Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	recombination hotspot binding	PRDM9 PRDM7	4.11e-06	2	41	2	GO:0010844
GeneOntologyMolecularFunction	4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase activity	FUT4 FUT7	6.14e-05	6	41	2	GO:0017083
GeneOntologyMolecularFunction	alpha-(1->3)-fucosyltransferase activity	FUT4 FUT7	1.14e-04	8	41	2	GO:0046920
GeneOntologyMolecularFunction	voltage-gated chloride channel activity	CLCNKA CLCNKB	2.24e-04	11	41	2	GO:0005247
GeneOntologyMolecularFunction	histone H3K36 methyltransferase activity	PRDM9 PRDM7	3.16e-04	13	41	2	GO:0046975
GeneOntologyMolecularFunction	STAT family protein binding	FAM220BP FAM220A	3.16e-04	13	41	2	GO:0097677
GeneOntologyMolecularFunction	fucosyltransferase activity	FUT4 FUT7	3.69e-04	14	41	2	GO:0008417
GeneOntologyMolecularFunction	voltage-gated monoatomic anion channel activity	CLCNKA CLCNKB	5.49e-04	17	41	2	GO:0008308
GeneOntologyMolecularFunction	histone H3K4 methyltransferase activity	PRDM9 PRDM7	7.63e-04	20	41	2	GO:0042800
GeneOntologyBiologicalProcess	positive regulation of reciprocal meiotic recombination	PRDM9 PRDM7	2.54e-05	4	43	2	GO:0010845
GeneOntologyBiologicalProcess	regulation of reciprocal meiotic recombination	PRDM9 PRDM7	2.54e-05	4	43	2	GO:0010520
GeneOntologyBiologicalProcess	lymphocyte migration into lymph node	FUT4 FUT7	2.54e-05	4	43	2	GO:0097022
GeneOntologyBiologicalProcess	fucose catabolic process	FUT4 FUT7	1.51e-04	9	43	2	GO:0019317
GeneOntologyBiologicalProcess	L-fucose catabolic process	FUT4 FUT7	1.51e-04	9	43	2	GO:0042355
GeneOntologyBiologicalProcess	lymphocyte migration into lymphoid organs	FUT4 FUT7	1.89e-04	10	43	2	GO:0097021
GeneOntologyBiologicalProcess	transepithelial chloride transport	CLCNKA CLCNKB	1.89e-04	10	43	2	GO:0030321
GeneOntologyBiologicalProcess	L-fucose metabolic process	FUT4 FUT7	1.89e-04	10	43	2	GO:0042354
GeneOntologyBiologicalProcess	reciprocal meiotic recombination	PRDM9 PRDM7 SLX4	3.68e-04	67	43	3	GO:0007131
GeneOntologyBiologicalProcess	reciprocal homologous recombination	PRDM9 PRDM7 SLX4	3.68e-04	67	43	3	GO:0140527
GeneOntologyBiologicalProcess	positive regulation of binding	BLK FAM220BP MYOCD FAM220A	4.28e-04	170	43	4	GO:0051099
GeneOntologyBiologicalProcess	positive regulation of leukocyte tethering or rolling	FUT4 FUT7	4.38e-04	15	43	2	GO:1903238
GeneOntologyBiologicalProcess	homologous recombination	PRDM9 PRDM7 SLX4	4.93e-04	74	43	3	GO:0035825
GeneOntologyBiologicalProcess	fucose metabolic process	FUT4 FUT7	5.00e-04	16	43	2	GO:0006004
HumanPheno	Hypokalemic hypochloremic metabolic alkalosis	CLCNKA CLCNKB	3.14e-05	3	17	2	HP:0004909
HumanPheno	Hypochloremic metabolic alkalosis	CLCNKA CLCNKB	6.27e-05	4	17	2	HP:0005977
HumanPheno	Abnormal urine chloride concentration	CLCNKA CLCNKB	1.04e-04	5	17	2	HP:0012600
HumanPheno	Hyperchloriduria	CLCNKA CLCNKB	1.04e-04	5	17	2	HP:0002914
HumanPheno	Hyperprostaglandinuria	CLCNKA CLCNKB	1.56e-04	6	17	2	HP:0003527
HumanPheno	Abnormal circulating prostaglandin circulation	CLCNKA CLCNKB	1.56e-04	6	17	2	HP:0011023
HumanPheno	Hypochloremia	CLCNKA CLCNKB	2.18e-04	7	17	2	HP:0003113
HumanPheno	Impaired renal concentrating ability	CLCNKA CLCNKB	2.18e-04	7	17	2	HP:0004727
HumanPheno	Hyperactive renin-angiotensin system	CLCNKA CLCNKB	2.90e-04	8	17	2	HP:0000841
HumanPheno	Abnormal circulating unsaturated fatty acid concentration	CLCNKA CLCNKB	2.90e-04	8	17	2	HP:0011022
HumanPheno	Abnormal circulating eicosanoid concentration	CLCNKA CLCNKB	2.90e-04	8	17	2	HP:0030361
HumanPheno	Impaired renal function	CLCNKA CLCNKB	3.72e-04	9	17	2	HP:0000087
HumanPheno	Hypokalemic metabolic alkalosis	CLCNKA CLCNKB	3.72e-04	9	17	2	HP:0001960
HumanPheno	Increased urinary potassium	CLCNKA CLCNKB	3.72e-04	9	17	2	HP:0003081
HumanPheno	Acute kidney injury	CLCNKA CLCNKB CFB	3.76e-04	44	17	3	HP:0001919
HumanPheno	Hypernatriuria	CLCNKA CLCNKB	4.64e-04	10	17	2	HP:0012605
HumanPheno	Left ventricular noncompaction cardiomyopathy	MYOCD RYR2	4.64e-04	10	17	2	HP:0011664
HumanPheno	Hypokalemic alkalosis	CLCNKA CLCNKB	6.78e-04	12	17	2	HP:0001949
HumanPheno	Fetal polyuria	CLCNKA CLCNKB	6.78e-04	12	17	2	HP:0001563
MousePheno	abnormal urinary bladder morphology	FOXR1 AADAC MYOCD RAD54L2 TULP4 CLCNKB	2.54e-05	247	34	6	MP:0000538
Domain	Cl_channel-K	CLCNKA CLCNKB	4.70e-06	2	41	2	IPR002250
Domain	Glyco_transf_10	FUT4 FUT7	1.31e-04	8	41	2	PF00852
Domain	Glyco_tran_10_N	FUT4 FUT7	1.31e-04	8	41	2	PF17039
Domain	SSXRD	PRDM9 PRDM7	1.31e-04	8	41	2	PF09514
Domain	SSXRD_motif	PRDM9 PRDM7	1.31e-04	8	41	2	IPR019041
Domain	Glyco_trans_10	FUT4 FUT7	1.31e-04	8	41	2	IPR001503
Domain	Glyco_tran_10_N	FUT4 FUT7	1.31e-04	8	41	2	IPR031481
Domain	Cl-channel_core	CLCNKA CLCNKB	1.68e-04	9	41	2	IPR014743
Domain	-	CLCNKA CLCNKB	1.68e-04	9	41	2	1.10.3080.10
Domain	Voltage_CLC	CLCNKA CLCNKB	1.68e-04	9	41	2	PF00654
Domain	Cl-channel_volt-gated	CLCNKA CLCNKB	1.68e-04	9	41	2	IPR001807
Domain	KRAB_RELATED	PRDM9 PRDM7	2.55e-04	11	41	2	PS50806
Domain	Krueppel-associated_box-rel	PRDM9 PRDM7	3.61e-04	13	41	2	IPR003655
Domain	CBS	CLCNKA CLCNKB	5.53e-04	16	41	2	SM00116
Domain	CBS_dom	CLCNKA CLCNKB	8.71e-04	20	41	2	IPR000644
