Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

OR52L2P OR10H4 IL21R TNFRSF1A NCR2 OR56A1 OR52N5

1.58e-041353197GO:0004888
GeneOntologyMolecularFunctionolfactory receptor activity

OR52L2P OR10H4 OR56A1 OR52N5

6.41e-04431194GO:0004984
MousePhenodecreased ceramide level

CYP4F22 NIPAL4

3.37e-064112MP:0020583
MousePhenoimpaired skin barrier function

CYP4F22 NIPAL4 TNFRSF1A

1.47e-0564113MP:0002796
MousePhenoincreased susceptibility to experimental autoimmune encephalomyelitis

BTLA IL21R TNFRSF1A

1.77e-0568113MP:0004799
MousePhenoabnormal epidermal lamellar body morphology

CYP4F22 NIPAL4

4.37e-0513112MP:0009608
MousePhenoabnormal corneocyte morphology

CYP4F22 NIPAL4

8.55e-0518112MP:0030605
MousePhenodecreased urine potassium level

ADCY6 CLN3

9.56e-0519112MP:0005618
MousePhenoshiny skin

CYP4F22 NIPAL4

1.54e-0424112MP:0001196
MousePhenoincreased susceptibility to autoimmune disorder

BTLA IL21R TNFRSF1A

2.07e-04155113MP:0005350
MousePhenoabnormal ceramide level

CYP4F22 NIPAL4

2.76e-0432112MP:0012232
MousePhenogranulomatous inflammation

IL21R TNFRSF1A

3.50e-0436112MP:0002500
MousePhenoabnormal urine potassium level

ADCY6 CLN3

3.50e-0436112MP:0004820
MousePhenoabnormal sphingolipid level

CYP4F22 NIPAL4

4.32e-0440112MP:0012230
MousePhenoabnormal IgG1 level

BTLA IL21R TNFRSF1A

4.37e-04200113MP:0020175
MousePhenodecreased susceptibility to autoimmune diabetes

IL21R TNFRSF1A

5.47e-0445112MP:0004804
MousePhenodecreased urine osmolality

ADCY6 CLN3

7.88e-0454112MP:0002988
MousePhenoabnormal urine osmolality

ADCY6 CLN3

1.14e-0365112MP:0002987
MousePhenoabnormal skin physiology

CYP4F22 NIPAL4 TNFRSF1A

1.26e-03288113MP:0005501
MousePhenoabnormal epidermis stratum granulosum morphology

CYP4F22 NIPAL4

1.32e-0370112MP:0001239
MousePhenoabnormal susceptibility to autoimmune disorder

BTLA IL21R TNFRSF1A

1.52e-03307113MP:0002425
MousePhenochronic inflammation

IL21R TNFRSF1A

1.68e-0379112MP:0002499
Domain-

SIRPD BTLA IL21R NCR2

3.24e-036631842.60.40.10
DomainIg-like_fold

SIRPD BTLA IL21R NCR2

4.06e-03706184IPR013783
DomainOlfact_rcpt

OR10H4 OR56A1 OR52N5

5.96e-03393183IPR000725
DomainIg_sub

SIRPD BTLA NCR2

7.21e-03421183IPR003599
DomainIG

SIRPD BTLA NCR2

7.21e-03421183SM00409
DomainIG_LIKE

SIRPD BTLA NCR2

1.10e-02491183PS50835
DomainIg-like_dom

SIRPD BTLA NCR2

1.17e-02503183IPR007110
DomainV-set

SIRPD NCR2

1.33e-02184182PF07686
DomainIg_V-set

SIRPD NCR2

1.54e-02199182IPR013106
DomainGPCR_Rhodpsn_7TM

OR10H4 OR56A1 OR52N5

2.51e-02670183IPR017452
Domain7tm_1

OR10H4 OR56A1 OR52N5

2.58e-02677183PF00001
DomainG_PROTEIN_RECEP_F1_1

OR10H4 OR56A1 OR52N5

2.66e-02685183PS00237
DomainG_PROTEIN_RECEP_F1_2

OR10H4 OR56A1 OR52N5

2.72e-02691183PS50262
DomainGPCR_Rhodpsn

OR10H4 OR56A1 OR52N5

2.73e-02692183IPR000276
Pubmed

Pretreatment Levels of Soluble Tumor Necrosis Factor Receptor 1 and Hepatocyte Growth Factor Predict Toxicity and Overall Survival After 90Y Radioembolization: Potential Novel Application of Biomarkers for Personalized Management of Hepatotoxicity.

