Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	inositol 1,4,5-trisphosphate-gated calcium channel activity	ITPR1 ITPR2	3.73e-05	3	71	2	GO:0005220
GeneOntologyMolecularFunction	cytoskeleton-nuclear membrane anchor activity	SYNE1 SYNE2	1.24e-04	5	71	2	GO:0140444
GeneOntologyCellularComponent	anchoring collagen complex	COL12A1 COL14A1	3.40e-05	3	71	2	GO:0030934
GeneOntologyCellularComponent	FACIT collagen trimer	COL12A1 COL14A1	1.69e-04	6	71	2	GO:0005593
GeneOntologyCellularComponent	nuclear outer membrane	SYNE1 SYNE2 NAV3	3.39e-04	40	71	3	GO:0005640
GeneOntologyCellularComponent	extracellular matrix	RELN COL12A1 DST VCAN COL14A1 REG1B MMP20 IFNA2 ITIH5	3.67e-04	656	71	9	GO:0031012
GeneOntologyCellularComponent	external encapsulating structure	RELN COL12A1 DST VCAN COL14A1 REG1B MMP20 IFNA2 ITIH5	3.75e-04	658	71	9	GO:0030312
GeneOntologyCellularComponent	platelet dense tubular network membrane	ITPR1 ITPR2	4.03e-04	9	71	2	GO:0031095
GeneOntologyCellularComponent	collagen-containing extracellular matrix	RELN COL12A1 DST VCAN COL14A1 REG1B IFNA2 ITIH5	4.24e-04	530	71	8	GO:0062023
GeneOntologyCellularComponent	microtubule organizing center attachment site	SYNE1 SYNE2	6.13e-04	11	71	2	GO:0034992
GeneOntologyCellularComponent	meiotic nuclear membrane microtubule tethering complex	SYNE1 SYNE2	6.13e-04	11	71	2	GO:0034993
GeneOntologyCellularComponent	nuclear membrane protein complex	SYNE1 SYNE2	6.13e-04	11	71	2	GO:0106083
GeneOntologyCellularComponent	nuclear membrane microtubule tethering complex	SYNE1 SYNE2	6.13e-04	11	71	2	GO:0106094
GeneOntologyCellularComponent	platelet dense tubular network	ITPR1 ITPR2	6.13e-04	11	71	2	GO:0031094
GeneOntologyCellularComponent	A band	DST ANK2 MYOM1	7.36e-04	52	71	3	GO:0031672
GeneOntologyCellularComponent	filopodium	UBE2K SYNE2 UTRN DYNC1H1	8.18e-04	123	71	4	GO:0030175
GeneOntologyCellularComponent	sarcomere	DST ANK2 MYOM1 SYNE1 SYNE2	1.58e-03	249	71	5	GO:0030017
GeneOntologyCellularComponent	filopodium membrane	SYNE2 UTRN	2.29e-03	21	71	2	GO:0031527
GeneOntologyCellularComponent	myofibril	DST ANK2 MYOM1 SYNE1 SYNE2	2.36e-03	273	71	5	GO:0030016
GeneOntologyCellularComponent	nuclear envelope	UTP18 DST SYNE1 SYNE2 NAV3 DYNC1H1 ITPR1	2.88e-03	560	71	7	GO:0005635
GeneOntologyCellularComponent	contractile muscle fiber	DST ANK2 MYOM1 SYNE1 SYNE2	3.06e-03	290	71	5	GO:0043292
GeneOntologyCellularComponent	sarcoplasmic reticulum	SYNE2 ITPR1 ITPR2	3.35e-03	88	71	3	GO:0016529
Domain	Actinin_actin-bd_CS	DST SYNE1 SYNE2 UTRN	1.43e-06	23	69	4	IPR001589
Domain	Spectrin	DST SYNE1 SYNE2 UTRN	1.43e-06	23	69	4	PF00435
Domain	ACTININ_2	DST SYNE1 SYNE2 UTRN	1.43e-06	23	69	4	PS00020
Domain	ACTININ_1	DST SYNE1 SYNE2 UTRN	1.43e-06	23	69	4	PS00019
Domain	Spectrin_repeat	DST SYNE1 SYNE2 UTRN	3.78e-06	29	69	4	IPR002017
Domain	CH	DST SYNE1 SYNE2 NAV3 UTRN	4.13e-06	65	69	5	SM00033
Domain	Spectrin/alpha-actinin	DST SYNE1 SYNE2 UTRN	5.67e-06	32	69	4	IPR018159
Domain	SPEC	DST SYNE1 SYNE2 UTRN	5.67e-06	32	69	4	SM00150
Domain	CH	DST SYNE1 SYNE2 NAV3 UTRN	5.97e-06	70	69	5	PF00307
Domain	-	DST SYNE1 SYNE2 NAV3 UTRN	6.40e-06	71	69	5	1.10.418.10
Domain	CH	DST SYNE1 SYNE2 NAV3 UTRN	7.34e-06	73	69	5	PS50021
Domain	CH-domain	DST SYNE1 SYNE2 NAV3 UTRN	8.39e-06	75	69	5	IPR001715
Domain	InsP3_rcpt-bd	ITPR1 ITPR2	4.03e-05	3	69	2	IPR000493
Domain	KASH	SYNE1 SYNE2	8.03e-05	4	69	2	PF10541
Domain	KASH	SYNE1 SYNE2	8.03e-05	4	69	2	IPR012315
Domain	KASH	SYNE1 SYNE2	8.03e-05	4	69	2	PS51049
Domain	KASH	SYNE1 SYNE2	8.03e-05	4	69	2	SM01249
Domain	RIH_assoc	ITPR1 ITPR2	2.00e-04	6	69	2	PF08454
Domain	RIH_assoc-dom	ITPR1 ITPR2	2.00e-04	6	69	2	IPR013662
Domain	RIH_dom	ITPR1 ITPR2	2.00e-04	6	69	2	IPR000699
Domain	Ins145_P3_rcpt	ITPR1 ITPR2	2.00e-04	6	69	2	IPR014821
Domain	Ryanodine_recept-rel	ITPR1 ITPR2	2.00e-04	6	69	2	IPR015925
Domain	-	ITPR1 ITPR2	2.00e-04	6	69	2	1.25.10.30
Domain	RYDR_ITPR	ITPR1 ITPR2	2.00e-04	6	69	2	PF01365
Domain	Ins145_P3_rec	ITPR1 ITPR2	2.00e-04	6	69	2	PF08709
Domain	G-protein_beta_WD-40_rep	SNRNP40 WDR18 WDR1 SPAG16	2.76e-04	85	69	4	IPR020472
Domain	WD40_repeat_CS	UTP18 SNRNP40 WDR18 WDR1 SPAG16	3.51e-04	164	69	5	IPR019775
Domain	MIR	ITPR1 ITPR2	5.94e-04	10	69	2	PS50919
Domain	MIR	ITPR1 ITPR2	5.94e-04	10	69	2	PF02815
Domain	MIR	ITPR1 ITPR2	5.94e-04	10	69	2	SM00472
Domain	MIR_motif	ITPR1 ITPR2	5.94e-04	10	69	2	IPR016093
Domain	FN3	COL12A1 MYOM1 COL14A1 HCFC2 LEPR	6.08e-04	185	69	5	SM00060
Domain	FN3	COL12A1 MYOM1 COL14A1 HCFC2 LEPR	8.45e-04	199	69	5	PS50853
Domain	Mab-21_dom	CGAS TMEM102	8.67e-04	12	69	2	IPR024810
Domain	Mab-21	CGAS TMEM102	8.67e-04	12	69	2	PF03281
Domain	Mab-21	CGAS TMEM102	8.67e-04	12	69	2	SM01265
Domain	FN3_dom	COL12A1 MYOM1 COL14A1 HCFC2 LEPR	1.05e-03	209	69	5	IPR003961
Domain	VWA	COL12A1 COL14A1 ITIH5	1.16e-03	56	69	3	PF00092
Domain	N2O_reductase_N	SNRNP40 WDR1	1.37e-03	15	69	2	IPR011045
Domain	Interferon_alpha/beta/delta	IFNA2 IFNA5	1.76e-03	17	69	2	IPR000471
Domain	Interferon	IFNA2 IFNA5	1.76e-03	17	69	2	PF00143
Domain	IFabd	IFNA2 IFNA5	1.76e-03	17	69	2	SM00076
Domain	INTERFERON_A_B_D	IFNA2 IFNA5	1.76e-03	17	69	2	PS00252
Domain	-	COL12A1 COL14A1 ITIH5	2.59e-03	74	69	3	3.40.50.410
Domain	WD40	UTP18 SNRNP40 WDR18 WDR1 SPAG16	2.69e-03	259	69	5	PF00400
Domain	fn3	COL12A1 MYOM1 COL14A1 HCFC2	3.04e-03	162	69	4	PF00041
Domain	WD40	UTP18 SNRNP40 WDR18 WDR1 SPAG16	3.12e-03	268	69	5	SM00320
Domain	TSPN	COL12A1 COL14A1	3.24e-03	23	69	2	SM00210
Domain	WD40_repeat	UTP18 SNRNP40 WDR18 WDR1 SPAG16	3.32e-03	272	69	5	IPR001680
Domain	VWFA	COL12A1 COL14A1 ITIH5	3.47e-03	82	69	3	PS50234
Domain	WD_REPEATS_1	UTP18 SNRNP40 WDR18 WDR1 SPAG16	3.65e-03	278	69	5	PS00678
Domain	WD_REPEATS_2	UTP18 SNRNP40 WDR18 WDR1 SPAG16	3.70e-03	279	69	5	PS50082
Domain	WD_REPEATS_REGION	UTP18 SNRNP40 WDR18 WDR1 SPAG16	3.70e-03	279	69	5	PS50294
Domain	VWA	COL12A1 COL14A1 ITIH5	3.71e-03	84	69	3	SM00327
Domain	DEATH	THOC1 ANK2	4.45e-03	27	69	2	SM00005
Domain	WD40_repeat_dom	UTP18 SNRNP40 WDR18 WDR1 SPAG16	4.82e-03	297	69	5	IPR017986
Domain	VWF_A	COL12A1 COL14A1 ITIH5	5.88e-03	99	69	3	IPR002035
Domain	Death	THOC1 ANK2	6.60e-03	33	69	2	PF00531
Pathway	KEGG_MEDICUS_REFERENCE_CGAS_STING_SIGNALING_PATHWAY	CGAS IFNA2 IFNA5	4.16e-05	18	54	3	M47539
Pathway	REACTOME_ASSEMBLY_OF_COLLAGEN_FIBRILS_AND_OTHER_MULTIMERIC_STRUCTURES	COL12A1 DST COL14A1 MMP20	8.54e-05	61	54	4	M27103
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PRKN_TO_MGLUR1_SIGNALING_PATHWAY	ITPR1 ITPR2	1.43e-04	5	54	2	M49000
Pathway	KEGG_MEDICUS_REFERENCE_CA2_PLCD_ITPR_SIGNALING_PATHWAY	ITPR1 ITPR2	2.14e-04	6	54	2	M47960
Pathway	KEGG_REGULATION_OF_AUTOPHAGY	ATG4C IFNA2 IFNA5	3.19e-04	35	54	3	M6382
Pathway	REACTOME_COLLAGEN_FORMATION	COL12A1 DST COL14A1 MMP20	3.85e-04	90	54	4	M631
Pathway	KEGG_MEDICUS_REFERENCE_BCR_PLCG_ITPR_SIGNALING_PATHWAY	ITPR1 ITPR2	5.10e-04	9	54	2	M47852
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SPTBN2_TO_MGLUR1_TRPC3_SIGNALING_PATHWAY	ITPR1 ITPR2	6.35e-04	10	54	2	M47661