Domain	CBS	CLCNKA CLCNKB	8.71e-04	20	41	2	PF00571
Domain	CBS	CLCNKA CLCNKB	8.71e-04	20	41	2	PS51371
Domain	SET	PRDM9 PRDM7	4.58e-03	46	41	2	SM00317
Domain	FORK_HEAD_3	FOXR1 FOXR2	5.18e-03	49	41	2	PS50039
Domain	FH	FOXR1 FOXR2	5.18e-03	49	41	2	SM00339
Domain	FORK_HEAD_1	FOXR1 FOXR2	5.18e-03	49	41	2	PS00657
Domain	FORK_HEAD_2	FOXR1 FOXR2	5.18e-03	49	41	2	PS00658
Domain	Forkhead	FOXR1 FOXR2	5.18e-03	49	41	2	PF00250
Domain	Fork_head_dom	FOXR1 FOXR2	5.18e-03	49	41	2	IPR001766
Domain	SET_dom	PRDM9 PRDM7	5.39e-03	50	41	2	IPR001214
Domain	SET	PRDM9 PRDM7	5.39e-03	50	41	2	PS50280
Domain	-	ETV2 FOXR1 FOXR2	1.21e-02	218	41	3	1.10.10.10
Pathway	KEGG_MEDICUS_REFERENCE_SIALYL_LEWIS_X_ANTIGEN_BIOSYNTHESIS	FUT4 FUT7	4.88e-05	6	26	2	M47967
Pathway	BIOCARTA_AMAN_PATHWAY	FUT4 FUT7	1.17e-04	9	26	2	MM1535
Pathway	BIOCARTA_AMAN_PATHWAY	FUT4 FUT7	3.38e-04	15	26	2	M22009
Pathway	REACTOME_BLOOD_GROUP_SYSTEMS_BIOSYNTHESIS	FUT4 FUT7	4.37e-04	17	26	2	MM15629
Pathway	REACTOME_BLOOD_GROUP_SYSTEMS_BIOSYNTHESIS	FUT4 FUT7	6.72e-04	21	26	2	M27917
Pathway	REACTOME_STIMULI_SENSING_CHANNELS	CLCNKA CLCNKB RYR2	7.77e-04	99	26	3	MM14910
Pathway	REACTOME_STIMULI_SENSING_CHANNELS	CLCNKA CLCNKB RYR2	9.47e-04	106	26	3	M27200
Pathway	KEGG_GLYCOSPHINGOLIPID_BIOSYNTHESIS_LACTO_AND_NEOLACTO_SERIES	FUT4 FUT7	1.03e-03	26	26	2	M17377
Pubmed	Lack of functional selectin ligand interactions compromises long term tumor protection by CD8+ T cells.	FUT4 FUT7	1.64e-06	2	45	2	22359671
Pubmed	Cloning, tissue distribution, and intrarenal localization of ClC chloride channels in human kidney.	CLCNKA CLCNKB	1.64e-06	2	45	2	8544406
Pubmed	α(1,3)-Fucosyltransferases FUT4 and FUT7 control murine susceptibility to thrombosis.	FUT4 FUT7	1.64e-06	2	45	2	23562273
Pubmed	The ClC-K2 Chloride Channel Is Critical for Salt Handling in the Distal Nephron.	CLCNKA CLCNKB	1.64e-06	2	45	2	27335120
Pubmed	Lack of functional selectin-ligand interactions enhances innate immune resistance to systemic Listeria monocytogenes infection.	FUT4 FUT7	1.64e-06	2	45	2	29345354
Pubmed	Assignment of the genes encoding the human chloride channels, CLCNKA and CLCNKB, to 1p36 and of CLCN3 to 4q32-q33 by in situ hybridization.	CLCNKA CLCNKB	1.64e-06	2	45	2	8812470
Pubmed	The alpha(1,3)fucosyltransferase Fuc-TVII controls leukocyte trafficking through an essential role in L-, E-, and P-selectin ligand biosynthesis.	FUT4 FUT7	1.64e-06	2	45	2	8752218
Pubmed	A regulatory calcium-binding site at the subunit interface of CLC-K kidney chloride channels.	CLCNKA CLCNKB	1.64e-06	2	45	2	20805576
Pubmed	Associations between CLCNKA_B tag SNPs with essential hypertension and interactions between genetic and environmental factors in an island population in China.	CLCNKA CLCNKB	1.64e-06	2	45	2	25919862
Pubmed	Targeting kidney CLC-K channels: pharmacological profile in a human cell line versus Xenopus oocytes.	CLCNKA CLCNKB	1.64e-06	2	45	2	24863058
Pubmed	Overt nephrogenic diabetes insipidus in mice lacking the CLC-K1 chloride channel.	CLCNKA CLCNKB	1.64e-06	2	45	2	9916798
Pubmed	Kidney kinetics and chloride ion pumps.	CLCNKA CLCNKB	1.64e-06	2	45	2	9916791
Pubmed	Synthesis of {alpha}(1,3) fucosyltransferases IV- and VII-dependent eosinophil selectin ligand and recruitment to the skin.	FUT4 FUT7	1.64e-06	2	45	2	16127157
Pubmed	Fucosyltransferase 4 and 7 mediates adhesion of non-small cell lung cancer cells to brain-derived endothelial cells and results in modification of the blood-brain-barrier: in vitro investigation of CD15 and CD15s in lung-to-brain metastasis.	FUT4 FUT7	1.64e-06	2	45	2	31104223
Pubmed	Regulation of PSGL-1 interactions with L-selectin, P-selectin, and E-selectin: role of human fucosyltransferase-IV and -VII.	FUT4 FUT7	1.64e-06	2	45	2	15579466
Pubmed	Fuc-TVII is required for T helper 1 and T cytotoxic 1 lymphocyte selectin ligand expression and recruitment in inflammation, and together with Fuc-TIV regulates naive T cell trafficking to lymph nodes.	FUT4 FUT7	1.64e-06	2	45	2	11535629
Pubmed	The alpha(1,3)fucosyltransferases FucT-IV and FucT-VII exert collaborative control over selectin-dependent leukocyte recruitment and lymphocyte homing.	FUT4 FUT7	1.64e-06	2	45	2	11485743
Pubmed	Abrogation of functional selectin-ligand expression reduces migration of pathogenic CD8+ T cells into heart.	FUT4 FUT7	1.64e-06	2	45	2	16709814
Pubmed	Fucosyltransferase Induction during Influenza Virus Infection Is Required for the Generation of Functional Memory CD4+ T Cells.	FUT4 FUT7	1.64e-06	2	45	2	29491007
Pubmed	Memory T cells are enriched in lymph nodes of selectin-ligand-deficient mice.	FUT4 FUT7	1.64e-06	2	45	2	20937846
Pubmed	Fucosyltransferase IV and VII-directed selectin ligand function determines long-term survival in experimental tuberculosis.	FUT4 FUT7	1.64e-06	2	45	2	19608009
Pubmed	Salt wasting and deafness resulting from mutations in two chloride channels.	CLCNKA CLCNKB	1.64e-06	2	45	2	15044642
Pubmed	Expanding Genotype-Phenotype Correlation of CLCNKA and CLCNKB Variants Linked to Hearing Loss.	CLCNKA CLCNKB	1.64e-06	2	45	2	38069401