HGF TNFRSF1A

2.83e-07219234503962
Pubmed

HGF Secreted by Menstrual Blood-Derived Endometrial Stem Cells Ameliorates Non-Alcoholic Fatty Liver Disease Through Downregulation of Hepatic Rnf186.

HGF RNF186

2.83e-07219236573461
Pubmed

B and T lymphocyte attenuator suppresses IL-21 production from follicular Th cells and subsequent humoral immune responses.

BTLA IL21R

8.48e-07319220660710
Pubmed

MEK, p38, and PI-3K mediate cross talk between EGFR and TNFR in enhancing hepatocyte growth factor production from human mesenchymal stem cells.

HGF TNFRSF1A

4.24e-06619219692652
Pubmed

GVHD prevents NK-cell-dependent leukemia and virus-specific innate immunity.

IL21R TNFRSF1A

7.90e-06819227927647
Pubmed

Autosomal Recessive Congenital Ichthyosis

CYP4F22 NIPAL4

2.20e-051319220301593
Pubmed

TNF-α sculpts a maturation process in vivo by pruning tolerogenic dendritic cells.

BTLA TNFRSF1A

2.20e-051319235417681
Pubmed

The human olfactory receptor gene family.

OR52L2P OR10H4 OR56A1 OR52N5

1.86e-0454119414983052
Pubmed

Network-Based Combinatorial CRISPR-Cas9 Screens Identify Synergistic Modules in Human Cells.

IL21R TNFRSF1A

5.41e-046319230762338
Cytoband11p15.4

OR52L2P OR56A1 OR52N5

7.50e-0520019311p15.4
Cytoband19p13.12

CYP4F22 OR10H4

1.96e-045019219p13.12
CytobandEnsembl 112 genes in cytogenetic band chr11p15

OR52L2P OR56A1 OR52N5

1.54e-03564193chr11p15
CytobandEnsembl 112 genes in cytogenetic band chr16p12

CLN3 IL21R

2.29e-03172192chr16p12
GeneFamilyADAM metallopeptidase domain containing|CD molecules

BTLA IL21R TNFRSF1A NCR2

1.87e-04394144471
GeneFamilyOlfactory receptors, family 52

OR52L2P OR52N5

6.41e-0449142165
GeneFamilyAdenosine receptors|V-set domain containing

SIRPD NCR2

6.85e-03163142590
CoexpressionBALLIF_DEVELOPMENTAL_DISABILITY_P16_P12_DELETION

CLN3 IL21R

3.08e-0513172M14238
ToppCellStriatum-Macroglia-POLYDENDROCYTE-P1-P1_1-Trf|Striatum / BrainAtlas - Mouse McCarroll V32

NIPAL4 BTLA

4.57e-0479182a60fcbb278ba629af922c53faf58e4d96c537b15
ToppCellStriatum-Macroglia-POLYDENDROCYTE-P1-P1_1-Trf-Oligodendrocyte.Trf.Ctps_(Ctps)|Striatum / BrainAtlas - Mouse McCarroll V32

NIPAL4 BTLA

4.57e-0479182239d34f40c3a96186231f3aabd41c4988af3f372
ToppCellP07-Hematopoietic|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

BTLA IL21R

1.38e-03138182fb8038393c2b88eb29bd23574c0c6178644900be
ToppCell10x3'2.3-week_12-13-Myeloid_DC-DC-DC2|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

BTLA NCR2

1.42e-03140182c3331cb7720f93af8bab35d02c6cbe87dd324d91
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L5_PT-L5_PT_VISp_Krt80|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

HGF LUZP2

1.44e-0314118240ef6d792e11fe10963d64eb0b606b90556c1a70
ToppCellTCGA-Bladder|World / Sample_Type by Project: Shred V9

CYP4F22 NIPAL4

1.46e-0314218258d1fdc5ec4e5bf307b7a502c081a8a84d7560cd
ToppCellP07-Hematopoietic-Immune-immune_cell_unspecified|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

