Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionserine-type endopeptidase activity

PRSS55 TPSAB1 DPP4 CTRL PRSS41 CTSV ST14 TPSB2 PRSS21

6.79e-11190389GO:0004252
GeneOntologyMolecularFunctionserine-type peptidase activity

PRSS55 TPSAB1 DPP4 CTRL PRSS41 CTSV ST14 TPSB2 PRSS21

1.46e-10207389GO:0008236
GeneOntologyMolecularFunctionserine hydrolase activity

PRSS55 TPSAB1 DPP4 CTRL PRSS41 CTSV ST14 TPSB2 PRSS21

1.81e-10212389GO:0017171
GeneOntologyMolecularFunctionendopeptidase activity

PRSS55 TPSAB1 DPP4 CTRL PRSS41 CTSV ST14 TPSB2 PRSS21

8.59e-08430389GO:0004175
GeneOntologyMolecularFunctionpeptidase activity

PRSS55 TPSAB1 DPP4 CTRL PRSS41 CTSV ST14 TPSB2 PRSS21

2.86e-06654389GO:0008233
GeneOntologyMolecularFunctionbeta-galactosidase activity

GLB1 GLB1L

3.51e-055382GO:0004565
GeneOntologyMolecularFunctiongalactosidase activity

GLB1 GLB1L

7.36e-057382GO:0015925
GeneOntologyMolecularFunctioncysteine-type endopeptidase activator activity involved in apoptotic process

CTSV APAF1

1.39e-0329382GO:0008656
GeneOntologyMolecularFunctionpeptidase activator activity involved in apoptotic process

CTSV APAF1

1.69e-0332382GO:0016505
DomainTRYPSIN_SER

PRSS55 TPSAB1 CTRL PRSS41 ST14 TPSB2 PRSS21

3.55e-1090367IPR033116
DomainTRYPSIN_HIS

PRSS55 TPSAB1 CTRL PRSS41 ST14 TPSB2 PRSS21

9.24e-10103367IPR018114
DomainTRYPSIN_SER

PRSS55 TPSAB1 CTRL PRSS41 ST14 TPSB2 PRSS21

1.13e-09106367PS00135
DomainTRYPSIN_HIS

PRSS55 TPSAB1 CTRL PRSS41 ST14 TPSB2 PRSS21

1.21e-09107367PS00134
DomainPeptidase_S1A

PRSS55 TPSAB1 CTRL PRSS41 ST14 TPSB2 PRSS21

1.78e-09113367IPR001314
DomainTRYPSIN_DOM

PRSS55 TPSAB1 CTRL PRSS41 ST14 TPSB2 PRSS21

2.01e-09115367PS50240
DomainTryp_SPc

PRSS55 TPSAB1 CTRL PRSS41 ST14 TPSB2 PRSS21

2.27e-09117367SM00020
DomainTrypsin

PRSS55 TPSAB1 CTRL PRSS41 ST14 TPSB2 PRSS21

2.87e-09121367PF00089
DomainTrypsin_dom

PRSS55 TPSAB1 CTRL PRSS41 ST14 TPSB2 PRSS21

2.87e-09121367IPR001254
DomainPeptidase_S1_PA

PRSS55 TPSAB1 CTRL PRSS41 ST14 TPSB2 PRSS21

3.22e-09123367IPR009003
DomainGalactose-bd-like

CNTNAP3 CNTNAP4 CNTNAP3B HERC2 GLB1 GLB1L

2.38e-0894366IPR008979
Domain-

CNTNAP3 CNTNAP4 HERC2 GLB1 GLB1L

2.72e-07733652.60.120.260
DomainFibrinogen_a/b/g_C_dom

CNTNAP3 CNTNAP4 CNTNAP3B FGL2

4.02e-0732364IPR002181
DomainFIBRINOGEN_C_2

CNTNAP3 CNTNAP4 CNTNAP3B FGL2

4.02e-0732364PS51406
DomainFIBRINOGEN_C_1

CNTNAP3 CNTNAP4 CNTNAP3B FGL2

4.02e-0732364PS00514
DomainFA58C

CNTNAP3 CNTNAP4 CNTNAP3B

8.54e-0621363SM00231
DomainFA58C_3

CNTNAP3 CNTNAP4 CNTNAP3B

8.54e-0621363PS50022
DomainFA58C_1

CNTNAP3 CNTNAP4 CNTNAP3B

8.54e-0621363PS01285
DomainFA58C_2

CNTNAP3 CNTNAP4 CNTNAP3B

8.54e-0621363PS01286
DomainF5_F8_type_C

CNTNAP3 CNTNAP4 CNTNAP3B

1.29e-0524363PF00754
DomainFA58C

CNTNAP3 CNTNAP4 CNTNAP3B

1.29e-0524363IPR000421
DomainB-gal_1-like

GLB1 GLB1L

2.16e-054362IPR026283
DomainGLYCOSYL_HYDROL_F35

GLB1 GLB1L

2.16e-054362PS01182
DomainGlyco_hydro_35

GLB1 GLB1L

2.16e-054362PF01301
DomainGly_Hdrlase_35_cat

GLB1 GLB1L

2.16e-054362IPR031330
DomainGlycoside_Hdrlase_35

GLB1 GLB1L

2.16e-054362IPR001944
DomainFBG

CNTNAP3 CNTNAP4 FGL2

2.32e-0529363SM00186
Domain-

CNTNAP3 CNTNAP4 FGL2

2.58e-05303633.90.215.10
DomainFibrinogen_a/b/g_C_1

CNTNAP3 CNTNAP4 FGL2

2.58e-0530363IPR014716
DomainLAM_G_DOMAIN

CNTNAP3 CNTNAP4 CNTNAP3B

5.30e-0538363PS50025
DomainLaminin_G_2

CNTNAP3 CNTNAP4 CNTNAP3B

6.19e-0540363PF02210
DomainLamG

CNTNAP3 CNTNAP4 CNTNAP3B

8.25e-0544363SM00282
DomainLaminin_G

CNTNAP3 CNTNAP4 CNTNAP3B

1.89e-0458363IPR001791
DomainConA-like_dom

CNTNAP3 CNTNAP4 CNTNAP3B TRIM7

8.07e-04219364IPR013320
Domain-

GLB1 GLB1L

2.07e-03353623.20.20.80
DomainGlyco_hydro_catalytic_dom

GLB1 GLB1L

2.43e-0338362IPR013781
DomainSH3_1

NEB SH3PXD2A SKAP1

3.84e-03164363PF00018
DomainGlycoside_hydrolase_SF

GLB1 GLB1L

4.68e-0353362IPR017853
DomainSH3

NEB SH3PXD2A SKAP1

8.22e-03216363PS50002
DomainSH3

NEB SH3PXD2A SKAP1

8.22e-03216363SM00326
DomainSH3_domain

NEB SH3PXD2A SKAP1

8.65e-03220363IPR001452
DomainEGF_3

CNTNAP3 CNTNAP4 CNTNAP3B

1.03e-02235363PS50026
DomainEGF

CNTNAP3 CNTNAP4 CNTNAP3B

1.03e-02235363SM00181
DomainEGF-like_dom

CNTNAP3 CNTNAP4 CNTNAP3B

1.21e-02249363IPR000742
DomainEGF_1

CNTNAP3 CNTNAP4 CNTNAP3B

1.29e-02255363PS00022
Pubmed

Mouse chromosome 17A3.3 contains 13 genes that encode functional tryptic-like serine proteases with distinct tissue and cell expression patterns.

