Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	voltage-gated sodium channel activity	SCN10A SCN11A SCN1A SCN2A SCN3A	6.75e-10	26	34	5	GO:0005248
GeneOntologyMolecularFunction	sodium channel activity	SCN10A SCN11A SCN1A SCN2A SCN3A	2.58e-08	52	34	5	GO:0005272
GeneOntologyMolecularFunction	sodium ion transmembrane transporter activity	SCN10A SCN11A SLC13A2 SCN1A SCN2A SCN3A	3.98e-07	171	34	6	GO:0015081
GeneOntologyMolecularFunction	sodium ion binding	SCN1A SCN2A SCN3A	1.62e-06	14	34	3	GO:0031402
GeneOntologyMolecularFunction	channel activity	SCN10A SCN11A CLCN6 SCN1A RHAG SCN2A SCN3A KCNJ12	2.15e-06	525	34	8	GO:0015267
GeneOntologyMolecularFunction	passive transmembrane transporter activity	SCN10A SCN11A CLCN6 SCN1A RHAG SCN2A SCN3A KCNJ12	2.18e-06	526	34	8	GO:0022803
GeneOntologyMolecularFunction	voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	SCN10A SCN1A SCN2A	3.02e-06	17	34	3	GO:0099508
GeneOntologyMolecularFunction	inorganic molecular entity transmembrane transporter activity	SCN10A SCN11A CLCN6 SLC13A2 SCN1A RHAG SCN2A SCN3A KCNJ12	3.49e-06	758	34	9	GO:0015318
GeneOntologyMolecularFunction	inorganic cation transmembrane transporter activity	SCN10A SCN11A SLC13A2 SCN1A RHAG SCN2A SCN3A KCNJ12	7.97e-06	627	34	8	GO:0022890
GeneOntologyMolecularFunction	monoatomic ion channel activity	SCN10A SCN11A CLCN6 SCN1A SCN2A SCN3A KCNJ12	1.02e-05	459	34	7	GO:0005216
GeneOntologyMolecularFunction	metal ion transmembrane transporter activity	SCN10A SCN11A SLC13A2 SCN1A SCN2A SCN3A KCNJ12	1.11e-05	465	34	7	GO:0046873
GeneOntologyMolecularFunction	alkali metal ion binding	SCN1A SCN2A SCN3A	1.14e-05	26	34	3	GO:0031420
GeneOntologyMolecularFunction	voltage-gated monoatomic ion channel activity	SCN10A CLCN6 SCN1A SCN2A KCNJ12	1.34e-05	182	34	5	GO:0005244
GeneOntologyMolecularFunction	voltage-gated channel activity	SCN10A CLCN6 SCN1A SCN2A KCNJ12	1.41e-05	184	34	5	GO:0022832
GeneOntologyMolecularFunction	transmembrane transporter activity	SCN10A SCN11A CLCN6 SLC13A2 SLC7A11 SCN1A RHAG SCN2A SCN3A KCNJ12	1.78e-05	1180	34	10	GO:0022857
GeneOntologyMolecularFunction	monoatomic cation channel activity	SCN10A SCN11A SCN1A SCN2A SCN3A KCNJ12	2.20e-05	343	34	6	GO:0005261
GeneOntologyMolecularFunction	transporter activity	SCN10A SCN11A CLCN6 SLC13A2 SLC7A11 SCN1A RHAG SCN2A SCN3A KCNJ12	3.81e-05	1289	34	10	GO:0005215
GeneOntologyMolecularFunction	monoatomic ion transmembrane transporter activity	SCN10A SCN11A CLCN6 SLC13A2 SCN1A SCN2A SCN3A KCNJ12	4.33e-05	793	34	8	GO:0015075
GeneOntologyMolecularFunction	monoatomic cation transmembrane transporter activity	SCN10A SCN11A SLC13A2 SCN1A SCN2A SCN3A KCNJ12	1.07e-04	664	34	7	GO:0008324
GeneOntologyMolecularFunction	gated channel activity	SCN10A CLCN6 SCN1A SCN2A KCNJ12	2.37e-04	334	34	5	GO:0022836
GeneOntologyBiologicalProcess	membrane depolarization during action potential	SCN10A SCN11A ANK2 SCN1A SCN2A SCN3A	2.37e-11	36	34	6	GO:0086010
GeneOntologyBiologicalProcess	cardiac muscle cell action potential involved in contraction	SCN10A SCN11A ANK2 SCN1A SCN2A SCN3A	7.25e-10	62	34	6	GO:0086002
GeneOntologyBiologicalProcess	actin filament-based movement	SCN10A SCN11A ANK2 MYO19 SCN1A SCN2A SCN3A	4.90e-09	153	34	7	GO:0030048
GeneOntologyBiologicalProcess	cardiac muscle cell action potential	SCN10A SCN11A ANK2 SCN1A SCN2A SCN3A	5.78e-09	87	34	6	GO:0086001
GeneOntologyBiologicalProcess	cardiac muscle cell contraction	SCN10A SCN11A ANK2 SCN1A SCN2A SCN3A	8.67e-09	93	34	6	GO:0086003
GeneOntologyBiologicalProcess	membrane depolarization	SCN10A SCN11A ANK2 SCN1A SCN2A SCN3A	4.23e-08	121	34	6	GO:0051899
GeneOntologyBiologicalProcess	actin-mediated cell contraction	SCN10A SCN11A ANK2 SCN1A SCN2A SCN3A	5.65e-08	127	34	6	GO:0070252
GeneOntologyBiologicalProcess	neuronal action potential	SCN10A SCN11A SCN1A SCN2A SCN3A	5.88e-08	63	34	5	GO:0019228
GeneOntologyBiologicalProcess	cardiac muscle contraction	SCN10A SCN11A ANK2 SCN1A SCN2A SCN3A	2.87e-07	167	34	6	GO:0060048
GeneOntologyBiologicalProcess	heart contraction	SCN10A SCN11A ANK2 SCN1A SCN2A SCN3A KCNJ12	4.72e-07	298	34	7	GO:0060047
GeneOntologyBiologicalProcess	heart process	SCN10A SCN11A ANK2 SCN1A SCN2A SCN3A KCNJ12	6.02e-07	309	34	7	GO:0003015
GeneOntologyBiologicalProcess	action potential	SCN10A SCN11A ANK2 SCN1A SCN2A SCN3A	8.52e-07	201	34	6	GO:0001508
GeneOntologyBiologicalProcess	sodium ion transmembrane transport	SCN10A SCN11A SLC13A2 SCN1A SCN2A SCN3A	1.04e-06	208	34	6	GO:0035725
GeneOntologyBiologicalProcess	transmission of nerve impulse	SCN10A SCN11A SCN1A SCN2A SCN3A	1.06e-06	112	34	5	GO:0019226
GeneOntologyBiologicalProcess	striated muscle contraction	SCN10A SCN11A ANK2 SCN1A SCN2A SCN3A	1.33e-06	217	34	6	GO:0006941
GeneOntologyBiologicalProcess	muscle contraction	SCN10A SCN11A ANK2 SCN1A SCN2A SCN3A KCNJ12	3.35e-06	400	34	7	GO:0006936
GeneOntologyBiologicalProcess	inorganic ion transmembrane transport	SCN10A SCN11A ANK2 CLCN6 SLC13A2 SCN1A RHAG SCN2A SCN3A KCNJ12	3.61e-06	1017	34	10	GO:0098660
GeneOntologyBiologicalProcess	sodium ion transport	SCN10A SCN11A SLC13A2 SCN1A SCN2A SCN3A	5.23e-06	275	34	6	GO:0006814
GeneOntologyBiologicalProcess	inorganic cation transmembrane transport	SCN10A SCN11A ANK2 SLC13A2 SCN1A RHAG SCN2A SCN3A KCNJ12	1.31e-05	922	34	9	GO:0098662
GeneOntologyBiologicalProcess	regulation of glutamate metabolic process	APC SLC7A11	1.58e-05	4	34	2	GO:2000211
GeneOntologyBiologicalProcess	behavioral response to pain	SCN10A SCN11A SCN3A	1.96e-05	32	34	3	GO:0048266
GeneOntologyBiologicalProcess	muscle system process	SCN10A SCN11A ANK2 SCN1A SCN2A SCN3A KCNJ12	2.56e-05	547	34	7	GO:0003012
GeneOntologyBiologicalProcess	detection of stimulus involved in sensory perception of pain	SCN10A SCN11A SCN1A	4.83e-05	43	34	3	GO:0062149
GeneOntologyBiologicalProcess	monoatomic ion transmembrane transport	SCN10A SCN11A ANK2 CLCN6 SLC13A2 SCN1A SCN2A SCN3A KCNJ12	5.86e-05	1115	34	9	GO:0034220
GeneOntologyBiologicalProcess	regulation of glutamine family amino acid metabolic process	APC SLC7A11	7.34e-05	8	34	2	GO:0000820
GeneOntologyBiologicalProcess	blood circulation	SCN10A SCN11A ANK2 SCN1A SCN2A SCN3A KCNJ12	7.51e-05	648	34	7	GO:0008015
GeneOntologyBiologicalProcess	response to pain	SCN10A SCN11A SCN3A	8.07e-05	51	34	3	GO:0048265
GeneOntologyBiologicalProcess	actin filament-based process	SCN10A SCN11A ANK2 MYO19 SCN1A SCN2A SCN3A IQSEC2	9.22e-05	912	34	8	GO:0030029
GeneOntologyBiologicalProcess	detection of mechanical stimulus involved in sensory perception	SCN10A SCN11A SCN1A	1.13e-04	57	34	3	GO:0050974
GeneOntologyBiologicalProcess	monoatomic cation transmembrane transport	SCN10A SCN11A ANK2 SLC13A2 SCN1A SCN2A SCN3A KCNJ12	1.16e-04	942	34	8	GO:0098655
GeneOntologyBiologicalProcess	circulatory system process	SCN10A SCN11A ANK2 SCN1A SCN2A SCN3A KCNJ12	1.62e-04	733	34	7	GO:0003013
GeneOntologyBiologicalProcess	AV node cell to bundle of His cell signaling	SCN10A ANK2	1.72e-04	12	34	2	GO:0086027
GeneOntologyBiologicalProcess	AV node cell action potential	SCN10A ANK2	1.72e-04	12	34	2	GO:0086016
GeneOntologyBiologicalProcess	metal ion transport	SCN10A SCN11A ANK2 SLC13A2 SCN1A SCN2A SCN3A KCNJ12	1.75e-04	1000	34	8	GO:0030001
GeneOntologyBiologicalProcess	detection of mechanical stimulus	SCN10A SCN11A SCN1A	2.55e-04	75	34	3	GO:0050982
GeneOntologyBiologicalProcess	regulation of membrane potential	SCN10A SCN11A ANK2 SCN1A SCN2A SCN3A	2.72e-04	559	34	6	GO:0042391
GeneOntologyBiologicalProcess	AV node cell to bundle of His cell communication	SCN10A ANK2	2.73e-04	15	34	2	GO:0086067
GeneOntologyBiologicalProcess	monoatomic ion transport	SCN10A SCN11A ANK2 CLCN6 SLC13A2 SCN1A SCN2A SCN3A KCNJ12	2.88e-04	1374	34	9	GO:0006811
GeneOntologyBiologicalProcess	regulation of amino acid metabolic process	APC SLC7A11	3.97e-04	18	34	2	GO:0006521
GeneOntologyBiologicalProcess	monoatomic cation transport	SCN10A SCN11A ANK2 SLC13A2 SCN1A SCN2A SCN3A KCNJ12	4.69e-04	1157	34	8	GO:0006812
GeneOntologyBiologicalProcess	sensory perception of pain	SCN10A SCN11A SCN1A	6.84e-04	105	34	3	GO:0019233
GeneOntologyBiologicalProcess	response to mechanical stimulus	SCN10A SCN11A CLCN6 SCN1A	7.02e-04	247	34	4	GO:0009612
GeneOntologyBiologicalProcess	detection of mechanical stimulus involved in sensory perception of pain	SCN11A SCN1A	8.36e-04	26	34	2	GO:0050966
GeneOntologyBiologicalProcess	detection of temperature stimulus involved in sensory perception of pain	SCN10A SCN11A	8.36e-04	26	34	2	GO:0050965
