Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionfolic acid receptor activity

FOLR1 FOLR2 FOLR3

2.76e-0731313GO:0061714
GeneOntologyMolecularFunctionfolic acid binding

FOLR1 FOLR2 FOLR3 IZUMO1R

7.90e-06201314GO:0005542
GeneOntologyMolecularFunctionATP-dependent protein-DNA unloader activity

WAPL NPM2

4.27e-0521312GO:0140083
GeneOntologyMolecularFunctionvitamin binding

FOLR1 FOLR2 FOLR3 SHMT2 ETNPPL IZUMO1R AGXT2

9.40e-051611317GO:0019842
GeneOntologyMolecularFunctioncarboxylic acid binding

FOLR1 FOLR2 FOLR3 IZUMO1R UGT1A1 AKR1C3 UGT2B15 UGT2B17

1.83e-042391318GO:0031406
GeneOntologyMolecularFunctiontRNA (cytidine-3-)-methyltransferase activity

METTL2A METTL2B

2.54e-0441312GO:0052735
GeneOntologyMolecularFunctionorganic acid binding

FOLR1 FOLR2 FOLR3 IZUMO1R UGT1A1 AKR1C3 UGT2B15 UGT2B17

2.76e-042541318GO:0043177
GeneOntologyMolecularFunctionretinoic acid binding

UGT1A1 UGT2B15 UGT2B17

8.02e-04281313GO:0001972
GeneOntologyMolecularFunctionDNA-binding transcription factor activity, RNA polymerase II-specific

ZNF438 ZNF142 ZNF148 ZNF266 ZNF423 BACH1 ZNF521 BCL11A ZNF236 ZNF284 GTF2IRD2B BCL11B ZBTB39 ZNF394 NACC2 GTF2IRD2 ZNF552 ZNF561 ZNF860 PRDM15

8.83e-04141213120GO:0000981
GeneOntologyBiologicalProcessregulation of chromosome organization

WAPL ERCC4 SMC6 INO80D FBXO5 CCT5 WNT3A FEN1 SMARCA2 SMARCA4

7.37e-0626613010GO:0033044
GeneOntologyBiologicalProcessregulation of DNA metabolic process

HGF WAPL ERCC4 OTUB1 SMC6 TRRAP INO80D NPM2 FBXO5 CCT5 WNT3A SMARCA2 SMARCA4 PRKCD

1.33e-0556413014GO:0051052
GeneOntologyBiologicalProcessbiphenyl catabolic process

UGT1A1 UGT2B15 UGT2B17

1.34e-0581303GO:0070980
GeneOntologyBiologicalProcessDNA metabolic process

HGF WAPL ERCC4 ATP23 RBBP8 OTUB1 BACH1 SMC6 INTS3 TRRAP INO80D NPM2 BCL11B FBXO5 CCT5 WNT3A FEN1 SMARCA2 SMARCA4 PRKCD

1.41e-05108113020GO:0006259
GeneOntologyBiologicalProcesspositive regulation of meiotic nuclear division

WNT4 NPM2 FBXO5 EIF4G3

2.02e-05261304GO:0045836
GeneOntologyBiologicalProcessbiphenyl metabolic process

UGT1A1 UGT2B15 UGT2B17

2.84e-05101303GO:0018879
GeneOntologyBiologicalProcessfolic acid transport

FOLR1 FOLR2 FOLR3

3.89e-05111303GO:0015884
GeneOntologyBiologicalProcesscellular response to folic acid

FOLR1 FOLR2

3.94e-0521302GO:0071231
GeneOntologyBiologicalProcesspositive regulation of collateral sprouting in absence of injury

WNT3 WNT3A

3.94e-0521302GO:0048697
GeneOntologyBiologicalProcessdouble-strand break repair

ERCC4 ATP23 RBBP8 OTUB1 SMC6 INTS3 TRRAP FEN1 SMARCA2 SMARCA4

4.02e-0532413010GO:0006302
GeneOntologyBiologicalProcessxenobiotic glucuronidation

UGT1A1 UGT2B15 UGT2B17

5.16e-05121303GO:0052697
GeneOntologyBiologicalProcessfusion of sperm to egg plasma membrane involved in single fertilization

FOLR1 FOLR2 FOLR3 IZUMO1R

5.35e-05331304GO:0007342
GeneOntologyBiologicalProcesssperm-egg recognition

FOLR1 FOLR2 FOLR3 IZUMO1R CCT5

5.62e-05651305GO:0035036
GeneOntologyBiologicalProcesspositive regulation of collateral sprouting

WNT3 BCL11A WNT3A

6.68e-05131303GO:0048672
GeneOntologyBiologicalProcessplasma membrane fusion

FOLR1 FOLR2 FOLR3 IZUMO1R

8.47e-05371304GO:0045026
GeneOntologyBiologicalProcesspositive regulation of meiotic cell cycle

WNT4 NPM2 FBXO5 EIF4G3

8.47e-05371304GO:0051446
GeneOntologyBiologicalProcesspositive regulation of dermatome development

WNT4 WNT3A

1.18e-0431302GO:0061184
GeneOntologyBiologicalProcessregulation of collateral sprouting in absence of injury

WNT3 WNT3A

1.18e-0431302GO:0048696
GeneOntologyBiologicalProcesscell morphogenesis

HGF WNT3 PECAM1 SLITRK4 LRRK2 LMTK2 BCL11A WLS THOC2 ITGB6 ANKRD27 BCL11B KIDINS220 FGD4 WNT3A ARL13B SMARCA4 CFAP44 EPB41

1.76e-04119413019GO:0000902
GeneOntologyBiologicalProcessregulation of meiotic nuclear division

WNT4 NPM2 FBXO5 EIF4G3

1.84e-04451304GO:0040020
GeneOntologyBiologicalProcesssexual reproduction

ERCC4 ZNF148 ADAMTS2 RBBP8 FOLR1 FOLR2 FOLR3 WNT3 LRRK2 WNT4 IZUMO1R NPM2 FBXO5 CCT5 CCDC62 SMARCA2 EIF4G3 CFAP44 CEP57 SYCE1

2.07e-04131213020GO:0019953
GeneOntologyBiologicalProcessdermatome development

WNT4 WNT3A

2.35e-0441302GO:0061054
GeneOntologyBiologicalProcessregulation of dermatome development

WNT4 WNT3A

2.35e-0441302GO:0061183
GeneOntologyBiologicalProcesspositive regulation of DNA metabolic process

HGF TRRAP INO80D NPM2 CCT5 WNT3A SMARCA2 SMARCA4 PRKCD

2.66e-043331309GO:0051054
GeneOntologyBiologicalProcessregulation of organelle organization

HGF WAPL ERCC4 FRMD7 PECAM1 SMC6 LRRK2 WNT4 INO80D ANKRD27 NPM2 FBXO5 CCT5 WNT3A FEN1 SMARCA2 SMARCA4 PRKCD EIF4G3 PREX1

2.78e-04134213020GO:0033043
GeneOntologyBiologicalProcesscell-cell recognition

FOLR1 FOLR2 FOLR3 IZUMO1R CCT5

2.92e-04921305GO:0009988
GeneOntologyBiologicalProcesspost-translational protein targeting to endoplasmic reticulum membrane

FOLR1 FOLR2 FOLR3

2.99e-04211303GO:0006620
GeneOntologyBiologicalProcesscellular glucuronidation

UGT1A1 UGT2B15 UGT2B17

2.99e-04211303GO:0052695
GeneOntologyBiologicalProcesspositive regulation of meiosis I

FBXO5 EIF4G3

3.89e-0451302GO:0060903
GeneOntologyBiologicalProcesscollateral sprouting in absence of injury

WNT3 WNT3A

3.89e-0451302GO:0048669
GeneOntologyBiologicalProcesspositive regulation of Wnt signaling pathway

WNT3 LRRK2 WLS WNT3A SMARCA4 PRDM15

5.01e-041581306GO:0030177
GeneOntologyBiologicalProcessregulation of collateral sprouting

WNT3 BCL11A WNT3A

5.08e-04251303GO:0048670
GeneOntologyBiologicalProcesscellular process involved in reproduction in multicellular organism

FOLR1 FOLR2 FOLR3 WNT4 IZUMO1R FBXO5 CCDC62 SMARCA2 EIF4G3 CFAP44 CEP57

5.14e-0452713011GO:0022412
GeneOntologyBiologicalProcessglucuronate metabolic process

UGT1A1 UGT2B15 UGT2B17

5.72e-04261303GO:0019585
GeneOntologyBiologicalProcessuronic acid metabolic process