TPSAB1 PRSS41 PRSS21

1.44e-071038314583634
Pubmed

Cell adhesion molecule contactin-associated protein 3 is expressed in the mouse basal ganglia during early postnatal stages.

CNTNAP3 CNTNAP4 CNTNAP3B

8.10e-071738326389685
Pubmed

The critical role of ASD-related gene CNTNAP3 in regulating synaptic development and social behavior in mice.

CNTNAP3 CNTNAP3B

1.16e-06238231150793
Pubmed

The structure of the human betaII-tryptase tetramer: fo(u)r better or worse.

TPSAB1 TPSB2

1.16e-06238210500112
Pubmed

Characterization of a tryptase mRNA expressed in the human basophil cell line KU812.

TPSAB1 TPSB2

1.16e-0623828434231
Pubmed

Cloning and characterization of a second complementary DNA for human tryptase.

TPSAB1 TPSB2

1.16e-0623822203827
Pubmed

Characterization of two highly polymorphic human tryptase loci and comparison with a newly discovered monkey tryptase ortholog.

TPSAB1 TPSB2

1.16e-06238210898108
Pubmed

Caspr3-Deficient Mice Exhibit Low Motor Learning during the Early Phase of the Accelerated Rotarod Task.

CNTNAP3 CNTNAP3B

1.16e-06238226807827
Pubmed

Human beta-tryptase is a ring-like tetramer with active sites facing a central pore.

TPSAB1 TPSB2

1.16e-0623829521329
Pubmed

Human mast cell tryptase: multiple cDNAs and genes reveal a multigene serine protease family.

TPSAB1 TPSB2

1.16e-0623822187193
Pubmed

Structural requirements and mechanism for heparin-dependent activation and tetramerization of human betaI- and betaII-tryptase.

TPSAB1 TPSB2

1.16e-06238215567416
Pubmed

Human tryptases alpha and beta/II are functionally distinct due, in part, to a single amino acid difference in one of the surface loops that forms the substrate-binding cleft.

TPSAB1 TPSB2

1.16e-06238210391906
Pubmed

The human mast cell tryptase tetramer: a fascinating riddle solved by structure.

TPSAB1 TPSB2

1.16e-06238210708850
Pubmed

Tryptase haplotype in mastocytosis: relationship to disease variant and diagnostic utility of total tryptase levels.

TPSAB1 TPSB2

1.16e-06238217449330
Pubmed

Impact of naturally forming human α/β-tryptase heterotetramers in the pathogenesis of hereditary α-tryptasemia.

TPSAB1 TPSB2

1.16e-06238231337736
Pubmed

Characterization of genes encoding known and novel human mast cell tryptases on chromosome 16p13.3.

TPSAB1 TPSB2

3.48e-0633829920877
Pubmed

Complete loss of function of the ubiquitin ligase HERC2 causes a severe neurodevelopmental phenotype.

HERC2 BRCA1

3.48e-06338227759030
Pubmed

TUSC4 functions as a tumor suppressor by regulating BRCA1 stability.

HERC2 BRCA1

3.48e-06338225480944
Pubmed

Human subjects are protected from mast cell tryptase deficiency despite frequent inheritance of loss-of-function mutations.

TPSAB1 TPSB2

3.48e-06338219748655
Pubmed

HERC2 is an E3 ligase that targets BRCA1 for degradation.

HERC2 BRCA1

3.48e-06338220631078
Pubmed

Caspr3 and caspr4, two novel members of the caspr family are expressed in the nervous system and interact with PDZ domains.

CNTNAP3 CNTNAP4

1.16e-05538212093160
Pubmed

Characterization of human gamma-tryptases, novel members of the chromosome 16p mast cell tryptase and prostasin gene families.

TPSAB1 TPSB2

1.16e-05538210843716
Pubmed

Large-scale investigation of genomic markers for severe periodontitis.

DPP4 FGL2

1.16e-05538215490304
Pubmed

Nucleolar exit of RNF8 and BRCA1 in response to DNA damage.

HERC2 BRCA1

1.16e-05538222814251
Pubmed

New developments in the genetics and activation of mast cell proteases.

TPSAB1 TPSB2

1.74e-05638212217407
Pubmed

In trans neuregulin3-Caspr3 interaction controls DA axonal bassoon cluster development.

CNTNAP3 CNTNAP3B

1.74e-05638234143959
Pubmed

Activity-dependent and graded BACE1 expression in the olfactory epithelium is mediated by the retinoic acid metabolizing enzyme CYP26B1.

KIRREL2 ADCY3

3.24e-05838224797530
Pubmed

Ankyrin-based subcellular gradient of neurofascin, an immunoglobulin family protein, directs GABAergic innervation at purkinje axon initial segment.

SLC6A1 NFASC

4.16e-05938215479642
Pubmed

Conserved molecular signatures of neurogenesis in the hippocampal subgranular zone of rodents and primates.

SLC6A1 CNTNAP4 ACSBG1 CTSV PTPRZ1

5.38e-0537638524154525
Pubmed

Cloning and chromosomal mapping of mouse ADAM11, ADAM22 and ADAM23.

BRCA1 FGL2

9.00e-051338210433968
Pubmed

β3GnT2 maintains adenylyl cyclase-3 signaling and axon guidance molecule expression in the olfactory epithelium.

KIRREL2 ADCY3

1.05e-041438221525298
Pubmed

Olig2 regulates terminal differentiation and maturation of peripheral olfactory sensory neurons.

KIRREL2 ADCY3

1.76e-041838231758234
Pubmed

Local protease signaling contributes to neural tube closure in the mouse embryo.

CTRL ST14

2.18e-042038220152175
Pubmed

Regulation of cell surface protease matriptase by HAI2 is essential for placental development, neural tube closure and embryonic survival in mice.

CTRL ST14

2.41e-042138219592578
Pubmed

Uncx regulates proliferation of neural progenitor cells and neuronal survival in the olfactory epithelium.

KIRREL2 ADCY3

2.41e-042138220692344
Pubmed

FoxP1 orchestration of ASD-relevant signaling pathways in the striatum.

CNTNAP3 CNTNAP3B

2.65e-042238226494785
Pubmed

Identification by proximity labeling of novel lipidic and proteinaceous potential partners of the dopamine transporter.

NFASC HERC2

4.01e-042738234709416
Pubmed

Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.

TPSAB1 NFASC BRCA1 TPSB2

4.50e-0432938417474147
Pubmed

Zfhx3 is required for the differentiation of late born D1-type medium spiny neurons.

CNTNAP3 CNTNAP3B

4.63e-042938231491374
Pubmed

HERC2 Facilitates BLM and WRN Helicase Complex Interaction with RPA to Suppress G-Quadruplex DNA.

HERC2 BRCA1

5.30e-043138230279242
Pubmed

Developmental changes of glycosphingolipids and expression of glycogenes in mouse brains.

