Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	structural constituent of nuclear pore	POM121 NPAP1 POM121L2 POM121C POM121B	3.50e-08	25	76	5	GO:0017056
GeneOntologyMolecularFunction	nuclear localization sequence binding	POM121 NPAP1 POM121L2 POM121C POM121B	5.28e-08	27	76	5	GO:0008139
GeneOntologyMolecularFunction	signal sequence binding	POM121 NPAP1 POM121L2 POM121C POM121B	1.43e-06	51	76	5	GO:0005048
GeneOntologyMolecularFunction	histone H3K4 monomethyltransferase activity	KMT2D KMT2A	3.94e-04	8	76	2	GO:0140945
GeneOntologyMolecularFunction	histone H3K4 trimethyltransferase activity	KMT2D KMT2A	6.31e-04	10	76	2	GO:0140999
GeneOntologyMolecularFunction	nucleoside-triphosphatase regulator activity	TBC1D5 DENND4B ARHGAP44 SERGEF PLEKHG2 ARHGEF17 DENND1A PLXNB1	6.79e-04	507	76	8	GO:0060589
GeneOntologyMolecularFunction	GTPase regulator activity	TBC1D5 DENND4B ARHGAP44 SERGEF PLEKHG2 ARHGEF17 DENND1A PLXNB1	6.79e-04	507	76	8	GO:0030695
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	TBX22 HIVEP3 NFATC1 PER1 ETV1 E2F7 POU2F2 GATA5 ZNF581 BCL6 FOXH1 ATF6B NOTCH2	9.45e-04	1271	76	13	GO:0000987
GeneOntologyMolecularFunction	transcription corepressor binding	PER3 PER1 BCL6	1.48e-03	59	76	3	GO:0001222
GeneOntologyBiologicalProcess	mature B cell differentiation	NFATC1 POU2F2 BCL6 NOTCH2	2.83e-05	47	77	4	GO:0002335
GeneOntologyBiologicalProcess	RNA export from nucleus	POM121 NPAP1 POM121L2 POM121C POM121B	2.98e-05	96	77	5	GO:0006405
GeneOntologyBiologicalProcess	regulation of small GTPase mediated signal transduction	DENND4B ARHGAP44 BCL6 ARHGEF17 DENND1A AGRN PLXNB1 NOTCH2	3.39e-05	333	77	8	GO:0051056
GeneOntologyBiologicalProcess	nuclear pore organization	POM121 POM121C POM121B	3.92e-05	18	77	3	GO:0006999
GeneOntologyBiologicalProcess	protein import into nucleus	POM121 NPAP1 POM121L2 POM121C POM121B FAM53C	8.98e-05	195	77	6	GO:0006606
GeneOntologyBiologicalProcess	import into nucleus	POM121 NPAP1 POM121L2 POM121C POM121B FAM53C	1.06e-04	201	77	6	GO:0051170
GeneOntologyBiologicalProcess	regulation of Rab protein signal transduction	DENND4B DENND1A	2.04e-04	6	77	2	GO:0032483
GeneOntologyBiologicalProcess	regulation of hair cycle	NFATC1 FA2H PER1	2.30e-04	32	77	3	GO:0042634
GeneOntologyBiologicalProcess	regulation of GTPase activity	EPHA2 TBC1D5 ARHGAP44 BCL6 DENND1A AGRN PLXNB1	2.54e-04	335	77	7	GO:0043087
GeneOntologyCellularComponent	nuclear pore	POM121 NPAP1 POM121L2 POM121C POM121B	3.35e-05	101	76	5	GO:0005643
Domain	Period_circadian-like_C	PER3 PER1	4.26e-05	3	71	2	IPR022728
Domain	Period_C	PER3 PER1	4.26e-05	3	71	2	PF12114
Domain	FYrich_C	KMT2D KMT2A	1.41e-04	5	71	2	IPR003889
Domain	FYrich_N	KMT2D KMT2A	1.41e-04	5	71	2	IPR003888
Domain	FYRC	KMT2D KMT2A	1.41e-04	5	71	2	SM00542
Domain	FYRN	KMT2D KMT2A	1.41e-04	5	71	2	SM00541
Domain	FYRN	KMT2D KMT2A	1.41e-04	5	71	2	PF05964
Domain	FYRC	KMT2D KMT2A	1.41e-04	5	71	2	PF05965
Domain	FYRC	KMT2D KMT2A	1.41e-04	5	71	2	PS51543
Domain	FYRN	KMT2D KMT2A	1.41e-04	5	71	2	PS51542
Domain	YD	NID2 TENM2	1.41e-04	5	71	2	IPR006530
Domain	EGF_CA	NID2 AGRN TENM2 NOTCH2	1.20e-03	122	71	4	SM00179
Domain	RECEPTOR_TYR_KIN_V_2	EPHA6 EPHA2	1.26e-03	14	71	2	PS00791
Domain	RECEPTOR_TYR_KIN_V_1	EPHA6 EPHA2	1.26e-03	14	71	2	PS00790
Domain	Eph_TM	EPHA6 EPHA2	1.26e-03	14	71	2	IPR027936
Domain	PLAC	ADAMTS10 ADAMTSL3	1.26e-03	14	71	2	PF08686
Domain	Tyr_kinase_rcpt_V_CS	EPHA6 EPHA2	1.26e-03	14	71	2	IPR001426
Domain	EPH_lbd	EPHA6 EPHA2	1.26e-03	14	71	2	SM00615
Domain	Ephrin_lbd	EPHA6 EPHA2	1.26e-03	14	71	2	PF01404
Domain	uDENN	DENND4B DENND1A	1.26e-03	14	71	2	SM00800
Domain	EphA2_TM	EPHA6 EPHA2	1.26e-03	14	71	2	PF14575
Domain	Tyr_kinase_ephrin_rcpt	EPHA6 EPHA2	1.26e-03	14	71	2	IPR016257
Domain	Ephrin_rcpt_lig-bd_dom	EPHA6 EPHA2	1.26e-03	14	71	2	IPR001090
Domain	EPH_LBD	EPHA6 EPHA2	1.26e-03	14	71	2	PS51550
Domain	EGF-like_Ca-bd_dom	NID2 AGRN TENM2 NOTCH2	1.28e-03	124	71	4	IPR001881
Domain	uDENN	DENND4B DENND1A	1.45e-03	15	71	2	PF03456
Domain	UDENN	DENND4B DENND1A	1.65e-03	16	71	2	PS50946
Domain	DDENN	DENND4B DENND1A	1.65e-03	16	71	2	PS50947
Domain	Post-SET_dom	KMT2D KMT2A	1.65e-03	16	71	2	IPR003616
Domain	DENN	DENND4B DENND1A	1.65e-03	16	71	2	SM00799
Domain	PostSET	KMT2D KMT2A	1.65e-03	16	71	2	SM00508
Domain	dDENN	DENND4B DENND1A	1.65e-03	16	71	2	SM00801
Domain	DENN	DENND4B DENND1A	1.65e-03	16	71	2	PF02141
Domain	dDENN_dom	DENND4B DENND1A	1.65e-03	16	71	2	IPR005112
Domain	uDENN_dom	DENND4B DENND1A	1.65e-03	16	71	2	IPR005113
Domain	dDENN	DENND4B DENND1A	1.65e-03	16	71	2	PF03455
Domain	DENN	DENND4B DENND1A	1.65e-03	16	71	2	PS50211
Domain	DENN_dom	DENND4B DENND1A	1.65e-03	16	71	2	IPR001194
Domain	AT_hook	BAZ2A KMT2A	1.65e-03	16	71	2	PF02178
Domain	POST_SET	KMT2D KMT2A	1.65e-03	16	71	2	PS50868
Domain	PLAC	ADAMTS10 ADAMTSL3	2.34e-03	19	71	2	PS50900
Domain	PLAC	ADAMTS10 ADAMTSL3	2.34e-03	19	71	2	IPR010909
Domain	PHD	KMT2D BAZ2A KMT2A	2.92e-03	75	71	3	PF00628
Domain	Growth_fac_rcpt_	NID2 EPHA6 EPHA2 NOTCH2	2.95e-03	156	71	4	IPR009030
Domain	EPHD	KMT2D KMT2A	3.13e-03	22	71	2	PS51805
Domain	Quino_amine_DH_bsu	NID2 TENM2	3.13e-03	22	71	2	IPR011044
Domain	EGF-like_CS	NID2 EPHA2 AGRN TENM2 NOTCH2	3.15e-03	261	71	5	IPR013032
Domain	EGF_2	NID2 EPHA2 AGRN TENM2 NOTCH2	3.36e-03	265	71	5	PS01186
Domain	Znf_PHD-finger	KMT2D BAZ2A KMT2A	3.39e-03	79	71	3	IPR019787
Domain	PAS_fold_3	PER3 PER1	3.42e-03	23	71	2	IPR013655
Domain	PAS_3	PER3 PER1	3.42e-03	23	71	2	PF08447
Domain	PAS-assoc_C	PER3 PER1	3.73e-03	24	71	2	IPR000700
Domain	Peptidase_M12B_ADAM-TS	ADAMTS10 ADAMTSL3	3.73e-03	24	71	2	IPR013273
Domain	Ephrin_rec_like	EPHA6 EPHA2	4.04e-03	25	71	2	SM01411
Domain	Tyr-kin_ephrin_A/B_rcpt-like	EPHA6 EPHA2	4.04e-03	25	71	2	IPR011641
Domain	PAC	PER3 PER1	4.37e-03	26	71	2	IPR001610
Domain	PAC	PER3 PER1	4.37e-03	26	71	2	SM00086
Domain	PAC	PER3 PER1	4.37e-03	26	71	2	PS50113
Domain	TyrKc	EPHA6 EPHA2 MAP3K11	4.59e-03	88	71	3	SM00219
Domain	Tyr_kinase_cat_dom	EPHA6 EPHA2 MAP3K11	4.59e-03	88	71	3	IPR020635
Domain	IPT	NFATC1 PLXNB1	4.70e-03	27	71	2	SM00429
Domain	AT_hook	BAZ2A KMT2A	4.70e-03	27	71	2	SM00384
Domain	AT_hook_DNA-bd_motif	BAZ2A KMT2A	4.70e-03	27	71	2	IPR017956
Domain	PHD	KMT2D BAZ2A KMT2A	4.73e-03	89	71	3	SM00249
Domain	Znf_PHD	KMT2D BAZ2A KMT2A	5.04e-03	91	71	3	IPR001965
Domain	ZF_PHD_2	KMT2D BAZ2A KMT2A	5.68e-03	95	71	3	PS50016
Domain	ZF_PHD_1	KMT2D BAZ2A KMT2A	5.84e-03	96	71	3	PS01359
Domain	TIG	NFATC1 PLXNB1	6.17e-03	31	71	2	PF01833
Domain	IPT	NFATC1 PLXNB1	6.57e-03	32	71	2	IPR002909
Domain	PAS	PER3 PER1	6.57e-03	32	71	2	SM00091
Domain	PAS	PER3 PER1	7.39e-03	34	71	2	IPR000014
Pathway	REACTOME_POSTMITOTIC_NUCLEAR_PORE_COMPLEX_NPC_REFORMATION	POM121 POM121C POM121B	1.13e-04	24	56	3	MM15658
Pathway	REACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS	ADAMTS10 MUC5B ADAMTSL3 NOTCH2	1.51e-04	68	56	4	M27303
Pathway	REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY	MAMLD1 HDAC10 NOTCH2	1.81e-04	28	56	3	M6177
Pathway	REACTOME_DISEASES_OF_GLYCOSYLATION	ADAMTS10 MUC5B ADAMTSL3 AGRN NOTCH2	2.52e-04	143	56	5	M27275
Pubmed	POM121 inhibits the macrophage inflammatory response by impacting NF-κB P65 nuclear accumulation.	POM121 POM121C POM121B	1.04e-08	3	77	3	30802453
Pubmed	Nucleoporin POM121 signals TFEB-mediated autophagy via activation of SIGMAR1/sigma-1 receptor chaperone by pridopidine.	POM121 POM121C POM121B	1.04e-08	3	77	3	35507432
