Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	phosphotransferase activity, alcohol group as acceptor	AKT3 TRIO EGFR ADCK5 HKDC1 SRPK2 PFKFB3 STKLD1 WNK3	4.90e-05	709	49	9	GO:0016773
GeneOntologyMolecularFunction	transferase activity, transferring phosphorus-containing groups	AKT3 TRIO EGFR ADCK5 HKDC1 SRPK2 PFKFB3 STKLD1 POLK WNK3	7.71e-05	938	49	10	GO:0016772
GeneOntologyMolecularFunction	kinase activity	AKT3 TRIO EGFR ADCK5 HKDC1 SRPK2 PFKFB3 STKLD1 WNK3	8.71e-05	764	49	9	GO:0016301
GeneOntologyMolecularFunction	protein serine/threonine kinase activity	AKT3 TRIO EGFR ADCK5 SRPK2 STKLD1 WNK3	1.01e-04	446	49	7	GO:0004674
GeneOntologyMolecularFunction	structural constituent of postsynaptic actin cytoskeleton	POTEKP POTEI	3.20e-04	11	49	2	GO:0098973
GeneOntologyMolecularFunction	mRNA methyltransferase activity	RNMT PCIF1	4.52e-04	13	49	2	GO:0008174
GeneOntologyMolecularFunction	protein kinase activity	AKT3 TRIO EGFR ADCK5 SRPK2 STKLD1 WNK3	6.13e-04	600	49	7	GO:0004672
GeneOntologyMolecularFunction	carbohydrate kinase activity	HKDC1 PFKFB3	1.20e-03	21	49	2	GO:0019200
GeneOntologyMolecularFunction	structural constituent of postsynapse	POTEKP POTEI	2.79e-03	32	49	2	GO:0099186
Domain	-	KLHL8 KLHL18 KLHL31	4.19e-05	27	47	3	2.130.10.80
Domain	Gal_Oxidase_b-propeller	KLHL8 KLHL18 KLHL31	8.46e-05	34	47	3	IPR015916
Domain	PROTEIN_KINASE_ATP	AKT3 TRIO EGFR ADCK5 SRPK2 STKLD1 WNK3	1.39e-04	459	47	7	PS00107
Domain	BTB-kelch_protein	KLHL8 KLHL18 KLHL31	1.72e-04	43	47	3	IPR017096
Domain	PROTEIN_KINASE_DOM	AKT3 TRIO EGFR ADCK5 SRPK2 STKLD1 WNK3	2.16e-04	493	47	7	PS50011
Domain	Kinase-like_dom	AKT3 TRIO EGFR ADCK5 SRPK2 STKLD1 WNK3	3.83e-04	542	47	7	IPR011009
Domain	Kelch	KLHL8 KLHL18 KLHL31	4.18e-04	58	47	3	SM00612
Domain	Gal_Oxase/kelch_b-propeller	KLHL8 KLHL18 KLHL31	4.40e-04	59	47	3	IPR011043
Domain	BACK	KLHL8 KLHL18 KLHL31	4.62e-04	60	47	3	SM00875
Domain	BACK	KLHL8 KLHL18 KLHL31	4.85e-04	61	47	3	PF07707
Domain	BACK	KLHL8 KLHL18 KLHL31	4.85e-04	61	47	3	IPR011705
Domain	Kelch_1	KLHL8 KLHL18 KLHL31	7.26e-04	70	47	3	PF01344
Domain	Kelch_1	KLHL8 KLHL18 KLHL31	7.26e-04	70	47	3	IPR006652
Domain	Prot_kinase_dom	AKT3 TRIO EGFR SRPK2 STKLD1 WNK3	1.35e-03	489	47	6	IPR000719
Domain	Galactose-bd-like	PCSK7 PTPRU HECTD1	1.71e-03	94	47	3	IPR008979
Domain	HECT	WWP1 HECTD1	2.09e-03	27	47	2	PF00632
Domain	HECTc	WWP1 HECTD1	2.09e-03	27	47	2	SM00119
Domain	HECT_dom	WWP1 HECTD1	2.09e-03	27	47	2	IPR000569
Domain	HECT	WWP1 HECTD1	2.09e-03	27	47	2	PS50237
Domain	Pkinase	AKT3 TRIO SRPK2 STKLD1 WNK3	2.61e-03	381	47	5	PF00069
Domain	BTB	KLHL8 KLHL18 KLHL31	4.37e-03	131	47	3	PF00651
Domain	WW	WWP1 PCIF1	6.23e-03	47	47	2	PF00397
Domain	WW	WWP1 PCIF1	6.49e-03	48	47	2	SM00456
Domain	WW_DOMAIN_2	WWP1 PCIF1	7.31e-03	51	47	2	PS50020