BTLA IL21R

1.51e-03144182eb057dbdb2a5a2d29b93e5ed5479a3fd1bf3fd26
ToppCellfacs-MAT-Fat-18m-Epithelial-epithelial_cell|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM86B RNF186

1.51e-03144182fd852095dcd716ac53b0fd25d83e6f454b2ae794
ToppCellfacs-MAT-Fat-18m-Epithelial-nan|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM86B RNF186

1.51e-0314418265ffd8a1620b178d995fe8c913871f0b376b896f
ToppCellP07-Hematopoietic-Immune|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

BTLA IL21R

1.51e-03144182962698c5c15bd583fccda0593b7aab5f2eb4bc9f
ToppCellfacs-MAT-Fat-18m-Epithelial|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM86B RNF186

1.51e-03144182e4e148007c772cd163a34fb172e05184f7352a2b
ToppCellLymphoid-B_cells|World / shred on cell class and cell subclass (v4)

BTLA IL21R

1.57e-03147182aa4486200c523f2c9d3bad7a14f1764c2d92076b
ToppCellPND01-Immune-Immune_Lymphocytic_T/NK|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

BTLA IL21R

1.59e-03148182b78dac56b333bf901136ccafb0999f345e978f51
ToppCellCOVID-19-kidney-Technical/muscle_(Imm)|COVID-19 / Disease (COVID-19 only), tissue and cell type

CYP4F22 LUZP2

1.63e-031501820205318a870e091add66ee4305747dda9f51510d
ToppCellP15-Hematopoietic-Immune|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

BTLA IL21R

1.65e-03151182a54045cac65a66197e3ad2b002fa6c511102834a
ToppCellPND01-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

BTLA IL21R

1.65e-03151182ee56b88c56c3b6a5ec9644c43cae521ea0e05920
ToppCellPND01-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

BTLA IL21R

1.65e-031511822c239b09970acbaa90c5ebe1097f453c516f868e
ToppCellP15-Hematopoietic-Immune-immune_cell_unspecified|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

BTLA IL21R

1.65e-031511826b905d309f2a9b8828399b36f4942aec8696bee6
ToppCellChildren_(3_yrs)-Mesenchymal-myofibroblast_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

NIPAL4 LUZP2

1.67e-03152182621e9b33cd3bb1c7b7d0633069f286b203e3d9c0
ToppCellPND01-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B-B_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

BTLA IL21R

1.67e-03152182b750302d442160a1007659c2386ac90282bf95d2
ToppCellfrontal_cortex|World / Per Region, Lineage, Cell class, Cell type, Cell subtype

HGF LUZP2

1.67e-03152182f9c29d4568402ca07a717dbffb3ccc7f35c5fe56
ToppCellP28-Hematopoietic|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

BTLA IL21R

1.72e-0315418213980ae1957b05350c11171c9c118decfe998d3d
ToppCell10x5'-blood-Lymphocytic_T_CD8-Trm_gut_CD8|blood / Manually curated celltypes from each tissue

CYP4F22 BTLA

1.72e-03154182c77a02df403358361aca86c679d5c43a64ff2f7f
ToppCellfacs-Large_Intestine-Distal-3m-Epithelial-Lgr5-_amplifying_undifferentiated_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BTLA IL21R

1.74e-03155182f3489a548a2c0cc2d9117ff85865c6089ea0835d
ToppCellfacs-Large_Intestine-Distal-3m-Epithelial-epithelial_cell_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BTLA IL21R

1.74e-031551820e24e767a3895d31d34cabeaca0354aadae34e44
ToppCellfacs-Spleen-nan-3m-Myeloid-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HGF TNFRSF1A

1.76e-03156182da4f35353a84d919e683554932f110e29568df33
ToppCellfacs-Spleen-nan-3m-Myeloid-granulocyte|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HGF TNFRSF1A

1.76e-03156182f1e25ff85c5f2f8555f9fb5ae5daed7ddb418fd1
ToppCellfacs-Spleen-nan-3m-Myeloid|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HGF TNFRSF1A

1.76e-03156182f532ef4e92ac7661b1a8a4f2e98d80ce8d4e3655
ToppCellP28-Hematopoietic-Immune-immune_cell_unspecified|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

BTLA IL21R

1.78e-03157182a70f93aff07b6b7a9efce33b12b024116648dc0a
ToppCellAdult-Immune-mast_cell-D231|Adult / Lineage, Cell type, age group and donor