Pubmed	Pathophysiological contributions of fucosyltransferases in renal ischemia reperfusion injury.	FUT4 FUT7	1.64e-06	2	45	2	12193737
Pubmed	Two highly homologous members of the ClC chloride channel family in both rat and human kidney.	CLCNKA CLCNKB	1.64e-06	2	45	2	8041726
Pubmed	Selectin ligand-independent priming and maintenance of T cell immunity during airborne tuberculosis.	FUT4 FUT7	1.64e-06	2	45	2	16394002
Pubmed	A cytoplasmic domain mutation in ClC-Kb affects long-distance communication across the membrane.	CLCNKA CLCNKB	1.64e-06	2	45	2	18648499
Pubmed	Cl(-) channels in basolateral TAL membranes XV. Molecular heterogeneity between cortical and medullary channels.	CLCNKA CLCNKB	1.64e-06	2	45	2	11014860
Pubmed	Naïve T cells re-distribute to the lungs of selectin ligand deficient mice.	FUT4 FUT7	4.91e-06	3	45	2	20532047
Pubmed	Silencing α1,3-fucosyltransferases in human leukocytes reveals a role for FUT9 enzyme during E-selectin-mediated cell adhesion.	FUT4 FUT7	4.91e-06	3	45	2	23192350
Pubmed	Murine neutrophils require alpha1,3-fucosylation but not PSGL-1 for productive infection with Anaplasma phagocytophilum.	FUT4 FUT7	4.91e-06	3	45	2	12869507
Pubmed	Suppression of tumor formation in lymph nodes by L-selectin-mediated natural killer cell recruitment.	FUT4 FUT7	4.91e-06	3	45	2	16352740
Pubmed	Human CLC-K Channels Require Palmitoylation of Their Accessory Subunit Barttin to Be Functional.	CLCNKA CLCNKB	4.91e-06	3	45	2	26013830
Pubmed	Barttin increases surface expression and changes current properties of ClC-K channels.	CLCNKA CLCNKB	4.91e-06	3	45	2	12111250
Pubmed	T-cell P/E-selectin ligand alpha(1,3)fucosylation is not required for graft-vs-host disease induction.	FUT4 FUT7	4.91e-06	3	45	2	16338500
Pubmed	Binding of L-selectin to its vascular and extravascular ligands is differentially regulated by pH.	FUT4 FUT7	4.91e-06	3	45	2	21982762
Pubmed	Alpha(1,3)fucosyltransferases FucT-IV and FucT-VII control susceptibility to atherosclerosis in apolipoprotein E-/- mice.	FUT4 FUT7	4.91e-06	3	45	2	15308551
Pubmed	Barttin is a Cl- channel beta-subunit crucial for renal Cl- reabsorption and inner ear K+ secretion.	CLCNKA CLCNKB	4.91e-06	3	45	2	11734858
Pubmed	Metastatic growth progression caused by PSGL-1-mediated recruitment of monocytes to metastatic sites.	FUT4 FUT7	4.91e-06	3	45	2	24322980
Pubmed	Common genetic variants and haplotypes in renal CLCNKA gene are associated to salt-sensitive hypertension.	CLCNKA CLCNKB	4.91e-06	3	45	2	17510212
Pubmed	CD15 expression in mature granulocytes is determined by alpha 1,3-fucosyltransferase IX, but in promyelocytes and monocytes by alpha 1,3-fucosyltransferase IV.	FUT4 FUT7	4.91e-06	3	45	2	11278338
Pubmed	Barttin modulates trafficking and function of ClC-K channels.	CLCNKA CLCNKB	4.91e-06	3	45	2	16849430
Pubmed	Endothelial E-selectin inhibition improves acute myeloid leukaemia therapy by disrupting vascular niche-mediated chemoresistance.	FUT4 FUT7	4.91e-06	3	45	2	32341362
Pubmed	A role for leukocyte-endothelial adhesion mechanisms in epilepsy.	FUT4 FUT7	4.91e-06	3	45	2	19029985
Pubmed	Efficient recruitment of lymphocytes in inflamed brain venules requires expression of cutaneous lymphocyte antigen and fucosyltransferase-VII.	FUT4 FUT7	4.91e-06	3	45	2	15843584
Pubmed	α(1,3) Fucosyltransferases IV and VII are essential for the initial recruitment of basophils in chronic allergic inflammation.	FUT4 FUT7	4.91e-06	3	45	2	23657464
Pubmed	SIPAR negatively regulates STAT3 signaling and inhibits progression of melanoma.	FAM220BP FAM220A	4.91e-06	3	45	2	23917203
Pubmed	Skin infection generates non-migratory memory CD8+ T(RM) cells providing global skin immunity.	FUT4 FUT7	4.91e-06	3	45	2	22388819
Pubmed	Mechanisms of Disease: the kidney-specific chloride channels ClCKA and ClCKB, the Barttin subunit, and their clinical relevance.	CLCNKA CLCNKB	4.91e-06	3	45	2	18094726
Pubmed	Transcriptional regulation of the CLC-K1 promoter by myc-associated zinc finger protein and kidney-enriched Krüppel-like factor, a novel zinc finger repressor.	CLCNKA CLCNKB	4.91e-06	3	45	2	10982849
Pubmed	Unique alternative translation from two open reading frames on Acpin1 mRNA yields an acrosomal protein and a salivary-gland-specific protein.	FAM220BP FAM220A	4.91e-06	3	45	2	19659802
Pubmed	A novel monoclonal antibody against 6-sulfo sialyl Lewis x glycans attenuates murine allergic rhinitis by suppressing Th2 immune responses.	FUT4 FUT7	9.81e-06	4	45	2	37735247
Pubmed	Heparin-induced leukocytosis requires 6-O-sulfation and is caused by blockade of selectin- and CXCL12 protein-mediated leukocyte trafficking in mice.	FUT4 FUT7	9.81e-06	4	45	2	22194593
Pubmed	Haplotype diversity in four genes (CLCNKA, CLCNKB, BSND, NEDD4L) involved in renal salt reabsorption.	CLCNKA CLCNKB	9.81e-06	4	45	2	17652939
Pubmed	Monocyte Induction of E-Selectin-Mediated Endothelial Activation Releases VE-Cadherin Junctions to Promote Tumor Cell Extravasation in the Metastasis Cascade.	FUT4 FUT7	9.81e-06	4	45	2	27488527
Pubmed	Specialized contributions by alpha(1,3)-fucosyltransferase-IV and FucT-VII during leukocyte rolling in dermal microvessels.	FUT4 FUT7	9.81e-06	4	45	2	10894166
