Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcessbiphenyl catabolic process

UGT2B4 UGT2B7 UGT2B28 UGT2B11

3.34e-0781744GO:0070980
GeneOntologyBiologicalProcessbiphenyl metabolic process

UGT2B4 UGT2B7 UGT2B28 UGT2B11

9.88e-07101744GO:0018879
GeneOntologyBiologicalProcessxenobiotic glucuronidation

UGT2B4 UGT2B7 UGT2B28 UGT2B11

2.30e-06121744GO:0052697
GeneOntologyBiologicalProcesscellular glucuronidation

UGT2B4 UGT2B7 UGT2B28 UGT2B11

2.62e-05211744GO:0052695
GeneOntologyBiologicalProcessglucuronate metabolic process

UGT2B4 UGT2B7 UGT2B28 UGT2B11

6.33e-05261744GO:0019585
GeneOntologyBiologicalProcessuronic acid metabolic process

UGT2B4 UGT2B7 UGT2B28 UGT2B11

6.33e-05261744GO:0006063
Domainfn3

CHL1 IL12RB2 MYLK AXL LRFN3 OBSCN OBSL1 PTPRU PTPRC USH2A IL27RA EPHA7

5.36e-0816217912PF00041
DomainFN3

CHL1 IL12RB2 MYLK AXL LRFN3 OBSCN OBSL1 PTPRU PTPRC USH2A IL27RA EPHA7

2.30e-0718517912SM00060
DomainFN3

CHL1 IL12RB2 MYLK AXL LRFN3 OBSCN OBSL1 PTPRU PTPRC USH2A IL27RA EPHA7

5.04e-0719917912PS50853
DomainFN3_dom

CHL1 IL12RB2 MYLK AXL LRFN3 OBSCN OBSL1 PTPRU PTPRC USH2A IL27RA EPHA7

8.49e-0720917912IPR003961
DomainIg-like_fold

CHL1 IL12RB2 ISLR2 MYLK HLA-C SIGLEC9 AXL LRFN3 HLA-E OBSCN OBSL1 PAPLN PTPRU IGSF10 PTPRC HMCN2 PXDNL USH2A IL27RA EPHA7

1.50e-0570617920IPR013783
DomainIg_I-set

CHL1 MYLK AXL LRFN3 OBSCN OBSL1 PAPLN IGSF10 HMCN2 PXDNL

1.53e-0519017910IPR013098
DomainI-set

CHL1 MYLK AXL LRFN3 OBSCN OBSL1 PAPLN IGSF10 HMCN2 PXDNL

1.53e-0519017910PF07679
Domain-

CHL1 IL12RB2 ISLR2 MYLK HLA-C SIGLEC9 AXL LRFN3 HLA-E OBSCN OBSL1 PAPLN PTPRU IGSF10 PTPRC PXDNL USH2A IL27RA EPHA7

2.12e-05663179192.60.40.10
DomainUDPGT

UGT2B4 UGT2B7 UGT2B28 UGT2B11

4.30e-05211794PF00201
DomainUDPGT

UGT2B4 UGT2B7 UGT2B28 UGT2B11

4.30e-05211794PS00375
DomainUDP_glucos_trans

UGT2B4 UGT2B7 UGT2B28 UGT2B11

4.30e-05211794IPR002213
DomainIG_LIKE

CHL1 ISLR2 MYLK HLA-C SIGLEC9 AXL LRFN3 HLA-E OBSCN OBSL1 PAPLN PTPRU IGSF10 HMCN2 PXDNL

8.03e-0549117915PS50835
DomainARHGEF5_35

ARHGEF5 ARHGEF35

9.13e-0521792PF15441
DomainARHGEF5/35_N

ARHGEF5 ARHGEF35

9.13e-0521792IPR029212
DomainIg-like_dom

CHL1 ISLR2 MYLK HLA-C SIGLEC9 AXL LRFN3 HLA-E OBSCN OBSL1 PAPLN PTPRU IGSF10 HMCN2 PXDNL

1.05e-0450317915IPR007110
DomainDUF4599

SPATA31A3 SPATA31A7 SPATA31A5

1.79e-04121793PF15371
DomainDUF4599

SPATA31A3 SPATA31A7 SPATA31A5

1.79e-04121793IPR027970
DomainIG

CHL1 ISLR2 MYLK SIGLEC9 AXL LRFN3 OBSCN OBSL1 PAPLN PTPRU IGSF10 HMCN2 PXDNL

2.18e-0442117913SM00409
DomainIg_sub

CHL1 ISLR2 MYLK SIGLEC9 AXL LRFN3 OBSCN OBSL1 PAPLN PTPRU IGSF10 HMCN2 PXDNL

2.18e-0442117913IPR003599
Domain-

MAN2B1 NAGA FUCA1

2.92e-041417932.60.40.1180
DomainDH_1

ARHGEF5 OBSCN PLEKHG4B NGEF VAV1

3.43e-04631795PS00741
DomainGlyco_hydro_b

MAN2B1 NAGA FUCA1

3.62e-04151793IPR013780
DomainIGc2

CHL1 MYLK LRFN3 OBSCN OBSL1 PAPLN IGSF10 HMCN2 PXDNL

4.52e-042351799SM00408
DomainIg_sub2

CHL1 MYLK LRFN3 OBSCN OBSL1 PAPLN IGSF10 HMCN2 PXDNL

4.52e-042351799IPR003598
DomainRhoGEF

ARHGEF5 OBSCN PLEKHG4B NGEF VAV1

4.89e-04681795SM00325
DomainGDS_CDC24_CS

ARHGEF5 OBSCN NGEF VAV1

5.16e-04391794IPR001331
DomainNAP_family

TSPY26P TSPYL5 TSPYL4

5.33e-04171793IPR002164
DomainNAP

TSPY26P TSPYL5 TSPYL4

5.33e-04171793PF00956
DomainRhoGEF

ARHGEF5 OBSCN PLEKHG4B NGEF VAV1

5.59e-04701795PF00621
DomainDH_2

ARHGEF5 OBSCN PLEKHG4B NGEF VAV1

5.59e-04701795PS50010
Domain-

ARHGEF5 OBSCN PLEKHG4B NGEF VAV1

5.97e-047117951.20.900.10
DomainDH-domain

ARHGEF5 OBSCN PLEKHG4B NGEF VAV1

5.97e-04711795IPR000219
DomainNa/HCO3_transpt

SLC4A10 SLC4A5

8.96e-0451792IPR003024
DomainADAM_spacer1

PAPLN ADAMTS9 ADAMTS14

1.33e-03231793IPR010294
DomainADAM_spacer1

PAPLN ADAMTS9 ADAMTS14

1.33e-03231793PF05986
DomainMHC_I_a_C

HLA-C HLA-E

1.34e-0361792IPR010579
DomainMHC_I_C

HLA-C HLA-E

1.34e-0361792PF06623
DomainPH

CDC42BPG ARHGEF5 ARHGAP26 OBSCN PLEKHG4B NGEF PLCD1 VAV1 PSD4

1.48e-032781799SM00233
DomainPeptidase_M12B_ADAM-TS

PAPLN ADAMTS9 ADAMTS14

1.51e-03241793IPR013273
DomainPH_DOMAIN

CDC42BPG ARHGEF5 ARHGAP26 OBSCN PLEKHG4B NGEF PLCD1 VAV1 PSD4

1.52e-032791799PS50003
DomainPH_domain

CDC42BPG ARHGEF5 ARHGAP26 OBSCN PLEKHG4B NGEF PLCD1 VAV1 PSD4

1.56e-032801799IPR001849
DomainGlycoside_hydrolase_SF

GLB1L NAGA GANAB FUCA1

1.66e-03531794IPR017853
DomainPH

CDC42BPG ARHGEF5 ARHGAP26 OBSCN NGEF PLCD1 VAV1 PSD4

1.68e-032291798PF00169
DomainANION_EXCHANGER_2

SLC4A10 SLC4A5

1.86e-0371792PS00220
DomainANION_EXCHANGER_1

SLC4A10 SLC4A5

1.86e-0371792PS00219
PathwayREACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK

ARHGEF5 BAD OBSCN ARHGEF35 NGEF VAV1

1.58e-05591296M11215
PathwayREACTOME_ASPIRIN_ADME

SLC22A7 UGT2B4 UGT2B7 UGT2B28 UGT2B11

4.84e-05441295M45014
PathwayREACTOME_PREDNISONE_ADME

UGT2B4 UGT2B7 UGT2B28 UGT2B11

5.18e-05231294MM16639
PathwayREACTOME_ASPIRIN_ADME

SLC22A7 UGT2B4 UGT2B7 UGT2B28 UGT2B11

5.41e-05451295MM15694
PathwayREACTOME_GLUCURONIDATION

UGT2B4 UGT2B7 UGT2B28 UGT2B11

6.17e-05241294MM14599
PathwayREACTOME_CELL_DEATH_SIGNALLING_VIA_NRAGE_NRIF_AND_NADE

ARHGEF5 BAD OBSCN ARHGEF35 NGEF VAV1

6.76e-05761296M19832
PathwayREACTOME_GLUCURONIDATION

UGT2B4 UGT2B7 UGT2B28 UGT2B11

7.29e-05251294M17787
PathwayWP_GLUCURONIDATION

UGT2B4 UGT2B7 UGT2B28 UGT2B11

7.29e-05251294MM15820
PathwayKEGG_ASCORBATE_AND_ALDARATE_METABOLISM

UGT2B4 UGT2B7 UGT2B28 UGT2B11

7.29e-05251294M605
PathwayWP_GLUCURONIDATION

UGT2B4 UGT2B7 UGT2B28 UGT2B11

8.56e-05261294M39404
PathwayREACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK

ARHGEF5 BAD OBSCN NGEF VAV1

1.09e-04521295MM14743
PathwayKEGG_PENTOSE_AND_GLUCURONATE_INTERCONVERSIONS

UGT2B4 UGT2B7 UGT2B28 UGT2B11

1.16e-04281294M19580
PathwayREACTOME_HEPARAN_SULFATE_HEPARIN_HS_GAG_METABOLISM

B4GALT7 GLB1L NDST2 B3GALT6 AGRN

1.31e-04541295MM14633
PathwayKEGG_STEROID_HORMONE_BIOSYNTHESIS

CYP21A2 UGT2B4 UGT2B7 UGT2B28 UGT2B11

1.43e-04551295M14933
PathwayREACTOME_HEPARAN_SULFATE_HEPARIN_HS_GAG_METABOLISM

B4GALT7 GLB1L NDST2 B3GALT6 AGRN

1.70e-04571295M692
PathwayREACTOME_P75_NTR_RECEPTOR_MEDIATED_SIGNALLING

ARHGEF5 BAD OBSCN ARHGEF35 NGEF VAV1

2.61e-04971296M9400
PathwayREACTOME_PARACETAMOL_ADME

UGT2B4 UGT2B7 UGT2B28 UGT2B11

4.30e-04391294MM15695
PathwayREACTOME_CELL_DEATH_SIGNALLING_VIA_NRAGE_NRIF_AND_NADE

ARHGEF5 BAD OBSCN NGEF VAV1

4.46e-04701295MM14824
PathwayREACTOME_DRUG_ADME

SLC22A7 UGT2B4 UGT2B7 UGT2B28 UGT2B11 VAV1

4.90e-041091296M45012
PathwayKEGG_PORPHYRIN_AND_CHLOROPHYLL_METABOLISM

UGT2B4 UGT2B7 UGT2B28 UGT2B11

5.21e-04411294M7399
PathwayREACTOME_DRUG_ADME

SLC22A7 UGT2B4 UGT2B7 UGT2B28 UGT2B11 VAV1

7.80e-041191296MM15692
PathwayPID_RHOA_REG_PATHWAY

ARHGEF5 OBSCN NGEF VAV1

8.11e-04461294M68
PathwaySIG_BCR_SIGNALING_PATHWAY

BAD PPP1R13B PTPRC VAV1

8.11e-04461294M8626
PathwayKEGG_MEDICUS_REFERENCE_GLYCOSAMINOGLYCAN_BIOSYNTHESIS_LINKAGE_TETRASACCHARIDE

B4GALT7 B3GALT6

8.16e-0451292M47914
PathwayREACTOME_G_ALPHA_12_13_SIGNALLING_EVENTS

ARHGEF5 OBSCN ARHGEF35 NGEF VAV1

8.25e-04801295M800
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

GTPBP4 IL12RB2 ISLR2 VWA8 OBSL1 MMP21 EMILIN3 WDR26 INO80D ABCA7 SIRT5 LARP4B IGF2BP2 SULF2 SF3B3 HMCN2 ATXN1 BAZ2A SEC16A ZNF324 RIC8A YME1L1 VAV1 AGTPBP1 AURKB

1.48e-0911161852531753913
Pubmed

Weak activity of UDP-glucuronosyltransferase toward Bisphenol analogs in mouse perinatal development.

UGT2B4 UGT2B7 UGT2B28 UGT2B11

2.68e-087185426074487
Pubmed

Hetero-oligomer formation of mouse UDP-glucuronosyltransferase (UGT) 2b1 and 1a1 results in the gain of glucuronidation activity towards morphine, an activity which is absent in homo-oligomers of either UGT.

UGT2B4 UGT2B7 UGT2B28 UGT2B11

5.34e-088185432093886
Pubmed

Mapping of the Sca1 and pcd genes on mouse chromosome 13 provides evidence that they are different genes.

FANCC ATXN1 AGTPBP1

1.48e-07318538575786
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

SEMA6B ATG10 MAN2B1 VWA8 KMT5C ARHGAP26 OBSCN PAPLN ABCA7 TBC1D17 LIME1 NCOR1 AHNAK SEC16A ANKRD11 MAP3K11 RIC8A ZNF324B HERC1 AGRN PCNT

5.11e-0711051852135748872
Pubmed

Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion.

CHL1 ISLR2 AXL LRFN3 OBSCN OBSL1 PTPRU IGSF10

2.71e-06162185825826454
Pubmed

The testis-specific VAD1.3/AEP1 interacts with β-actin and syntaxin 1 and directs peri-nuclear/Golgi expression with bipartite nucleus localization (BNL) sequence.

SPATA31A3 SPATA31A7 SPATA31A5

2.93e-066185320850414
Pubmed

Targeted disruption of the spermatid-specific gene Spata31 causes male infertility.

SPATA31A3 SPATA31A7 SPATA31A5

2.93e-066185325930072
Pubmed

Recombination in the class III region of the mouse major histocompatibility complex.

HLA-C CYP21A2 HLA-E CFB

5.26e-062218547916002
Pubmed

Epitope-Specific Vaccination Limits Clonal Expansion of Heterologous Naive T Cells during Viral Challenge.

HLA-C HLA-E PTPRC

8.13e-068185327732841
Pubmed

Proteomic analysis and identification of cellular interactors of the giant ubiquitin ligase HERC2.

ARHGEF5 HLA-E OBSL1 RIC8A HERC1 AURKB EPHA7

1.02e-05139185725476789
Pubmed

Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.

PLIN4 SEMA6B MAN2B1 PITRM1 HLA-C VWA8 AXL HLA-E AXIN1 IGF2BP2 UBA7 CS GANAB SF3B3 PTPRC GBP5 AHNAK SEC16A ADAMTS14 TMEM231 AGRN RCN3

1.04e-0514511852230550785
Pubmed

Transgenic major histocompatibility complex class I antigen expressed in mouse trophoblast affects maternal immature B cells.

HLA-C HLA-E PTPRC

1.21e-059185311466198
Pubmed

Meiotic recombination at the Lmp2 hotspot tolerates minor sequence divergence between homologous chromosomes.

HLA-C CYP21A2 HLA-E

2.37e-051118538537128
Pubmed

METTL3 promotes ovarian carcinoma growth and invasion through the regulation of AXL translation and epithelial to mesenchymal transition.

METTL3 AXL

2.81e-052185230249526
Pubmed

The m6A methyltransferase METTL3 promotes trophoblast cell invasion by regulating MYLK expression.

METTL3 MYLK

2.81e-052185236170767
Pubmed

Expression of UDP-glucuronosyltransferases (UGTs) 2B7 and 1A6 in the human brain and identification of 5-hydroxytryptamine as a substrate.

UGT2B4 UGT2B7

2.81e-052185210222050
Pubmed

A Conserved HIV-1-Derived Peptide Presented by HLA-E Renders Infected T-cells Highly Susceptible to Attack by NKG2A/CD94-Bearing Natural Killer Cells.

HLA-C HLA-E

2.81e-052185226828202
Pubmed

A quantitative study of the Golgi retention of glycosyltransferases.

B4GALT7 B3GALT6

2.81e-052185234533190
Pubmed

HLA-E is expressed on trophoblast and interacts with CD94/NKG2 receptors on decidual NK cells.

HLA-C HLA-E

2.81e-052185210898498
Pubmed

Cerebellar mutations affecting the postnatal survival of Purkinje cells in the mouse disclose a longitudinal pattern of differentially sensitive cells.

HERC1 AGTPBP1

2.81e-05218523678603
Pubmed

Substrate specificity of the human UDP-glucuronosyltransferase UGT2B4 and UGT2B7. Identification of a critical aromatic amino acid residue at position 33.

UGT2B4 UGT2B7

2.81e-052185217263731
Pubmed

Single nucleotide polymorphisms and haplotype frequencies of UGT2B4 and UGT2B7 in a Japanese population.

UGT2B4 UGT2B7

2.81e-052185215319348
Pubmed

Specific isoforms of the resident endoplasmic reticulum protein glucosidase II associate with the CD45 protein-tyrosine phosphatase via a lectin-like interaction.

GANAB PTPRC

2.81e-052185210921916
Pubmed

Immune modulation of vascular resident cells by Axl orchestrates carotid intima-media thickening.

AXL PTPRC

2.81e-052185222538191
Pubmed

WDR26 is a new partner of Axin1 in the canonical Wnt signaling pathway.

WDR26 AXIN1

2.81e-052185227098453
Pubmed

HLA-C and HLA-E reduce antibody-dependent natural killer cell-mediated cytotoxicity of HIV-infected primary T cell blasts.

HLA-C HLA-E

2.81e-052185215316337
Pubmed

Selective downregulation of HLA-C and HLA-E in childhood acute lymphoblastic leukaemia.

HLA-C HLA-E

2.81e-052185226527563
Pubmed

Quantitative analysis of UGT2B28 mRNA expression by real-time RT-PCR and application to human tissue distribution study.

UGT2B28 UGT2B11

2.81e-052185221679149
Pubmed

Severe Peripheral Joint Laxity is a Distinctive Clinical Feature of Spondylodysplastic-Ehlers-Danlos Syndrome (EDS)-B4GALT7 and Spondylodysplastic-EDS-B3GALT6.

B4GALT7 B3GALT6

2.81e-052185231614862
Pubmed

Significance of association of HLA-C and HLA-E with psoriatic arthritis.

HLA-C HLA-E

2.81e-052185225454626
Pubmed

Association between sex hormones regulation-related SNP rs12233719 and lung cancer risk among never-smoking Chinese women.

SHBG UGT2B7

2.81e-052185233595913
Pubmed

Dual inhibition of TGFβ and AXL as a novel therapy for human colorectal adenocarcinoma with mesenchymal phenotype.

AXL TGFBR2

2.81e-052185233570712
Pubmed

LIME mediates immunological synapse formation through activation of VAV.

LIME1 VAV1

2.81e-052185222395814
Pubmed

Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.

LRCH2 HLA-C ARHGEF5 ARHGAP26 SIRT5 PLEKHG4B CS GANAB CSE1L AHNAK SEC16A NGEF YME1L1 TOR1AIP1 VAV1 AURKB

3.46e-059161851632203420
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

HLA-C MTMR1 PPP1R13B PTPRU NCOR1 IGF2BP2 GANAB CSE1L PTPRC AHNAK SEC16A HERC1 ZKSCAN4 YME1L1 AGTPBP1 PCNT AURKB

4.97e-0510491851727880917
Pubmed

No dosage effect of recombinational hotspots in the mouse major histocompatibility complex.

HLA-C CYP21A2 HLA-E

5.16e-051418537910587
Pubmed

Missing self-recognition of Ocil/Clr-b by inhibitory NKR-P1 natural killer cell receptors.

HLA-C HLA-E PTPRC

6.43e-0515185314990792
Pubmed

New molecular markers for the distal end of the t-complex and their relationships to mutations affecting mouse development.

HLA-C HLA-E AXIN1

6.43e-051518531350556
Pubmed

Mouse lymphotoxin and tumor necrosis factor: structural analysis of the cloned genes, physical linkage, and chromosomal position.

HLA-C CYP21A2 HLA-E

6.43e-051518532885372
Pubmed

NRAGE, a p75 neurotrophin receptor-interacting protein, induces caspase activation and cell death through a JNK-dependent mitochondrial pathway.

BAD OBSCN NGEF VAV1

8.13e-0543185412376548
Pubmed

Human transcription factor protein interaction networks.