Pubmed	A census of human transcription factors: function, expression and evolution.	TBX22 HIVEP3 KMT2D NFATC1 ETV1 E2F7 KMT2A POU2F2 GATA5 BCL6 FOXH1 ATF6B MBNL3 ZNF541	1.13e-08	908	77	14	19274049
Pubmed	Two distinct human POM121 genes: requirement for the formation of nuclear pore complexes.	POM121 POM121C POM121B	4.17e-08	4	77	3	17900573
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	HIVEP3 POM121 PER3 WDR11 KIAA0586 PER1 N4BP1 POM121C POM121B SH2B1	1.40e-07	493	77	10	15368895
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	HIVEP3 DAZAP1 EPHA6 NFATC1 WDR11 TBC1D5 ARHGAP44 ETV1 KATNIP ANKRD12 DENND1A SH3RF3 SH2B1 WNK2 NOTCH2	8.03e-07	1489	77	15	28611215
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	HIVEP3 KMT2D NFATC1 ARHGAP44 PER1 MAP3K11 ZC3H7B POM121C DENND1A AGRN WNK2 NOTCH2 RBM38	8.75e-07	1105	77	13	35748872
Pubmed	Limited expression of nuclear pore membrane glycoprotein 210 in cell lines and tissues suggests cell-type specific nuclear pores in metazoans.	POM121 POM121C POM121B	4.66e-06	15	77	3	14697343
Pubmed	PERIOD1 (PER1) has anti-apoptotic effects, and PER3 has pro-apoptotic effects during cisplatin (CDDP) treatment in human gingival cancer CA9-22 cells.	PER3 PER1	4.84e-06	2	77	2	21459569
Pubmed	The structure of the human betaII-tryptase tetramer: fo(u)r better or worse.	TPSAB1 TPSB2	4.84e-06	2	77	2	10500112
Pubmed	Characterization of a tryptase mRNA expressed in the human basophil cell line KU812.	TPSAB1 TPSB2	4.84e-06	2	77	2	8434231
Pubmed	Potential clinical utility of MUC5B und TOLLIP single nucleotide polymorphisms (SNPs) in the management of patients with IPF.	TOLLIP MUC5B	4.84e-06	2	77	2	33639995
Pubmed	Control of bone resorption in mice by Schnurri-3.	HIVEP3 NFATC1	4.84e-06	2	77	2	22573816
Pubmed	Cloning and characterization of a second complementary DNA for human tryptase.	TPSAB1 TPSB2	4.84e-06	2	77	2	2203827
Pubmed	Rationale for targeting BCL6 in MLL-rearranged acute lymphoblastic leukemia.	KMT2A BCL6	4.84e-06	2	77	2	31395741
Pubmed	Telomere length and genetic variant associations with interstitial lung disease progression and survival.	TOLLIP MUC5B	4.84e-06	2	77	2	30635297
Pubmed	Characterization of two highly polymorphic human tryptase loci and comparison with a newly discovered monkey tryptase ortholog.	TPSAB1 TPSB2	4.84e-06	2	77	2	10898108
Pubmed	TOLLIP, MUC5B, and the Response to N-Acetylcysteine among Individuals with Idiopathic Pulmonary Fibrosis.	TOLLIP MUC5B	4.84e-06	2	77	2	26331942
Pubmed	Association of structural polymorphisms in the human period3 gene with delayed sleep phase syndrome.	PER3 PER1	4.84e-06	2	77	2	11306557
Pubmed	Set1 and MLL1/2 Target Distinct Sets of Functionally Different Genomic Loci In Vivo.	KMT2D KMT2A	4.84e-06	2	77	2	26711341
Pubmed	Human beta-tryptase is a ring-like tetramer with active sites facing a central pore.	TPSAB1 TPSB2	4.84e-06	2	77	2	9521329
Pubmed	Human mast cell tryptase: multiple cDNAs and genes reveal a multigene serine protease family.	TPSAB1 TPSB2	4.84e-06	2	77	2	2187193
Pubmed	Mll2 is required for H3K4 trimethylation on bivalent promoters in embryonic stem cells, whereas Mll1 is redundant.	KMT2D KMT2A	4.84e-06	2	77	2	24423662
Pubmed	Structural requirements and mechanism for heparin-dependent activation and tetramerization of human betaI- and betaII-tryptase.	TPSAB1 TPSB2	4.84e-06	2	77	2	15567416
Pubmed	Nuclear import of mPER3 in Xenopus oocytes and HeLa cells requires complex formation with mPER1.	PER3 PER1	4.84e-06	2	77	2	16008569
Pubmed	Human tryptases alpha and beta/II are functionally distinct due, in part, to a single amino acid difference in one of the surface loops that forms the substrate-binding cleft.	TPSAB1 TPSB2	4.84e-06	2	77	2	10391906
Pubmed	The human mast cell tryptase tetramer: a fascinating riddle solved by structure.	TPSAB1 TPSB2	4.84e-06	2	77	2	10708850
Pubmed	Tryptase haplotype in mastocytosis: relationship to disease variant and diagnostic utility of total tryptase levels.	TPSAB1 TPSB2	4.84e-06	2	77	2	17449330
Pubmed	Impact of naturally forming human α/β-tryptase heterotetramers in the pathogenesis of hereditary α-tryptasemia.	TPSAB1 TPSB2	4.84e-06	2	77	2	31337736
Pubmed	Polymorphisms in period genes and bone response to hormone therapy in postmenopausal Korean women.	PER3 PER1	4.84e-06	2	77	2	26624862
Pubmed	Osteoclastic expression of higher-level regulators NFATc1 and BCL6 in medication-related osteonecrosis of the jaw secondary to bisphosphonate therapy: a comparison with osteoradionecrosis and osteomyelitis.	NFATC1 BCL6	4.84e-06	2	77	2	30832685
Pubmed	Expression profiles of PERIOD1, 2, and 3 in peripheral blood mononuclear cells from older subjects.	PER3 PER1	1.45e-05	3	77	2	19013183
Pubmed	NFATc1 releases BCL6-dependent repression of CCR2 agonist expression in peritoneal macrophages from Saccharomyces cerevisiae infected mice.	NFATC1 BCL6	1.45e-05	3	77	2	26631626
Pubmed	A differential response of two putative mammalian circadian regulators, mper1 and mper2, to light.	PER3 PER1	1.45e-05	3	77	2	9428527
Pubmed	Low-Salt Diet and Circadian Dysfunction Synergize to Induce Angiotensin II-Dependent Hypertension in Mice.	PER3 PER1	1.45e-05	3	77	2	26781276
Pubmed	Two period homologs: circadian expression and photic regulation in the suprachiasmatic nuclei.	PER3 PER1	1.45e-05	3	77	2	9427249
Pubmed	Functional polymorphisms of circadian negative feedback regulation genes are associated with clinical outcome in hepatocellular carcinoma patients receiving radical resection.	PER3 PER1	1.45e-05	3	77	2	25344870
Pubmed	Association between polymorphisms in period genes and bone density in postmenopausal Korean women.	PER3 PER1	1.45e-05	3	77	2	24678593
Pubmed	Recurrent mutations in NF-κB pathway components, KMT2D, and NOTCH1/2 in ocular adnexal MALT-type marginal zone lymphomas.	KMT2D NOTCH2	1.45e-05	3	77	2	27566587
Pubmed	Photic entrainment of period mutant mice is predicted from their phase response curves.	PER3 PER1	1.45e-05	3	77	2	20826680
Pubmed	Differential functions of mPer1, mPer2, and mPer3 in the SCN circadian clock.	PER3 PER1	1.45e-05	3	77	2	11395012
Pubmed	mPeriod2 Brdm1 and other single Period mutant mice have normal food anticipatory activity.	PER3 PER1	1.45e-05	3	77	2	29138421
Pubmed	A time memory engram embedded in a light-entrainable circadian clock.	PER3 PER1	1.45e-05	3	77	2	37951213
Pubmed	Influence of age on clock gene expression in peripheral blood cells of healthy women.	PER3 PER1	1.45e-05	3	77	2	19861640
Pubmed	Bimodal regulation of mPeriod promoters by CREB-dependent signaling and CLOCK/BMAL1 activity.	PER3 PER1	1.45e-05	3	77	2	12032351
Pubmed	Pygo2 functions as a prognostic factor for glioma due to its up-regulation of H3K4me3 and promotion of MLL1/MLL2 complex recruitment.	KMT2D KMT2A	1.45e-05	3	77	2	26902498
Pubmed	Deregulated expression of the PER1, PER2 and PER3 genes in breast cancers.	PER3 PER1	1.45e-05	3	77	2	15790588
Pubmed	Unwinding the differences of the mammalian PERIOD clock proteins from crystal structure to cellular function.	PER3 PER1	1.45e-05	3	77	2	22331899
Pubmed	Remodeling of the enhancer landscape during macrophage activation is coupled to enhancer transcription.	KMT2D KMT2A	1.45e-05	3	77	2	23932714
