Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionalpha-tocopherol omega-hydroxylase activity

CYP4F8 CYP4F2 CYP4F3 CYP4F12

2.20e-095934GO:0052871
GeneOntologyMolecularFunctionleukotriene-B4 20-monooxygenase activity

CYP4F8 CYP4F2 CYP4F3 CYP4F12

1.53e-087934GO:0050051
GeneOntologyMolecularFunctionalkane 1-monooxygenase activity

CYP4F8 CYP4F2 CYP4F3 CYP4F12

1.53e-087934GO:0018685
GeneOntologyMolecularFunctionarachidonate omega-hydroxylase activity

CYP4F8 CYP4F2 CYP4F3 CYP4F12

9.06e-0810934GO:0052869
GeneOntologyMolecularFunctionfatty acid omega-hydroxylase activity

CYP4F8 CYP4F2 CYP4F3 CYP4F12

9.06e-0810934GO:0120250
GeneOntologyMolecularFunctionlong-chain fatty acid omega-hydroxylase activity

CYP4F8 CYP4F2 CYP4F3 CYP4F12

9.06e-0810934GO:0102033
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen

CYP4F8 CYP4F2 CYP4F3 CYP4F12

3.05e-0713934GO:0016713
GeneOntologyMolecularFunctionlipid binding

SYT15 PCYT1A SNX14 CLIP3 CYP4F8 SH3PXD2A NISCH PCLO SYT14 APBA1 PLA2G4A CYP4F2 PLCB2 CYP4F12 MCF2L F10 PRLR HDLBP

5.86e-079889318GO:0008289
GeneOntologyMolecularFunctionarachidonate epoxygenase activity

CYP4F8 CYP4F2 CYP4F3 CYP4F12

4.36e-0624934GO:0008392
GeneOntologyMolecularFunctionarachidonate monooxygenase activity

CYP4F8 CYP4F2 CYP4F3 CYP4F12

7.13e-0627934GO:0008391
GeneOntologyMolecularFunctionphospholipid binding

SYT15 PCYT1A SNX14 SH3PXD2A NISCH PCLO SYT14 APBA1 PLA2G4A PLCB2 MCF2L F10

8.93e-065489312GO:0005543
GeneOntologyMolecularFunctionaromatase activity

CYP4F8 CYP4F2 CYP4F3 CYP4F12

2.07e-0535934GO:0070330
GeneOntologyMolecularFunction20-hydroxy-leukotriene B4 omega oxidase activity

CYP4F2 CYP4F3

2.15e-052932GO:0097258
GeneOntologyMolecularFunction20-aldehyde-leukotriene B4 20-monooxygenase activity

CYP4F2 CYP4F3

2.15e-052932GO:0097259
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen

CYP4F8 CYP4F2 CYP4F3 CYP4F12

3.54e-0540934GO:0016709
GeneOntologyMolecularFunctionarachidonate binding

CYP4F8 CYP4F2 CYP4F12

4.27e-0515933GO:0050544
GeneOntologyMolecularFunctionmolecular function activator activity

BLM PPP4R3B CACNA1S SEMA3D PTTG3P PTTG1 IL16 KITLG SH3PXD2A RALGAPB WNT10A CHGB GNAS EDA ARHGAP21 PLXNB1 PTTG2

4.88e-0512339317GO:0140677
GeneOntologyMolecularFunctionicosanoid binding

CYP4F8 CYP4F2 CYP4F12

5.24e-0516933GO:0050542
GeneOntologyMolecularFunctionicosatetraenoic acid binding

CYP4F8 CYP4F2 CYP4F12

5.24e-0516933GO:0050543
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen

CYP4F8 CYP4F2 CYP4F3 CYP4F12

7.96e-0549934GO:0016712
GeneOntologyMolecularFunctioncalcium-dependent phospholipid binding

SYT15 PCLO SYT14 PLA2G4A

1.76e-0460934GO:0005544
GeneOntologyMolecularFunctionadrenergic receptor binding

MAGI2 APLP1 GNAS

1.84e-0424933GO:0031690
GeneOntologyMolecularFunction3'-5' exonuclease activity

PNPT1 EXOSC10 POLE PAN2

1.88e-0461934GO:0008408
GeneOntologyMolecularFunctionexonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters

PNPT1 EXOSC10 POLE PAN2

2.00e-0462934GO:0016796
GeneOntologyMolecularFunctionlong-chain fatty acid binding

CYP4F8 CYP4F2 CYP4F12

2.94e-0428933GO:0036041
GeneOntologyMolecularFunction3'-5'-RNA exonuclease activity

PNPT1 EXOSC10 PAN2

6.78e-0437933GO:0000175
GeneOntologyMolecularFunctioncalcium ion binding

SYT15 CELSR1 PCLO CAPN3 PKD2L1 PLA2G4A PRRG3 PLCB2 RET IDS F10

7.14e-047499311GO:0005509
GeneOntologyMolecularFunctionRNA polymerase II complex binding

PCF11 GTF2B PAF1

7.92e-0439933GO:0000993
GeneOntologyMolecularFunctionRNA exonuclease activity, producing 5'-phosphomonoesters

PNPT1 EXOSC10 PAN2

8.53e-0440933GO:0016896
GeneOntologyMolecularFunctionexonuclease activity

PNPT1 EXOSC10 POLE PAN2

9.01e-0492934GO:0004527
GeneOntologyMolecularFunctioncysteine-type endopeptidase inhibitor activity

PTTG3P PTTG1 PTTG2

1.05e-0343933GO:0004869
GeneOntologyMolecularFunctionguanylate kinase activity

PALS1 CASK

1.15e-0311932GO:0004385
GeneOntologyMolecularFunctionRNA exonuclease activity

PNPT1 EXOSC10 PAN2

1.20e-0345933GO:0004532
GeneOntologyMolecularFunctionRNA polymerase core enzyme binding

PCF11 GTF2B PAF1

1.20e-0345933GO:0043175
GeneOntologyMolecularFunctionmonooxygenase activity

CYP4F8 CYP4F2 CYP4F3 CYP4F12

2.06e-03115934GO:0004497
GeneOntologyMolecularFunctionamide binding

CLIP3 CALCR APBA1 PLA2G4A GRIN2A PRLR

2.75e-03299936GO:0033218
GeneOntologyMolecularFunctioncalcium channel activity

CACNA1S PKD2L1 GRIN2A CNGA2

3.12e-03129934GO:0005262
GeneOntologyMolecularFunctionRNA polymerase binding

PCF11 GTF2B PAF1

3.47e-0365933GO:0070063
GeneOntologyMolecularFunctionphosphatidylinositol binding

SNX14 SH3PXD2A NISCH APBA1 PLA2G4A MCF2L

3.61e-03316936GO:0035091
GeneOntologyMolecularFunctionbasal RNA polymerase II transcription machinery binding

PCF11 GTF2B PAF1

3.62e-0366933GO:0001099
GeneOntologyMolecularFunctionbasal transcription machinery binding

PCF11 GTF2B PAF1

3.62e-0366933GO:0001098
GeneOntologyMolecularFunctionRNA nuclease activity

PNPT1 EXOSC10 PAN2 DICER1

3.76e-03136934GO:0004540
GeneOntologyMolecularFunctionceramide binding

CLIP3 PLA2G4A

3.86e-0320932GO:0097001
GeneOntologyMolecularFunctionfatty acid binding

CYP4F8 CYP4F2 CYP4F12

4.10e-0369933GO:0005504
GeneOntologyMolecularFunctioncalmodulin binding

PCYT1A CACNA1S KCNQ2 CNGA2 CASK

4.44e-03230935GO:0005516
GeneOntologyMolecularFunctionnuclease activity

PNPT1 EXOSC10 POLE PAN2 DICER1

4.52e-03231935GO:0004518
GeneOntologyMolecularFunctionsemaphorin receptor binding

SEMA3D PLXNB1

5.09e-0323932GO:0030215
GeneOntologyMolecularFunctionnucleoside monophosphate kinase activity

PALS1 CASK

5.09e-0323932GO:0050145
GeneOntologyMolecularFunctionphosphatidylinositol-5-phosphate binding

SH3PXD2A PLA2G4A

5.09e-0323932GO:0010314
GeneOntologyMolecularFunctioncalcium ion transmembrane transporter activity

CACNA1S PKD2L1 GRIN2A CNGA2

5.45e-03151934GO:0015085
GeneOntologyMolecularFunctionvoltage-gated monoatomic cation channel activity

CACNA1S KCNQ2 GRIN2A CNGA2

5.58e-03152934GO:0022843
GeneOntologyBiologicalProcessleukotriene B4 catabolic process

CYP4F8 CYP4F2 CYP4F3 CYP4F12

5.05e-096904GO:0036101
GeneOntologyBiologicalProcessleukotriene B4 metabolic process

CYP4F8 CYP4F2 CYP4F3 CYP4F12

1.17e-087904GO:0036102
GeneOntologyBiologicalProcessleukotriene catabolic process

CYP4F8 CYP4F2 CYP4F3 CYP4F12

2.34e-088904GO:0036100
GeneOntologyBiologicalProcessicosanoid catabolic process

CYP4F8 CYP4F2 CYP4F3 CYP4F12

1.09e-0711904GO:1901523
GeneOntologyBiologicalProcesslong-chain fatty acid catabolic process

CYP4F8 CYP4F2 CYP4F3 CYP4F12

1.63e-0712904GO:0042758
GeneOntologyBiologicalProcessleukotriene metabolic process

CYP4F8 PLA2G4A CYP4F2 CYP4F3 CYP4F12

9.36e-0741905GO:0006691
GeneOntologyBiologicalProcessfatty acid derivative catabolic process

CYP4F8 CYP4F2 CYP4F3 CYP4F12

2.33e-0622904GO:1901569
GeneOntologyBiologicalProcessneural crest cell differentiation

SEMA3D KITLG WNT10A MAPK1 RET DICER1

6.28e-06104906GO:0014033
GeneOntologyBiologicalProcesssister chromatid cohesion

GTF2B PTTG3P PTTG1 SMC1A PTTG2

1.10e-0567905GO:0007062
GeneOntologyBiologicalProcessarachidonate metabolic process

CYP4F8 PLA2G4A CYP4F2 CYP4F3 CYP4F12

1.19e-0568905GO:0019369
GeneOntologyBiologicalProcesshair follicle development

CELSR1 WNT10A GNAS EDA NSUN2 DICER1

1.65e-05123906GO:0001942
GeneOntologyBiologicalProcessorganic hydroxy compound catabolic process

CYP4F8 CYP4F2 CYP4F3 CYP4F12 ADH1B

1.68e-0573905GO:1901616
GeneOntologyBiologicalProcessmitotic sister chromatid cohesion

PTTG3P PTTG1 SMC1A PTTG2

1.79e-0536904GO:0007064
GeneOntologyBiologicalProcessmolting cycle process

CELSR1 WNT10A GNAS EDA NSUN2 DICER1

1.89e-05126906GO:0022404
GeneOntologyBiologicalProcesshair cycle process

CELSR1 WNT10A GNAS EDA NSUN2 DICER1

1.89e-05126906GO:0022405
GeneOntologyBiologicalProcessomega-hydroxylase P450 pathway

CYP4F8 CYP4F2 CYP4F12

2.82e-0514903GO:0097267
GeneOntologyBiologicalProcessmonocarboxylic acid catabolic process

HEXA CYP4F8 CYP4F2 CYP4F3 CYP4F12 IDS

4.17e-05145906GO:0072329
GeneOntologyBiologicalProcessneural crest cell development

SEMA3D KITLG MAPK1 RET DICER1

4.40e-0589905GO:0014032
GeneOntologyBiologicalProcessmolting cycle

CELSR1 WNT10A GNAS EDA NSUN2 DICER1

5.04e-05150906GO:0042303
GeneOntologyBiologicalProcesshair cycle

CELSR1 WNT10A GNAS EDA NSUN2 DICER1

5.04e-05150906GO:0042633
GeneOntologyBiologicalProcessmenaquinone catabolic process