GeneOntologyBiologicalProcess	detection of temperature stimulus involved in sensory perception	SCN10A SCN11A	1.11e-03	30	34	2	GO:0050961
GeneOntologyBiologicalProcess	multicellular organismal response to stress	SCN10A SCN11A SCN3A	1.16e-03	126	34	3	GO:0033555
GeneOntologyBiologicalProcess	regulation of presynaptic membrane potential	SCN10A SCN1A	1.27e-03	32	34	2	GO:0099505
GeneOntologyBiologicalProcess	detection of temperature stimulus	SCN10A SCN11A	1.35e-03	33	34	2	GO:0016048
GeneOntologyBiologicalProcess	cell-cell signaling involved in cardiac conduction	SCN10A ANK2	1.43e-03	34	34	2	GO:0086019
GeneOntologyBiologicalProcess	sensory perception of temperature stimulus	SCN10A SCN11A	1.79e-03	38	34	2	GO:0050951
GeneOntologyBiologicalProcess	glutamate metabolic process	APC SLC7A11	1.79e-03	38	34	2	GO:0006536
GeneOntologyCellularComponent	voltage-gated sodium channel complex	SCN10A SCN11A SCN1A SCN2A SCN3A	5.11e-11	17	34	5	GO:0001518
GeneOntologyCellularComponent	sodium channel complex	SCN10A SCN11A SCN1A SCN2A SCN3A	9.67e-10	29	34	5	GO:0034706
GeneOntologyCellularComponent	T-tubule	ANK2 SCN1A SCN2A KCNJ12	8.04e-06	79	34	4	GO:0030315
GeneOntologyCellularComponent	C-fiber	SCN10A SCN11A	1.54e-05	4	34	2	GO:0044299
GeneOntologyCellularComponent	monoatomic ion channel complex	SCN10A SCN11A SCN1A SCN2A SCN3A KCNJ12	2.94e-05	378	34	6	GO:0034702
GeneOntologyCellularComponent	synaptic membrane	SCN10A SCN11A RAPSN ANK2 SCN1A SCN2A IQSEC2	3.54e-05	583	34	7	GO:0097060
GeneOntologyCellularComponent	cation channel complex	SCN10A SCN11A SCN1A SCN2A SCN3A	3.67e-05	235	34	5	GO:0034703
GeneOntologyCellularComponent	transmembrane transporter complex	SCN10A SCN11A SCN1A SCN2A SCN3A KCNJ12	1.77e-04	523	34	6	GO:1902495
GeneOntologyCellularComponent	intercalated disc	ANK2 SCN1A SCN2A	1.83e-04	68	34	3	GO:0014704
GeneOntologyCellularComponent	plasma membrane protein complex	SCN10A APC SCN11A ITGAD SCN1A SCN2A SCN3A	2.27e-04	785	34	7	GO:0098797
GeneOntologyCellularComponent	transporter complex	SCN10A SCN11A SCN1A SCN2A SCN3A KCNJ12	2.32e-04	550	34	6	GO:1990351
GeneOntologyCellularComponent	sarcolemma	ANK2 SCN1A SCN2A KCNJ12	2.48e-04	190	34	4	GO:0042383
GeneOntologyCellularComponent	cell-cell contact zone	ANK2 SCN1A SCN2A	4.76e-04	94	34	3	GO:0044291
GeneOntologyCellularComponent	node of Ranvier	SCN1A SCN2A	4.79e-04	20	34	2	GO:0033268
GeneOntologyCellularComponent	membrane protein complex	SCN10A APC SCN11A ITGAD SCN1A RHAG SCN2A SCN3A KCNJ12	4.95e-04	1498	34	9	GO:0098796
GeneOntologyCellularComponent	axon initial segment	SCN1A SCN2A	1.01e-03	29	34	2	GO:0043194
GeneOntologyCellularComponent	presynaptic membrane	SCN10A SCN11A SCN1A SCN2A	1.02e-03	277	34	4	GO:0042734
GeneOntologyCellularComponent	glutamatergic synapse	SCN10A DOCK10 APC SCN11A SCN2A IQSEC2	1.84e-03	817	34	6	GO:0098978
GeneOntologyCellularComponent	axonal growth cone	APC SCN11A	2.43e-03	45	34	2	GO:0044295
GeneOntologyCellularComponent	presynapse	SCN10A APC SCN11A SCN1A SCN2A IQSEC2	2.77e-03	886	34	6	GO:0098793
GeneOntologyCellularComponent	axon	SCN10A APC SCN11A SCN1A SCN2A SCN3A	2.85e-03	891	34	6	GO:0030424
GeneOntologyCellularComponent	somatodendritic compartment	DOCK10 APC BPTF SCN11A SCN1A SCN3A KCNJ12	3.15e-03	1228	34	7	GO:0036477
GeneOntologyCellularComponent	cell body	APC BPTF SCN11A SCN1A SCN3A KCNJ12	3.51e-03	929	34	6	GO:0044297
Domain	Na_channel_asu	SCN10A SCN11A SCN1A SCN2A SCN3A	3.14e-12	10	33	5	IPR001696
Domain	Na_trans_assoc	SCN10A SCN11A SCN1A SCN2A SCN3A	3.14e-12	10	33	5	IPR010526
Domain	Na_trans_assoc	SCN10A SCN11A SCN1A SCN2A SCN3A	3.14e-12	10	33	5	PF06512
Domain	IQ_motif_EF-hand-BS	SCN10A MYO19 SCN1A SCN2A SCN3A IQSEC2	1.05e-08	90	33	6	IPR000048
Domain	IQ	SCN10A MYO19 SCN1A SCN2A SCN3A IQSEC2	1.29e-08	93	33	6	PS50096
Domain	Channel_four-helix_dom	SCN10A SCN11A SCN1A SCN2A SCN3A	4.92e-08	57	33	5	IPR027359
Domain	-	SCN10A SCN11A SCN1A SCN2A SCN3A	4.92e-08	57	33	5	1.20.120.350
Domain	Na_trans_cytopl	SCN1A SCN2A SCN3A	1.00e-07	6	33	3	PF11933
Domain	Na_trans_cytopl	SCN1A SCN2A SCN3A	1.00e-07	6	33	3	IPR024583
Domain	Ion_trans_dom	SCN10A SCN11A SCN1A SCN2A SCN3A	1.61e-06	114	33	5	IPR005821
Domain	Ion_trans	SCN10A SCN11A SCN1A SCN2A SCN3A	1.61e-06	114	33	5	PF00520
Domain	IQ	SCN10A SCN1A SCN3A IQSEC2	7.22e-06	71	33	4	PF00612
Domain	IQ	MYO19 SCN1A SCN2A SCN3A	1.22e-05	81	33	4	SM00015
Domain	F-box_dom	FBXW10B FBXW10	7.75e-03	75	33	2	IPR001810
Domain	G-protein_beta_WD-40_rep	FBXW10B FBXW10	9.86e-03	85	33	2	IPR020472
Domain	TPR_1	RAPSN CNOT10	1.10e-02	90	33	2	PF00515
Domain	TPR_1	RAPSN CNOT10	1.10e-02	90	33	2	IPR001440
Pathway	REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS	SCN10A SCN11A ANK2 SCN1A SCN2A SCN3A	4.79e-11	31	31	6	M877
Pathway	REACTOME_PHASE_0_RAPID_DEPOLARISATION	SCN10A SCN11A SCN1A SCN2A SCN3A	7.08e-09	32	31	5	M27455
Pathway	REACTOME_L1CAM_INTERACTIONS	SCN10A SCN11A ANK2 SCN1A SCN2A SCN3A	2.18e-07	121	31	6	M872
Pathway	REACTOME_CARDIAC_CONDUCTION	SCN10A SCN11A SCN1A SCN2A SCN3A KCNJ12	3.34e-07	130	31	6	M27454
Pathway	REACTOME_MUSCLE_CONTRACTION	SCN10A SCN11A SCN1A SCN2A SCN3A KCNJ12	4.52e-06	203	31	6	M5485
Pathway	WP_DRAVET_SYNDROME	SCN1A SCN2A SCN3A	3.04e-05	28	31	3	M45519
Pubmed	International Union of Pharmacology. XLVII. Nomenclature and structure-function relationships of voltage-gated sodium channels.	SCN10A SCN11A SCN1A SCN2A SCN3A	8.25e-14	9	34	5	16382098
Pubmed	A 'toothache tree' alkylamide inhibits Aδ mechanonociceptors to alleviate mechanical pain.	SCN10A SCN1A SCN2A SCN3A	1.14e-11	6	34	4	23652591
Pubmed	Regulation of neuronal voltage-gated sodium channels by the ubiquitin-protein ligases Nedd4 and Nedd4-2.	SCN10A SCN1A SCN2A SCN3A	5.41e-10	13	34	4	15123669
Pubmed	Sodium channels SCN1A, SCN2A and SCN3A in familial autism.	SCN1A SCN2A SCN3A	8.54e-10	3	34	3	12610651
Pubmed	SCN1A, SCN2A and SCN3A gene polymorphisms and responsiveness to antiepileptic drugs: a multicenter cohort study and meta-analysis.	SCN1A SCN2A SCN3A	8.54e-10	3	34	3	23859570
Pubmed	Early expression of sodium channel transcripts and sodium current by cajal-retzius cells in the preplate of the embryonic mouse neocortex.	SCN1A SCN2A SCN3A	8.54e-10	3	34	3	14973256
Pubmed	Multidrug resistance in epilepsy and polymorphisms in the voltage-gated sodium channel genes SCN1A, SCN2A, and SCN3A: correlation among phenotype, genotype, and mRNA expression.	SCN1A SCN2A SCN3A	8.54e-10	3	34	3	18784617
Pubmed	Characterization of 5' untranslated regions of the voltage-gated sodium channels SCN1A, SCN2A, and SCN3A and identification of cis-conserved noncoding sequences.	SCN1A SCN2A SCN3A	8.54e-10	3	34	3	17544618
Pubmed	Nav1.1 localizes to axons of parvalbumin-positive inhibitory interneurons: a circuit basis for epileptic seizures in mice carrying an Scn1a gene mutation.	SCN1A SCN2A SCN3A	3.41e-09	4	34	3	17537961
Pubmed	Sodium channel expression and transcript variation in the developing brain of human, Rhesus monkey, and mouse.	SCN1A SCN2A SCN3A	3.41e-09	4	34	3	35031483
Pubmed	Abnormal changes in voltage-gated sodium channels subtypes NaV1.1, NaV1.2, NaV1.3, NaV1.6 and CaM/CaMKII pathway in low-grade astrocytoma.	SCN1A SCN2A SCN3A	3.41e-09	4	34	3	29578003
Pubmed	Association of sodium voltage-gated channel genes polymorphisms with epilepsy risk and prognosis in the Saudi population.	SCN1A SCN2A SCN3A	3.41e-09	4	34	3	35801810
Pubmed	Use of recombinant inbred strains for studying genetic determinants of responses to alcohol.	SCN1A SCN2A SCN3A	3.41e-09	4	34	3	8974318
Pubmed	Three brain sodium channel alpha-subunit genes are clustered on the proximal segment of mouse chromosome 2.	SCN1A SCN2A SCN3A	8.52e-09	5	34	3	1679748
Pubmed	A new sodium channel alpha-subunit gene (Scn9a) from Schwann cells maps to the Scn1a, Scn2a, Scn3a cluster of mouse chromosome 2.	SCN1A SCN2A SCN3A	8.52e-09	5	34	3	8812438
Pubmed	Case-control association study of polymorphisms in the voltage-gated sodium channel genes SCN1A, SCN2A, SCN3A, SCN1B, and SCN2B and epilepsy.	SCN1A SCN2A SCN3A	8.52e-09	5	34	3	24337656
Pubmed	An animal model of oxaliplatin-induced cold allodynia reveals a crucial role for Nav1.6 in peripheral pain pathways.	SCN10A SCN11A SCN3A	1.70e-08	6	34	3	23711479
Pubmed	Pain without nociceptors? Nav1.7-independent pain mechanisms.	SCN10A SCN11A SCN3A	2.98e-08	7	34	3	24440715
Pubmed	Significant determinants of mouse pain behaviour.	SCN10A SCN11A SCN3A	4.76e-08	8	34	3	25101983
Pubmed	Expression pattern of neuronal and skeletal muscle voltage-gated Na+ channels in the developing mouse heart.	SCN1A SCN2A SCN3A	7.14e-08	9	34	3	15746173