GTPBP4 FLI1 PITRM1 PEG10 PPP1R13B INO80D ZEB2 NCOR1 LARP4B IGF2BP2 GANAB HOXC9 CSE1L MID1IP1 ATXN1 SEC16A HERC1 ZKSCAN4 SLX4 ZNF121

8.17e-0514291852035140242
Pubmed

METTL3/IGF2BP2 axis affects the progression of colorectal cancer by regulating m6A modification of STAG3.

METTL3 IGF2BP2

8.41e-053185237828232
Pubmed

Chromosomal localization of Ewing sarcoma EWSR1/FLI1 protein promotes the induction of aneuploidy.

FLI1 AURKB

8.41e-053185233293370
Pubmed

Identification of the CD45-associated 116-kDa and 80-kDa proteins as the alpha- and beta-subunits of alpha-glucosidase II.

GANAB PTPRC

8.41e-05318529148925
Pubmed

Differential regulation of activation-induced tyrosine phosphorylation and recruitment of SLP-76 to Vav by distinct isoforms of the CD45 protein-tyrosine phosphatase.

PTPRC VAV1

8.41e-05318528703037
Pubmed

cDNA cloning and expression of two new members of the human liver UDP-glucuronosyltransferase 2B subfamily.

UGT2B4 UGT2B11

8.41e-05318528333863
Pubmed

Clopidogrel Carboxylic Acid Glucuronidation is Mediated Mainly by UGT2B7, UGT2B4, and UGT2B17: Implications for Pharmacogenetics and Drug-Drug Interactions .

UGT2B4 UGT2B7

8.41e-053185229138287
Pubmed

EWS-FLI1 target genes recovered from Ewing's sarcoma chromatin.

FLI1 TGFBR2

8.41e-053185215735734
Pubmed

Structural insight into M-band assembly and mechanics from the titin-obscurin-like-1 complex.

OBSCN OBSL1

8.41e-053185220133654
Pubmed

Ewing sarcoma EWS protein regulates midzone formation by recruiting Aurora B kinase to the midzone.

FLI1 AURKB

8.41e-053185225483190
Pubmed

Target neuron controls the integrity of afferent axon phenotype: a study on the Purkinje cell-climbing fiber system in cerebellar mutant mice.

HERC1 AGTPBP1

8.41e-05318527891151
Pubmed

METTL3 Intensifies the Progress of Oral Squamous Cell Carcinoma via Modulating the m6A Amount of PRMT5 and PD-L1.

METTL3 PRMT5

8.41e-053185234476262
Pubmed

Binding of Myomesin to Obscurin-Like-1 at the Muscle M-Band Provides a Strategy for Isoform-Specific Mechanical Protection.

OBSCN OBSL1

8.41e-053185227989621
Pubmed

Developmentally regulated changes in glucosidase II association with, and carbohydrate content of, the protein tyrosine phosphatase CD45.

GANAB PTPRC

8.41e-053185211564800
Pubmed

ALKBH5 controls the meiosis-coupled mRNA clearance in oocytes by removing the N 6-methyladenosine methylation.

METTL3 IGF2BP2

8.41e-053185237848452
Pubmed

Isolation of a human YAC contig encompassing a cluster of UGT2 genes and its regional localization to chromosome 4q13.

UGT2B4 UGT2B7

8.41e-05318527835904
Pubmed

Quantified colocalization reveals heterotypic histocompatibility class I antigen associations on trophoblast cell membranes: relevance for human pregnancy.

HLA-C HLA-E

8.41e-053185224006284
Pubmed

METTL3-mediated TIM1 promotes macrophage M1 polarization and inflammation through IGF2BP2-dependent manner.

METTL3 IGF2BP2

8.41e-053185239267336
Pubmed

Murine obscurin and Obsl1 have functionally redundant roles in sarcolemmal integrity, sarcoplasmic reticulum organization, and muscle metabolism.

OBSCN OBSL1

8.41e-053185231098411
Pubmed

Single-cell protein expression profiling resolves circulating and resident memory T cell diversity across tissues and infection contexts.

ZNF683 TGFBR2

8.41e-053185237392736
Pubmed

Gasdermin C Is Upregulated by Inactivation of Transforming Growth Factor β Receptor Type II in the Presence of Mutated Apc, Promoting Colorectal Cancer Proliferation.

GSDMC TGFBR2

8.41e-053185227835699
Pubmed

METTL3-mediated m6A mRNA methylation regulates neutrophil activation through targeting TLR4 signaling.

METTL3 PTPRC

8.41e-053185236920907
Pubmed

METTL3 facilitates tumor progression via an m6A-IGF2BP2-dependent mechanism in colorectal carcinoma.

METTL3 IGF2BP2

8.41e-053185231230592
Pubmed

Methadone inhibits CYP2D6 and UGT2B7/2B4 in vivo: a study using codeine in methadone- and buprenorphine-maintained subjects.

UGT2B4 UGT2B7

8.41e-053185222092298
Pubmed

Possible causal relationships between cerebellar patterns of foliation and hindlimb coordination in laboratory mice: a quantitative trait locus analysis.

ATXN1 AGTPBP1

8.41e-053185211529272
Pubmed

Inhibition of Mettl3 ameliorates osteoblastic senescence by mitigating m6A modifications on Slc1a5 via Igf2bp2-dependent mechanisms.

METTL3 IGF2BP2

8.41e-053185238844111
Pubmed

Molecular basis of the head-to-tail assembly of giant muscle proteins obscurin-like 1 and titin.

OBSCN OBSL1

8.41e-053185220489725
Pubmed

Genetic disruption of both Fancc and Fancg in mice recapitulates the hematopoietic manifestations of Fanconi anemia.

FANCC PTPRC

8.41e-053185220606166
Pubmed

The "m6A writer" METTL3 and the "m6A reader" IGF2BP2 regulate cutaneous T-cell lymphomas progression via CDKN2A.

METTL3 IGF2BP2

8.41e-053185235446451
Pubmed

Localization of a mouse heat shock Hsp70 gene within the H-2 complex.

HLA-C CYP21A2 HLA-E

9.53e-051718531978715
Pubmed

Tracts of high or low sequence divergence in the mouse major histocompatibility complex.

HLA-C CYP21A2 HLA-E

1.14e-041818536098460
Pubmed

The GRHL3-regulated long non-coding RNA lnc-DC modulates keratinocytes differentiation by interacting with IGF2BP2 and up-regulating ZNF750.

IGF2BP2 GRHL3

1.68e-044185238383230
Pubmed

Contribution of polymorphisms in UDP-glucuronosyltransferase and CYP2D6 to the individual variation in disposition of carvedilol.

UGT2B4 UGT2B7

1.68e-044185216849011
Pubmed

Exome sequencing in seven families and gene-based association studies indicate genetic heterogeneity and suggest possible candidates for fibromuscular dysplasia.

MYLK OBSCN

1.68e-044185226147384
Pubmed

Definitive class I human leukocyte antigen expression in gestational placentation: HLA-F, HLA-E, HLA-C, and HLA-G in extravillous trophoblast invasion on placentation, pregnancy, and parturition.

HLA-C HLA-E

1.68e-044185228185362
Pubmed

METTL3 mediates m6A modification of lncRNA CRNDE to promote ATG10 expression and improve brain ischemia/reperfusion injury through YTHDC1.

METTL3 ATG10

1.68e-044185239407279
Pubmed

PEG10 viral aspartic protease domain is essential for the maintenance of fetal capillary structure in the mouse placenta.

PEG10 PTPRC

1.68e-044185234559199
Pubmed

Aurora B but not rho/MLCK signaling is required for localization of diphosphorylated myosin II regulatory light chain to the midzone in cytokinesis.

MYLK AURKB

1.68e-044185223951055
Pubmed

Pax7 is necessary and sufficient for the myogenic specification of CD45+:Sca1+ stem cells from injured muscle.

PTPRC ATXN1

1.68e-044185215138500
Pubmed

Generation of B lymphoma cell lines from knockout mice by transformation in vivo with an Emu-myc transgene.

PTPRC VAV1

1.68e-044185210556550
Pubmed

Relative expression levels of the HLA class-I proteins in normal and HIV-infected cells.

HLA-C HLA-E

1.68e-044185225754738
Pubmed

Boat, an AXH domain protein, suppresses the cytotoxicity of mutant ataxin-1.

NCOR1 ATXN1

1.68e-044185216121196
Pubmed

Adenovirus serotype 5 vaccine vectors trigger IL-27-dependent inhibitory CD4+ T cell responses that impair CD8+ T cell function.

IL12RB2 IL27RA

1.68e-044185228239679
Pubmed

CTL-associated antigen-4 ligation induces rapid T cell polarization that depends on phosphatidylinositol 3-kinase, Vav-1, Cdc42, and myosin light chain kinase.

MYLK VAV1

1.68e-044185217579061
Pubmed

Isolation, characterization, and mapping of the mouse Fgd3 gene, a new Faciogenital Dysplasia (FGD1; Aarskog Syndrome) gene homologue.

FANCC ATXN1

1.68e-044185210721717
Pubmed

IGF2BP2 promotes the progression of ovarian endometriosis by regulating m6A-modified MEIS2 and GATA6.

METTL3 IGF2BP2

1.68e-044185236113831
Pubmed

Orientation and molecular map position of the complement genes in the mouse MHC.

CYP21A2 CFB

1.68e-04418523034587
Pubmed

Skp2-Mediated Stabilization of MTH1 Promotes Survival of Melanoma Cells upon Oxidative Stress.

HSPBAP1 GANAB HERC1 YME1L1

1.72e-0452185428947420
Pubmed

Modulation of CD4 lateral interaction with lymphocyte surface molecules induced by HIV-1 gp120.

HLA-C HLA-E PTPRC

1.84e-042118537539755
Pubmed

HIV-1 Nef control of cell signalling molecules: multiple strategies to promote virus replication.

HLA-C HLA-E VAV1

1.84e-0421185312734410
Pubmed

CUL4B Promotes Breast Carcinogenesis by Coordinating with Transcriptional Repressor Complexes in Response to Hypoxia Signaling Pathway.

ZEB2 NCOR1 GANAB PRMT5

1.85e-0453185434026424
Pubmed

WDFY4 is required for cross-presentation in response to viral and tumor antigens.

HLA-C VWA8 HLA-E GANAB SF3B3 AHNAK

1.96e-04156185630409884
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

GTPBP4 TASOR2 DHX8 LARP4B IGF2BP2 GANAB CSE1L BAZ2A PRMT5 AHNAK SEC16A PCNT

2.13e-046531851222586326
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

B4GALT7 MAN2B1 HLA-C AXL NAGA HLA-E B3GALT6 ABCA7 IGSF10 SULF2 GANAB TXNDC15 PRMT5 TMEM231 AGRN TOR1AIP1 RCN3

2.50e-0412011851735696571
Pubmed

The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.