Domain	WW_DOMAIN_1	WWP1 PCIF1	7.31e-03	51	47	2	PS01159
Domain	WW_dom	WWP1 PCIF1	7.59e-03	52	47	2	IPR001202
Domain	BTB	KLHL8 KLHL18 KLHL31	7.59e-03	160	47	3	PS50097
Domain	EGF_extracell	NTNG2 SVEP1	1.00e-02	60	47	2	IPR013111
Domain	EGF_2	NTNG2 SVEP1	1.00e-02	60	47	2	PF07974
Pathway	KEGG_MEDICUS_VARIANT_AMPLIFIED_EGFR_TO_PI3K_SIGNALING_PATHWAY	AKT3 EGFR	1.57e-04	8	34	2	M47394
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_EGFR_TO_PI3K_SIGNALING_PATHWAY	AKT3 EGFR	1.57e-04	8	34	2	M47395
Pathway	KEGG_MEDICUS_VARIANT_TGFA_OVEREXPRESSION_TO_PI3K_SIGNALING_PATHWAY	AKT3 EGFR	1.57e-04	8	34	2	M47482
Pathway	KEGG_MEDICUS_VARIANT_EGF_OVEREXPRESSION_TO_PI3K_SIGNALING_PATHWAY	AKT3 EGFR	1.57e-04	8	34	2	M47498
Pathway	KEGG_MEDICUS_REFERENCE_EGF_EGFR_PI3K_SIGNALING_PATHWAY	AKT3 EGFR	2.01e-04	9	34	2	M47392
Pathway	KEGG_MEDICUS_REFERENCE_TGFA_EGFR_PI3K_SIGNALING_PATHWAY	AKT3 EGFR	2.01e-04	9	34	2	M47481
Pathway	KEGG_MEDICUS_VARIANT_EGFR_OVEREXPRESSION_TO_PI3K_SIGNALING_PATHWAY	AKT3 EGFR	2.51e-04	10	34	2	M47400
Pathway	KEGG_MEDICUS_REFERENCE_EREG_EGFR_PI3K_SIGNALING_PATHWAY	AKT3 EGFR	3.06e-04	11	34	2	M47499
Pathway	KEGG_MEDICUS_REFERENCE_AREG_EGFR_PI3K_SIGNALING_PATHWAY	AKT3 EGFR	3.06e-04	11	34	2	M47501
Pathway	KEGG_MEDICUS_VARIANT_ERBB2_OVEREXPRESSION_TO_PI3K_SIGNALING_PATHWAY	AKT3 EGFR	3.67e-04	12	34	2	M47393
Pathway	WP_ENDOMETRIAL_CANCER	AKT3 EGFR POLK	4.61e-04	63	34	3	M39623
Pathway	KEGG_MEDICUS_REFERENCE_EGF_EGFR_PI3K_NFKB_SIGNALING_PATHWAY	AKT3 EGFR	5.05e-04	14	34	2	M47536
Pathway	KEGG_MEDICUS_REFERENCE_EGF_EGFR_RAS_PI3K_SIGNALING_PATHWAY	AKT3 EGFR	5.81e-04	15	34	2	M47389
Pathway	WP_RIOK1_AND_RIOK2_IN_EGFR_AND_PI3KMEDIATED_TUMORIGENESIS	AKT3 EGFR	5.81e-04	15	34	2	M48306
Pathway	WP_NONSMALL_CELL_LUNG_CANCER	AKT3 EGFR POLK	6.82e-04	72	34	3	M39738
Pathway	WP_INVOLVEMENT_OF_SECRETASE_IN_NEURODEGENERATIVE_DISEASES	AKT3 SRPK2	7.51e-04	17	34	2	M48086
Pubmed	Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.	AKT3 KMT2B EGFR WWP1 PCSK7 SRPK2 KLHL8 PTPRU KLHL18 WNK3	7.52e-08	730	50	10	34857952
Pubmed	Molecular basis for the differential use of glucose and glutamine in cell proliferation as revealed by synchronized HeLa cells.	GLS PFKFB3	2.03e-06	2	50	2	22106309
Pubmed	Epidermal growth factor receptor and podocin predict nephropathy progression in type 2 diabetic patients through interaction with the autophagy influencer ULK-1.	NPHS2 EGFR	6.07e-06	3	50	2	30545560
Pubmed	Molecular cloning and characterization of PTP pi, a novel receptor-like protein-tyrosine phosphatase.	EGFR PTPRU	6.07e-06	3	50	2	8870675
Pubmed	Proprotein convertase PC7 enhances the activation of the EGF receptor pathway through processing of the EGF precursor.	EGFR PCSK7	6.07e-06	3	50	2	21209099