Pathway	SIG_CHEMOTAXIS	RACGAP1 ITPR1 ITPR2	6.73e-04	45	54	3	M5193
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_PRKCG_TO_MGLUR1_TRPC3_SIGNALING_PATHWAY	ITPR1 ITPR2	7.75e-04	11	54	2	M49033
Pathway	WP_PAFAH1B1_COPY_NUMBER_VARIATION	RELN DYNC1H1	7.75e-04	11	54	2	M48106
Pathway	REACTOME_CLEC7A_DECTIN_1_INDUCES_NFAT_ACTIVATION	ITPR1 ITPR2	7.75e-04	11	54	2	M27466
Pathway	REACTOME_ASSEMBLY_OF_COLLAGEN_FIBRILS_AND_OTHER_MULTIMERIC_STRUCTURES	COL12A1 COL14A1 MMP20	9.17e-04	50	54	3	MM14796
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_PSEN1_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY	ITPR1 ITPR2	1.09e-03	13	54	2	M47696
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_SIGMAR1_TO_CA2_APOPTOTIC_PATHWAY	ITPR1 ITPR2	1.09e-03	13	54	2	M47751
Pathway	KEGG_MEDICUS_REFERENCE_MGLUR1_TRPC3_SIGNALING_PATHWAY	ITPR1 ITPR2	1.09e-03	13	54	2	M47656
Pathway	REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS	ITPR1 ITPR2	1.09e-03	13	54	2	MM14553
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	RALGAPA1 GAPVD1 DST TCERG1 SYNE2 CCSER2 RACGAP1 FNIP1 TMEM102 DZIP1 USP54 UTRN GOLGB1	1.85e-08	861	71	13	36931259
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	COL12A1 DST ANK2 MYOM1 SYNE1 SYNE2 GON4L COL14A1 DZIP1 UTRN	6.87e-08	497	71	10	23414517
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	THOC1 GAPVD1 DST SYNE1 SYNE2 SNRNP40 RACGAP1 WDR18 URB2 UTRN DYNC1H1 GOLGB1 ITPR2	1.39e-07	1024	71	13	24711643
Pubmed	Inositol-1,4,5-trisphosphate receptor regulates hepatic gluconeogenesis in fasting and diabetes.	LEPR ITPR1 ITPR2	2.84e-07	7	71	3	22495310
Pubmed	Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia.	DST ANK2 SYNE1 CCSER2 UTRN DYNC1H1	6.88e-07	151	71	6	17043677
Pubmed	Nuclear actin interactome analysis links actin to KAT14 histone acetyl transferase and mRNA splicing.	GAPVD1 DST TCERG1 SNRNP40 NASP WDR1 UTRN DYNC1H1 GOLGB1	9.11e-07	506	71	9	30890647
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	THOC1 UTP18 DST COMMD9 SYNE2 CGAS SNRNP40 RACGAP1 WDR18 HCFC2 WDR1 DYNC1H1 ITPR1 ITPR2	1.08e-06	1440	71	14	30833792
Pubmed	SUN1/2 and Syne/Nesprin-1/2 complexes connect centrosome to the nucleus during neurogenesis and neuronal migration in mice.	RELN SYNE1 SYNE2	2.92e-06	14	71	3	19874786
Pubmed	Multiple novel nesprin-1 and nesprin-2 variants act as versatile tissue-specific intracellular scaffolds.	SYNE1 SYNE2	4.11e-06	2	71	2	22768332
Pubmed	Collagen types XII and XIV are present in basement membrane zones during human embryonic development.	COL12A1 COL14A1	4.11e-06	2	71	2	15609093
Pubmed	Abnormal corneal endothelial maturation in collagen XII and XIV null mice.	COL12A1 COL14A1	4.11e-06	2	71	2	23599329
Pubmed	Nesprins: a novel family of spectrin-repeat-containing proteins that localize to the nuclear membrane in multiple tissues.	SYNE1 SYNE2	4.11e-06	2	71	2	11792814
Pubmed	Nesprin-1 and nesprin-2 regulate endothelial cell shape and migration.	SYNE1 SYNE2	4.11e-06	2	71	2	24931616
Pubmed	An antidepressant behaviour in mice carrying a gene-specific InsP3R1, InsP3R2 and InsP3R3 protein knockdown.	ITPR1 ITPR2	4.11e-06	2	71	2	18708078
Pubmed	Immunolocalization of type 2 inositol 1,4,5-trisphosphate receptors in cardiac myocytes from newborn mice.	ITPR1 ITPR2	4.11e-06	2	71	2	15201137
Pubmed	Syne-1 and Syne-2 play crucial roles in myonuclear anchorage and motor neuron innervation.	SYNE1 SYNE2	4.11e-06	2	71	2	17267447
Pubmed	Cholinergic augmentation of insulin release requires ankyrin-B.	ANK2 ITPR1	4.11e-06	2	71	2	20234002
Pubmed	Inositol 1,4,5-trisphosphate receptor localization and stability in neonatal cardiomyocytes requires interaction with ankyrin-B.	ANK2 ITPR1	4.11e-06	2	71	2	14722080
Pubmed	Nesprins: tissue-specific expression of epsilon and other short isoforms.	SYNE1 SYNE2	4.11e-06	2	71	2	24718612
Pubmed	Targeted ablation of nesprin 1 and nesprin 2 from murine myocardium results in cardiomyopathy, altered nuclear morphology and inhibition of the biomechanical gene response.	SYNE1 SYNE2	4.11e-06	2	71	2	24586179
Pubmed	Sulphide signalling potentiates apoptosis through the up-regulation of IP3 receptor types 1 and 2.	ITPR1 ITPR2	4.11e-06	2	71	2	23582047
Pubmed	Nesprin-1 and -2 are involved in the pathogenesis of Emery Dreifuss muscular dystrophy and are critical for nuclear envelope integrity.	SYNE1 SYNE2	4.11e-06	2	71	2	17761684
Pubmed	Ankyrin B modulates the function of Na,K-ATPase/inositol 1,4,5-trisphosphate receptor signaling microdomain.	ANK2 ITPR1	4.11e-06	2	71	2	18303017
Pubmed	Nesprin-1-alpha2 associates with kinesin at myotube outer nuclear membranes, but is restricted to neuromuscular junction nuclei in adult muscle.	SYNE1 SYNE2	4.11e-06	2	71	2	31578382
Pubmed	The COL12A1 and COL14A1 genes and Achilles tendon injuries.	COL12A1 COL14A1	4.11e-06	2	71	2	17960519
Pubmed	Type 1 and 2 IP3 receptors respond differently to catecholamines and stress.	ITPR1 ITPR2	4.11e-06	2	71	2	19120126
Pubmed	A protein interaction network for Ecm29 links the 26 S proteasome to molecular motors and endosomal components.	DST ANK2 SYNE1 GOLGB1	7.13e-06	60	71	4	20682791
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	THOC1 UTP18 DST TCERG1 CGAS SNRNP40 RACGAP1 BUD13 WDR18 WDR1 DYNC1H1 ITPR2	8.42e-06	1257	71	12	36526897
Pubmed	Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics.	COL12A1 VCAN COL14A1 IFNA2 ITIH5	8.67e-06	135	71	5	28675934
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	RALGAPA1 UTP18 ANK2 SYNE1 SYNE2 CCSER2 SNRNP40 COL14A1 DZIP1 CARS2 GOLGB1 ITPR1 ITPR2	8.70e-06	1487	71	13	33957083
Pubmed	C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.	RALGAPA1 DST SLC30A5 SYNE2 FNIP1 GOLGB1 ITPR1 ITPR2	8.80e-06	504	71	8	34432599
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	RELN DST ANK2 TCERG1 SYNE1 NAV3 NASP DZIP1 USP54 CARS2 UTRN DYNC1H1	1.05e-05	1285	71	12	35914814
Pubmed	The bHLH transcription factor Mist1 is required to maintain exocrine pancreas cell organization and acinar cell identity.	REG1B ITPR1 ITPR2	1.22e-05	22	71	3	11696558
Pubmed	Evidence that type I, II, and III inositol 1,4,5-trisphosphate receptors can occur as integral plasma membrane proteins.	ITPR1 ITPR2	1.23e-05	3	71	2	10874040
Pubmed	Expression of inositol 1,4,5-trisphosphate receptors in mouse oocytes and early embryos: the type I isoform is upregulated in oocytes and downregulated after fertilization.	ITPR1 ITPR2	1.23e-05	3	71	2	9808793
Pubmed	Ankyrin-B metabolic syndrome combines age-dependent adiposity with pancreatic β cell insufficiency.	ANK2 ITPR1	1.23e-05	3	71	2	26168218
Pubmed	Abnormal distribution of inositol 1,4,5-trisphosphate receptors in human muscle can be related to altered calcium signals and gene expression in Duchenne dystrophy-derived cells.	ITPR1 ITPR2	1.23e-05	3	71	2	20395455