Pubmed	Aberrant expression of Per1, Per2 and Per3 and their prognostic relevance in non-small cell lung cancer.	PER3 PER1	1.45e-05	3	77	2	25550826
Pubmed	MLL histone methylases regulate expression of HDLR-SR-B1 in presence of estrogen and control plasma cholesterol in vivo.	KMT2D KMT2A	1.45e-05	3	77	2	23192982
Pubmed	A light-independent oscillatory gene mPer3 in mouse SCN and OVLT.	PER3 PER1	1.45e-05	3	77	2	9707434
Pubmed	Intracellular calcium mobilization induces period genes via MAP kinase pathways in NIH3T3 cells.	PER3 PER1	1.45e-05	3	77	2	11959112
Pubmed	Comparing expression levels of PERIOD genes PER1, PER2 and PER3 in chronic insomnia patients and medical staff working in the night shift.	PER3 PER1	1.45e-05	3	77	2	32805476
Pubmed	Sleep rhythmicity and homeostasis in mice with targeted disruption of mPeriod genes.	PER3 PER1	1.45e-05	3	77	2	15031135
Pubmed	Characterization of genes encoding known and novel human mast cell tryptases on chromosome 16p13.3.	TPSAB1 TPSB2	1.45e-05	3	77	2	9920877
Pubmed	Nuclear export of mammalian PERIOD proteins.	PER3 PER1	1.45e-05	3	77	2	11591712
Pubmed	Cooperative interaction between GATA5 and NF-ATc regulates endothelial-endocardial differentiation of cardiogenic cells.	NFATC1 GATA5	1.45e-05	3	77	2	12163407
Pubmed	Period determination in the food-entrainable and methamphetamine-sensitive circadian oscillator(s).	PER3 PER1	1.45e-05	3	77	2	22891330
Pubmed	The role of phosphorylation and degradation of hPER protein oscillation in normal human fibroblasts.	PER3 PER1	1.45e-05	3	77	2	14712925
Pubmed	Immunohistochemical expression of Mum-1, Oct-2 and Bcl-6 in systemic anaplastic large cell lymphomas.	POU2F2 BCL6	1.45e-05	3	77	2	22158496
Pubmed	Period Family of Clock Genes as Novel Predictors of Survival in Human Cancer: A Systematic Review and Meta-Analysis.	PER3 PER1	1.45e-05	3	77	2	32849922
Pubmed	Human subjects are protected from mast cell tryptase deficiency despite frequent inheritance of loss-of-function mutations.	TPSAB1 TPSB2	1.45e-05	3	77	2	19748655
Pubmed	Distinct pathways affected by menin versus MLL1/MLL2 in MLL-rearranged acute myeloid leukemia.	KMT2D KMT2A	1.45e-05	3	77	2	30315824
Pubmed	Circadian clock regulates hepatic polyploidy by modulating Mkp1-Erk1/2 signaling pathway.	PER3 PER1	1.45e-05	3	77	2	29269828
Pubmed	The complex relationship between the light-entrainable and methamphetamine-sensitive circadian oscillators: evidence from behavioral studies of Period-mutant mice.	PER3 PER1	1.45e-05	3	77	2	23869717
Pubmed	An hPer2 phosphorylation site mutation in familial advanced sleep phase syndrome.	PER3 PER1	2.89e-05	4	77	2	11232563
Pubmed	Molecular analysis of mammalian timeless.	PER3 PER1	2.89e-05	4	77	2	9856466
Pubmed	Carm1 regulates Pax7 transcriptional activity through MLL1/2 recruitment during asymmetric satellite stem cell divisions.	KMT2D KMT2A	2.89e-05	4	77	2	22863532
Pubmed	Notch suppresses nuclear factor of activated T cells (NFAT) transactivation and Nfatc1 expression in chondrocytes.	NFATC1 NOTCH2	2.89e-05	4	77	2	23264614
Pubmed	Endotoxin Disrupts Circadian Rhythms in Macrophages via Reactive Oxygen Species.	PER3 PER1	2.89e-05	4	77	2	27168152
Pubmed	KDM5A noncanonically binds antagonists MLL1/2 to mediate gene regulation and promotes epithelial to mesenchymal transition.	KMT2D KMT2A	2.89e-05	4	77	2	37722486
Pubmed	A subset of mixed lineage leukemia proteins has plant homeodomain (PHD)-mediated E3 ligase activity.	KMT2D KMT2A	2.89e-05	4	77	2	23129768
Pubmed	Functional consequences of a CKIdelta mutation causing familial advanced sleep phase syndrome.	PER3 PER1	2.89e-05	4	77	2	15800623
Pubmed	Regulation of clock genes.	PER3 PER1	2.89e-05	4	77	2	10487202
Pubmed	Cloning and characterization of rat casein kinase 1epsilon.	PER3 PER1	2.89e-05	4	77	2	10899319
Pubmed	A splice variant of human ephrin-A4 encodes a soluble molecule that is secreted by activated human B lymphocytes.	EPHA6 EPHA2	2.89e-05	4	77	2	10607706
Pubmed	The circadian clock protein Period 1 regulates expression of the renal epithelial sodium channel in mice.	PER3 PER1	2.89e-05	4	77	2	19587447
Pubmed	The MLL3/MLL4 branches of the COMPASS family function as major histone H3K4 monomethylases at enhancers.	KMT2D KMT2A	2.89e-05	4	77	2	24081332
Pubmed	Expression of basic helix-loop-helix/PAS genes in the mouse suprachiasmatic nucleus.	PER3 PER1	2.89e-05	4	77	2	10077321
Pubmed	Comparison of β-adrenergic and glucocorticoid signaling on clock gene and osteoblast-related gene expressions in human osteoblast.	PER3 PER1	2.89e-05	4	77	2	22217103
Pubmed	The ins and outs of circadian timekeeping.	PER3 PER1	2.89e-05	4	77	2	10508692
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	BAZ2A ZFR2 DENND4B KATNIP ANKRD12 ARHGEF17 TENM2	3.39e-05	407	77	7	12693553
Pubmed	Tbr1 regulates regional and laminar identity of postmitotic neurons in developing neocortex.	EPHA6 ETV1 BCL6	3.66e-05	29	77	3	20615956
Pubmed	Mammalian circadian autoregulatory loop: a timeless ortholog and mPer1 interact and negatively regulate CLOCK-BMAL1-induced transcription.	PER3 PER1	4.82e-05	5	77	2	9856465
Pubmed	Evolving Catalytic Properties of the MLL Family SET Domain.	KMT2D KMT2A	4.82e-05	5	77	2	26320581
Pubmed	Disturbance of circadian gene expression in hepatocellular carcinoma.	PER3 PER1	4.82e-05	5	77	2	18444243
Pubmed	Intercellular coupling confers robustness against mutations in the SCN circadian clock network.	PER3 PER1	4.82e-05	5	77	2	17482552
Pubmed	Control of intracellular dynamics of mammalian period proteins by casein kinase I epsilon (CKIepsilon) and CKIdelta in cultured cells.	PER3 PER1	4.82e-05	5	77	2	11865049
Pubmed	MLL2, Not MLL1, Plays a Major Role in Sustaining MLL-Rearranged Acute Myeloid Leukemia.	KMT2D KMT2A	4.82e-05	5	77	2	28609655
Pubmed	Correlation between circadian gene variants and serum levels of sex steroids and insulin-like growth factor-I.	PER3 PER1	4.82e-05	5	77	2	18990770
Pubmed	Characterization of human gamma-tryptases, novel members of the chromosome 16p mast cell tryptase and prostasin gene families.	TPSAB1 TPSB2	4.82e-05	5	77	2	10843716
Pubmed	The Chromatin Regulator Mll1 Supports T Follicular Helper Cell Differentiation by Controlling Expression of Bcl6, LEF-1, and TCF-1.	KMT2A BCL6	4.82e-05	5	77	2	37074193
Pubmed	B-cell transcription factors Pax-5, Oct-2, BOB.1, Bcl-6, and MUM1 are useful markers for the diagnosis of nodular lymphocyte predominant Hodgkin lymphoma.	POU2F2 BCL6	4.82e-05	5	77	2	21424034
Pubmed	Variants in circadian genes and prostate cancer risk: a population-based study in China.	PER3 PER1	4.82e-05	5	77	2	17984998
Pubmed	Dimerization and nuclear entry of mPER proteins in mammalian cells.	PER3 PER1	4.82e-05	5	77	2	10837028
Pubmed	Fine-scale comparative mapping of the human 7q11.23 region and the orthologous region on mouse chromosome 5G: the low-copy repeats that flank the Williams-Beuren syndrome deletion arose at breakpoint sites of an evolutionary inversion(s).	POM121 POM121C POM121B	6.49e-05	35	77	3	11013070
Pubmed	A molecular mechanism regulating rhythmic output from the suprachiasmatic circadian clock.	PER3 PER1	7.22e-05	6	77	2	9989497
Pubmed	Molecular bases for circadian clocks.	PER3 PER1	7.22e-05	6	77	2	9988221