GLB1 B3GAT2

5.65e-043238217883393
Pubmed

Goofy coordinates the acuity of olfactory signaling.

KIRREL2 ADCY3

6.38e-043438223926254
Pubmed

Role of ADTRP (Androgen-Dependent Tissue Factor Pathway Inhibitor Regulating Protein) in Vascular Development and Function.

TPSAB1 DPP4

7.15e-043638230571485
Pubmed

Endothelin-2 deficiency causes growth retardation, hypothermia, and emphysema in mice.

DPP4 SLC9A2

9.28e-044138223676500
Cytoband16p13.3

TPSAB1 PRSS41 TPSB2 PRSS21

4.99e-0524438416p13.3
CytobandEnsembl 112 genes in cytogenetic band chr16p13

TPSAB1 PRSS41 TPSB2 PRSS21

4.20e-04426384chr16p13
GeneFamilyProteases, serine

PRSS55 PRSS41 ST14 PRSS21

1.60e-0663254738
GeneFamilySolute carriers

SLC6A1 SLC8A2 SLC9A2

1.67e-02395253752
GeneFamilyFibronectin type III domain containing

NFASC PTPRZ1

2.04e-02160252555
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

NFASC KIRREL2

2.07e-02161252593
CoexpressionGSE20366_TREG_VS_NAIVE_CD4_TCELL_DEC205_CONVERSION_UP

NEB ACSBG1 CTSV SH3PXD2A FGL2

1.01e-05200385M4332
CoexpressionDESCARTES_ORGANOGENESIS_INHIBITORY_INTERNEURONS

CNTNAP3 SLC6A1 CNTNAP3B

1.11e-0530383MM3663
CoexpressionAtlasProgenitor-Cell-Biology-Consortium_StemCell_fromBlastocyst-derived-humanEmbryonicStemCells_top-relative-expression-ranked_1000

ERVH48-1 SLC8A2 PMEL KIRREL2 ACSBG1 CTSV PTPRZ1 ST14 B3GAT2

3.10e-05993369PCBC_SC_blastocyst_1000
CoexpressionAtlasAravindRamakr_StemCell_from_inducedPluripotentialStemCells_derived from_from_fibroblast_top-relative-expression-ranked_1000_k-means-cluster#3

TPSAB1 ACSBG1 TPSB2

7.34e-0548363Arv_SC_fibroblast_1000_K3
CoexpressionAtlasgeo_heart_top-relative-expression-ranked_500_k-means-cluster#5

TPSAB1 TPSB2

7.78e-058362geo_heart_500_K5
CoexpressionAtlasAravindRamakr_StemCell-HD_top-relative-expression-ranked_1000_k-means-cluster#5

TPSAB1 ACSBG1 TPSB2

8.30e-0550363Arv_SC-HD_1000_K5
CoexpressionAtlasDevelopingKidney_e15.5_Proximal Tubules_emap-28005_k-means-cluster#4_top-relative-expression-ranked_200

DPP4 GLB1L TRIM7

8.81e-0551363gudmap_developingKidney_e15.5_Proximal Tubules_200_k4
CoexpressionAtlasalpha beta T cells, T.4.Sp.B16, 4+ 8- TCR+ 45+, B16 Melanoma Spleen, avg-2

PMEL NEB ACSBG1 SKAP1 FGL2

1.99e-04322365GSM605761_500
CoexpressionAtlasalpha beta T cells, T.4.Sp.B16, 4+ 8- TCR+ 45+, B16 Melanoma Spleen, avg-2

NEB SKAP1 FGL2

2.27e-0470363GSM605761_100
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CNTNAP3 PRSS55 CNTNAP4 CNTNAP3B DPP4

4.37e-07180385e8841ef1239f9ee73ac4f4e11faca0742694f368
ToppCellParenchymal-10x3prime_v2-Epithelial-Epi_airway_basal-Suprabasal|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

SLC6A1 SLC9A2 CTSV PTPRZ1 ST14

7.36e-07200385924eacea513dde8e3bd805a335bc4285647b800d
ToppCelldroplet-Kidney-nan-3m-Lymphocytic-CD45____NK_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BRCA1 ACSBG1 SKAP1 FGL2

1.11e-05163384a763c1632d6465a1e753bdc8eadaf819d2b09e5e
ToppCelldroplet-Kidney-nan-3m-Lymphocytic-NK_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BRCA1 ACSBG1 SKAP1 FGL2

1.11e-05163384eaed783eecd07aafa5af844b63c9d816b4da99e4
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-Treg-Treg_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NEB ACSBG1 PRSS41 SKAP1

1.22e-05167384eed22d1a17aab84dacb1a488528bae9389644cb9
ToppCellPND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-Treg|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NEB PRSS41 SKAP1 FGL2

1.25e-05168384c09aa66fd1374ecc4b4d4b56600a6f04aafa5be9
ToppCellMyeloid-Myeloid-D_(Mast_cell)|Myeloid / shred on cell class and cell subclass (v4)

TPSAB1 ST14 TPSB2 SKAP1

1.34e-051713845f1aafc4c55a9c6c3153430186a8a351425a3cb9
ToppCellfacs-Marrow-T-cells-3m-Lymphocytic-CD4-positive,_alpha-beta_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NEB ACSBG1 PRSS41 SKAP1

1.34e-051713848719a18c9e6b6f5d8ec4e937c2bda1e36441c9ec
ToppCellfacs-Marrow-T-cells-3m-Lymphocytic-BM_CD4_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NEB ACSBG1 PRSS41 SKAP1

1.34e-05171384f4cdd7862c8fe99ee765a2f3ed375b584f4976c5
ToppCell10x3'2.3-week_12-13-Myeloid_neutrophil-granulo-eo/baso/mast-eosinophil|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

TPSAB1 IGHV1-58 TPSB2 SKAP1

1.41e-051733841e4afa020fae682521335b440ccd33c16f37156f
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_2|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CNTNAP3 SLC6A1 CNTNAP3B B3GAT2

1.41e-0517338461907116a1460bc157ba73b5edd108db7dd5de4b
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-3_VIP_ZNF322P1|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SLC6A1 TPSAB1 SLC9A2 PTPRZ1

1.47e-051753849d09636a103daa8f622c3dbfd1f1536aaec3b6bb
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L3-4_PVALB_HOMER3|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CNTNAP3 SLC6A1 CNTNAP3B DPP4

1.54e-0517738491706bd0d4dda8d98843fb00b898d5aca4d66b64
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_2|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CNTNAP3 SLC6A1 CNTNAP3B B3GAT2

1.61e-051793843b0f8781232e1d42b6f8913bc989a14b3f978e79
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_2-Inh_L1-6_PVALB_SCUBE3_(Chandelier_1)|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CNTNAP3 SLC6A1 CNTNAP3B B3GAT2

1.68e-051813847704f236831cffe4f2a75d4c461eb88b4177e206
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_2|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CNTNAP3 SLC6A1 CNTNAP3B B3GAT2

1.68e-05181384153709b4dd3d81e09f251fa8765b58bed1932fda
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_VWA2|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CNTNAP3 PRSS55 CNTNAP4 CNTNAP3B

1.72e-0518238472e65a23cd36085bc880087d3cae92395de918a1
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CNTNAP3 PRSS55 CNTNAP4 CNTNAP3B