Pubmed	Inositol 1,4,5-trisphosphate receptors are autoantibody target antigens in patients with Sjögren's syndrome and other systemic rheumatic diseases.	ITPR1 ITPR2	1.23e-05	3	71	2	17437169
Pubmed	Type 2 and type 3 inositol 1,4,5-trisphosphate (IP3) receptors promote the differentiation of granule cell precursors in the postnatal cerebellum.	ITPR1 ITPR2	1.23e-05	3	71	2	18194433
Pubmed	Genetic association of interferon-alpha subtypes 1, 2 and 5 in systemic lupus erythematosus.	IFNA2 IFNA5	1.23e-05	3	71	2	19000144
Pubmed	Syne-1, a dystrophin- and Klarsicht-related protein associated with synaptic nuclei at the neuromuscular junction.	SYNE1 SYNE2	1.23e-05	3	71	2	10878022
Pubmed	Decreased olfactory mucus secretion and nasal abnormality in mice lacking type 2 and type 3 IP3 receptors.	ITPR1 ITPR2	1.23e-05	3	71	2	18547250
Pubmed	Inositol 1,4,5-trisphosphate receptor gene variants are related to the risk of breast cancer in a Chinese population.	ITPR1 ITPR2	1.23e-05	3	71	2	36350267
Pubmed	Inositol 1,4,5-trisphosphate receptors are essential for fetal-maternal connection and embryo viability.	ITPR1 ITPR2	1.23e-05	3	71	2	32320395
Pubmed	IP3 receptors regulate vascular smooth muscle contractility and hypertension.	ITPR1 ITPR2	1.23e-05	3	71	2	27777977
Pubmed	The versatility and universality of calcium signalling.	ITPR1 ITPR2	1.23e-05	3	71	2	11413485
Pubmed	Using concatenated subunits to investigate the functional consequences of heterotetrameric inositol 1,4,5-trisphosphate receptors.	ITPR1 ITPR2	1.23e-05	3	71	2	26009177
Pubmed	Differential inositol 1,4,5-trisphosphate receptor signaling in a neuronal cell line.	ITPR1 ITPR2	1.23e-05	3	71	2	17581770
Pubmed	Predominant role of type 1 IP3 receptor in aortic vascular muscle contraction.	ITPR1 ITPR2	1.23e-05	3	71	2	18241669
Pubmed	The inner nuclear membrane protein Sun1 mediates the anchorage of Nesprin-2 to the nuclear envelope.	SYNE1 SYNE2	1.23e-05	3	71	2	16079285
Pubmed	Receptor-activated single channels in intact human platelets.	ITPR1 ITPR2	1.23e-05	3	71	2	1693919
Pubmed	Granulosa cells express three inositol 1,4,5-trisphosphate receptor isoforms: cytoplasmic and nuclear Ca2+ mobilization.	ITPR1 ITPR2	1.23e-05	3	71	2	19068129
Pubmed	Functional inositol 1,4,5-trisphosphate receptors assembled from concatenated homo- and heteromeric subunits.	ITPR1 ITPR2	1.23e-05	3	71	2	23955339
Pubmed	The nesprins are giant actin-binding proteins, orthologous to Drosophila melanogaster muscle protein MSP-300.	SYNE1 SYNE2	1.23e-05	3	71	2	12408964
Pubmed	Type 3 Inositol 1,4,5-Trisphosphate Receptor is a Crucial Regulator of Calcium Dynamics Mediated by Endoplasmic Reticulum in HEK Cells.	ITPR1 ITPR2	1.23e-05	3	71	2	31979185
Pubmed	Collagen XII and XIV, new partners of cartilage oligomeric matrix protein in the skin extracellular matrix suprastructure.	COL12A1 COL14A1	1.23e-05	3	71	2	22573329
Pubmed	Tsg101 regulates PI(4,5)P2/Ca(2+) signaling for HIV-1 Gag assembly.	ITPR1 ITPR2	1.23e-05	3	71	2	24904548
Pubmed	Molecular basis of the isoform-specific ligand-binding affinity of inositol 1,4,5-trisphosphate receptors.	ITPR1 ITPR2	1.23e-05	3	71	2	17327232
Pubmed	Analysis of Polymorphisms in Genes Differentially Expressed in the Enamel of Mice with Different Genetic Susceptibilities to Dental Fluorosis.	COL14A1 MMP20	1.23e-05	3	71	2	30149392
Pubmed	Distinct functional domains in nesprin-1alpha and nesprin-2beta bind directly to emerin and both interactions are disrupted in X-linked Emery-Dreifuss muscular dystrophy.	SYNE1 SYNE2	1.23e-05	3	71	2	17462627
Pubmed	Characterization of Foxp2 and Foxp1 mRNA and protein in the developing and mature brain.	RELN FOXP1	1.23e-05	3	71	2	12687690
Pubmed	Type 1 inositol (1,4,5)-trisphosphate receptor activates ryanodine receptor 1 to mediate calcium spark signaling in adult mammalian skeletal muscle.	ITPR1 ITPR2	1.23e-05	3	71	2	23223241
Pubmed	Nuclear inositol 1,4,5-trisphosphate receptors regulate local Ca2+ transients and modulate cAMP response element binding protein phosphorylation.	ITPR1 ITPR2	1.23e-05	3	71	2	16014380
Pubmed	Knockdown of the type 2 and 3 inositol 1,4,5-trisphosphate receptors suppresses muscarinic antinociception in mice.	ITPR1 ITPR2	1.23e-05	3	71	2	17890015
Pubmed	Involvement of Elf3 on Smad3 activation-dependent injuries in podocytes and excretion of urinary exosome in diabetic nephropathy.	ELF3 LEPR	1.23e-05	3	71	2	31150422
Pubmed	Inositol 1, 4, 5-trisphosphate receptors and human left ventricular myocytes.	ITPR1 ITPR2	1.23e-05	3	71	2	23983250
Pubmed	Differential distribution of inositol trisphosphate receptor isoforms in mouse oocytes.	ITPR1 ITPR2	1.23e-05	3	71	2	9858485
Pubmed	Structures of FHOD1-Nesprin1/2 complexes reveal alternate binding modes for the FH3 domain of formins.	SYNE1 SYNE2	1.23e-05	3	71	2	33472039
Pubmed	Activation of the inositol (1,4,5)-triphosphate calcium gate receptor is required for HIV-1 Gag release.	ITPR1 ITPR2	1.23e-05	3	71	2	20427533
Pubmed	Nesprins anchor kinesin-1 motors to the nucleus to drive nuclear distribution in muscle cells.	SYNE1 SYNE2	1.23e-05	3	71	2	25516977
Pubmed	PICH Supports Embryonic Hematopoiesis by Suppressing a cGAS-STING-Mediated Interferon Response.	CGAS IFNA2 IFNA5	1.60e-05	24	71	3	35037428
Pubmed	Loss of Krox20 results in aortic valve regurgitation and impaired transcriptional activation of fibrillar collagen genes.	COL12A1 VCAN COL14A1	1.60e-05	24	71	3	25344368
Pubmed	RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.	GAPVD1 TCERG1 CCSER2 USP54 UTRN GOLGB1	1.68e-05	263	71	6	34702444
Pubmed	LSm14A Plays a Critical Role in Antiviral Immune Responses by Regulating MITA Level in a Cell-Specific Manner.	CGAS IFNA2 IFNA5	1.82e-05	25	71	3	27183626
Pubmed	p62/SQSTM1 Fuels Melanoma Progression by Opposing mRNA Decay of a Selective Set of Pro-metastatic Factors.	GAPVD1 OGFOD1 UTRN GOLGB1 ITIH5	1.91e-05	159	71	5	30581152
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	SYNE1 NAV3 OGFOD1 GON4L FNIP1 URB2 DYNC1H1	1.99e-05	407	71	7	12693553
Pubmed	Loss of IP3R-dependent Ca2+ signalling in thymocytes leads to aberrant development and acute lymphoblastic leukemia.	ITPR1 ITPR2	2.46e-05	4	71	2	25215520
Pubmed	Inositol 1, 4, 5-trisphosphate receptor interacts with the SNARE domain of syntaxin 1B.	ITPR1 ITPR2	2.46e-05	4	71	2	21424589
Pubmed	SUN1 interacts with nuclear lamin A and cytoplasmic nesprins to provide a physical connection between the nuclear lamina and the cytoskeleton.	SYNE1 SYNE2	2.46e-05	4	71	2	16648470
Pubmed	LINC complexes mediate the positioning of cone photoreceptor nuclei in mouse retina.	SYNE1 SYNE2	2.46e-05	4	71	2	23071752
Pubmed	Selective regulation of IP3-receptor-mediated Ca2+ signaling and apoptosis by the BH4 domain of Bcl-2 versus Bcl-Xl.	ITPR1 ITPR2	2.46e-05	4	71	2	21818117
Pubmed	Developmental expression and intracellular location of P400 protein characteristic of Purkinje cells in the mouse cerebellum.	RELN ITPR1	2.46e-05	4	71	2	2707487