Pubmed	Macromolecular Assemblies of the Mammalian Circadian Clock.	PER3 PER1	7.22e-05	6	77	2	28886335
GeneFamily	Fibronectin type III domain containing\|Sterile alpha motif domain containing\|EPH receptors	EPHA6 EPHA2	7.22e-04	14	52	2	1095
GeneFamily	PHD finger proteins	KMT2D BAZ2A KMT2A	2.21e-03	90	52	3	88
GeneFamily	Guanylate cyclase receptors\|DENN/MADD domain containing	DENND4B DENND1A	2.33e-03	25	52	2	504
GeneFamily	Zinc fingers C2H2-type\|Lysine methyltransferases\|PR/SET domain family	KMT2D KMT2A	4.29e-03	34	52	2	487
GeneFamily	Zinc fingers CCCH-type	ZC3H7B MBNL3	4.54e-03	35	52	2	73
ToppCell	Frontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Parm1\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	TPSAB1 EPHA6 BCL6 C4orf54 TPSB2	1.34e-06	111	76	5	1847dde68d349114286bc3317be6339666df4aa2
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MAST4 EPHA6 BCL6 ADAMTSL3 WWC1	1.85e-05	190	76	5	1cf023e3c6924d6a06f353d4b62444b6f2fee8a7
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Ascending_Thin_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MAST4 EPHA6 BCL6 ADAMTSL3 WWC1	1.85e-05	190	76	5	59bbbd2c8d4b7ce46c54ca8022b1557e7e5eee2a
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	MAST4 EPHA2 ARHGAP44 ETV1 WWC1	1.89e-05	191	76	5	34cc997e4e5c727495f321e6807a84aa124da486
ToppCell	LPS_only\|World / Treatment groups by lineage, cell group, cell type	MAST4 EPHA2 SLC25A47 BCL6 RBM38	2.30e-05	199	76	5	852cf595c2255983cff9045f2bb746d4391cf5ba
ToppCell	Parenchymal-10x3prime_v2-Immune_Myeloid-Myeloid-Megakaryocyte\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	TPSAB1 PER1 KMT2A TPSB2 RBM38	2.36e-05	200	76	5	0d76b006d8e8b32174e65e400acd0674354b962c
ToppCell	Parenchymal-10x3prime_v2-Immune_Myeloid-Myeloid\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	TPSAB1 PER1 KMT2A TPSB2 RBM38	2.36e-05	200	76	5	cc8368665bc6bb7c4f39632ccff07ceaa98a7b65
ToppCell	E18.5-samps-Mesenchymal-Pericyte-pericyte_B\|E18.5-samps / Age Group, Lineage, Cell class and subclass	NEU4 FA2H ADAMTSL3 SH2B1	1.30e-04	151	76	4	8ba15ab24fe2e71df0a2a7511ca451ad2376bd91
ToppCell	18-Airway-Epithelial-Goblet-like_secretory\|Airway / Age, Tissue, Lineage and Cell class	MUC5B TIGD5 POM121C WNK2	1.36e-04	153	76	4	14a60220e169ce642771636de982a7b02e5b2608
ToppCell	saliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	POU2F2 HDAC10 ZC3H7B RBM38	1.47e-04	156	76	4	a5930b455e5c8586c43c50106ab4d8a1e5e9e3d6
ToppCell	BAL-Mild-cDC_5\|Mild / Compartment, Disease Groups and Clusters	ADAMTS10 XYLT2 EPHA2 PER1	1.66e-04	161	76	4	7a6e8ed0b5d999efce8945d8083ab01d71be9a92
ToppCell	IIF-Other-HSPC\|IIF / Disease, Lineage and Cell Type	TPSAB1 MAMLD1 ARHGEF17 TPSB2	1.74e-04	163	76	4	1e0d38fbed38ac48478868a1480172a1a3f7c1b7
ToppCell	(08)_PNEC-(4)_1wkpi\|(08)_PNEC / shred by cell type and Timepoint	SH2B1 RBM38	1.84e-04	12	76	2	f1b105bcdbe03be6765c820b42c752a24d502212
ToppCell	5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ADAMTS10 MUC5B INPP5J WNK2	1.86e-04	166	76	4	60060b03f2abfa3cc08107ab5a9f578e60e4ae16
ToppCell	5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ADAMTS10 MUC5B INPP5J WNK2	1.86e-04	166	76	4	ec9161d388db5a257b8d125c14f9dd911d5d5d4a
ToppCell	5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)-\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ADAMTS10 MUC5B INPP5J WNK2	1.86e-04	166	76	4	4586d6725403f879fc96f67be579022587ce1906
ToppCell	TCGA-Bile_Duct-Primary_Tumor-Cholangiocarcinoma-Intrahepatic-2\|TCGA-Bile_Duct / Sample_Type by Project: Shred V9	ADAMTS10 SERGEF SH3RF3 NOTCH2	1.95e-04	168	76	4	c70bf73bb800e4722cedc35bbc17ea3113d1012d
ToppCell	3'-Parenchyma_lung-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells-Mast_cells_L.1.4.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TPSAB1 ADAMTSL3 TPSB2 RBM38	1.95e-04	168	76	4	55f328353119cbdc521c782ebb8d163876f4186d
ToppCell	droplet-Heart-nan\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTS10 PER1 BCL6 NOTCH2	2.00e-04	169	76	4	2e5bb6437bc9c614e337c5ffb6f6457cd9fc7f4c
ToppCell	3'-GW_trimst-2-LargeIntestine-Epithelial-epithelial_progenitor_cell\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NUTM1 NEU4 EPHA2 MUC5B	2.09e-04	171	76	4	3ef44a5e3e8f81424f1e9aa302860b6688a549b8
ToppCell	3'-GW_trimst-2-LargeIntestine-Epithelial-epithelial_progenitor_cell-Stem_cells\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NUTM1 NEU4 EPHA2 MUC5B	2.09e-04	171	76	4	3a2fefcb62e9d47ae6b3a946c45d3f2dd32c576c
ToppCell	Multiple_Sclerosis-Lymphocyte-T_NK-ILC\|Multiple_Sclerosis / Disease, Lineage and Cell Type	ZGRF1 PRR22 AGRN WWC1	2.23e-04	174	76	4	7c50bf9da37711266cc077eef4e54b58463f1d37
ToppCell	3'-GW_trimst-2-SmallIntestine-Epithelial-mature_enterocytic-Paneth\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MUC5B FOXH1 PLXNB1 SEPTIN12	2.28e-04	175	76	4	24651f95540ea2c8f3720aa943cbdd15661ee3fa
ToppCell	facs-Liver-Liver_non-hepato/SCs_st-18m-Lymphocytic-B_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	POU2F2 TPSB2 NOTCH2 RBM38	2.33e-04	176	76	4	0f056597bc9e53176ce8670924ac925c801964b5
ToppCell	droplet-Lung-3m-Mesenchymal-myofibroblast-pericyte_cell-pericyte\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NID2 ADAMTSL3 ARHGEF17 PLXNB1	2.33e-04	176	76	4	e2b59a904c5c8f9c88e1e63788e9b6485f22edd0
ToppCell	droplet-Lung-3m-Mesenchymal-myofibroblast-pericyte_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NID2 ADAMTSL3 ARHGEF17 PLXNB1	2.33e-04	176	76	4	f931192e3cc65414e2245354f443473696cc7ce8
ToppCell	facs-Liver-Liver_non-hepato/SCs_st-18m-Lymphocytic-B_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	POU2F2 TPSB2 NOTCH2 RBM38	2.33e-04	176	76	4	d04be5acf0be46adc3d2055f6f21358c02792817
ToppCell	droplet-Lung-nan-3m-Mesenchymal-pericyte_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NID2 ADAMTSL3 ARHGEF17 PLXNB1	2.38e-04	177	76	4	65709bd546cb1ec6aa2ddd8b2adb46e174eb9a9a
ToppCell	droplet-Lung-nan-3m-Mesenchymal-Pericyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NID2 ADAMTSL3 ARHGEF17 PLXNB1	2.38e-04	177	76	4	8684d47a547e2a06496f15e8da0200ecddc431e0
ToppCell	facs-Lung-18m-Mesenchymal-myofibroblast-pericyte_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NID2 ADAMTSL3 ARHGEF17 PLXNB1	2.43e-04	178	76	4	8bae5db100f4563aa1fc7f881e7f8c59d669e37a
ToppCell	facs-Large_Intestine-Proximal-18m-Epithelial-Brush_cell_of_epithelium_proper_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NFATC1 INPP5J WNK2 RBM38	2.43e-04	178	76	4	09a215a0d6e98e4bb920cabda12af08ff4de3c98
ToppCell	PND28-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ARHGAP44 SH3RF3 AGRN WWC1	2.43e-04	178	76	4	a3af5d9c55858e36be0498081029ecb0acaeb3d3
ToppCell	facs-Lung-18m-Mesenchymal-myofibroblast-pericyte_cell-pericyte\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NID2 ADAMTSL3 ARHGEF17 PLXNB1	2.43e-04	178	76	4	bc0336692b84bd0fa49747ed5a031b8ed8afa0fd
ToppCell	PND28-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ARHGAP44 SH3RF3 AGRN WWC1	2.43e-04	178	76	4	b3b88989bd602cfb55bb5c47731deb99288a8952
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	EPHA2 MUC5B BCL6 WNK2	2.49e-04	179	76	4	6e965e424eebef50f0202cff75f458be395cfca1
ToppCell	facs-Lung-nan-3m-Mesenchymal-Pericyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NID2 ADAMTSL3 ARHGEF17 PLXNB1	2.49e-04	179	76	4	7078022e60faa86444f2a2c6eb9f767cc66b5cfa