Pubmed	Quantitative trait loci mapping of genes that influence the sensitivity and tolerance to ethanol-induced hypothermia in BXD recombinant inbred mice.	SCN1A SCN2A SCN3A	1.87e-07	12	34	3	8169823
Pubmed	Nav1.2 haplodeficiency in excitatory neurons causes absence-like seizures in mice.	SCN1A SCN2A SCN3A	1.87e-07	12	34	3	30175250
Pubmed	Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development.	SCN10A SCN11A CLCN6 SCN1A SCN3A	2.40e-07	139	34	5	16985003
Pubmed	Confirmation of quantitative trait loci for alcohol preference in mice.	SCN1A SCN2A SCN3A	3.85e-07	15	34	3	9726281
Pubmed	Sodium Channel Nav1.8 Underlies TTX-Resistant Axonal Action Potential Conduction in Somatosensory C-Fibers of Distal Cutaneous Nerves.	SCN10A SCN11A	9.28e-07	2	34	2	28450535
Pubmed	Association between SCN1A and SCN2A mutations and clinical/EEG features in Chinese patients from epilepsy or severe seizures.	SCN1A SCN2A	9.28e-07	2	34	2	29649454
Pubmed	Array-CGH detection of a de novo 2.8 Mb deletion in 2q24.2-->q24.3 in a girl with autistic features and developmental delay.	SCN2A SCN3A	9.28e-07	2	34	2	20346423
Pubmed	Heat-resistant action potentials require TTX-resistant sodium channels NaV1.8 and NaV1.9.	SCN10A SCN11A	9.28e-07	2	34	2	29970412
Pubmed	Missense mutations in sodium channel SCN1A and SCN2A predispose children to encephalopathy with severe febrile seizures.	SCN1A SCN2A	9.28e-07	2	34	2	26311622
Pubmed	Elevated FBXW10 drives hepatocellular carcinoma tumorigenesis via AR-VRK2 phosphorylation-dependent GAPDH ubiquitination in male transgenic mice.	FBXW10B FBXW10	9.28e-07	2	34	2	37450367
Pubmed	Exploring the role of nociceptor-specific sodium channels in pain transmission using Nav1.8 and Nav1.9 knockout mice.	SCN10A SCN11A	9.28e-07	2	34	2	19931571
Pubmed	Tetrodotoxin-resistant voltage-gated sodium channels Na(v)1.8 and Na(v)1.9 are expressed in the retina.	SCN10A SCN11A	9.28e-07	2	34	2	18399542
Pubmed	Correlation of Nav1.8 and Nav1.9 sodium channel expression with neuropathic pain in human subjects with lingual nerve neuromas.	SCN10A SCN11A	9.28e-07	2	34	2	24144460
Pubmed	Contributions of NaV1.8 and NaV1.9 to excitability in human induced pluripotent stem-cell derived somatosensory neurons.	SCN10A SCN11A	9.28e-07	2	34	2	34930944
Pubmed	Dissecting the role of sodium currents in visceral sensory neurons in a model of chronic hyperexcitability using Nav1.8 and Nav1.9 null mice.	SCN10A SCN11A	9.28e-07	2	34	2	16857712
Pubmed	Neuronal death and perinatal lethality in voltage-gated sodium channel alpha(II)-deficient mice.	SCN1A SCN2A	9.28e-07	2	34	2	10827969
Pubmed	Severe epilepsy, retardation, and dysmorphic features with a 2q deletion including SCN1A and SCN2A.	SCN1A SCN2A	9.28e-07	2	34	2	15249644
Pubmed	Mapping of a FEB3 homologous febrile seizure locus on mouse chromosome 2 containing candidate genes Scn1a and Scn3a.	SCN1A SCN3A	9.28e-07	2	34	2	27690330
Pubmed	Differential role of sodium channels SCN1A and SCN2A gene polymorphisms with epilepsy and multiple drug resistance in the north Indian population.	SCN1A SCN2A	9.28e-07	2	34	2	19694741
Pubmed	Genomic structures of SCN2A and SCN3A - candidate genes for deafness at the DFNA16 locus.	SCN2A SCN3A	9.28e-07	2	34	2	11245985
Pubmed	The Nav1.9 channel is a key determinant of cold pain sensation and cold allodynia.	SCN10A SCN11A	9.28e-07	2	34	2	25959819
Pubmed	Maladaptive activation of Nav1.9 channels by nitric oxide causes triptan-induced medication overuse headache.	SCN10A SCN11A	9.28e-07	2	34	2	31534133
Pubmed	The developmental changes of Na(v)1.1 and Na(v)1.2 expression in the human hippocampus and temporal lobe.	SCN1A SCN2A	9.28e-07	2	34	2	21377452
Pubmed	Differential expression of two sodium channel subtypes in human brain.	SCN1A SCN2A	9.28e-07	2	34	2	1317301
Pubmed	FBXW10 promotes hepatocarcinogenesis in male patients and mice.	FBXW10B FBXW10	9.28e-07	2	34	2	31400758
Pubmed	Correlations in timing of sodium channel expression, epilepsy, and sudden death in Dravet syndrome.	SCN1A SCN3A	9.28e-07	2	34	2	23965409
Pubmed	Duplication of the sodium channel gene cluster on 2q24 in children with early onset epilepsy.	SCN2A SCN3A	9.28e-07	2	34	2	23016767
Pubmed	Whole gene duplication of SCN2A and SCN3A is associated with neonatal seizures and a normal intellectual development.	SCN2A SCN3A	9.28e-07	2	34	2	27153334
Pubmed	Effects of SCN1A and SCN2A polymorphisms on responsiveness to valproic acid monotherapy in epileptic children.	SCN1A SCN2A	9.28e-07	2	34	2	33096315
Pubmed	Electrophysiological Differences between the Same Pore Region Mutation in SCN1A and SCN3A.	SCN1A SCN3A	9.28e-07	2	34	2	24990319
Pubmed	Clinical exome sequencing identifies two novel mutations of the SCN1A and SCN2A genes in Moroccan patients with epilepsy: a case series.	SCN1A SCN2A	9.28e-07	2	34	2	31439038
Pubmed	SCN1A and SCN2A polymorphisms are associated with response to valproic acid in Chinese epilepsy patients.	SCN1A SCN2A	9.28e-07	2	34	2	30693367
Pubmed	HIF-2α activation potentiates oxidative cell death in colorectal cancers by increasing cellular iron.	APC SLC7A11	2.78e-06	3	34	2	33914705
Pubmed	Voltage-gated sodium channels in taste bud cells.	SCN2A SCN3A	2.78e-06	3	34	2	19284629
Pubmed	Gene-to-gene interaction between sodium channel-related genes in determining the risk of antiepileptic drug resistance.	SCN1A SCN2A	2.78e-06	3	34	2	19270815
Pubmed	Physical and functional convergence of the autism risk genes Scn2a and Ank2 in neocortical pyramidal cell dendrites.	ANK2 SCN2A	2.78e-06	3	34	2	38290518
Pubmed	Nav1.2 is expressed in caudal ganglionic eminence-derived disinhibitory interneurons: Mutually exclusive distributions of Nav1.1 and Nav1.2.	SCN1A SCN2A	2.78e-06	3	34	2	28784306
Pubmed	Identification of functional voltage-gated Na(+) channels in cultured human pulmonary artery smooth muscle cells.	SCN2A SCN3A	2.78e-06	3	34	2	16052353
Pubmed	Association of SCN1A, SCN2A, and UGT2B7 Polymorphisms with Responsiveness to Valproic Acid in the Treatment of Epilepsy.	SCN1A SCN2A	2.78e-06	3	34	2	32185219
Pubmed	Genetic Analysis of SCN11A, SCN10A, and SCN9A in Familial Episodic Pain Syndrome (FEPS) in Japan and Proposal of Clinical Diagnostic Criteria.	SCN10A SCN11A	2.78e-06	3	34	2	38999942
Pubmed	Clinical exome sequencing as the first-tier test for diagnosing developmental disorders covering both CNV and SNV: a Chinese cohort.	SCN1A SCN2A	2.78e-06	3	34	2	32005694
Pubmed	Association of SCN1A, SCN2A and ABCC2 gene polymorphisms with the response to antiepileptic drugs in Chinese Han patients with epilepsy.	SCN1A SCN2A	2.78e-06	3	34	2	25155934
Pubmed	Mutations in the sodium channel genes SCN1A, SCN3A, and SCN9A in children with epilepsy with febrile seizures plus(EFS+).	SCN1A SCN3A	2.78e-06	3	34	2	33895391
Pubmed	A disease mutation reveals a role for NaV1.9 in acute itch.	SCN10A SCN11A	2.78e-06	3	34	2	30395542
Pubmed	Reduced sodium current in Purkinje neurons from Nav1.1 mutant mice: implications for ataxia in severe myoclonic epilepsy in infancy.	SCN1A SCN2A	2.78e-06	3	34	2	17928448
Pubmed	Yield of peripheral sodium channels gene screening in pure small fibre neuropathy.	SCN10A SCN11A	2.78e-06	3	34	2	30554136
Pubmed	Abnormal expression of voltage-gated sodium channels Nav1.7, Nav1.3 and Nav1.8 in trigeminal neuralgia.	SCN10A SCN3A	2.78e-06	3	34	2	19699781
Pubmed	Nerve injury induces robust allodynia and ectopic discharges in Nav1.3 null mutant mice.	SCN10A SCN3A	2.78e-06	3	34	2	17052333
Pubmed	Variable patterns of mutation density among NaV1.1, NaV1.2 and NaV1.6 point to channel-specific functional differences associated with childhood epilepsy.	SCN1A SCN2A	2.78e-06	3	34	2	32845893
Pubmed	Comparison and optimization of in silico algorithms for predicting the pathogenicity of sodium channel variants in epilepsy.	SCN1A SCN2A	2.78e-06	3	34	2	28518218
Pubmed	GAPDH-mediated posttranscriptional regulations of sodium channel Scn1a and Scn3a genes under seizure and ketogenic diet conditions.	SCN1A SCN3A	2.78e-06	3	34	2	27816501
Pubmed	Targeted DNA Sequencing from Autism Spectrum Disorder Brains Implicates Multiple Genetic Mechanisms.	SCN1A SCN2A	5.56e-06	4	34	2	26637798
Pubmed	Neuronal voltage-gated ion channels are genetic modifiers of generalized epilepsy with febrile seizures plus.	SCN1A SCN2A	5.56e-06	4	34	2	21156207
Pubmed	Dorsal root ganglia isolated from Nf1+/- mice exhibit increased levels of mRNA expression of voltage-dependent sodium channels.	SCN10A SCN1A	5.56e-06	4	34	2	22260870