1.72e-0518238405c167158815bf25d509df59ab386e1990712765
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L4-6_SST_MTHFD2P6|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CNTNAP3 SLC6A1 CNTNAP3B SLC9A2

1.79e-0518438423515c28e1f42aab29cef9e5b4a7f45bda7f5520
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5_PVALB_CNTNAP3P2|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CNTNAP3 SLC6A1 CNTNAP3B PTPRZ1

1.91e-05187384d413fb4b1531b297af5012a392b88128510c2de8
ToppCellmetastatic_Lymph_Node-Myeloid_cells-Undetermined|Myeloid_cells / Location, Cell class and cell subclass

TPSAB1 KIRREL2 TPSB2 SKAP1

1.99e-05189384b46adb47768a7b6d801c457d7ba65508edfc36a5
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L4-6_SST_MTHFD2P6|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CNTNAP3 SLC6A1 SLC9A2 B3GAT2

1.99e-0518938406c44746fa4f02e6e2b3b635cdf2d8dfef3754d3
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CNTNAP3 SLC6A1 CNTNAP3B SLC9A2

2.03e-0519038426843ec1d19ac85a50990705353b802745d33e4d
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CNTNAP3 SLC6A1 CNTNAP3B PTPRZ1

2.03e-05190384305fbef734c350cfbf786ca7ff6e07093aab56ea
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Macroglial-astrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A1 KIRREL2 ACSBG1 PTPRZ1

2.08e-05191384fd345837bfc40d85256b9a7e4fd3343bcbfe0ae5
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SLC6A1 NFASC SH3PXD2A ADCY3

2.08e-0519138404c4d454b57e29a8d1dcdeb4678ce71bdc29b77b
ToppCellfacs-Brain_Non-Myeloid-Cortex_-18m-Macroglial-astrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A1 KIRREL2 ACSBG1 PTPRZ1

2.12e-05192384d2161842a38146261847fc9061ba9322e0f087e0
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CNTNAP3 SLC6A1 CNTNAP3B SLC9A2

2.16e-051933844979862c0c16e6b4baa4c79894f1d237c861f5a5
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L4-6_SST_MTHFD2P6|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CNTNAP3 SLC6A1 SLC9A2 B3GAT2

2.16e-051933842c15186d15545804cc262da9137ab825609d4b2c
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L4-6_SST_MTHFD2P6|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CNTNAP3 SLC6A1 CNTNAP3B B3GAT2

2.16e-051933848b77625bf3c87d39767fb391d1beaca4ab02342b
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CNTNAP3 SLC6A1 CNTNAP3B SLC9A2

2.21e-05194384e5990880961d2469759ce4b3b20ae93ace3ebd1f
ToppCelldistal-2-Hematologic-Basophil/Mast_1|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

TPSAB1 DPP4 TPSB2 SKAP1

2.30e-05196384ad21706a281f0b105eb3979e3e47fe0cec6c527f
ToppCellParenchymal-10x5prime-Stromal-Pericyte-Muscle_pericyte_systemic|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

SLC6A1 NFASC ADCY3 B3GAT2

2.39e-051983840dc5806714fb3d3983e9d19fa7a108e93a8090ed
ToppCellNeuronal-Inhibitory-iB-iB_2(PVALB)-SULF1--L4-6|Neuronal / cells hierarchy compared to all cells using T-Statistic

CNTNAP3 SLC6A1 CNTNAP3B PTPRZ1

2.48e-052003844a426ef88376d8bb2b9dc50aa06e7b9fc50ecc9c
ToppCellNeuronal-Inhibitory-iB-iB_2(PVALB)|Neuronal / cells hierarchy compared to all cells using T-Statistic

CNTNAP3 SLC6A1 CNTNAP3B PTPRZ1

2.48e-052003841276bfa911fddada4235e12e3081baa53164574b
ToppCellNeuronal-Inhibitory-iB-iB_3(PVALB-SST)-FRZB--L2-4|Neuronal / cells hierarchy compared to all cells using T-Statistic

CNTNAP3 SLC6A1 CNTNAP3B PTPRZ1

2.48e-052003845ec469267747dce3601c1d8ad01af89fa5b29acc
ToppCellNeuronal-Inhibitory-iB-iB_3(PVALB-SST)-FRZB|Neuronal / cells hierarchy compared to all cells using T-Statistic

CNTNAP3 SLC6A1 CNTNAP3B PTPRZ1

2.48e-05200384e79d93d55b25804f2608185168da472301b6ebca
ToppCellNeuronal-Inhibitory-iB-iB_2(PVALB)-SULF1|Neuronal / cells hierarchy compared to all cells using T-Statistic

CNTNAP3 SLC6A1 CNTNAP3B PTPRZ1

2.48e-05200384fbeee1c16ac0a7fe28d90491c8b079f21ce80bdc
ToppCellNeuronal-Inhibitory-iB-iB_2(PVALB)-SULF1-|Neuronal / cells hierarchy compared to all cells using T-Statistic

CNTNAP3 SLC6A1 CNTNAP3B PTPRZ1

2.48e-05200384c6eda342ea0cb37d71d89dbb8d11e819e0745172
ToppCellNeuronal-Inhibitory-iB-iB_3(PVALB-SST)-FRZB-|Neuronal / cells hierarchy compared to all cells using T-Statistic

CNTNAP3 SLC6A1 CNTNAP3B PTPRZ1

2.48e-05200384320d5a3a1e7da2fa8f1a164e29e180ec8ac9889c
ToppCellSubstantia_nigra-Macroglia-POLYDENDROCYTE-P2|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

PMEL BRCA1 ST14

5.05e-05843831f8b19b159f83655f66cb99f8d10d9a87c08f78f
ToppCellSubstantia_nigra-Macroglia-POLYDENDROCYTE-P2-Tnr-Polydendrocyte.Tnr.Bmp4_(Bmp4)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

PMEL BRCA1 ST14

5.05e-0584383c37e1170d39ad015f724e373a547ea5b6ba45a84
ToppCellSubstantia_nigra-Macroglia-POLYDENDROCYTE-P2-Tnr-Polydendrocyte.Tnr.Bmp4_(Bmp4)-|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

PMEL BRCA1 ST14

5.05e-05843837e4a76b65b0d34d9950f8b02590ff5a4b4534a27
ToppCellSubstantia_nigra-Macroglia-POLYDENDROCYTE-P2-Tnr|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

PMEL BRCA1 ST14

5.05e-0584383503490e9408d9638bcd089ef8ec0521924df9a5d
ToppCellEntopeduncular-Macroglia-POLYDENDROCYTE-P2-Tnr|Entopeduncular / BrainAtlas - Mouse McCarroll V32

PMEL BRCA1 ST14

6.21e-05903836adc78899a08d48da8ed4618ecf866c9ed9be059
ToppCellEntopeduncular-Macroglia-POLYDENDROCYTE-P2-Tnr-Polydendrocyte.Tnr.Bmp4_(Bmp4)|Entopeduncular / BrainAtlas - Mouse McCarroll V32