ToppCell	facs-Lung-nan-3m-Mesenchymal-pericyte_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NID2 ADAMTSL3 ARHGEF17 PLXNB1	2.49e-04	179	76	4	d4a975d8ffa5e77fb5c0ec05bf9c8f843c77ce07
ToppCell	5'-GW_trimst-2-LargeIntestine-Hematopoietic-Myeloid-CLC+_Mast_cell\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TPSAB1 DENND4B POU2F2 TPSB2	2.59e-04	181	76	4	338c7362d258a87f1a6b1a65376f5394d4b2b4b2
ToppCell	droplet-Lung-LUNG-1m-Mesenchymal-pericyte_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NID2 ADAMTSL3 ARHGEF17 PLXNB1	2.65e-04	182	76	4	9edaccf1154cec92ca9a28e9b1f9075cfd422bfd
ToppCell	5'-Airway_Nasal-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells-\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TPSAB1 MAMLD1 E2F7 TPSB2	2.65e-04	182	76	4	4cd5eb13f78f4f377932c50ac2acb4ac0cd14c12
ToppCell	droplet-Lung-LUNG-1m-Mesenchymal-Pericyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NID2 ADAMTSL3 ARHGEF17 PLXNB1	2.65e-04	182	76	4	aba4c06d5d7618ac21b2695bca8e7a1346a91090
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ARHGAP44 NPAP1 ADAMTSL3 C4orf54	2.70e-04	183	76	4	b5ede5a0048c585b73c00e88aeddbcaf669347b1
ToppCell	COVID-19-Epithelial_cells-AT2\|COVID-19 / group, cell type (main and fine annotations)	MAST4 ARHGAP44 ETV1 WWC1	2.76e-04	184	76	4	369b82f793deab672204558ae4e112cfa5aa9ccc
ToppCell	droplet-Lung-1m-Mesenchymal-myofibroblast-pericyte_cell-pericyte\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NID2 ADAMTSL3 ARHGEF17 PLXNB1	2.76e-04	184	76	4	4cb5f299dd7413e0be1ad7af817ee614b23a18ae
ToppCell	COVID-19-Heart-Pericyte\|Heart / Disease (COVID-19 only), tissue and cell type	ARHGAP44 PLEKHG2 ADAMTSL3 ARHGEF17	2.76e-04	184	76	4	21790cdfa3b4036ad413fd44b94e31563116f25f
ToppCell	droplet-Lung-1m-Mesenchymal-myofibroblast-pericyte_cell\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NID2 ADAMTSL3 ARHGEF17 PLXNB1	2.76e-04	184	76	4	39bb0eb55bdc2cea46e41c7f21d8c5883f14e6bd
ToppCell	Control-Epithelial-Goblet\|World / Disease state, Lineage and Cell class	MAST4 EPHA2 MUC5B WNK2	2.82e-04	185	76	4	9a793e6016295a63820e9d7563f195494ac692e7
ToppCell	COVID-19-Epithelial_cells-Airway_club\|COVID-19 / group, cell type (main and fine annotations)	MAST4 ARHGAP44 WNK2 WWC1	2.82e-04	185	76	4	cfe6fd73d817e173fe803bc1683c291d9bcb8608
ToppCell	(00)_Basal-(4)_1wkpi\|(00)_Basal / shred by cell type and Timepoint	PER3 EPHA2 PER1 ANKRD12	2.82e-04	185	76	4	bf82ba905e5eee1c39a2731702071d3de10a78b8
ToppCell	COPD-Epithelial-Goblet\|World / Disease state, Lineage and Cell class	MAST4 EPHA2 MUC5B WNK2	2.88e-04	186	76	4	d75fe7640a4b2c450c9759a1b3c3ef2a087f0092
ToppCell	Tuft\|World / Class top	NFATC1 ETV1 INPP5J WNK2	2.88e-04	186	76	4	f4d83f15ab7b49c0920a322cd832413ece7c9948
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	MAST4 ARHGAP44 ETV1 WWC1	2.88e-04	186	76	4	acfa68a2afb7d2b51c9b469a1965fe5cc5d5e64e
ToppCell	368C-Myeloid-Dendritic-cDC_proliferating_1\|Dendritic / Donor, Lineage, Cell class and subclass (all cells)	XYLT2 NEU4 ZGRF1 E2F7	2.88e-04	186	76	4	5cadab3271fce9ab6da3d7ba9827b8a221cac166
ToppCell	droplet-Fat-SCAT-30m-Epithelial\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PER3 MUC5B INPP5J PLXNB1	2.94e-04	187	76	4	5fada3c5a58c1890029ccbfff2608b33f8cd2df7
ToppCell	droplet-Fat-SCAT-30m-Epithelial-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PER3 MUC5B INPP5J PLXNB1	2.94e-04	187	76	4	766e808138fc2cd623c2e6d57fcb5c7378da0e03
ToppCell	Children_(3_yrs)-Mesenchymal-pericyte_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ADAMTS10 ADAMTSL3 ARHGEF17 WNK2	2.94e-04	187	76	4	86250acf088ec0c4800a0dfa031b0d4f7e52c342
ToppCell	droplet-Fat-SCAT-30m-Epithelial-epithelial_cell\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PER3 MUC5B INPP5J PLXNB1	2.94e-04	187	76	4	f49d06600060deeb2fc1b1da5b93496535f20104
ToppCell	Tuft-tuft-2\|World / Class top	NFATC1 ETV1 INPP5J WNK2	2.94e-04	187	76	4	4ec6eee866619dfe13c84f5d2e812bb380d37139
ToppCell	Control-Fibroblasts-Other_FB\|Control / group, cell type (main and fine annotations)	EPHA6 ADAMTSL3 SH3RF3 TENM2	2.94e-04	187	76	4	bd3739c4a52aa1ba5deffd778e113a9800f7e158
ToppCell	3'-Child09-12-SmallIntestine-Hematopoietic-B_cells-DZ_GC_cell\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NFATC1 POU2F2 ZNF581 RBM38	3.00e-04	188	76	4	9a10536afa2dea34c78421d36564cfd8252afe45
ToppCell	LPS-IL1RA-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MAST4 ARHGAP44 ETV1 WWC1	3.00e-04	188	76	4	4bdf8d49af0e9da349b16e3f012e1b0eec04cc4f
ToppCell	COPD-Multiplet-Multiplet\|World / Disease state, Lineage and Cell class	TPSAB1 MAST4 TPSB2 WWC1	3.00e-04	188	76	4	186fe1ea328c942910190a4240262c0d8642ea3b
ToppCell	metastatic_Lymph_Node-Myeloid_cells-Undetermined\|Myeloid_cells / Location, Cell class and cell subclass	TPSAB1 MAST4 TPSB2 WWC1	3.06e-04	189	76	4	b46adb47768a7b6d801c457d7ba65508edfc36a5
ToppCell	droplet-Lung-LUNG-1m-Mesenchymal-bronchial_smooth_muscle_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGAP44 ETV1 SLC25A47 INPP5J	3.06e-04	189	76	4	4dc32b463546bbe7250dddd281b92ad17ec22da1
ToppCell	droplet-Lung-LUNG-1m-Mesenchymal-Airway_Smooth_Muscle\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGAP44 ETV1 SLC25A47 INPP5J	3.06e-04	189	76	4	0d06bf0d7191d13a1c4f30a7881e7ea1093bfd6f
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	MAST4 EPHA2 ARHGAP44 WWC1	3.12e-04	190	76	4	8aea807a2bcf0b653b4de6202b6ecb0f0683cc2e
ToppCell	Control-Epithelial-ATII\|Control / Disease state, Lineage and Cell class	MAST4 EPHA2 ETV1 WWC1	3.12e-04	190	76	4	d50902a3abcc18aafa36d83cc2c6e07d7f7cb197
ToppCell	BAL-Control-Lymphocyte-B-B_cell\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	HIVEP3 NFATC1 PLEKHG2 RBM38	3.12e-04	190	76	4	da7341a8a423e5fe4d8e733d8e50c10a3318ac1c
ToppCell	Globus_pallidus-Neuronal\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	EPHA6 KMT2A ANKRD12 TENM2	3.12e-04	190	76	4	416de85d8841dac883faa6f5339b2fb461a09e82
ToppCell	BAL-Control-Lymphocyte-B-B_cell-B_cell\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	HIVEP3 NFATC1 PLEKHG2 RBM38	3.12e-04	190	76	4	42312f7d79fe889397d32910b625793e2535cc26
ToppCell	human_hepatoblastoma-Endothelial_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	HIVEP3 NID2 MAST4 NFATC1	3.12e-04	190	76	4	8d6ef93d69e96cd6921816d152bea3b0710cf147
ToppCell	BAL-Control-Lymphocyte-B-B_cell-B_cell-B_activate-7\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	HIVEP3 NFATC1 PLEKHG2 RBM38	3.12e-04	190	76	4	682418a7a2096743112eae3790d40e7e600612c0
ToppCell	IPF-Epithelial-Goblet\|IPF / Disease state, Lineage and Cell class	MAST4 EPHA2 MUC5B WNK2	3.12e-04	190	76	4	e41dd5a997ad9952810ffecb57737c03ea1d88b3
ToppCell	Children_(3_yrs)-Epithelial-club_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	MAST4 EPHA2 WNK2 WWC1	3.18e-04	191	76	4	23776c7302cead3881b39127398f3b3e0d27885e
ToppCell	COVID-19-lung-AT2\|lung / Disease (COVID-19 only), tissue and cell type	MAST4 ARHGAP44 ETV1 WWC1	3.18e-04	191	76	4	276455a64c2c3503d5048615762eb2ee37f0ac70
ToppCell	COPD-Epithelial-Goblet\|COPD / Disease state, Lineage and Cell class	FA2H EPHA2 MUC5B WNK2	3.24e-04	192	76	4	93b2ca0a97776d28c7e8f1a0642c4b63a5554aab