SEMA6B ISLR2 B4GALT7 SIGLEC9 GLB1L LRFN3 PAPLN SULF2 TXNDC15 GBP5 PRRT3 TMEM231 YME1L1 RCN3 IL27RA

2.72e-049851851512975309
Pubmed

Majority of cerebrospinal fluid-contacting neurons in the spinal cord of C57Bl/6N mice is present in ectopic position unlike in other studied experimental mice strains and mammalian species.

SPATA31A3 SPATA31A7 SPATA31A5

2.76e-0424185332212159
Pubmed

Linkage map of mouse chromosome 17: localization of 27 new DNA markers.

HLA-C CYP21A2 HLA-E

2.76e-042418532574145
Pubmed

HLA-E-bound peptides influence recognition by inhibitory and triggering CD94/NKG2 receptors: preferential response to an HLA-G-derived nonamer.

HLA-C HLA-E

2.78e-04518529754572
Pubmed

The tyrosine phosphatase PTP1C associates with Vav, Grb2, and mSos1 in hematopoietic cells.

PTPRC VAV1

2.78e-04518528632004
GeneFamilyFibronectin type III domain containing

CHL1 IL12RB2 MYLK AXL LRFN3 OBSCN PTPRU PTPRC USH2A IL27RA EPHA7

1.56e-0816012611555
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

CHL1 MYLK LRFN3 OBSCN OBSL1 PAPLN IGSF10 HMCN2 PXDNL

1.90e-061611269593
GeneFamilyUDP glucuronosyltransferases

UGT2B4 UGT2B7 UGT2B28 UGT2B11

6.95e-05321264363
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

ARHGEF5 OBSCN ARHGEF35 NGEF VAV1

9.65e-05661265722
CoexpressionPILON_KLF1_TARGETS_UP

MYLK PITRM1 HLA-C HLA-E OBSL1 ZNF195 CFB LARP4B UGT2B4 UGT2B7 ETNK1 UGT2B28 DDHD2 FOXH1 UGT2B11 AGRN

1.51e-0654118416MM1061
CoexpressionGAUSSMANN_MLL_AF4_FUSION_TARGETS_G_UP

FLI1 PEG10 KDM5D CS UGT2B4 UGT2B7 UGT2B28 CTNND2 GRHL3 UGT2B11 EPHA7

3.19e-0626718411MM984
CoexpressionNABA_ECM_GLYCOPROTEINS

EMILIN3 PAPLN SSPOP IGSF10 HMCN2 PXDNL ZP4 USH2A AGRN

1.08e-051961849M3008
CoexpressionSHI_SPARC_TARGETS_UP

ARHGEF5 TGFBR2 AHRR ANKRD11

2.24e-05241844M4095
CoexpressionSHETH_LIVER_CANCER_VS_TXNIP_LOSS_PAM4

HLA-C BAD HLA-E ZEB2 SLC22A7 HOXC9 UGT2B4 UGT2B7 UGT2B28 UGT2B11 TSPYL4

2.33e-0533018411MM1120
ToppCellControl-CD8+_Tem|Control / Disease condition and Cell class

HLA-C ARHGAP26 HLA-E ZNF683 ZEB2 PTPRC GBP5 ATXN1 AHNAK

1.28e-0719518497503b3e032f95b350a2782d28e4d412a8dc9ebcc
ToppCellRSV-Healthy-1|Healthy / Virus stimulation, Condition and Cluster

HLA-C SIGLEC9 ZNF683 UBA7 GBP5 AHNAK TOR1AIP1 SLX4

6.97e-071751848ff3a27f512a3a710ebc863b7b75cce8167d5440b
ToppCellRSV-Healthy-1|RSV / Virus stimulation, Condition and Cluster

HLA-C SIGLEC9 ZNF683 UBA7 GBP5 AHNAK TOR1AIP1 SLX4

6.97e-071751848ca52b99b03535a5b3a2751d6981708dc5b255b91
ToppCellMultiple_Sclerosis-Lymphocyte-T_NK-gdT|Multiple_Sclerosis / Disease, Lineage and Cell Type

IL12RB2 HLA-C HLA-E ZNF683 HOXA11 PTPRC GBP5 SLC4A10

8.26e-071791848ab8d8104b38603ec7fbc5b35d7149e71ad57c43a
ToppCellLPS-IL1RA-Endothelial-Epi-like-Gen_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HECW1 KMT5C ZNF213 PTPRU PEAK3 ARSL ADAMTS14

1.01e-0612718476b24630978eb0772b4cd3bf59e5bc4390be47619
ToppCellcontrol-Lymphoid-CTL|Lymphoid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

HLA-C DAPK2 HLA-E ZNF683 PTPRC GBP5 ATXN1 AHNAK

1.45e-06193184889d407a88b5956559a589425b89b3eb8dc78e1dd
ToppCellCOVID-19_Severe-CD8+_Tem|COVID-19_Severe / Disease condition and Cell class

HLA-C ARHGAP26 HLA-E ZNF683 ZEB2 PTPRC GBP5 AHNAK

1.57e-061951848ff7ae62393e1c858a10592db8e6d9f36b8bae396
ToppCellmild-Lymphocytic-CD8_T_cells|Lymphocytic / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

HLA-C HLA-E ZNF683 ZEB2 PTPRC GBP5 ATXN1 AHNAK

1.70e-0619718488b0e4012e25641c3bcd3e9911031e43d9dbbff21
ToppCellParenchymal-NucSeq-Immune_Myeloid-Monocytic-Monocyte_CD14|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SEMA6B FLI1 SIGLEC9 ARHGAP26 ZEB2 SULF2 PTPRC VAV1

1.90e-062001848b4277b6faa69f20974696c7c422311f5c89e3663
ToppCelldroplet-Spleen-nan-18m-Lymphocytic-NK_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHL1 IL12RB2 ARHGEF5 DAPK2 SULF2 AHNAK ADAMTS14

6.23e-061671847aef22535a76e93472bcedacbb2c6991f3c9c8cd5
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Mesenchymal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C12orf71 MYLK AXL ARHGEF5 ADAMTS9 PLCD1 ADAMTS14

9.45e-0617818477467e5ab2fcb39cc4a2c7dd69722c91def3b6aea
ToppCellGlobus_pallidus-Macroglia-OLIGODENDROCYTE-O1|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

PLIN4 DAPK2 SHBG PEX5L SSPOP SLC4A5

9.72e-061181846d0dd5c882cd9e0a5eb0cb08e47877292126bd4ae
ToppCellGlobus_pallidus-Macroglia-OLIGODENDROCYTE-O1-Trf|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

PLIN4 DAPK2 SHBG PEX5L SSPOP SLC4A5

9.72e-0611818464283699cb3ca7a112faa07727dfdc0b0a67fb779
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP26 FANCC SLC6A3 ADAMTS9 UGT2B7 EPHA7 DNAH11

1.09e-0518218475e1b316599436740f1b30875f0ebd33c3edfb2b6
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HECW1 OBSCN SSPOP DISP3 USH2A EPHA7 DNAH11

1.17e-0518418472cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HECW1 OBSCN SSPOP DISP3 USH2A EPHA7 DNAH11

1.17e-051841847ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HECW1 OBSCN SSPOP DISP3 USH2A EPHA7 DNAH11

1.17e-0518418472b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellCOVID-19_Severe-gd_T|COVID-19_Severe / Disease condition and Cell class

ARHGAP26 HLA-E ZNF683 ZEB2 PTPRC GBP5 AHNAK

1.17e-051841847791f1bcb954aadc63d4117c400537d036f68734d
ToppCellnormal-na-Lymphocytic_T-CytoT_GZMH+-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

HLA-C ZNF683 KDM5D ZEB2 PTPRC GBP5 AHNAK

1.21e-051851847097d628f92e13250c15b550f2fd1f4225fc07558
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP26 PAPLN IGF2BP2 BEND7 NGEF UGT2B7 EPHA7

1.26e-051861847f28d72b47624b69a580b4429e2be560a26898591
ToppCelldroplet-Skin-nan-21m-Lymphocytic-nan|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLI1 MYLK LIME1 PTPRC CTNND2 VAV1 RCN3

1.30e-05187184738d7b19fde6811f5fbf548b2464486b197476dc6
ToppCelldroplet-Skin-nan-21m-Lymphocytic|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLI1 MYLK LIME1 PTPRC CTNND2 VAV1 RCN3

1.30e-051871847ea33a5bd60b7f5f6d5b07a7f06a5a56395943641
ToppCelldroplet-Skin-nan-21m-Lymphocytic-T_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLI1 MYLK LIME1 PTPRC CTNND2 VAV1 RCN3

1.30e-0518718471dbc2c0ab85033e5de776bbfdb73ebd3a50d2cc6
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

ARHGAP26 INO80D ZEB2 TASOR2 PTPRC ANKRD11 HERC1

1.35e-051881847ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCellCOPD-Lymphoid-T_Cytotoxic|Lymphoid / Disease state, Lineage and Cell class

HLA-C DAPK2 ARHGAP26 ZNF683 ZEB2 PTPRC ATXN1

1.44e-05190184710bece40d980d37a01dae8ce887655bf9f93040c
ToppCellCD8+_Memory_T_cell-CV-7|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

IL12RB2 HLA-C ZEB2 TGFBR2 PTPRC ETNK1 AGTPBP1

1.49e-0519118479454f642c3621370fa23640b631301346b300950
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_T-CytoT_GZMH+-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

HLA-C HLA-E ZNF683 KDM5D ZEB2 PTPRC GBP5

1.54e-051921847fdc741e1846cfd8ed741b160e3c611c310c5d36d
ToppCell10x5'-lymph-node_spleen-Lymphocytic_T_CD8-Trm/em_CD8|lymph-node_spleen / Manually curated celltypes from each tissue

HLA-C ARHGAP26 HLA-E ZEB2 LIME1 PTPRC GBP5

1.54e-0519218477a122505d7adf236e0cbd9bcbc98e7c537600ca3
ToppCellCD8+_Memory_T_cell-CV-0|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

HLA-C HLA-E ZNF683 ZEB2 PTPRC ATXN1 AHNAK

1.60e-051931847995781d87a919c0380750878bafe584342bb83ad
ToppCellIPF-Lymphoid-T_Cytotoxic|Lymphoid / Disease state, Lineage and Cell class

