3m-Endothelial|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NPR3 SPHKAP B3GNT2 TNR

3.81e-041559840e942609d3e060f1e589fee5997fc6299f3d18bc
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-myeloid-myeloid_dendritic-liver_dendritic_cell|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

HLA-DOA HLA-DPB1 CLCN1 FGB

3.90e-04156984411c170a7dd65269ae442b8069caf5231bddb116
ToppCellfacs-Aorta-Heart-18m-Mesenchymal-fibrocyte|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MBLAC2 ABCA7 CLCN1 CD163L1

3.90e-041569845b56217336771baf57d791efcb4e206c6aea83b1
ToppCell10x5'-Lung-Myeloid_Monocytic-Cycling_mono|Lung / Manually curated celltypes from each tissue

MAMDC4 STAB1 SPTBN5 PLK4

3.90e-0415698463b8cf14361b282872bc1c5b65d9fbc83e81a089
ToppCellfacs-Lung-EPCAM-3m-Endothelial-endothelial_cell_of_lung|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NPR3 SPHKAP B3GNT2 TNR

3.90e-04156984bb64bf520cb74897a01c64924a85a1550df2b801
ToppCelldroplet-Heart-nan-3m-Endothelial-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PAPLN ADARB1 MTHFD2L PCSK4

3.99e-04157984d85a2f56ae313baa9738e81d2756ce1fe1ba50db
ToppCellfacs-Thymus-Thymus_Flowthrough-18m-Epithelial|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRIO CD163L1 NR3C2 CTRL

4.09e-0415898412661763d1c309106801cb710c04cd2b62d16cba
ToppCelldroplet-Liver-HEPATOCYTES-1m-Epithelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFB FASN ASL FGB

4.09e-041589849f58428f70d1427b20122c5c1cc7bf521d0f4832
DrugN-succinyl-Ala-Ala-Pro-Leu-p-nitroanilide

PCSK7 CTRL PCSK4

1.49e-066973CID005044311
DrugD2-197

PCSK7 CTRL PCSK4

1.49e-066973CID000093175
DrugZ-Gly-Gly-Leu

PCSK7 CTRL PCSK4

1.21e-0511973CID000297862
Drugmercaptoacetamide

FASN PCSK7 PCSK4

1.21e-0511973CID000012961
DrugAC1NAX4S

PCSK7 PCSK4

1.80e-052972CID004459028
DrugAC1MHMZ2

PCSK7 CTRL PCSK4 PMP2

2.27e-0539974CID003007770
Diseasesensory system disease (implicated_via_orthology)

TBL1Y TBL1X

3.01e-053942DOID:0050155 (implicated_via_orthology)
Diseaseoccupational asthma (is_implicated_in)

HLA-DOA HLA-DPB1

6.00e-054942DOID:0080820 (is_implicated_in)
Diseasechronic hepatitis B virus infection

HLA-DOA HLA-DPB1 CFB

6.04e-0524943EFO_0004239
DiseaseMyasthenia Gravis

HLA-DPB1 CFB

1.49e-046942C0026896
DiseaseMyasthenia Gravis, Ocular

HLA-DPB1 CFB

1.49e-046942C0751340
DiseaseMyasthenia Gravis, Generalized

HLA-DPB1 CFB

1.49e-046942C0751339
Diseasealbuminuria

PAPLN SPHKAP NR3C2 CSMD1

2.37e-0494944EFO_0004285
Diseasemonocyte count

RASGRP4 HLA-DOA PILRA HLA-DPB1 CARMIL1 ADGRV1 CAPN10 KLHL5 GSE1 PI4KA ASL NFKBIL1 SORL1

2.81e-0413209413EFO_0005091
Diseaseresponse to clopidogrel, response to acetylsalicylate, major adverse cardiovascular event measurement

MYOM2 WDR24

3.56e-049942EFO_0020863, GO_1903492, GO_1903493
Diseasealcohol consumption measurement

SEMA3F NPIPB9 DNAH2 ANKS1B PAPLN ADGRV1 CSMD3 SPTBN5 SPHKAP NR3C2 CSMD1 SORL1

5.80e-0412429412EFO_0007878
Diseaseplasminogen activator inhibitor 1 measurement

MAP3K4 MLC1 MYOM2

6.90e-0454943EFO_0004792
Diseaseheart rate

ANKS1B CELSR1 NR3C2 CSMD1 SORL1

7.80e-04225945EFO_0004326
Diseasephosphatidylcholine 36:3 measurement

KIF2B TNR

1.03e-0315942EFO_0010381
Diseaseresponse to olanzapine

ANKS1B ADGRV1

1.03e-0315942GO_0097333
Diseasesusceptibility to hepatitis B infection measurement

HLA-DOA HLA-DPB1 CSMD1

1.13e-0364943EFO_0008405
Diseaseinterferon gamma measurement, platelet-derived growth factor BB measurement, interleukin 4 measurement, interleukin 10 measurement, stromal cell-derived factor 1 alpha measurement, interleukin-6 measurement, interleukin 12 measurement, interleukin 17 measurement, vascular endothelial growth factor measurement, fibroblast growth factor basic measurement, granulocyte colony-stimulating factor measurement