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	MAST4 ARHGAP44 ETV1 WWC1	3.24e-04	192	76	4	fb2f0e897228f808d9ff734ad05e9b49dc38fa50
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-AC-like-AC-like_Prolif-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	MAST4 MAMLD1 E2F7 KMT2A	3.24e-04	192	76	4	d6f656be2698bd215717d35f4e7ab727c08c61e0
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	HIVEP3 MAMLD1 ADAMTSL3 TENM2	3.31e-04	193	76	4	b3ad5ff480d99217f36cc7471e5a96a519ddb409
ToppCell	ASK440-Epithelial-Secretory\|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq	EPHA2 MUC5B PLXNB1 WNK2	3.31e-04	193	76	4	50e98d91697c7af6a3de39e52edde6dd2b67b512
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTSL3 AGRN C4orf54 INPP5J	3.31e-04	193	76	4	e7012f7b53971972299db34fa51ff51a4e4987fe
ToppCell	COVID-19_Mild\|World / Disease condition and Cell class	PER1 N4BP1 ANKRD12 RBM38	3.31e-04	193	76	4	7256a5a491536c525b31ae96d47ab5c6303cb73a
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTSL3 AGRN C4orf54 INPP5J	3.37e-04	194	76	4	be869e186386d03ebb670971dd24fa656b4b0edf
ToppCell	10x_3'_v2v3-Non-neoplastic-Lymphoid-B_cell-B_cell-F\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	NFATC1 ZGRF1 MAMLD1 KATNIP	3.37e-04	194	76	4	9a99abc65e7509e7ae8fb392f5ee4b2a83128072
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTSL3 AGRN C4orf54 INPP5J	3.37e-04	194	76	4	4d6c9b016e3a0641954a8ea10c97d1cd76fadd9f
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-Secretory/RAS\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MAST4 EPHA2 WNK2 WWC1	3.37e-04	194	76	4	0cd4363627acd419e00d6d32f6dce10430aa6487
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-SMC_prolif-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	NID2 ARHGAP44 ADAMTSL3 ARHGEF17	3.37e-04	194	76	4	78dcb9d48259afabe73b41c5508a73a8d62339a4
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-Secretory/RAS-RAS\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MAST4 EPHA2 WNK2 WWC1	3.37e-04	194	76	4	a58841b34efe673671a9a059238e044a7254b279
ToppCell	5'-Parenchyma_lung-Immune_Myeloid-Myeloid_monocytic-non-classical_monocyte-Non-classical_monocytes-Non-classical_monocytes_L.1.2.2.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	POU2F2 PLEKHG2 DENND1A NOTCH2	3.37e-04	194	76	4	dfe0ece81922bfd7c6673726d3ea2365cbdb5513
ToppCell	3'-Child04-06-SmallIntestine-Hematopoietic-B_cells-DZ_GC_cell\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	POU2F2 ZNF581 BCL6 RBM38	3.44e-04	195	76	4	bf750c516e67c45c6b511909dcff934168a7bbef
ToppCell	Children_(3_yrs)-Epithelial-club_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	MAST4 EPHA2 WNK2 WWC1	3.44e-04	195	76	4	dccc32fcf772e2504de7f663ef0a5bd8e23e92fc
ToppCell	Bronchial-NucSeq-Epithelial-Epi_airway_secretory\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PRR22 MUC5B WNK2 WWC1	3.44e-04	195	76	4	e7230a849ea31e6eef9bc6f5468938499450582d
ToppCell	Control-Epithelial\|Control / Disease state, Lineage and Cell class	MAST4 EPHA2 ARHGAP44 WWC1	3.44e-04	195	76	4	1798c3b89b1b5ff4f5777d2b9f52dc81cdad28fa
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Scavenging_pericyte\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	NID2 ARHGAP44 ADAMTSL3 ARHGEF17	3.51e-04	196	76	4	cb61757646653f89faba503cb5d99e5dd5197b4c
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Scavenging_pericyte-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	NID2 ARHGAP44 ADAMTSL3 ARHGEF17	3.51e-04	196	76	4	44e2df1b61e3819eae7e482bef0a733afe852d67
ToppCell	B_cells-Naive_B_cells_\|B_cells / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	NFATC1 PER1 FAM53C RBM38	3.58e-04	197	76	4	fd5fdc5289d681d59ff22d72e4de6e74c6c7aac6
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	NID2 NFATC1 MAMLD1 SH3RF3	3.58e-04	197	76	4	85a8f1d18e0dd1d31341f5131eecd217553bf042
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	NID2 NFATC1 MAMLD1 SH3RF3	3.58e-04	197	76	4	e8e3ba791dfaa0fab35e0329a5e34376f9ee6143
ToppCell	5'-Adult-Distal_Rectal-Epithelial-epithelial_progenitor_cell-TA\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NEU4 MUC5B PLXNB1 WNK2	3.58e-04	197	76	4	e14a0e8a893c72356afc5508e3531ae0b23bfe16
ToppCell	LPS_only-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS_only / Treatment groups by lineage, cell group, cell type	EPHA2 ETV1 PLXNB1 WWC1	3.58e-04	197	76	4	1a1bee8da6e04b65935c40373eaee4d6c046d9a1
Drug	Fluorocurarine chloride [22273-09-2]; Up 200; 11.6uM; MCF7; HT_HG-U133A	BAZ2A TBC1D5 PER1 ANKRD12 ZC3H7B AGRN NOTCH2	3.28e-06	197	73	7	6219_UP
Drug	PHA-00745360 [351320-33-7]; Up 200; 1uM; MCF7; HT_HG-U133A	PER3 BAZ2A PER1 ETV1 POM121L2 ARHGEF17 INPP5J	3.39e-06	198	73	7	4384_UP
Drug	Nimodipine [66085-59-4]; Down 200; 9.6uM; MCF7; HT_HG-U133A	EPHA2 TBC1D5 ZC3H7B ARHGEF17 SH2B1 PLXNB1 NOTCH2	3.51e-06	199	73	7	5421_DN
Drug	thymidine glycol monophosphate	TPSAB1 TPSB2	3.04e-05	3	73	2	CID000165415
Drug	Betamethasone [378-44-9]; Up 200; 10.2uM; PC3; HT_HG-U133A	BAZ2A ETV1 POM121L2 BCL6 ZC3H7B ARHGEF17	3.54e-05	192	73	6	6728_UP
Drug	STOCK1N-28457; Down 200; 20uM; MCF7; HT_HG-U133A	HIVEP3 TBC1D5 PER1 MUC5B BCL6 MBNL3	3.65e-05	193	73	6	6869_DN
Drug	Mexiletine hydrochloride [5370-01-4]; Down 200; 18.6uM; PC3; HT_HG-U133A	NID2 MAST4 NFATC1 BAZ2A ZC3H7B FAM53C	3.65e-05	193	73	6	4338_DN
Drug	Beta-Escin [11072-93-8]; Down 200; 3.2uM; PC3; HT_HG-U133A	PER3 TBC1D5 KATNIP BCL6 ZC3H7B PLXNB1	3.75e-05	194	73	6	3807_DN
Drug	Asiaticoside [16830-15-2]; Down 200; 4.2uM; MCF7; HT_HG-U133A	MAST4 EPHA2 ARHGAP44 ZC3H7B INPP5J NOTCH2	3.86e-05	195	73	6	3504_DN
Drug	Nitrocaramiphen hydrochloride; Up 200; 10.8uM; HL60; HT_HG-U133A	PER3 MAMLD1 ETV1 ZC3H7B ADAMTSL3 INPP5J	3.97e-05	196	73	6	3125_UP
Drug	Midodrine hydrochloride [3092-17-9]; Down 200; 13.8uM; HL60; HG-U133A	HIVEP3 BAZ2A N4BP1 ANKRD12 ZC3H7B NOTCH2	3.97e-05	196	73	6	1403_DN
Drug	Indapamide [26807-65-8]; Down 200; 10.6uM; MCF7; HT_HG-U133A	HIVEP3 BAZ2A N4BP1 ZC3H7B ADAMTSL3 ARHGEF17	3.97e-05	196	73	6	3970_DN
Drug	Pempidine tartrate [546-48-5]; Up 200; 13uM; PC3; HT_HG-U133A	BAZ2A PER1 KMT2A N4BP1 ARHGEF17 AGRN	3.97e-05	196	73	6	4307_UP
Drug	Pizotifen malate [5189-11-7]; Down 200; 9.4uM; PC3; HT_HG-U133A	XYLT2 MAST4 PER3 ETV1 KATNIP MUC5B	3.97e-05	196	73	6	5072_DN
Drug	Benserazide hydrochloride [14919-77-8]; Up 200; 13.6uM; PC3; HT_HG-U133A	XYLT2 BAZ2A POM121L2 POU2F2 N4BP1 ARHGEF17	4.09e-05	197	73	6	6722_UP
Drug	Aminohippuric acid [61-78-9]; Down 200; 20.6uM; MCF7; HT_HG-U133A	HIVEP3 BAZ2A EPHA2 ZC3H7B SH2B1 PLXNB1	4.09e-05	197	73	6	6453_DN
Drug	Trichlormethiazide [133-67-5]; Down 200; 10.6uM; MCF7; HT_HG-U133A	HIVEP3 BAZ2A EPHA2 PER1 N4BP1 ZC3H7B	4.09e-05	197	73	6	3337_DN
Drug	Pindolol [13523-86-9]; Down 200; 16.2uM; HL60; HG-U133A	HIVEP3 BAZ2A KMT2A N4BP1 BCL6 FAM53C	4.09e-05	197	73	6	1392_DN
Drug	Azapropazone [13539-59-8]; Up 200; 13.4uM; PC3; HT_HG-U133A	HIVEP3 FA2H PER1 ETV1 ZC3H7B WWC1	4.09e-05	197	73	6	7277_UP
Drug	trifluoperazine dihydrochloride; Down 200; 10uM; PC3; HT_HG-U133A	PER3 SERGEF N4BP1 ZC3H7B SH2B1 INPP5J	4.21e-05	198	73	6	4448_DN
Drug	Cephalexin monohydrate [23325-78-2]; Down 200; 11uM; PC3; HT_HG-U133A	HIVEP3 ETV1 N4BP1 BCL6 ZC3H7B NOTCH2	4.21e-05	198	73	6	4654_DN