Pubmed	Loss of IP3 Receptor-Mediated Ca2+ Release in Mouse B Cells Results in Abnormal B Cell Development and Function.	ITPR1 ITPR2	2.46e-05	4	71	2	28615414
Pubmed	Distinct localization and function of (1,4,5)IP(3) receptor subtypes and the (1,3,4,5)IP(4) receptor GAP1(IP4BP) in highly purified human platelet membranes.	ITPR1 ITPR2	2.46e-05	4	71	2	10828023
Pubmed	Nesprins, but not sun proteins, switch isoforms at the nuclear envelope during muscle development.	SYNE1 SYNE2	2.46e-05	4	71	2	20108321
Pubmed	Nesprin-2 interacts with meckelin and mediates ciliogenesis via remodelling of the actin cytoskeleton.	SYNE1 SYNE2	2.46e-05	4	71	2	19596800
Pubmed	IP3R-mediated Ca2+ signals govern hematopoietic and cardiac divergence of Flk1+ cells via the calcineurin-NFATc3-Etv2 pathway.	ITPR1 ITPR2	2.46e-05	4	71	2	28419336
Pubmed	Hypoxia differently modulates gene expression of inositol 1,4,5-trisphosphate receptors in mouse kidney and HEK 293 cell line.	ITPR1 ITPR2	2.46e-05	4	71	2	19120137
Pubmed	DsbA-L prevents obesity-induced inflammation and insulin resistance by suppressing the mtDNA release-activated cGAS-cGAMP-STING pathway.	CGAS LEPR	2.46e-05	4	71	2	29087318
Pubmed	Alternative splice variants of hTrp4 differentially interact with the C-terminal portion of the inositol 1,4,5-trisphosphate receptors.	ITPR1 ITPR2	2.46e-05	4	71	2	11163362
Pubmed	IP3R-mediated Ca2+ signaling controls B cell proliferation through metabolic reprogramming.	ITPR1 ITPR2	2.46e-05	4	71	2	35494252
Pubmed	Outer nuclear membrane protein Kuduk modulates the LINC complex and nuclear envelope architecture.	SYNE1 SYNE2	2.46e-05	4	71	2	28716842
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	SLC7A3 DST ANK2 SYNE1 SYNE2 RACGAP1 WDR18 WDR1 DYNC1H1 GOLGB1	2.53e-05	963	71	10	28671696
Pubmed	The c-Ski family member and transcriptional regulator Corl2/Skor2 promotes early differentiation of cerebellar Purkinje cells.	RELN GOLGB1 ITPR1	2.57e-05	28	71	3	24491816
Pubmed	Comprehensive proteomic characterization of stem cell-derived extracellular matrices.	COL12A1 VCAN COL14A1 IFNA2	2.98e-05	86	71	4	28327460
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	RALGAPA1 DST ANK2 SLC24A2 PPFIA4 SYNE1 VCAN USP54 WDR1 UTRN DYNC1H1 ITPR2	3.04e-05	1431	71	12	37142655
Pubmed	InsP₃receptors and Orai channels in pancreatic acinar cells: co-localization and its consequences.	ITPR1 ITPR2	4.09e-05	5	71	2	21568942
Pubmed	Splicing variations in the ligand-binding domain of ApoER2 results in functional differences in the binding properties to Reelin.	RELN ITPR1	4.09e-05	5	71	2	19167437
Pubmed	Disabled-1 acts downstream of Reelin in a signaling pathway that controls laminar organization in the mammalian brain.	RELN VCAN	4.09e-05	5	71	2	9716537
Pubmed	Scrambler and yotari disrupt the disabled gene and produce a reeler-like phenotype in mice.	RELN LEPR	4.09e-05	5	71	2	9338784
Interaction	C1QTNF9 interactions	COL12A1 DST MYOM1 COL14A1 UTRN	1.75e-07	37	70	5	int:C1QTNF9
Interaction	PRC1 interactions	THOC1 UTP18 TCERG1 PLCXD1 PPFIA4 SYNE1 CGAS SNRNP40 RACGAP1 URB2 WDR1 DYNC1H1 GOLGB1 ITPR2	5.25e-06	973	70	14	int:PRC1
Interaction	ACTC1 interactions	GAPVD1 DST TCERG1 SYNE1 SYNE2 SNRNP40 NASP WDR1 UTRN DYNC1H1 GOLGB1	2.54e-05	694	70	11	int:ACTC1
Interaction	TAFA4 interactions	VCAN LEPR ITPR1 ITPR2	3.98e-05	55	70	4	int:TAFA4
Interaction	KIF20A interactions	RALGAPA1 ANK2 SYNE1 SYNE2 CGAS NAV3 SNRNP40 RACGAP1 USP54 WDR1 UTRN ITPR1 ITPR2	5.87e-05	1052	70	13	int:KIF20A
GeneFamily	Inositol 1,4,5-triphosphate receptors\|Protein phosphatase 1 regulatory subunits	ITPR1 ITPR2	2.15e-05	3	49	2	297
GeneFamily	Spectrin repeat containing nuclear envelope family	SYNE1 SYNE2	4.30e-05	4	49	2	1252
GeneFamily	WD repeat domain containing	UTP18 SNRNP40 WDR18 WDR1 SPAG16	6.97e-04	262	49	5	362
GeneFamily	Interferons	IFNA2 IFNA5	3.39e-03	32	49	2	598
GeneFamily	Hyalectan proteoglycans\|V-set domain containing\|Sushi domain containing\|C-type lectin domain containing	VCAN REG1B	5.52e-03	41	49	2	1298
GeneFamily	Forkhead boxes	FOXJ2 FOXP1	6.05e-03	43	49	2	508
GeneFamily	Collagens	COL12A1 COL14A1	6.90e-03	46	49	2	490
GeneFamily	GATA zinc finger domain containing\|Myb/SANT domain containing	GON4L MYSM1	9.08e-03	53	49	2	532
GeneFamily	Fibronectin type III domain containing	COL12A1 MYOM1 COL14A1	9.30e-03	160	49	3	555
Coexpression	GSE14699_NAIVE_VS_DELETIONAL_TOLERANCE_CD8_TCELL_UP	FOXJ2 KIZ SYNE1 FOXP1 DZIP1 ITPR2	3.33e-06	152	70	6	M2938
Coexpression	GSE13547_WT_VS_ZFX_KO_BCELL_ANTI_IGM_STIM_12H_DN	FOXJ2 KIZ FOXP1 DZIP1 IFNA2 ITPR2	4.31e-06	159	70	6	M2983
Coexpression	NABA_MATRISOME	RELN COL12A1 VCAN OGFOD1 MUC16 COL14A1 REG1B HCFC2 MMP20 IFNA2 IFNA5 ITIH5	1.33e-05	1008	70	12	MM17056
Coexpression	GSE22611_NOD2_VS_CTRL_TRANSDUCED_HEK293T_CELL_UP	TCERG1 SYNE2 SNRNP40 RACGAP1 IFNA2 ITPR1	1.47e-05	197	70	6	M8166
Coexpression	NABA_MATRISOME	RELN COL12A1 VCAN OGFOD1 MUC16 COL14A1 REG1B HCFC2 MMP20 IFNA2 IFNA5 ITIH5	1.59e-05	1026	70	12	M5889
Coexpression	GSE11386_NAIVE_VS_MEMORY_BCELL_DN	KCTD19 SYNE1 FOXP1 ALDH6A1 UTRN	6.59e-05	158	70	5	M372
Coexpression	GSE13547_CTRL_VS_ANTI_IGM_STIM_ZFX_KO_BCELL_12H_DN	FOXJ2 KIZ SYNE1 FOXP1 DZIP1	7.42e-05	162	70	5	M7002
Coexpression	GSE14415_INDUCED_TREG_VS_TCONV_DN	FOXJ2 KIZ FOXP1 DZIP1 ITPR2	8.09e-05	165	70	5	M2960
CoexpressionAtlas	DevelopingKidney_e15.5_Pelvic Mesenchyme_emap-8241_k-means-cluster#1_top-relative-expression-ranked_200	VCAN NAV3 COL14A1 MCTP2 LEPR	8.26e-06	86	68	5	gudmap_developingKidney_e15.5_Pelvic Mesenchyme_200_k1
CoexpressionAtlas	DevelopingGonad_e18.5_epididymis_emap-13166_k-means-cluster#3_top-relative-expression-ranked_500	SYNE2 NASP FNIP1 MYSM1	6.33e-05	67	68	4	gudmap_developingGonad_e18.5_epididymis_500_k3
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ Genital tubercle F_emap-6706_top-relative-expression-ranked_1000	DST ANK2 VCAN SOCS4 SYNE2 OGFOD1 COL14A1 FOXP1 DZIP1 HCFC2 LEPR	7.54e-05	850	68	11	gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle F_1000
CoexpressionAtlas	DevelopingGonad_e18.5_ovary_emap-12283_k-means-cluster#3_top-relative-expression-ranked_200	SYNE2 FNIP1 MYSM1	7.75e-05	26	68	3	gudmap_developingGonad_e18.5_ovary_200_k3
CoexpressionAtlas	dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_top-relative-expression-ranked_1000	COL12A1 SLC30A5 VCAN MUC16 COL14A1 MANSC4 DZIP1 ITIH5 ITPR1 ITPR2	1.16e-04	740	68	10	gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_1000
CoexpressionAtlas	DevelopingKidney_e15.5_Peripheral blastema_emap-27731_k-means-cluster#3_top-relative-expression-ranked_500	COL12A1 SOCS4 CGAS LEPR	1.39e-04	82	68	4	gudmap_developingKidney_e15.5_Peripheral blastema_500_k3
CoexpressionAtlas	DevelopingKidney_e15.5_Ureteral Smooth Musc_emap-28812_top-relative-expression-ranked_1000	RALGAPA1 DST MYOM1 SYNE1 VCAN CGAS COL14A1 LEPR ITIH5 ITPR1	1.64e-04	772	68	10	gudmap_developingKidney_e15.5_Ureteral Smooth Musc_1000