UGT1A1 UGT2B15 UGT2B17

5.72e-04261303GO:0006063
GeneOntologyBiologicalProcessaortic smooth muscle cell differentiation

SMARCA2 SMARCA4

5.82e-0461302GO:0035887
GeneOntologyCellularComponentSWI/SNF superfamily-type complex

BCL11A TRRAP INO80D BCL11B SMARCA2 SMARCA4

3.29e-05961326GO:0070603
GeneOntologyCellularComponentSWI/SNF complex

BCL11A BCL11B SMARCA2 SMARCA4

3.66e-05301324GO:0016514
GeneOntologyCellularComponentWnt signalosome

WNT3 LRRK2 WNT3A

1.30e-04161323GO:1990909
GeneOntologyCellularComponentATPase complex

BCL11A TRRAP INO80D BCL11B SMARCA2 SMARCA4

1.71e-041291326GO:1904949
GeneOntologyCellularComponentintegrator complex

INTS3 INTS6 INTS11

3.01e-04211323GO:0032039
DomainZnf_C2H2-like

ZNF438 ZXDC ZNF704 ZNF142 ZNF148 ZNF266 ZNF423 ZNF521 ZNF407 BCL11A ZNF236 AKAP8L ZNF284 GTF2IRD2B BCL11B ZBTB39 ZNF394 ZNF532 ZFP64 GTF2IRD2 ZNF552 ZNF561 ZNF860 PRDM15 ZNF687

1.48e-1079612825IPR015880
DomainZnF_C2H2

ZNF438 ZXDC ZNF704 ZNF142 ZNF148 ZNF266 ZNF423 ZNF521 ZNF407 BCL11A ZNF236 AKAP8L ZNF284 GTF2IRD2B BCL11B ZBTB39 ZNF394 ZNF532 ZFP64 GTF2IRD2 ZNF552 ZNF561 ZNF860 PRDM15 ZNF687

2.02e-1080812825SM00355
DomainZnf_C2H2

ZNF438 ZXDC ZNF704 ZNF142 ZNF148 ZNF266 ZNF423 ZNF521 ZNF407 BCL11A ZNF236 AKAP8L ZNF284 BCL11B ZBTB39 ZNF394 ZNF532 ZFP64 ZNF552 ZNF561 ZNF860 PRDM15 ZNF687

5.42e-0980512823IPR007087
DomainZnf_C2H2/integrase_DNA-bd

ZNF438 ZXDC ZNF142 ZNF148 ZNF266 ZNF423 ZNF521 ZNF407 BCL11A ZNF236 ZNF284 BCL11B ZBTB39 ZNF394 ZNF532 ZFP64 ZNF552 ZNF561 ZNF860 PRDM15 ZNF687

1.02e-0869412821IPR013087
DomainFolate_rcpt

FOLR1 FOLR2 FOLR3 IZUMO1R

1.05e-0851284IPR004269
DomainZINC_FINGER_C2H2_2

ZNF438 ZXDC ZNF704 ZNF142 ZNF148 ZNF266 ZNF423 ZNF521 ZNF407 BCL11A ZNF236 ZNF284 BCL11B ZBTB39 ZNF394 ZNF532 ZFP64 ZNF552 ZNF561 ZNF860 PRDM15 ZNF687

1.37e-0877512822PS50157
DomainZINC_FINGER_C2H2_1

ZNF438 ZXDC ZNF704 ZNF142 ZNF148 ZNF266 ZNF423 ZNF521 ZNF407 BCL11A ZNF236 ZNF284 BCL11B ZBTB39 ZNF394 ZNF532 ZFP64 ZNF552 ZNF561 ZNF860 PRDM15 ZNF687

1.44e-0877712822PS00028
Domain-

ZNF438 ZXDC ZNF142 ZNF148 ZNF266 ZNF423 ZNF521 ZNF407 BCL11A ZNF236 ZNF284 BCL11B ZBTB39 ZNF394 ZNF532 ZFP64 ZNF552 ZNF561 ZNF860 PRDM15

3.71e-08679128203.30.160.60
DomainFolate_rcpt-like

FOLR1 FOLR2 FOLR3 IZUMO1R

1.44e-0781284IPR018143
DomainFolate_rec

FOLR1 FOLR2 FOLR3 IZUMO1R

1.44e-0781284PF03024
Domainzf-C2H2

ZNF438 ZNF142 ZNF148 ZNF266 ZNF423 ZNF521 ZNF407 BCL11A ZNF236 ZNF284 BCL11B ZBTB39 ZNF394 ZFP64 ZNF552 ZNF561 ZNF860 PRDM15 ZNF687