HLA-C DAPK2 ARHGAP26 ZNF683 ZEB2 PTPRC ATXN1

1.60e-0519318473c8a022dbd4f8d25b14fd137ce64c2713a7dbe41
ToppCell(1)_T_cells-(1)_T_CD8_activated|(1)_T_cells / Spleen cell shreds - cell class (v1) and cell subclass (v1)

HLA-C HLA-E ZNF683 ZEB2 PTPRC GBP5 ATXN1

1.65e-051941847e3f288b58525c1f34db4459d3e83e0df695adfc7
ToppCell(1)_T_CD8_CTL|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)

HLA-C HLA-E ZNF683 ZEB2 PTPRC GBP5 AHNAK

1.71e-051951847f582b854e5a4c52764aad5abe4e28ea77a7445f7
ToppCellChildren_(3_yrs)-Immune-monocyte-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

SEMA6B FLI1 SIGLEC9 ARHGAP26 ZEB2 PTPRC VAV1

1.71e-05195184781a28289eda1a8a1a31b7357106f64ac5000e172
ToppCellChildren_(3_yrs)-Immune-monocyte|Children_(3_yrs) / Lineage, Cell type, age group and donor

FLI1 ARHGAP26 ZEB2 SULF2 PTPRC VAV1 AGTPBP1

1.76e-051961847cacd69be72e6167814f7adea7c5fa114f3103bbb
ToppCellFetal_29-31_weeks-Immune-monocyte|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

FLI1 SIGLEC9 ARHGAP26 ZEB2 SULF2 PTPRC VAV1

1.82e-05197184748a8169a4d33c6a68d66bcd936861c75cb4b60ef
ToppCellTracheal-NucSeq-Immune_Myeloid-Macrophage_other-Macrophage_intravascular|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FLI1 IL12RB2 RENBP ZEB2 PTPRC VAV1 RCN3

1.94e-0519918479545ac59c8d75f5747dff86cb511a149dc103b31
ToppCell10x_5'_v1|World / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

HLA-C HLA-E ZNF683 LIME1 PTPRC GBP5 AHNAK

1.94e-0519918470478eafaa2a4819d1bbfb227e6c00d3578429bed
ToppCellCaecum-T_cell-CD8_T|Caecum / Region, Cell class and subclass

HLA-C DAPK2 HLA-E ZNF683 ZEB2 PTPRC GBP5

2.01e-0520018478c0ced6cbfde40c2a9b54953c6fe93d83ad001d7
ToppCellCOVID-19_Moderate-CD4+_CTL|COVID-19_Moderate / disease group, cell group and cell class

HLA-C HLA-E ZNF683 ZEB2 PTPRC GBP5 AHNAK

2.01e-052001847a9c73559e2c9fda1b065bfb5ce84978995505924
ToppCellsevere-CD8+_Tem|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

HLA-C HLA-E ZNF683 ZEB2 PTPRC GBP5 AHNAK

2.01e-052001847aaa2cd326dc15dee2fd975ca133359c5826f6a75
ToppCellCaecum-(1)_T_cell-(10)_CD8_T|Caecum / shred on region, Cell_type, and subtype

HLA-C DAPK2 HLA-E ZNF683 ZEB2 PTPRC GBP5

2.01e-0520018474276d8e21a1bb3cf51f238455bb072a7600f9253
ToppCellMS-Multiple_Sclerosis-Lymphocyte-T/NK-gd_T|Multiple_Sclerosis / Disease, condition lineage and cell class

IL12RB2 HLA-C HLA-E ZNF683 PTPRC GBP5 SLC4A10

2.01e-052001847498a2632b111fbf2cd4d755e53698ac5573ba763
ToppCellGlobus_pallidus-Macroglia-OLIGODENDROCYTE-O1-Trf-Oligodendrocyte.Trf.Il33_(Il33)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

PLIN4 DAPK2 SHBG PEX5L SLC4A5

3.05e-05871845f04125fdfa102c0ab30c2fbff874de3bc2edc3af
ToppCellGlobus_pallidus-Macroglia-OLIGODENDROCYTE-O1-Trf-Oligodendrocyte.Trf.Il33_(Il33)-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

PLIN4 DAPK2 SHBG PEX5L SLC4A5

3.05e-058718458794ac69e8db0c396c0cfc3ee303550c18a6442d
ToppCell390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0.5|390C / Donor, Lineage, Cell class and subclass (all cells)

FLI1 HLA-C HLA-E ZNF683 SSPOP PTPRC

3.79e-051501846fdbfc8f743cf848978cf0488493f6df60be53982
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP26 PEAK3 FANCC UGT2B7 EPHA7 DNAH11

4.23e-051531846d6526d17826470534b766df144c74e73eb83fdad
ToppCellfacs-Liver-Non-hepatocytes-3m-Lymphocytic-NK_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL12RB2 B3GALT6 SULF2 SLC25A53 ADAMTS14 SLX4

4.39e-05154184675eac6970259a6916fcfa6d3400509cfa2d98d9d
ToppCellControl-Epithelial_alveolar-AT_2-Differentiating_AT1|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DAPK2 LRFN3 PTPRU PLEKHG4B CFAP61 SLX4

4.88e-0515718464766f7d545bf2d775390589460677519cb92f4d5
ToppCellfrontal_cortex-Non-neuronal-smooth_muscle_cell|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PLIN4 MYLK AXL AHNAK ADAMTS14 RCN3

5.06e-05158184608806240228c5b780f5aef92ce2c278ae4d797cc
ToppCellfrontal_cortex-Non-neuronal-smooth_muscle_cell-SMC-SMC_Acta2|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PLIN4 MYLK AXL AHNAK ADAMTS14 RCN3

5.06e-051581846496b6988f7b3439968351840ae22f56ffa1643f1
ToppCellfrontal_cortex-Non-neuronal-smooth_muscle_cell-SMC|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PLIN4 MYLK AXL AHNAK ADAMTS14 RCN3

5.06e-0515818465b3d30f92b619f14a7b48502170000fa5783358a
ToppCellfacs-Marrow-Granulocytes-3m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL12RB2 B4GALT7 DAPK2 SULF2 AHNAK ADAMTS14

5.24e-051591846d2de9391b00b6c47f5fe28a1bad6da2097107ee0
ToppCellfacs-Marrow-Granulocytes-3m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL12RB2 B4GALT7 DAPK2 SULF2 AHNAK ADAMTS14

5.24e-051591846da6b7f8039adc19839d6c090a0b3d68fb6445a79
ToppCellfacs-Kidney-nan-3m-Lymphocytic-T_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL12RB2 LIME1 SF3B3 PTPRC ADAMTS14 VAV1

6.02e-051631846385b24e18df5ef92108483de312d6c85a1e6d145
ToppCellfacs-Kidney-nan-3m-Lymphocytic-T_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL12RB2 LIME1 SF3B3 PTPRC ADAMTS14 VAV1

6.02e-0516318468004cc0b3428be08b89957b563cd8799f822d931
ToppCelldroplet-Fat-Scat-18m-Mesenchymal-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHL1 ANO4 PLIN4 SLC4A10 ADAMTS14 CYB5D1

6.02e-0516318461eec7f5e5fed05fa21d3f81db588f10605f08ea7
ToppCellprimary_visual_cortex-Non-neuronal-smooth_muscle_cell-SMC|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PLIN4 MYLK AXL AHNAK ADAMTS14 RCN3

6.22e-0516418469eed945e9b0c1ee5fc62724ac2bbbed4267b0678
ToppCellfacs-Marrow-T-cells-3m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL12RB2 LIME1 SULF2 AHNAK ADAMTS14 IL27RA

6.22e-051641846e712d6b89461f741dbd773ba9a27ecaddf97cbaa
ToppCellprimary_visual_cortex-Non-neuronal-smooth_muscle_cell-SMC-SMC_Acta2|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PLIN4 MYLK AXL AHNAK ADAMTS14 RCN3

6.22e-051641846f510f20e37e31b486cdd0e3f597ce4ff00877c5d
ToppCellfacs-Spleen-nan-3m-Lymphocytic-NK_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL12RB2 DAPK2 ZEB2 SULF2 AHNAK ADAMTS14

6.22e-051641846a187bd5beca017ef657ef07c006e7f94ea3b911b
ToppCelldroplet-Spleen-nan-24m-Lymphocytic-NK_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL12RB2 DAPK2 LIME1 SULF2 AHNAK ADAMTS14

6.22e-0516418467a51365bad2910c130bd952805f7a1bef51be481
ToppCellprimary_visual_cortex-Non-neuronal-smooth_muscle_cell|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PLIN4 MYLK AXL AHNAK ADAMTS14 RCN3

6.22e-0516418465c932a462cbf81d029c8d11ec3aea3191529527b
ToppCell5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-CD8-positive,_alpha-beta_T_cell-CD8_T_cells-CD8_T_cells_L.1.1.2.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MAN2B1 ZNF683 LIME1 PTPRC GBP5 PSD4

6.22e-05164184630c3c25b05a403a509b2e755c2f0878fecb10a02
ToppCellfacs-Kidney-nan-3m-Lymphocytic|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLI1 IL12RB2 SF3B3 PTPRC ADAMTS14 VAV1

6.44e-051651846ba041deb0d9c187f251493ccd4794b5f09abd5aa
ToppCellPND01-03-samps-Epithelial-Alveolar_epithelial-AT1|PND01-03-samps / Age Group, Lineage, Cell class and subclass

DAPK2 PPP1R13B BEND7 GRHL3 AGRN SLC4A5

6.44e-051651846b9b6b7b8cd65ba6948a5dd8b715cc7092e0be637
ToppCell356C-Myeloid-Macrophage-SPP1+_Macrophage_4|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

PLIN4 CFB FAM156A ZNF396 ZNF324B SLX4

6.65e-0516618468d5d09f25e8903d481c2097fed435e69d42ccdb5
ToppCell3'_v3-GI_small-bowel-Lymphocytic_T_CD8-Trm/em_CD8|GI_small-bowel / Manually curated celltypes from each tissue

HLA-C ARHGAP26 HLA-E ZEB2 PTPRC AHNAK

7.35e-05169184617568e7aacfdcd96c469bae57d5ffad04954e9bd
ToppCellnormal_Pleural_Fluid-T/NK_cells-Cytotoxic_CD8+_T|normal_Pleural_Fluid / Location, Cell class and cell subclass

HLA-C DAPK2 HLA-E ZNF683 PTPRC ATXN1

7.84e-0517118466be81c20f4e962b414afcedfe478dd59c510d1e1
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FLI1 SIGLEC9 NDST2 PEAK3 PTPRC VAV1