PMEL BRCA1 ST14

6.21e-0590383a74f8172780adc1410e36e2718412010ee0ebf1f
ToppCellEntopeduncular-Macroglia-POLYDENDROCYTE-P2-Tnr-Polydendrocyte.Tnr.Bmp4_(Bmp4)-|Entopeduncular / BrainAtlas - Mouse McCarroll V32

PMEL BRCA1 ST14

6.21e-0590383909ad62d175b657d8e541b0981ce8fed0ba7ed6c
ToppCellEntopeduncular-Macroglia-POLYDENDROCYTE-P2|Entopeduncular / BrainAtlas - Mouse McCarroll V32

PMEL BRCA1 ST14

6.21e-0590383936c5078677ec934f3049d8aa5a14d930aa2e6dc
ToppCellCOVID_vent-Lymphocytic-T_cell-CD4+_T_cell_(ISG_high)|COVID_vent / Disease condition, Lineage, Cell class and subclass

PRSS55 CNTNAP4 SLC8A2

1.68e-04126383a1ea8cf6b444a640544d204dfaf5ff219dc31aa9
ToppCellMyeloid-D_(Mast_cell)|World / shred on cell class and cell subclass (v4)

TPSAB1 TPSB2 SKAP1

1.85e-04130383574e262eb4ed2d69c3da68be061cebac9fefc29e
ToppCellLPS-antiTNF-Myeloid-Monocytes,_Macrophages-T-cells|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PTPRZ1 B3GAT2 TRIM7

2.11e-04136383186be8e1595608004b8216892cb9c7a7f31fbb4d
ToppCellHippocampus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Nxph3|Hippocampus / BrainAtlas - Mouse McCarroll V32

CNTNAP4 DPP4 SKAP1

2.20e-04138383b63e26afafbd2cdeed9c9451e6f530ab6295504c
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling-Cycling_Connecting_Tubule_Cell_S-high|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CNTNAP3B SLC9A2 BRCA1

2.25e-04139383c9bf98bed77415a1438f3f9e441a1346e75c26b0
ToppCellLymphoid-T_cells_(Cd8+_T_cell)|World / shred on cell class and cell subclass (v4)

PRSS41 SKAP1 FGL2

2.25e-04139383c85f50fb536f4df6fa4dbdebe48e1ecea1df1121
ToppCellLPS-antiTNF-Lymphocytic_NKT-T_cells-iNKT-MAIT|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DPP4 GLB1L SKAP1

2.30e-04140383a8f3b01d03ee0bf0e752327a98d6b9035930c2b0
ToppCellLPS-IL1RA-Hematopoietic_Mast|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DPP4 ACSBG1 SKAP1

2.39e-04142383f7d0d5ca9fc3dd929d4fdd59b71bfa623007e992
ToppCellLPS-IL1RA-Hematopoietic_Mast-Mast_cells|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DPP4 ACSBG1 SKAP1

2.39e-041423832a9a070e7c53ac593d46c6c5f6983f07d4413501
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ACSBG1 SKAP1 FGL2

2.50e-0414438346177f0d6117e701bda86a99ac2a1b0e7ed66177
ToppCellChildren_(3_yrs)-Immune-mast_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

TPSAB1 TPSB2 SKAP1

2.60e-04146383f7349d63bb47f1f22ced8ff514edc1c11bc782e7
ToppCellEntopeduncular-Macroglia-POLYDENDROCYTE|Entopeduncular / BrainAtlas - Mouse McCarroll V32

NFASC PMEL BRCA1

2.60e-04146383a317f14a1aab11ffcce65baeb1c475c04324315f
ToppCellLPS-antiTNF-Hematopoietic_Mast-Mast_cells|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DPP4 ACSBG1 SKAP1

2.76e-0414938359aa1f2a5cbeba64c4529fb05f544db17fd8b188
ToppCellLPS-antiTNF-Hematopoietic_Mast|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DPP4 ACSBG1 SKAP1

2.76e-041493831527cdd98a2734cbf8ce4c6170557280b71c55cb
ToppCellLPS_only-Hematopoietic_Mast-Mast_cells|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DPP4 ACSBG1 SKAP1

2.81e-041503837290e9a812b1b2f919e67ccde0acf52687ab138f
ToppCellLPS_only-Hematopoietic_Mast|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DPP4 ACSBG1 SKAP1

2.81e-041503832c5078a1f769ba8153dee756b53d28eb7b434a96
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Rxfp1_Prdm8|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CNTNAP3 CNTNAP4 B3GAT2

2.87e-04151383090b067873740c282865e2d02cf47d5cb3dd7607
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c11-GNLY|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

DPP4 ACSBG1 SKAP1

2.92e-04152383669d8f12fdb110ed72f4e5348b7b5350144a061c
ToppCellTracheal-10x3prime_v2-Immune_Myeloid-Mast_cell-Mast_cell|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

TPSAB1 TPSB2 SKAP1

2.92e-04152383321d322d58c12fd752de4e8ea873f3f367302813
ToppCellTracheal-10x3prime_v2-Immune_Myeloid-Mast_cell|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

TPSAB1 TPSB2 SKAP1

2.92e-04152383a4d50e9af02231c5573aee905cf0905391e6da34
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Degenerative_Podocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NFASC KIRREL2 CTSV

2.98e-04153383c1335e7d7407412431ed4d8c7dfcb2c6086d8483
ToppCellprimary_visual_cortex-Non-neuronal-astrocyte|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

KIRREL2 ACSBG1 PTPRZ1

2.98e-0415338395b28c5bd10ffb74c0993ebd565038b9818e4bd2
ToppCellprimary_visual_cortex-Non-neuronal-astrocyte-Astro|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

KIRREL2 ACSBG1 PTPRZ1

2.98e-04153383b09f8def40a1ea56722f3398f61a036667b61cd9
ToppCellChildren_(3_yrs)-Immune-mast_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

TPSAB1 TPSB2 SKAP1

2.98e-04153383d3fb83ca984c7583b1e51c364be6c7c17f67b048
ToppCellprimary_visual_cortex-Non-neuronal-astrocyte-Astro-Astro_Aqp4|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

KIRREL2 ACSBG1 PTPRZ1

2.98e-041533833ab9d55b3db51715c1d61eca142384195ce4b54f
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell_prolif|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CTSV B3GAT2 TPSB2

3.04e-041543831899138c096c08d8aee6b1970b7c0081e14c88a8
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Neural-neural_cell-Schwann_Cell_/_Neural-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ERVH48-1 SLC6A1 PTPRZ1

3.04e-0415438330cb4bb297fa815adb829f3b5cafca56fcbcb810
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Neural-neural_cell-Schwann_Cell_/_Neural|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ERVH48-1 SLC6A1 PTPRZ1

3.04e-04154383ade094e2947761a0a34daa8fcff3e9ea8437e4a5
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SLC6A1 SH3PXD2A ADCY3

3.04e-04154383b6e982e341c6cfb6ff80a318078fcb10c36d182f
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Neural|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ERVH48-1 SLC6A1 PTPRZ1

3.04e-0415438342bd8f88fd075a2d4edde394785decad88a2660a
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Neural-neural_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ERVH48-1 SLC6A1 PTPRZ1

3.04e-041543836425d9861148586466febd6eceae1b1f9b9a14c1
ToppCellfacs-Liver-Non-hepatocytes-3m-Lymphocytic-NK_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC9A2 SKAP1 FGL2