2.56e-0769312819PF00096
DomainSnAC

SMARCA2 SMARCA4

4.66e-0521282SM01314
DomainWnt3

WNT3 WNT3A

4.66e-0521282IPR009141
DomainGln-Leu-Gln_QLQ

SMARCA2 SMARCA4

4.66e-0521282IPR014978
DomainSnAC

SMARCA2 SMARCA4

4.66e-0521282IPR029295
DomainSnAC

SMARCA2 SMARCA4

4.66e-0521282PF14619
DomainQLQ

SMARCA2 SMARCA4

4.66e-0521282SM00951
DomainQLQ

SMARCA2 SMARCA4

4.66e-0521282PS51666
DomainQLQ

SMARCA2 SMARCA4

4.66e-0521282PF08880
Domain-

GTF2IRD2B GTF2IRD2

2.77e-04412823.90.1460.10
DomainHSA

SMARCA2 SMARCA4

2.77e-0441282SM00573
DomainGTF2I

GTF2IRD2B GTF2IRD2

2.77e-0441282PS51139
DomainGTF2I

GTF2IRD2B GTF2IRD2

2.77e-0441282PF02946
DomainHSA

SMARCA2 SMARCA4

2.77e-0441282PS51204
DomainMeTrfase

METTL2A METTL2B

2.77e-0441282IPR026113
DomainGTF2I

GTF2IRD2B GTF2IRD2

2.77e-0441282IPR004212
DomainHSA_dom

SMARCA2 SMARCA4

2.77e-0441282IPR014012
DomainHSA

SMARCA2 SMARCA4

2.77e-0441282PF07529
DomainWnt

WNT3 WNT4 WNT3A

2.81e-04191283IPR005817
DomainWnt_CS

WNT3 WNT4 WNT3A

2.81e-04191283IPR018161
Domainwnt

WNT3 WNT4 WNT3A

2.81e-04191283PF00110
DomainWNT1

WNT3 WNT4 WNT3A

2.81e-04191283SM00097
DomainWNT1

WNT3 WNT4 WNT3A

2.81e-04191283PS00246
Domainzf-C2H2_6

ZNF266 ZNF423 ZNF521 ZNF236 ZNF284 ZNF532 ZFP64 ZNF561 ZNF860

3.17e-043141289PF13912
DomainUDPGT

UGT1A1 UGT2B15 UGT2B17

3.82e-04211283PF00201
DomainUDPGT

UGT1A1 UGT2B15 UGT2B17

3.82e-04211283PS00375
DomainUDP_glucos_trans

UGT1A1 UGT2B15 UGT2B17

3.82e-04211283IPR002213
DomainAminotrans_3

ETNPPL AGXT2

4.60e-0451282IPR005814
DomainAminotran_3

ETNPPL AGXT2

4.60e-0451282PF00202
DomainAA_TRANSFER_CLASS_3

ETNPPL AGXT2

4.60e-0451282PS00600
DomainBRK

SMARCA2 SMARCA4

6.87e-0461282SM00592
DomainMethyltransf_12

METTL2A METTL2B

6.87e-0461282PF08242
DomainMA3

EIF4G1 EIF4G3

6.87e-0461282SM00544
DomainMA3

EIF4G1 EIF4G3

6.87e-0461282PF02847
DomainBRK_domain

SMARCA2 SMARCA4

6.87e-0461282IPR006576
DomainMI

EIF4G1 EIF4G3

6.87e-0461282PS51366
DomainBRK

SMARCA2 SMARCA4

6.87e-0461282PF07533
DomainInitiation_fac_eIF4g_MI

EIF4G1 EIF4G3

6.87e-0461282IPR003891
DomainMethyltransf_12

METTL2A METTL2B

6.87e-0461282IPR013217
DomaineIF5C

EIF4G1 EIF4G3

9.57e-0471282SM00515
DomainW2

EIF4G1 EIF4G3

9.57e-0471282PF02020
DomainW2

EIF4G1 EIF4G3

9.57e-0471282PS51363
DomainW2_domain

EIF4G1 EIF4G3

9.57e-0471282IPR003307
Domainzf-C2H2_11

ZNF532 ZNF687

1.63e-0391282PF16622
Domain-

SHMT2 ETNPPL AGXT2

1.75e-033512833.90.1150.10
DomainPyrdxlP-dep_Trfase_major_sub2

SHMT2 ETNPPL AGXT2

1.90e-03361283IPR015422
DomainMIF4G

EIF4G1 EIF4G3

2.02e-03101282SM00543
DomainMIF4G

EIF4G1 EIF4G3

2.02e-03101282PF02854
DomainMIF4G-like_typ-3

EIF4G1 EIF4G3

2.02e-03101282IPR003890
DomainBTB

LZTR1 BACH1 KBTBD8 ZBTB39 NACC2

2.09e-031311285PF00651
Domain-

SHMT2 ETNPPL AGXT2

2.40e-033912833.40.640.10
DomainPyrdxlP-dep_Trfase

SHMT2 ETNPPL AGXT2

2.77e-03411283IPR015424
DomainPyrdxlP-dep_Trfase_major_sub1

SHMT2 ETNPPL AGXT2

2.77e-03411283IPR015421
DomainFERM-adjacent

FRMD7 EPB41

3.46e-03131282IPR014847
DomainFA

FRMD7 EPB41

3.46e-03131282SM01195
DomainFA

FRMD7 EPB41

3.46e-03131282PF08736
DomainFERM_M

MYO7B FRMD7 EPB41

3.85e-03461283PF00373
Domain-

MYO7B FRMD7 EPB41

4.60e-034912831.20.80.10
DomainFERM_central

MYO7B FRMD7 EPB41

4.60e-03491283IPR019748
DomainFERM_domain

MYO7B FRMD7 EPB41

4.60e-03491283IPR000299
DomainMIF4-like

EIF4G1 EIF4G3

4.62e-03151282IPR016021
Domain-

EIF4G1 EIF4G3

4.62e-031512821.25.40.180
DomainFERM_1

MYO7B FRMD7 EPB41

4.87e-03501283PS00660
DomainFERM_2

MYO7B FRMD7 EPB41

4.87e-03501283PS00661
DomainFERM_3

MYO7B FRMD7 EPB41

4.87e-03501283PS50057
DomainBand_41_domain

MYO7B FRMD7 EPB41

4.87e-03501283IPR019749
DomainB41

MYO7B FRMD7 EPB41

4.87e-03501283SM00295
DomainFERM/acyl-CoA-bd_prot_3-hlx

MYO7B FRMD7 EPB41

4.87e-03501283IPR014352
DomainBTB

LZTR1 BACH1 KBTBD8 ZBTB39 NACC2

4.92e-031601285PS50097
Domain-

TRRAP PIK3C2G

5.25e-031612821.10.1070.11
DomainPI3Kc

TRRAP PIK3C2G

5.25e-03161282SM00146
DomainPI3/4_kinase_cat_dom

TRRAP PIK3C2G

6.64e-03181282IPR000403
DomainPI3_PI4_kinase

TRRAP PIK3C2G

6.64e-03181282PF00454
DomainPI3_4_KINASE_3

TRRAP PIK3C2G

6.64e-03181282PS50290
DomainPI3_4_KINASE_1

TRRAP PIK3C2G

6.64e-03181282PS00915
DomainPI3_4_KINASE_2

TRRAP PIK3C2G

6.64e-03181282PS00916
PathwayREACTOME_WNT_LIGAND_BIOGENESIS_AND_TRAFFICKING

WNT3 WNT4 WLS WNT3A

2.02e-0525934MM14940
PathwayREACTOME_WNT_LIGAND_BIOGENESIS_AND_TRAFFICKING

WNT3 WNT4 WLS WNT3A

2.37e-0526934M27239
PathwayWP_FOLATE_METABOLISM

FOLR1 FOLR2 FOLR3 SHMT2 IZUMO1R

9.03e-0569935M39617
PathwayKEGG_MEDICUS_REFERENCE_WNT_SIGNALING_MODULATION_WNT_ACYLATION

WNT3 WNT4 WNT3A

2.49e-0419933M47836
PathwayREACTOME_METABOLISM_OF_FOLATE_AND_PTERINES

FOLR2 FOLR3 SHMT2

3.39e-0421933MM14763
PathwayREACTOME_PREDNISONE_ADME

AKR1C3 UGT2B15 UGT2B17

4.47e-0423933MM16639
PathwayKEGG_STEROID_HORMONE_BIOSYNTHESIS

UGT1A1 AKR1C3 UGT2B15 UGT2B17

4.68e-0455934M14933
PathwayREACTOME_GLUCURONIDATION

UGT1A1 UGT2B15 UGT2B17

5.09e-0424933MM14599
PathwayWP_WNT_SIGNALING_AND_PLURIPOTENCY

WNT3 LRRK2 WNT4 WNT3A PRKCD

5.39e-04101935M39387
PathwayREACTOME_GLUCURONIDATION

UGT1A1 UGT2B15 UGT2B17

5.75e-0425933M17787
PathwayWP_GLUCURONIDATION

UGT1A1 UGT2B15 UGT2B17

5.75e-0425933MM15820
PathwayKEGG_ASCORBATE_AND_ALDARATE_METABOLISM

UGT1A1 UGT2B15 UGT2B17

5.75e-0425933M605
PathwayWP_GLUCURONIDATION

UGT1A1 UGT2B15 UGT2B17

6.47e-0426933M39404
PathwayWP_WNT_SIGNALING

WNT3 WNT4 WNT3A PRKCD

6.95e-0461934MM15893
PathwayKEGG_MEDICUS_REFERENCE_WNT_SIGNALING_MODULATION_WNT_INHIBITOR

WNT3 WNT4 WNT3A

8.08e-0428933M47835
PathwayKEGG_PENTOSE_AND_GLUCURONATE_INTERCONVERSIONS

UGT1A1 UGT2B15 UGT2B17

8.08e-0428933M19580
PathwayBIOCARTA_IRES_PATHWAY

EIF4G1 EIF4G3

8.85e-047932M22028
PathwayREACTOME_ISG15_ANTIVIRAL_MECHANISM

EIF4G1 ARIH1 EIF4G3

8.97e-0429933MM17065
PathwayKEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PTCH1_TO_HEDGEHOG_SIGNALING_PATHWAY

WNT3 WNT4 WNT3A

8.97e-0429933M47372
PathwayKEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_SMO_TO_HEDGEHOG_SIGNALING_PATHWAY

WNT3 WNT4 WNT3A

8.97e-0429933M47377
Pubmed

Identification of two putative novel folate receptor genes in humans and mouse.

FOLR1 FOLR2 FOLR3 IZUMO1R

1.98e-104132411111049
Pubmed

Spatial and temporal expression of folate-related transporters and metabolic enzymes during mouse placental development.

FOLR1 FOLR2 FOLR3 IZUMO1R

1.37e-088132422365888
Pubmed

Renal tubular reabsorption of folate mediated by folate binding protein 1.

FOLR1 FOLR2 FOLR3

5.34e-083132315703271
Pubmed

Developmental consequences of in utero sodium arsenate exposure in mice with folate transport deficiencies.

FOLR1 FOLR2 FOLR3

5.34e-083132315694460
Pubmed

Mice lacking the folic acid-binding protein Folbp1 are defective in early embryonic development.

FOLR1 FOLR2 FOLR3

5.34e-083132310508523
Pubmed

Increased expression and characterization of two distinct folate binding proteins in murine erythroleukemia cells.

FOLR1 FOLR2 FOLR3

5.34e-08313238304978
Pubmed

Characterization of two cDNAs encoding folate-binding proteins from L1210 murine leukemia cells. Increased expression associated with a genomic rearrangement.

FOLR1 FOLR2 FOLR3

5.34e-08313231894617
Pubmed

Identification of amino acid residues that determine the differential ligand specificities of folate receptors alpha and beta.

FOLR1 FOLR2 FOLR3

5.34e-08313239166787
Pubmed

Selective reprogramming of regulatory T cells in solid tumors can strongly enhance or inhibit tumor growth.

FOLR2 FOLR3 IZUMO1R

5.34e-083132337928524
Pubmed

Expression patterns of folate binding proteins one and two in the developing mouse embryo.

FOLR1 FOLR2 FOLR3

5.34e-08313239973545
Pubmed

Wnt signaling controls the timing of oligodendrocyte development in the spinal cord.

WNT3 WNT4 WNT3A

2.13e-074132315950605
Pubmed

SWI/SNF chromatin-remodeling enzymes Brahma-related gene 1 (BRG1) and Brahma (BRM) are dispensable in multiple models of postnatal angiogenesis but are required for vascular integrity in infant mice.