Pubmed	Complex interactions between the angiotensin II type 1 receptor, the epidermal growth factor receptor and TRIO-dependent signaling partners.	TRIO EGFR	6.07e-06	3	50	2	33741329
Pubmed	MAT2B promotes proliferation and inhibits apoptosis in osteosarcoma by targeting epidermal growth factor receptor and proliferating cell nuclear antigen.	EGFR MAT2B	6.07e-06	3	50	2	30942439
Pubmed	New interaction partners for Nek4.1 and Nek4.2 isoforms: from the DNA damage response to RNA splicing.	SF3B3 TRIO CCT4 POTEKP PFKFB3 HECTD1 KLHL18	8.42e-06	513	50	7	25798074
Pubmed	The WW domain containing E3 ubiquitin protein ligase 1 upregulates ErbB2 and EGFR through RING finger protein 11.	EGFR WWP1	1.21e-05	4	50	2	18724389
Pubmed	TRIB3-EGFR interaction promotes lung cancer progression and defines a therapeutic target.	EGFR WWP1	1.21e-05	4	50	2	32694521
Pubmed	Update on the Kelch-like (KLHL) gene family.	KLHL8 KLHL18 KLHL31	2.87e-05	41	50	3	23676014
Pubmed	Duplication and extensive remodeling shaped POTE family genes encoding proteins containing ankyrin repeat and coiled coil domains.	POTEKP POTEI	7.25e-05	9	50	2	16364570
Pubmed	FBP WW domains and the Abl SH3 domain bind to a specific class of proline-rich ligands.	KMT2B SRPK2	9.05e-05	10	50	2	9171351
Pubmed	Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.	ABRA AKT3 MAT2B WWP1 SMC6 KLHL8 KLHL18	9.41e-05	750	50	7	11230166
Pubmed	Fluctuations in AKT and PTEN Activity Are Linked by the E3 Ubiquitin Ligase cCBL.	EGFR WWP1	1.10e-04	11	50	2	34831026
Pubmed	Identification of Smurf2 as a HIF-1α degrading E3 ubiquitin ligase.	KLHL8 HECTD1	1.32e-04	12	50	2	34611473
Pubmed	MKRN2 Physically Interacts with GLE1 to Regulate mRNA Export and Zebrafish Retinal Development.	NTNG2 TRIO EGFR WWP1 SRPK2	1.63e-04	358	50	5	32460013
Pubmed	A quantitative chaperone interaction network reveals the architecture of cellular protein homeostasis pathways.	AKT3 SF3B3 EGFR TMOD4 HECTD1	1.74e-04	363	50	5	25036637
Pubmed	Formin binding proteins bear WWP/WW domains that bind proline-rich peptides and functionally resemble SH3 domains.	KMT2B SRPK2	1.82e-04	14	50	2	8605874
Pubmed	Identification of a novel actin isoform in hepatocellular carcinoma.	POTEKP POTEI	2.10e-04	15	50	2	16824795
Pubmed	Cytoplasmic Metadherin (MTDH) provides survival advantage under conditions of stress by acting as RNA-binding protein.	KMT2B EGFR CCT4 PCCB	2.57e-04	214	50	4	22199357
Pubmed	A ubiquitin-based effector-to-inhibitor switch coordinates early brain, craniofacial, and skin development.	MIA3 KLHL8 KLHL18	2.72e-04	87	50	3	37495603
Pubmed	A cascading activity-based probe sequentially targets E1-E2-E3 ubiquitin enzymes.	WWP1 HECTD1 PCCB	2.81e-04	88	50	3	27182664