3.04e-0415438375eac6970259a6916fcfa6d3400509cfa2d98d9d
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SLC6A1 SH3PXD2A ADCY3

3.04e-04154383d76fd51a4587decbfe1dde1c8a9b880c5fa18e4a
ToppCellPND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ACSBG1 SKAP1 FGL2

3.04e-04154383d0a1ff02a7e91f6923aa85b65094f78e357e377d
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Granulocytic|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TPSAB1 ADCY3 TPSB2

3.10e-0415538351f6447945389649d99dcf7603b396195c631ead
ToppCellE18.5-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ACSBG1 SKAP1 FGL2

3.10e-04155383d8e9f355ce933f6383c3d1e35ff55235a95c7fcd
ToppCellAdult-Immune-mast_cell-D122|Adult / Lineage, Cell type, age group and donor

TPSAB1 TPSB2 SKAP1

3.10e-041553837c9de0591d1bf756b8e268b278bbe10bd5415dcd
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Granulocytic-Mast_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TPSAB1 ADCY3 TPSB2

3.10e-0415538323dc71cab28094ca0ac4d2baf4e24871ed107781
ToppCellCOVID-19-Mast_cells-Mast_cells|COVID-19 / group, cell type (main and fine annotations)

TPSAB1 TPSB2 SKAP1

3.16e-04156383bc10b94673184ef384c6665b16a1209a8975a4f1
ToppCell10x5'v1-week_12-13-Myeloid_DC-DC-DC2|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

SLC9A2 CTSV FGL2

3.16e-0415638303f3c5ffb27758fe63797143fcc938f9e8a4e10d
ToppCellCOVID-19-Mast_cells|COVID-19 / group, cell type (main and fine annotations)

TPSAB1 TPSB2 SKAP1

3.16e-04156383159504d43421ee83b9ab484816333ae549c9c2fd
ToppCell367C-Lymphocytic-CD4_T-cell-Treg_cell_3|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

NFASC ST14 FGL2

3.21e-041573836a0aa66964eecbbc232abf1d2e6c8422e4ce69d0
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Myh8_Fibin|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CNTNAP3 SLC6A1 CNTNAP4

3.21e-04157383741d79c10cb87fa7f14080c6fccb1553c3a20bad
ToppCellAdult-Immune-mast_cell-D231|Adult / Lineage, Cell type, age group and donor

TPSAB1 TPSB2 SKAP1

3.21e-041573834c63bb91f8708644e6ce2500072a4eeb8e1079dd
ToppCellChildren_(3_yrs)-Immune-mast_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

TPSAB1 TPSB2 SKAP1

3.21e-04157383ec185dbeabb67fd9ca85f71cab88463b60f9b1c1
ToppCellE18.5-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ACSBG1 SKAP1 FGL2

3.28e-041583835d926be5a0ebe8257cd552afa7844171f9ff01c0
ToppCell10x_3'_v3-thymus_(10x_3'_v3)-myeloid-myeloid_granulocytic-mast_cell|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

SLC6A1 TPSAB1 TPSB2

3.34e-04159383ecd1daa33549541aee3bf4e139ab6732efc8e74c
ToppCell10x_3'_v3-thymus_(10x_3'_v3)-myeloid-myeloid_granulocytic|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

SLC6A1 TPSAB1 TPSB2

3.34e-041593837b6370c9567da7d40541c6e243efa704ed7e90ae
ToppCellPND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ACSBG1 SKAP1 FGL2

3.34e-041593835c7a099aa84ecc62bf9b5e1609e5b6b77889f175
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma|TCGA-Pancreas / Sample_Type by Project: Shred V9

TPSAB1 TPSB2

3.39e-0432382b2d87153b4aefefd7b5e31ea67aa43e5f599e734
ToppCellTCGA-Pancreas-Primary_Tumor|TCGA-Pancreas / Sample_Type by Project: Shred V9

TPSAB1 TPSB2

3.39e-0432382f5bcaacbddfb85439ebf5908762bf39cb72b727c
ToppCellE16.5-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ACSBG1 SKAP1 FGL2