PECAM1 SMARCA2 SMARCA4

2.13e-074132325904594
Pubmed

BRM (SNF2alpha) expression is concomitant to the onset of vasculogenesis in early mouse postimplantation development.

PECAM1 SMARCA2 SMARCA4

2.13e-074132311231080
Pubmed

Growing Mouse Oocytes Transiently Activate Folate Transport via Folate Receptors As They Approach Full Size.

FOLR1 FOLR2 FOLR3

2.13e-074132327122634
Pubmed

Mutations in folate transporter genes and risk for human myelomeningocele.

FOLR1 FOLR2 FOLR3

2.13e-074132328948692
Pubmed

Association of folate receptor (FOLR1, FOLR2, FOLR3) and reduced folate carrier (SLC19A1) genes with meningomyelocele.

FOLR1 FOLR2 FOLR3

2.13e-074132320683905
Pubmed

Gpr177 regulates pulmonary vasculature development.

WNT3 PECAM1 WNT4 WLS WNT3A

7.04e-0744132523884445
Pubmed

Folate transport in mouse cumulus-oocyte complexes and preimplantation embryos.

FOLR1 FOLR2 FOLR3

1.06e-066132323904512
Pubmed

Differential expression of human Wnt genes 2, 3, 4, and 7B in human breast cell lines and normal and disease states of human breast tissue.

WNT3 WNT4 WNT3A

1.06e-06613238168088
Pubmed

Steroidogenic enzymes and stem cell markers are upregulated during androgen deprivation in prostate cancer.

AKR1C3 UGT2B15 UGT2B17

1.06e-066132321365123
Pubmed

Wnt/beta-catenin signaling is required for CNS, but not non-CNS, angiogenesis.

WNT3 PECAM1 WNT4 WNT3A

1.13e-0621132419129494
Pubmed

Transcription factor Foxp3 and its protein partners form a complex regulatory network.

ZNF148 INTS3 INTS6 BCL11B EIF4G1 FEN1 SMARCA4 ARIH1 LAS1L EIF4G3

1.63e-063701321022922362
Pubmed

Does murine spermatogenesis require WNT signalling? A lesson from Gpr177 conditional knockout mouse models.

WNT3 WNT4 WLS WNT3A

1.66e-0623132427362799
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

WAPL ZNF423 BACH1 HECTD4 ZNF521 NBEA AKAP8L NAPB ZNF532 GLS EIF4G1 ARL13B AKR1C3 SMARCA4 NECAB3 EIF4G3 PREX1 SCAI

1.87e-0612851321835914814
Pubmed

Hetero-oligomer formation of mouse UDP-glucuronosyltransferase (UGT) 2b1 and 1a1 results in the gain of glucuronidation activity towards morphine, an activity which is absent in homo-oligomers of either UGT.

UGT1A1 UGT2B15 UGT2B17

2.95e-068132332093886
Pubmed

Simultaneous evaluation of six human glucuronidation activities in liver microsomes using liquid chromatography-tandem mass spectrometry.

UGT1A1 UGT2B15 UGT2B17

2.95e-068132322579593
Pubmed

The configuration of the 17-hydroxy group variably influences the glucuronidation of beta-estradiol and epiestradiol by human UDP-glucuronosyltransferases.

UGT1A1 UGT2B15 UGT2B17

2.95e-068132318719240
Pubmed

Associations between polymorphisms in glucuronidation and sulfation enzymes and mammographic breast density in premenopausal women in the United States.

UGT1A1 UGT2B15 UGT2B17

2.95e-068132320142249
Pubmed

A High-Density Map for Navigating the Human Polycomb Complexome.

ZXDC BCL11A INO80D ANKRD27 AKAP8L FBXO5 CCT5 EIF4G1 TIMM50 LAS1L SCAI

3.20e-064951321127705803
Pubmed

ZFP423 regulates early patterning and multiciliogenesis in the hindbrain choroid plexus.

WNT3 ZNF423 PECAM1 ARL13B

3.78e-0628132433046507
Pubmed

Ectodermal Wnt signaling regulates abdominal myogenesis during ventral body wall development.

WNT3 WNT4 WLS WNT3A

3.78e-0628132424394376
Pubmed

Oral facial clefts and gene polymorphisms in metabolism of folate/one-carbon and vitamin A: a pathway-wide association study.

FOLR1 FOLR2 FOLR3 SHMT2

4.37e-0629132419048631
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

NOL4 WAPL LZTR1 ZNF148 BCL11A TRRAP INO80D AKAP8L INTS6 BCL11B FBXO5 INTS11 TIMM50 SMARCA2 SMARCA4 ZNF687

5.48e-0611161321631753913
Pubmed

Identification of Novel Nuclear Factor of Activated T Cell (NFAT)-associated Proteins in T Cells.

ZNF148 TRRAP BCL11B TIMM50 SMARCA4 PRDM15 SCAI

5.62e-06178132727637333
Pubmed

Mouse Wnt genes exhibit discrete domains of expression in the early embryonic CNS and limb buds.

WNT3 WNT4 WNT3A

6.29e-061013238275860
Pubmed

ARID1a-DNA interactions are required for promoter occupancy by SWI/SNF.

PECAM1 SMARCA2 SMARCA4

6.29e-0610132323129809
Pubmed

The evolutionarily conserved porcupine gene family is involved in the processing of the Wnt family.

WNT3 WNT4 WNT3A

6.29e-0610132310866835
Pubmed

BAF53 forms distinct nuclear complexes and functions as a critical c-Myc-interacting nuclear cofactor for oncogenic transformation.

TRRAP SMARCA2 SMARCA4

6.29e-0610132311839798
Pubmed

NOTCH maintains developmental cardiac gene network through WNT5A.

WNT3 PECAM1 WNT4 WNT3A

6.56e-0632132430347193
Pubmed

Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.

WAPL ERCC4 HECTD4 LMTK2 TRRAP AKAP8L SMARCA2 SMARCA4 LAS1L ZNF687

7.50e-064401321034244565
Pubmed

Human transcription factor protein interaction networks.

NOL4 ERCC4 ZNF148 ZNF521 BCL11A TRRAP INO80D AKAP8L ZNF284 RNF214 CCT5 PIP4P1 EIF4G1 TIMM50 SMARCA2 SMARCA4 LAS1L ZNF687

8.11e-0614291321835140242
Pubmed

Interaction network of human early embryonic transcription factors.

NOL4 ZNF148 ZNF423 ZNF521 BCL11A AKAP8L BCL11B SMARCA2 SMARCA4

8.37e-06351132938297188
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

WAPL ZNF148 RBBP8 BACH1 INTS3 THOC2 TRRAP AKAP8L EIF4G1 SMARCA2 SMARCA4 PRKCD ZNF687

8.43e-067741321315302935
Pubmed

Nuclear-localized Asunder regulates cytoplasmic dynein localization via its role in the integrator complex.

INTS3 INTS6 INTS11

8.62e-0611132323904267
Pubmed

The chromatin-remodeling enzyme BRG1 plays an essential role in primitive erythropoiesis and vascular development.

PECAM1 SMARCA2 SMARCA4

8.62e-0611132318094026
Pubmed

WNT5A is transported via lipoprotein particles in the cerebrospinal fluid to regulate hindbrain morphogenesis.

WNT3 WNT4 WLS WNT3A

9.47e-0635132430940800
Pubmed

Foxf2 in intestinal fibroblasts reduces numbers of Lgr5(+) stem cells and adenoma formation by inhibiting Wnt signaling.

HGF WNT3 WNT4 WNT3A

9.47e-0635132423376422
Pubmed

Dual regulation of planar polarization by secreted Wnts and Vangl2 in the developing mouse cochlea.

WNT3 WNT4 WLS ARL13B

9.47e-0635132432907846
Pubmed

Role of UDP-glucuronosyltransferase isoforms in 13-cis retinoic acid metabolism in humans.

UGT1A1 UGT2B15 UGT2B17

1.15e-0512132320308471
Pubmed

Gene trap screening as an effective approach for identification of Wnt-responsive genes in the mouse embryo.

WNT3 WNT4 WNT3A

1.15e-0512132315778975
Pubmed

Gpr177/mouse Wntless is essential for Wnt-mediated craniofacial and brain development.

WNT3 WLS WNT3A

1.15e-0512132321246653
Pubmed

Epidermal Wnt controls hair follicle induction by orchestrating dynamic signaling crosstalk between the epidermis and dermis.

WNT3 WNT4 WLS WNT3A

1.32e-0538132423190887
Pubmed

The hbrm and BRG-1 proteins, components of the human SNF/SWI complex, are phosphorylated and excluded from the condensed chromosomes during mitosis.