Pubmed	Pain-causing stinging nettle toxins target TMEM233 to modulate NaV1.7 function.	SCN10A SCN11A	9.26e-06	5	34	2	37117223
Pubmed	FBXW10-S6K1 promotes ANXA2 polyubiquitination and KRAS activation to drive hepatocellular carcinoma development in males.	FBXW10B FBXW10	9.26e-06	5	34	2	37277019
Pubmed	Early development of electrical excitability in the mouse enteric nervous system.	SCN11A SCN3A	9.26e-06	5	34	2	22875929
Pubmed	Structure/function characterization of micro-conotoxin KIIIA, an analgesic, nearly irreversible blocker of mammalian neuronal sodium channels.	SCN2A SCN3A	9.26e-06	5	34	2	17724025
Pubmed	Protein interaction studies in human induced neurons indicate convergent biology underlying autism spectrum disorders.	APC ANK2 SCN2A	1.03e-05	43	34	3	36950384
Pubmed	Contactin regulates the current density and axonal expression of tetrodotoxin-resistant but not tetrodotoxin-sensitive sodium channels in DRG neurons.	SCN10A SCN11A	1.39e-05	6	34	2	16029194
Pubmed	LncGata6 maintains stemness of intestinal stem cells and promotes intestinal tumorigenesis.	APC BPTF	1.39e-05	6	34	2	30224759
Pubmed	Are voltage-dependent ion channels involved in the endothelial cell control of vasomotor tone?	SCN11A SCN2A	1.39e-05	6	34	2	17513486
Pubmed	Tyrosine-phosphorylated and nonphosphorylated sodium channel beta1 subunits are differentially localized in cardiac myocytes.	ANK2 SCN1A	1.94e-05	7	34	2	15272007
Pubmed	Diagnostic yield of genetic testing in epileptic encephalopathy in childhood.	SCN1A SCN2A	1.94e-05	7	34	2	25818041
Pubmed	A role for Piezo2 in EPAC1-dependent mechanical allodynia.	SCN10A SCN11A	1.94e-05	7	34	2	23575686
Pubmed	Genetic mapping of the peripheral sodium channel genes, Scn9a and Scn10a, in the mouse.	SCN10A SCN3A	3.33e-05	9	34	2	8854872
Pubmed	Sodium channel Scn1b null mice exhibit prolonged QT and RR intervals.	ANK2 SCN1A	3.33e-05	9	34	2	17884088
Pubmed	TBR1 regulates autism risk genes in the developing neocortex.	ANK2 SCN2A	3.33e-05	9	34	2	27325115
Pubmed	Common variants associated with general and MMR vaccine-related febrile seizures.	SCN1A SCN2A	4.15e-05	10	34	2	25344690
Pubmed	Genetic profile of patients with epilepsy on first-line antiepileptic drugs and potential directions for personalized treatment.	SCN1A SCN2A	4.15e-05	10	34	2	20602612
Pubmed	Report and abstracts of the Fourth International Workshop on Human Chromosome 2 Mapping 1996.	SCN1A SCN2A SCN3A	4.66e-05	71	34	3	8751373
Pubmed	WAVE1 is required for oligodendrocyte morphogenesis and normal CNS myelination.	APC SCN2A	7.19e-05	13	34	2	16723544
Pubmed	Selective disruption of trigeminal sensory neurogenesis and differentiation in a mouse model of 22q11.2 deletion syndrome.	SCN10A SCN11A	9.66e-05	15	34	2	33722956
Pubmed	Kv7/KCNQ potassium channels in cortical hyperexcitability and juvenile seizure-related death in Ank2-mutant mice.	ANK2 SCN2A	1.41e-04	18	34	2	37321992
Pubmed	An enhancer cluster controls gene activity and topology of the SCN5A-SCN10A locus in vivo.	SCN10A SCN11A	1.41e-04	18	34	2	31666509
Pubmed	A major quantitative trait locus on chromosome 3 controls colitis severity in IL-10-deficient mice.	APC ICOS	1.57e-04	19	34	2	11707574
Pubmed	ZBTB20 regulates nociception and pain sensation by modulating TRP channel expression in nociceptive sensory neurons.	SCN10A SCN11A	1.93e-04	21	34	2	25369838
Pubmed	Runx1 determines nociceptive sensory neuron phenotype and is required for thermal and neuropathic pain.	SCN10A SCN11A	2.32e-04	23	34	2	16446141
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	SIK2 DOCK10 APC MYO19 TUBGCP3	3.99e-04	650	34	5	38777146
Pubmed	Direction selectivity in the retina is established independent of visual experience and cholinergic retinal waves.	SCN10A SCN11A	5.41e-04	35	34	2	18498732
Interaction	SCN10A interactions	SCN10A SCN11A SCN1A	7.17e-07	11	34	3	int:SCN10A
Interaction	SCN11A interactions	SCN10A SCN11A SCN1A	1.97e-06	15	34	3	int:SCN11A
Interaction	FBXW10B interactions	FBXW10B FBXW10	8.28e-06	3	34	2	int:FBXW10B
Interaction	CACNA1D interactions	SCN10A SCN11A SCN1A	8.67e-06	24	34	3	int:CACNA1D
Interaction	SCN1A interactions	SCN10A SCN11A SCN1A	1.56e-05	29	34	3	int:SCN1A
Interaction	SCN5A interactions	SCN10A SCN11A SCN1A	6.76e-05	47	34	3	int:SCN5A
Interaction	SCN4B interactions	SCN1A SCN2A	7.69e-05	8	34	2	int:SCN4B
Interaction	PPP1R12B interactions	SIK2 ANK2 MYO19	2.04e-04	68	34	3	int:PPP1R12B
Interaction	FBXW10 interactions	FBXW10B FBXW10	2.13e-04	13	34	2	int:FBXW10
Interaction	NALCN interactions	SCN11A SCN1A	2.48e-04	14	34	2	int:NALCN
Interaction	CLTB interactions	SIK2 BMP2K MYO19 FAM83B	2.57e-04	185	34	4	int:CLTB
Interaction	SYNPO interactions	APC BMP2K MYO19 CD109	2.96e-04	192	34	4	int:SYNPO
Cytoband	2q24.3	SCN1A SCN2A	6.35e-05	16	34	2	2q24.3
Cytoband	Ensembl 112 genes in cytogenetic band chr2q24	SCN1A SCN2A SCN3A	1.16e-04	127	34	3	chr2q24
Cytoband	3p22.2	SCN10A SCN11A	1.45e-04	24	34	2	3p22.2
Cytoband	Ensembl 112 genes in cytogenetic band chr3p22	SCN10A SCN11A CNOT10	3.46e-04	184	34	3	chr3p22
Cytoband	17p12	FBXW10B FBXW10	6.13e-04	49	34	2	17p12
Cytoband	Ensembl 112 genes in cytogenetic band chr6p12	RHAG FAM83B	4.99e-03	142	34	2	chr6p12
Cytoband	Ensembl 112 genes in cytogenetic band chr17p11	FBXW10 KCNJ12	9.95e-03	203	34	2	chr17p11
GeneFamily	Sodium voltage-gated channel alpha subunits	SCN10A SCN11A SCN1A SCN2A SCN3A	6.30e-13	9	27	5	1203
GeneFamily	WD repeat domain containing\|F-box and WD repeat domain containing	FBXW10B FBXW10	1.17e-04	11	27	2	559
GeneFamily	ADAM metallopeptidase domain containing\|CD molecules	ICOS ITGAD RHAG CD109	2.62e-03	394	27	4	471
GeneFamily	Solute carriers	SLC13A2 SLC7A11 RHAG	2.05e-02	395	27	3	752
ToppCell	facs-Marrow-B-cells-3m-Myeloid-CD4+_macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	APC FADS3 ITGAD BMP2K SCN3A	2.46e-07	180	34	5	bf8d13d4db1af55b8c9fe16aaccf8743e000e005
ToppCell	facs-Marrow-B-cells-3m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	APC FADS3 ITGAD BMP2K SCN3A	2.46e-07	180	34	5	839defb40f7cfb2711e9025194de636533f51bcd
ToppCell	facs-Marrow-B-cells-3m-Myeloid-macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	APC FADS3 ITGAD BMP2K SCN3A	2.46e-07	180	34	5	82965ed1b72a1873c24dd4553d39681596057316
ToppCell	BAL-Severe-cDC_5\|Severe / Compartment, Disease Groups and Clusters	FBXW10B RAPSN SLC7A11 CD109	7.97e-06	168	34	4	857a80c217a5513553460798a625612031bc7bb7
ToppCell	droplet-Marrow-nan-3m-Lymphocytic-nan\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOCK10 APC BMP2K SCN3A	1.02e-05	179	34	4	87a69f9f83b8f0c028a4874acb238f2e079bf51f
ToppCell	droplet-Marrow-nan-3m-Lymphocytic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOCK10 APC BMP2K SCN3A	1.02e-05	179	34	4	dcaf2191134a586d50ebaf67dcf5b815b54a722b
ToppCell	CV-Severe-4\|Severe / Virus stimulation, Condition and Cluster	ITGAD SLC7A11 CNOT10 CD109	1.05e-05	180	34	4	cf84a01e6a33e5d27ad7be1d9069a0370b5116d1
ToppCell	droplet-Marrow-nan-3m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	APC FADS3 BMP2K SCN3A	1.05e-05	180	34	4	df60970520fba2ac0639faa54096766d07418ca4
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ANK2 SCN2A SCN3A FAM83B	1.46e-05	196	34	4	c7136b1c83bcf907eec3b02b151fa061298b6672
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Parietal_and_Temporal-6\|World / Primary Cells by Cluster	APC BPTF ANK2 SCN2A	1.55e-05	199	34	4	1b1bccf4293f11048709d15a3c892c0edf3da3d2
ToppCell	Parenchymal-10x5prime-Immune_Myeloid-Dendritic_cell-DC_activated\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	DOCK10 SCN11A SLC7A11 CNOT10	1.55e-05	199	34	4	f4ab29f99ce45a3044d2e9f356dc24d3c5e7121f
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Parietal_and_Temporal\|World / Primary Cells by Cluster	APC BPTF ANK2 SCN2A	1.55e-05	199	34	4	4bee94c116c0da5eba951cb4cea7cc9dcdd6e30f
ToppCell	severe-Lymphocytic-B_cells_2\|Lymphocytic / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	FADS3 SCN2A SCN3A	1.51e-04	136	34	3	56a7b5c2e098b4a49124d1b905257a52eb38b519
ToppCell	droplet-Lung-30m-Hematologic-myeloid-intermediate_monocyte-intermediate_monocyte_l33\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SIK2 MYO19 DUSP16	1.51e-04	136	34	3	a43b3db1754c619d328a26a2ba6af4756629a723
ToppCell	facs-Marrow-B-cells-24m-Myeloid-CD4+_macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FADS3 ITGAD SCN3A	1.90e-04	147	34	3	9d7e965fe61bd7b31e09c4b2129a5a98c36f4811