CYP4F2 CYP4F12

5.63e-053902GO:0042361
GeneOntologyBiologicalProcesstRNA decay

EXOSC10 NSUN2 DICER1

6.25e-0518903GO:0016078
GeneOntologyBiologicalProcessstem cell development

SEMA3D KITLG MAPK1 RET DICER1

8.05e-05101905GO:0048864
GeneOntologyBiologicalProcessskin epidermis development

CELSR1 WNT10A GNAS EDA NSUN2 DICER1

8.84e-05166906GO:0098773
GeneOntologyBiologicalProcessmenaquinone metabolic process

CYP4F2 CYP4F12

1.12e-044902GO:0009233
GeneOntologyBiologicalProcessneuroligin clustering involved in postsynaptic membrane assembly

MAGI2 NRXN2

1.12e-044902GO:0097118
GeneOntologyBiologicalProcessphylloquinone metabolic process

CYP4F2 CYP4F12

1.12e-044902GO:0042374
GeneOntologyBiologicalProcessphylloquinone catabolic process

CYP4F2 CYP4F12

1.12e-044902GO:0042376
GeneOntologyBiologicalProcessvitamin K catabolic process

CYP4F2 CYP4F12

1.12e-044902GO:0042377
GeneOntologyBiologicalProcessolefinic compound metabolic process

CYP4F8 PLA2G4A CYP4F2 CYP4F3 CYP4F12 ADH1B

1.38e-04180906GO:0120254
GeneOntologyBiologicalProcessdermatan sulfate catabolic process

HEXA IDS

1.87e-045902GO:0030209
GeneOntologyBiologicalProcesssynapse organization

RHOB MAGI2 CACNA1S NRXN2 PCLO IGSF9 SORBS1 GRIN2A ADNP PLXNB1 CASK

1.92e-046859011GO:0050808
GeneOntologyBiologicalProcesslong-chain fatty acid metabolic process

CYP4F8 PLA2G4A CYP4F2 CYP4F3 CYP4F12

2.12e-04124905GO:0001676
GeneOntologyBiologicalProcesscell division

PIK3R4 BLM RHOB YEATS2 PTTG3P PTTG1 SMC1A NSUN2 DICER1 PTTG2 KNL1

2.23e-046979011GO:0051301
GeneOntologyBiologicalProcessunsaturated fatty acid metabolic process

CYP4F8 PLA2G4A CYP4F2 CYP4F3 CYP4F12

2.45e-04128905GO:0033559
GeneOntologyBiologicalProcessvitamin E metabolic process

CYP4F2 CYP4F12

2.79e-046902GO:0042360
GeneOntologyBiologicalProcessprostaglandin catabolic process

CYP4F2 CYP4F12

2.79e-046902GO:1905344
GeneOntologyBiologicalProcesshair follicle placode formation

GNAS EDA

2.79e-046902GO:0060789
GeneOntologyBiologicalProcessprostanoid catabolic process

CYP4F2 CYP4F12

2.79e-046902GO:0062232
GeneOntologyBiologicalProcesshomologous chromosome segregation

PTTG3P PTTG1 PTTG2 KNL1

3.78e-0478904GO:0045143
GeneOntologyBiologicalProcessstem cell differentiation

SEMA3D KITLG WNT10A MAPK1 RET NSUN2 DICER1

3.85e-04306907GO:0048863
GeneOntologyBiologicalProcessicosanoid metabolic process

CYP4F8 PLA2G4A CYP4F2 CYP4F3 CYP4F12

3.96e-04142905GO:0006690
GeneOntologyBiologicalProcessfatty acid derivative metabolic process

CYP4F8 CYP4F2 CYP4F3 CYP4F12

4.57e-0482904GO:1901568
GeneOntologyBiologicalProcessresponse to auditory stimulus

NEUROG1 NRXN2 KCNQ2

5.61e-0437903GO:0010996
GeneOntologyBiologicalProcesssmall GTPase-mediated signal transduction

RHOB CELSR1 KITLG NISCH RALGAPB GRIN2A MCF2L ARHGAP21 PLXNB1

5.67e-04538909GO:0007264
GeneOntologyBiologicalProcessmodulation of chemical synaptic transmission

SNX14 NRXN2 NISCH PCLO APBA1 KCNQ2 GRIN2A MAPK1 ADNP CASK

6.22e-046639010GO:0050804
GeneOntologyBiologicalProcessregulation of trans-synaptic signaling

SNX14 NRXN2 NISCH PCLO APBA1 KCNQ2 GRIN2A MAPK1 ADNP CASK

6.30e-046649010GO:0099177
GeneOntologyBiologicalProcessregulation of body fluid levels

NEUROG1 ADAMTS18 PLA2G4A CYP4F2 CYP4F12 GNAS F10 PRLR

6.98e-04442908GO:0050878
GeneOntologyBiologicalProcessdermatan sulfate metabolic process

HEXA IDS

8.28e-0410902GO:0030205
GeneOntologyBiologicalProcessmeiotic cell cycle

PTTG3P PTTG1 SMC1A NSUN2 DICER1 PTTG2 KNL1

8.54e-04350907GO:0051321
GeneOntologyBiologicalProcessgrowth

MAGI2 PNPT1 PTTG3P PTTG1 RPS6KA3 CAPN3 APBA1 DERL2 MAPK1 GNAS ADNP DICER1 PRLR PTTG2

8.90e-0412359014GO:0040007
GeneOntologyBiologicalProcessRNA 3'-end processing

PCF11 PNPT1 EXOSC10 PAF1

8.96e-0498904GO:0031123
GeneOntologyBiologicalProcessmaintenance of location in cell

HEXA CACNA1S ANKRD13C CAPN3 PLCB2 ARHGAP21

9.55e-04259906GO:0051651
GeneOntologyBiologicalProcessmeiotic cell cycle checkpoint signaling

NSUN2 KNL1

1.01e-0311902GO:0033313
GeneOntologyBiologicalProcesspostsynaptic membrane assembly

MAGI2 NRXN2

1.01e-0311902GO:0097104
GeneOntologyBiologicalProcessvitamin K metabolic process

CYP4F2 CYP4F12

1.01e-0311902GO:0042373
GeneOntologyBiologicalProcesslearned vocalization behavior or vocal learning

NEUROG1 NRXN2

1.01e-0311902GO:0098598
GeneOntologyBiologicalProcesssynaptic signaling

SNX14 NRXN2 NISCH RPS6KA3 PCLO APBA1 KCNQ2 SORBS1 GRIN2A MAPK1 ADNP CASK

1.07e-039769012GO:0099536
GeneOntologyCellularComponentsomatodendritic compartment