Pubmed	The ATG5 interactome links clathrin-mediated vesicular trafficking with the autophagosome assembly machinery.	MIA3 TRIO SRPK2 CCT4	3.38e-04	230	50	4	35449600
Pubmed	Toward a human blood serum proteome: analysis by multidimensional separation coupled with mass spectrometry.	EGFR ADGRB2	3.41e-04	19	50	2	12543931
Pubmed	Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.	LDHD MAT2B ADCK5 GLS PCCB NDUFS2 ZBED5	3.42e-04	926	50	7	20877624
Pubmed	The FNIP co-chaperones decelerate the Hsp90 chaperone cycle and enhance drug binding.	SF3B3 CCT4	4.18e-04	21	50	2	27353360
Pubmed	Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.	MIA3 TRIO EGFR GLS SRPK2 CCT4 KLHL8 HECTD1	4.88e-04	1297	50	8	33545068
Pubmed	A novel missense variant in CUL3 shows altered binding ability to BTB-adaptor proteins leading to diverse phenotypes of CUL3-related disorders.	KLHL8 KLHL18	5.03e-04	23	50	2	33130828
Pubmed	Hepatic Glucocorticoid Receptor Plays a Greater Role Than Adipose GR in Metabolic Syndrome Despite Renal Compensation.	PFKFB3 GPAT4	5.48e-04	24	50	2	27754788
Pubmed	The LIFEdb database in 2006.	ABRA AKT3 MAT2B SMC6 KLHL8 KLHL18	5.65e-04	720	50	6	16381901
Pubmed	From ORFeome to biology: a functional genomics pipeline.	ABRA AKT3 MAT2B SMC6 KLHL8 KLHL18	5.73e-04	722	50	6	15489336
Pubmed	Cell cycle-dependent phosphorylation regulates RECQL4 pathway choice and ubiquitination in DNA double-strand break repair.	SF3B3 RNMT MAT2B CCT4 POTEKP HECTD1 PCCB NDUFS2	5.90e-04	1335	50	8	29229926
Pubmed	Insights into the ubiquitin-proteasome system of human embryonic stem cells.	SF3B3 SRPK2 CCT4 HECTD1	6.09e-04	269	50	4	29511261
Pubmed	System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes.	WWP1 HECTD1	6.44e-04	26	50	2	26949039
Pubmed	WWP2 is an E3 ubiquitin ligase for PTEN.	WWP1 PCCB	8.02e-04	29	50	2	21532586
Pubmed	DNA cloning using in vitro site-specific recombination.	ABRA AKT3 MAT2B SMC6 KLHL8 KLHL18	9.39e-04	794	50	6	11076863
Pubmed	APC haploinsufficiency coupled with p53 loss sufficiently induces mucinous cystic neoplasms and invasive pancreatic carcinoma in mice.	AKT3 EGFR	1.10e-03	34	50	2	26411367
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	MIA3 TRIO GLS ADGRB2 CCT4 PCCB NDUFS2	1.16e-03	1139	50	7	36417873
Pubmed	Fine mapping and association studies of a high-density lipoprotein cholesterol linkage region on chromosome 16 in French-Canadian subjects.	LDHD CHST5	1.17e-03	35	50	2	19844255
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	MIA3 SF3B3 EGFR MAT2B GLS SRPK2 GPAT4 NDUFS2	1.19e-03	1487	50	8	33957083
Pubmed	Quantitative Proteomics Reveals Dynamic Interactions of the Minichromosome Maintenance Complex (MCM) in the Cellular Response to Etoposide Induced DNA Damage.	SF3B3 RNMT MAT2B GLS CCT4 HAS1	1.28e-03	844	50	6	25963833