CYP4F22 BTLA

1.78e-031571824c63bb91f8708644e6ce2500072a4eeb8e1079dd
ToppCellP28-Hematopoietic-Immune|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

BTLA IL21R

1.78e-03157182b1f520b1e0ea7abb19d0dd27021eafbea0fd90cd
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c02-NCAM1|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

ADCY6 TNFRSF1A

1.81e-031581824d997efc36fd8946775fe74dd9ac9ccd5ade64ff
ToppCellControl-Myeloid-DC_Langerhans|Myeloid / Disease state, Lineage and Cell class

OR10H4 IL21R

1.85e-03160182174775fb5cc7b478c6cd04f7c565738648ec2fc3
ToppCellPND07-Immune-Immune_Myeloid-DC-maDC-maDC_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADCY6 IL21R

1.85e-0316018201f22cdb2a2f73776b7f91746e95c1850df94235
ToppCellfacs-Marrow-Granulocytes-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM86B ADCY6

1.85e-0316018256e6f4b82b5dc41c45f9d253c2db314a6f702b84
ToppCellfacs-Marrow-Granulocytes-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM86B ADCY6

1.85e-03160182bb1b966fb9e801db15e67d03e49db4609d6f935a
ToppCellPND07-Immune-Immune_Myeloid-DC-maDC|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADCY6 IL21R

1.85e-031601827db30647b596f0c419087e6fabb9b99dcd5bddd4
ToppCellPND03-Immune-Immune_Myeloid-DC-cDC1-cDC1_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TMEM86B BTLA

1.88e-031611825cb91ae9674b370a27be0d5852c3816b4434239e
ToppCellPND03-Immune-Immune_Myeloid-DC-cDC1|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TMEM86B BTLA

1.88e-031611820e2b54a63781397f6b99eb0e201fbb820cbd7cc6
ToppCellIPF-Epithelial-Ionocyte|World / Disease state, Lineage and Cell class

RNF186 OR56A1

1.88e-03161182f1cd5c938cdc08ad8995371b72493850a6cf277a
ToppCellfacs-Marrow-Granulocytes-18m-Hematologic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM86B ADCY6

1.88e-0316118260f433eab9d5531bdf6aa86b0265f20b866b904c
ToppCellE18.5-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B-B_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

BTLA IL21R

1.90e-0316218259f6a9005c4f22f084c25ea36f3cacce5144a9ae
ToppCellCOVID-19-kidney-Technical/muscle_(Imm)|kidney / Disease (COVID-19 only), tissue and cell type

CYP4F22 LUZP2

1.92e-0316318219c28ce16a588a7f4a035c32726f6ccd67702b5b
ToppCellHealthy_Control-Lymphoid-B-|Healthy_Control / Condition, Lineage, Cell class and cell subclass

NIPAL4 BTLA

1.92e-03163182d84bd41b4494c7d5c7f88d511bfe481fb12f079d
ToppCellHealthy_Control-Lymphoid-B|Healthy_Control / Condition, Lineage, Cell class and cell subclass

NIPAL4 BTLA

1.92e-031631820f723ec2503afa1b3ebb0754972438ffb6e6179d
ToppCellImmune_cells-B_cell|World / Lineage and Cell class

BTLA IL21R

1.92e-031631823a02465de7c2f7cea227e289fb082a1fb6400301
ToppCellfacs-Limb_Muscle-forelimb_and_hindlimb-18m-Lymphocytic-B_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLN3 IL21R

1.94e-03164182875d922eec7e3df0998ddf0c8c4dee2dcd5b23ca
ToppCellfacs-Limb_Muscle-forelimb_and_hindlimb-18m-Lymphocytic|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLN3 IL21R

1.94e-031641828bcfc93220d7c99dddb32b7fa7fb9aec2a1c63fa
ToppCellfacs-Limb_Muscle-forelimb_and_hindlimb-18m-Lymphocytic-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLN3 IL21R

1.94e-03164182b175258fb0885afd84d4a414c0ae441f880e8469
ToppCelldroplet-Lung-30m-Hematologic-myeloid-myeloid_dendritic_cell-myeloid_dendritic_type_1|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

BTLA IL21R

1.97e-03165182479962ce1c3d6636ae62b6709635299748653801
ToppCellmild_COVID-19_(asymptomatic)-Plasmablast|World / disease group, cell group and cell class (v2)