8.10e-051721846ef33b5e0515c6d29fb6d9a673011c1b68ef264f3
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Mesenchymal-brain_pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C12orf71 MYLK AXL ADAMTS9 PLCD1 ADAMTS14

8.36e-0517318462415b6ff49f334da570577d4e93484d024a3dbd5
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Mesenchymal-Pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C12orf71 MYLK AXL ADAMTS9 PLCD1 ADAMTS14

8.36e-0517318462acd0693a2dfe04e3c1b2125ea63efe92d13150b
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-Mes-Like-Differentiating_AT1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DAPK2 GRPR SLC6A3 PLEKHG4B DISP3

8.59e-051081845d620f07243c2628494e689bbfabc14c453f4b1f4
ToppCell356C-Myeloid-Macrophage-SPP1+_Macrophage_4|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

PLIN4 DAPK2 CFB ZNF396 SLX4

8.59e-051081845ee924deacd14ea404fda80ed633960143fd474c0
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP26 SLC6A3 UGT2B7 CFAP61 EPHA7 DNAH11

8.90e-051751846284fdc7a9d303636a637041846850d19d114861a
ToppCellPND14-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_prolif|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MAK AXL ZNF213 ABCA7 CFB SULF2

9.19e-051761846450c25ec5eeb65425f904e0a25aaafdf5682ef9c
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-Mes-Like|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DAPK2 GRPR SLC6A3 PLEKHG4B DISP3

9.37e-051101845c80d1c3df75648e2c8f6832279c2acca63d76681
ToppCelldroplet-Skin-nan-18m-Lymphocytic-nan|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLI1 ARHGAP26 SSPOP PTPRC VAV1 RCN3

9.78e-05178184612d5c6be6cfbf733e3cb02780606b3725eda7d2b
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP26 FANCC UGT2B7 SLX4 EPHA7 DNAH11

9.78e-051781846c20f050344a2e120e685e2a7fe36c6dfc1dc37b6
ToppCelldroplet-Skin-nan-18m-Lymphocytic-T_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLI1 ARHGAP26 SSPOP PTPRC VAV1 RCN3

9.78e-051781846e0769ad06f92423a3cb6c78a61da3ba5bd9b4eae
ToppCelldroplet-Skin-nan-18m-Lymphocytic|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLI1 ARHGAP26 SSPOP PTPRC VAV1 RCN3

9.78e-05178184611c2ce093b7538518c8d4497dc5b0b4da22bf1a8
ToppCell5'-GW_trimst-2-LymphNode-Hematopoietic-T_cells-TRDV2/TRGV9_gdT|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HLA-C HLA-E ZNF683 LIME1 PTPRC IL27RA

1.01e-041791846f7d3d37505893ae55065c89d957084602729decc
ToppCell367C-Lymphocytic-ILC-ILC-2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

HSPBAP1 DAPK2 PPP1R13B ZNF683 PLCD1 TMEM231

1.01e-0417918465aa8465e943b6b666c7f8b1937fcc3764bfe91f6
ToppCell3'-GW_trimst-1-LargeIntestine-Hematopoietic-T_cells|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SFTPB ZNF683 PTPRC GBP5 SLC4A10 CFAP61

1.01e-041791846e717c0079b788a3703c0a450922bd5a2bdc322a0
ToppCellnormal-na-Lymphocytic_NK-T_mait-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

HLA-C KDM5D GLP2R PTPRC GBP5 SLC4A10

1.04e-041801846e66a8a61b3576ac37de7c559d16d4ed4f7a2fc78
ToppCellICU-NoSEP-Myeloid-tDC|ICU-NoSEP / Disease, Lineage and Cell Type

AXL KMT5C DAPK2 IGSF10 TSPYL5 TMEM231

1.04e-041801846be665e801512f6aaf6b3ecb26153bbdeb24619ac
ToppCelldroplet-Kidney-nan-3m-Mesenchymal-podocyte|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHL1 AXL IGSF10 HOXA11 AHRR RCN3

1.07e-0418118460b1e7335648823b1d83bdfa878ccd44efe7bba9a
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_T_CD8-Trm/em_CD8|lymph-node_spleen / Manually curated celltypes from each tissue

HLA-C ARHGAP26 HLA-E PTPRC GBP5 ATXN1

1.10e-041821846f857b32de19240a8aca1685f7a78b4e53b04875c
ToppCellFLU-Healthy-0|FLU / Virus stimulation, Condition and Cluster

DAPK2 ZNF683 PTPRC GBP5 AHNAK IL27RA

1.14e-041831846058604ddb06b3bef131183d86b83b422dae8f6cb
ToppCellFLU-Healthy-0|Healthy / Virus stimulation, Condition and Cluster

DAPK2 ZNF683 PTPRC GBP5 AHNAK IL27RA

1.14e-0418318467a6f18246c39864479e114f698581f667fa9c600
ToppCell3'-GW_trimst-2-SmallIntestine-Hematopoietic-T_cells-SELL+_CD8_T|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HLA-C LIME1 PTPRC VAV1 IL27RA PCNT

1.17e-041841846c80acd6a81a3633d72813a77223879d0be254f93
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage-Monocyte-derived_macrophage_L.1.2.5.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SEMA6B ARHGAP26 ZEB2 AHNAK CYB5D1 AGTPBP1

1.17e-041841846d1ea2b60fb1ca1a0b809d131310c43903a9e84ce
ToppCellfacs-Liver-Non-hepatocytes-3m-Lymphocytic-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL12RB2 LIME1 PTPRC MIP SLC25A53 IL27RA

1.17e-0418418468fc047977fad38fcd26eebcc279a688efd342ed8
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Endothelial_Myeloid-Endo-Endothelial|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FLI1 ARHGEF5 HLA-E TGFBR2 AHNAK UGT2B28

1.21e-04185184603df43e9c2ce4ec24ffed8e4e2993f94ba951c8b
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Endothelial_Myeloid-Endo-Endothelial-Endo_L2-5_CLDN5|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FLI1 ARHGEF5 HLA-E TGFBR2 AHNAK UGT2B28

1.21e-041851846dbdbd6593cd98550238519746bb45fbf0617550b
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Endothelial_Myeloid-Endo|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FLI1 ARHGEF5 HLA-E TGFBR2 AHNAK UGT2B28

1.21e-041851846de2c24719946d5a37a982d816776cea7f3984c49
ToppCellwk_20-22-Hematologic_Lymphocytic-T_&_ILC-NKT2|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

IL12RB2 HLA-C ZNF683 LIME1 PTPRC IL27RA

1.21e-0418518462d95713deaa05fb3372f4337ef156027e4d8ec8a
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP26 FANCC SLC6A3 ADAMTS9 EPHA7 DNAH11

1.24e-0418618465c4ffe4e4d5536ae9f8794277fe032c693e7dd56
ToppCellSubstantia_nigra-Macroglia-OLIGODENDROCYTE-O2-Tfr-Oligodendrocyte.Tfr.Ndrg2_(Ndrg2)-|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

DAPK2 SHBG SSPOP SLC4A5

1.25e-04621844f7697057fb5568368ec7edead2bcdd25ede7627b
ToppCellSubstantia_nigra-Macroglia-OLIGODENDROCYTE-O2-Tfr-Oligodendrocyte.Tfr.Ndrg2_(Ndrg2)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

DAPK2 SHBG SSPOP SLC4A5

1.25e-0462184419867e62ca7e024572192a2654e2eb8f226bdd60
ToppCellLV-10._Endothelium_II|World / Chamber and Cluster_Paper

FLI1 HLA-C HLA-E INO80D SULF2 ADAMTS9

1.28e-0418718467876dcb4800c2e54874df3d933efb79307a64a97
ComputationalNeighborhood of HLA-C

HLA-C HLA-E PTPRC VAV1 PSD4

7.09e-05471005GNF2_HLA_C
ComputationalNeighborhood of CD48

HLA-C HLA-E PTPRC VAV1

2.08e-04321004GNF2_CD48
ComputationalNeighborhood of VAV1

HLA-C HLA-E PTPRC VAV1

3.31e-04361004GNF2_VAV1
ComputationalNeighborhood of PTPRC

FLI1 HLA-C HLA-E PTPRC VAV1

4.13e-04681005GNF2_PTPRC
DrugTetramisole hydrochloride [16595-80-5]; Down 200; 16.6uM; HL60; HT_HG-U133A

GTPBP4 MTMR1 ABCA7 SIRT5 LARP4B IGF2BP2 ABHD17B BAZ2A PLCD1 PSD4

3.98e-06198179102489_DN
Drugbenzphetamine

CYP21A2 SLC6A3 AHRR UGT2B4 UGT2B7 UGT2B28 UGT2B11 PCNT

4.66e-061191798CID000002341
DrugAC1Q6OQG

SHBG UGT2B4 UGT2B7 UGT2B28 UGT2B11

5.64e-06331795CID000009686
Drug4-methylumbelliferone

MAN2B1 NAGA KDM5D SULF2 UGT2B4 UGT2B7 UGT2B28 UGT2B11

1.00e-051321798CID003364573
Drugl-borneol

UGT2B4 UGT2B7 UGT2B28 UGT2B11 YME1L1

1.01e-05371795CID000010049
DrugC1 11-32

UGT2B4 UGT2B7 UGT2B28 UGT2B11

1.04e-05181794CID000443077
DrugC11131

UGT2B4 UGT2B7 UGT2B28 UGT2B11

1.04e-05181794CID000443076
DrugT4-G

UGT2B4 UGT2B7 UGT2B28 UGT2B11

1.31e-05191794CID000152424
Drugtestosterone glucuronide

SHBG UGT2B4 UGT2B7 UGT2B28 UGT2B11

1.69e-05411795CID000108192
Drugestriol-16-glucuronide

UGT2B4 UGT2B7 UGT2B28 UGT2B11

1.99e-05211794CID000122281
Drugandrosterone glucuronide

SHBG UGT2B4 UGT2B7 UGT2B28 UGT2B11

2.15e-05431795CID000114833
DrugKaempferol [520-18-3]; Down 200; 14uM; HL60; HT_HG-U133A

VWA8 SFTPB BAD INO80D SIRT5 UBA7 FUCA1 RCN3 IL27RA

2.40e-0519417996157_DN
DrugBenzathine benzylpenicillin [5928-84-7]; Up 200; 4.2uM; PC3; HT_HG-U133A

MAK HECW1 SFTPB PEX5L SLC22A7 ARSL PLCD1 RCN3 PSD4

2.60e-0519617994022_UP
DrugAG-028671 [847803-03-6]; Down 200; 10uM; MCF7; HT_HG-U133A