3.40e-04160383b2d8940ea8c068273b7da1589d3d6ae5110d8209
Drugbenzamidine

TPSAB1 CTRL ST14 TPSB2 FGL2 PRSS21

1.29e-07147376CID000002332
Drugbutter yellow

TPSAB1 DPP4 GLB1 TPSB2

1.57e-0730374CID000007340
DrugLeupeptin hydrochloride

TPSAB1 GLB1 CTRL CTSV ST14 TPSB2 PRSS21

2.69e-07276377CID000003910
DrugAC1NUP69

TPSAB1 CTRL TPSB2

4.70e-0710373CID005487154
DrugZ-ala-ala-lys-mna

TPSAB1 CTRL TPSB2

6.46e-0711373CID005486901
DrugAPMSF

TPSAB1 CTRL TPSB2 FGL2

1.09e-0648374CID000001719
DrugZ-ARR-AFC

TPSAB1 CTRL TPSB2

1.12e-0613373CID000125067
DrugNk3201

TPSAB1 CTRL TPSB2

1.12e-0613373CID000213050
Drugpyridindolol

GLB1 GLB1L

2.57e-062372CID005358591
Drugphenylmethylsulfonyl fluoride

TPSAB1 CTRL CTSV ST14 TPSB2 FGL2

3.86e-06263376CID000004784
DrugTLCK

TPSAB1 CTRL ADCY3 TPSB2 FGL2

5.50e-06158375CID000004427
DrugAC1NRA23

TPSAB1 CTRL CTSV TPSB2

5.93e-0673374CID005287657
Drugthymidine glycol monophosphate

TPSAB1 TPSB2

7.70e-063372CID000165415
DrugAC1L8VEV

TPSAB1 ADCY3 TPSB2

7.81e-0624373CID000433433
Drugdiisopropylfluorophosphate

TPSAB1 DPP4 CTRL ST14 TPSB2 FGL2

1.21e-05321376CID000005936
DrugAC1ND3F1

GLB1 GLB1L

1.54e-054372CID004568967
DrugBrunfelsamidine

TPSAB1 TPSB2

1.54e-054372CID005281683
DrugGPGR

TPSAB1 CTRL TPSB2

3.20e-0538373CID000485268
Drug2g6p

TPSAB1 ADCY3 TPSB2

3.20e-0538373CID002740174
Drugisocoumarin

TPSAB1 CTRL TPSB2

3.47e-0539373CID000068108
DrugNSC89634

TPSAB1 CTRL TPSB2

3.47e-0539373CID000070877
DrugDB04623

TPSAB1 TPSB2 PRSS21

3.47e-0539373CID005459358
Drugmaltos

TPSAB1 GLB1 ACSBG1 GLB1L TPSB2 FGL2

3.76e-05393376CID000000294
DrugAttpsa

TPSAB1 TPSB2

3.84e-056372CID005487511
DrugEHDA

BRCA1 GLB1

3.84e-056372CID006438592
DrugPhe-pro-arg

TPSAB1 TPSB2 FGL2

4.04e-0541373CID000133189
DrugNPGB

TPSAB1 CTRL TPSB2

4.04e-0541373CID000030744
DrugUDP-glucose

TPSAB1 GLB1 B3GAT2 TPSB2 TRIM7

4.74e-05247375CID000001166
Drugioxaglate

TPSAB1 TPSB2

5.37e-057372CID000003742
DrugTelebrix

TPSAB1 TPSB2

5.37e-057372CID000034536
Drugisobutyrate

TPSAB1 SLC9A2 TPSB2

7.80e-0551373CID000006590
Drugdaphnodorin C

TPSAB1 TPSB2

9.18e-059372CID000072428
DrugAC1LTNWX

TPSAB1 ADCY3 TPSB2

1.15e-0458373CID001536427
Drug1c5s

TPSAB1 TPSB2

1.15e-0410372CID000444753
Drug8-iso Misoprostol

KIRREL2 ADCY3 FGL2

1.40e-0462373CID004183806
Drugfenpropathrin

TPSAB1 TPSB2 FGL2

1.40e-0462373CID000047326
Drughexopyranos-3-ulose

GLB1 GLB1L

1.40e-0411372CID000000349
Drugpimaradiene

TPSAB1 TPSB2

1.40e-0411372CID000440909
Drugdaphnodorin A

TPSAB1 TPSB2

1.40e-0411372CID000072426
DrugAC1NSU64

TPSAB1 TPSB2

1.40e-0411372CID005316303
Drugmethylhistamine

TPSAB1 TPSB2

1.40e-0411372CID000000912
DrugN-acetyllactosamine

GLB1 PTPRZ1 GLB1L B3GAT2

1.42e-04164374CID000000245
Drugsodium cromoglycate

TPSAB1 TPSB2 PRSS21

1.47e-0463373CID000002881
DrugAC1Q6PMP

TPSAB1 CTRL ST14 TPSB2

1.60e-04169374CID000103535
Drugbis(5-amidino-2-benzimidazolyl)methane

TPSAB1 TPSB2

1.68e-0412372CID000002386
DrugNSC-648146

TPSAB1 TPSB2

1.68e-0412372CID000372649
DrugElocom

TPSAB1 TPSB2

1.68e-0412372CID000123620
Drug4-amidinophenylpyruvic acid

TPSAB1 TPSB2

1.68e-0412372CID000151496
DrugAC1MMOKY

GLB1 GLB1L

1.68e-0412372CID003289210
DrugTrichostatin A, Streptomyces sp.; Up 200; 1uM; MCF7; HT_HG-U133A

PMEL ACSBG1 CTSV APAF1

1.75e-041733745594_UP
DrugPCMB

GLB1 CTRL CTSV ADCY3

1.95e-04178374CID000001730
DrugGly-pro-mca

DPP4 CTRL

1.98e-0413372CID000125640
Drugtrichostatin A, Streptomyces sp.; Up 200; 1uM; MCF7; HT_HG-U133A

PMEL ACSBG1 CTSV APAF1

1.99e-041793745903_UP
DrugABPH

TPSAB1 TPSB2

2.31e-0414372CID000092377
DrugTrichostatin A, from Streptomyces sp.; Up 200; 0.1uM; HL60; HT_HG-U133A

NEB CTRL ACSBG1 GLB1L

2.40e-041883742370_UP
Drugnafamostat mesilate

TPSAB1 TPSB2 FGL2

2.66e-0477373CID000004413
DrugAC1L9K4M

TPSAB1 TPSB2

2.66e-0415372CID000446820
DrugFdTTP

TPSAB1 TPSB2

2.66e-0415372CID000162005
Drugchloromethyl

TPSAB1 CTRL TPSB2 FGL2

2.76e-04195374CID000007835
DrugZomepirac sodium salt [64092-48-4]; Up 200; 12.8uM; PC3; HT_HG-U133A

SLC9A2 SH3PXD2A GLB1L APAF1

2.82e-041963744479_UP
Drugglutathionesulfonic acid

SLC6A1 PMEL PRSS21

2.87e-0479373CID000003486
DrugPirenperone [ 75444-65-4]; Up 200; 10.2uM; HL60; HT_HG-U133A

PMEL CTRL GLB1L APAF1

2.87e-041973742455_UP
DrugNafronyl oxalate [3200-06-4]; Down 200; 8.4uM; MCF7; HT_HG-U133A

SLC9A2 UQCR11 ADCY3 ST14

2.87e-041973745287_DN
DrugRilmenidine hemifumarate [54187-04-1]; Down 200; 8.4uM; HL60; HT_HG-U133A

CTRL SH3PXD2A ST14 APAF1

2.87e-041973743133_DN
DrugDiflorasone Diacetate [33564-31-7]; Up 200; 8uM; PC3; HT_HG-U133A

DPP4 NEB GLB1L APAF1

2.87e-041973744077_UP
DrugCholecalciferol [67-97-0]; Up 200; 10.4uM; PC3; HT_HG-U133A