Drug	Dexamethasone acetate [1177-87-3]; Up 200; 9.2uM; PC3; HT_HG-U133A	BAZ2A SERGEF PER1 POU2F2 N4BP1 AGRN	4.21e-05	198	73	6	5797_UP
Drug	Oxethazaine [126-27-2]; Down 200; 8.6uM; MCF7; HT_HG-U133A	EPHA2 KATNIP N4BP1 ZC3H7B PLXNB1 NOTCH2	4.33e-05	199	73	6	1484_DN
Drug	Methimazole [60-56-0]; Down 200; 35uM; MCF7; HT_HG-U133A	HIVEP3 PER1 POU2F2 ZC3H7B ARHGEF17 SH2B1	4.45e-05	200	73	6	4372_DN
Drug	Brunfelsamidine	TPSAB1 TPSB2	6.06e-05	4	73	2	CID005281683
Drug	Attpsa	TPSAB1 TPSB2	1.51e-04	6	73	2	CID005487511
Drug	Proscillaridin A [466-06-8]; Up 200; 7.6uM; MCF7; HT_HG-U133A	EPHA2 KMT2A POU2F2 ANKRD12 BCL6	1.64e-04	160	73	5	4404_UP
Drug	Digoxin [20830-75-5]; Up 200; 5.2uM; MCF7; HT_HG-U133A	BAZ2A EPHA2 ANKRD12 BCL6 FAM53C	1.95e-04	166	73	5	5324_UP
Drug	ioxaglate	TPSAB1 TPSB2	2.11e-04	7	73	2	CID000003742
Drug	Telebrix	TPSAB1 TPSB2	2.11e-04	7	73	2	CID000034536
Drug	daphnodorin C	TPSAB1 TPSB2	3.60e-04	9	73	2	CID000072428
Drug	LY 294002; Up 200; 10uM; MCF7; HT_HG-U133A	MAST4 TBC1D5 PER1 BCL6 AGRN	3.64e-04	190	73	5	6998_UP
Drug	Bupivacaine hydrochloride [18010-40-7]; Down 200; 12.4uM; MCF7; HT_HG-U133A	DAZAP1 ARHGAP44 KMT2A ZC3H7B WWC1	3.73e-04	191	73	5	7435_DN
Drug	Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; HL60; HT_HG-U133A	BAZ2A MAMLD1 ETV1 NOTCH2 WWC1	3.82e-04	192	73	5	2450_UP
Drug	estradiol, USP; Up 200; 0.01uM; MCF7; HT_HG-U133A	ARHGAP44 BCL6 AGRN MBNL3 WWC1	3.82e-04	192	73	5	5238_UP
Drug	Pramoxine hydrochloride [637-58-1]; Up 200; 12.2uM; PC3; HT_HG-U133A	ETV1 POM121L2 POU2F2 N4BP1 ZC3H7B	3.91e-04	193	73	5	3811_UP
Drug	Caffeic acid [3331-39-5]; Down 200; 22.2uM; PC3; HT_HG-U133A	HIVEP3 TBC1D5 SERGEF ETV1 PLXNB1	3.91e-04	193	73	5	6753_DN
Drug	Glimepiride [93479-97-1]; Down 200; 8.2uM; MCF7; HT_HG-U133A	BAZ2A TBC1D5 MAMLD1 PER1 RBM38	3.91e-04	193	73	5	4973_DN
Drug	Prednicarbate [73771-04-7]; Down 200; 8.2uM; PC3; HT_HG-U133A	MAST4 PER3 KMT2A N4BP1 WWC1	3.91e-04	193	73	5	5119_DN
Drug	Pimethixene maleate [13187-06-9]; Down 200; 9.8uM; MCF7; HT_HG-U133A	MAST4 BAZ2A MAMLD1 AGRN WWC1	4.01e-04	194	73	5	7468_DN
Drug	Iopromide [73334-07-3]; Up 200; 5uM; MCF7; HT_HG-U133A	TBC1D5 SERGEF PER1 ZC3H7B AGRN	4.01e-04	194	73	5	3481_UP
Drug	Harmalol hydrochloride dihydrate [6028-07-5]; Down 200; 14.6uM; PC3; HT_HG-U133A	SERGEF ETV1 KMT2A MUC5B N4BP1	4.01e-04	194	73	5	5076_DN
Drug	Pilocarpine nitrate [148-72-1]; Up 200; 14.8uM; PC3; HT_HG-U133A	ETV1 POM121L2 N4BP1 ZC3H7B MBNL3	4.01e-04	194	73	5	6741_UP
Drug	Imidurea [39236-46-9]; Down 200; 10.4uM; MCF7; HT_HG-U133A	EPHA2 KMT2A N4BP1 ZC3H7B INPP5J	4.01e-04	194	73	5	3522_DN
Drug	Mefloquine hydrochloride [51773-92-3]; Up 200; 9.6uM; HL60; HG-U133A	BAZ2A N4BP1 BCL6 ZC3H7B SH2B1	4.01e-04	194	73	5	1364_UP
Drug	Dihydroergotamine tartrate [5989-77-5]; Down 200; 3uM; PC3; HT_HG-U133A	HIVEP3 MAST4 PER3 BAZ2A NOTCH2	4.10e-04	195	73	5	4502_DN
Drug	Dicumarol [66-76-2]; Down 200; 11.8uM; MCF7; HT_HG-U133A	HIVEP3 KMT2A MUC5B N4BP1 PLXNB1	4.10e-04	195	73	5	3941_DN
Drug	Brinzolamide [138890-62-7]; Down 200; 10.4uM; PC3; HT_HG-U133A	XYLT2 NID2 PER3 ETV1 PLXNB1	4.10e-04	195	73	5	6670_DN
Drug	Sulfadiazine [68-35-9]; Down 200; 16uM; MCF7; HT_HG-U133A	BAZ2A EPHA2 KIAA0586 PER1 ZC3H7B	4.10e-04	195	73	5	1688_DN
Drug	Nabumetone [42924-53-8]; Down 200; 17.6uM; MCF7; HT_HG-U133A	MAST4 TBC1D5 ARHGEF17 MBNL3 WWC1	4.10e-04	195	73	5	5428_DN
Drug	Methoxamine hydrochloride [61-16-5]; Up 200; 16.2uM; MCF7; HT_HG-U133A	BAZ2A TBC1D5 PER1 ANKRD12 ZC3H7B	4.10e-04	195	73	5	4972_UP
Drug	Tranylcypromine hydrochloride [1986-47-6]; Down 200; 23.6uM; MCF7; HT_HG-U133A	HIVEP3 MAST4 PER1 ZC3H7B PLXNB1	4.10e-04	195	73	5	2264_DN
Drug	ST021200; Up 200; 10uM; PC3; HT_HG-U133A	XYLT2 MAST4 BAZ2A PER1 N4BP1	4.10e-04	195	73	5	7559_UP
Drug	radicicol; Down 200; 0.1uM; MCF7; HT_HG-U133A_EA	XYLT2 EPHA2 KMT2A BCL6 ZC3H7B	4.10e-04	195	73	5	953_DN
Drug	Amodiaquin dihydrochloride dihydrate [6398-98-7]; Up 200; 8.6uM; MCF7; HT_HG-U133A	EPHA2 TBC1D5 ARHGAP44 N4BP1 SH2B1	4.10e-04	195	73	5	6224_UP
Drug	Trihexyphenidyl-D,L Hydrochloride [58947-95-8]; Down 200; 11.8uM; HL60; HT_HG-U133A	PER3 POM121L2 ZC3H7B AGRN MBNL3	4.20e-04	196	73	5	2158_DN
Drug	fluphenazine dihydrochloride; Down 200; 10uM; MCF7; HT_HG-U133A	XYLT2 PER3 ZC3H7B NOTCH2 WWC1	4.20e-04	196	73	5	6954_DN
Drug	Gemfibrozil [25812-30-0]; Down 200; 16uM; PC3; HT_HG-U133A	PER3 NFATC1 KATNIP ZC3H7B PLXNB1	4.20e-04	196	73	5	5069_DN
Drug	Methylergometrine maleate [113-42-8]; Down 200; 8.8uM; MCF7; HT_HG-U133A	EPHA2 PER1 N4BP1 ZC3H7B MBNL3	4.20e-04	196	73	5	3222_DN
Drug	Timolol maleate salt [26921-17-5]; Down 200; 9.2uM; MCF7; HT_HG-U133A	TBC1D5 POU2F2 ARHGEF17 SH2B1 MBNL3	4.20e-04	196	73	5	5280_DN
Drug	Hymecromone [90-33-5]; Up 200; 22.8uM; MCF7; HT_HG-U133A	HIVEP3 BAZ2A POU2F2 ADAMTSL3 PLXNB1	4.20e-04	196	73	5	3383_UP
Drug	Epicatechin-(-) [154-23-4]; Down 200; 13.8uM; PC3; HT_HG-U133A	MAST4 BAZ2A KATNIP ZC3H7B NOTCH2	4.20e-04	196	73	5	4594_DN
Drug	5279552; Down 200; 22uM; MCF7; HT_HG-U133A_EA	BAZ2A KIAA0586 BCL6 ZC3H7B PLXNB1	4.20e-04	196	73	5	960_DN
Drug	Bupivacaine hydrochloride [18010-40-7]; Up 200; 12.4uM; PC3; HT_HG-U133A	MAST4 SERGEF BCL6 ZC3H7B NOTCH2	4.20e-04	196	73	5	5112_UP
Drug	Metoclopramide monohydrochloride [7232-21-5]; Up 200; 11.8uM; MCF7; HT_HG-U133A	HIVEP3 BAZ2A PER1 POM121L2 BCL6	4.20e-04	196	73	5	4750_UP
Drug	Naloxone hydrochloride [357-08-4]; Down 200; 11uM; PC3; HT_HG-U133A	NID2 TBC1D5 ZC3H7B NOTCH2 RBM38	4.20e-04	196	73	5	4645_DN
Drug	Dropropizine (R,S) [17692-31-8]; Down 200; 17uM; MCF7; HT_HG-U133A	MAST4 KIAA0586 ZC3H7B AGRN PLXNB1	4.20e-04	196	73	5	7429_DN
Drug	Epivincamine [6835-99-0]; Down 200; 11.2uM; PC3; HT_HG-U133A	PER3 TBC1D5 MUC5B BCL6 PLXNB1	4.20e-04	196	73	5	4500_DN
Drug	Calycanthine [595-05-1]; Down 200; 11.6uM; MCF7; HT_HG-U133A	MAST4 EPHA2 TBC1D5 ZC3H7B AGRN	4.20e-04	196	73	5	2764_DN
Drug	N6-methyladenosine [1867-73-8]; Down 200; 14.2uM; PC3; HT_HG-U133A	MAST4 PER1 ZC3H7B PLXNB1 NOTCH2	4.30e-04	197	73	5	6732_DN
Drug	AH6809; Up 200; 1uM; PC3; HT_HG-U133A	XYLT2 NID2 BAZ2A PER1 N4BP1	4.30e-04	197	73	5	7049_UP
Drug	Gly-His-Lys acetate salt; Down 200; 1uM; PC3; HT_HG-U133A	XYLT2 MAST4 BAZ2A NOTCH2 WWC1	4.30e-04	197	73	5	6570_DN
Drug	Amyleine hydrochloride [532-59-2]; Up 200; 14.8uM; PC3; HG-U133A	XYLT2 HIVEP3 BAZ2A KMT2A POM121L2	4.30e-04	197	73	5	1909_UP
Drug	Pirenzepine dihydrochloride [29868-97-1]; Down 200; 9.4uM; HL60; HG-U133A	DAZAP1 PER1 KATNIP N4BP1 ZC3H7B	4.30e-04	197	73	5	1388_DN
Drug	Mimosine [500-44-7]; Up 200; 20.2uM; PC3; HT_HG-U133A	KMT2D ETV1 KMT2A MBNL3 NOTCH2	4.30e-04	197	73	5	6703_UP
Drug	Flecainide acetate [54143-56-5]; Down 200; 8.4uM; MCF7; HT_HG-U133A	XYLT2 MAST4 N4BP1 ZC3H7B SH2B1	4.30e-04	197	73	5	3937_DN
Drug	clozapine; Down 200; 10uM; HL60; HT_HG-U133A	NFATC1 PER1 SH2B1 NOTCH2 WWC1	4.30e-04	197	73	5	2689_DN
Drug	Acyclovir [59277-89-3]; Down 200; 17.8uM; MCF7; HT_HG-U133A	BAZ2A EPHA2 POM121L2 POU2F2 SH2B1	4.30e-04	197	73	5	5643_DN
Drug	Triamterene [396-01-0]; Down 200; 15.8uM; MCF7; HT_HG-U133A	XYLT2 EPHA2 ZC3H7B AGRN WWC1	4.30e-04	197	73	5	1697_DN
Drug	Dihydroergotamine tartrate [5989-77-5]; Up 200; 3uM; MCF7; HT_HG-U133A	HIVEP3 BAZ2A SERGEF PER1 INPP5J	4.30e-04	197	73	5	6840_UP
Drug	alpha-Santonin [481-06-1]; Down 200; 16.2uM; MCF7; HT_HG-U133A	SERGEF ARHGEF17 SH2B1 INPP5J PLXNB1	4.30e-04	197	73	5	3877_DN