ToppCell	facs-Marrow-B-cells-24m-Myeloid-macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FADS3 ITGAD SCN3A	1.90e-04	147	34	3	38552953ff65a0fc20bee6ef57dc5885306ad18b
ToppCell	E18.5-samps-Mesenchymal-Pericyte-pericyte_B\|E18.5-samps / Age Group, Lineage, Cell class and subclass	RBM46 ANK2 IQSEC2	2.05e-04	151	34	3	8ba15ab24fe2e71df0a2a7511ca451ad2376bd91
ToppCell	367C-Lymphocytic-CD4_T-cell-Treg_cell_3\|367C / Donor, Lineage, Cell class and subclass (all cells)	ICOS CEP295NL DUSP16	2.14e-04	153	34	3	da1bff9928d8c61bb1c389d45fd897cfa4bed023
ToppCell	390C-Lymphocytic-CD4_T-cell-Treg_cell_4\|390C / Donor, Lineage, Cell class and subclass (all cells)	ELOVL3 ICOS DUSP16	2.18e-04	154	34	3	a90c4c45685eae8d21d03479cfd5a23f6ed3ca07
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC-OPC-E\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SCN1A SCN2A SCN3A	2.22e-04	155	34	3	77fdae85d36efb776db977eb424b32487ef222e4
ToppCell	droplet-Liver-LIVER_NPC-30m-Myeloid-plasmacytoid_dendritic_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FADS3 ITGAD CLCN6	2.30e-04	157	34	3	fc127e7720649e746f3d3f5c2e9e63784767106a
ToppCell	droplet-Liver-LIVER_NPC-30m-Myeloid-plasmacytoid_dendritic_cells\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FADS3 ITGAD CLCN6	2.30e-04	157	34	3	66a191cef4aa00811bb04462310d012610006f85
ToppCell	droplet-Heart-nan-24m-Mesenchymal-nan\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOCK10 RECQL FBXW10	2.39e-04	159	34	3	7ad3a91d29639b32f6264c91f401c14a35469ac0
ToppCell	PND07-Endothelial-Endothelial_lymphatic\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SCN11A SCN1A SCN3A	2.48e-04	161	34	3	133b4fadb499e842c19f573f9cf09ce08c1d4813
ToppCell	PND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SCN11A SCN1A SCN3A	2.48e-04	161	34	3	cb177ca10d848d0e25399ab5ebfcde1071fb94c2
ToppCell	PND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SCN11A SCN1A SCN3A	2.48e-04	161	34	3	9466b8658244116f8d21f2f88fb8c2d184b1bdf2
ToppCell	PND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SCN11A SCN1A SCN3A	2.53e-04	162	34	3	96c6e94a10b124a1d25dcd705ec5aaa8609c1089
ToppCell	390C-Lymphocytic-CD4_T-cell-Treg_cell_4\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	ELOVL3 ICOS DUSP16	2.57e-04	163	34	3	bca9abd02ffb2a90c8386a59f5e25126ae7b6acd
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ITGAD SCN2A SCN3A	2.62e-04	164	34	3	6fb2136168f430babfeb81ca7e151ca7a8092ec4
ToppCell	normal_Pleural_Fluid-T/NK_cells-CD4+_Th\|T/NK_cells / Location, Cell class and cell subclass	FADS3 ANK2 IQSEC2	2.62e-04	164	34	3	334f376350c9cf92611d0f75b2e18a102f4c116a
ToppCell	PND03-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SCN1A SCN3A CD109	2.67e-04	165	34	3	347b59aa625a8a960828b8620824d8ac48990e07
ToppCell	PND03-Endothelial-Endothelial_lymphatic\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SCN1A SCN3A CD109	2.67e-04	165	34	3	1890f9c33b0c5b381d57f97042da2610a093a6de
ToppCell	PND03-Endothelial-Endothelial_lymphatic-Lymphatic_EC\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SCN1A SCN3A CD109	2.67e-04	165	34	3	507c89ece0a336b8e9c65b79889a714e17ddca27
ToppCell	PND03-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SCN1A SCN3A CD109	2.67e-04	165	34	3	39a25be081a5d59c7cf107a997d352793d5025fb
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	DOCK10 ICOS DUSP16	2.76e-04	167	34	3	83969c36ac44b96afc9aa09400a99fa2b487f7ff
ToppCell	Control-NK\|Control / Disease group and Cell class	SLC7A11 IQSEC2 CD109	2.81e-04	168	34	3	683d389c8a1e791bfc773e63148115a21a6566db
ToppCell	PND01-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SCN1A SCN3A CD109	2.86e-04	169	34	3	f077e39e41fffe7672541f5b72b80faaf56c597c
ToppCell	Control-T_cells-Tregs\|Control / group, cell type (main and fine annotations)	DOCK10 ICOS DUSP16	2.86e-04	169	34	3	e1e0983f31ec81b3fad5f9c6140d17f03f81a5dc
ToppCell	PND01-Endothelial-Endothelial_lymphatic-Lymphatic_EC\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SCN1A SCN3A CD109	2.91e-04	170	34	3	35e3945d8a540a3e2cec1b559316265aaad023d1
ToppCell	PND01-Endothelial-Endothelial_lymphatic\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SCN1A SCN3A CD109	2.91e-04	170	34	3	0ea625abaa25bab93b70b7000e8f90d5c0f9a0fb
ToppCell	PND01-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SCN1A SCN3A CD109	2.91e-04	170	34	3	0b5ddc7d452db0a389927a367914f7d257703f7e
ToppCell	facs-Marrow-T-cells-3m-Myeloid-CD4+_macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ITGAD BMP2K SCN3A	2.96e-04	171	34	3	6a0fafb8fd9fc7671618eeb2bf528ce8ce86b794
ToppCell	10x_3'_v3-lymph_node_(10x_3'_v3)-myeloid-myeloid_dendritic-mature_conventional_dendritic_cell\|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	SCN11A SLC7A11 KCNJ12	2.96e-04	171	34	3	d934d68efc5739483c735dc702ccd30b07a6aa7e
ToppCell	facs-Marrow-T-cells-3m-Myeloid-macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ITGAD BMP2K SCN3A	2.96e-04	171	34	3	e02b5831768dbb1b68998b672e55c9680ab0cc86
ToppCell	facs-GAT-Fat-18m-Lymphocytic-T_cell\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCN11A RAPSN ICOS	3.01e-04	172	34	3	17a486c5d0430abb133eab9f087e2ef8b60f7d25
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Granulocytic\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK10 FBXW10 BMP2K	3.01e-04	172	34	3	3a37569a5902f3c65ff8d3912421309a8c82ee9b
ToppCell	droplet-Liver-LIVER_HEP-30m-Myeloid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOCK10 ITGAD CD109	3.01e-04	172	34	3	3f784aed340b50ddbec3f7dc0a5279180d38a2bb
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Granulocytic-Mast_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK10 FBXW10 BMP2K	3.01e-04	172	34	3	cc9d9dae290f11f8c348c78228af4e49469dc93b
ToppCell	3'_v3-lymph-node_spleen-Myeloid_Dendritic-migDC\|lymph-node_spleen / Manually curated celltypes from each tissue	SCN11A BMP2K SLC7A11	3.01e-04	172	34	3	1b24bed3cd8e3fa463c5e7cefdf9e99e639e2f84
ToppCell	facs-Lung-Endomucin-24m-Mesenchymal\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RBM46 FADS3 KCNJ12	3.06e-04	173	34	3	a37f38478473290fe35aea8684befc3bf95b161f
ToppCell	5'-Adult-LargeIntestine-Hematopoietic-Myeloid-Lymphoid_DC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ITGAD BMP2K SLC7A11	3.11e-04	174	34	3	16204ff504b7b382b4d90ca35003ad5336020e07
ToppCell	Mild-CD4+_T_Exhausted\|Mild / Disease group and Cell class	ICOS SLC7A11 CD109	3.17e-04	175	34	3	6df099f37875f2cd63502b732a2e07ebfec50e47
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	DOCK10 RECQL ICOS	3.17e-04	175	34	3	06eace2e681980456299167b48bd49bcfea5e940
ToppCell	PCW_13-14-Neuronal-Neuronal_postreplicative-neuro_neuronal_(6)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	SCN1A SCN2A SCN3A	3.38e-04	179	34	3	af0b54c9ea0b6e4210f22dbb6e88ecd3276a5f86
ToppCell	Mild-Lymphoid-T-Treg\|Mild / Condition, Lineage, Cell class and cell subclass	ICOS RHAG DUSP16	3.38e-04	179	34	3	a7c01df7623aa6cee4ed4a341545ba240194ca8b
ToppCell	COVID-19-T_cells-Tregs\|COVID-19 / group, cell type (main and fine annotations)	DOCK10 ICOS DUSP16	3.50e-04	181	34	3	534659cf754326c6a73c0daa30e9d610612a0292
ToppCell	Epithelial-lung_neuroendocrine_cell_(PNEC)\|World / Lineage, Cell type, age group and donor	ANK2 SCN2A SCN3A	3.55e-04	182	34	3	57bf4ffb304324e2e392e196336a530d9f78fe0d
ToppCell	facs-Lung-Endomucin-24m-Mesenchymal-pericyte_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RBM46 FADS3 KCNJ12	3.55e-04	182	34	3	be9c312a44868d4ee266a64d066feb8c5bce5687
ToppCell	facs-Lung-Endomucin-24m-Mesenchymal-Pericyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RBM46 FADS3 KCNJ12	3.55e-04	182	34	3	74dbb706bcaa0f8c922bf3b0424bce5bb27167fa
ToppCell	cellseq-Immune-Immune_Myeloid-Myeloid_Dendritic-maDC\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	DOCK10 ITGAD SLC7A11	3.61e-04	183	34	3	e01dacb08a9c36cf09c0b6764ce032a7232d4cdc
ToppCell	3'-Pediatric_IBD-SmallIntestine-Hematopoietic-Myeloid-Lymphoid_DC\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SCN11A BMP2K SLC7A11	3.61e-04	183	34	3	9ca4954faaba50466c35121d6765895e955178aa
ToppCell	droplet-Thymus-nan-3m-Lymphocytic-Double_negative_Thymocyte,_DN4_(Cd8-,_Cd4-),_some_undergoing_VDJ_recombination_\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RAPSN ICOS ANK2	3.61e-04	183	34	3	a0a3e4d07ac73dbbb1e019fd11e88ccffe6cf2ca
ToppCell	Control-Epithelial_cells-Airway_mucous\|Control / group, cell type (main and fine annotations)	SLC7A11 SCN2A SCN3A	3.61e-04	183	34	3	15d24a4fb1ffe6cbafbd54fcd7dde9ddcfbe03b2