Pubmed	Two-Dimensional Fractionation Method for Proteome-Wide Cross-Linking Mass Spectrometry Analysis.	MIA3 SF3B3 HKDC1 SRPK2 CCT4 NDUFS2	1.31e-03	847	50	6	35235311
GeneFamily	Kelch like\|BTB domain containing	KLHL8 KLHL18 KLHL31	9.29e-05	42	38	3	617
GeneFamily	Ankyrin repeat domain containing\|POTE ankyrin domain containing	POTEKP POTEI	3.31e-04	13	38	2	685
GeneFamily	Basic leucine zipper proteins\|BTB domain containing	KLHL8 KLHL18 KLHL31	2.78e-03	134	38	3	861
GeneFamily	Ankyrin repeat domain containing	GLS POTEI HECTD1	1.42e-02	242	38	3	403
Disease	Glioblastoma Multiforme	AKT3 EGFR SRPK2 STKLD1 POLK	1.04e-06	111	48	5	C1621958
Disease	fatty acid measurement	MYO1H PCIF1 PCSK7 KLHL8 POLK PCCB	7.30e-05	436	48	6	EFO_0005110
Disease	Cardiomyopathy, Familial Idiopathic	ABRA EGFR PCCB	7.50e-05	50	48	3	C1449563
Disease	triglycerides to total lipids in large LDL percentage	PCIF1 POLK PCCB	7.96e-05	51	48	3	EFO_0022331
Disease	triglyceride measurement, high density lipoprotein cholesterol measurement	MYO1H PCIF1 PCSK7 KLHL8 PCCB	8.22e-05	274	48	5	EFO_0004530, EFO_0004612
Disease	low density lipoprotein cholesterol measurement, phospholipids:total lipids ratio	PCIF1 PCSK7 KLHL8 PCCB	1.13e-04	153	48	4	EFO_0004611, EFO_0020946
Disease	cholesterol to total lipids in IDL percentage	PCSK7 POLK PCCB	1.30e-04	60	48	3	EFO_0022233
Disease	triglyceride measurement, low density lipoprotein cholesterol measurement	MYO1H PCIF1 PCSK7 PCCB	1.55e-04	166	48	4	EFO_0004530, EFO_0004611
Disease	phospholipids:total lipids ratio, intermediate density lipoprotein measurement	PCIF1 PCSK7 PCCB	1.80e-04	67	48	3	EFO_0008595, EFO_0020946
Disease	triglycerides to phosphoglycerides ratio	PCIF1 PCSK7 PCCB	1.88e-04	68	48	3	EFO_0022327
Disease	free cholesterol to total lipids in large LDL percentage	PCIF1 POLK PCCB	2.41e-04	74	48	3	EFO_0022280
Disease	low density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio	MYO1H PCIF1 PCSK7 PCCB	3.16e-04	200	48	4	EFO_0004611, EFO_0020945
Disease	autosomal dominant intellectual developmental disorder (is_implicated_in)	KMT2B TRIO	3.47e-04	17	48	2	DOID:0060307 (is_implicated_in)
Disease	very low density lipoprotein cholesterol measurement, cholesterol:total lipids ratio	PCIF1 PCSK7 KLHL8 PCCB	4.68e-04	222	48	4	EFO_0008317, EFO_0020943
Disease	glioma	AKT3 EGFR	5.86e-04	22	48	2	EFO_0005543
Disease	chylomicron measurement, very low density lipoprotein cholesterol measurement	MYO1H PCSK7 PCCB	6.93e-04	106	48	3	EFO_0008317, EFO_0008596
Disease	chylomicron measurement, very low density lipoprotein cholesterol measurement, phospholipid measurement	PCIF1 PCSK7 PCCB	7.51e-04	109	48	3	EFO_0004639, EFO_0008317, EFO_0008596