NEB CTRL SKAP1 APAF1

2.93e-041983746656_UP
DrugUngerine nitrate; Up 200; 10.2uM; HL60; HT_HG-U133A

ACSBG1 ST14 FGL2 APAF1

2.98e-041993742514_UP
DrugTMOF

DPP4 CTRL

3.04e-0416372CID005488810
DrugBM 17.0744

GLB1 GLB1L

3.04e-0416372CID009929731
Drug5 alpha-androstan-3-one

TPSAB1 TPSB2

3.04e-0416372CID000102028
Drug(E)-4-aminohex-4-enoic acid

TPSAB1 TPSB2

3.04e-0416372CID005288385
Drugthymidine glycol

TPSAB1 TPSB2

3.04e-0416372CID003035041
DrugN-acetyl-S-farnesyl-L-cysteine

TPSAB1 DPP4 TPSB2

3.20e-0482373CID000001994
DrugAC1NRATE

SLC6A1 DPP4 GLB1

3.32e-0483373CID005288086
DrugDB07356

TPSAB1 DPP4 TPSB2

3.32e-0483373CID011840917
Drug4-methylumbelliferyl

GLB1 CTRL ADCY3

3.32e-0483373CID000011833
Drug77 B

PMEL GLB1

3.44e-0417372CID005494400
Drugl 8 h

DPP4 GLB1

3.44e-0417372CID000151041
Drugmethylimidazoleacetic acid

TPSAB1 TPSB2

3.44e-0417372CID000075810
DrugH 17

TPSAB1 TPSB2

3.44e-0417372CID000476867
Drugazelaic bishydroxamic acid

GLB1 GLB1L

3.44e-0417372CID000065268
Drugl-alanyl-l-proline

TPSAB1 DPP4 TPSB2

3.81e-0487373CID000083525
DrugFp-O

TPSAB1 DPP4 TPSB2

3.81e-0487373CID000024267
Drug2-azetidinone

TPSAB1 TPSB2

3.87e-0418372CID000136721
DrugAC1L3X9U

DPP4 FGL2

3.87e-0418372CID000096811
Drugneotrehalose

TPSAB1 GLB1 TPSB2 APAF1

3.93e-04214374CID000001143
DrugA80a

TPSAB1 TPSB2

4.79e-0420372CID005487000
DrugNSC49103

TPSAB1 TPSB2

4.79e-0420372CID000005251
Drugatracurium besylate

TPSAB1 TPSB2

5.82e-0422372CID000047320
Drugboronic acids

DPP4 CTRL

5.82e-0422372CID000139619
Drug1-deoxynojirimycin hydrochloride

PMEL GLB1 GLB1L

6.07e-04102373CID000001374
DrugC12063

SLC6A1 PMEL GLB1 FGL2 APAF1

6.15e-04429375CID005282055
Drugtryptophanyl-5'AMP

TPSAB1 TPSB2

6.36e-0423372CID000446202
DrugAc-devd-amc

CTRL APAF1

6.36e-0423372CID000001992
DrugAC1L3W0F

ACSBG1 ST14

6.36e-0423372CID000123172
DrugKinetensin

TPSAB1 TPSB2

6.36e-0423372CID000147043
DrugPL 0

TPSAB1 TPSB2

6.93e-0424372CID000016157
DrugZ-Phe-Phe-CHN2

DPP4 CTSV

6.93e-0424372CID005486921
Drug2-vinyl benzaldehyde

TPSAB1 CTRL TPSB2

7.17e-04108373CID000039391
Drugethylnylestradiol

SLC6A1 BRCA1 GLB1 CTRL ACSBG1 ADCY3 FGL2 APAF1

7.52e-041251378CID000003285
Diseaseautosomal recessive intellectual developmental disorder (implicated_via_orthology)

CNTNAP3 CNTNAP4 CNTNAP3B

8.53e-088353DOID:0060308 (implicated_via_orthology)
Diseasetryptase beta-2 measurement

TPSAB1 TPSB2

4.89e-059352EFO_0008306
DiseaseSchizophrenia

SLC6A1 NFASC BRCA1 CTRL PTPRZ1 SH3PXD2A B3GAT2

6.78e-05883357C0036341
Diseasebrain ischemia (biomarker_via_orthology)

SLC8A2 CTSV APAF1

2.42e-04102353DOID:2316 (biomarker_via_orthology)
Diseaseurticaria

TPSAB1 TPSB2

2.56e-0420352EFO_0005531
Diseasemuscular atrophy (biomarker_via_orthology)

CTSV APAF1

5.44e-0429352DOID:767 (biomarker_via_orthology)
Diseaseovarian carcinoma

SLC6A1 BRCA1 PTPRZ1 SKAP1

5.52e-04321354EFO_0001075
Diseasetemporal lobe epilepsy (biomarker_via_orthology)

SLC6A1 PTPRZ1

6.22e-0431352DOID:3328 (biomarker_via_orthology)
Diseaseautism spectrum disorder (implicated_via_orthology)

CNTNAP3 CNTNAP4 CNTNAP3B

7.77e-04152353DOID:0060041 (implicated_via_orthology)
DiseaseBreast adenocarcinoma

HERC2 BRCA1

1.09e-0341352C0858252
DiseaseNeoplasm of uncertain or unknown behavior of breast

HERC2 BRCA1

1.09e-0341352C0496956
Diseaseforced expiratory volume

SLC6A1 SLC9A2 SH3PXD2A ADCY3 SKAP1

2.25e-03789355EFO_0004314
Diseasebasophil measurement

TPSAB1 TPSB2

2.32e-0360352EFO_0803539
DiseaseContact hypersensitivity

TPSAB1 GLB1

3.23e-0371352C0162351
DiseaseContact Dermatitis

TPSAB1 GLB1

3.23e-0371352C0011616
DiseaseMental Depression

SLC6A1 DPP4 BRCA1

3.37e-03254353C0011570
Diseaseasthma, response to diisocyanate

NFASC HERC2 SH3PXD2A

3.63e-03261353EFO_0006995, MONDO_0004979

Protein segments in the cluster

PeptideGeneStartEntry
GGYIKWWNVVTGESS

APAF1

1196

O14727
QKGNTWVLIGIVSWG

CTRL

221

P40313
GAGGWTPLVSNKYQW

CNTNAP3

66

Q9BZ76
NSWGPEWGSNGYVKI

CTSV

301

O60911
GAGGWSPLVSNKYQW

CNTNAP4

66

Q9C0A0
NWVPTAYTWGAVGAV

UQCR11

16

O14957
AYTWGAVGAVGLVWA

UQCR11

21

O14957
WIGWIVVGSGNTNYA

IGHV1-58

66

A0A0C4DH39
SLQEVIGWGLIGWKY

HERC2

421

O95714
IGWGLIGWKYYANVI

HERC2

426

O95714
IQFPGWTKGQVWING

GLB1

571

P16278
WTKGQVWINGFNLGR

GLB1

576

P16278
PWVWGGVGTLLYQLG

PCNX4

51

Q63HM2
NKRIAIWGWSYGGYV

DPP4

621

P27487
IGWSYTGALNQKNWG

PTPRZ1

36

P23471
DKDGLWYQVGIVSWG

PRSS41

256

Q7RTY9
WNNVTVWGSRYVVGQ

NFASC

776

O94856
GIAGGKWVVSYFWVT

BRCA1

1706

P38398
IGTDLVQWIWGGYSV

MT-CYB

156

P00156
LVENGKVVGWYTGWR

B3GAT2

221

Q9NPZ5
LYLPGWTKGQVWING

GLB1L

556

Q6UWU2
WTKGQVWINGFNLGR

GLB1L

561

Q6UWU2
VWINGFNLGRYWTKQ

GLB1L

566

Q6UWU2
IAAQIYDLWTGIQWG

ACSBG1

331

Q96GR2
LGGVLGQKRWQYDVW

ADCY3

421

O60266
QKYRGVRNGIFWGTW

FGL2

396

Q14314
ALGAYWGLVQWTKSG

KIRREL2

46

Q6UWL6
GAGGWTPLVSNKYQW

CNTNAP3B

66

Q96NU0
LWPQGGGWVQQVALK

RXFP4

331

Q8TDU9
KVNGTWLQAGVVSWG

TPSAB1

231

Q15661
KVNGTWLQAGVVSWG

TPSB2

231

P20231
YFCIWKGVGWTGKVV

SLC6A1

226

P30531
NYVFPKWGQGVGWLM

SLC6A1

526

P30531
YVWKTWGQYWQVLGG

PMEL

151

P40967
WGQYWQVLGGPVSGL

PMEL

156

P40967
GVWALQLNGGQYWAV

TRIM7

431

Q9C029
IGTIFWYAVVGTLWN

SLC9A2

166

Q9UBY0
WYAVVGTLWNSIGIG

SLC9A2

171

Q9UBY0
NSGGWWYVQIGEKEG

SH3PXD2A

481

Q5TCZ1
AGKAIWVTGWGHTQY

ST14

741

Q9Y5Y6
GKQWLCFTKIGQWGV

ERVH48-1

106

M5A8F1
GEKWYQVGIISWGKS

PRSS55

261

Q6UWB4
ILGNGYIALVNWIDW

TAS2R8

21

Q9NYW2
KNGLWYQIGVVSWGV

PRSS21

246

Q9Y6M0
YGWWVGELNSLVGIV

SKAP1

331

Q86WV1
GVAWSVAAVYWAVQG

SLC8A2

831

Q9UPR5
YNNWMKGIGWIPIGS

NEB

1196

P20929