ToppCell	343B-Fibroblasts-Fibroblast-E\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	MYO19 SCN2A CD109	3.73e-04	185	34	3	02cbf492bc40abebaa93a3a208888afae72fbe06
ToppCell	343B-Fibroblasts-Fibroblast-E-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	MYO19 SCN2A CD109	3.73e-04	185	34	3	1b8e3ddb91797f84e4b15d2457b0c008e5be50db
ToppCell	CV-Moderate-7\|CV / Virus stimulation, Condition and Cluster	DOCK10 ITGAD SLC7A11	3.79e-04	186	34	3	8571956890fc9894d766ba294a28e376b4aba428
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_T/NK\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK10 ICOS DUSP16	3.79e-04	186	34	3	9d576dce2c5deefef1adda16c6da7055c8d57f8f
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_T/NK-T_Cell-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK10 ICOS DUSP16	3.79e-04	186	34	3	bd3bd022b575d9b0ef90d50a5cb874085a827b77
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_T/NK-T_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK10 ICOS DUSP16	3.79e-04	186	34	3	924cc357b4c4ce8e9b05773bdab544f0b65474cc
ToppCell	Fetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ANK2 SCN2A SCN3A	3.79e-04	186	34	3	b45cce768e4bf91da194fd9660cab7520dfb15ac
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SCN2A SCN3A FAM83B	3.85e-04	187	34	3	77886f99c229610abd28c4c370d2c7d1536c9782
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SCN2A SCN3A FAM83B	3.85e-04	187	34	3	f124d2c699b717b7c02a1a70493f515b83dc2f4c
ToppCell	COVID-19-kidney-DCT\|COVID-19 / Disease (COVID-19 only), tissue and cell type	SCN2A SCN3A FAM83B	3.91e-04	188	34	3	1d56cd409793f05cca20757ab26e91f1a1ee67b5
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2-D175\|Adult / Lineage, Cell type, age group and donor	SLC7A11 SCN1A DUSP16	3.91e-04	188	34	3	ec38def1fdbb34ed9b30244806975bd5a4370164
ToppCell	Fetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ANK2 SCN2A SCN3A	3.91e-04	188	34	3	c4c3b21ab723b0e9beff9ec84f8d68485f771528
ToppCell	21-Trachea-Epithelial-Neuroendocrine\|Trachea / Age, Tissue, Lineage and Cell class	ANK2 SCN2A SCN3A	3.91e-04	188	34	3	e78d4f7a5d28c77503cb041ff585d13df4c88bd2
ToppCell	COVID-19-kidney-DCT\|kidney / Disease (COVID-19 only), tissue and cell type	SCN2A SCN3A FAM83B	3.91e-04	188	34	3	df1fd0819d301679f3c9ea404e942e39095912eb
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SCN2A SCN3A FAM83B	3.97e-04	189	34	3	e32172ad09e93f6ac6ea2b92145b2b73003f7970
ToppCell	3'-Broncho-tracheal-Epithelial-Neuro-endocrine/ionocytic-lung_neuroendocrine_cell-Neuroendocrine\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ANK2 SCN2A SCN3A	4.03e-04	190	34	3	40d8b3403f4e38436b961cd3a2e69826cbae3042
ToppCell	normal_Lymph_Node-Myeloid_cells-Activated_DCs\|normal_Lymph_Node / Location, Cell class and cell subclass	SCN11A BMP2K SLC7A11	4.03e-04	190	34	3	15978ddd37b521343f88b62dad1643077fc22b2b
ToppCell	3'-Broncho-tracheal-Epithelial-Neuro-endocrine/ionocytic-lung_neuroendocrine_cell-Neuroendocrine-Neuroendocrine_L.0.7.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ANK2 SCN2A SCN3A	4.03e-04	190	34	3	f6cbf6d292f488ada5f7581e1dceba6198b933d1
ToppCell	3'-Broncho-tracheal-Epithelial-Neuro-endocrine/ionocytic-lung_neuroendocrine_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ANK2 SCN2A SCN3A	4.03e-04	190	34	3	a9a705455019e28d655636de73b07540798f82e6
ToppCell	COVID-19-kidney-CNT\|COVID-19 / Disease (COVID-19 only), tissue and cell type	SCN2A SCN3A FAM83B	4.15e-04	192	34	3	760c6b9628de9693034b00c5025c5c4df94bb2e8
ToppCell	droplet-Spleen-SPLEEN-1m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCN11A FADS3 RHAG	4.15e-04	192	34	3	a94f47a664a3c9d1b0250269674453309ab4bf95
ToppCell	10x_3'_v3-bone_marrow_(10x_3'_v3)-hematologic-erythrocytic-erythrocyte\|bone_marrow_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	BMP2K SLC7A11 RHAG	4.22e-04	193	34	3	305e15ee467826ee08b2617c69f250ad39c11b19
ToppCell	10x_3'_v3-bone_marrow_(10x_3'_v3)-hematologic-erythrocytic\|bone_marrow_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	BMP2K SLC7A11 RHAG	4.22e-04	193	34	3	dd376664906caccc9c2065f8e7a364509e18a5cc
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Stem-like-NPC-like-NPC-like_neural-E\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	APC FBXW10 SCN3A	4.28e-04	194	34	3	b111d10c99d7ff7eb261cd7786cd9d9a549049b1
ToppCell	severe-B_cell\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	APC SCN2A SCN3A	4.28e-04	194	34	3	2fee6083fb56b16d1f04fd0b92ec622fd26ba3fa
ToppCell	Parenchymal-10x5prime-Epithelial-Epi_airway_neuro-secretory\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	ANK2 SCN2A SCN3A	4.28e-04	194	34	3	d024cd75a97f048257e49cee9190fb2e79202ee2
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SCN2A SCN3A FAM83B	4.28e-04	194	34	3	46070fbb0ee0eb9e1801c43b73a15707471056dc
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SCN2A SCN3A FAM83B	4.28e-04	194	34	3	abacb6a8d7a9003f2f6c2be0305507f1c1c50347
ToppCell	COVID-19-kidney-Proliferating_T_cell\|kidney / Disease (COVID-19 only), tissue and cell type	DOCK10 ICOS RHAG	4.35e-04	195	34	3	7e05e56f8d0a7a052830c7db12b10dace7d10760
ToppCell	severe-B_cell\|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	APC SCN2A SCN3A	4.35e-04	195	34	3	0fc3c605609c9e6bdea15d73c45def2188ae5fb1
ToppCell	IPF-Lymphoid-T\|Lymphoid / Disease state, Lineage and Cell class	DOCK10 ICOS DUSP16	4.41e-04	196	34	3	6e70c48a63d9673eb16b0847c1bd88eecc2f7a3c
ToppCell	Basal_cells-Myositis-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	HORMAD1 FAM83B CD109	4.41e-04	196	34	3	3b66f3a79b3f2ebacb4ad646f179e505ab38d6f0
ToppCell	COPD-Lymphoid-T\|Lymphoid / Disease state, Lineage and Cell class	DOCK10 ICOS DUSP16	4.41e-04	196	34	3	c9bdd505c3ab380ed7b272aa518df31a0a706a06
ToppCell	Tracheal-10x3prime_v2-Immune_Lymphocytic-T-T_CD4-CD4_naive/CM\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	DOCK10 ICOS RHAG	4.48e-04	197	34	3	1c78bd52b94a9466459a645ac9bd14bac22c54bd
ToppCell	LPS_only-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS_only / Treatment groups by lineage, cell group, cell type	FADS3 BMP2K FAM83B	4.48e-04	197	34	3	6b6504c47c309bac4f790e2f372d454bbdea49e8
ToppCell	3'-GW_trimst-1-LargeIntestine-Neuronal-neurons_A-Branch_A2_(IPAN/IN)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ANK2 SCN2A SCN3A	4.48e-04	197	34	3	27c044833e471a312a572e0b1c83e4bc8a36e896
ToppCell	Bronchial-NucSeq-Immune_Myeloid-Dendritic_cell-DC_activated\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SCN11A BMP2K SLC7A11	4.48e-04	197	34	3	68d8546dfe7dffd017756a11d3333061f576d0ef
Drug	Zonisamide	SCN11A SCN1A SCN2A SCN3A	9.73e-09	17	34	4	DB00909
Drug	APETx1, Anthopleura elegantissima	SCN10A SCN2A SCN3A	6.07e-08	6	34	3	ctd:C475726
Drug	fenpropathrin	SCN10A SCN2A SCN3A	6.07e-08	6	34	3	ctd:C044267
Drug	2,3,5,6-tetrafluoro-4-methylbenzyl (Z)-(1RS)-cis-3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropanecarboxylate	SCN10A SCN2A SCN3A	1.70e-07	8	34	3	ctd:C489827
Drug	saxitoxin	SCN10A ANK2 SCN2A SCN3A	2.63e-06	65	34	4	CID000037165
Drug	Sodium	SCN10A SCN11A SCN2A SCN3A	7.35e-06	84	34	4	ctd:D012964
Drug	fluphenazine dihydrochloride; Up 200; 10uM; MCF7; HT_HG-U133A	SCN10A SCN11A FADS3 CLCN6 SLC7A11	7.92e-06	186	34	5	5597_UP
Drug	Methylhydantoin-5-(L) [40856-73-3]; Down 200; 35uM; MCF7; HT_HG-U133A	APC FADS3 BMP2K SLC7A11 IQSEC2	9.47e-06	193	34	5	3378_DN
Drug	Crotamiton [483-63-6]; Down 200; 19.6uM; PC3; HT_HG-U133A	APC ICOS BMP2K SLC7A11 IQSEC2	1.02e-05	196	34	5	4628_DN
Drug	nordihydroguaiaretic acid; Up 200; 1uM; MCF7; HT_HG-U133A_EA	RAPSN FADS3 BMP2K SLC7A11 IQSEC2	1.05e-05	197	34	5	1003_UP
Drug	Carbimazole [22232-54-8]; Up 200; 21.4uM; MCF7; HT_HG-U133A	APC ANK2 CLCN6 SLC7A11 RHAG	1.05e-05	197	34	5	3299_UP
Drug	cyfluthrin	SCN10A SCN2A SCN3A	1.08e-05	29	34	3	ctd:C052570
Drug	Prazosin hydrochloride [19237-84-4]; Down 200; 9.6uM; MCF7; HT_HG-U133A	APC RAPSN FADS3 CLCN6 BMP2K	1.10e-05	199	34	5	6475_DN
Drug	tocainide	SCN10A ANK2 SCN3A	1.20e-05	30	34	3	CID000038945
Drug	APETx2 protein, Anthopleura elegantissima	SCN10A SCN2A	1.30e-05	4	34	2	ctd:C501880
Drug	benzocaine	SCN10A SCN2A SCN3A	2.28e-05	37	34	3	CID000002337
Drug	Cocaine	SCN10A SCN11A	6.03e-05	8	34	2	DB00907
Drug	cypermethrin	SCN10A APC SLC7A11 SCN2A SCN3A	6.03e-05	284	34	5	ctd:C017160
Drug	1-phenylethanol	SCN10A APC SCN11A	6.03e-05	51	34	3	CID000007409
Drug	decamethrin	SCN10A SCN1A SCN2A SCN3A	6.48e-05	146	34	4	ctd:C017180
Drug	mexiletine	SCN10A ANK2 SCN3A	1.31e-04	66	34	3	CID000004178