CoexpressionAtlas	DevelopingLowerUrinaryTract_P1_bladder_J_emap-30374_top-relative-expression-ranked_200	DST MYOM1 NIPAL1 LEPR ITIH5	1.67e-04	161	68	5	gudmap_developingLowerUrinaryTract_P1_bladder_200_J
CoexpressionAtlas	DevelopingKidney_e15.5_Pelvic Mesenchyme_emap-8241_top-relative-expression-ranked_200	VCAN NAV3 COL14A1 MCTP2 LEPR	1.82e-04	164	68	5	gudmap_developingKidney_e15.5_Pelvic Mesenchyme_200
CoexpressionAtlas	dev gonad_e12.5_F_VasAssMesen_MafB_top-relative-expression-ranked_1000	COL12A1 SLC30A5 VCAN SYNE2 MUC16 ATG4C MANSC4 DZIP1 ITPR1 ITPR2	1.84e-04	783	68	10	gudmap_dev gonad_e12.5_F_VasAssMesen_MafB_1000
CoexpressionAtlas	DevelopingKidney_e15.5_Medullary collecting duct_emap-28063_k-means-cluster#4_top-relative-expression-ranked_1000	RALGAPA1 VCAN GON4L FOXP1 UTRN MYSM1	1.88e-04	261	68	6	gudmap_developingKidney_e15.5_Medullary collecting duct_1000_k4
CoexpressionAtlas	DevelopingGonad_P2_epididymis_emap-30199_top-relative-expression-ranked_1000	GAPVD1 COL12A1 MYOM1 SYNE2 NASP FNIP1 COL14A1 UTRN MYSM1 ITIH5	2.12e-04	797	68	10	gudmap_developingGonad_P2_epididymis_1000
CoexpressionAtlas	DevelopingKidney_e15.5_Ureteral Smooth Musc_emap-28812_k-means-cluster#2_top-relative-expression-ranked_1000	MYOM1 SYNE1 VCAN COL14A1 LEPR ITIH5	2.26e-04	270	68	6	gudmap_developingKidney_e15.5_Ureteral Smooth Musc_1000_k2
CoexpressionAtlas	DevelopingGonad_e14.5_ epididymis_emap-29141_k-means-cluster#3_top-relative-expression-ranked_1000	GAPVD1 SYNE2 NASP FNIP1 UTRN MYSM1	2.50e-04	275	68	6	gudmap_developingGonad_e14.5_ epididymis_1000_k3
CoexpressionAtlas	DevelopingGonad_e18.5_epididymis_emap-13166_top-relative-expression-ranked_500	SYNE2 NASP FNIP1 COL14A1 UTRN MYSM1 ITIH5	3.06e-04	404	68	7	gudmap_developingGonad_e18.5_epididymis_500
CoexpressionAtlas	DevelopingGonad_e14.5_ ovary_emap-6699_k-means-cluster#1_top-relative-expression-ranked_500	SYNE2 NASP FNIP1 MYSM1	3.11e-04	101	68	4	gudmap_developingGonad_e14.5_ ovary_500_k1
CoexpressionAtlas	DevelopingKidney_e15.5_Ureteral Smooth Musc_emap-28812_k-means-cluster#5_top-relative-expression-ranked_500	MYOM1 SYNE1 VCAN COL14A1 LEPR	3.34e-04	187	68	5	gudmap_developingKidney_e15.5_Ureteral Smooth Musc_500_k5
CoexpressionAtlas	DevelopingGonad_e14.5_ epididymis_emap-29141_k-means-cluster#2_top-relative-expression-ranked_500	SYNE2 NASP FNIP1 MYSM1	3.87e-04	107	68	4	gudmap_developingGonad_e14.5_ epididymis_500_k2
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ bladder_emap-6668_top-relative-expression-ranked_500	UBE2K MYOM1 VCAN SOCS4 NIPAL1 COL14A1 DZIP1	3.98e-04	422	68	7	DevelopingLowerUrinaryTract_e14.5_ bladder_emap-6668_500
CoexpressionAtlas	DevelopingKidney_e15.5_Ureteral Smooth Musc_emap-28812_k-means-cluster#4_top-relative-expression-ranked_1000	VCAN CGAS COL14A1 LEPR ITIH5	4.05e-04	195	68	5	gudmap_developingKidney_e15.5_Ureteral Smooth Musc_1000_k4
CoexpressionAtlas	DevelopingGonad_e14.5_ ovary_emap-6699_k-means-cluster#1_top-relative-expression-ranked_200	NASP FNIP1 MYSM1	4.05e-04	45	68	3	gudmap_developingGonad_e14.5_ ovary_200_k1
CoexpressionAtlas	DevelopingKidney_e15.5_Pelvic Mesenchyme_emap-8241_k-means-cluster#5_top-relative-expression-ranked_100	NAV3 MCTP2 LEPR	4.32e-04	46	68	3	gudmap_developingKidney_e15.5_Pelvic Mesenchyme_100_k5
CoexpressionAtlas	DevelopingKidney_e15.5_Pelvic Mesenchyme_emap-8241_k-means-cluster#2_top-relative-expression-ranked_1000	VCAN CGAS NAV3 COL14A1 MCTP2 LEPR	4.33e-04	305	68	6	gudmap_developingKidney_e15.5_Pelvic Mesenchyme_1000_k2
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL12A1 DST ANK2 VCAN NAV3 COL14A1 LEPR	2.71e-08	195	71	7	f54bc4454270ff06e85596f98199372b50d0179f
ToppCell	Tracheal-NucSeq-Stromal-Fibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	COL12A1 ANK2 SYNE1 VCAN NAV3 COL14A1 LEPR	3.23e-08	200	71	7	b4ccffdd79526c85e5273d27b668dbddcddba1ee
ToppCell	Tracheal-NucSeq-Stromal-Fibroblastic-Fibro_adventitial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	COL12A1 ANK2 SYNE1 VCAN NAV3 COL14A1 LEPR	3.23e-08	200	71	7	0c25d56292b9e5fefa4521b72635449be1ffd6fe
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma\|TCGA-Brain / Sample_Type by Project: Shred V9	DST SYNE1 CCSER2 USP54 DYNC1H1 GOLGB1	3.95e-07	177	71	6	e8ab340b20cd41554c3841fe980e078e878af35f
ToppCell	COVID-19-kidney-Epi_(Mes)\|kidney / Disease (COVID-19 only), tissue and cell type	RELN CFAP54 COL12A1 DST SYNE1 VCAN	4.21e-07	179	71	6	e7c9dc63f03d3f3746b51a7e3c8393089e2ceb7d
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	RELN CFAP54 SYNE1 VCAN NAV3 ITIH5	4.50e-07	181	71	6	5f2d3a08577c440c944778d07aa993c6e7873f3d
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	RELN CFAP54 SYNE1 VCAN NAV3 ITIH5	4.50e-07	181	71	6	c7c5f7d4c397b4613c772413a0a679377efffff3
ToppCell	3'-Broncho-tracheal-Epithelial-Neuro-endocrine/ionocytic-ionocyte-Ionocyte-Ionocyte_L.0.7.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ANK2 SYNE2 NAV3 RACGAP1 ITIH5 ITPR2	4.95e-07	184	71	6	a60802e11dcc5f932811260b08a95a32f60f6b19
ToppCell	3'-Broncho-tracheal-Epithelial-Neuro-endocrine/ionocytic-ionocyte\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ANK2 SYNE2 NAV3 RACGAP1 ITIH5 ITPR2	4.95e-07	184	71	6	39c230d32e4259bc784e0edfd9e2884c96898564
ToppCell	3'-Broncho-tracheal-Epithelial-Neuro-endocrine/ionocytic-ionocyte-Ionocyte\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ANK2 SYNE2 NAV3 RACGAP1 ITIH5 ITPR2	4.95e-07	184	71	6	2a2fb691cc9414ef5b06c26239d2da03d6d7e5c2
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	RALGAPA1 SYNE2 UTRN DYNC1H1 GOLGB1 ITPR1	5.62e-07	188	71	6	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	critical-Epithelial-Ionocyte\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	DST ANK2 NAV3 RACGAP1 ITIH5 ITPR2	5.97e-07	190	71	6	05a2c3549b68f49081723bf35db14974274419d5
ToppCell	PND10\|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GAPVD1 DST FOXP1 UTRN GOLGB1 ITIH5	5.97e-07	190	71	6	d67e2814047c8df2ae4b7bc8be9539f5df6ecef2
ToppCell	PSB-critical-LOC-Epithelial-Ionocyte\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	DST ANK2 NAV3 RACGAP1 ITIH5 ITPR2	6.16e-07	191	71	6	8f4637e801554e2343b974fe7794f01dd2151418
ToppCell	Control-Multiplet-Multiplet\|World / Disease state, Lineage and Cell class	ATP13A4 SYNE1 SYNE2 ELF3 USP54 MCTP2	6.35e-07	192	71	6	1bfd022d5b87cf8a5d5069f559339a553a52a0a2
ToppCell	renal_papilla_nuclei-Adult_normal_reference\|renal_papilla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	COL12A1 ANK2 KIZ UTRN ITIH5 ITPR1	6.35e-07	192	71	6	6c106b91e46eabbe686a52a65a9c94ad9cbe9390
ToppCell	human_hepatoblastoma\|World / Sample and Cell Type and Tumor Cluster (all cells)	TCERG1 KIZ VCAN UTRN GOLGB1 ITPR2	6.55e-07	193	71	6	e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCell	IPF-Multiplet-Multiplet\|IPF / Disease state, Lineage and Cell class	CFAP54 SYNE1 SYNE2 ELF3 USP54 SPAG16	6.95e-07	195	71	6	fce0c29574bb7aab181b9c00feb42681e285d1f2