Pubmed	The Lewis X-related α1,3-fucosyltransferase, Fut10, is required for the maintenance of stem cell populations.	FUT4 FUT7	9.81e-06	4	45	2	23986452
Pubmed	Notch-dependent control of myelopoiesis is regulated by fucosylation.	FUT4 FUT7	9.81e-06	4	45	2	18359890
Pubmed	Expression of functional P-selectin glycoprotein ligand 1 on hematopoietic progenitors is developmentally regulated.	FUT4 FUT7	9.81e-06	4	45	2	22461691
Pubmed	Arteriogenesis proceeds via ICAM-1/Mac-1- mediated mechanisms.	FUT4 FUT7	9.81e-06	4	45	2	15059933
Pubmed	Skin-homing receptors on effector leukocytes are differentially sensitive to glyco-metabolic antagonism in allergic contact dermatitis.	FUT4 FUT7	9.81e-06	4	45	2	18056398
Pubmed	Genome-wide survey and developmental expression mapping of zebrafish SET domain-containing genes.	PRDM9 PRDM7	9.81e-06	4	45	2	18231586
Pubmed	Cellular players and role of selectin ligands in leukocyte recruitment in a T-cell-initiated delayed-type hypersensitivity reaction.	FUT4 FUT7	9.81e-06	4	45	2	18755847
Pubmed	Sorcin is an early marker of neurodegeneration, Ca2+ dysregulation and endoplasmic reticulum stress associated to neurodegenerative diseases.	SIGMAR1 RYR2	1.63e-05	5	45	2	33060591
Pubmed	Nuclear termination of STAT3 signaling through SIPAR (STAT3-Interacting Protein As a Repressor)-dependent recruitment of T cell tyrosine phosphatase TC-PTP.	FAM220BP FAM220A	1.63e-05	5	45	2	26026268
Pubmed	The sphingosine 1-phosphate receptor 1 causes tissue retention by inhibiting the entry of peripheral tissue T lymphocytes into afferent lymphatics.	FUT4 FUT7	1.63e-05	5	45	2	18037890
Pubmed	N-acetylglucosamine-6-O-sulfotransferases 1 and 2 cooperatively control lymphocyte homing through L-selectin ligand biosynthesis in high endothelial venules.	FUT4 FUT7	1.63e-05	5	45	2	16227985
Pubmed	Dual inhibition of endothelial miR-92a-3p and miR-489-3p reduces renal injury-associated atherosclerosis.	FAM220BP FAM220A	1.63e-05	5	45	2	30731284
Pubmed	Novel anti-carbohydrate antibodies reveal the cooperative function of sulfated N- and O-glycans in lymphocyte homing.	FUT4 FUT7	2.45e-05	6	45	2	20929857
Pubmed	Functional contributions of N- and O-glycans to L-selectin ligands in murine and human lymphoid organs.	FUT4 FUT7	2.45e-05	6	45	2	21224079
Pubmed	Embryonic trafficking of gammadelta T cells to skin is dependent on E/P selectin ligands and CCR4.	FUT4 FUT7	2.45e-05	6	45	2	20368416
Pubmed	L-selectin mechanochemistry restricts neutrophil priming in vivo.	FUT4 FUT7	2.45e-05	6	45	2	28497779
Pubmed	Physiological contribution of CD44 as a ligand for E-Selectin during inflammatory T-cell recruitment.	FUT4 FUT7	2.45e-05	6	45	2	21457936
Pubmed	DC-SIGN(+) Macrophages Control the Induction of Transplantation Tolerance.	FUT4 FUT7	3.42e-05	7	45	2	26070485
Pubmed	Sialyltransferase ST3Gal-III regulates Siglec-F ligand formation and eosinophilic lung inflammation in mice.	FUT4 FUT7	3.42e-05	7	45	2	23677475
Pubmed	Impairment in renal medulla development underlies salt wasting in Clc-k2 channel deficiency.	CLCNKA CLCNKB	3.42e-05	7	45	2	34499620
Pubmed	Intrarenal and cellular localization of CLC-K2 protein in the mouse kidney.	CLCNKA CLCNKB	3.42e-05	7	45	2	11423561
Pubmed	The yin-yang of PR-domain family genes in tumorigenesis.	PRDM9 PRDM7	3.42e-05	7	45	2	10668202
Pubmed	SET domains and histone methylation.	PRDM9 PRDM7	4.56e-05	8	45	2	14675547
Pubmed	Phagocytosis of apoptotic neutrophils regulates granulopoiesis via IL-23 and IL-17.	FUT4 FUT7	5.86e-05	9	45	2	15780986
Pubmed	Changing expression of chloride channels during preimplantation mouse development.	CLCNKA CLCNKB	5.86e-05	9	45	2	23115349
Pubmed	Regulatory T cells sequentially migrate from inflamed tissues to draining lymph nodes to suppress the alloimmune response.	FUT4 FUT7	8.94e-05	11	45	2	19303390
Pubmed	Composition of Drosophila melanogaster proteome involved in fucosylated glycan metabolism.	FUT4 FUT7	1.70e-04	15	45	2	11698403
Pubmed	Heart-specific ablation of Prkar1a causes failure of heart development and myxomagenesis.	MYOCD RYR2	2.76e-04	19	45	2	18316483
Pubmed	Local protease signaling contributes to neural tube closure in the mouse embryo.	PRSS36 CFB	3.06e-04	20	45	2	20152175
Pubmed	Congenital heart defect causing mutation in Nkx2.5 displays in vivo functional deficit.	ETV2 RYR2	3.38e-04	21	45	2	28302382
Pubmed	The Isl1/Ldb1 Complex Orchestrates Genome-wide Chromatin Organization to Instruct Differentiation of Multipotent Cardiac Progenitors.	MYOCD RYR2	4.07e-04	23	45	2	26321200
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	TMEM131L ABCA2 PACSIN1 ARHGAP31 SMG6	5.91e-04	529	45	5	14621295
Pubmed	Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development.	CLCNKA CLCNKB RYR2	7.84e-04	139	45	3	16985003
Pubmed	A phenotype survey of 36 mutant mouse strains with gene-targeted defects in glycosyltransferases or glycan-binding proteins.	FUT4 FUT7	8.43e-04	33	45	2	23118208
Pubmed	Pioneering function of Isl1 in the epigenetic control of cardiomyocyte cell fate.	MYOCD RYR2	8.94e-04	34	45	2	31024170
GeneFamily	Chloride voltage-gated channels	CLCNKA CLCNKB	7.55e-05	10	24	2	302