Disease	cholesteryl ester measurement, chylomicron measurement, very low density lipoprotein cholesterol measurement	PCIF1 PCSK7 PCCB	7.72e-04	110	48	3	EFO_0008317, EFO_0008596, EFO_0010351
Disease	free cholesterol measurement, chylomicron measurement, very low density lipoprotein cholesterol measurement	MYO1H PCSK7 PCCB	7.72e-04	110	48	3	EFO_0008317, EFO_0008591, EFO_0008596
Disease	chylomicron measurement, total cholesterol measurement, very low density lipoprotein cholesterol measurement	PCIF1 PCSK7 PCCB	7.72e-04	110	48	3	EFO_0004574, EFO_0008317, EFO_0008596
Disease	triglyceride measurement, intermediate density lipoprotein measurement	PCIF1 PCSK7 PCCB	7.92e-04	111	48	3	EFO_0004530, EFO_0008595
Disease	very low density lipoprotein cholesterol measurement	PCIF1 PCSK7 KLHL8 PCCB	8.45e-04	260	48	4	EFO_0008317
Disease	very low density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio	PCIF1 PCSK7 KLHL8 PCCB	8.95e-04	264	48	4	EFO_0008317, EFO_0020944
Disease	sleep duration, high density lipoprotein cholesterol measurement	MYO1H PCIF1 PCSK7	1.02e-03	121	48	3	EFO_0004612, EFO_0005271
Disease	central nervous system cancer, glioma	AKT3 EGFR	1.02e-03	29	48	2	EFO_0000326, EFO_0005543
Disease	cholesterol:total lipids ratio, high density lipoprotein cholesterol measurement	MYO1H PCIF1 PCSK7 PCCB	1.05e-03	276	48	4	EFO_0004612, EFO_0020943
Disease	triglycerides:total lipids ratio, intermediate density lipoprotein measurement	PCIF1 PCSK7 PCCB	1.17e-03	127	48	3	EFO_0008595, EFO_0020947
Disease	Squamous cell carcinoma of lung	EGFR WNK3	1.25e-03	32	48	2	C0149782
Disease	phospholipids:total lipids ratio, high density lipoprotein cholesterol measurement	MYO1H PCIF1 PCSK7 KLHL8	1.56e-03	307	48	4	EFO_0004612, EFO_0020946
Disease	total cholesterol measurement, high density lipoprotein cholesterol measurement	MYO1H PCIF1 PCSK7 PCCB	1.71e-03	315	48	4	EFO_0004574, EFO_0004612
Disease	triglyceride measurement, phospholipid measurement	PCIF1 PCSK7 PCCB	1.74e-03	146	48	3	EFO_0004530, EFO_0004639
Disease	phospholipid measurement, high density lipoprotein cholesterol measurement	MYO1H PCIF1 PCSK7 KLHL8	1.83e-03	321	48	4	EFO_0004612, EFO_0004639
Disease	triglycerides:total lipids ratio, low density lipoprotein cholesterol measurement	PCIF1 PCSK7 PCCB	1.88e-03	150	48	3	EFO_0004611, EFO_0020947
Disease	low density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio	PCIF1 PCSK7 KLHL8	1.99e-03	153	48	3	EFO_0004611, EFO_0020944
Disease	cortical thickness	AKT3 KMT2B EGFR GLS KLHL8 PCCB KLHL18	2.03e-03	1113	48	7	EFO_0004840
Disease	Agents acting on the renin-angiotensin system use measurement	MIA3 SF3B3 PCCB SVEP1	2.14e-03	335	48	4	EFO_0009931
Disease	vitamin D measurement	NPHS2 MIA3 PCSK7 KLHL8	2.17e-03	336	48	4	EFO_0004631