MAGI2 CACNA1S PALS1 SNX14 NEUROG1 CALCR PCLO APBA1 IGSF9 GRIN2A MAPK1 GNAS RET ADNP CNGA2 DICER1 CASK

2.61e-0512289317GO:0036477
GeneOntologyCellularComponentdendrite

MAGI2 CACNA1S SNX14 PCLO APBA1 IGSF9 GRIN2A MAPK1 GNAS RET ADNP DICER1 CASK

1.07e-048589313GO:0030425
GeneOntologyCellularComponentdendritic tree

MAGI2 CACNA1S SNX14 PCLO APBA1 IGSF9 GRIN2A MAPK1 GNAS RET ADNP DICER1 CASK

1.09e-048609313GO:0097447
GeneOntologyCellularComponentexoribonuclease complex

PNPT1 EXOSC10 PAN2

2.31e-0427933GO:1905354
MousePhenocoarse hair

IDS EDA PRLR

1.59e-059823MP:0002832
MousePhenodecreased pancreatic beta cell proliferation

PTTG3P PTTG1 PTTG2

3.10e-0511823MP:0011820
MousePhenodecreased pancreatic beta cell mass

PTTG3P PTTG1 PRLR PTTG2

3.49e-0532824MP:0009114
DomainPDZ

MAGI2 PALS1 IL16 PCLO APBA1 ARHGAP21 CASK

9.69e-06151927PS50106
DomainPDZ

MAGI2 PALS1 IL16 PCLO APBA1 ARHGAP21 CASK

1.01e-05152927IPR001478
DomainSecurin_separation-inh_met

PTTG1 PTTG2

2.40e-052922IPR018008
DomainSecurin_separation_inhibitor

PTTG1 PTTG2

2.40e-052922IPR006940
DomainSecurin

PTTG1 PTTG2

2.40e-052922PF04856
DomainGuanylate_kinase_CS

MAGI2 PALS1 CASK

6.18e-0516923IPR020590
DomainSH3_2

PALS1 SORBS1 MCF2L CASK RUSC2

6.61e-0586925PF07653
DomainSH3_2

PALS1 SORBS1 MCF2L CASK RUSC2

6.61e-0586925IPR011511
DomainPDZ

MAGI2 PALS1 IL16 APBA1 ARHGAP21 CASK

6.96e-05141926PF00595
DomainCyt_P450_E_grp-I

CYP4F8 CYP4F2 CYP4F3 CYP4F12

7.04e-0545924IPR002401
DomainHRDC

BLM EXOSC10

7.18e-053922SM00341
DomainHRDC

BLM EXOSC10

7.18e-053922PS50967
DomainHRDC

BLM EXOSC10

7.18e-053922PF00570
DomainPDZ

MAGI2 PALS1 IL16 APBA1 ARHGAP21 CASK

9.11e-05148926SM00228
DomainSH3

CASS4 PALS1 SH3PXD2A SORBS1 MCF2L CASK RUSC2

9.57e-05216927SM00326
DomainSH3

CASS4 PALS1 SH3PXD2A SORBS1 MCF2L CASK RUSC2

9.57e-05216927PS50002
Domain-

MAGI2 PALS1 IL16 APBA1 ARHGAP21 CASK

9.81e-051509262.30.42.10
DomainSH3_domain

CASS4 PALS1 SH3PXD2A SORBS1 MCF2L CASK RUSC2

1.07e-04220927IPR001452
DomainCyt_P450_CS

CYP4F8 CYP4F2 CYP4F3 CYP4F12

1.34e-0453924IPR017972
DomainHRDC_dom

BLM EXOSC10

1.43e-044922IPR002121
DomainGPCR_chapero_1

ANKRD13D ANKRD13C

1.43e-044922PF11904
DomainANKRD13

ANKRD13D ANKRD13C

1.43e-044922IPR021832
DomainCYTOCHROME_P450

CYP4F8 CYP4F2 CYP4F3 CYP4F12

1.78e-0457924PS00086
DomainGUANYLATE_KINASE_2

MAGI2 PALS1 CASK

1.91e-0423923PS50052
DomainGUANYLATE_KINASE_1

MAGI2 PALS1 CASK

1.91e-0423923PS00856
Domain-

CYP4F8 CYP4F2 CYP4F3 CYP4F12

1.91e-04589241.10.630.10
Domainp450

CYP4F8 CYP4F2 CYP4F3 CYP4F12

1.91e-0458924PF00067
DomainCyt_P450

CYP4F8 CYP4F2 CYP4F3 CYP4F12

2.18e-0460924IPR001128
DomainHRDC-like

BLM EXOSC10

2.38e-045922IPR010997
DomainGuanylate_kin

MAGI2 PALS1 CASK

2.77e-0426923PF00625
DomainGK/Ca_channel_bsu

MAGI2 PALS1 CASK

2.77e-0426923IPR008145
DomainGuanylate_kin-like_dom

MAGI2 PALS1 CASK

2.77e-0426923IPR008144
DomainGuKc

MAGI2 PALS1 CASK

2.77e-0426923SM00072
DomainRNaseH-like_dom

EXOSC10 POLE PAN2 PRPF8

3.73e-0469924IPR012337
DomainC2

SYT15 PCLO SYT14 PLA2G4A PLCB2

4.75e-04131925PF00168
DomainC2

SYT15 PCLO SYT14 PLA2G4A PLCB2

5.82e-04137925SM00239
DomainC2

SYT15 PCLO SYT14 PLA2G4A PLCB2

6.85e-04142925PS50004
DomainL27_C

PALS1 CASK

1.05e-0310922IPR014775
DomainL27

PALS1 CASK

1.05e-0310922PF02828
DomainC2_dom

SYT15 PCLO SYT14 PLA2G4A PLCB2

1.31e-03164925IPR000008
DomainPX

SNX14 SH3PXD2A NISCH

1.32e-0344923SM00312
DomainCoagulation_fac_subgr_Gla_dom

PRRG3 F10

1.53e-0312922IPR017857
Domain-

PRRG3 F10

1.53e-03129224.10.740.10
Domain-

EXOSC10 POLE PAN2

1.60e-03479233.30.420.10
DomainL27

PALS1 CASK

1.81e-0313922SM00569
DomainL27

PALS1 CASK

1.81e-0313922PS51022
DomainL27_dom

PALS1 CASK

1.81e-0313922IPR004172
DomainPX

SNX14 SH3PXD2A NISCH

1.81e-0349923PF00787
DomainPX

SNX14 SH3PXD2A NISCH

1.92e-0350923PS50195
Domain-

SNX14 SH3PXD2A NISCH

2.03e-03519233.30.1520.10
DomainGLA_1

PRRG3 F10

2.10e-0314922PS00011
DomainGLA_2

PRRG3 F10

2.10e-0314922PS50998
DomainGla

PRRG3 F10

2.10e-0314922PF00594
DomainGLA

PRRG3 F10

2.10e-0314922SM00069
DomainGLA_domain

PRRG3 F10

2.10e-0314922IPR000294
DomainPhox

SNX14 SH3PXD2A NISCH

2.15e-0352923IPR001683
PathwayREACTOME_EICOSANOIDS

CYP4F8 CYP4F2 CYP4F3 CYP4F12

3.94e-0712774M27129
PathwayREACTOME_EICOSANOIDS

CYP4F8 CYP4F2 CYP4F3 CYP4F12

3.94e-0712774MM14845
PathwayWP_EICOSANOID_METABOLISM_VIA_CYTOCHROME_P450_MONOOXYGENASES

CYP4F8 CYP4F2 CYP4F3 CYP4F12

7.90e-0714774MM15842
PathwayWP_EICOSANOID_METABOLISM_VIA_CYCLOOXYGENASES_COX

CYP4F8 PLA2G4A CYP4F2 CYP4F3 CYP4F12

8.98e-0733775MM15918
PathwayREACTOME_FATTY_ACIDS

CYP4F8 CYP4F2 CYP4F3 CYP4F12

1.07e-0615774M27126
PathwayREACTOME_MISCELLANEOUS_SUBSTRATES

CYP4F8 CYP4F2 CYP4F3 CYP4F12

2.38e-0618774MM14843
PathwayREACTOME_FATTY_ACIDS

CYP4F8 CYP4F2 CYP4F3 CYP4F12

2.38e-0618774MM14841
PathwayREACTOME_SYNTHESIS_OF_LEUKOTRIENES_LT_AND_EOXINS_EX

CYP4F8 CYP4F2 CYP4F3 CYP4F12

9.54e-0625774MM14858
PathwayREACTOME_ARACHIDONIC_ACID_METABOLISM

CYP4F8 PLA2G4A CYP4F2 CYP4F3 CYP4F12

2.00e-0561775MM14861
PathwayWP_EICOSANOID_METABOLISM_VIA_LIPOXYGENASES_LOX

CYP4F8 CYP4F2 CYP4F3 CYP4F12

2.99e-0533774MM15963
PathwayREACTOME_ACTIVATION_OF_NMDA_RECEPTORS_AND_POSTSYNAPTIC_EVENTS

RPS6KA3 APBA1 GRIN2A MAPK1 CASK

1.60e-0494775M2843
PathwayREACTOME_SYNTHESIS_OF_LEUKOTRIENES_LT_AND_EOXINS_EX

CYP4F8 CYP4F2 CYP4F3

1.94e-0421773M27137
PathwayKEGG_MELANOGENESIS

KITLG WNT10A PLCB2 MAPK1 GNAS

2.24e-04101775M7761
PathwayKEGG_GNRH_SIGNALING_PATHWAY

CACNA1S PLA2G4A PLCB2 MAPK1 GNAS

2.24e-04101775M1979
PathwayREACTOME_NEUREXINS_AND_NEUROLIGINS

NRXN2 APBA1 GRIN2A CASK

2.44e-0456774M27616
PathwayREACTOME_PHASE_I_FUNCTIONALIZATION_OF_COMPOUNDS

CYP4F8 CYP4F2 CYP4F3 CYP4F12 ADH1B

2.57e-04104775M738
PathwayREACTOME_PHASE_I_FUNCTIONALIZATION_OF_COMPOUNDS

CYP4F8 CYP4F2 CYP4F3 CYP4F12 ADH1B

2.69e-04105775MM14842
PathwayREACTOME_ARACHIDONIC_ACID_METABOLISM

CYP4F8 PLA2G4A CYP4F2 CYP4F3

2.98e-0459774M27140
PathwayWP_OXIDATION_BY_CYTOCHROME_P450

CYP4F8 CYP4F2 CYP4F3 CYP4F12

3.61e-0462774M39653
PathwayKEGG_OOCYTE_MEIOSIS

PTTG1 SMC1A RPS6KA3 MAPK1 PTTG2

3.78e-04113775M16817
PathwayREACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE

CYP4F8 CYP4F2 CYP4F3 CYP4F12

4.08e-0464774M5650
PathwayKEGG_VASCULAR_SMOOTH_MUSCLE_CONTRACTION

CACNA1S PLA2G4A PLCB2 MAPK1 GNAS

4.10e-04115775M9387
PathwayKEGG_MEDICUS_REFERENCE_ERK_RSK_SIGNALING

RPS6KA3 MAPK1

4.36e-046772M47936
PathwayREACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE

CYP4F8 CYP4F2 CYP4F3 CYP4F12

4.59e-0466774MM14839
PathwayKEGG_LONG_TERM_DEPRESSION

PLA2G4A PLCB2 MAPK1 GNAS

5.74e-0470774M8232
PathwayKEGG_LONG_TERM_POTENTIATION

RPS6KA3 PLCB2 GRIN2A MAPK1

5.74e-0470774M3115
PathwayREACTOME_RSK_ACTIVATION

RPS6KA3 MAPK1

6.08e-047772M27369
PathwayWP_EICOSANOID_METABOLISM_VIA_CYCLOOXYGENASES_COX

PLA2G4A CYP4F2 CYP4F12

6.31e-0431773M39851
PathwayWP_ALZHEIMERS_DISEASE

CACNA1S PLCB2 GRIN2A MAPK1

7.09e-0474774MM15962
PathwayWP_DISRUPTION_OF_POSTSYNAPTIC_SIGNALING_BY_CNV

NRXN2 GRIN2A MAPK1

7.60e-0433773M39875
PathwayREACTOME_G_ALPHA_12_13_SIGNALLING_EVENTS

RHOB ARHGEF33 MCF2L PLXNB1

8.23e-0477774MM15044
PathwayREACTOME_NEUROTRANSMITTER_RECEPTORS_AND_POSTSYNAPTIC_SIGNAL_TRANSMISSION

RPS6KA3 APBA1 PLCB2 GRIN2A MAPK1 CASK

8.84e-04205776M752
PathwayREACTOME_G_ALPHA_12_13_SIGNALLING_EVENTS

RHOB ARHGEF33 MCF2L PLXNB1

9.50e-0480774M800
PathwayWP_EICOSANOID_METABOLISM_VIA_CYTOCHROME_P450_MONOOXYGENASES_PATHWAY

CYP4F2 CYP4F12

1.03e-039772M39819
Pubmed

The cytochrome P450 4 (CYP4) family.

CYP4F8 CYP4F2 CYP4F3 CYP4F12

7.47e-1069449068972
Pubmed

Mice lacking pituitary tumor transforming gene show testicular and splenic hypoplasia, thymic hyperplasia, thrombocytopenia, aberrant cell cycle progression, and premature centromere division.

PTTG3P PTTG1 PTTG2

1.91e-08394311682618
Pubmed

Pituitary Tumor Transforming Gene 1 Orchestrates Gene Regulatory Variation in Mouse Ventral Midbrain During Aging.

PTTG3P PTTG1 PTTG2

1.91e-08394333173537
Pubmed

PTTG1 Reprograms Asparagine Metabolism to Promote Hepatocellular Carcinoma Progression.

PTTG3P PTTG1 PTTG2

1.91e-08394337159932
Pubmed

Mad2 is required for inhibiting securin and cyclin B degradation following spindle depolymerisation in meiosis I mouse oocytes.

PTTG3P PTTG1 PTTG2

1.91e-08394316322543
Pubmed

PTTG1 alleviates acute alcoholic liver injury by inhibiting endoplasmic reticulum stress-induced hepatocyte pyroptosis.

PTTG3P PTTG1 PTTG2

1.91e-08394336737842
Pubmed

Pituitary senescence: the evolving role of Pttg.

PTTG3P PTTG1 PTTG2

1.91e-08394320153804
Pubmed

Pituitary tumor transforming gene (PTTG) transforming and transactivation activity.

PTTG3P PTTG1 PTTG2

1.91e-08394310713046
Pubmed

Sex-steroid milieu determines diabetes rescue in pttg-null mice.

PTTG3P PTTG1 PTTG2

1.91e-08394316731783
Pubmed

Mechanisms for growth factor-induced pituitary tumor transforming gene-1 expression in pituitary folliculostellate TtT/GF cells.

PTTG3P PTTG1 PTTG2

1.91e-08394316959877
Pubmed

Regulation of pituitary tumor transforming gene (PTTG) expression and phosphorylation in thyroid cells.

PTTG3P PTTG1 PTTG2

1.91e-08394323867215
Pubmed

Characterization of the pituitary tumor transforming gene 1 knockout mouse retina.

PTTG3P PTTG1 PTTG2

1.91e-08394321203837
Pubmed

PTTG is a secretory protein in human pituitary adenomas and in mouse pituitary tumor cell lines.

PTTG3P PTTG1 PTTG2

1.91e-08394317652795
Pubmed

Pttg1/securin is required for the branching morphogenesis of the mammary gland and suppresses mammary tumorigenesis.

PTTG3P PTTG1 PTTG2

1.91e-08394324395789
Pubmed

The lifespan quantitative trait locus gene Securin controls hematopoietic progenitor cell function.

PTTG3P PTTG1 PTTG2

1.91e-08394331073078
Pubmed

A prometaphase mechanism of securin destruction is essential for meiotic progression in mouse oocytes.

PTTG3P PTTG1 PTTG2

1.91e-08394334262048
Pubmed

Pituitary tumor transforming gene as a novel regulatory factor of liver fibrosis.

PTTG3P PTTG1 PTTG2

1.91e-08394325936962
Pubmed

Discordant proliferation and differentiation in pituitary tumor-transforming gene-null bone marrow stem cells.

PTTG3P PTTG1 PTTG2

1.91e-08394317626243
Pubmed

Pituitary tumor transforming gene: an update.

PTTG3P PTTG1 PTTG2

1.91e-08394315281346
Pubmed

Securin and not CDK1/cyclin B1 regulates sister chromatid disjunction during meiosis II in mouse eggs.

PTTG3P PTTG1 PTTG2

1.91e-08394318639540
Pubmed

Pituitary tumor transforming gene-null male mice exhibit impaired pancreatic beta cell proliferation and diabetes.

PTTG3P PTTG1 PTTG2

1.91e-08394312626748
Pubmed

Maternal age-dependent APC/C-mediated decrease in securin causes premature sister chromatid separation in meiosis II.

PTTG3P PTTG1 PTTG2

1.91e-08394328516917
Pubmed

Characterization of the murine pituitary tumor transforming gene (PTTG) and its promoter.

PTTG3P PTTG1 PTTG2

1.91e-08394310650958
Pubmed

Murine pituitary tumor-transforming gene functions as a securin protein in insulin-secreting cells.