ToppCell	IPF-Multiplet\|IPF / Disease state, Lineage and Cell class	CFAP54 SYNE1 SYNE2 ELF3 USP54 SPAG16	6.95e-07	195	71	6	eacc0449ae6f3ad8002268cd061467684c6fb9a7
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN DST SLC24A2 FNIP1 DYNC1H1 GOLGB1	6.95e-07	195	71	6	3e519cffa6144a62b06124642a14c9ff39b76554
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN DST SLC24A2 FNIP1 DYNC1H1 GOLGB1	6.95e-07	195	71	6	7796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell	LPS_IL1RA_TNF\|World / Treatment groups by lineage, cell group, cell type	SYNE1 VCAN COL14A1 ELF3 UTRN ITIH5	7.38e-07	197	71	6	0a6550dce156fc81f15b1e7830d331ca50d87d06
ToppCell	LPS_IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	ATP13A4 SYNE2 MROH5 ELF3 USP54 UTRN	7.38e-07	197	71	6	b94645d57efe8d9e032bffb8c89af1f425c6421e
ToppCell	LPS_anti-TNF-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	ATP13A4 SYNE2 ELF3 USP54 UTRN GOLGB1	7.38e-07	197	71	6	3d13a4f2e86422900ee2194e8a1fd1cf9750d5d3
ToppCell	mild-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	RALGAPA1 SYNE1 SYNE2 MCTP2 UTRN GOLGB1	7.83e-07	199	71	6	f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCell	ILEUM-inflamed-(8)_Fibroblasts\|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	COL12A1 DST ANK2 VCAN COL14A1 ITIH5	7.83e-07	199	71	6	3a3e2bb21cd0293622b1a975263e918d9ba24265
ToppCell	LPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	DST ANK2 SYNE1 VCAN COL14A1 ITIH5	7.83e-07	199	71	6	30d3e8c0681ec11f86dd38c5f48d21187a1b4f90
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	COL12A1 DST SYNE2 FOXP1 UTRN LEPR	8.06e-07	200	71	6	dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell	LPS_only-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_only / Treatment groups by lineage, cell group, cell type	ATP13A4 SYNE2 ELF3 USP54 UTRN GOLGB1	8.06e-07	200	71	6	2dadf317a42a7e27cc1fac74f91b806c93a57108
ToppCell	Tracheal-NucSeq-Stromal-Fibroblastic-Fibro_perichondrial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	COL12A1 ANK2 SYNE1 VCAN COL14A1 LEPR	8.06e-07	200	71	6	a4ec0e80f5422b91b85264a9bb74568dd577e285
ToppCell	LPS_IL1RA_TNF-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	ATP13A4 SYNE2 ELF3 USP54 UTRN GOLGB1	8.06e-07	200	71	6	ddfb1f006365bf16203ee49f20200f68220cc288
ToppCell	Skin-Fibroblasts\|Skin / Skin and Kidney Cells in Lupus Nephritis Patients.	COL12A1 ANK2 VCAN COL14A1 LEPR ITIH5	8.06e-07	200	71	6	f777eadf571a1a6d246da87346a9cb9d511c2e81
ToppCell	Tracheal-NucSeq-Stromal-Fibroblastic-Fibro_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SYNE1 VCAN NAV3 COL14A1 LEPR ITIH5	8.06e-07	200	71	6	3dd022e974fec7013ba18f333da63f58fbf2dd7c
ToppCell	Control_saline-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|Control_saline / Treatment groups by lineage, cell group, cell type	DST ANK2 SYNE1 VCAN COL14A1 ITIH5	8.06e-07	200	71	6	bd8cf33502adea320e91ca2af14e1911d88ad374
ToppCell	3'_v3-blood-Lymphocytic_T_CD4-T_CD4/CD8\|blood / Manually curated celltypes from each tissue	SYNE1 SYNE2 COL14A1 UTRN GOLGB1	2.51e-06	135	71	5	ae2d3a42e567b5bade304c0caa497eb725be3565
ToppCell	3'-Distal_airway-Epithelial-Neuro-endocrine/ionocytic-ionocyte\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ANK2 NAV3 RACGAP1 ITIH5 ITPR2	6.11e-06	162	71	5	9a18286e361e1dd18e6f943ce27db58b199fb6e4
ToppCell	3'-Distal_airway-Epithelial-Neuro-endocrine/ionocytic-ionocyte-Ionocyte-Ionocyte_L.0.7.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ANK2 NAV3 RACGAP1 ITIH5 ITPR2	6.11e-06	162	71	5	3395e4dffdb9304d157c325e1fc0f12b433c7bd3
ToppCell	3'-Distal_airway-Epithelial-Neuro-endocrine/ionocytic-ionocyte-Ionocyte\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ANK2 NAV3 RACGAP1 ITIH5 ITPR2	6.11e-06	162	71	5	9522af31f6b2f3cb81b6b84bd08353eea504d1d6
ToppCell	10x5'-blood-Lymphocytic_T_CD4-T_CD4/CD8\|blood / Manually curated celltypes from each tissue	RALGAPA1 SYNE2 FOXP1 UTRN ITPR1	6.11e-06	162	71	5	b4535bcb3f469bc139e73f1122f4070013e5a1de
ToppCell	3'-Distal_airway-Epithelial-Neuro-endocrine/ionocytic\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ANK2 NAV3 RACGAP1 ITIH5 ITPR2	6.11e-06	162	71	5	40265af9b36fd144a8577b8dacccd4fc0888a593
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	RALGAPA1 SYNE1 SYNE2 UTRN GOLGB1	7.95e-06	171	71	5	2e9a20f8980b78325c52065a9c14ab3656267c05
ToppCell	Bronchial_Brush-Epithelial-Ionocytes\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	ANK2 NAV3 RACGAP1 ITIH5 ITPR2	8.41e-06	173	71	5	e1de849dcd96063136bdac87e050ddbd55cabdcc
ToppCell	Bronchial_Brush-Epithelial-Ionocytes\|Bronchial_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X	ANK2 NAV3 RACGAP1 ITIH5 ITPR2	8.41e-06	173	71	5	f2a8f4918c1fb68d98bc3f33cd624de0f0f11e06
ToppCell	Bronchial_Biopsy-Epithelial-Ionocytes\|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X	ANK2 NAV3 RACGAP1 ITIH5 ITPR2	8.65e-06	174	71	5	7e7b13de916cd4fa0fa6fb06e6b4942877afa9fb
ToppCell	Bronchial_Biopsy-Epithelial-Ionocytes\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	ANK2 NAV3 RACGAP1 ITIH5 ITPR2	8.89e-06	175	71	5	13b8f7dc38c90b74d4a20a84a8705d8e2ec244f6
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	RACGAP1 FOXP1 ITIH5 ITPR1 ITPR2	8.89e-06	175	71	5	77c16e615c0fb9c83f29d7e0a547be72635fac81
ToppCell	NS-moderate-d_0-4-Epithelial-Ionocyte\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	DST ANK2 NAV3 ITIH5 ITPR2	8.89e-06	175	71	5	a1e0a15c69211d6db2edeb101476f0f6e08b90c8
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ATP13A4 CFAP54 SYNE1 MCTP2 UTRN	9.14e-06	176	71	5	327a3e81b724252e36d786de92a3ffd721ea6d7b
ToppCell	NS-critical-d_0-4-Epithelial-Ionocyte\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	DST ANK2 URB2 ITIH5 ITPR2	1.05e-05	181	71	5	cfc3ed541d93158ce26641ea30b7573d93600a11
ToppCell	5'-Airway_Nasal-Epithelial-Neuro-endocrine/ionocytic-ionocyte-Ionocyte-Ionocyte_L.0.7.0.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DST ANK2 NAV3 ITIH5 ITPR2	1.05e-05	181	71	5	40df0afcb6848202da54670e84f22d7c3a515d01
ToppCell	COVID-19-Epithelial-Ionocytes\|Epithelial / Condition, Lineage and Cell class	ANK2 RACGAP1 URB2 ITIH5 ITPR2	1.05e-05	181	71	5	4a8d4f2709c1b25f908867f1b2fae1d2d0abf1d4
ToppCell	5'-Airway_Nasal-Epithelial-Neuro-endocrine/ionocytic-ionocyte-Ionocyte\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DST ANK2 NAV3 ITIH5 ITPR2	1.05e-05	181	71	5	2b53a65ca5616a7b9f64232c3e0b7212d1e2f063
ToppCell	5'-Airway_Nasal-Epithelial-Neuro-endocrine/ionocytic-ionocyte\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DST ANK2 NAV3 ITIH5 ITPR2	1.05e-05	181	71	5	6aef84616e8d2faf54b7e9e6cd02f33c3066dabc