NIPAL4 BTLA

2.02e-03167182f26ae4de4804a3486502e3df37eabf3dfca688f5
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Lymphocytic|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BTLA IL21R

2.04e-03168182dc1143bd8db70c490167d73a525fd9b783eba960
ToppCell356C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-2|356C / Donor, Lineage, Cell class and subclass (all cells)

CYP4F22 BTLA

2.04e-031681829d6ca10c272aea28082c09d469940f7232f6461c
ToppCellP28-Epithelial-epithelial_progenitor_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

LUZP2 RNF186

2.04e-0316818203c95ad3684caec7a6d581006b237cc5fa230685
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Lymphocytic-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BTLA IL21R

2.04e-03168182a75d63ae8ad64b5560853775f6df398feb314ce8
ToppCellASK440-Immune-B_cell|Immune / Donor, Lineage and Cell class of Lung cells from Dropseq

ADCY6 BTLA

2.04e-03168182127559d1a083c68cda9fce143afcc3eec168df17
ToppCell3'-Child04-06-SmallIntestine-Epithelial-mature_enterocytic-Paneth|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RNF186 OR52N5

2.04e-031681823e3f611e9bbec8224264666be14a4e7db343070e
ToppCelldroplet-Lung-LUNG-30m-Myeloid-Myeloid_Dendritic_Type_1|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BTLA IL21R

2.04e-031681822c996d09b6a8ccd3c708146eca310b02eafff425
ToppCellBasal_cells-IPF_03|World / lung cells shred on cell class, cell subclass, sample id

NIPAL4 NCR2

2.04e-0316818248089fa2d4a0f31a72405717119b767a92571f01
ToppCellPND10-Immune-Immune_Myeloid-DC-maDC-maDC_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADCY6 IL21R

2.06e-03169182a83e4078db91ecedee637b28b12ec38640fe45f9
ToppCellPND10-Immune-Immune_Myeloid-DC-maDC|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADCY6 IL21R

2.06e-03169182f914aa8899fa170a09da31e5fad86de897ea789b
ToppCelldroplet-Liver-HEPATOCYTES-1m-Lymphocytic|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BTLA IL21R

2.06e-03169182d721dbb317a88113b4f76688111908d00f23e899
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L6_LHX6_GLP1R|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

HGF IL21R

2.09e-0317018240675b55269ffa57fb7fcdb903c81b02b4e01f8f
ToppCellBAL-Mild-Lymphocyte-T/NK-CD4+_T-Treg-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

BTLA IL21R

2.09e-031701829a21048b0248a0cae00ec2d71d5056a678495385
ToppCellBAL-Mild-Lymphocyte-T/NK-CD4+_T-Treg|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

BTLA IL21R

2.09e-03170182aeac9de12efc727313946a77823aba8ab7cdfbfb
ToppCellMonocytes-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

CYP4F22 IL21R

2.09e-031701824e93b66b3033e6e4d5f6d2f41974623a53108f5e
ToppCellfacs-Lung-nan-3m-Lymphocytic-B_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BTLA IL21R

2.11e-0317118243d8fd9b9546e84a652564fe96b514b34b06262b
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic-Plasmacytoid_Dendritic_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NIPAL4 BTLA

2.11e-0317118239c8ae139e449217091e1481eb5e2aafb8f69a1c
ToppCellLPS-IL1RA-Lymphocytic_NKT-T_cells-T-cells|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

BTLA IL21R

2.11e-03171182539ea88acc6f948efdeae8b69e5c5ffaee29f1d9
ToppCellfacs-Lung-nan-3m-Lymphocytic-B_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BTLA IL21R

2.11e-03171182a31c23406cf6d6a17358a8fb41d392a7fb0306e0
ToppCelldroplet-Trachea-nan-3m-Myeloid-macrophage|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BTLA IL21R

2.14e-03172182f6c00a6a7e81aaf96c55eb3a3c88e3719f102ea0
ToppCellPND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

BTLA IL21R

2.14e-031721823784fd1e833703519889942e39fda991f03c3c76
ToppCellfacs-Heart-RV-18m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP4F22 IL21R