PTTG3P PTTG1 PTTG2

1.91e-08394317065388
Pubmed

Anaphase B precedes anaphase A in the mouse egg.

PTTG3P PTTG1 PTTG2

7.63e-08494322342753
Pubmed

Securin and separase phosphorylation act redundantly to maintain sister chromatid cohesion in mammalian cells.

PTTG3P PTTG1 PTTG2

7.63e-08494316030258
Pubmed

Degradation of securin in mouse and pig oocytes is dependent on ubiquitin-proteasome pathway and is required for proteolysis of the cohesion subunit, Rec8, at the metaphase-to-anaphase transition.

PTTG3P PTTG1 PTTG2

7.63e-08494316720305
Pubmed

The pituitary tumor-transforming gene promotes angiogenesis in a mouse model of follicular thyroid cancer.

PTTG3P PTTG1 PTTG2

7.63e-08494317127711
Pubmed

Tumor suppressor activity of KLF6 mediated by downregulation of the PTTG1 oncogene.

PTTG3P PTTG1 PTTG2

7.63e-08494320116377
Pubmed

Disruption of mouse cytochrome p450 4f14 (Cyp4f14 gene) causes severe perturbations in vitamin E metabolism.

CYP4F8 CYP4F2 CYP4F12

7.63e-08494322665481
Pubmed

Pituitary tumor transforming gene 1 induces tumor necrosis factor-α production from keratinocytes: implication for involvement in the pathophysiology of psoriasis.

PTTG3P PTTG1 PTTG2

7.63e-08494323677169
Pubmed

Expression and catalytic activity of mouse leukotriene B4 omega-hydroxylase, CYP4F14.

CYP4F8 CYP4F2 CYP4F12

7.63e-08494311185557
Pubmed

Preimplantation mouse embryos depend on inhibitory phosphorylation of separase to prevent chromosome missegregation.

PTTG3P PTTG1 PTTG2

7.63e-08494319124608
Pubmed

Induction of Dlk1 by PTTG1 inhibits adipocyte differentiation and correlates with malignant transformation.

PTTG3P PTTG1 PTTG2

7.63e-08494319477929
Pubmed

The pituitary tumour-transforming gene 1/delta-like homologue 1 pathway plays a key role in liver fibrogenesis.

PTTG3P PTTG1 PTTG2

7.63e-08494335050550
Pubmed

Spatial learning and long-term memory impairments in RasGrf1 KO, Pttg1 KO, and double KO mice.

PTTG3P PTTG1 PTTG2

7.63e-08494330259712
Pubmed

Expression of PTTG and prc1 genes during telencephalic neurogenesis.

PTTG3P PTTG1 PTTG2

7.63e-08494310727870
Pubmed

Pituitary tumor-transforming gene 1 regulates the patterning of retinal mosaics.

PTTG3P PTTG1 PTTG2

7.63e-08494324927528
Pubmed

Glypican-1 regulates anaphase promoting complex/cyclosome substrates and cell cycle progression in endothelial cells.

PTTG3P PTTG1 PTTG2

7.63e-08494318417614
Pubmed

Pituitary hypoplasia in Pttg-/- mice is protective for Rb+/- pituitary tumorigenesis.

PTTG3P PTTG1 PTTG2

7.63e-08494315919720
Pubmed

Securin is not required for cellular viability, but is required for normal growth of mouse embryonic fibroblasts.

PTTG3P PTTG1 PTTG2

7.63e-08494311516952
Pubmed

Tumorigenic potential of pituitary tumor transforming gene (PTTG) in vivo investigated using a transgenic mouse model, and effects of cross breeding with p53 (+/-) transgenic mice.

PTTG3P PTTG1 PTTG2

7.63e-08494323164239
Pubmed

Abnormal megakaryocyte development and platelet function in Nbeal2(-/-) mice.

PTTG3P PTTG1 PTTG2

7.63e-08494323861251
Pubmed

Omega oxidation of 3-hydroxy fatty acids by the human CYP4F gene subfamily enzyme CYP4F11.

CYP4F2 CYP4F3 CYP4F12

7.63e-08494318065749
Pubmed

The selective continued linkage of centromeres from mitosis to interphase in the absence of mammalian separase.

PTTG3P PTTG1 PTTG2

7.63e-08494316533944
Pubmed

Separase: a universal trigger for sister chromatid disjunction but not chromosome cycle progression.

PTTG3P PTTG1 PTTG2

7.63e-08494316533945
Pubmed

Aberrant accumulation of PTTG1 induced by a mutated thyroid hormone beta receptor inhibits mitotic progression.

PTTG3P PTTG1 PTTG2

7.63e-08494317039256
Pubmed

Transcriptional profiling reveals functional links between RasGrf1 and Pttg1 in pancreatic beta cells.

PTTG3P PTTG1 PTTG2

7.63e-08494325421944
Pubmed

A single amino acid substitution (Cys249Trp) in Crb1 causes retinal degeneration and deregulates expression of pituitary tumor transforming gene Pttg1.

PTTG3P PTTG1 PTTG2

7.63e-08494317234588
Pubmed

Homologue disjunction in mouse oocytes requires proteolysis of securin and cyclin B1.

PTTG3P PTTG1 PTTG2

7.63e-08494314593421
Pubmed

Securin regulates entry into M-phase by modulating the stability of cyclin B.

PTTG3P PTTG1 PTTG2

7.63e-08494318364698
Pubmed

A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse.

SNX14 KCNQ2 SORBS1 CHGB MCF2L CASK

1.22e-078594623055939
Pubmed

Disruption of P450-mediated vitamin E hydroxylase activities alters vitamin E status in tocopherol supplemented mice and reveals extra-hepatic vitamin E metabolism.

CYP4F8 CYP4F2 CYP4F12

1.90e-07594322969154
Pubmed

p21(Cip1) restrains pituitary tumor growth.

PTTG3P PTTG1 PTTG2

1.90e-07594318981426
Pubmed

MEIKIN expression and its C-terminal phosphorylation by PLK1 is closely related the metaphase-anaphase transition by affecting cyclin B1 and Securin stabilization in meiotic oocyte.

PTTG3P PTTG1 PTTG2

1.90e-07594339093409
Pubmed

PTTG-binding factor (PBF) is a novel regulator of the thyroid hormone transporter MCT8.

PTTG3P PTTG1 PTTG2

1.90e-07594322535767
Pubmed

Cytochrome P4504f, a potential therapeutic target limiting neuroinflammation.

CYP4F8 CYP4F2 CYP4F12

1.90e-07594321466787
Pubmed

Smurf1 targets Securin for ubiquitin-dependent degradation and regulates the metaphase-to-anaphase transition.

PTTG3P PTTG1 PTTG2

1.90e-07594328658604
Pubmed

The meiosis I-to-meiosis II transition in mouse oocytes requires separase activity.

PTTG3P PTTG1 PTTG2

1.90e-07594314561405
Pubmed

The Rae1-Nup98 complex prevents aneuploidy by inhibiting securin degradation.

PTTG3P PTTG1 PTTG2

1.90e-07594316355229
Pubmed

Altered expression of securin (Pttg1) and serpina3n in the auditory system of hearing-impaired Tff3-deficient mice.

PTTG3P PTTG1 PTTG2

1.90e-07594321076990
Pubmed

Targeting mitotic exit leads to tumor regression in vivo: Modulation by Cdk1, Mastl, and the PP2A/B55α,δ phosphatase.

PTTG3P PTTG1 PTTG2

1.90e-07594321156286
Pubmed

Senescence mediates pituitary hypoplasia and restrains pituitary tumor growth.

PTTG3P PTTG1 PTTG2

1.90e-07594317975001
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

PIK3R4 MAGI2 PPP4R3B PCYT1A PDHB SMC1A NISCH APBA1 KCNQ2 SORBS1 PJA1 IDS PRPF8 NSUN2 ARHGAP21 CASK

3.35e-071285941635914814
Pubmed

Involvement of histone deacetylase 1/2 in adrenocorticotropic hormone synthesis and proliferation of corticotroph tumor AtT-20 cells.

PTTG3P PTTG1 PTTG2

3.80e-07694333181265
Pubmed

mTOR promotes pituitary tumor development through activation of PTTG1.

PTTG3P PTTG1 PTTG2

3.80e-07694327524416
Pubmed

Function of COP9 signalosome in regulation of mouse oocytes meiosis by regulating MPF activity and securing degradation.

PTTG3P PTTG1 PTTG2

3.80e-07694321991377
Pubmed

SALM4 suppresses excitatory synapse development by cis-inhibiting trans-synaptic SALM3-LAR adhesion.

MAGI2 GRIN2A MAPK1 CASK

6.06e-072594427480238
Pubmed

Role of ω-hydroxylase in adenosine-mediated aortic response through MAP kinase using A2A-receptor knockout mice.

CYP4F8 CYP4F2 CYP4F12

6.64e-07794322160543
Pubmed

Loss of Cdc20 causes a securin-dependent metaphase arrest in two-cell mouse embryos.

PTTG3P PTTG1 PTTG2

6.64e-07794317325031
Pubmed

Identification of disease-relevant modulators of the SHH pathway in the developing brain.

PTTG3P PTTG1 PTTG2

1.59e-06994334463328
Pubmed

Defective transcription initiation causes postnatal growth failure in a mouse model of nucleotide excision repair (NER) progeria.

GTF2B CYP4F8 CYP4F2 CYP4F12 PRLR

2.06e-067694522323595
Pubmed

Cdk5 promotes synaptogenesis by regulating the subcellular distribution of the MAGUK family member CASK.

APBA1 GRIN2A CASK

2.26e-061094318054859
Pubmed

Nuclear pore protein NUP88 activates anaphase-promoting complex to promote aneuploidy.

PTTG3P PTTG1 PTTG2

2.26e-061094326731471
Pubmed

Separase phosphosite mutation leads to genome instability and primordial germ cell depletion during oogenesis.

PTTG3P PTTG1 PTTG2

3.11e-061194321494564
Pubmed

Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.

BLM PPP4R3B PCYT1A GTF2B EXOSC10 POLE SMC1A MAPK1 PAF1 PRPF8 ADNP NSUN2 UBE2E3

3.46e-061014941332416067
Pubmed

MYC Protein Interactome Profiling Reveals Functionally Distinct Regions that Cooperate to Drive Tumorigenesis.

BLM YEATS2 EXOSC10 PAF1 PRPF8 ADNP NSUN2 KNL1

4.03e-0633994830415952
Pubmed

Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.

PIK3R4 BLM PCF11 EXOSC10 POLE SMC1A GNAS PRPF8 KNL1 HDLBP

4.09e-06582941020467437
Pubmed

Diminished pancreatic beta-cell mass in securin-null mice is caused by beta-cell apoptosis and senescence.

PTTG3P PTTG1 PTTG2

5.36e-061394319213844
Pubmed

Specificity and Redundancy of Profilin 1 and 2 Function in Brain Development and Neuronal Structure.

PTTG3P PTTG1 PTTG2

5.36e-061394334571959
Pubmed

Stretch-induced ERK2 phosphorylation requires PLA2 activity in skeletal myotubes.

PLA2G4A MAPK1

7.23e-06294219524551
Pubmed

cPLA2 is phosphorylated and activated by MAP kinase.

PLA2G4A MAPK1

7.23e-0629428381049
Pubmed

Gene signatures and prognostic analyses of the Tob/BTG pituitary tumor-transforming gene (PTTG) family in clinical breast cancer patients.

PTTG3P PTTG1

7.23e-06294233173433
Pubmed

Testing the Ret and Sema3d genetic interaction in mouse enteric nervous system development.

SEMA3D RET

7.23e-06294228334784
Pubmed

The lncRNA PTTG3P promotes the progression of CRPC via upregulating PTTG1.

PTTG3P PTTG1

7.23e-06294233743960
Pubmed

Involvement of and interaction between WNT10A and EDA mutations in tooth agenesis cases in the Chinese population.