KCNV2 MEN1

1.17e-0316942EFO_0004750, EFO_0004753, EFO_0004762, EFO_0004810, EFO_0008130, EFO_0008142, EFO_0008165, EFO_0008174, EFO_0008184, EFO_0008264, EFO_0008293
Diseaseautosomal dominant intellectual developmental disorder (is_implicated_in)

TRIO AP2M1

1.32e-0317942DOID:0060307 (is_implicated_in)
Diseasefamily history of Alzheimer’s disease

PILRA ABCA7 SORL1

1.53e-0371943EFO_0009268
Diseasenucleotide measurement

CARMIL1 ANKS1B GFOD2

1.66e-0373943EFO_0010513
Diseaseurinary albumin to creatinine ratio

STAB1 KIF2B SPHKAP NR3C2

2.61e-03179944EFO_0007778
Diseasesusceptibility to plantar warts measurement

HLA-DPB1 USP6NL TBL1X

3.01e-0390943EFO_0008406
DiseaseL lactate dehydrogenase measurement

STAB1 CD163L1

3.10e-0326942EFO_0004808
Diseaseankylosing spondylitis

FASN MYOM2 CSMD1

3.11e-0391943EFO_0003898

Protein segments in the cluster

PeptideGeneStartEntry
LQWRRVSAQESQGSS

MAMDC4

511

Q6UXC1
SQRIVNGENAVLGSW

CTRL

31

P40313
VGQERWLIRSGSSQN

nan

76

P0DMU3
GEGQRGRIWIFQTST

EPB42

316

P16452
LVGWVQNTDRGTVQG

ACYP1

36

P07311
RVVAGNETQRATGWL

CEACAM18

116

A8MTB9
RSVAQAGVQWRNLGS

C16orf89

321

Q6UX73
SRRVCQADGTWSGIQ

CSMD1

3191

Q96PZ7
ISQTGGQLNSVVRWA

CSMD3

2581

Q7Z407
TVNGVWRSESRQDAG

GSE1

131

Q14687
VVRNRGNFGDVSVSW

ADGRV1

916

Q8WXG9
TAGVVSTNLIRNGDW

HLA-DPB1

166

P04440
NSGVRQAVGIQNVSW

COQ6

211

Q9Y2Z9
TVQLRGSWRVGQTAG

CAPN10

516

Q9HC96
AAWEQIQRSEGGTAQ

CELSR1

2201

Q9NYQ6
QQSHQESARDWSGGR

FLG

1096

P20930
NGTWGSVGRRNITTA

CD163L1

1161

Q9NR16
TQGVSWAAVAERVGT

DMTF1

301

Q9Y222
DAVGRVQGWALTRQQ

ABCA7

1206

Q8IZY2
WGQRQRQEVGSEAGS

TFAP2B

106

Q92481
QTWNRTFEGIAGQVS

NPR3

391

P17342
RRGQTVNAGVAERSW

MEN1

211

O00255
QVNGRWSGQTAICDN

CFB

146

P00751
STRSGSRNGDQWVMN

ANKS1B

691

Q7Z6G8
ITAGQEGQSRTTSWR

MUC4

171

Q99102
QASGVDWREGARQVS

NOL9

56

Q5SY16
QEWGVSVRTLRGNFE

ESPNL

646

Q6ZVH7
NIGAQVNTTDCWGRT

NFKBIZ

501

Q9BYH8
ERRWGQVSQAVERSS

NR3C2

16

P08235
NRRATWRAGVSSGTN

MAGED4

691

Q96JG8
GANENPGRNVSVSWR

KTI12

121

Q96EK9
NGWRTHGRNGTENIN

GPBP1

71

Q86WP2
GGTARSSVDWQIRQV

ASL

441

P04424
NGGWTVIQNRQDGSV

FGB

276

P02675
LQAEDWRTNGVGRQV

PCSK4

411

Q6UW60
INVTGVWERNVTGRG

PCSK7

166

Q16549
QTRGEQLVVSGSWDQ

PEX7

121

O00628
QTVAAVGNRRQWDGG

NEK5

646

Q6P3R8
EGSVGLSNSVSRWVQ

RASGRP4

241

Q8TDF6
GEASRRWLQQEQNST

HEXD

156

Q8WVB3
TVGSRQQATQGWINT

PI4KA

1441

P42356
SEVNIGNSQTRRSSW

EXPH5

1431

Q8NEV8
ITSQVTGQIGWRREG

AP2M1

151

Q96CW1
GSSQSWRQQEEEQRL