GeneFamily	Fucosyltransferases\|Blood group antigens	FUT4 FUT7	1.31e-04	13	24	2	434
GeneFamily	Zinc fingers C2H2-type\|PR/SET domain family	PRDM9 PRDM7	2.27e-04	17	24	2	1197
GeneFamily	Forkhead boxes	FOXR1 FOXR2	1.48e-03	43	24	2	508
GeneFamily	SH2 domain containing	BLK BCAR3	7.87e-03	101	24	2	741
ToppCell	356C-Myeloid-Macrophage-SPP1+_Macrophage_4\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	PRDM7 SLX4 PRSS36 CFB	4.34e-06	108	45	4	ee924deacd14ea404fda80ed633960143fd474c0
ToppCell	Severe-B_naive-5\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	CSRNP1 FHL1 DNAH10 PACSIN1	1.72e-05	153	45	4	44572f87d403e314050ab935d2cd676c33d9c287
ToppCell	facs-Lung-nan-3m-Endothelial-Capillary_Type_1_Cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AADAC MYOCD DNAH10 RYR2	2.05e-05	160	45	4	f2cdee5a9e3b0eb125d6be7b5d239eb04333ae41
ToppCell	356C-Myeloid-Macrophage-SPP1+_Macrophage_4\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	PRDM7 SLX4 PRSS36 CFB	2.37e-05	166	45	4	8d5d09f25e8903d481c2097fed435e69d42ccdb5
ToppCell	CV-Mild-6\|CV / Virus stimulation, Condition and Cluster	FUT7 DNAH10 UBL3 PRSS36	2.42e-05	167	45	4	cf2ed0b6d17a16f9a2318879ce8856d5983ad3cf
ToppCell	droplet-Lung-nan-21m-Myeloid-Plasmacytoid_Dendritic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FOXR1 SIGMAR1 PACSIN1 CFAP65	2.78e-05	173	45	4	8fb32a9f2dbec16de840d55b4db7e7718f5a2a7a
ToppCell	droplet-Lung-nan-21m-Myeloid-plasmacytoid_dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FOXR1 SIGMAR1 PACSIN1 CFAP65	2.78e-05	173	45	4	f663571aaae2365660a8b526c355f4bd1a124a74
ToppCell	CV-Mild-6\|Mild / Virus stimulation, Condition and Cluster	DNAH10 UBL3 ERV3-1 PRSS36	2.91e-05	175	45	4	c4d530dbb37942427c9cd0a1533faeb6a3a45381
ToppCell	COVID-19-Heart-CM_3\|COVID-19 / Disease (COVID-19 only), tissue and cell type	MYOCD ITGA7 FHL1 RYR2	2.97e-05	176	45	4	9df7a124ebafb0087da0cda133a394275d7bed81
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TMEM131L MYOCD ITGA7 RYR2	3.77e-05	187	45	4	958402fcc78f4c7a7d13d659d776f3817137975f
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TMEM131L MYOCD ITGA7 RYR2	3.77e-05	187	45	4	48bfdb3504c3fefe5db3abac4b790c369680ab4e
ToppCell	LA-03._Atrial_Cardiomyocyte\|World / Chamber and Cluster_Paper	MYOCD ITGA7 FHL1 RYR2	3.85e-05	188	45	4	6d249fe92d51a19da19ec14bb2262d394255d577
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TMEM131L MYOCD ITGA7 RYR2	3.85e-05	188	45	4	b2d68a32314e9b099ed74d974079ad96359d1ae3
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TMEM131L MYOCD ITGA7 RYR2	3.93e-05	189	45	4	7fbe855bfdb47d35e040b04a80fe4b729a3764e8
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TMEM131L MYOCD ITGA7 RYR2	3.93e-05	189	45	4	fac5c291a9a87418bb0878c3d624829bdbf1f428
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TMEM131L MYOCD ITGA7 RYR2	3.93e-05	189	45	4	2cfb4d12f75678d1619f4743838a0e954bd57761
ToppCell	5'-Adult-Appendix-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MYOCD ITGA7 FHL1 RYR2	3.93e-05	189	45	4	b6bb4327b4560d07d2b728abcc5f144f428948a5
ToppCell	5'-Adult-Appendix-Mesenchymal-Pericytes\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MYOCD ITGA7 FHL1 RYR2	3.93e-05	189	45	4	0daa8efac08dca9525d2b8d421952068cab4eb50
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TMEM131L MYOCD ITGA7 RYR2	3.93e-05	189	45	4	06b35abecd29f902cf251fcc1f6ad33db7ab08a2
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TMEM131L MYOCD ITGA7 RYR2	3.93e-05	189	45	4	127ad2ba3e794df8cce2eee3e4171bccb5aad51b
ToppCell	COVID-19-Heart\|COVID-19 / Disease (COVID-19 only), tissue and cell type	MYOCD ITGA7 FHL1 RYR2	4.01e-05	190	45	4	918ad5037881212008f9f69d5df5da91fd01422c
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TMEM131L MYOCD FHL1 RYR2	4.01e-05	190	45	4	f5fb989afabb49d64d91324570cd8c80a4b9e67d
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TMEM131L MYOCD FHL1 RYR2	4.01e-05	190	45	4	562ee3b025c29edf07b8b344323edb49d82f1c7e
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TMEM131L MYOCD ITGA7 RYR2	4.18e-05	192	45	4	b54b0d5b88139905521c8d5d58332e89c08d589c
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TMEM131L MYOCD ITGA7 RYR2	4.18e-05	192	45	4	bfab13793e54de2550ee171397f7ece0625cdb4a
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TMEM131L MYOCD ITGA7 RYR2	4.35e-05	194	45	4	5c3b2b05d1e4f146551fe4c920263d8e6ca34de3
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TMEM131L MYOCD ITGA7 RYR2	4.35e-05	194	45	4	ab9cad697f9209d2889bc02b43b502dfeb2ebfef
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MYOCD ITGA7 FHL1 RYR2	4.53e-05	196	45	4	1522958a92e0126326a9f0d9fb1c5b5c50b001ea
ToppCell	5'-Adult-SmallIntestine-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MYOCD ITGA7 FHL1 RYR2	4.53e-05	196	45	4	ce6f7ddb8104471dc90347f427486379914d63b4
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MYOCD ITGA7 FHL1 RYR2	4.53e-05	196	45	4	1c8294014713684b50885e638668f2ce75f357f0
ToppCell	5'-Adult-SmallIntestine-Mesenchymal-Pericytes\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MYOCD ITGA7 FHL1 RYR2	4.53e-05	196	45	4	6d7179decea512dd49bb2d5f6a4f5989349d52a9