WNT10A EDA

7.23e-06294224312213
Pubmed

Mapping of the gene encoding the alpha subunit of the stimulatory G protein of adenylyl cyclase (GNAS1) to 20q13.2----q13.3 in human by in situ hybridization.

CHGB GNAS

7.23e-0629421769666
Pubmed

Expression of CYP4F2 in human liver and kidney: assessment using targeted peptide antibodies.

CYP4F2 CYP4F12

7.23e-06294218662666
Pubmed

Expression and physiological function of CYP4F subfamily in human eosinophils.

CYP4F3 CYP4F12

7.23e-06294217980168
Pubmed

Molecular analysis of the X11-mLin-2/CASK complex in brain.

APBA1 CASK

7.23e-0629429952408
Pubmed

Cloning and expression of a novel form of leukotriene B4 omega-hydroxylase from human liver.

CYP4F2 CYP4F3

7.23e-0629428026587
Pubmed

Identification of the human pituitary tumor transforming gene (hPTTG) family: molecular structure, expression, and chromosomal localization.

PTTG3P PTTG2

7.23e-06294210806349
Pubmed

Oxygenation of polyunsaturated long chain fatty acids by recombinant CYP4F8 and CYP4F12 and catalytic importance of Tyr-125 and Gly-328 of CYP4F8.

CYP4F8 CYP4F12

7.23e-06294216112640
Pubmed

A non-catalytic herpesviral protein reconfigures ERK-RSK signaling by targeting kinase docking systems in the host.

RPS6KA3 MAPK1

7.23e-06294235078976
Pubmed

The long non-coding RNA PTTG3P promotes cell growth and metastasis via up-regulating PTTG1 and activating PI3K/AKT signaling in hepatocellular carcinoma.

PTTG3P PTTG1

7.23e-06294229803224
Pubmed

TAF4, a subunit of transcription factor II D, directs promoter occupancy of nuclear receptor HNF4A during post-natal hepatocyte differentiation.

GTF2B CYP4F8 CYP4F2 CYP4F12

7.48e-064694425209997
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

BLM PCF11 YEATS2 PTTG1 AFTPH SMC1A RALGAPB PLA2G4A NSUN2 UBE2E3 HDLBP

7.98e-06774941115302935
Pubmed

TIF1β association with HP1 is essential for post-gastrulation development, but not for Sertoli cell functions during spermatogenesis.

PTTG3P PTTG1 PTTG2

8.50e-061594321163256
Pubmed

A systematic, genome-wide, phenotype-driven mutagenesis programme for gene function studies in the mouse.

CELSR1 KITLG EDA

1.04e-051694310932191
Pubmed

Inhibitory phosphorylation of separase is essential for genome stability and viability of murine embryonic germ cells.

PTTG3P PTTG1 PTTG2

1.04e-051694318232736
InteractionTNIK interactions

RHOB MAGI2 PALS1 KCNQ2 GRIN2A MAPK1 PAF1 ADNP ARHGAP21 CASK HDLBP

1.30e-063819211int:TNIK
InteractionDUSP2 interactions

POLE SMC1A MAPK1 PRPF8 DICER1 UBE2E3

1.89e-0681926int:DUSP2
InteractionDUSP26 interactions

POLE SMC1A RET PRPF8 DICER1

7.32e-0659925int:DUSP26
InteractionPTGDR interactions

ANKRD13C MAPK1 GNAS

1.97e-0512923int:PTGDR
InteractionRAP1B interactions

RHOB PDHB DERL2 APLP1 CHGB DICER1 HDLBP

2.23e-05185927int:RAP1B
InteractionCPA6 interactions

CPA6 PJA1 DICER1

4.03e-0515923int:CPA6
InteractionARHGEF26 interactions

RHOB APBA1 MAPK1 CASK

4.80e-0544924int:ARHGEF26
GeneFamilyPDZ domain containing

MAGI2 PALS1 IL16 PCLO APBA1 ARHGAP21 CASK

1.80e-061526971220
GeneFamilyCytochrome P450 family 4

CYP4F8 CYP4F2 CYP4F3 CYP4F12

1.04e-05366941003
GeneFamilyCalcium voltage-gated channel subunits|Membrane associated guanylate kinases

MAGI2 PALS1 CASK

1.30e-0426693904
GeneFamilyGranins

CHGB GNAS

3.96e-048692925
GeneFamilySynaptotagmins

SYT15 SYT14

1.88e-0317692765
GeneFamilyPhospholipases|C2 domain containing phospholipases

PLA2G4A PLCB2

2.35e-0319692832
CoexpressionGUO_HEX_TARGETS_DN

PTTG3P PTTG1 F10 SLC39A8 PTTG2

5.36e-0670945MM629
CoexpressionGSE43955_10H_VS_30H_ACT_CD4_TCELL_WITH_TGFB_IL6_DN

NEUROG1 SPSB1 KCNQ2 SORBS1 RET CASK HDLBP

7.66e-06199947M9697
CoexpressionGSE9960_HEALTHY_VS_GRAM_NEG_SEPSIS_PBMC_UP

HEXA RHOB CELSR1 SH3PXD2A PLCB2 GNAS HDLBP

7.66e-06199947M7118
CoexpressionKIM_ALL_DISORDERS_CALB1_CORR_UP

CLIP3 PDHB TOGARAM1 APLP1 GRIN2A MAPK1 CHGB GNAS PRPF8 UBE2E3

2.72e-055479410M2110
CoexpressionLIANG_HEMATOPOIESIS_STEM_CELL_NUMBER_QTL

PTTG3P PTTG1 PTTG2

4.15e-0519943MM848
CoexpressionSMID_BREAST_CANCER_BASAL_DN

RHOB CYP4F8 CELSR1 PCLO PAN2 RET MCF2L WIPF2 PRLR PLXNB1 ADH1B

4.16e-056999411M4960
CoexpressionSAENZ_DETOX_PATHWAY_AND_CARCINOGENESIS_DN

CYP4F8 CYP4F2 CYP4F12

4.87e-0520943MM1104
CoexpressionMIKKELSEN_MEF_HCP_WITH_H3K27ME3

CELSR1 NEUROG1 CALCR NRXN2 WNT10A KCNQ2 GRIN2A CHGB MCF2L PRLR

5.21e-055919410M2019
CoexpressionMIKKELSEN_MEF_HCP_WITH_H3K27ME3

CELSR1 NEUROG1 CALCR NRXN2 WNT10A KCNQ2 GRIN2A CHGB MCF2L PRLR

5.99e-056019410MM866
CoexpressionGSE2770_IL12_ACT_VS_ACT_CD4_TCELL_2H_UP

IL16 RET PJA1 ADNP UBE2E3 PRLR

7.01e-05193946M6130
CoexpressionGSE2405_0H_VS_3H_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_DN

CASS4 CELSR1 CYP4F3 EDA CNGA2 ADH1B

8.08e-05198946M6213
CoexpressionGSE15659_RESTING_TREG_VS_NONSUPPRESSIVE_TCELL_DN

PNPT1 SMC1A SYT14 PKD2L1 PLCB2 TTC33

8.30e-05199946M3560
CoexpressionGABRIELY_MIR21_TARGETS

PALS1 SMC1A RPS6KA3 ADNP ARHGAP21 KNL1 TTC33

8.32e-05289947M2196
CoexpressionGSE1925_3H_VS_24H_IFNG_STIM_IFNG_PRIMED_MACROPHAGE_UP

PTTG1 CELSR1 SPSB1 CAPN3 DICER1 SLC39A8

8.54e-05200946M6300
CoexpressionGSE37534_GW1929_VS_PIOGLITAZONE_TREATED_CD4_TCELL_PPARG1_FOXP3_TRANSDUCED_DN

MAGI2 RPS6KA3 RALGAPB PAN2 MAPK1 UBE2E3

8.54e-05200946M8986
CoexpressionGSE17721_POLYIC_VS_GARDIQUIMOD_6H_BMDC_UP

PNPT1 PTTG1 SPSB1 IGSF9 PLCB2 PRLR

8.54e-05200946M4024
CoexpressionGSE17721_12H_VS_24H_POLYIC_BMDC_UP

RHOB PNPT1 PLA2G4A IGSF9 IDS CASK

8.54e-05200946M4101
CoexpressionGSE17721_POLYIC_VS_CPG_2H_BMDC_DN

PALS1 CAPN3 IGSF9 APLP1 ARHGAP21 HDLBP

8.54e-05200946M3939
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HDA

MAGI2 SEMA3D NRXN2 SH3PXD2A IGSF9 APLP1 CLUL1 PRLR SLC39A8

8.63e-05506949M39067
CoexpressionMCBRYAN_PUBERTAL_TGFB1_TARGETS_DN

PTTG3P PTTG1 KITLG PTTG2

1.19e-0470944MM994
CoexpressionVIETOR_IFRD1_TARGETS

PTTG3P PTTG1 PTTG2

1.23e-0427943MM655
CoexpressionPUJANA_ATM_PCC_NETWORK

BLM PCF11 HEXA PCYT1A SEMA3D GTF2B EXOSC10 IL16 POLE SMC1A RALGAPB APBA1 IDS ADNP PTTG2

1.26e-0413949415M9585
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HGABA

MAGI2 NRXN2 SH3PXD2A PCLO APBA1 APLP1 SORBS1 MCF2L IDS DICER1 PRLR CASK RUSC2

1.58e-0411069413M39071
CoexpressionWOO_LIVER_CANCER_RECURRENCE_DN

CYP4F2 CYP4F3 CYP4F12 ADH1B

1.81e-0478944M9911
CoexpressionKAUFFMANN_DNA_REPLICATION_GENES

BLM PTTG3P PTTG1 SMC1A PTTG2

1.85e-04146945M9372
CoexpressionHE_LIM_SUN_FETAL_LUNG_C1_PULMONARY_NEUROENDOCRINE_CELL

CLIP3 PKD2L1 APLP1 CHGB RET FREM1

1.96e-04233946M45712
CoexpressionAtlasDevelopingGonad_e16.5_epididymis_emap-29702_k-means-cluster#1_top-relative-expression-ranked_1000

PALS1 CLIP3 SMC1A NISCH APLP1 CASK

1.56e-05124916gudmap_developingGonad_e16.5_epididymis_1000_k1
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_A_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GTF2B CALCR ADAMTS18 KCNQ2 APLP1 CHGB GNAS

1.39e-0718694716092819e9148dfe64f07c737652b6e533e699f7
ToppCelldroplet-Pancreas-Endocrine-18m-Epithelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HEXA NISCH PCLO APLP1 CHGB GNAS PRLR

1.67e-07191947fd01a206763dfb6d52cca67123571936b4a8e1a0
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SH3PXD2A NISCH PCLO APLP1 CHGB PRLR HDLBP

1.79e-07193947fe451b3295d77b2bd1ac25cf29310c85835a45fe
ToppCellTracheal-10x3prime_v2-Epithelial-Epi_airway_neuro-secretory|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

BLM PCLO APLP1 CYP4F3 CHGB RET DCAF4

2.06e-07197947ff4df77117165b6b25315e29b0722cc136eba607
ToppCellfacs-Marrow-B-cells-24m-Hematologic-Unknown_Progenitor|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1S ARHGEF33 ADAMTS18 WNT10A PKD2L1 PRLR

1.76e-0617294665b8935a972bf00b7a10dc2d442128fc0ed78bcb
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_A_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CALCR ADAMTS18 KCNQ2 APLP1 CHGB GNAS

2.69e-061859464e40d3103ebf4a7066b7ce300b6ef700ba0e2863
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CLIP3 APBA1 WNT10A RET DCAF4 ADH1B

2.69e-06185946e1fbec55b71f604189eb2431768fadbaa0453a83
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CLIP3 APBA1 WNT10A RET DCAF4 ADH1B

2.69e-061859469d933cd5ebc8368fd37aa83113d2dfa6938ff72d
ToppCellwk_15-18-Epithelial-Proximal_epithelial-Pulmonary_neuroendocrine|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