SMARCA2 SMARCA4

1.43e-05213228670841
Pubmed

Lung cancer with loss of BRG1/BRM, shows epithelial mesenchymal transition phenotype and distinct histologic and genetic features.

SMARCA2 SMARCA4

1.43e-052132223163725
Pubmed

Combined gene dosage requirement for SWI/SNF catalytic subunits during early mammalian development.

SMARCA2 SMARCA4

1.43e-052132223076393
Pubmed

Expression of UDP Glucuronosyltransferases 2B15 and 2B17 is associated with methylation status in prostate cancer cells.

UGT2B15 UGT2B17

1.43e-052132232660355
Pubmed

COUP-TF (chicken ovalbumin upstream promoter transcription factor)-interacting protein 1 (CTIP1) is a sequence-specific DNA binding protein.

BCL11A BCL11B

1.43e-052132212196208
Pubmed

The SWI/SNF chromatin remodeling protein Brg1 is required for vertebrate neurogenesis and mediates transactivation of Ngn and NeuroD.

SMARCA2 SMARCA4

1.43e-052132215576411
Pubmed

Chromatin remodeling factors and BRM/BRG1 expression as prognostic indicators in non-small cell lung cancer.

SMARCA2 SMARCA4

1.43e-052132215240517
Pubmed

Concomitant loss of SMARCA2 and SMARCA4 expression in small cell carcinoma of the ovary, hypercalcemic type.

SMARCA2 SMARCA4

1.43e-052132226564006
Pubmed

SMARCA4/SMARCA2-deficient Carcinoma of the Esophagus and Gastroesophageal Junction.

SMARCA2 SMARCA4

1.43e-052132233027072
Pubmed

The chromatin-remodeling enzyme BRG1 promotes colon cancer progression via positive regulation of WNT3A.

WNT3A SMARCA4

1.43e-052132227852072
Pubmed

A synthetic lethality-based strategy to treat cancers harboring a genetic deficiency in the chromatin remodeling factor BRG1.

SMARCA2 SMARCA4

1.43e-052132223872584
Pubmed

Alterations of the SWI/SNF chromatin remodelling subunit-BRG1 and BRM in hepatocellular carcinoma.

SMARCA2 SMARCA4

1.43e-052132223088494
Pubmed

SWI/SNF chromatin remodeling enzyme ATPases promote cell proliferation in normal mammary epithelial cells.

SMARCA2 SMARCA4

1.43e-052132220333683
Pubmed

The UDP glucuronosyltransferase gene superfamily: suggested nomenclature based on evolutionary divergence.

UGT2B15 UGT2B17

1.43e-05213221909870
Pubmed

SWI/SNF Complex-deficient Undifferentiated Carcinoma of the Gastrointestinal Tract: Clinicopathologic Study of 30 Cases With an Emphasis on Variable Morphology, Immune Features, and the Prognostic Significance of Different SMARCA4 and SMARCA2 Subunit Deficiencies.

SMARCA2 SMARCA4

1.43e-052132234812766
Pubmed

Targeting of BRM Sensitizes BRG1-Mutant Lung Cancer Cell Lines to Radiotherapy.

SMARCA2 SMARCA4

1.43e-052132230478150
Pubmed

Androgen glucuronidation: an unexpected target for androgen deprivation therapy, with prognosis and diagnostic implications.

UGT2B15 UGT2B17

1.43e-052132224121496
Pubmed

Autism-Misregulated eIF4G Microexons Control Synaptic Translation and Higher Order Cognitive Functions.

EIF4G1 EIF4G3

1.43e-052132231999954
Pubmed

Association of periconceptional folate supplements and FOLR1 and FOLR2 gene polymorphisms with risk of congenital heart disease in offspring: A hospital-based case-control study.

FOLR1 FOLR2

1.43e-052132235545363
Pubmed

The chromatin-remodeling enzyme BRG1 modulates vascular Wnt signaling at two levels.

PECAM1 SMARCA4

1.43e-052132221262838
Pubmed

Regulation of WNT3 and WNT3A mRNAs in human cancer cell lines NT2, MCF-7, and MKN45.

WNT3 WNT3A

1.43e-052132211788904
Pubmed

Increased expression and genomic organization of a folate-binding protein homologous to the human placental isoform in L1210 murine leukemia cell lines with a defective reduced folate carrier.

FOLR2 FOLR3

1.43e-05213228307991
Pubmed

Novel associations of UDP-glucuronosyltransferase 2B gene variants with prostate cancer risk in a multiethnic study.

UGT2B15 UGT2B17

1.43e-052132224267955
Pubmed

Differential expression of the androgen-conjugating UGT2B15 and UGT2B17 enzymes in prostate tumor cells during cancer progression.

UGT2B15 UGT2B17

1.43e-052132222170718
Pubmed

The SWI/SNF ATPases Are Required for Triple Negative Breast Cancer Cell Proliferation.

SMARCA2 SMARCA4

1.43e-052132225808524
Pubmed

Effects of dietary folate intake and folate binding protein-2 (Folbp2) on urinary speciation of sodium arsenate in mice.

FOLR2 FOLR3

1.43e-052132221783456
Pubmed

eIF4 initiation factors: effectors of mRNA recruitment to ribosomes and regulators of translation.

EIF4G1 EIF4G3

1.43e-052132210872469
Pubmed

Antagonistic roles for BRM and BRG1 SWI/SNF complexes in differentiation.

SMARCA2 SMARCA4

1.43e-052132219144648
Pubmed

18F-AzaFol for Detection of Folate Receptor-β Positive Macrophages in Experimental Interstitial Lung Disease-A Proof-of-Concept Study.

FOLR2 FOLR3

1.43e-052132231824505
Pubmed

Arsenic-induced congenital malformations in genetically susceptible folate binding protein-2 knockout mice.

FOLR2 FOLR3

1.43e-052132211749123
Pubmed

CTIP1 and CTIP2 are differentially expressed during mouse embryogenesis.

BCL11A BCL11B

1.43e-052132215465497
Pubmed

High expression of SMARCA4 or SMARCA2 is frequently associated with an opposite prognosis in cancer.

SMARCA2 SMARCA4

1.43e-052132229391527
Pubmed

Expression of functional folate receptors by human parathyroid cells.

FOLR1 FOLR2

1.43e-052132224206618
Pubmed

Expression of SMARCA2 and SMARCA4 in gastric adenocarcinoma and construction of a nomogram prognostic model.

SMARCA2 SMARCA4

1.43e-052132237634210
Pubmed

Expression of two members of the Wnt family during mouse development--restricted temporal and spatial patterns in the developing neural tube.

WNT3 WNT3A

1.43e-05213222001840
Pubmed

Localization of UDP glucuronosyltransferase gene(s) on mouse chromosome 5.

UGT2B15 UGT2B17

1.43e-05213223105095
Pubmed

UDP-glucuronosyltransferase 2B15 (UGT2B15) and UGT2B17 enzymes are major determinants of the androgen response in prostate cancer LNCaP cells.

UGT2B15 UGT2B17

1.43e-052132217848572
Pubmed

Two human homologues of Saccharomyces cerevisiae SWI2/SNF2 and Drosophila brahma are transcriptional coactivators cooperating with the estrogen receptor and the retinoic acid receptor.

SMARCA2 SMARCA4

1.43e-05213228208605
Pubmed

Androgen and Estrogen Receptors in Breast Cancer Coregulate Human UDP-Glucuronosyltransferases 2B15 and 2B17.

UGT2B15 UGT2B17

1.43e-052132227496708
Pubmed

Molecular imaging of folate receptor β-positive macrophages during acute lung inflammation.

FOLR2 FOLR3

1.43e-052132225375039
Pubmed

Evi3, a common retroviral integration site in murine B-cell lymphoma, encodes an EBFAZ-related Krüppel-like zinc finger protein.

ZNF423 ZNF521

1.43e-052132212393497
Pubmed

A Brg1 null mutation in the mouse reveals functional differences among mammalian SWI/SNF complexes.

SMARCA2 SMARCA4

1.43e-052132211163203
Pubmed

Transcriptional specificity of human SWI/SNF BRG1 and BRM chromatin remodeling complexes.

SMARCA2 SMARCA4

1.43e-052132212620226
Pubmed

BRG1 and BRM SWI/SNF ATPases redundantly maintain cardiomyocyte homeostasis by regulating cardiomyocyte mitophagy and mitochondrial dynamics in vivo.

SMARCA2 SMARCA4

1.43e-052132227039070
Pubmed

Partial Inactivation of the Chromatin Remodelers SMARCA2 and SMARCA4 in Virus-Infected Cells by Caspase-Mediated Cleavage.