Drug	Tetrandrine [518-34-3]; Up 200; 6.4uM; MCF7; HT_HG-U133A	SIK2 APC CLCN6 SLC7A11	1.34e-04	176	34	4	7178_UP
Drug	Thiostrepton [1393-48-2]; Down 200; 2.4uM; HL60; HT_HG-U133A	SIK2 DOCK10 BPTF TUBGCP3	1.36e-04	177	34	4	2462_DN
Drug	carbamazepine	SCN10A SLC13A2 SCN2A SCN3A	1.42e-04	179	34	4	CID000002554
Drug	Zuclopenthixol hydrochloride [633-59-0]; Up 200; 9.2uM; MCF7; HT_HG-U133A	APC FADS3 BMP2K SLC7A11	1.46e-04	180	34	4	7356_UP
Drug	17-AAG; Up 200; 1uM; MCF7; HT_HG-U133A_EA	FADS3 CLCN6 BMP2K SLC7A11	1.62e-04	185	34	4	831_UP
Drug	17-AAG; Up 200; 1uM; MCF7; HT_HG-U133A_EA	RAPSN CLCN6 BMP2K SLC7A11	1.62e-04	185	34	4	986_UP
Drug	flecainide	SCN10A SCN11A SCN3A	1.62e-04	71	34	3	CID000003355
Drug	fluphenazine dihydrochloride; Up 200; 10uM; MCF7; HT_HG-U133A	APC CLCN6 SLC7A11 IQSEC2	1.69e-04	187	34	4	1662_UP
Drug	17-AAG; Up 200; 1uM; MCF7; HT_HG-U133A	RAPSN SLC7A11 SCN1A IQSEC2	1.72e-04	188	34	4	6926_UP
Drug	Chlorpromazine hydrochloride [69-09-0]; Up 200; 11.2uM; MCF7; HT_HG-U133A	SCN10A FADS3 ANK2 SLC7A11	1.72e-04	188	34	4	5493_UP
Drug	2-propylpentanoic acid; Up 200; 500uM; PC3; HT_HG-U133A	APC SCN11A FADS3 ICOS	1.76e-04	189	34	4	4464_UP
Drug	procainamide	SCN10A BPTF SCN11A SCN3A	1.79e-04	190	34	4	CID000004913
Drug	1, 3-diallylurea	SCN10A RHAG SCN3A	1.83e-04	74	34	3	CID000074537
Drug	Carbarsone [121-59-5]; Down 200; 15.4uM; MCF7; HT_HG-U133A	APC FADS3 SLC7A11 TUBGCP3	1.86e-04	192	34	4	4110_DN
Drug	Thalidomide [50-35-1]; Down 200; 15.4uM; MCF7; HT_HG-U133A	APC BMP2K IQSEC2 TUBGCP3	1.86e-04	192	34	4	5990_DN
Drug	Avermectin B1 [71751-41-2]; Up 200; 4.8uM; MCF7; HT_HG-U133A	APC RAPSN BMP2K SLC7A11	1.86e-04	192	34	4	7218_UP
Drug	prochlorperazine dimaleate salt; Up 200; 10uM; MCF7; HT_HG-U133A	SCN10A APC FADS3 SLC7A11	1.86e-04	192	34	4	5575_UP
Drug	Lovastatin [75330-75-5]; Up 200; 9.8uM; MCF7; HT_HG-U133A	SCN10A SLC7A11 IQSEC2 TUBGCP3	1.90e-04	193	34	4	4978_UP
Drug	Isotretinoin [4759-48-2]; Up 200; 13.4uM; PC3; HT_HG-U133A	APC ICOS CLCN6 SLC7A11	1.90e-04	193	34	4	7315_UP
Drug	Phenylpropanolamine hydrochloride [154-41-6]; Down 200; 21.4uM; PC3; HT_HG-U133A	SCN10A APC RAPSN IQSEC2	1.90e-04	193	34	4	6699_DN
Drug	PF-01378883-00 [351320-41-7]; Up 200; 10uM; PC3; HT_HG-U133A	SCN10A APC RAPSN CLCN6	1.94e-04	194	34	4	6368_UP
Drug	5252917; Up 200; 14uM; MCF7; HT_HG-U133A_EA	FADS3 CLCN6 BMP2K SLC7A11	1.94e-04	194	34	4	828_UP
Drug	1,2-Dsmgg	SCN10A SCN11A	1.95e-04	14	34	2	CID000193820
Drug	Neostigmine bromide [114-80-7]; Up 200; 13.2uM; MCF7; HT_HG-U133A	SCN10A DOCK10 FADS3 CLCN6	1.98e-04	195	34	4	3294_UP
Drug	5248896; Up 200; 11uM; MCF7; HT_HG-U133A_EA	SCN10A FADS3 SLC7A11 TUBGCP3	1.98e-04	195	34	4	838_UP
Drug	Miconazole [22916-47-8]; Up 200; 9.6uM; MCF7; HT_HG-U133A	SCN10A FADS3 CLCN6 SLC7A11	1.98e-04	195	34	4	4960_UP
Drug	Rapamycin; Down 200; 0.1uM; HL60; HT_HG-U133A	SIK2 APC CLCN6 SLC7A11	1.98e-04	195	34	4	1162_DN
Drug	ICI182,780; Up 200; 1uM; MCF7; HT_HG-U133A	SCN10A APC SLC13A2 BMP2K	2.02e-04	196	34	4	5926_UP
Drug	Eburnamonine (-) [4880-88-0]; Up 200; 13.6uM; MCF7; HT_HG-U133A	APC BMP2K SLC7A11 IQSEC2	2.02e-04	196	34	4	2781_UP
Drug	ST021200; Down 200; 10uM; PC3; HT_HG-U133A	APC FADS3 CLCN6 BMP2K	2.02e-04	196	34	4	7559_DN
Drug	Glibenclamide [10238-21-8]; Up 200; 8uM; PC3; HT_HG-U133A	SCN10A APC SCN1A RHAG	2.02e-04	196	34	4	5849_UP
Drug	Buspirone hydrochloride [33386-08-2]; Up 200; 9.4uM; MCF7; HT_HG-U133A	SCN10A APC BMP2K TUBGCP3	2.02e-04	196	34	4	5343_UP
Drug	Tinidazole [19387-91-8]; Up 200; 16.2uM; MCF7; HT_HG-U133A	APC SCN11A ICOS RHAG	2.02e-04	196	34	4	4370_UP
Drug	Sulfapyridine [144-83-2]; Up 200; 16uM; MCF7; HT_HG-U133A	SCN10A APC SCN11A CLCN6	2.02e-04	196	34	4	6101_UP
Drug	Vidarabine [5536-17-4]; Up 200; 15uM; HL60; HT_HG-U133A	RAPSN FADS3 ANK2 IQSEC2	2.02e-04	196	34	4	2706_UP
Drug	AG-013608 [351320-38-2]; Up 200; 10uM; MCF7; HT_HG-U133A	SIK2 SCN11A SLC7A11 SCN3A	2.02e-04	196	34	4	6435_UP
Drug	prochlorperazine dimaleate salt; Down 200; 10uM; PC3; HT_HG-U133A	SCN10A APC IQSEC2 TUBGCP3	2.02e-04	196	34	4	4439_DN
Drug	Benzylpenicillin sodium [69-57-8]; Up 200; 11.2uM; MCF7; HT_HG-U133A	APC SCN11A FADS3 SCN1A	2.06e-04	197	34	4	3577_UP
Drug	Estriol [50-27-1]; Up 200; 13.8uM; PC3; HT_HG-U133A	SCN10A FADS3 CLCN6 RHAG	2.06e-04	197	34	4	5866_UP
Drug	Sulfamethizole [144-82-1]; Up 200; 14.8uM; MCF7; HT_HG-U133A	SCN10A SCN11A ANK2 CLCN6	2.06e-04	197	34	4	6099_UP
Drug	Diphenylpyraline hydrochloride [132-18-3]; Down 200; 12.6uM; MCF7; HT_HG-U133A	APC ICOS CLCN6 BMP2K	2.06e-04	197	34	4	6061_DN
Drug	Melatonin [73-31-4]; Up 200; 17.2uM; MCF7; HT_HG-U133A	DOCK10 APC ICOS CLCN6	2.06e-04	197	34	4	3293_UP
Drug	Trimethoprim [738-70-5]; Down 200; 13.8uM; MCF7; HT_HG-U133A	SIK2 APC CLCN6 BMP2K	2.06e-04	197	34	4	2307_DN
Drug	Clonidine hydrochloride [4205-91-8]; Up 200; 15uM; PC3; HT_HG-U133A	APC SCN11A ANK2 BMP2K	2.06e-04	197	34	4	4478_UP
Drug	Atropine sulfate monohydrate [5908-99-6]; Up 200; 5.8uM; MCF7; HT_HG-U133A	SCN10A DOCK10 BMP2K IQSEC2	2.06e-04	197	34	4	2761_UP
Drug	Alclometasone dipropionate [667634-13-2]; Down 200; 7.6uM; MCF7; HT_HG-U133A	SIK2 RAPSN BMP2K IQSEC2	2.06e-04	197	34	4	6094_DN
Drug	Tobramycin [32986-56-4]; Down 200; 8.6uM; PC3; HT_HG-U133A	DOCK10 APC RAPSN IQSEC2	2.10e-04	198	34	4	4081_DN
Drug	15(S)-15-methyl Prostaglandin E2; Down 200; 10uM; MCF7; HT_HG-U133A	SIK2 APC CLCN6 SLC7A11	2.10e-04	198	34	4	7521_DN
Drug	S(+)-Terguride [37686-84-3]; Down 200; 11.8uM; MCF7; HT_HG-U133A	RAPSN FADS3 CLCN6 IQSEC2	2.10e-04	198	34	4	6459_DN
Drug	wortmannin from Penicillium funiculosum; Down 200; 0.01uM; HL60; HT_HG-U133A	SIK2 APC BMP2K SLC7A11	2.10e-04	198	34	4	1184_DN
Drug	Benzthiazide [91-33-8]; Up 200; 9.2uM; MCF7; HT_HG-U133A	RAPSN FADS3 CLCN6 BMP2K	2.10e-04	198	34	4	4952_UP
Drug	Pepstatin A [26305-03-3]; Down 200; 5.8uM; MCF7; HT_HG-U133A	APC CLCN6 SLC7A11 IQSEC2	2.10e-04	198	34	4	3264_DN
Drug	Paroxetine maleate [64006-44-6]; Up 200; 1uM; MCF7; HT_HG-U133A	SCN10A APC ICOS SLC13A2	2.10e-04	198	34	4	3904_UP
Drug	SC 19220; Down 200; 10uM; MCF7; HT_HG-U133A	RECQL FADS3 BMP2K SLC7A11	2.14e-04	199	34	4	7090_DN
Drug	2-Chloropyrazine [14508-49-7]; Up 200; 35uM; MCF7; HT_HG-U133A	APC CLCN6 SLC7A11 TUBGCP3	2.14e-04	199	34	4	3570_UP
Drug	Cefixime [79350-37-1]; Down 200; 8.8uM; MCF7; HT_HG-U133A	SIK2 APC CLCN6 BMP2K	2.14e-04	199	34	4	4390_DN
Drug	Epiandrosterone [481-29-8]; Up 200; 13.8uM; MCF7; HT_HG-U133A	SCN10A DOCK10 CLCN6 SLC7A11	2.14e-04	199	34	4	5687_UP
Drug	(cis-) Nanophine [5072-45-7]; Up 200; 26.8uM; PC3; HT_HG-U133A	SCN11A ICOS CLCN6 SCN1A	2.14e-04	199	34	4	4543_UP
Drug	Retrorsine [480-54-6]; Up 200; 11.4uM; MCF7; HT_HG-U133A	APC SLC7A11 RHAG IQSEC2	2.14e-04	199	34	4	4946_UP
Drug	estradiol, USP; Up 200; 0.1uM; MCF7; HT_HG-U133A	APC BMP2K SLC7A11 TUBGCP3	2.14e-04	199	34	4	1633_UP
Drug	minocycline; Up 200; 10.5uM; MCF7; HT_HG-U133A_EA	RECQL SLC7A11 MYO19 TUBGCP3	2.14e-04	199	34	4	1135_UP
Drug	Gliclazide [21187-98-4]; Up 200; 12.4uM; MCF7; HT_HG-U133A	DOCK10 SCN11A RHAG IQSEC2	2.14e-04	199	34	4	2870_UP
Drug	Amrinone [60719-84-8]; Down 200; 21.4uM; MCF7; HT_HG-U133A	APC FADS3 BMP2K SLC7A11	2.18e-04	200	34	4	3465_DN
Drug	Minocycline hydrochloride [13614-98-7]; Up 200; 8uM; MCF7; HT_HG-U133A	APC FADS3 SLC7A11 IQSEC2	2.18e-04	200	34	4	7436_UP
Drug	apholate	SCN10A SCN11A	2.25e-04	15	34	2	CID000005845
Drug	PD 150606	SCN2A SCN3A	2.90e-04	17	34	2	ctd:C100442
Drug	Scorpion Venoms	SCN2A SCN3A	3.26e-04	18	34	2	ctd:D012604
Drug	AC1NRC8M	SCN2A SCN3A	3.64e-04	19	34	2	CID005288877
Drug	diprafenone	SCN10A SCN3A	3.64e-04	19	34	2	CID000071249
Drug	fenvalerate	SCN10A SCN2A SCN3A	4.08e-04	97	34	3	ctd:C017690
Drug	sodium	SCN10A ANK2 SLC13A2 SLC7A11 SCN2A SCN3A KCNJ12	4.15e-04	944	34	7	CID000000923
Drug	methanethiosulfonate	SLC13A2 SLC7A11 KCNJ12	4.86e-04	103	34	3	CID004188587
Disease	generalized epilepsy with febrile seizures plus 2 (implicated_via_orthology)	SCN10A SCN11A SCN1A SCN2A SCN3A	3.75e-13	10	34	5	DOID:0111294 (implicated_via_orthology)
Disease	Dravet syndrome (implicated_via_orthology)	SCN10A SCN11A SCN1A SCN2A SCN3A	3.75e-13	10	34	5	DOID:0080422 (implicated_via_orthology)
Disease	generalized epilepsy with febrile seizures plus (implicated_via_orthology)	SCN10A SCN11A SCN1A SCN2A SCN3A	1.18e-12	12	34	5	DOID:0060170 (implicated_via_orthology)
Disease	epilepsy (implicated_via_orthology)	SCN10A SCN11A ANK2 SLC13A2 SCN1A SCN2A SCN3A	6.54e-10	163	34	7	DOID:1826 (implicated_via_orthology)
Disease	anxiety disorder (implicated_via_orthology)	SCN1A SCN2A SCN3A	2.12e-06	22	34	3	DOID:2030 (implicated_via_orthology)
Disease	PAROXYSMAL EXTREME PAIN DISORDER	SCN10A SCN11A	3.86e-06	3	34	2	C1833661