2.14e-03172182a26a73c41e5a05c9dd47a99f3320295f684c5e54
ToppCellfacs-Lung-18m-Hematologic-myeloid-myeloid_dendritic_cell-Ccr7+_dendritic|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ADCY6 IL21R

2.14e-0317218248d0cfc37d1b1ae48ed8f8b2711abeb609d2bb6e
ToppCellImmune_cells-B_cell|Immune_cells / Lineage and Cell class

BTLA IL21R

2.14e-03172182b646894b691a99bf2742bd9da8e578dff0e87f1f
ToppCellPND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

BTLA IL21R

2.14e-03172182995139aa38f8b9ff23166128b15476cd8a3ff1b8
ToppCellfacs-Lung-EPCAM-18m-Myeloid-dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADCY6 IL21R

2.14e-031721827c085c02b59e24e2a2cd393b5e692f9fb19257fe
ToppCelldroplet-Trachea-3m-Hematologic-myeloid-tracheal_macrophage|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

BTLA IL21R

2.14e-03172182f3bbe3f069ad070778430d1a6cd9db0a76deb8de
ToppCellPSB-critical-LOC-Lymphoid-B_cell|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

BTLA IL21R

2.14e-0317218257b91bcce3f122f3d3267cf4d3a3ef67842caa9a
ToppCellLPS-IL1RA-Lymphocytic_NKT-T_cells|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

BTLA IL21R

2.14e-031721820fc692be845d4225ff8b63bf9195724fc8510c2c
ToppCellfacs-Lung-EPCAM-18m-Myeloid-Ccr7+_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADCY6 IL21R

2.14e-03172182c5caae0b21e35a2d5dcd898fbfa1ef33f92c019f
ToppCelldroplet-Lung-nan-3m-Lymphocytic-B_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BTLA IL21R

2.16e-0317318225d72fa7a84baf5660ead6da67327590f5c91860
ToppCelldroplet-Kidney-KIDNEY-1m-Lymphocytic-nan|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BTLA IL21R

2.16e-03173182de124fb7ded04664d4184bf12f1f201c0784f07c
ToppCellfacs-Trachea-nan-24m-Myeloid-lymphocyte_of_B_lineage|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BTLA IL21R

2.16e-0317318271c90c57225e452c73bf7bea46b454c472bf5f76
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C_(NP)-Glut_NP_L5/6_FEZF2-Exc_L5-6_FEZF2_MYBPHL|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

HGF LUZP2

2.16e-03173182b002b22f9968b5967d29fe0eab4e796d87b355fa
ToppCellfacs-Liver-Non-hepatocytes-3m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BTLA IL21R

2.18e-03174182fbf998dd33ac27dad7639ea85fca393ba2835307
ToppCellfacs-Liver-Non-hepatocytes-3m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BTLA IL21R

2.18e-031741828bdf5a97faf1cf0426d1a8851f8a3e27578f7598
ToppCellmetastatic_Brain-T/NK_cells-Exhausted_Tfh|metastatic_Brain / Location, Cell class and cell subclass

NIPAL4 IL21R

2.21e-03175182b732c6a423c28856211002107d8c611dcfb6f265
ToppCellLPS-antiTNF-Lymphocytic_NKT-T_cells|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

BTLA IL21R

2.23e-03176182ea27e18407b8a13e8212830da859efeb8f158690
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_26.46.91|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NIPAL4 LUZP2

2.23e-0317618229b71369503719c74888cd356ceb6724cfdcabd9
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_B-B_Cell-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

BTLA IL21R

2.23e-03176182d0a3e176df1270968efa79c00dc941c5e1c4f7aa
ToppCellLPS-antiTNF-Lymphocytic_NKT-T_cells-T-cells|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

BTLA IL21R

2.23e-03176182bfbab3c5b738b3b0b1540f2059d0245fbd8c0031
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_B-B_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

BTLA IL21R

2.23e-03176182274458d80f9f3f080248cbf64e4784ef351e7254
ToppCell10x3'2.3-week_12-13-Myeloid_DC-DC-pDC|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

BTLA NCR2

2.26e-03177182e36c2005be74ee8ff03c2052504cb496faf86009
ToppCelldroplet-Tongue-nan-3m-Myeloid-Langerhans_cell|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BTLA IL21R