NFKBIL1

231

Q9UBC1
NASIQTWDGVLQGER

ADARB1

536

P78563
STVDSQQGEFWNRGQ

KLHL5

76

Q96PQ7
RVGQSEIRSISVNQW

HUWE1

911

Q7Z6Z7
EIRSISVNQWGSQLG

HUWE1

916

Q7Z6Z7
TRSSGRQQWQSIEGT

PILRA

131

Q9UKJ1
TWLRNGQTVTEGVAQ

HLA-DOA

146

P06340
RWGSTSRQGEGAVLQ

DSCR9

61

P59020
SVTQGRAAGQQRWTE

DBF4B

396

Q8NFT6
RAAGQQRWTESLDGV

DBF4B

401

Q8NFT6
ENVAWGNGRVSVTRV

FCGBP

1296

Q9Y6R7
QENVAWGNGRVSVTR

FCGBP

2496

Q9Y6R7
WGNGRVSVTRVITVQ

FCGBP

2501

Q9Y6R7
LQENVAWGNGRVSVT

FCGBP

3696

Q9Y6R7
QSFQGQGDRRTWDRT

GFOD2

316

Q3B7J2
TSQSGRRTWDGQEVV

GIMAP8

476

Q8ND71
QTGQAVSGAQVSSWR

CYP4F30P

31

Q9H0H9
RRNWAGTGHSLQQVT

C17orf98

96

A8MV24
SGNRANIWLVRGSEQ

MBLAC2

26

Q68D91
GTENSCSRTRGWLQQ

MARF1

6

Q9Y4F3
ENEWTQTRQGEGNST

DNAJC18

51

Q9H819
RTFSQEVSRRSWGQQ

CARMIL1

1321

Q5VZK9
NNSSSISGVWVFRGQ

EEF1G

366

P26641
ENWSVINSSSGERVG

CCDC168

91

Q8NDH2
RWRRQGVQVQVSTSN

FASN

1931

P49327
RVTWVSQASADQRAG

DHX37

656

Q8IY37
WSGRATRAAVATQEQ

DNAH2

21

Q9P225
TVESNRVQVRTWQGT

IFT140

496

Q96RY7
GTGSWLGRTRNQVIN

NPIPB9

26

F8W1W9
SSQWLENIQERAGGV

KIF2B

616

Q8N4N8
QRGQENTSGFWLNRS

MAP3K4

246

Q9Y6R4
SQWKREAVGNGRQAT

SPHKAP

306

Q2M3C7
VRVAAVTSRGIGNWS

SORL1

1721

Q92673
QSWRVGVVRVRQDSG

TRIM35

366

Q9UPQ4
NRGRRAQATPWTQTQ

SEMA3F

146

Q13275
AQATPWTQTQAVRGR

SEMA3F

151

Q13275
WTQTQAVRGRGSRAT

SEMA3F

156

Q13275
WSTGGQVSRASQVSN

SCYL1

666

Q96KG9
WSSQDEVSTNVRQGR

PLEKHG3

431

A1L390
WNTTENEGSQHRRSI

KCNV2

16

Q8TDN2
GNATRSGQNGNQTWR

RNF6

121

Q9Y252
SGQNGNQTWRAVSRT

RNF6

126

Q9Y252
WENGARSNVTVRNTN

RNF6

281

Q9Y252
WSRGTQEQASEQQAR

NINL

986

Q9Y2I6
QWGNQETSNSGRGRV

PLK4

346

O00444
SIQAQWTRLQGRSEQ

SPTBN5

1291

Q9NRC6
IRESWGQESNAGNQT

B3GNT2

161

Q9NY97
MEQSRSQQRGGEQSW

CLCN1

1

P35523
ARIWNLNENSNGGST

TBL1X

256

O60907
ETQGQSWTRDASRGN

USP6NL

746

Q92738
AGVSCSQRWRREGSQ

ZNF384

101

Q8TF68
VAGESVNIRWSRNGL

PAPLN

1156

O95428
GSQQWSAGTLRVERE

WDR97

886

A6NE52
WLNSVRQTGNTTRSG

RLIM

101

Q9NVW2
TTRSGQRGNQSWRAV

RLIM

111

Q9NVW2
QRGNQSWRAVSRTNP

RLIM

116

Q9NVW2
TTDGGGWIVFQRRQN

TNR

1171

Q92752
RNISGRVWVQNASVD

STAB1

1086

Q9NY15
STARIWNLNENSNGG

TBL1Y

201

Q9BQ87
EIQRGVESWVSLGNR

MTHFD2L

66

Q9H903
TRGCGTRQDAWQVTT

PLEKHG7

56

Q6ZR37
VARELGRNQVAQTWT

WDR24

436

Q96S15
QEESRTVQGGVLQGW

ZNF426

96

Q9BUY5
EGSQDRNTSWGVVQE

TLE6

221

Q9H808
QEQWLQAGNGRSTGV

TRIO

3046

O75962
VSARLQGASWDTQNG

MLC1

331

Q15049
VGSGSWQRVNAQTAV

MYOM2

551

P54296
TLQRGSLNQVQRWDG

PMP2

86

P02689