ToppCell	5'-Airway_Nasal-Epithelial-Neuro-endocrine/ionocytic\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DST ANK2 NAV3 ITIH5 ITPR2	1.05e-05	181	71	5	40d3829ae4aaf81e8616c3499ff8933137fc1cc4
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL12A1 VCAN NAV3 COL14A1 ITIH5	1.08e-05	182	71	5	3dfa9187e9d2bab1d199079d29209c4648220ada
ToppCell	PND01-03-samps-Mesenchymal-Myofibroblast\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	COL12A1 DST ANK2 VCAN ITIH5	1.08e-05	182	71	5	812dac35b9aa05be48258082e007f6c00e7b4dd8
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATP13A4 RELN COL12A1 SLC24A2 NAV3	1.13e-05	184	71	5	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	LPS_only-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ATP13A4 SYNE2 ELF3 USP54 UTRN	1.13e-05	184	71	5	42ce855b4f8475a8298192feec785bdc69bc5bb0
ToppCell	TCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-4\|TCGA-Pancreas / Sample_Type by Project: Shred V9	NAV3 COL14A1 UTRN LEPR ITPR2	1.13e-05	184	71	5	67164bb6bcae7322cb89b585c7aa10bce35b0ecd
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATP13A4 RELN COL12A1 SLC24A2 NAV3	1.13e-05	184	71	5	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATP13A4 RELN COL12A1 SLC24A2 NAV3	1.13e-05	184	71	5	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	RELN CFAP54 SYNE1 MCTP2 ITIH5	1.16e-05	185	71	5	34fcfd635c828dad9643bbf1c908d79282d6f5d9
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	RELN CFAP54 SYNE1 MCTP2 ITIH5	1.16e-05	185	71	5	8816f2909ed11833ff3d0ed96b9cb6d6fe9e1578
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CFAP54 SYNE1 SYNE2 COL14A1 SPAG16	1.19e-05	186	71	5	f0c8de4f6ae9047b9108a47a2af8c5f42bc103b0
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ANK2 CCDC178 DZIP1 ITPR1 ITPR2	1.23e-05	187	71	5	b93cf4dfe8ffb89348ee7bccc9f284189f7240a2
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ATP13A4 SYNE2 ELF3 USP54 UTRN	1.23e-05	187	71	5	58d48128547ee3513d0bf7f78e61b76b1c472ca9
ToppCell	Control-Fibroblasts-Adventitial_FB\|Control / group, cell type (main and fine annotations)	ANK2 VCAN NAV3 COL14A1 LEPR	1.26e-05	188	71	5	706a26c372add839d947749f0521a0e1f5c9b0ec
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ATP13A4 CFAP54 SYNE1 MCTP2 UTRN	1.26e-05	188	71	5	63a4b25a0a6e05f80f1a6dd91b817f3cf49e6b68
ToppCell	facs-Pancreas-Endocrine-24m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN DST ANK2 SLC24A2 GOLGB1	1.26e-05	188	71	5	a91443aa8fa8fa87f7501c59219daa0305bd0bbf
ToppCell	PND07-28-samps-Mesenchymal-Myofibroblast\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	COL12A1 ANK2 COL14A1 DZIP1 ITIH5	1.36e-05	191	71	5	9bbafdf316c1fa3a9f1ee30d41dd7158b5c97279
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DST VCAN COL14A1 MCTP2 ITPR1	1.36e-05	191	71	5	c54c420a94dc749ebc67fc64c5614663f4b9798d
ToppCell	E18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL12A1 VCAN COL14A1 LEPR ITIH5	1.36e-05	191	71	5	4b50fdd310701251e64e16cd2d07ce03dbfd3e3e
ToppCell	facs-Pancreas-Endocrine-24m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN DST ANK2 SLC24A2 GOLGB1	1.36e-05	191	71	5	3387b95a3f2445c672d407922fdce3a91eabaef8
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DST VCAN COL14A1 MCTP2 ITPR1	1.36e-05	191	71	5	806b94f567ea09a9f443cd4091e70cdb1253ac08
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DST VCAN COL14A1 MCTP2 ITPR1	1.36e-05	191	71	5	cb0aee740b08f7d5fdd2717ecf7429043b277ae7
ToppCell	E18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL12A1 VCAN COL14A1 LEPR ITIH5	1.36e-05	191	71	5	75d2197076a9dfc868e8baf95bd4c5e44f438e3e
ToppCell	human_hepatoblastoma-Tumor_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	TCERG1 KIZ VCAN UTRN ITPR2	1.39e-05	192	71	5	916fbec1c7ab7969bda711886ac88e877e30c280
ToppCell	COPD-Lymphoid\|COPD / Disease state, Lineage and Cell class	RALGAPA1 SYNE1 SYNE2 CCSER2 MCTP2	1.39e-05	192	71	5	064fefb8212fadab0ff441f4bf643559b7fdb25d
ToppCell	PCW_07-8.5-Epithelial-Epithelial_neuroendo-epi_NE_progenitor_(7)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	ATP13A4 CFAP54 ANK2 ELF3 MCTP2	1.39e-05	192	71	5	b99f8236ef4ccdc75c02abea381cae6453205f6f
ToppCell	10x_3'_v3-thymus_(10x_3'_v3)-lymphocytic-T_lymphocytic-CD8-positive,_alpha-beta_T_cell\|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	SYNE1 SYNE2 CCSER2 UTRN MYSM1	1.43e-05	193	71	5	a594f89a18273797506287d9e22f72abe53e4920
ToppCell	Control-Multiplet\|Control / Disease state, Lineage and Cell class	ATP13A4 SYNE1 SYNE2 ELF3 USP54	1.50e-05	195	71	5	618900c80bea09d46dad3f741bd1bff8bf0a64ee
ToppCell	ASK428-Mesenchymal\|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq	ANK2 VCAN NAV3 COL14A1 ITIH5	1.50e-05	195	71	5	2b156163975d9a3d3fda1402acd9831d0fdc9e25
ToppCell	Control-Multiplet-Multiplet\|Control / Disease state, Lineage and Cell class	ATP13A4 SYNE1 SYNE2 ELF3 USP54	1.50e-05	195	71	5	06ac685855e14e4dd2cbe6d0e73f894f2eeff91f
ToppCell	ASK428-Mesenchymal-Fibroblast\|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq	ANK2 VCAN NAV3 COL14A1 ITIH5	1.50e-05	195	71	5	c269c0d894a0f55da6495b59d4b9abb9f68df684
ToppCell	10x_5'_v1-Non-neoplastic-Lymphoid-CD4/CD8-Stress_sig-F_2\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SYNE1 SYNE2 CGAS CCSER2 UTRN	1.54e-05	196	71	5	ea8eceacc5d5e1a22b77c31e7c45985dc7bb15de
ToppCell	COPD-Multiplet-Multiplet\|COPD / Disease state, Lineage and Cell class	CFAP54 SYNE1 SYNE2 ELF3 MCTP2	1.54e-05	196	71	5	af4cdc61830685a888a1209826c23bcf54a43084
ToppCell	COPD-Multiplet\|COPD / Disease state, Lineage and Cell class	CFAP54 SYNE1 SYNE2 ELF3 MCTP2	1.54e-05	196	71	5	6d02d494196e3f857d53eea46d9419690d43beca
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-PFC\|World / Primary Cells by Cluster	VCAN SYNE2 CCSER2 DYNC1H1 ITPR2	1.58e-05	197	71	5	2c3b0072f8e1e09c77a85c6fc3133d1796932fb2
ToppCell	Control_saline-Epithelial_alveolar-AT_2-Differentiating_AT2\|Control_saline / Treatment groups by lineage, cell group, cell type	ATP13A4 PLCXD1 ELF3 USP54 UTRN	1.58e-05	197	71	5	44a59dfb889577b3160a5b13ada1276771a00241
ToppCell	COVID-19-Fibroblasts-Intermediate_pathological_FB\|COVID-19 / group, cell type (main and fine annotations)	COL12A1 DST VCAN NAV3 COL14A1	1.58e-05	197	71	5	f1c8936986123a3151140c374fcd62d6705c530b
ToppCell	3'-GW_trimst-2-LargeIntestine-Mesenchymal-immature_mesenchymal_cell\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL12A1 SYNE1 VCAN COL14A1 ITIH5	1.58e-05	197	71	5	9af431323da6d099459b7360af40e5df998cffbd
ToppCell	LPS_only-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS_only / Treatment groups by lineage, cell group, cell type	PLCXD1 SYNE2 ELF3 USP54 GOLGB1	1.58e-05	197	71	5	1a1bee8da6e04b65935c40373eaee4d6c046d9a1
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-PFC-29\|World / Primary Cells by Cluster	VCAN SYNE2 CCSER2 DYNC1H1 ITPR2	1.58e-05	197	71	5	c5bc0e7eb85642b270efc2ba92b13a736af22052