ToppCell	Bronchial-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MYOCD ITGA7 FHL1 RYR2	4.53e-05	196	45	4	9830fb3da7a60f65ad463e9054bb77c06b025e4d
ToppCell	Bronchial-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_pulmonary\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MYOCD ITGA7 FHL1 RYR2	4.62e-05	197	45	4	bf0520a94ebb1d2f94de9f526d17e0b0e8fe7052
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MYOCD ITGA7 FHL1 RYR2	4.62e-05	197	45	4	d16bb765afdc02406ffd7ce6a75bae72b66db66c
ToppCell	Tracheal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_pulmonary\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MYOCD ITGA7 FHL1 RYR2	4.62e-05	197	45	4	ac4f53acb2f8a428b0f2fab3c30a34e095a1bed7
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-Pericytes\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MYOCD ITGA7 FHL1 RYR2	4.62e-05	197	45	4	68c23c23b6924892f4c238cf2f5abc7927e04fbc
ToppCell	Bronchial-10x5prime-Stromal-Myofibroblastic-Muscle_perivascular_immune_recruiting\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	MYOCD PROB1 ITGA7 RYR2	4.71e-05	198	45	4	dc6d9032c5029527e184ac13b887c0c1f22ef1c0
ToppCell	Tracheal-NucSeq-Stromal-Myofibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MYOCD ITGA7 FHL1 RYR2	4.71e-05	198	45	4	c12e7511628db819a52959bb68580e27c00c2e41
ToppCell	Tracheal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MYOCD ITGA7 FHL1 RYR2	4.71e-05	198	45	4	22e766df1276c5b14aa0d83f434f47140ebb98ea
ToppCell	Bronchus_Control_(B.)-Stromal-TX-Smooth_muscle-2\|Bronchus_Control_(B.) / Sample group, Lineage and Cell type	MYOCD ITGA7 FHL1 RYR2	4.80e-05	199	45	4	2c5ad62919c64ea0242e0984bb9932d2d975f4e3
ToppCell	Tracheal-10x5prime-Stromal-Myofibroblastic\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	MYOCD ITGA7 FHL1 RYR2	4.80e-05	199	45	4	0a145172787f40d0fdaf21188d539ffaf7ece3e4
ToppCell	MS-IIF-Lymphocyte-T/NK-NK_CD56bright\|IIF / Disease, condition lineage and cell class	PROB1 FUT7 PACSIN1 BAZ2B	4.80e-05	199	45	4	9eb2b7d4900b118338590db778a47504559e228d
ToppCell	Parenchymal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_pulmonary\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MYOCD ITGA7 FHL1 RYR2	4.80e-05	199	45	4	b1753474152b82a0b811b9878c890a359e14919a
ToppCell	Bronchial-NucSeq-Stromal-Myofibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MYOCD ITGA7 FHL1 RYR2	4.89e-05	200	45	4	a66449b22b39dd6987fc2c3ed160d24564234ced
ToppCell	Hippocampus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Rbp4-Inhibitory_Neuron.Gad1Gad2_Sst.Rbp4_(Interneuron,_OLM2_(CA1_enriched?))\|Hippocampus / BrainAtlas - Mouse McCarroll V32	FUT7 CLCNKB ERV3-1	6.49e-05	77	45	3	9a29879348b32b6c2302820f75fd55efba39aae8
ToppCell	Hippocampus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Rbp4\|Hippocampus / BrainAtlas - Mouse McCarroll V32	FUT7 CLCNKB ERV3-1	6.49e-05	77	45	3	3763b55e5ce44b844da661e9024c9f2c847ea26f
ToppCell	Hippocampus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Rbp4-Inhibitory_Neuron.Gad1Gad2_Sst.Rbp4_(Interneuron,_OLM2_(CA1_enriched?))-\|Hippocampus / BrainAtlas - Mouse McCarroll V32	FUT7 CLCNKB ERV3-1	6.49e-05	77	45	3	c5262a0d2040b2c580601e5a8d1ec626a0c7b560
ToppCell	Globus_pallidus-Macroglia-POLYDENDROCYTE-P1-Tnr\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	DNAH10 UBL3 DCT	8.72e-05	85	45	3	159b3ac93490c3e4918ea61f8ede7add9e63ca40
ToppCell	COVID-19_Severe-Neu_3\|COVID-19_Severe / 5 Neutrophil clusters in COVID-19 patients	BCAR3 PRDM7 CFB	2.60e-04	123	45	3	4c20c025b6f19f075a13282288fc537e6e186217
ToppCell	COVID-19_Severe-Neu_3\|World / 5 Neutrophil clusters in COVID-19 patients	BCAR3 PRDM7 CFB	2.66e-04	124	45	3	54b42ffb161eece4ae308782e43a0e0dc360281e
ToppCell	Globus_pallidus-Macroglia-POLYDENDROCYTE-P1\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	DNAH10 UBL3 DCT	3.57e-04	137	45	3	80f1a6cfb48ccfba1c3545fdcd5fcb3157272aca
ToppCell	Entopeduncular-Macroglia-POLYDENDROCYTE\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	DNAH10 UBL3 DCT	4.30e-04	146	45	3	a317f14a1aab11ffcce65baeb1c475c04324315f
ToppCell	droplet-Heart-4Chambers-18m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FOXR1 AADAC CLCNKB	4.56e-04	149	45	3	38890ddde0979977c8350f01497f1245ab51641a
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MYOCD ITGA7 RYR2	4.83e-04	152	45	3	0cb5f4dfae04e3f4eba502bbf229007d5fa3884d
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MYOCD ITGA7 RYR2	4.83e-04	152	45	3	ee329249a034a969a16b26a224aa04249d67382d
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MYOCD ITGA7 RYR2	4.83e-04	152	45	3	bd1f36b436d8ab7dd8420f595b97d851eab31a38
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MYOCD ITGA7 RYR2	4.83e-04	152	45	3	ba89ffb5a8bb33c188f854f54b39123b6d73496a
ToppCell	390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0.5\|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)	DNAH10 ARHGAP31 CFB	4.93e-04	153	45	3	e7d20c88466ff81db613869cf7a6a4bb95fd6c2f
ToppCell	390C-Lymphocytic-NK_cells-NK_cell_D2\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	FUT7 PACSIN1 PSMG3-AS1	5.12e-04	155	45	3	216a240bfb82cdefc59e2f342689dbaaacb7c184