Disease	Primary Erythermalgia	SCN10A SCN11A	3.86e-06	3	34	2	C0014805
Disease	Neurodevelopmental Disorders	ANK2 SCN1A SCN2A IQSEC2	3.99e-06	93	34	4	C1535926
Disease	level of Phosphatidylcholine (16:0_18:0) in blood serum	RAPSN FADS3	1.93e-05	6	34	2	OBA_2045069
Disease	level of Phosphatidylcholine (16:1_20:4) in blood serum	RAPSN FADS3	1.93e-05	6	34	2	OBA_2045084
Disease	Hereditary Sensory Autonomic Neuropathy, Type 5	SCN10A SCN11A	2.70e-05	7	34	2	C0020075
Disease	level of Phosphatidylcholine (O-18:2_18:1) in blood serum	RAPSN FADS3	2.70e-05	7	34	2	OBA_2045133
Disease	Seizure, Febrile, Simple	SCN1A SCN2A	2.70e-05	7	34	2	C0149886
Disease	Seizure, Febrile, Complex	SCN1A SCN2A	2.70e-05	7	34	2	C0751057
Disease	lysophosphatidylcholine 22:4 measurement	RAPSN FADS3	2.70e-05	7	34	2	EFO_0021461
Disease	phosphatidylcholine 35:5 measurement	RAPSN FADS3	2.70e-05	7	34	2	EFO_0021472
Disease	Congenital Pain Insensitivity	SCN10A SCN11A	2.70e-05	7	34	2	C0002768
Disease	level of Phosphatidylethanolamine (O-18:1_18:2) in blood serum	RAPSN FADS3	3.59e-05	8	34	2	OBA_2045147
Disease	phosphatidylcholine 39:5 measurement	RAPSN FADS3	4.62e-05	9	34	2	EFO_0021476
Disease	level of Phosphatidylcholine (18:2_20:1) in blood serum	RAPSN FADS3	4.62e-05	9	34	2	OBA_2045107
Disease	level of Phosphatidylcholine (O-18:0_20:4) in blood serum	RAPSN FADS3	4.62e-05	9	34	2	OBA_2045127
Disease	level of Phosphatidylcholine (O-18:1_18:2) in blood serum	RAPSN FADS3	4.62e-05	9	34	2	OBA_2045129
Disease	level of Phosphatidylcholine (O-18:1_20:3) in blood serum	RAPSN FADS3	4.62e-05	9	34	2	OBA_2045130
Disease	Febrile Convulsions	SCN1A SCN2A	4.62e-05	9	34	2	C0009952
Disease	Generalized Epilepsy with Febrile Seizures Plus	SCN1A SCN2A	4.62e-05	9	34	2	C3502809
Disease	level of Phosphatidylcholine (16:0_20:5) in blood serum	RAPSN FADS3	4.62e-05	9	34	2	OBA_2045077
Disease	level of Phosphatidylcholine (18:0_20:5) in blood serum	RAPSN FADS3	4.62e-05	9	34	2	OBA_2045095
Disease	level of Phosphatidylethanolamine (O-18:1_20:4) in blood serum	RAPSN FADS3	5.77e-05	10	34	2	OBA_2045148
Disease	cholesteryl ester 22:4 measurement	RAPSN FADS3	5.77e-05	10	34	2	EFO_0021443
Disease	cholesteryl ester 22:5 measurement	RAPSN FADS3	5.77e-05	10	34	2	EFO_0021444
Disease	level of Phosphatidylcholine (O-16:1_20:4) in blood serum	RAPSN FADS3	7.04e-05	11	34	2	OBA_2045123
Disease	lysophosphatidylcholine 20:2 measurement	RAPSN FADS3	7.04e-05	11	34	2	EFO_0021458
Disease	cholesteryl ester 20:2 measurement	RAPSN FADS3	8.44e-05	12	34	2	EFO_0021440
Disease	level of Phosphatidylcholine (O-16:0_20:4) in blood serum	RAPSN FADS3	9.97e-05	13	34	2	OBA_2045116
Disease	Infantile Severe Myoclonic Epilepsy	SCN1A SCN2A	9.97e-05	13	34	2	C0751122
Disease	level of Phosphatidylcholine (16:0_18:3) in blood serum	RAPSN FADS3	9.97e-05	13	34	2	OBA_2045072
Disease	level of Phosphatidylcholine (18:1_20:2) in blood serum	RAPSN FADS3	1.16e-04	14	34	2	OBA_2045102
Disease	diacylglycerol 38:4 measurement	RAPSN FADS3	1.16e-04	14	34	2	EFO_0020066
Disease	Epilepsy, Cryptogenic	SCN1A SCN2A IQSEC2	1.16e-04	82	34	3	C0086237
Disease	Awakening Epilepsy	SCN1A SCN2A IQSEC2	1.16e-04	82	34	3	C0751111
Disease	Aura	SCN1A SCN2A IQSEC2	1.16e-04	82	34	3	C0236018
Disease	MMR-related febrile seizures	SCN1A SCN2A	1.34e-04	15	34	2	EFO_0006519
Disease	level of Phosphatidylcholine (O-18:1_20:4) in blood serum	RAPSN FADS3	1.34e-04	15	34	2	OBA_2045131
Disease	cis/trans-18:2 fatty acid measurement, trans fatty acid measurement	RAPSN FADS3	1.34e-04	15	34	2	EFO_0006821, EFO_0006824
Disease	oleoyl-arachidonoyl-glycerol (18:1/20:4) [2] measurement	RAPSN FADS3	1.34e-04	15	34	2	EFO_0800508
Disease	P wave duration	SCN10A RAPSN	1.34e-04	15	34	2	EFO_0005094
Disease	Romano-Ward Syndrome	SCN10A ANK2	1.53e-04	16	34	2	C0035828
Disease	Early infantile epileptic encephalopathy with suppression bursts	SCN1A SCN2A	1.53e-04	16	34	2	C0393706
Disease	phosphatidylcholine 36:4 measurement	RAPSN FADS3	1.95e-04	18	34	2	EFO_0010382
Disease	Febrile seizure (within the age range of 3 months to 6 years)	SCN1A SCN2A	1.95e-04	18	34	2	HP_0002373
Disease	level of Phosphatidylcholine (20:4_0:0) in blood serum	RAPSN FADS3	1.95e-04	18	34	2	OBA_2045110
Disease	level of Phosphatidylcholine (16:0_22:5) in blood serum	RAPSN FADS3	1.95e-04	18	34	2	OBA_2045079
Disease	level of Sterol ester (27:1/20:3) in blood serum	RAPSN FADS3	2.18e-04	19	34	2	OBA_2045199
Disease	diacylglycerol 38:5 measurement	RAPSN FADS3	2.18e-04	19	34	2	EFO_0020067
Disease	diacylglycerol 38:3 measurement	RAPSN FADS3	2.18e-04	19	34	2	EFO_0020065
Disease	level of Phosphatidylcholine (18:1_20:4) in blood serum	RAPSN FADS3	2.67e-04	21	34	2	OBA_2045104
Disease	level of Phosphatidylinositol (18:0_18:2) in blood serum	RAPSN FADS3	2.67e-04	21	34	2	OBA_2045156
Disease	level of Phosphatidylcholine (16:0_20:4) in blood serum	RAPSN FADS3	2.67e-04	21	34	2	OBA_2045076
Disease	Epilepsy	SCN1A SCN2A IQSEC2	2.70e-04	109	34	3	C0014544
Disease	level of Phosphatidylinositol (18:0_20:4) in blood serum	RAPSN FADS3	3.21e-04	23	34	2	OBA_2045158
Disease	phosphatidylserines measurement	RAPSN FADS3	3.21e-04	23	34	2	EFO_0020049
Disease	Brugada Syndrome (disorder)	SCN10A ANK2	3.50e-04	24	34	2	C1142166
Disease	alpha-linolenic acid measurement	RAPSN FADS3	3.80e-04	25	34	2	EFO_0007759
Disease	lysophosphatidylethanolamine 18:2 measurement	RAPSN FADS3	4.12e-04	26	34	2	EFO_0010369
Disease	level of Phosphatidylcholine (17:0_20:4) in blood serum	RAPSN FADS3	4.12e-04	26	34	2	OBA_2045087
Disease	cholesteryl ester 14:0 measurement	RAPSN SCN3A	4.44e-04	27	34	2	EFO_0010340
Disease	docosapentaenoic acid measurement	RAPSN FADS3	4.44e-04	27	34	2	EFO_0006809
Disease	level of Phosphatidylethanolamine (18:0_18:2) in blood serum	RAPSN FADS3	4.78e-04	28	34	2	OBA_2045139
Disease	lysophosphatidylethanolamine 20:4 measurement	RAPSN FADS3	5.13e-04	29	34	2	EFO_0010370
Disease	eicosapentaenoic acid measurement	RAPSN FADS3	5.87e-04	31	34	2	EFO_0007760
Disease	level of Sterol ester (27:1/20:4) in blood serum	RAPSN FADS3	5.87e-04	31	34	2	OBA_2045198
Disease	level of Phosphatidylcholine (18:0_20:4) in blood serum	RAPSN FADS3	5.87e-04	31	34	2	OBA_2045094
Disease	lysophosphatidylcholine 20:4 measurement	RAPSN FADS3	6.25e-04	32	34	2	EFO_0010363
Disease	cholesteryl ester 22:6 measurement	RAPSN FADS3	6.25e-04	32	34	2	EFO_0010350
Disease	social communication impairment	SCN10A SCN11A	6.25e-04	32	34	2	EFO_0005427
Disease	phosphatidylcholine 38:5 measurement	RAPSN FADS3	6.65e-04	33	34	2	EFO_0010387
Disease	phosphatidylcholine 38:2 measurement	RAPSN FADS3	7.49e-04	35	34	2	EFO_0010384
Disease	sleep duration	RAPSN SLC7A11 SCN1A FAM83B	7.73e-04	362	34	4	EFO_0005271
Disease	cholesteryl ester 16:0 measurement	RAPSN FADS3	7.92e-04	36	34	2	EFO_0010341
Disease	triacylglycerol 56:8 measurement	RAPSN FADS3	7.92e-04	36	34	2	EFO_0010435
Disease	age at first sexual intercourse measurement	APC BPTF SCN2A KCNJ12	9.53e-04	383	34	4	EFO_0009749
Disease	cholesteryl ester 18:3 measurement	RAPSN FADS3	9.78e-04	40	34	2	EFO_0010346
Disease	lysophosphatidylethanolamine measurement	RAPSN FADS3	1.03e-03	41	34	2	EFO_0010225
Disease	triacylglycerol 56:6 measurement	RAPSN FADS3	1.13e-03	43	34	2	EFO_0010433

Protein segments in the cluster

Peptide	Gene	Start	Entry
FMGKAQNQKYQGTVK	CEP295NL	426	Q96MC4
NFLNGNCMKVLKANG	FBXW10	641	Q5XX13
GQVVNQMNKKLQTGF	BMP2K	136	Q9NSY1
IMKGNINNYFKLGQE	BPTF	831	Q12830
KTGYNMVQENGQRKF	RBM46	31	Q8TBY0
MGQDQTKQQIEKGLQ	RAPSN	1	Q13702
VKMVNFLLKQGANVN	ANK2	741	Q01484
NFFNGNCMKVIKANG	FBXW10B	641	O95170
FVKKNGQCNIEFANM	KCNJ12	46	Q14500
FGKFIQLQLNRAQQM	MYO19	196	Q96H55
QMIGEFLGNRQKQFN	IQSEC2	801	Q5JU85
PNENKFRGFMQKFGN	FAM83B	991	Q5T0W9
TGEKLNQFNNQPMAK	CSNKA2IP	31	A0A1B0GTH6
YVFQGIDGKNIKMNN	TUBGCP3	256	Q96CW5
DIVQQFKMQLLKGGQ	ICOS	46	Q9Y6W8
IDQNDFNQMKGFVQA	ITGAD	161	Q13349
NSGNQKMEAVQKINY	CD109	406	Q6YHK3
GNEKEFMKGNQLISN	CLCN6	641	P51797
NNFANGDKQMKNSNF	DOCK10	1636	Q96BY6
GQNYMKERKGFNLQG	ELOVL3	51	Q9HB03
NKELMQQNGIGYVLN	DUSP16	176	Q9BY84
SGKVFQNKMANGNQP	HORMAD1	336	Q86X24
NHVAQKFVMGQLKGF	FADS3	196	Q9Y5Q0
KNFGIGEKMQEQQQA	SLC13A2	296	Q13183
DNNMNIKIADFGFGN	SIK2	151	Q9H0K1
FNQQKKKFGGQDIFM	SCN3A	1471	Q9NY46
FNQQKKKFGGQDIFM	SCN1A	1486	P35498
LNQMNNGNGANKKVE	APC	2401	P25054
EKMISQGNNNKNGKN	CNOT10	176	Q9H9A5
GNFQKKAANMLQQSG	RECQL	621	P46063
MQLIKGQTQNFKDAF	SLC7A11	211	Q9UPY5
FNQQKKKLGGQDIFM	SCN10A	1421	Q9Y5Y9
FNQQKKKFGGQDIFM	SCN2A	1476	Q99250
LQSQGQKFNIGIKNM	RHAG	101	Q02094
QKFNIGIKNMINADF	RHAG	106	Q02094
FNQQQKKLGGQDIFM	SCN11A	1311	Q9UI33