SMARCA2 SMARCA4

1.43e-052132229848589
Pubmed

The uridine diphosphate glucuronosyltransferase 2B15 D85Y and 2B17 deletion polymorphisms predict the glucuronidation pattern of androgens and fat mass in men.

UGT2B15 UGT2B17

1.43e-052132217698910
Pubmed

Preferred sites of glycosylphosphatidylinositol modification in folate receptors and constraints in the primary structure of the hydrophobic portion of the signal.

FOLR1 FOLR2

1.43e-05213227578066
Pubmed

Differential effects of arsenic on folate binding protein 2 (Folbp2) null and wild type fibroblasts.

FOLR2 FOLR3

1.43e-052132212368056
InteractionPORCN interactions

WNT3 WNT4 WLS WNT3A

2.75e-06161294int:PORCN
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF438 ZXDC ZNF142 ZNF148 ZNF266 ZNF423 ZNF521 ZNF407 BCL11A ZNF236 ZNF284 BCL11B ZBTB39 ZNF394 ZNF532 ZFP64 ZNF552 ZNF561 ZNF860 PRDM15

1.77e-10718882028
GeneFamilyIntegrator complex

INTS3 INTS6 INTS11

4.86e-05158831366
GeneFamilyWnt family|Endogenous ligands

WNT3 WNT4 WNT3A

1.02e-0419883360
GeneFamilyBasic leucine zipper proteins|BTB domain containing

LZTR1 BACH1 KBTBD8 ZBTB39 NACC2

4.97e-04134885861
GeneFamilyUDP glucuronosyltransferases

UGT1A1 UGT2B15 UGT2B17

4.99e-0432883363
GeneFamilyAnkyrin repeat domain containing|FERM domain containing

MYO7B FRMD7 EPB41

1.85e-03508831293
GeneFamilyParkinson disease associated genes

LRRK2 EIF4G1

2.69e-0316882672
ToppCellControl-Endothelial-Endothelial|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

EXOC6 ZNF423 PECAM1 ZNF521 KIDINS220 SMARCA2 EIF4G3

1.80e-061931327aff0649c73c634bc6ff0dc7759b4693a9236bf05
ToppCellControl-Endothelial|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

EXOC6 ZNF423 PECAM1 ZNF521 KIDINS220 SMARCA2 EIF4G3

1.80e-061931327c5f9fe03e64c211d4bcd4959e5b32f14841e336a
ToppCell356C-Fibroblasts-Fibroblast-E|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

ZNF423 KIAA0586 ZNF284 KIDINS220 PREX1 EPB41

3.27e-061361326edfd453c9a650d69d05a5a3ab15f7df56349fa86
ToppCell356C-Fibroblasts-Fibroblast-E-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

ZNF423 KIAA0586 ZNF284 KIDINS220 PREX1 EPB41

3.27e-06136132603e4e2353c23ceffde35b2d0aadd15299e3db09f
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_PRSS12|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LRRK2 ZNF521 DNAH14 PIK3C2G CPNE4 HS6ST3

1.34e-051741326ae363ce736fc8af439f3ad594d7bc2e344db80d4
ToppCelldroplet-Fat-BAT+GAT+MAT-30m-Epithelial|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NOL4 LRRC34 PPP1R36 CFAP44 CCDC158 CFAP46

1.53e-05178132658857bb8c13e0e1c6d9f5c1258f00fff62063d68
ToppCelldroplet-Fat-BAT+GAT+MAT-30m-Epithelial-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NOL4 LRRC34 PPP1R36 CFAP44 CCDC158 CFAP46

1.53e-0517813268b7df6ab8709d9ab9dff97677cc4561aec2745bc
ToppCelldroplet-Fat-BAT+GAT+MAT-30m-Epithelial-epithelial_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NOL4 LRRC34 PPP1R36 CFAP44 CCDC158 CFAP46

1.53e-051781326b0baf5667e3301898b3e45e974b8a8530af6a338
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RBBP8 ITGB6 STAC ANKRD34B FGD4 GLS

2.14e-0518913268c8ca3b30d9be6c854615459a7bfba82b427c8bc
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RBBP8 ITGB6 STAC ANKRD34B FGD4 GLS

2.14e-0518913265d902a4660a27548764bf04c6de152b565da835c
ToppCellPND10|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ZNF704 ADAMTS2 PECAM1 GLG1 SMARCA2 SMARCA4

2.21e-051901326d67e2814047c8df2ae4b7bc8be9539f5df6ecef2
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

LRRK2 BCL11A ITGB6 DNAH14 PIK3C2G FGD4

2.27e-05191132634cc997e4e5c727495f321e6807a84aa124da486
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLITRK4 BCL11A NAPB NECAB3 CPNE4 HS6ST3

2.55e-051951326ffbab350e67d9c4b66c0ab84550daec8b8139a27
ToppCellStriatum-Macroglia-CSF_related-EPENDYMAL-Ependyma_Ccdc153.Ccdc153_(Ccdc153)-|Striatum / BrainAtlas - Mouse McCarroll V32

LRRC34 MYO7B FOLR1 MKRN2OS DNAH14

2.59e-05117132526dec09112532f351fb7a2202bae84c365707b40
ToppCellStriatum-Macroglia-CSF_related-EPENDYMAL-Ependyma_Ccdc153.Ccdc153_(Ccdc153)|Striatum / BrainAtlas - Mouse McCarroll V32

LRRC34 MYO7B FOLR1 MKRN2OS DNAH14

2.59e-051171325db053c874e6739052dff1f91643e51b306236237
ToppCellStriatum-Macroglia-CSF_related-EPENDYMAL-Ependyma_Ccdc153.Ccdc153_(Ccdc153)--|Striatum / BrainAtlas - Mouse McCarroll V32

LRRC34 MYO7B FOLR1 MKRN2OS DNAH14

2.59e-05117132580780223502d18f0d86a29ff3cb74aa8235103c7
ToppCellStriatum-Macroglia-CSF_related-EPENDYMAL|Striatum / BrainAtlas - Mouse McCarroll V32

LRRC34 MYO7B FOLR1 MKRN2OS DNAH14

2.59e-05117132540889f4a387846abbf54469cc4faf616bfe348d0
ToppCellStriatum-Macroglia-CSF_related|Striatum / BrainAtlas - Mouse McCarroll V32

LRRC34 MYO7B FOLR1 MKRN2OS DNAH14

2.59e-051171325e12e37e393257db85f7f5c13454095c44f59d374
ToppCellCOVID-19-kidney-TAL|kidney / Disease (COVID-19 only), tissue and cell type

RBBP8 LRRK2 WLS ITGB6 ZNF532 FGD4

2.63e-05196132604f5eb206ed3016a737609a3ebac0c1fcabb94ef
ToppCellCOVID-19-Myeloid-Monocytes|COVID-19 / group, cell type (main and fine annotations)

ADAMTS2 PECAM1 BACH1 LRRK2 FGD4 PREX1

2.63e-05196132604d710267658ea5601ae2cfb4ed5acb8a29bd8a1
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW09-Macroglial-Glia_progenitor_cell|GW09 / Sample Type, Dataset, Time_group, and Cell type.

LRRC34 LMTK2 NACC2 ARL13B GTF2IRD2 ZNF687

2.63e-0519613267be50b9156394dea44d7b8b476d4dd516abfafae
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.0.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FOLR1 LRRK2 ITGB6 AGXT2 GLS NECAB3

2.63e-05196132665e161fd672e37a5d10f28011bb422c4d7042d6a
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L5_PT-L5_PT_VISp_C1ql2_Cdh13|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ADAMTS2 STAC BCL11B ANKRD34B CFAP44

5.33e-0513613251f3000d5f105c87c80f8ae1dd2264bcd7f757a9c
Diseasesmoking status measurement

ZNF438 NOL4 ERCC4 ATP23 WNT3 ZNF423 HECTD4 LMTK2 ZNF521 ZNF407 INO80D BCL11B ZNF394 CPNE4 EIF4G3 HS6ST3 SCAI

1.15e-05116012817EFO_0006527
DiseaseDNA repair protein RAD51 homolog 4 measurement

ZNF394 UGT2B15 UGT2B17

1.28e-05111283EFO_0801531
Disease5alpha-androstan-3beta,17beta-diol monosulfate (2) measurement

ZNF394 UGT2B15 UGT2B17

1.70e-05121283EFO_0800291
Diseaseandrostenediol (3alpha, 17alpha) monosulfate (3) measurement