B4GALT7 SFTPB AXIN1 LARP4B BAZ2A ZNF324 VAV1 IL27RA PSD4

2.82e-0519817996587_DN
DrugMeticrane [1084-65-7]; Up 200; 14.6uM; MCF7; HT_HG-U133A

VWA8 ARHGAP26 LRFN3 TBC1D17 BAZ2A ZNF324 PLCD1 ZNF324B PSD4

2.82e-0519817991671_UP
Drugestradiol-3-glucuronide

UGT2B4 UGT2B7 UGT2B28 UGT2B11

2.91e-05231794CID000066651
Drugsalicylamide

RENBP UGT2B4 UGT2B7 UGT2B28 UGT2B11

3.70e-05481795CID000005147
Diseaseplasma clozapine-to-N-desmethylclozapine ratio measurement

UGT2B4 UGT2B7 UGT2B11

1.57e-0591713EFO_0600040
DiseaseEHLERS-DANLOS SYNDROME, SPONDYLODYSPLASTIC TYPE, 1

B4GALT7 B3GALT6

3.34e-0521712C4552003
DiseaseX-19141 measurement

UGT2B4 UGT2B7 UGT2B11

5.24e-05131713EFO_0800799
DiseaseEhlers-Danlos syndrome progeroid type

B4GALT7 B3GALT6

9.98e-0531712cv:CN030853
Diseasephosphatidylcholine 36:4 measurement

UGT2B4 UGT2B28 UGT2B11

1.46e-04181713EFO_0010382
DiseaseMeckel syndrome (is_implicated_in)

TXNDC15 TMEM231

1.99e-0441712DOID:0050778 (is_implicated_in)
Diseasecitrulline measurement

CYP21A2 GLP2R HMCN2

2.03e-04201713EFO_0009777
DiseaseX-24947 measurement

UGT2B4 UGT2B7 UGT2B11

2.72e-04221713EFO_0800910
Diseasescoliosis (implicated_via_orthology)

SSPOP ADAMTS9

3.30e-0451712DOID:0060249 (implicated_via_orthology)
Diseasedisease progression measurement

UGT2B4 UGT2B7 HERC1 UGT2B11

4.39e-04611714EFO_0008336
DiseaseEhlers-Danlos syndrome (implicated_via_orthology)

B4GALT7 B3GALT6

4.93e-0461712DOID:13359 (implicated_via_orthology)
DiseaseX-13553 measurement

SNX29P2 ARSL

4.93e-0461712EFO_0021355
Diseasegraft-versus-host disease (implicated_via_orthology)

HLA-C HLA-E

6.88e-0471712DOID:0081267 (implicated_via_orthology)
Diseasemetabolite measurement, diet measurement

CYP21A2 NCOR1 AHNAK ZKSCAN4

7.82e-04711714EFO_0004725, EFO_0008111
DiseaseColorectal Carcinoma

CHL1 OBSCN PTPRU PEX5L ZEB2 TGFBR2 HOXC9 CSE1L CTNND2 FOXH1 AGTPBP1 EPHA7

8.48e-0470217112C0009402
DiseaseEhlers-Danlos syndrome

B4GALT7 B3GALT6

9.14e-0481712cv:C0013720
Diseasevisceral heterotaxy (implicated_via_orthology)

MMP21 FOXH1 DNAH11

1.29e-03371713DOID:0050545 (implicated_via_orthology)
Diseasevitamin D deficiency

UGT2B4 UGT2B7 UGT2B11

1.29e-03371713EFO_0003762
DiseaseFamilial thoracic aortic aneurysm and aortic dissection

MYLK TGFBR2

1.46e-03101712cv:C4707243
Diseaseglutamine measurement, amino acid measurement

CYP21A2 MIP

1.77e-03111712EFO_0005134, EFO_0009768
DiseasePeptic ulcer and gastro-oesophageal reflux disease (GORD) drug use measurement

HLA-C DNAH11

1.77e-03111712EFO_0009923
Diseaseautism spectrum disorder (implicated_via_orthology)

KMT5C NDST2 KDM5D SLC6A3 CTNND2

1.97e-031521715DOID:0060041 (implicated_via_orthology)
Diseasestromal cell-derived factor 1 alpha measurement

CYP21A2 TGFBR2 NGEF

1.99e-03431713EFO_0008293
DiseaseGastrointestinal Diseases

MYLK GAST

2.12e-03121712C0017178
DiseaseFunctional Gastrointestinal Disorders

MYLK GAST

2.12e-03121712C0559031
DiseaseCholera Infantum

MYLK GAST

2.12e-03121712C1565321
Diseaseadult respiratory distress syndrome (is_implicated_in)

MYLK SFTPB

2.12e-03121712DOID:11394 (is_implicated_in)
Diseasechronic kidney disease

SFMBT1 GTPBP4 CYP21A2 LARP4B EPHA7 PSD4

2.56e-032351716EFO_0003884
DiseasePsychotic Disorders

ARHGAP26 HLA-E PTPRC PCNT

2.87e-031011714C0033975
DiseaseFanconi anemia

FANCC SLX4

2.90e-03141712cv:C0015625
DiseaseMedulloblastoma

FLI1 AXIN1 VAV1

3.07e-03501713C0025149
Diseasehigh grade glioma (biomarker_via_orthology)

BAD SLC6A3

3.34e-03151712DOID:3070 (biomarker_via_orthology)
Diseaseanemia (implicated_via_orthology)

SLC4A10 SLC4A5

3.34e-03151712DOID:2355 (implicated_via_orthology)
Diseaseidiopathic scoliosis (implicated_via_orthology)

SSPOP PRMT5

3.80e-03161712DOID:0060250 (implicated_via_orthology)
DiseaseCiliopathies

TMEM231 FOXH1 USH2A DNAH11

3.90e-031101714C4277690
Diseaseanti-anoctamin 2 antibody measurement

HLA-C CFB

4.29e-03171712EFO_0010150
DiseaseS-adenosylhomocysteine measurement

ANO4 VWA8

4.29e-03171712EFO_0010531
DiseaseNeoplasm Invasiveness

MYLK AXL SHBG ZEB2 AHNAK

4.46e-031841715C0027626
DiseaseMeckel syndrome type 1

TXNDC15 TMEM231

4.81e-03181712C3714506
DiseaseBone marrow hypocellularity

FANCC SLX4

4.81e-03181712C1855710
Diseaseasthma (biomarker_via_orthology)

DPP10 SFTPB PRMT5

4.90e-03591713DOID:2841 (biomarker_via_orthology)
Diseaseblood urea nitrogen measurement