ToppCell	Control_saline-Epithelial_alveolar-AT_1-Differentiating_AT1\|Control_saline / Treatment groups by lineage, cell group, cell type	ATP13A4 SYNE2 ELF3 UTRN GOLGB1	1.61e-05	198	71	5	85f424cd9bb3117c9e322031024aabb87696ce47
ToppCell	3'-GW_trimst-2-LargeIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_2_(ZEB2+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL12A1 SYNE1 VCAN COL14A1 ITIH5	1.61e-05	198	71	5	a883e25cb7a78b2ecfb15cef4633bdd02dfafb12
ToppCell	COVID-19-lung-Fibroblast\|lung / Disease (COVID-19 only), tissue and cell type	DST ANK2 VCAN NAV3 COL14A1	1.61e-05	198	71	5	df3de77216f5c5d6141ec44d01c56b942f611838
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-immature_mesenchymal_cell\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL12A1 VCAN SYNE2 COL14A1 ITIH5	1.65e-05	199	71	5	01ab0363558f215f9979e20fd5170d8fee149cea
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	RELN COL12A1 SYNE1 VCAN ITIH5	1.65e-05	199	71	5	b9338b739162cd8e5661c9a4dcb41a31219b5723
ToppCell	10x5'v1-week_14-16-Mesenchymal_adipo-stroma\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	COL12A1 ANK2 VCAN COL14A1 LEPR	1.65e-05	199	71	5	9b2262edbdec89166d895ab97527e0ee5f9b6010
ToppCell	LPS_anti-TNF-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	ATP13A4 SYNE2 ELF3 UTRN GOLGB1	1.65e-05	199	71	5	d43c605a4ff221cf78d91678c15d2ad20f831c7f
Computational	Genes upregulated in subsets of cells of a given type within various tumors	SYNE1 SYNE2 UTRN DYNC1H1 GOLGB1	1.52e-06	49	44	5	GAVISH_3CA_METAPROGRAM_CD8_T_CELLS_CHROMATIN
Computational	Genes upregulated in subsets of cells of a given type within various tumors	COL12A1 DST SYNE1 DYNC1H1 GOLGB1	1.68e-06	50	44	5	GAVISH_3CA_METAPROGRAM_FIBROBLASTS_CAF_4
Disease	Anoxic Encephalopathy	ITPR1 ITPR2	5.71e-06	2	71	2	C0003132
Disease	Brain Hypoxia	ITPR1 ITPR2	5.71e-06	2	71	2	C1527348
Disease	Anoxia of brain	ITPR1 ITPR2	5.71e-06	2	71	2	C0995195
Disease	Hypoxic Brain Damage	ITPR1 ITPR2	5.71e-06	2	71	2	C1140716
Disease	Autosomal dominant Emery-Dreifuss muscular dystrophy	SYNE1 SYNE2	3.41e-05	4	71	2	cv:CN293514
Disease	serum iron measurement	ATP13A4 SLC24A2 LEPR MYSM1	5.63e-05	86	71	4	EFO_0006332
Disease	Autosomal Recessive Emery-Dreifuss Muscular Dystrophy	SYNE1 SYNE2	5.68e-05	5	71	2	C1450051
Disease	diacylglycerol 44:6 measurement	SYNE2 BUD13	5.68e-05	5	71	2	EFO_0020070
Disease	Autosomal Dominant Emery-Dreifuss Muscular Dystrophy (disorder)	SYNE1 SYNE2	5.68e-05	5	71	2	C0410190
Disease	Emery-Dreifuss muscular dystrophy	SYNE1 SYNE2	8.51e-05	6	71	2	cv:C0410189
Disease	Muscular Dystrophy, Emery-Dreifuss	SYNE1 SYNE2	8.51e-05	6	71	2	C0410189
Disease	X-Linked Emery-Dreifuss Muscular Dystrophy	SYNE1 SYNE2	1.19e-04	7	71	2	C0751337
Disease	matrix metalloproteinase 7 measurement	ELF3 MMP20	1.58e-04	8	71	2	EFO_0010591
Disease	atrial fibrillation	SLC24A2 PPFIA4 SYNE2 HCFC2 WDR1 ITPR2	2.73e-04	371	71	6	EFO_0000275
Disease	autosomal dominant cerebellar ataxia (implicated_via_orthology)	ITPR1 ITPR2	3.71e-04	12	71	2	DOID:1441 (implicated_via_orthology)
Disease	Emery-Dreifuss muscular dystrophy (implicated_via_orthology)	SYNE1 SYNE2	3.71e-04	12	71	2	DOID:11726 (implicated_via_orthology)
Disease	Renal Insufficiency	IFNA2 LEPR	7.58e-04	17	71	2	C1565489
Disease	response to anticonvulsant	ANK2 NAV3 LEPR	1.14e-03	85	71	3	GO_0036277
Disease	amino acid measurement	SYNE1 VCAN NAV3 BUD13 COL14A1 MMP20 MCTP2	1.22e-03	678	71	7	EFO_0005134
Disease	Kidney Failure	IFNA2 LEPR	1.28e-03	22	71	2	C0035078
Disease	Hodgkin Disease	RELN IFNA2	1.28e-03	22	71	2	C0019829
Disease	uterine fibroid	SLC7A3 SYNE1 NIPAL1 ITPR1	1.37e-03	199	71	4	EFO_0000731
Disease	Immunologic Deficiency Syndromes	LEPR MYSM1	1.40e-03	23	71	2	C0021051
Disease	Neurodevelopmental Disorders	ANK2 FOXP1 ITPR1	1.48e-03	93	71	3	C1535926
Disease	Pancreatic Neoplasm	FOXP1 IFNA2 IFNA5	1.83e-03	100	71	3	C0030297
Disease	gastroesophageal reflux disease	VCAN NAV3 FOXP1	1.88e-03	101	71	3	EFO_0003948
Disease	Malignant neoplasm of pancreas	FOXP1 IFNA2 IFNA5	1.93e-03	102	71	3	C0346647
Disease	Thrombocytopenia	WDR1 IFNA2	2.22e-03	29	71	2	C0040034
Disease	complement factor H-related protein 2 measurement	COL12A1 REG1B	2.22e-03	29	71	2	EFO_0600055

Protein segments in the cluster

Peptide	Gene	Start	Entry
TSCWFETSITTEKEL	nan	31	Q9Y3F1
QEEQSKALSTSDWTT	URB2	341	Q14146
KALSTSDWTTELLVV	URB2	346	Q14146
IVDDDVSWTAISTTK	BUD13	51	Q9BRD0
VSWTAISTTKLEKEE	BUD13	56	Q9BRD0
LLIFEKDATSTSSWE	CFAP54	856	Q96N23
TETTESLEVTWKPET	VCAN	1471	P13611
SSSASISWTLVEEKK	ATP13A4	751	Q4VNC1
SSSDELSWIIELLEK	ELF3	131	P78545
ISVDITLALESKSSW	CGAS	316	Q8N884
IENSDSESWTSHTVK	ATG4C	141	Q96DT6
SATSATSSKALWEIE	ITPR2	271	Q14571
DSLLWKEASALTSSE	KCTD19	36	Q17RG1
LEKTDILSVRTWTSD	ARHGEF19	736	Q8IW93
SKVIITKTDVDSDSW	ANK2	3031	Q01484
TKTDVDSDSWSEIRE	ANK2	3036	Q01484
WLSDISKIDLESTID	OGFOD1	126	Q8N543
TITSQWKEEDATLSS	ALDH6A1	511	Q02252
WLEETSADTLIGEST	MUC16	581	Q8WXI7
LDTTEWTTLVSDSQE	HCFC2	291	Q9Y5Z7
SSSSSLKQSEEELDW	MCTP2	91	Q6DN12
TTKELLSSWLQSDDE	ITIH5	581	Q86UX2
SATSATSSKALWEVE	ITPR1	271	Q14643
KEISDDITSDITSWE	DST	2936	Q03001
LETSTKTDSEEGSWA	PPFIA4	921	O75335
DISETVSETWSTDVL	GAPVD1	646	Q14C86
TISETTSEAWSVEVL	GAPVD1	706	Q14C86
FEEWSRTSSTKDLKE	CCDC178	121	Q5BJE1
RTSSTKDLKEDWSVT	CCDC178	126	Q5BJE1
TDSEKRSTTDETWDS	NAV3	926	Q8IVL0
FSTKDSSATWDETLL	IFNA5	91	P01569
LWKEVTSAHTAEETT	FOXP1	231	Q9H334
TSANEDEVSVTSKTW	MANSC4	271	A6NHS7
DEVSVTSKTWLVSVA	MANSC4	276	A6NHS7
STSDVTDKLTIDWTY	MPZL3	56	Q6UWV2
ETISEDISVDTSWKN	LEPR	916	P48357
MASDLESSLTSIDWL	FOXJ2	1	Q9P0K8
EEEEESWSTSSDLTI	KIZ	366	Q2M2Z5
TTALVEDTLTEISEW	PLCXD1	126	Q9NUJ7
LTLDWLTETSEEAKG	NASP	201	P49321
TVLEDDFTTLDSRKW	RELN	2321	P78509
SKTDEWIDISVSDRS	CCSER2	461	Q9H7U1
LDWRVDIKTSSDSIS	COMMD9	126	Q9P000
VTDETTDSFKITWTQ	COL12A1	731	Q99715
ETTSSLRVKWDISDS	COL14A1	746	Q05707
STEETWQSEKLLDSD	FNIP1	701	Q8TF40
SDQVKDLSSVSLSWD	GON4L	36	Q3T8J9
STKDSSAAWDETLLD	IFNA2	91	P01563
ESRTTDLLTDWEKTK	DYNC1H1	1251	Q14204
STLWASKESSLDLSA	CCDC201	86	A0A1B0GTI1
EEAITTESEKLTLWG	SLC7A3	446	Q8WY07
DITWSELTSTAKKEA	NIPAL1	361	Q6NVV3
SLIKESSTDDSNVWI	REG1B	86	P48304
TEKEDVVSVVKSSSW	MMP20	466	O60882
SDVLEETWEKTFTRL	MROH5	156	Q6ZUA9
WAETTKRKTSSDDES	UTP18	196	Q9Y5J1
TKEEWVKHTSISESS	UTRN	816	P46939
KEAASLSEWLSATET	UTRN	1551	P46939
KDRSSTTSTWELLDQ	CARS2	541	Q9HA77
EADELDSWLLSTKAT	SYNE1	6091	Q8NF91
SDLLKSTEAWIENTS	SYNE2	3791	Q8WXH0
STTITSLEKWCLDES	SLC24A2	6	Q9UI40
SASTDKTVAVWDSET	SNRNP40	126	Q96DI7
SKSDEWVSTDLSQTE	SOCS4	156	Q8WXH5
TSSLDQTVKLWEVSS	WDR18	191	Q9BV38
VTTSHDASVKEWTIT	WDR1	591	O75083
TDESLDWDSSLVKTF	RACGAP1	161	Q9H0H5
LKSSLVTVTDWSDTS	DZIP1	851	Q86YF9
EELATEWSLTMETLT	RALGAPA1	656	Q6GYQ0
DETSAITLTSTWKEV	TCERG1	966	O14776
VASSSLDKTSKIWDV	SPAG16	451	Q8N0X2
RTESEESSKDWQSSV	TMEM102	176	Q8N9M5
VALSSKSWDVETATE	UBE2K	181	P61086
LSVTTESKVESWFSL	SLC30A5	256	Q8TAD4
TDEQSLWIEDTTKSV	THOC1	346	Q96FV9
HSRDWEIESTSSESK	USP54	551	Q70EL1
ESLKSSKIAESTEWQ	GOLGB1	1591	Q14789
TDTSVVVSWEESKDA	MYOM1	751	P52179
DETLSSSEITLWTEK	MYSM1	286	Q5VVJ2