Disease	triglycerides in large LDL measurement	PCIF1 PCCB	2.24e-03	43	48	2	EFO_0022319
Disease	free cholesterol in very small VLDL measurement	PCIF1 PCCB	2.67e-03	47	48	2	EFO_0022275
Disease	high density lipoprotein particle size measurement	MYO1H PCIF1 PCSK7	2.69e-03	170	48	3	EFO_0008592
Disease	serum alanine aminotransferase measurement	NTNG2 RNMT APOL5 HKDC1 KLHL8 PCCB	2.74e-03	869	48	6	EFO_0004735
Disease	schizophrenia, anorexia nervosa	AKT3 SRPK2	2.79e-03	48	48	2	MONDO_0005090, MONDO_0005351
Disease	Cardiomyopathy, Dilated	ABRA EGFR	2.79e-03	48	48	2	C0007193
Disease	coronary artery disease	MIA3 SF3B3 GLS TMOD4 PTPRU PCCB SVEP1	3.01e-03	1194	48	7	EFO_0001645
Disease	triglycerides to total lipids in medium LDL percentage	POLK PCCB	3.02e-03	50	48	2	EFO_0022334
Disease	cholesteryl esters to total lipids in IDL percentage	PCSK7 PCCB	3.02e-03	50	48	2	EFO_0022247
Disease	free cholesterol to total lipids in small HDL percentage	PCIF1 POLK	3.14e-03	51	48	2	EFO_0022285

Protein segments in the cluster

Peptide	Gene	Start	Entry
RCPAFHEMCRDEYVM	ADGRB2	526	O60241
RAFYYAMCAETDAML	ARSK	276	Q6UWY0
LCYVALDSEQEMAMA	POTEKP	216	Q9BYX7
EAAYMVDMARERFEA	ADCK5	451	Q3MIX3
MACDLDMVALLEHYD	CCDC157	46	Q569K6
KYDEDGMDCMDNERR	AKT3	451	Q9Y243
RFALSAMDMEQRDYD	GLS	571	O94925
ECYMLAAMACDRYVA	OR8D4	111	Q8NGM9
ECFLLSMMAYDRFVA	OR10A7	111	Q8NGE5
DFLIREMSVENCMYV	KLHL31	161	Q9H511
MTKYEMACAIADAFN	MAT2B	256	Q9NZL9
EEGRMPFYAEECASM	PCSK7	356	Q16549
RIDLMDMADQYACDH	KLHL8	181	Q9P2G9
AEAMDDFMKRISCYE	PFKFB3	181	Q16875
IMEIDAICYYRMENA	NPHS2	186	Q9NP85
IGCYMFRMDDFDVVD	KMT2B	2626	Q9UMN6
FDRLDYVSMMCNEQA	NDUFS2	136	O75306
MLDMAECEGVVDIYN	PTPRU	1101	Q92729
ESDMFVEHRCADFGM	PCCB	81	P05166
NFYRALMDEEDMDDV	EGFR	996	P00533
NAEEYVDLMFDFCMH	HECTD1	2441	Q9ULT8
MAFDGCYHDSEIDMD	GABRR3	381	A8MPY1
FAETMMCAVLYDAAN	KLHL18	146	O94889
FCEELMDAMVSHFER	PCIF1	556	Q9H4Z3
FYFCRKGMETIMDDE	GPAT4	116	Q86UL3
FLDEVMMDACNRYSK	LDHD	301	Q86WU2
DLYMVDMFREVFADE	HAS1	141	Q92839
FESYEQADMMLRNAC	RNMT	291	O43148
ECVLLAVMAYDRYMA	OR6A2	116	O95222
FYAEDCMEAFGMSAR	NTNG2	166	Q96CW9
DECSMLMYRGEALED	MIA3	41	Q5JRA6
ACYMEDMSNIDLVEG	HKDC1	236	Q2TB90
MESYCVRAFADAMEV	CCT4	446	P50991
LCYVALDFEQEMAMA	POTEI	916	P0CG38
EMFYKAARCDDTDLM	SVEP1	801	Q4LDE5
RAEEHIYREMMDMCF	ABRA	301	Q8N0Z2
YFLFEELMRCDKDSM	APOL5	76	Q9BWW9
DLMRSIFLCDMDVFD	CHST5	116	Q9GZS9
CMDDHYASQALEELM	STKLD1	61	Q8NE28
LMCVDDAYVRRMAAE	SRPK2	221	P78362
IDMDAFYAAVEMRDN	POLK	106	Q9UBT6
DMDDCSQLMAFVRYI	ZBED8	181	Q8IZ13
FRCLDEFDVYMDMVN	SMC6	1011	Q96SB8
VLERDFAEMCADYMA	RNF121	191	Q9H920
MFACLEMDYEEADND	SF3B3	181	Q15393
AEMCDIAAILDMYTL	TMOD4	126	Q9NZQ9
CAKDVVMRMFDEQYS	ZBED5	221	Q49AG3
EECGLEMYFSVDMEI	WWP1	716	Q9H0M0
QANHYDMDMIRDCAE	TRIO	976	O75962
DESVDVYAFGMCMLE	WNK3	326	Q9BYP7
VYAIADNAYRMMCAE	MYO1H	81	Q8N1T3