CYP21A2 KIAA1614 DHX8 LARP4B BEND7 MIP MAMSTR PSD4

5.02e-034521718EFO_0004741

Protein segments in the cluster

PeptideGeneStartEntry
REPLDSPQWATHSQG

AHRR

661

A9YTQ3
GAWLAPVDVQREHDP

B3GALT6

246

Q96L58
AILAQWNDGLHPDPI

CFAP61

901

Q8NHU2
LPPHQAEDARTQRQW

DISP3

1266

Q9P2K9
SRGLSHLGQVEPVPW

ANKRD11

2106

Q6UB99
WEHQRTLSPVPLQLD

ARSL

546

P51690
APGLLWDASHQQEQP

BAD

41

Q92934
IATPEEVRLPLQHGW

BAZ2A

546

Q9UIF9
APLPHWRGTSLIQQS

C2orf27A

126

P0DPF5
PEHWEAVPQSLAGRQ

ARHGEF5

101

Q12774
HILPVGRIEEPFWQN

GSDMC

301

Q9BYG8
RWQVVDTPGILDHPL

GTPBP4

216

Q9BZE4
AVPVEPGQWHRLELS

AGRN

1446

O00468
PEHWEAVPQSLAGRQ

ARHGEF35

101

A5YM69
EDEKQQRWGQPHGPV

CD300LD-AS1

41

Q96MU5
LTHCERWPLVIDPQQ

DNAH11

3486

Q96DT5
INAPDVDVRGPDWHL

AHNAK

3916

Q09666
LQGPWDTITQQEHPI

ATG10

141

Q9H0Y0
QSVRLPGAWDPAAHQ

ARPIN

16

Q7Z6K5
RQEHGPERKISFPQW

ANO4

681

Q32M45
DNHRVEGTAWLPGNP

ATXN1

36

P54253
EDLNRQWQSPSPDLH

AGTPBP1

976

Q9UPW5
TPAEVAQHNRPEDLW

CYB5D1

21

Q6P9G0
VIIPHSGWENSPLQD

CTNND2

686

Q9UQB3
NIHTREVWELNPPEV

DPP10

161

Q8N608
AEVWRGNERPIPFDH

PPP1R13B

46

Q96KQ4
EGQWVPQSEPLHPIN

ADAMTS14

1041

Q8WXS8
PQLLALVQHWVPGAR

ABCA7

1076

Q8IZY2
IADGHPTPRLQWQLQ

ISLR2

261

Q6UXK2
SLRWAPGPLHVLQVA

MIP

31

P30301
GRVPVLSWIHPESQA

MTMR1

286

Q13613
LDGSEVGHWVLPPAQ

RCN3

261

Q96D15
GHWVTTEENLQLDPP

CRYZL1

256

O95825
GTQTLPARPLDHQWK

CDC42BPG

716

Q6DT37
PRHTIAPRNWGVQAE

ODF3B

121

A8MYP8
DVPPEGWNRTRHVII

CFB

371

P00751
GAPVVWSHNGRPVQE

OBSL1

1201

O75147
HWVQEDASGLGRPQL

RENBP

166

P51606
HGPEWEPVQGLLSQN

C22orf46

16

C9J442
DLDPSNPVANWIHAR

HOXC9

176

P31274
HVQHEGLPEPVTLRW

HLA-E

281

P13747
EPQVTWHRNGQPITS

MYLK

61

Q15746
NRAPHPSSWETLVQG

FAM156A

146

Q8NDB6
SIRNDIEWGVLHQPP

MID1IP1

96

Q9NPA3
EPRAWPLHLLQGTAV

FOXH1

246

O75593
TIKWRVNGSPVDNHP

CHL1

361

O00533
RELWEESGLHLPQGQ

NUDT17

141

P0C025
EALVALGQPPHARWA

KMT5C

371

Q86Y97
LPPNWEARIDSHGRV

HECW1

831

Q76N89
DLNHTLEWPLQGVPI

HMCN2

326

Q8NDA2
EDQELQWPLHGGPEL

HERC1

1106

Q15751
VEWRELHPGGDTQVP

IL12RB2

456

Q99665
LHPGGDTQVPLNWLR

IL12RB2

461

Q99665
HSIWQLLQAGQPPDL

KDM5D

1401

Q9BY66
ELPWGLQAQQHLPRA

KIAA1614

666

Q5VZ46
LNPNAEVWGAPVLHL

LARP4B

56

Q92615
EDASWGPHRLAVLVP

B4GALT7

86

Q9UBV7
PNLQGAHLDETVWER

CYP21A2

386

P08686
QHEGLQEPLTLSWEP

HLA-C

286

P10321
QILTGWPGIPTHNID

MMP21

381

Q8N119
DVPHPWGLELQASLS

PEAK3

211

Q6ZS72
VPHPAISGNIWAALR

PEX5L

581

Q8IYB4
HWPENGVLNLESPIT

FUCA1

401

P04066
QIGRVEFLPVNWHSP

DDHD2

261

O94830
GTPAIAWGEVPRHQL

IL27RA

431

Q6UWB1
PVVLGVRWLSTHDPN

PEG10

441

Q86TG7
PNWPNHTLVLLDTEG

GBP5

86

Q96PP8
HGATAALVQWPDQRP

LRFN3

436

Q9BTN0
IRNIPPHLQWEVLDG

IGF2BP2

86

Q9Y6M1
AIEPATKWHPRGNLA

HOXA11

66

P31270
SGIPNLGVWPNRIHT

METTL15

21

A6NJ78
LSWQEPEHPNGVITE

EPHA7

461

Q15375
WLEQPESHQRLAGPG

MED26

341

O95402
RLEPSEGHSQELPWV

PCNT

636

O95613
IELFGRPHNVQPNWI

METTL3

531

Q86U44
WEQVRIHPGTRAPAD

PTPRU

51

Q92729
IAPSPADAQHWVLGL

PLCD1

111

P51178
VPVGPVHWLRNQEEV

OBSCN

446

Q5VST9
SREHQWPIGLKEPQI

FANCD2OS

131

Q96PS1
RAEGNPKPEIIWIHN

PXDNL

256

A1KZ92
DLELPWLEQQGPASH

GAST

41

P01350
QVQGRKRWHLFPPED

HSPBAP1

186

Q96EW2
HFNINGLLPNVRWVP

ADAMTS9

661

Q9P2N4
EAVGNPLPTIHWTRV

IGSF10

1671

Q6WRI0
GELGAQPQQDHARWP

GLP2R

511

O95838
ESIHGVPPTQRWQPD

GRHL3

181

Q8TE85
IQEALRHPWITPVDN

DAPK2

276

Q9UIK4
PINSEELFVHPLWNR

CELA3A

101

P09093
EHPWAGPQLRTSVQP

AXIN1

671

O15169
NPWPNVDAHSGVLLQ

CS

396

O75390
ADLPVNDDWSHPGIL

GRPR

26

P30550
VPADPTLWTQEHVRQ

FLI1

126

Q01543
VLLQDPQDIPRGHWL

FANCC

351

Q00597
EPTPFWVPNNGVHDR

GLB1L

426

Q6UWU2
WQHISFQALPPELRE

C1orf112

531

Q9NSG2
DLPSNHVIDRWLGEP

PRMT5

211

O14744
ANETWLVTGRHPLPV

BRF2

211

Q9HAW0
NRAQPIPSVHGRTDW

MAK

601

P20794
GQRHLELEWSVGPIP

MAN2B1

706

O00754
HRRNQEQISDPDPWI

MAMSTR

26

Q6ZN01
LEVPLGGVVNPRTHW

INO80D

876

Q53TQ3
PQSLHPSSRGVWNEL

BEND7

106

Q8N7W2
HWVRPLAEVLVPDSQ

C2orf81

351

A6NN90
VARAWPGDPQEVRHL

LINC02913

106

Q8NAJ2
EPLRPREGLWSHVDQ

EMILIN3

716

Q9NT22
LQHLRPHWDPQEVTL

ETNK1

126

Q9HBU6
QDVWLEAHLPREPDG

SLC22A7

61

Q9Y694
SLQHEGQEGQWPPRD

PRRT3

171

Q5FWE3
PPHVLVNWAVQIARG

MAP3K11

211

Q16584
NKHWVDPLPDAEGRQ

DHX8

506

Q14562
WNPGSLQPQHTVRSL

LRCH2

66

Q5VUJ6
TNPLEWPERHVLQNL

MTBP

551

Q96DY7
PGLEESQHWIALPLG

OR52L1

36

Q8NGH7
PGLEESQHWIALPLG

OR52L2P

36

Q8NGH6
EQLLEGLQHNPPLSW

PLIN4

1331

Q96Q06
AGVQWHDLSSLQPLP

SNX29P2

231

Q8IUI4
TLQAAPEGVWVTPRH

USH2A

3676

O75445
PTLQGRDWVPLHSGE

SYT15

81

Q9BQS2
AQPGQLLHWPREGLA

SSPOP

2291

A2VEC9
QHTPQLLTLVPRGWD

SFTPB

341

P07988
EVGWDLEPLINPERH

FAM183A

91

A6NL82
PLGSQLSDQHPLTWR

PRDM15

1456

P57071
TGRREPWLLPSQHND

GANAB

681

Q14697
PWLLPSQHNDIIRDA

GANAB

686

Q14697
NREWEVLQPAPHQVI

NCOR1

1001

O75376
QRAPRGIPSWNDHEP

SPATA31A7

896

Q8IWB4
HPIPADSWRNLIEQI

NGEF

161

Q8N5V2
GWRLEHENPSDPQTP

PITRM1

181

Q5JRX3
QNVPPWGSGVELTHL

PSD4

61

Q8NDX1
VHPSQEPGWLEGTLN

ARHGAP26

786

Q9UNA1
QGWALRPVLPTQSAH

SHBG

26

P04278
LIHWRVLGPQDSPEE

SMIM33

91

A0A1B0GW64
NPGVLELPWVHLRDA

SIGLEC9

301

Q9Y336
GRPEIPSFWLNHQGI

TGFBR2

496

P37173
DGLAEQGLPHWVPAL

SLC25A53

201

Q5H9E4
LPQPSRHQEIWSILE

SWT1

746

Q5T5J6
QGLPPSHRVIWLQSV

RIC8A

56

Q9NPQ8
IPIDHWNLERTGPLS

SLX4

1436

Q8IY92
QRPVEPLWVEGAGHN

ABHD17B

251

Q5VST6
IHFLPPVQGAWGTER

C12orf71

51

A8MTZ7
LPLAQVSAHPWVRAN

AURKB

316

Q96GD4
QRAPRGIPSWNDHEP

SPATA31A3

896

Q5VYP0
DEAVPSLGHAPWILR

SEMA6B

406

Q9H3T3
WARHVGPEGRLQQVP

TBC1D17

286

Q9HA65
TNLEGWVGHPLDPID

ZSWIM5

596

Q9P217
FPHLLQPVLWERTGN

CSE1L

686

P55060
AVWQEPHRLLGGQEP

ZNF324

226

O75467
IWPQHTAVNPRLLEN

nan

6

Q6ZUT4
WSRISHLVLPVQPEN

TOR1AIP1

561

Q5JTV8
HWASPELRQNPGVKN

SEC16A

311

O15027
QRAPRGIPSWNDHEP

SPATA31A5

896

Q5VU36
AGWSPEKQAQHLPLR

UBA7

956

P41226
EWQRDGQPVSSPRHQ

PAPLN

1076

O95428
WIPQNDLLGHPKTRA

UGT2B4

356

P06133
SDVPARQPHPEQEGW

PLEKHG4B

161

Q96PX9
QTELQDPHPSRELPW

TMC4

81

Q7Z404
VLPPSHRVTWDGAQV

VAV1

16

P15498
QSHGIDDLGPPRWQL

SLC6A3

226

Q01959
EPHNPSNGTLKEWRE

SLC4A10

671

Q6U841
RLWSEEQPAHPLQVG

TXNDC15

41

Q96J42
NESHLLPRGPGWVNL

SEPTIN12

316

Q8IYM1
QGEPPEVHWLRDGQI

AXL

61

P30530
VHWQEPRAPLQGTLL

AXL

351

P30530
LSTPIRWHRGQDPQA

TSPYL4

326

Q9UJ04
GQPVPSWLREELQHS

NDST2

866

P52849
KVHWGLRPDQPQQEL

SLC4A5

56

Q9BY07
WIPQNDLLGHPKTRA

UGT2B11

356

O75310
ELPGNPNAVWTVRRH

SF3B3

451

Q15393
PTLGHVSLLPENDRW

YME1L1

626

Q96TA2
PGNLQSWVREQHPES

ZKSCAN4

106

Q969J2
ILPGELRVWVQLHNP

ZNF445

106

P59923
FSLPPNVHQRTWIGD

ZNF121

71

P58317
LNDPNPIWLVGRAAD

TMEM231

226

Q9H6L2
VLPGEIQGWVREQHP

ZNF213

96

O14771
PPSAIRHLKNEAEWQ

SFMBT1

231

Q9UHJ3
VRALHGPWNTDLPDN

TASOR2

771

Q5VWN6
GTVRIWGPAPFIDHQ

WDR26

636

Q9H7D7
VGIPLFWDQPDNIAH

UGT2B28

391

Q9BY64
WIPQNDLLGHPKTRA

UGT2B7

356

P16662
PWHNNEILQASVDGP

ZEB2

96

O60315
QDSPGPHEALSRLWE

ZNF396

61

Q96N95
WGQEPPALVHRNRDT

TSPY26P

276

Q9H489
LAEPPVIGSTAHQWL

VWA8

581

A3KMH1
LRPHVVWFGENLDPA

SIRT5

216

Q9NXA8
RSEAAHQGVITWNPP

PTPRC

401

P08575
LQSPAWPRHAGVAQE

C16orf82

101

Q7Z2V1
WPRHAGVAQEPLKVS

C16orf82

106

Q7Z2V1
NLTKRHWPGAPEDQD

SULF2

561

Q8IWU5
EPWNVKRQEAADGHP

ZNF195

61

O14628
SPPVLIAWDNQGLLH

ZP4

51

Q12836
NELGHPSARWETLLP

ZNF683

241

Q8IZ20
LLEVPRHPGWGQQSA

nan

166

Q6ZTC4
TPIQWLPGHDLQSLS

TSPYL5

326

Q86VY4
AAWQEPHRLLGGQEP

ZNF324B

226

Q6AW86
PHWLEVSRDITGPQA

LIME1

101

Q9H400
WFVEHQDILQPVAGP

NAGA

231

P17050