ZNF394 UGT2B15 UGT2B17

2.21e-05131283EFO_0800293
Disease5alpha-androstan-3alpha,17alpha-diol monosulfate measurement

ZNF394 UGT2B15 UGT2B17

2.80e-05141283EFO_0800283
Diseasecholic acid glucuronide measurement

UGT2B15 UGT2B17

5.59e-0531282EFO_0800574
Disease5alpha-androstan-3alpha,17beta-diol monosulfate (1) measurement

ZNF394 UGT2B15 UGT2B17

6.20e-05181283EFO_0800288
Diseaseetiocholanolone glucuronide measurement

ZNF394 UGT2B15 UGT2B17

7.34e-05191283EFO_0800362
DiseaseX-25937 measurement

UGT2B15 UGT2B17

1.11e-0441282EFO_0800937
DiseaseX-24947 measurement

ZNF394 UGT2B15 UGT2B17

1.16e-04221283EFO_0800910
Diseaseepiandrosterone sulfate measurement

ZNF394 UGT2B15 UGT2B17

1.71e-04251283EFO_0021120
DiseaseMENTAL RETARDATION, AUTOSOMAL DOMINANT 12

SMARCA2 SMARCA4

1.85e-0451282C3281201
Diseasecortolone glucuronide (1) measurement

AKR1C3 UGT2B15

2.77e-0461282EFO_0800552
Diseasebilirubin metabolic disorder (is_implicated_in)

HGF UGT1A1

2.77e-0461282DOID:2741 (is_implicated_in)
Diseasecotinine measurement, trans-3-hydroxycotinine measurement

SMARCA2 UGT2B15

2.77e-0461282EFO_0007813, EFO_0010707
DiseaseX-24574 measurement

UGT2B15 UGT2B17

3.87e-0471282EFO_0800897
Diseaseandrosterone sulfate measurement

ZNF394 UGT2B15 UGT2B17

3.96e-04331283EFO_0021117
Diseasecognitive function measurement

ZNF438 ERCC4 ATP23 WNT3 PSD3 ZNF521 NBEA BCL11A WNT4 STAC RNF214 BCL11B FGD4 UGT2B15 CEP57 PREX1

4.90e-04143412816EFO_0008354
Diseasedeoxycholic acid glucuronide measurement

UGT2B15 UGT2B17

5.14e-0481282EFO_0800575
Diseaseopportunistic bacterial infectious disease (implicated_via_orthology)

SMARCA2 SMARCA4

6.59e-0491282DOID:0050340 (implicated_via_orthology)
DiseaseCarcinoma, Small Cell

UGT1A1 SMARCA4

6.59e-0491282C0262584
Diseaseobsolete_red blood cell distribution width

BACH1 KBTBD8 HECTD4 MKRN2OS ZNF407 BCL11A ANKRD27 GTF2IRD2B CCT5 GTF2IRD2 SMARCA2 UGT2B15 EIF4G3 PPP1R36 CEP57

7.56e-04134712815EFO_0005192
DiseaseIntellectual Disability

ZNF142 FOLR1 NBEA BCL11A TRRAP BCL11B ARL13B LAS1L

7.65e-044471288C3714756
Diseasemetabolite measurement

PSD3 SHMT2 UGT1A1 AGXT2 ZNF394 AKR1C3 UGT2B15 UGT2B17 METTL2B

7.75e-045601289EFO_0004725
Disease4-androsten-3alpha,17alpha-diol monosulfate (3) measurement

UGT2B15 UGT2B17

8.21e-04101282EFO_0022090
Diseaseserum metabolite measurement

ERCC4 FOLR1 FOLR2 WNT3 PSD3 STAC UGT1A1 AGXT2 BCL11B AKR1C3 UGT2B15 PRKCD

8.60e-0494512812EFO_0005653
Diseasecancer (implicated_via_orthology)

ERCC4 ITGB6 FEN1 TIMM50 SMARCA2 SMARCA4

1.14e-032681286DOID:162 (implicated_via_orthology)
Disease3-aminoisobutyrate measurement

AGXT2 PRKCD

1.20e-03121282EFO_0010980
DiseaseMalignant mesothelioma

HGF ADAMTS2 WNT3 SMARCA2

1.32e-031091284C0345967
DiseaseCoffin-Siris syndrome

SMARCA2 SMARCA4

1.41e-03131282C0265338
DiseaseX-19141 measurement

UGT2B15 UGT2B17

1.41e-03131282EFO_0800799
Diseaseparental longevity

ZNF704 HECTD4 PSD3 BCL11A ANKRD27 SMARCA2 SMARCA4 HS6ST3

1.45e-034941288EFO_0007796
Diseasesuperior frontal gyrus grey matter volume measurement

SMARCA2 EIF4G3

1.64e-03141282EFO_0006516
Diseasealcohol use disorder (implicated_via_orthology)

PSD3 SHMT2 FADS2B SMARCA2 SMARCA4

1.64e-031951285DOID:1574 (implicated_via_orthology)
Diseaseurate measurement

NOL4 FOLR1 FOLR2 HECTD4 PSD3 LMTK2 SHMT2 ITGB6 PRKCD HERC6 HS6ST3

1.83e-0389512811EFO_0004531
Diseasemetabolic syndrome

EXOC6 HECTD4 PSD3 SMARCA4 CPNE4

1.84e-032001285EFO_0000195
Diseasepreeclampsia, parental genotype effect measurement

WLS WNT3A

2.15e-03161282EFO_0000668, EFO_0005939
Diseaseattention deficit hyperactivity disorder, substance abuse, antisocial behaviour measurement

ERCC4 WNT3 ZNF423 ZNF407 NBEA BCL11A RASL11A CPNE4 HS6ST3 SCAI

2.63e-0380112810EFO_0003888, EFO_0007052, MONDO_0002491
DiseaseSeizures

ZNF142 FOLR1 NBEA TRRAP PRKCD

2.67e-032181285C0036572
Diseasecystathionine measurement

PSD3 AKR1C3

3.04e-03191282EFO_0010474
Diseasegestational age

FRMD7 WNT4 WNT3A ZNF561

3.12e-031381284EFO_0005112
Diseasesporadic amyotrophic lateral sclerosis

LRRC8C WAPL ETNPPL EPB41

3.29e-031401284EFO_0001357
Diseaseandrosterone glucuronide measurement

UGT2B15 UGT2B17

3.37e-03201282EFO_0800317
DiseaseJoubert syndrome 1

KIAA0586 ARL13B

3.71e-03211282C4551568
Diseaserenal system measurement, blood urea nitrogen measurement