Drug	Fenbufen [36330-85-5]; Up 200; 15.8uM; MCF7; HT_HG-U133A	HIVEP3 KMT2D BAZ2A MUC5B ZC3H7B	4.30e-04	197	73	5	2308_UP
Drug	Diazoxide [364-98-7]; Down 200; 17.4uM; PC3; HT_HG-U133A	BAZ2A TBC1D5 N4BP1 SH2B1 WWC1	4.30e-04	197	73	5	2052_DN
Drug	Praziquantel [55268-74-1]; Down 200; 12.8uM; PC3; HT_HG-U133A	MAST4 NFATC1 BAZ2A AGRN WWC1	4.30e-04	197	73	5	5874_DN
Drug	Picotamide monohydrate [80530-63-8]; Down 200; 10.2uM; PC3; HT_HG-U133A	MAST4 NFATC1 FA2H N4BP1 NOTCH2	4.30e-04	197	73	5	2070_DN
Drug	Pseudopelletierine hydrochloride [6164-62-1]; Up 200; 21uM; MCF7; HT_HG-U133A	BAZ2A ARHGEF17 SH2B1 INPP5J RBM38	4.30e-04	197	73	5	2766_UP
Drug	Isometheptene mucate; Up 200; 8.2uM; PC3; HT_HG-U133A	HIVEP3 BAZ2A BCL6 MBNL3 NOTCH2	4.30e-04	197	73	5	5082_UP
Drug	AC1L1C2F	TPSAB1 NID2 TPSB2 NOTCH2	4.34e-04	110	73	4	CID000001711
Drug	Budesonide [51333-22-3]; Down 200; 9.2uM; MCF7; HT_HG-U133A	MAST4 PER3 N4BP1 ANKRD12 ARHGEF17	4.40e-04	198	73	5	5431_DN
Drug	Metoclopramide monohydrochloride [7232-21-5]; Down 200; 11.8uM; MCF7; HT_HG-U133A	PER3 SERGEF KMT2A ZC3H7B ARHGEF17	4.40e-04	198	73	5	4750_DN
Drug	Trapidil [15421-84-8]; Up 200; 19.4uM; HL60; HT_HG-U133A	PER1 ETV1 ZC3H7B MBNL3 WWC1	4.40e-04	198	73	5	3136_UP
Drug	(-)-Adenosine 3',5'-cyclic monophosphate [60-92-4]; Down 200; 12.2uM; HL60; HT_HG-U133A	HIVEP3 NFATC1 MAP3K11 KMT2A SH2B1	4.40e-04	198	73	5	2969_DN
Drug	CP-944629 [668990-94-1]; Up 200; 10uM; PC3; HT_HG-U133A	MAST4 PER1 N4BP1 ZC3H7B AGRN	4.40e-04	198	73	5	7549_UP
Drug	Proparacaine hydrochloride [5875-06-9]; Down 200; 12uM; PC3; HT_HG-U133A	HIVEP3 DENND4B AGRN NOTCH2 RBM38	4.40e-04	198	73	5	6332_DN
Drug	Oxytetracycline dihydrate [6153-64-6]; Down 200; 8uM; MCF7; HT_HG-U133A	MAST4 EPHA2 TOLLIP ZC3H7B NOTCH2	4.40e-04	198	73	5	3170_DN
Drug	Minoxidil [38304-91-5]; Down 200; 19.2uM; MCF7; HT_HG-U133A	HIVEP3 BAZ2A FA2H SH2B1 PLXNB1	4.40e-04	198	73	5	4800_DN
Drug	Gelsemine [509-15-9]; Down 200; 12.4uM; HL60; HT_HG-U133A	BAZ2A N4BP1 ZC3H7B AGRN NOTCH2	4.40e-04	198	73	5	2162_DN
Drug	Bisoprolol fumarate; Down 200; 9uM; HL60; HT_HG-U133A	BAZ2A KMT2A KATNIP ZC3H7B RBM38	4.40e-04	198	73	5	1287_DN
Drug	Vitexin [3681-93-4]; Down 200; 9.2uM; HL60; HT_HG-U133A	HIVEP3 PER1 ETV1 POM121L2 AGRN	4.40e-04	198	73	5	2155_DN
Drug	Tiabendazole [148-79-8]; Down 200; 19.8uM; PC3; HT_HG-U133A	MAMLD1 PER1 ETV1 N4BP1 ZC3H7B	4.40e-04	198	73	5	4579_DN
Disease	Colorectal Carcinoma	TBX22 HIVEP3 NFATC1 NPAP1 PER1 ETV1 GATA5 FOXH1 ADAMTSL3	8.85e-05	702	77	9	C0009402
Disease	body weight	TBX22 ADAMTS10 NID2 MAST4 EPHA6 E2F7 POM121L2 BCL6 ADAMTSL3 POM121C DENND1A SH2B1	9.91e-05	1261	77	12	EFO_0004338
Disease	triacylglycerol 58:6 measurement	HIVEP3 TENM2	1.86e-04	8	77	2	EFO_0010440
Disease	tryptase beta-2 measurement	TPSAB1 TPSB2	2.39e-04	9	77	2	EFO_0008306
Disease	ventricular septal defect (is_implicated_in)	NFATC1 GATA5	5.99e-04	14	77	2	DOID:1657 (is_implicated_in)
Disease	Gastro-enteropancreatic neuroendocrine tumor	POU2F2 NOTCH2	6.90e-04	15	77	2	C2930967
Disease	T-Cell Lymphoma	KMT2D BCL6	7.88e-04	16	77	2	C0079772
Disease	Seasonal Affective Disorder	OPN4 PER3	7.88e-04	16	77	2	C0085159
Disease	Tetralogy of Fallot	GATA5 FOXH1	7.88e-04	16	77	2	C0039685
Disease	comparative body size at age 10, self-reported	ADAMTS10 MAST4 NFATC1 ZC3H7B ADAMTSL3 SH2B1	8.12e-04	420	77	6	EFO_0009819
Disease	Lymphoma, Follicular	KMT2D BCL6	1.24e-03	20	77	2	C0024301
Disease	urticaria	TPSAB1 TPSB2	1.24e-03	20	77	2	EFO_0005531
Disease	Joubert syndrome 1	KIAA0586 KATNIP	1.37e-03	21	77	2	C4551568
Disease	alcohol consumption measurement	MAST4 SERGEF CLDN25 POU2F2 ZC3H7B DENND1A AGRN TENM2 SH2B1 WWC1	1.42e-03	1242	77	10	EFO_0007878
Disease	feeling nervous measurement	ZC3H7B DENND1A ATF6B	1.55e-03	87	77	3	EFO_0009597
Disease	eosinophil count	HIVEP3 NEU4 FA2H TBC1D5 MAP3K11 POU2F2 N4BP1 BCL6 ZC3H7B ATF6B NOTCH2	1.62e-03	1488	77	11	EFO_0004842
Disease	sensory peripheral neuropathy, remission	ETV1 KMT2A	1.64e-03	23	77	2	EFO_0009785, MONDO_0002321
Disease	neuroimaging measurement	MAST4 TBC1D5 DENND4B MAP3K11 POM121C DENND1A SH3RF3 WNK2 WWC1	1.84e-03	1069	77	9	EFO_0004346
Disease	Neurodevelopmental Disorders	HIVEP3 KMT2A PLXNB1	1.87e-03	93	77	3	C1535926
Disease	obesity (implicated_via_orthology)	TBC1D5 ETV1 PLXNB1 NOTCH2	2.45e-03	215	77	4	DOID:9970 (implicated_via_orthology)
Disease	Myeloid Leukemia, Chronic	PER3 PER1	2.61e-03	29	77	2	C0023473

Protein segments in the cluster

Peptide	Gene	Start	Entry
AQPVPFMCNAPASPI	nan	21	Q8N814
ISAQMPCNAAPTPPP	BAZ2A	1326	Q9UIF9
FTPVPPTPPDACRGM	AGRN	161	O00468
FPLMAGPTVPLSCAP	CLDN25	196	C9JDP6
DPASFMPPQQPCSFP	ANKRD12	1481	Q6UB98
LAFPPPPSQAAPDMS	DAZAP1	321	Q96EP5
PPAHCSPAAKPPATM	ADAMTS10	981	Q9H324
CVPAPMAPPHTRGFP	MUC5B	5741	Q9HC84
MLLQPAPCAPSAGFP	RBM38	1	Q9H0Z9
APVPVDMPCLPLAAP	ARHGEF17	1021	Q96PE2
STCPPAVAGPLPTMY	NOTCH2	2326	Q04721
TPNVVMPLAPPPTSC	FOXH1	286	O75593
SSPSPPCSPLMADPL	WWC1	541	Q8IX03
MPSAPATSPPVKCPP	KATNIP	711	O60303
FEPPMPPPCQSPASL	C9orf131	336	Q5VYM1
PPAAFPAPLVTPMVA	PER1	906	O15534
TFMTVFLPDPPVCPL	PER3	846	P56645
VMCPSPDPSEAPVLP	PLXNB1	586	O43157
SEPCNSFPPLPTMPR	ETV1	191	P50549
ACPSSPFPPAMPRVL	GHDC	501	Q8N2G8
MPPDPSSCLVAGFPP	NFATC1	736	O95644
AGFPPCPQRSTLMPA	NFATC1	746	O95644
NPCSAAPMLPSPGKP	POU2F2	356	P09086
TLALPMPFAAPPQSP	NEU4	361	Q8WWR8
MKPSAAPSPSPALPF	NUTM1	16	Q86Y26
MQTPPSLPPCPESAG	POM121C	581	A8CG34
SMGPPASVPLPAPFF	POM121B	361	A6NF01
TPACIPTVAPPMVRP	NID2	1081	Q14112
PSPTQEPSCMATPAP	OPN4	11	Q9UHM6
PAAPAASSAPPMFKP	POM121	716	Q96HA1
AAPAAAPTPAPPSMI	POM121	1001	Q96HA1
MAPAPPPAASFSPSE	FA2H	1	Q7L5A8
SMDSPVPLYPTDCPP	FAM189B	271	P81408
PSLASPVCPGPSMAP	GATA5	331	Q9BWX5
APPLSGPMAPCQSAL	HDAC10	326	Q969S8
FSVPCMVLPSPPLGP	E2F7	741	Q96AV8
MSLPSPSPSRELCPP	GAB4	1	Q2WGN9
APQDPASMPCTRPPS	EPHA2	316	P29317
RAYTAPPACQPPMEP	BCL6	406	P41182
PPPPFSPQSLMVSCM	MAMLD1	356	Q13495
QPAFIPAGPILCMAP	MBNL3	301	Q9NUK0
LSPPPMPFRKCSNPD	MAST4	126	O15021
LNPFVPSMPAAPPTL	DENND1A	831	Q8TEH3
AFPLPESVPVFCLPM	DENND4B	226	O75064
MPPTIPLASPFLPAS	KMT2A	586	Q03164
VLCFSPPSMPAPAPA	C4orf54	1576	D6RIA3
ISPPWFMACSPPPLS	FAM53C	326	Q9NYF3
LPIPSTCPEPFAQLM	MAP3K11	341	Q16584
KDPPSMACTRPPSAP	EPHA6	321	Q9UF33
SPGPCPATSPRPMTL	SH2B1	376	Q9NRF2
LPCSRPPNSMPSSPH	SERGEF	316	Q9UGK8
TLPPASETFPPGMPC	TPSAB1	141	Q15661
TLPPASETFPPGMPC	TPSB2	141	P20231
LSASGPLAVPPMCPV	SLC25A47	136	Q6Q0C1
PSSHNPPPVSCQMPL	TENM2	186	Q9NT68
PISMCVDSPPPLSFL	NPAP1	516	Q9NZP6
VSCAPPSMQPPAPPA	ARHGAP44	536	Q17R89
VALPTPMPTPAQPAF	POM121L2	806	Q96KW2
SIVPAPMPGNSCPPE	ATF6B	306	Q99941
PNRSPCVPPAPDMAL	INPP5J	356	Q15735
QPAPTCAEPPPAMGS	PRR22	31	Q8IZ63
MDPAVNPAFPPAAPA	ZFR2	41	Q9UPR6
PVPASAPSPAPALVM	SPEM3	396	A0A1B0GUW6
PPVQMCPRPAIPLTS	SH3RF3	656	Q8TEJ3
PTSSLGMPCPEAYLP	TBX22	351	Q9Y458
PAVCSPGMVPVALPP	TOLLIP	206	Q9H0E2
PSSPSTPPCEMLGPV	SEPTIN12	16	Q8IYM1
SAPPLALPACPDTMV	HIVEP3	1301	Q5T1R4
TGPTIFSPFCSMPPL	ZGRF1	146	Q86YA3
FSPFCSMPPLFPTVG	ZGRF1	151	Q86YA3
FEMPCLPAIPSVPNT	PLEKHG2	666	Q9H7P9
PVCSPLVFSDPLMGP	TBC1D5	751	Q92609
MLVLPSPCPQPLAFS	ZNF581	1	Q9P0T4
DPAMSFAPVLPPPST	WNK2	701	Q9Y3S1
LVAHPPCPSPAASMP	TIGD5	356	Q53EQ6
SGLPAPQFAIRMCPP	WDR11	461	Q9BZH6
TAAPPMGTPLCRFEP	XYLT2	571	Q9H1B5
VPFMPFPAGTKAPSP	KIAA0586	1186	Q9BVV6
CSPYTPPPMLSPIRE	ZNF541	991	Q9H0D2
SGAQKPAPSPEPCMP	ZC3H7B	391	Q9UGR2
PAPSPEPCMPNTALL	ZC3H7B	396	Q9UGR2
PPAMSQACNTEPCPP	ADAMTSL3	691	P82987
PASPILMEPLPPQCS	KMT2D	1011	O14686
SPMGDLSCPAPSPAP	KMT2D	1096	O14686
PNCSTLSPPMPLPQL	N4BP1	556	O75113