SYT14 PKD2L1 APLP1 CHGB RET MCF2L

2.77e-06186946fcabebdfbf1b1dbb35ce2b3c53a60d2b1aed8e6c
ToppCell11.5-Airway-Epithelial-Neuroendocrine|Airway / Age, Tissue, Lineage and Cell class

PCLO PKD2L1 APLP1 CHGB RET MCF2L

3.23e-06191946c1bb3ae5c297f55cdadf5b6e53d5296389d5099e
ToppCelldroplet-Pancreas-Endocrine-18m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SH3PXD2A NISCH PCLO APLP1 CHGB PRLR

3.33e-061929461304e69c92cef3bd8c82e3c035a7562f5440139a
ToppCelldroplet-Pancreas-Endocrine|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HEXA NISCH APLP1 CHGB GNAS PRLR

3.33e-061929460dfd1e9896c34aee0f842f8de5d0e3af62a15f68
ToppCelldroplet-Pancreas-Endocrine-18m|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HEXA PCLO APLP1 CHGB GNAS PRLR

3.33e-061929464510aa262da8dcf7c944b3907a51aba5a9397a4e
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SH3PXD2A NISCH PCLO CHGB PRLR HDLBP

3.43e-06193946471e65f02937bc18d7c5facdacdf1df58cf0f839
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

CASS4 MAGI2 IL16 KITLG FREM1 ADH1B

3.43e-0619394699525545552b371c86b18b6ea6f4897dc6e9a9ec
ToppCelldroplet-Pancreas-Endocrine-21m|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SH3PXD2A NISCH APLP1 CHGB PRLR HDLBP

3.53e-061949463a3ecedcdc7691cf21775818b598208fcb980c29
ToppCelldroplet-Pancreas-Endocrine-18m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SH3PXD2A NISCH PCLO APLP1 CHGB PRLR

3.53e-0619494692b39a935e8c577eb1123d706d168fa13cf3344c
ToppCellTCGA-Adrenal-Primary_Tumor-Pheochromocytoma|TCGA-Adrenal / Sample_Type by Project: Shred V9

CLIP3 APBA1 KCNQ2 APLP1 CHGB MCF2L

3.53e-06194946b6488bc3a8905e926ad298332963e1bbaf010046
ToppCellTCGA-Adrenal-Primary_Tumor-Pheochromocytoma-Pheochromocytoma|TCGA-Adrenal / Sample_Type by Project: Shred V9

CLIP3 APBA1 KCNQ2 APLP1 CHGB MCF2L

3.53e-061949461e1f4139ad584f493d75a9b7f1568eca4653c5a2
ToppCell3'-GW_trimst-1-SmallIntestine-Neuronal|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NRXN2 SYT14 KCNQ2 APLP1 CHGB RET

4.09e-0619994686739a6f5e0fa7448389b97b3c4de41f2a7d7ebd
ToppCellBiopsy_Other_PF-Epithelial-KRT5-/KRT17+|Biopsy_Other_PF / Sample group, Lineage and Cell type

CPA6 CELSR1 SYT14 WNT10A IGSF9 PLXNB1

4.21e-06200946077e6b9340686de9d0f11b035a8954e1f6a1b790
ToppCellControl-Epithelial-Ionocyte|Epithelial / Disease state, Lineage and Cell class

PKD2L1 RET PJA1 F10 FREM1

1.95e-051559454b9369b203a4d7071c56d3d8e6b450e9a0121c41
ToppCellPND14-Immune-Immune_Myeloid-DC-cDC2-cDC2_prolif|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

POLE SYT14 PLA2G4A IGSF9 KNL1

2.01e-051569458349604bd801e20d33770f7d8243598c3756302b
ToppCellfacs-Marrow-T-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGEF33 SPSB1 PKD2L1 GRIN2A CNGA2

2.14e-05158945f296ca24fdedc33f1d24b79e7660763114ce7fa3
ToppCellfacs-Marrow-T-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGEF33 SPSB1 PKD2L1 GRIN2A CNGA2

2.14e-051589458c7108f2c40d97a317762ba0b8eca76542b2ebaf
ToppCell368C-Myeloid-Macrophage-SPP1+_Macrophage_2|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

PIK3R4 KITLG ANKRD13C POLE APBA1

2.95e-05169945c6e5b179461996ced6c7621dc01cec00d401f4e8
ToppCellfacs-Marrow-B-cells-24m-Hematologic-hematopoietic_stem_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1S ARHGEF33 WNT10A PKD2L1 PRLR

3.21e-05172945a7fd4d61fb5017dce001d69d6b9a01e6cdf58828
ToppCelldroplet-Marrow-nan-24m-Lymphocytic-late_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1S WNT10A PKD2L1 APLP1 PRLR

3.39e-05174945cdfc50e5383c8670ce5109736aff36406f46c03d
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-enteroendocrine_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAGI2 PCLO APBA1 CHGB RET

3.78e-0517894530ca37f70d267cc9b40ca3e211f16d30360c3e6b
ToppCellTCGA-Adrenal-Primary_Tumor-Pheochromocytoma-Pheochromocytoma-1|TCGA-Adrenal / Sample_Type by Project: Shred V9

PCLO SORBS1 CHGB RET IDS

3.89e-05179945431e1b29015ec817f778499106d24b19cfc825ae
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

CASS4 IL16 KITLG FREM1 ADH1B

4.10e-051819459ede19228ba5c0668a9c06c915510b95585216ef
ToppCelldroplet-Limb_Muscle-Pre-Sort-18m-Macroglial-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA3D CELSR1 IGSF9 SORBS1 PLXNB1

4.20e-05182945c00e503f442d44fbae73c5e2dc85be69e294e67a
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PCLO CYP4F2 CYP4F3 MCF2L PRLR

4.32e-05183945facd6dbe0851b537d70a899ac7485714ab27d071
ToppCelldroplet-Thymus-nan-18m-Myeloid-Plasma_cells_and_B_cells|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RHOB CACNA1S WNT10A IGSF9 PRLR

4.32e-05183945ffb1bbbccb34d1a7e99872611f497450039d5019
ToppCell18-Distal-Epithelial-Neuroendocrine|Distal / Age, Tissue, Lineage and Cell class

PCLO SYT14 PKD2L1 APLP1 CHGB

4.54e-05185945f8fc7b12b4e18d23d84e95488be93c4352d325f3
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRXN2 PCLO KCNQ2 GRIN2A CHGB

4.78e-05187945e04a84989d624378141042768383b9c846901f2d
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRXN2 PCLO KCNQ2 GRIN2A CHGB

4.78e-0518794524cc03c748e15f7ef0e6509ca5a6ca583fb9c573
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRXN2 PCLO KCNQ2 GRIN2A CHGB

4.78e-051879452f153b203fe79f206319603cf94d3a03ab49a05d
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-A|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SPSB1 CAPN3 ADAMTS18 APLP1 ARHGAP21

4.91e-051889456c7ce6e28e4433092605880acf127833e7b66ebe
ToppCellfacs-MAT-Fat-3m|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA3D IDS PRPF8 PRLR RUSC2

4.91e-051889457da9750255efbc5cf9aed7e3105a337fac63b9f0
ToppCellControl-Fibroblasts-Adventitial_FB|Control / group, cell type (main and fine annotations)

SEMA3D IL16 SPSB1 FREM1 ADH1B

4.91e-05188945706a26c372add839d947749f0521a0e1f5c9b0ec
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c13-MKI67-CCL5_l|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CLIP3 PTTG1 SPSB1 NSUN2 KNL1

4.91e-0518894515146fd2c5592ea84d20b1fdd172b39cd60b5bed
ToppCellfacs-Pancreas-Endocrine-24m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SH3PXD2A NISCH PCLO APLP1 PRLR

4.91e-05188945a91443aa8fa8fa87f7501c59219daa0305bd0bbf
ToppCellhuman_hepatoblastoma-Tumor_cells-T5|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

CPA6 KITLG ADAMTS18 GRIN2A FREM1

4.91e-05188945b070a0667f1ee9b825b267b6c389b7c42fc436f9
ToppCelldroplet-Spleen-nan-24m-Lymphocytic-plasma_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RHOB CACNA1S WNT10A PRLR HDLBP

5.16e-05190945992539c380576bf810c00a5f926cf1ee7d57dcf5
ToppCellwk_08-11-Epithelial-PNS-Schwann_precursor|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

RHOB NEUROG1 NRXN2 KCNQ2 RET

5.16e-051909454a777d8aa19cadd3b61b023772df142421a89113
ToppCellcellseq-Epithelial-Epithelial_Neuro-Secretory-PNEC-PNEC|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SYT14 ADAMTS18 APLP1 CHGB RET

5.29e-05191945146cfd4daa2878536b4f381564c787919ad855a8
ToppCellfacs-Pancreas-Endocrine-24m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SH3PXD2A PCLO APLP1 CHGB PRLR

5.29e-051919453387b95a3f2445c672d407922fdce3a91eabaef8
ToppCellcellseq-Epithelial-Epithelial_Neuro-Secretory-PNEC|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SYT14 ADAMTS18 APLP1 CHGB RET

5.29e-0519194512ea07565dc0e62cade9fbab4a2d763e47a341e3
ToppCell15-Trachea-Epithelial-Neuroendocrine|Trachea / Age, Tissue, Lineage and Cell class

PKD2L1 APLP1 CHGB RET FREM1

5.29e-0519194576311fa5f3ae9bb27cf04387a8c92300f2888c28
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SPSB1 PLA2G4A SORBS1 GRIN2A ADH1B

5.29e-0519194539092a0aff8097617820c59f5fea9ee2bb4f63a2
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SPSB1 PLA2G4A SORBS1 GRIN2A ADH1B

5.29e-05191945ee5f1b1c59029c46cbb1a00935c03b9317bb9da9
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SPSB1 PLA2G4A SORBS1 GRIN2A ADH1B

5.42e-05192945bc84b9ce01b4d826a682842ab8a395dac9b91183
ToppCell5'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CALCR PCLO APLP1 CHGB F10

5.42e-051929455692bd57093852d442400383850f416c497dcc7d
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SPSB1 PLA2G4A SORBS1 GRIN2A ADH1B

5.42e-051929450ab1176cfbb0de8dd1f22c6e2c41265cf6c10ee1
ToppCellfacs-Pancreas-Endocrine|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HEXA APLP1 CHGB GNAS IDS

5.56e-0519394515c86e20b97b6983410b36d308cddff56d141c98
ToppCellcellseq-Epithelial-Epithelial_Neuro-Secretory|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SYT14 ADAMTS18 APLP1 CHGB RET

5.56e-0519394525b1e5a04724023918c8939109a92b35582d5e5c
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

CASS4 MAGI2 IL16 KITLG ADH1B

5.69e-05194945e93de9428c986b8943fc169258847c650cfab0e5
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SPSB1 PLA2G4A SORBS1 GRIN2A ADH1B

5.69e-05194945cf0244a29934e515446ac917d3c30672b460fb04
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SPSB1 PLA2G4A SORBS1 GRIN2A ADH1B

5.69e-05194945ba7f971fb9a19423602da60770f23d9fead4a451
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SH3PXD2A NISCH APLP1 CHGB PRLR

5.69e-051949450b023de48ed8a550d169bbe954881eb04bf4f981
ToppCelldroplet-Spleen-SPLEEN-30m-Lymphocytic-plasma_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RHOB CACNA1S WNT10A PRLR HDLBP

5.83e-05195945f9a90cd7b4e99a0947fdb3645f7787d02b0f7ca0
ToppCellfacs-Pancreas-Endocrine-18m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SH3PXD2A PCLO RET IDS PRLR

5.83e-05195945bd8e24dd598990204998d1dd853ba7a53dc0107e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SPSB1 PLA2G4A SORBS1 GRIN2A ADH1B

5.83e-05195945edd4cd8402af81737b2074f9dce71cc6ab09be7e
ToppCell(08)_PNEC|World / shred by cell type and Timepoint