2.26e-0317718234bd46704827c9db7053bbd0c671dd0b661b79b4
ToppCelldroplet-Fat-Scat-18m-Lymphocytic-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BTLA IL21R

2.26e-0317718276be975de7ebb2f8f7ea642244757a6dd44acd72
ToppCelldroplet-Lung-1m-Hematologic-lymphocytic-Zbtb32+_B_cell|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CYP4F22 BTLA

2.26e-03177182a58c93be9767e3fe8fbb6b0db1210d3a33aac662
ToppCelldroplet-Fat-Scat-18m-Lymphocytic|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BTLA IL21R

2.26e-03177182872f05dca01e6d89a0b69d1a34840f09a2fa1948
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_CPZ|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LUZP2 IL21R

2.26e-0317718257033ee0d49a4a50fc25328a4a44d4de2b35f505
ToppCelldroplet-Lung-1m-Hematologic-lymphocytic-Zbtb32+_B_cell-Zbtb32+_B_cell|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CYP4F22 BTLA

2.26e-031771823ed383e5c0b15d9d5e75b98cf6d10609f48fc422
DrugMetanephrine hydrochloride DL [881-95-8]; Down 200; 17.2uM; HL60; HG-U133A

HGF CLN3 LMF2 NCR2

1.40e-051931842015_DN
DrugIobenguane sulfate; Up 200; 10.8uM; HL60; HG-U133A

HGF ADCY6 LMF2 NCR2

1.57e-051991841729_UP
Diseasepolymyositis (is_marker_for)

HGF TNFRSF1A

1.51e-0511162DOID:0080745 (is_marker_for)
DiseaseCongenital ichthyosis of skin

CYP4F22 NIPAL4

1.51e-0511162cv:C0020758
DiseaseCongenital Nonbullous Ichthyosiform Erythroderma

CYP4F22 NIPAL4

1.51e-0511162C0079154
Diseaseureteral obstruction (biomarker_via_orthology)

ADCY6 TNFRSF1A

2.69e-0445162DOID:5199 (biomarker_via_orthology)
Diseasecoronary artery disease (is_marker_for)

HGF TNFRSF1A

5.97e-0467162DOID:3393 (is_marker_for)
Diseaseplatelet measurement

SIRPD CLN3 TNFRSF1A

6.09e-04315163EFO_0005036
Diseasemultiple sclerosis (is_implicated_in)

IL21R TNFRSF1A

7.08e-0473162DOID:2377 (is_implicated_in)
Diseaseobesity (is_marker_for)

HGF TNFRSF1A

1.35e-03101162DOID:9970 (is_marker_for)
Diseaseprimary biliary cirrhosis

IL21R TNFRSF1A

2.32e-03133162EFO_1001486
Diseasecolorectal health

LUZP2 IL21R

5.20e-03201162EFO_0008460

Protein segments in the cluster

PeptideGeneStartEntry
YRLLPLGGLPLLITT

BTLA

156

Q7Z6A9
GLIYLVLLLLGPPAT

ADCY6

846

O43306
LHPLLLLLLLFPGSQ

NCR2

6

O95944
LLHLLLLPIAIPYAE

HGF

16

P14210
PQHLLPILFLLYLLM

OR10H4

21

Q8NGA5
AHYLLPLLPALVLST

LUZP2

6

Q86TE4
PHLLLLLLLVIVFIP

IL21R

236

Q9HBE5
LLVLVHPDYIKPLLG

CYP4F22

106

Q6NT55
LLTAPIPILTSLLHY

OR56A1

161

Q8NGH5
SLHIIVANLYLLLPP

OR52N5

281

Q8NH56
HVLLAILYRLVPPAL

OR52L2P

291

Q8NGH6
LLALLIILIGPFIYP

RNF186

161

Q9NXI6
GALLLSPLRHPVIYL

LMF2

91

Q9BU23
IKLLAPLGLHLLPYS

CLN3

111

Q13286
PLHITPLGLLLLILY

SLC35A4

181

Q96G79
PLPSLLLYLLLELAG

SIRPD

11

Q9H106
LLIILAPGPYLSLVL

TMEM86B

126

Q8N661
LPVVRHPLPYILSLI

NIPAL4

256

Q0D2K0
HPLPYILSLILALSL

NIPAL4

261

Q0D2K0
LPLVLLELLVGIYPS

TNFRSF1A

11

P19438