ToppCell	Severe-B_naive-5\|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)	CSRNP1 FHL1 DNAH10	5.31e-04	157	45	3	a57ee4a6febdff3ee3d1645836695e6e7c055cf8
ToppCell	Adult-Mesenchymal-vascular_smooth_muscle_cell-D231\|Adult / Lineage, Cell type, age group and donor	MYOCD ITGA7 RYR2	5.41e-04	158	45	3	8d64c0c9de910a3f4658778642d183c8b9b6f6a2
ToppCell	Children_(3_yrs)-Mesenchymal-vascular_smooth_muscle_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	MYOCD PROB1 ITGA7	5.41e-04	158	45	3	84c0a215dabf697ada036c2b9592d0c61b5077de
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYOCD DNAH10 RYR2	5.61e-04	160	45	3	c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell	Adult-Mesenchymal-vascular_smooth_muscle_cell-D122\|Adult / Lineage, Cell type, age group and donor	MYOCD ITGA7 RYR2	5.61e-04	160	45	3	fd14dfeb7021a4b7299371854dc8fc1fd66c8dae
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYOCD DNAH10 RYR2	5.61e-04	160	45	3	25c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell	facs-Lung-Endomucin_-18m-Lymphocytic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BLK PRDM9 BCAR3	5.82e-04	162	45	3	e81dec1db8e5a808d96e58410c91961e5d065c94
ToppCell	facs-Lung-Endomucin_-18m-Lymphocytic-B_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BLK PRDM9 BCAR3	5.82e-04	162	45	3	d19b469f64c9064cfb82dadb6c8135e28949a02a
ToppCell	facs-Lung-Endomucin_-18m-Lymphocytic-B_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BLK PRDM9 BCAR3	5.82e-04	162	45	3	10c2aa047f33f48e4abe676236bbdb593079dd1d
ToppCell	ILEUM-non-inflamed-(3)_pDC\|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	FUT7 DNAH10OS PACSIN1	5.92e-04	163	45	3	bc5411702badab39143905aa51676b4bbfad2041
ToppCell	droplet-Lung-3m-Hematologic-myeloid-plasmacytoid_dendritic_cell-plasmacytoid_dendritic\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FOXR1 FUT7 PACSIN1	6.03e-04	164	45	3	cfe07a1ebed8aecb08d0476db71fe314998d54aa
ToppCell	droplet-Lung-3m-Hematologic-myeloid-plasmacytoid_dendritic_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FOXR1 FUT7 PACSIN1	6.03e-04	164	45	3	6d331e74efecb4733d87653f86cd67247be05025
ToppCell	367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_3\|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)	FUT7 PTCD1 ARHGAP31	6.03e-04	164	45	3	d2218d50e0e2d19f919dcb460b3840687c082810
ToppCell	NS-control-d_0-4-Myeloid-pDC\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	FUT7 PACSIN1 ARHGAP31	6.14e-04	165	45	3	8b2d43d7c4ee07bd999bd51bc15117ce1fbb2d86
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MYOCD ITGA7 RYR2	6.36e-04	167	45	3	7cb1b11e8e24a10115e46ffbb74889e672a7a026
ToppCell	ILEUM-non-inflamed-(3)_MNP-(3)_pDC\|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	FHL1 DNAH10OS PACSIN1	6.36e-04	167	45	3	8ddf9da71a7c4ed53588435db826563a24cee616
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MYOCD ITGA7 RYR2	6.36e-04	167	45	3	bb53a478b5d821d6d82c15bc4ed075b67682457c
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MYOCD ITGA7 RYR2	6.36e-04	167	45	3	e228b8373ffd4436e6b944e26d0fadf3ac289b21
ToppCell	NS-moderate-d_07-13-Myeloid-pDC\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	BLK FUT7 PACSIN1	6.47e-04	168	45	3	d03e91f0e0518b33555c0ec98124fc5ed0f11be5
ToppCell	facs-Limb_Muscle-forelimb_and_hindlimb-18m-Lymphocytic-T_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCED1A TMEM131L PACSIN1	6.47e-04	168	45	3	182f08106ac65ea501e2fb9139d3b44b7c4662c9
ToppCell	3'_v3-blood-Lymphocytic_B-ABC_aged-B_memory\|blood / Manually curated celltypes from each tissue	BLK PROB1 FUT7	6.47e-04	168	45	3	2ce1a30feb2704a9516d1dab161a26cb0555abb5
ToppCell	356C-Epithelial_cells-Epithelial-D_(AT2)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	FHL1 PTCD1 SLX4	6.58e-04	169	45	3	f982f2e0d341fa27229f443ebe5c0e4a9e63bda6
ToppCell	metastatic_Lymph_Node-T/NK_cells-Exhausted_Tfh\|T/NK_cells / Location, Cell class and cell subclass	CSRNP1 PROB1 RYR2	6.58e-04	169	45	3	3d48acea7482bbe5bb9da4c3af5f9b0c9800122f
ToppCell	metastatic_Brain-B_lymphocytes-GrB-secreting_B_cells\|metastatic_Brain / Location, Cell class and cell subclass	BLK FUT7 PACSIN1	6.58e-04	169	45	3	71f6761b9927f352e0ccc221ca373319915f4184
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FHL1 FOXR2 CFB	6.58e-04	169	45	3	8bfa2d3bb541d02f55d7c95b8fd156c8403befca
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m-Mesenchymal\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FHL1 FOXR2 CFB	6.58e-04	169	45	3	bb43abad2c049b7f4d307737347290e01b3339a3
ToppCell	356C-Epithelial_cells-Epithelial-D_(AT2)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	FHL1 PTCD1 SLX4	6.58e-04	169	45	3	818ab7a6fd1940a22d3bd99fe15f0af888af6b3e
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FHL1 FOXR2 CFB	6.58e-04	169	45	3	5f18e3f40a5b1b167903f37516ec8181e889c7c5
ToppCell	B_cell\|World / lung cells shred on cell class, cell subclass, sample id	BLK FUT7 PACSIN1	6.69e-04	170	45	3	cec4090ba6a9c934d5f6f9e4aa7823f3713319b7