KBTBD8 HECTD4

4.07e-03221282EFO_0004741, EFO_0004742

Protein segments in the cluster

PeptideGeneStartEntry
EVNQIHEDCKHMGLL

AGXT2

456

Q9BYV1
KHRNMHCKVSLLDDT

EPB41

206

P11171
KMHKLTPEQLDCIHD

BACH1

546

O14867
HTKLEHSVCANEMRK

RBBP8

191

Q99708
HIADCSGKFKMLEHA

CCDC62

176

Q6P9F0
MDSKHQCVKLNDGHF

AKR1C3

1

P42330
LHLMKQHSKALCNDR

CEP57

311

Q86XR8
LDHLVKALQKMCLHE

CFAP46

1461

Q8IYW2
KLCKDAGMNVDIHPH

C16orf78

231

Q8WTQ4
EKDSDGCHLKHKMEH

ARL13B

281

Q3SXY8
GCHLKHKMEHEQIET

ARL13B

286

Q3SXY8
VHGNHVKCVKMLLES

ANKRA2

256

Q9H9E1
VHGNKRHMNKCILSL

CFAP44

1206

Q96MT7
HCHPGVVKAALKQME

ETNPPL

61

Q8TBG4
DHKMVHRGFCAALSK

ADAMTS2

886

O95450
AMEHFVKKVEAAHCA

AKAP8L

471

Q9ULX6
CMKHDELLAEHIKSL

INTS3

881

Q68E01
GKKLMHCRSHEEVNT

INTS6

796

Q9UL03
DHCLGSHKMFQKDKS

PIK3C2G

346

O75747
CDEVKAHLLADMAHI

SHMT2

241

P34897
DKMGNSVKGIHFCHD

GLS

506

O94925
KCHVTIEKDGGCNHM

ARIH1

346

Q9Y4X5
PLMIACKTKHVDHQS

ANKRD34B

46

A5PLL1
DHDKDTVQKMCHPLC

ANKRD27

421

Q96NW4
DAMKHSGCAVNKDRH

ATP23

71

Q9Y6H3
GHLECVKHLLAMGAD

KIDINS220

181

Q9ULH0
LHLPDSHLNKTCMKN

LETM2

36

Q2VYF4
HCLVALHMCKHDIKN

LRRC34

266

Q8IZ02
LHMCKHDIKNSGIQQ

LRRC34

271

Q8IZ02
DKTQALDMKRHCLHI

LZTR1

781

Q8N653
FLQKNKAGGMHHICI

MCEE

111

Q96PE7
IKDCMKKVVAVHLHQ

INTS11

126

Q5TA45
DELLNICMNAKHHKR

IZUMO1R

21

A6ND01
MNVHHKCREKVANLC

PRKCD

266

Q05655
QDCLEGKIMHFHQKH

FRMD7

151

Q6ZUT3
DHACTQASKLKRHMK

BCL11A

411

Q9H165
EHAMLAKTAGVKHLI

GSPT2

331

Q8IYD1
QHQKKCSHMKVGDTA

ITGB6

401

P18564
CHSHAKMLSEVLRVK

PECAM1

481

P16284
QKQKICGSLTLQHHM

FGD4

331

Q96M96
HCNVKALLGMMKELH

HERC6

556

Q8IVU3
IMEEQHKCSSKSLEH

METTL2B

136

Q6P1Q9
KHIHSPEVAESGCKM

LRRK2

451

Q5S007
HELTHKKMPHINDCR

LAS1L

156

Q9Y4W2
ACEVAAGLAAMHKLH

LMTK2

246

Q8IWU2
TDLLNVCMNAKHHKT

FOLR3

31

P41439
IMGNEKCSQHHRGKV

HGF

636

P14210
IEAHHLSSICDIMEK

HECTD4

261

Q9Y4D8
RNHDKEIEKMCNFHH

EXOC6

56

Q8TAG9
AIMEKKDCPRNHSHT

HS6ST3

221

Q8IZP7
KELERQKHMCSVLQH

LRRFIP2

426

Q9Y608
EMIICFDAAHKHSGK

KBTBD8

286

Q8NFY9
IMEEQHKCSSKSLEH

METTL2A

136

Q96IZ6
NHVVHKFVMCHLKGL

FADS2B

231

A8MWK0
MCKESDHIHIIALAQ

OTUB1

211

Q96FW1
HQKDMNEKCAIGVTH

GLG1

726

Q92896
QHNDECKHLLSLMGI

FEN1

136

P39748
DHACSQASKLKRHMK

BCL11B

461

Q9C0K0
LSDDHSKILVHCVMG

DUSP29

136

Q68J44
KMKCDFNCNHVHSGL

FBXO5

46

Q9UKT4
GTVILNLCKIHKMHS

CPNE4

281

Q96A23
GETQMHLLECAHDLK

GUCY2F

256

P51841
HLLECAHDLKMTDGT

GUCY2F

261

P51841
DLLNVCMDAKHHKTK

FOLR2

26

P14207
REKLEKVHAGLMCHL

DNAH14

1036

Q0VDD8
KVHAGLMCHLEEVAD

DNAH14

1041

Q0VDD8
MHDCVVKLLKNHDEE

EIF4G1

916

Q04637
THQTPLCEEHAKKMD

INO80D

501

Q53TQ3
GKKICEHDSMSTLHF

CCDC158

201

Q5M9N0
HPESLCAQKLKMDHV

GTF2IRD2

656

Q86UP8
HPESLCAQKLKMDHV

GTF2IRD2B

656

Q6EKJ0
LSEILHLLCKQMSHK

EIF4G3

1356

O43432
LHTICLGEKAKEEMH

NPM2

46

Q86SE8
KMHQHVVKCGVCNEA

PIP4P1

96

Q86T03
TELLNVCMNAKHHKE

FOLR1

31

P15328
HLCKEVSKMHGLSGE

RASL11A

191

Q6T310
KHITSLKEAVDMTCH

GTF2H2C;

126

Q6P1K8
CGSMQLQLRKHDHKT

SLITRK4

661

Q8IW52
GEMTVLGHVKHKLVC

POLR3D

371

P05423
HDKGIVEDIHCGSMK

SMARCA2

81

P51531
DEGHRMKNHHCKLTQ

SMARCA2

851

P51531
ECGKGMKTKHALRHH

PRDM15

1116

P57071
EEEKMCDHLISAAKH

NBEA

2016

Q8NFP9
LCNNGFMHHVLEKSE

PREX1

571

Q8TCU6
DEGHRMKNHHCKLTQ

SMARCA4

881

P51532
IDCLHKGTNDMKQQH

CCT5

491

P48643
CQKRMHLNPDGTDHK

NOL4

161

O94818
DEGMTLLCEALKHSH

NLRP9

756

Q7RTR0
KGSHPMCKEHEDEKI

TRIM63

116

Q969Q1
HDISHCLKAQMEKIG

TMEM31

106

Q5JXX7
HPMACTHVLHKECIK

RNF214

671

Q8ND24
SLDNHMGIHTDEKLC

ZNF561

211

Q8N587
RGHKEKGVVMQCSHL

ZNF532

666

Q9HCE3
KSFCMLLHLGQHKII

ZNF738

211

Q8NE65
MDGHHVKDISCLNRD

TIMM50

226

Q3ZCQ8
EEHGNKCKQSFHMVT

ZNF394

311

Q53GI3
KAHMKGHEQESLFKC

ZXDC

256

Q2QGD7
VHLLPADNCIMDEHK

THOC2

286

Q8NI27
MHCAEAGKALIKFNH

MKRN2OS

1

H3BPM6
HNCHMGITAENVAKK

ACAT2

156

Q9BWD1
CQEKESEAHRKHTML

SYCE1

116

Q8N0S2
SEAHRKHTMLQECKE

SYCE1

121

Q8N0S2
NKKSLKCEQHMGHRA

TRBV4-1

36

A0A577
KTMHLDKPEQAHICQ

ZNF521

426

Q96K83
NHMIDEGLNHECKLC

ZNF521

1216

Q96K83
HMIVGTNAKHGLRCK

STAC

126

Q99469
AMLLSGCSHLLHNKE

UGT1A1

121

P22309
GCSHLLHNKELMASL

UGT1A1

126

P22309
TTILDHMHLKCKCHG

WNT3

196

P56703
NKALQHAGKHMEDCI

WAPL

1106

Q7Z5K2
DAIHKRNQSHKEMHC

SCAI

401

Q8N9R8
GIIESIHLKNFMCHS

SMC6

46

Q96SB8
KHHMCCGKEKISDTQ

PPP1R36

216

Q96LQ0
CQAAKLHMQLQSKHD

NAPB

66

Q9H115
STIKCHLKTHSGALM

ZBTB39

646

O15060
KRDCGKKMSHQHVFS

ZNF704

11

Q6ZNC4
GCMKHFSTKDILSQH

ZNF552

216

Q9H707
GRQAIASHMHLKCKC

WNT3A

191

P56704
QTHMIKHTGEKPHAC

ZNF236

241

Q9UL36
HAREHKDKGLVMQCS

ZNF687

581

Q8N1G0
KAILTHMRVECKCHG

WNT4

196

P56705
RIHMGEKHHKCDDCG

ZNF860

586

A6NHJ4
KNCRSLMHHVKNIAE

ERCC4

861

Q92889
AKLLCHLIEHSFEGM

ZNF423

1211

Q2M1K9
MCHENHDKKLNRCAI

ZNF148

276

Q9UQR1
VGKMHAHEKIHQCPE

ZNF142

391

P52746
SSHKLRHQGKSLMCE

ZNF142

501

P52746
ILHTGKHEGVKMYNC

ZNF407

1761

Q9C0G0
HDNIAHMKAKGAALS

UGT2B15

401

P54855
MSVKCVDARKNHHKT

WLS

46

Q5T9L3
LHHGENRLKKLMCCE

ZNF438

556

Q7Z4V0
LHGHVNIGKKMTCQE

PSD3

691

Q9NYI0
GLHKQHMKDLFVELC

TRRAP

796

Q9Y4A5
CHFKTVHGMKDLDRH

ZFP64

306

Q9NTW7
HDNIAHMKAKGAALS

UGT2B17

401

O75795
EKLHCHDHEKQMNVF

KIAA0586

221

Q9BVV6
QDLCKHQMDHTGDKP

ZNF284

356

Q2VY69
SCLSQHMKIHVGEKP

ZNF266

281

Q14584
HLQKMCIHNDGTKLV

LRRC8C

566

Q8TDW0
LMNCHLCAGVKHKVL

NACC2

361

Q96BF6
EMCMHIAHKQGLSDH

MYO7B

1221

Q6PIF6
QSHCLHVSAQKMLDG

NECAB3

326

Q96P71