PCLO APLP1 CHGB RET MCF2L

5.98e-051969452ee37155c03cd5009427a4bffe6c80ed2ac6939e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SPSB1 PLA2G4A SORBS1 GRIN2A ADH1B

6.12e-05197945ae0435f4b4a9cdedb1c201fc56921048390097bf
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SPSB1 PLA2G4A SORBS1 GRIN2A ADH1B

6.12e-0519794537f6b6f2809b952382eaebb642b0aad6371f4251
ToppCell3'-GW_trimst-1-SmallIntestine-Neuronal-neurons_A-Branch_A2_(IPAN/IN)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NRXN2 SYT14 APLP1 CHGB RET

6.12e-05197945f7eaac1c321710a55e09ffb047a7db2baf7b7e28
ToppCellBronchial-10x5prime-Epithelial-Epi_airway_neuro-secretory|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

SYT14 PKD2L1 APLP1 CHGB RET

6.27e-051989452591e08e3fbee86ac40f11becd8147d6d39fded6
ToppCell3'-GW_trimst-1-SmallIntestine-Neuronal-neurons_A|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NRXN2 SYT14 APLP1 CHGB RET

6.42e-05199945ce8dbfd969b3b9c08e1c57c2bfd899818e878731
ToppCellNon-neuronal-Dividing-IPC-IPC-div2|World / Primary Cells by Cluster

BLM PTTG1 NEUROG1 SMC1A KNL1

6.58e-052009454923d7a4f00853c4d76fc1cc0fa82d522a2302e7
ToppCellNon-neuronal-Dividing-IPC-IPC-div2-5|World / Primary Cells by Cluster

BLM PTTG1 NEUROG1 SMC1A KNL1

6.58e-05200945dc1c1506823eaa105f1532c6b5d4efa14e788314
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-AC-like-AC-like_Prolif-A|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PTTG3P PTTG1 KCNQ2 PTTG2

1.52e-04127944aca98d8c91f2aa0a777b6e9480c9ea70d38ff393
ToppCellPBMC-Control-Myeloid-Neutrophil-Neutrophil-Neu_1|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CASS4 CYP4F2 CYP4F3 CHGB

2.33e-04142944191a13bba143ecdfc2bfd797c3ac191481388298
ToppCellPBMC-Mild-Myeloid-Neutrophil-immature_Neutrophil-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

TOGARAM1 RET PLXNB1 PTTG2

2.33e-04142944e160f35b3c18e77c4107fe96db5f56227c91785e
ToppCellPBMC-Control-Myeloid-Neutrophil-Neutrophil-Neu_1|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CASS4 CYP4F2 CYP4F3 CHGB

2.39e-04143944b405dba9a83a99cc7b53ce71772bc52a0bbb0d4e
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-AC-like-AC-like_Prolif|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PTTG3P PTTG1 KCNQ2 PTTG2

3.02e-04152944f748ee34167f79ecda116aa1914afab47403385a
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Granulocytic-Neutrophil-Neu_c6-FGF23|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PCYT1A APLP1 PLCB2 CYP4F3

3.02e-041529440652ee3443e6fbb679d2c4f326239ae7c803f924
ToppCell343B-Lymphocytic-CD4_T-cell-Treg_cell_1|343B / Donor, Lineage, Cell class and subclass (all cells)

PCF11 POLE TOGARAM1 PLCB2

3.25e-04155944a4ff78e2efc6fe9a513bb2b64e5848f2ce65a09f
ToppCellE18.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-Sox9_Epi-Sox9_Epi_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ARHGEF33 POLE ADAMTS18 IGSF9

3.33e-04156944b28bbdb515317368f1231b0b15d7442352f3b400
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SPSB1 APBA1 APLP1 SORBS1

3.33e-04156944d5207dbfbcfb885557ea1378dfe6a56d7102e94a
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SPSB1 APBA1 APLP1 SORBS1

3.33e-04156944363f1b661048d25895e2b8681c82894c957b29c0
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L6_IT|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CPA6 CAPN3 ADAMTS18 WNT10A

3.49e-041589449e0589f770920f8ac41cfe5cd0a29e9e7a04a308
ToppCellHippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Krt73-Inhibitory_Gad1Gad2_Htr3a.Krt73_(Interneuron,__(candidate_CGE-derived_8))-|Hippocampus / BrainAtlas - Mouse McCarroll V32

ADAMTS18 F10 FREM1

3.51e-0465943a3aac8aada31451c33165257773daaae676ad04e
ToppCellHippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Krt73|Hippocampus / BrainAtlas - Mouse McCarroll V32

ADAMTS18 F10 FREM1

3.51e-046594302e778b500f62e5fb70e2f7d493a0280980e6a24
ToppCellHippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Krt73-Inhibitory_Gad1Gad2_Htr3a.Krt73_(Interneuron,__(candidate_CGE-derived_8))|Hippocampus / BrainAtlas - Mouse McCarroll V32

ADAMTS18 F10 FREM1

3.51e-0465943af69f27937e6c55ae937f16c418ff267c3ba6a8a
ToppCellPND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

BLM SEMA3D APBA1 IGSF9

3.58e-041599447ed659163f45e0c4df4782997c0786900c8186c8
ToppCellfacs-Large_Intestine-Distal-18m-Epithelial-Goblet_cell,_top_of_crypt_(Distal)|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RHOB SH3PXD2A MCF2L F10

3.58e-04159944c9e093d7c1dca83f6546adaf3d874929e2cea612
ToppCellPND07-Endothelial-Endothelial_lymphatic|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SEMA3D CELSR1 NRXN2 GNAS

3.75e-04161944133b4fadb499e842c19f573f9cf09ce08c1d4813
ToppCellPND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SEMA3D CELSR1 NRXN2 GNAS

3.75e-041619449466b8658244116f8d21f2f88fb8c2d184b1bdf2
ToppCellPND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SEMA3D CELSR1 NRXN2 GNAS

3.75e-04161944cb177ca10d848d0e25399ab5ebfcde1071fb94c2
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma|TCGA-Brain / Sample_Type by Project: Shred V9

PLCB2 SORBS1 PAF1 PLXNB1

3.84e-04162944810881210e015c788814e4fe8d7a24c929cf2621
ToppCellPND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SEMA3D CELSR1 NRXN2 GNAS

3.84e-0416294496c6e94a10b124a1d25dcd705ec5aaa8609c1089
ToppCellCOVID-19-lung-Mesothelial|COVID-19 / Disease (COVID-19 only), tissue and cell type

PLA2G4A IGSF9 SLC39A8 ADH1B

4.02e-0416494483303e2ba52008391b8dc3fae8225ab5bcb20063
ToppCellClub-club-2|World / Class top

RHOB SEMA3D SLC39A8 HDLBP

4.21e-0416694456f11efb6b686b3ee2c34a051f626e3d761b5112
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NISCH PAN2 CHGB PRLR

4.31e-04167944b94e8ee8c3fcebedd8fcd719eadddc04c7513c50
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

BLM PTTG1 POLE KNL1

4.50e-04169944b253a4a50c06d36228fcd5d856c57202cbac158f
ToppCell368C-Myeloid-Macrophage-SPP1+_Macrophage_2|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

PIK3R4 KITLG POLE APBA1

4.50e-04169944ea600c63cf9572bc4b3cad6392f67bd0d92c7fc9
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-proliferative_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PLA2G4A SORBS1 GRIN2A ADH1B

4.50e-04169944a84490724a206c9bbb145f7ce08613f91d100ac4
ToppCellwk_15-18-Epithelial-Proximal_epithelial-Pulmonary_NE_precursor|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

PCLO PKD2L1 APLP1 CHGB

4.60e-0417094498d13dbd76a826e47d55553f9d11f71c043b573e
DrugCrotamiton [483-63-6]; Up 200; 19.6uM; MCF7; HT_HG-U133A

SMC1A PRRG3 CYP4F3 SORBS1 GRIN2A DICER1 PLXNB1 ADH1B

1.55e-061969485689_UP
Drugebastine

CYP4F8 CYP4F2 CYP4F3 CYP4F12

3.22e-0625944CID000003191
DrugDB08184

GTF2B PTTG1 EXOSC10 CYP4F8 CYP4F2 CYP4F3 IDS

6.03e-06167947CID009547945
Drug18-HETE

CYP4F8 CYP4F2 CYP4F12

8.01e-0610943CID006442778
DrugAC1L1AL2

CYP4F8 PLA2G4A CYP4F2 CYP4F3 CYP4F12 PAF1

8.26e-06115946CID000001035
Drug4-bromophenol

BLM CYP4F8 NISCH CYP4F12 PRLR

1.05e-0570945CID000007808
Drugcarteolol

CYP4F8 CYP4F2 CYP4F3 CYP4F12 PAF1

1.21e-0572945CID000002583
Drugchloral hydrate

CYP4F8 CYP4F2 CYP4F3 CYP4F12 GRIN2A ADH1B

1.59e-05129946CID000002707
DrugThyroxine (L) [51-48-9]; Up 200; 5.2uM; PC3; HT_HG-U133A

PCYT1A NRXN2 SH3PXD2A SMC1A APBA1 CLUL1 ADH1B

1.77e-051979474069_UP
Drugazo analog I

CYP4F8 CYP4F3 CYP4F12

1.89e-0513943CID006438575
DrugAC1O5PIQ

CYP4F8 CYP4F2 CYP4F3 CYP4F12

2.01e-0539944CID006438348
Drugdeca

HEXA RPS6KA3 IGSF9 CNGA2

2.01e-0539944CID000002993
Drugdichloran

CYP4F8 CYP4F2 CYP4F3 CYP4F12

2.45e-0541944CID000007430
DrugCelecoxib

ANKRD13D BLM RHOB PLA2G4A CYP4F3 GRIN2A MAPK1 GNAS TTC33

2.57e-05376949ctd:D000068579
DrugEthylnitrosourea

BLM PTTG1 CELSR1 KCNQ2 CHGB GNAS DICER1 FREM1

2.78e-05291948ctd:D005038
Drugdiamidine

PKD2L1 CYP4F2 CYP4F3

2.99e-0515943CID000008813
DrugAC1L9KQO

HEXA PCYT1A CACNA1S EXOSC10

5.01e-0549944CID000447335
DiseaseSchizophrenia

MAGI2 SEMA3D NEUROG1 NRXN2 SH3PXD2A PLA2G4A KCNQ2 GRIN2A MAPK1 CHGB GNAS ADNP DICER1

2.14e-068838813C0036341
Diseasefamilial medullary thyroid carcinoma (implicated_via_orthology)

RET PRLR

8.79e-062882DOID:0050547 (implicated_via_orthology)
DiseaseSex Cord-Stromal Tumor

GNAS DICER1

8.79e-062882C0206724
DiseaseNeurodevelopmental Disorders

SMC1A KCNQ2 ADNP PLXNB1 CASK

8.89e-0693885C1535926
Diseasetooth agenesis

CACNA1S WNT10A EDA

3.79e-0522883EFO_0005410
DiseaseCongenital absence of kidneys syndrome

RET FREM1

8.74e-055882C1609433
Diseaseprostate cancer (implicated_via_orthology)

POLE PRPF8 HDLBP

1.31e-0433883DOID:10283 (implicated_via_orthology)
DiseaseAutistic Disorder

NRXN2 PLA2G4A GRIN2A ADNP PRLR HDLBP

1.34e-04261886C0004352
Diseaseintraocular pressure measurement

PNPT1 GTF2B EXOSC10 SH3PXD2A PCLO ADAMTS18 EDA HDLBP

1.43e-04509888EFO_0004695
Diseasecolorectal adenocarcinoma (is_implicated_in)