ToppCell	COVID-19-Heart-CM_+_Macrophage\|COVID-19 / Disease (COVID-19 only), tissue and cell type	MYOCD FHL1 RYR2	6.69e-04	170	45	3	3f15242a1d3e4e9871d9170b2ef05842fb609c29
ToppCell	Pericytes-Donor_02\|World / lung cells shred on cell class, cell subclass, sample id	MYOCD ITGA7 RYR2	6.81e-04	171	45	3	bbc8d9fc83d37c9250345b1e76776610799de9ae
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic-Plasmacytoid_Dendritic_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	BLK FUT7 PACSIN1	6.81e-04	171	45	3	39c8ae139e449217091e1481eb5e2aafb8f69a1c
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MYOCD ITGA7 RYR2	6.81e-04	171	45	3	4ede831aed364cb5271f49a8b09bb6d0452f9b35
ToppCell	facs-Lung-nan-3m-Lymphocytic-B_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BLK TMEM131L BCAR3	6.81e-04	171	45	3	a31c23406cf6d6a17358a8fb41d392a7fb0306e0
ToppCell	facs-Lung-nan-3m-Lymphocytic-B_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BLK TMEM131L BCAR3	6.81e-04	171	45	3	43d8fd9b9546e84a652564fe96b514b34b06262b
ToppCell	Adult-Mesenchymal-vascular_smooth_muscle_cell\|Adult / Lineage, Cell type, age group and donor	MYOCD ITGA7 RYR2	6.92e-04	172	45	3	c62cad0f4212d1e9ea1ec3143ad3c4e06aff0ebf
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-ASMC\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MYOCD ITGA7 RYR2	7.04e-04	173	45	3	cb6389536195443633adb06e5f1b7483530773d1
ToppCell	Adult-Mesenchymal-airway_smooth_muscle_cell\|Adult / Lineage, Cell type, age group and donor	MYOCD ITGA7 RYR2	7.04e-04	173	45	3	a5331721bd9f9a66530dd4ffe28cb3a5a8cad8fc
ToppCell	Children_(3_yrs)-Mesenchymal-vascular_smooth_muscle_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	MYOCD ITGA7 RYR2	7.04e-04	173	45	3	5416b092321c7d9b63f0418c60f2402a138355bf
ToppCell	356C-Myeloid-Macrophage-SPP1+_Macrophage_4\|356C / Donor, Lineage, Cell class and subclass (all cells)	PRDM7 SLX4 PRSS36	7.16e-04	174	45	3	75b3a852140fb726025c3c987143d67944afde2d
ToppCell	Fetal_29-31_weeks-Mesenchymal-vascular_smooth_muscle_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	MYOCD ITGA7 RYR2	7.16e-04	174	45	3	015d3742d3d79a57413a333f00ef2d380a9848dd
Disease	Bartter disease type 3 (implicated_via_orthology)	CLCNKA CLCNKB	2.17e-06	2	44	2	DOID:0110144 (implicated_via_orthology)
Disease	Bartter disease type 4b (is_implicated_in)	CLCNKA CLCNKB	2.17e-06	2	44	2	DOID:0110146 (is_implicated_in)
Disease	Bartter disease type 4B	CLCNKA CLCNKB	2.17e-06	2	44	2	cv:C4310805
Disease	BARTTER SYNDROME, TYPE 4B, NEONATAL, WITH SENSORINEURAL DEAFNESS	CLCNKA CLCNKB	2.17e-06	2	44	2	613090
Disease	Bartter disease (implicated_via_orthology)	CLCNKA CLCNKB	2.17e-06	2	44	2	DOID:445 (implicated_via_orthology)
Disease	BARTTER SYNDROME, TYPE 4B	CLCNKA CLCNKB	2.17e-06	2	44	2	C2751312
Disease	BARTTER SYNDROME, TYPE 4B, NEONATAL, WITH SENSORINEURAL DEAFNESS	CLCNKA CLCNKB	2.17e-06	2	44	2	C4310805
Disease	Bartter syndrome	CLCNKA CLCNKB	3.25e-05	6	44	2	cv:C0004775
Disease	myopathy (implicated_via_orthology)	FHL1 CLCNKA CLCNKB	5.11e-05	48	44	3	DOID:423 (implicated_via_orthology)
Disease	nephrogenic diabetes insipidus (implicated_via_orthology)	CLCNKA CLCNKB	9.71e-05	10	44	2	DOID:12387 (implicated_via_orthology)
Disease	systemic scleroderma	BLK TULP4 ARHGAP31	2.81e-04	85	44	3	EFO_0000717
Disease	Tourette syndrome, schizophrenia	DNAH10 DNAH10OS	3.27e-04	18	44	2	EFO_0004895, MONDO_0005090
Disease	aortic measurement	BLK FHL1 RYR2 SMG6	5.31e-04	251	44	4	EFO_0020865
Disease	candidiasis (implicated_via_orthology)	FUT4 FUT7	1.98e-03	44	44	2	DOID:1508 (implicated_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
GDQWPWEARELMPQD	ERV3-1	301	Q14264
DWMLGYPDTWNPPPT	SMG6	1031	Q86US8
TPLPDNVEEPWRMMW	AADAC	21	P22760
PWEPAAAQMEKGQWD	BCAR3	486	O75815
RCMVPESEWAPWQPQ	DNAH10OS	96	P0CZ25
PTSQRPSWWPFEMSP	ACBD5	491	Q5T8D3
PEEMQFGWWRIIDPE	BAZ2B	1711	Q9UIF8
EGPWPADAPSWMNKP	FAM220A	36	Q7Z4H9
TEGPWPADAPSWMNK	FAM220BP	36	B1ANY3
QNWLAEFNMWLPPPE	RAD54L2	341	Q9Y4B4
MSWPDDVPPEGWNRT	CFB	366	P00751
MRATWQPAPFLPWDQ	PSMG3-AS1	11	Q96PY0
RAWDSEEEGPWDQMP	CSRNP1	41	Q96S65
RPPGQRWVWMNFESP	FUT4	286	P22083
PTPQPESQESMQWQW	CFAP65	1816	Q6ZU64
QSEEPGWAWSPQDPR	LBHD1	126	Q9BQE6
RGYPPDPWIEDWAEM	PCED1A	276	Q9H1Q7
PRGQPWVWASMESPS	FUT7	111	Q11130
PWETMEWLDLTPPNS	MYOCD	886	Q8IZQ8
PMNWPQFEEWNPDLP	PACSIN1	296	Q9BY11
SDEEWTPRQQVKPPW	PRDM9	91	Q9NQV7
PGAWPWEAQVMVPGS	PRSS36	331	Q5K4E3
APVWWPMKDNPGTTT	FHL1	301	Q13642
VRPAPQNPWAQDEWE	BLK	221	P51451
GPDYEPNLWMWVNPN	FOXR1	46	Q6PIV2
WNVSLPPTAGPEMWT	ABCA2	1611	Q9BZC7
GPPCEPNLWMWVDPN	FOXR2	71	Q6PJQ5
EPWWTLPENFHSPMV	KHDC1L	11	Q5JSQ8
QEPGERQEPSMSWWP	ITGA7	966	Q13683
MDLWNWDEASPQEVP	ETV2	1	O00321
VNNTGIDWFMPWPPQ	DNAH10	2951	Q8IVF4
MSRWWEHGPENNPER	RYR2	3246	Q92736
MSGPIDNAIDWNPDW	POLR3GL	96	Q9BT43
QSTWNTPPNMPAAWG	TMEM131L	1496	A2VDJ0
SDEEWTPRQQVKPPW	PRDM7	91	Q9NQW5
PGEATAVEWGPNTWM	SIGMAR1	156	Q99720
WWSHDPGVRPEETMP	TEX49	86	A0A1B0GTD5
IGTWGPSPQETWDPM	PROB1	511	E7EW31
WDVWDGEEQRPPETP	SLX4	1511	Q8IY92
SWALMTQNSSPPWPE	CLCNKA	366	P51800
SWALMTQNSSPPWPE	CLCNKB	366	P51801
PYQWDPMLGEDVWVP	TULP4	1121	Q9NRJ4
DNWPMDWEEEQVSSP	UBL3	41	O95164
GLEMVEPWEEPQWVT	ARHGAP31	901	Q2M1Z3
WMKRFNPPADAWPQE	DCT	406	P40126
WLTVMPAEETPHPWQ	PTCD1	661	O75127