IL16 CYP4F8 MAPK1

1.57e-0435883DOID:0050861 (is_implicated_in)
Diseaseskin aging measurement

PNPT1 KITLG WNT10A PRLR SLC39A8

2.13e-04181885EFO_0008006
DiseaseUnilateral agenesis of kidney

RET FREM1

2.43e-048882C0266294
DiseaseColorectal Carcinoma

GTF2B POLE PAN2 ADAMTS18 GRIN2A GNAS RET EDA ADH1B

2.49e-04702889C0009402
Diseasemargarate 17:0 measurement

PKD2L1 FREM1

3.12e-049882EFO_0021066
DiseaseMotor retardation

RPS6KA3 SYT14

3.12e-049882C0424230
DiseasePituitary Adenoma

GNAS DICER1

3.12e-049882C0032000
DiseaseIntellectual Disability

HEXA PNPT1 SNX14 NRXN2 GNAS PJA1 NSUN2

3.86e-04447887C3714756
Diseasetooth agenesis (is_implicated_in)

WNT10A EDA

3.90e-0410882DOID:0050591 (is_implicated_in)
Diseasedecadienedioic acid (C10:2-DC) measurement

PKD2L1 DCAF4

3.90e-0410882EFO_0800598
Diseasecannabis dependence measurement

SEMA3D ARHGEF33 RET

4.02e-0448883EFO_0008457
Diseasehyperhomocysteinemia (implicated_via_orthology)

GRIN2A F10

4.75e-0411882DOID:9279 (implicated_via_orthology)
DiseaseAshkenazi Jewish disorders

BLM HEXA

4.75e-0411882cv:CN118946
DiseaseOligodontia

WNT10A EDA

5.69e-0412882C4082304
DiseaseMalignant Neoplasms

BLM GNAS RET DICER1

5.94e-04128884C0006826
Diseasealcohol dependence measurement

ARHGAP21 SLC39A8 ADH1B

6.01e-0455883EFO_0007835
Diseaseecosanoids measurement

PKD2L1 CYP4F2 ADH1B

6.01e-0455883EFO_0020044
Diseasebitter alcoholic beverage consumption measurement

NRXN2 SYT14 SLC39A8 ADH1B

6.86e-04133884EFO_0010092
DiseaseWithdrawal Symptoms

GRIN2A MAPK1 GNAS

7.02e-0458883C0087169
DiseaseDrug Withdrawal Symptoms

GRIN2A MAPK1 GNAS

7.02e-0458883C0086189
DiseaseSubstance Withdrawal Syndrome

GRIN2A MAPK1 GNAS

7.02e-0458883C0038587
Diseasefibrinogen measurement, factor VII measurement

CAPN3 MCF2L HDLBP

7.02e-0458883EFO_0004619, EFO_0004623
DiseaseHypodontia

WNT10A EDA

7.82e-0414882C0020608
DiseaseMAJOR AFFECTIVE DISORDER 2

MAGI2 KCNQ2

1.16e-0317882C1839839
DiseaseCongenital Intestinal Aganglionosis

SEMA3D RET

1.16e-0317882C3661523
Diseasepolycystic kidney disease (biomarker_via_orthology)

PLA2G4A GNAS

1.45e-0319882DOID:0080322 (biomarker_via_orthology)
DiseaseCarcinoma

BLM KITLG PRLR CASK

1.49e-03164884C0007097
Diseasecoagulation factor measurement

MCF2L F10

1.61e-0320882EFO_0004634
Diseasehigh density lipoprotein particle size measurement

NISCH SLC39A8 KNL1 HDLBP

1.70e-03170884EFO_0008592
Diseasegastric ulcer

GNAS TTC33

1.78e-0321882EFO_0009454
Diseasesaturated fatty acids to total fatty acids percentage

PKD2L1 ADH1B

1.78e-0321882EFO_0022305
Diseaseprothrombin time measurement

MCF2L F10

1.78e-0321882EFO_0008390
DiseaseEpilepsy, Cryptogenic

SMC1A KCNQ2 GRIN2A

1.91e-0382883C0086237
DiseaseAwakening Epilepsy

SMC1A KCNQ2 GRIN2A

1.91e-0382883C0751111
DiseaseAura

SMC1A KCNQ2 GRIN2A

1.91e-0382883C0236018
Diseasealcohol use disorder measurement, alcohol dependence

SLC39A8 ADH1B

2.33e-0324882EFO_0009458, MONDO_0007079
Diseaseblood urea nitrogen measurement

GTF2B PLA2G4A GNAS PRLR TTC33 ADH1B

2.35e-03452886EFO_0004741
Diseasecardiovascular disease

GTF2B PKD2L1 SORBS1 MCF2L FREM1 ADH1B

2.48e-03457886EFO_0000319
Diseasecongestive heart failure (is_implicated_in)

SMC1A NISCH

2.94e-0327882DOID:6000 (is_implicated_in)

Protein segments in the cluster

PeptideGeneStartEntry
SDSPSFFEEKPEEPV

ADNP

736

Q9H2P0
SSVPELPGFYFDPEK

DCAF4

61

Q8WV16
PTAISPEEYFDPNFS

ANKRD13D

326

Q6ZTN6
FPLDEDVSYKVPSSF

CASS4

321

Q9NQ75
PDYFPDFDPSEKVTK

CALCR

96

P30988
DFDTPDYTRPKEEFV

AFTPH

46

Q6ULP2
PFSIEDVEVAPPKAY

ADH1B

21

P00325
EIFALPAPYDEEPFQ

ARHGEF33

621

A8MVX0
TIPDDYKEDPSRFPD

ANKRD13C

526

Q8N6S4
EESFPQPVDDYFVEP

APLP1

246

P51693
VSFPADFFRPPEEKE

CELSR1

2281

Q9NYQ6
PLSKFPSPEYETFAE

DICER1

956

Q9UPY3
TYCGPFPESEPEVKA

CPA6

291

Q8N4T0
APKPPTEDTYLRFDE

ADAMTS18

261

Q8TE60
KEDPFVFIPEDDPLF

NSUN2

516

Q08J23
DDPLFPPIEKFYALD

NSUN2

526

Q08J23
YYDPSDEPIAEAPFK

MAPK1

316

P28482
YGVPFEFPPEAQSKD

PDHB

206

P11177
PEPSFNPYSRETEFA

PAN2

361

Q504Q3
KFNSFYGDPPEELPD

CASK

316

O14936
STEAFDPRKPDPYEL

MAGI2

731

Q86UL8
EDFTYRPGDPVFSFP

NEUROG1

206

Q92886
PATGRPEDTFYFDPE

RPS6KA3

346

P51812
PEDTFYFDPEFTAKT

RPS6KA3

351

P51812
YFDPEFTAKTPKDSP

RPS6KA3

356

P51812
LESAFVPYEKPLPDD

PCLO

3636

Q9Y6V0
PFSDEIEVDFSKPYV

PCYT1A

46

P49585
PPDPQAAFSYEETAK

PLXNB1

191

O43157
PPTETEAYFGAKEPE

KCNQ2

651

O43526
DASDDYIFFNITKPP

FREM1

551

Q5H8C1
SDDGSSPDEKYPDPF

IL16

31

Q14005
SPDEKYPDPFEISLA

IL16

36

Q14005
PPTDDEDFYTTFPLV

NRXN2

1506

Q9P2S2
YSPKEFATPDYTPEL

MYCLP1

116

P12525
FPDVPDKENFEIPIY

KNL1

256

Q8NG31
EFTPKPEYEGPFCVF

POLE

321

Q07864
PVEKPKPEDDFPDNY

PPP4R3B

731

Q5MIZ7
PRYEDSDKPFVDSPA

PCF11

716

O94913
KAHFDYDPSDDPYVP

PALS1

351

Q8N3R9
DIPFDPKFITYPFDQ

PAF1

41

Q8N7H5
LNFFFPDEKPYSEEE

EDA

136

Q92838
KDPEPPEKEFTPYDY

EXOSC10

806

Q01780
KFFPGPLSPEEEDVF

CEFIP

696

Q711Q0
FDDDDYDTDFVPPSP

BLM

291

P54132
EVKDPYPSADFPGDD

CACNA1S

731

Q13698
DPEVYDPFRFDPENA

CYP4F8

436

P98187
DPEVYDPFRFDPENS

CYP4F12

436

Q9HCS2
SDSPEKEAEFAPYPR

APBA1

246

Q02410
DPEVYDPFRFDPENI

CYP4F2

436

P78329
TFPDYPAFSEIPDKE

MCF2L

96

O15068
IPPEADKEEPRSFFF

FAM172BP

81

A6NC97
DPEVYDPFRFDPKNI

CYP4F3

436

Q08477
PEAGEKLFPYLDPFD

IDS

371

P22304
KAIFDTPDEDPNYNP

DERL2

206

Q9GZP9
LPKDYAFTFFDPNDP

CLIP3

51

Q96DZ5
KPYDAADLDPTENPF

F10

201

P00742
VDPEFPPDETSLFYS

CAPN3

76

P20807
KSAEFPDFYDSEEPV

CHGB

616

P05060
ASDDAYPEIEKFFPF

PTTG1

106

O95997
TLYSHPDFPEKGPEE

PLA2G4A

236

P47712
VDDPSFPYESFTFPE

HEXA

206

P06865
FQDPFSLTEKPPAEF

RUSC2

961

Q8N2Y8
SKDEFPEVYVPTVFE

RHOB

26

P62745
KPFDPEPEAKYGTLD

SYT14

251

Q8NB59
LYKFPEDKSETDFPD

SYT15

131

Q9BQS2
PDFDFPPEFYEHAKA

GNAS

781

Q5JWF2
PEFARYTTPEDATPE

GNAS

956

Q5JWF2
ASDDGYPEIEKLFPF

PTTG3P

106

Q9NZH4
SFKSPEPRLFTPEEF

KITLG

126

P21583
ASDDAYPEIEKFFPF

PTTG2

106

Q9NZH5
EKFPEADPYEIIESF

PNPT1

326

Q8TCS8
TFFIPDTYNPDDDKI

SEMA3D

246

O95025
TPPPVKDEEYLFVIF

CNGA2

341

Q16280
TDLTEPYFFPAFSKE

CLUL1

221

Q15846
DFASFKPTYLPEDNP

PIK3R4

166

Q99570
KTEDPDLPAFYFDPL

PRPF8

341

Q6P2Q9
KISIPYVDFFEDPSS

SNX14

566

Q9Y5W7
YPAFLEPDETFIVPD

SPSB1

161

Q96BD6
APDLFPTDFKFDTPV

GTF2B

296

Q00403
FEARPEDVNPPKEDY

SH3PXD2A

121

Q5TCZ1
FLDITFSSDYPFKPP

UBE2E3

111

Q969T4
YQFPASTPSPKSEDD

SORBS1

441

Q9BX66
RTPSPEPVDKDFYSE

NISCH

1281

Q9Y2I1
PSTFYDPEVIEKPEN

PRLR

371

P16471
SYKPAPFFVLDEIDA

SMC1A

1146

Q14683
APPAFIERPKEEYFQ

IGSF9

416

Q9P2J2
FTYGPSFPAFKVPDE

RALGAPB

251

Q86X10
VYSPDKEEQLPFGPF

PKD2L1

226

Q9P0L9
DAINPEDFPEPVYKS

PLCB2

196

Q00722
VPFPVTVYDEDDSAP

RET

256

P07949
LIPEAFGFDPKVDSY

SLC39A8

181

Q9C0K1
SEEESDPPTYKDAFP

HDLBP

31

Q00341
YPSEDFDLPKLSFDL

TOGARAM1

501

Q9Y4F4
SFHPVEDFPAPEEYK

WIPF2

401

Q8TF74
ASPADLVYFEKSPDF

WNT10A

331

Q9GZT5
PEPLFTNDKYADFIE

ARHGAP21

1231

Q5T5U3
ESSSGYPEPKYPEDK

PJA1

311

Q8NG27
EEASVSYSDPPPKYE

PRRG3

206

Q9BZD7
SYSDPPPKYEEIVAA

PRRG3

211

Q9BZD7
EEVKFYLPPTPGSEF

YEATS2

1316

Q9ULM3
FSPKSIPDYDFESDE

TTC33

196

Q6PID6
ADFPPPEEAFFSVAS

KIAA1522

726

Q9P206
DFPDPYQDPSENFRK

GRIN2A

1146

Q12879