Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionATP-dependent diacylglycerol kinase activity

DGKB DGKG DGKZ DGKE DGKH DGKI

7.35e-12111036GO:0004143
GeneOntologyMolecularFunctionlipid kinase activity

DGKB DGKG DGKZ DGKE DGKH DGKI

6.32e-08411036GO:0001727
GeneOntologyMolecularFunctionserine-type peptidase activity

RELN KLK12 OVCH1 F12 TMPRSS11B MST1 KLK8 PLAT MST1L

1.26e-062071039GO:0008236
GeneOntologyMolecularFunctionserine hydrolase activity

RELN KLK12 OVCH1 F12 TMPRSS11B MST1 KLK8 PLAT MST1L

1.53e-062121039GO:0017171
GeneOntologyMolecularFunctionserine-type endopeptidase activity

KLK12 OVCH1 F12 TMPRSS11B MST1 KLK8 PLAT MST1L

6.37e-061901038GO:0004252
GeneOntologyMolecularFunctionglycerol-3-phosphate dehydrogenase [NAD(P)+] activity

GPD1 GPD1L

2.64e-0521032GO:0047952
GeneOntologyMolecularFunctionsulfate adenylyltransferase (ATP) activity

PAPSS2 PAPSS1

2.64e-0521032GO:0004781
GeneOntologyMolecularFunctionsulfate adenylyltransferase activity

PAPSS2 PAPSS1

2.64e-0521032GO:0004779
GeneOntologyMolecularFunctionprenylcysteine oxidase activity

PCYOX1L PCYOX1

2.64e-0521032GO:0001735
GeneOntologyMolecularFunctionglycerol-3-phosphate dehydrogenase (NAD+) activity

GPD1 GPD1L

2.64e-0521032GO:0141152
GeneOntologyMolecularFunctionadenylylsulfate kinase activity

PAPSS2 PAPSS1

2.64e-0521032GO:0004020
GeneOntologyMolecularFunctionphosphotransferase activity, alcohol group as acceptor

DGKB DGKG DGKZ DGKE DGKH ALPK1 PAPSS2 PAPSS1 PANK1 PRKD3 MST1 DGKI MST1L

7.23e-0570910313GO:0016773
GeneOntologyMolecularFunctionkinase activity

DGKB DGKG DGKZ DGKE DGKH ALPK1 PAPSS2 PAPSS1 PANK1 PRKD3 MST1 DGKI MST1L

1.52e-0476410313GO:0016301
GeneOntologyMolecularFunctionDNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity

TOP2A TOP2B

1.57e-0441032GO:0003918
GeneOntologyMolecularFunctiontransferase activity, transferring phosphorus-containing groups

TUT7 DGKB DGKG DGKZ DGKE DGKH ALPK1 PAPSS2 PAPSS1 PANK1 PRKD3 MST1 DGKI MST1L

3.24e-0493810314GO:0016772
GeneOntologyMolecularFunctionendopeptidase activity

KLK12 OVCH1 F12 TMPRSS11B CAPN10 MST1 KLK8 PLAT MST1L

3.85e-044301039GO:0004175
GeneOntologyMolecularFunctionalpha-ketoglutarate transmembrane transporter activity

SLC25A21 SLC13A3

3.90e-0461032GO:0015139
GeneOntologyMolecularFunctionpeptidase activity

RELN UFSP2 KLK12 OVCH1 F12 TMPRSS11B CAPN10 MST1 KLK8 PLAT MST1L

5.56e-0465410311GO:0008233
GeneOntologyMolecularFunctionDNA topoisomerase activity

TOP2A TOP2B

7.23e-0481032GO:0003916
GeneOntologyMolecularFunctionoxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor

PCYOX1L PCYOX1

1.41e-03111032GO:0016670
GeneOntologyBiologicalProcesslipid phosphorylation

DGKB DGKG DGKZ DGKE DGKH DGKI

6.43e-12111046GO:0046834
GeneOntologyBiologicalProcessdiacylglycerol metabolic process

DGKB DGKG DGKZ DGKE DGKH DGKI

4.89e-09281046GO:0046339
GeneOntologyBiologicalProcessphosphatidic acid biosynthetic process

DGKB DGKG DGKZ DGKE DGKH DGKI

2.45e-08361046GO:0006654
GeneOntologyBiologicalProcessphosphatidic acid metabolic process

DGKB DGKG DGKZ DGKE DGKH DGKI

5.53e-08411046GO:0046473
GeneOntologyBiologicalProcessblood coagulation

COMP DGKB DGKG DGKZ DGKE DGKH PAPSS2 F12 DGKI PLAT

7.86e-0726010410GO:0007596
GeneOntologyBiologicalProcesscoagulation

COMP DGKB DGKG DGKZ DGKE DGKH PAPSS2 F12 DGKI PLAT

9.68e-0726610410GO:0050817
GeneOntologyBiologicalProcesshemostasis

COMP DGKB DGKG DGKZ DGKE DGKH PAPSS2 F12 DGKI PLAT

1.04e-0626810410GO:0007599
GeneOntologyBiologicalProcessacylglycerol metabolic process

DGKB DGKG DGKZ DGKE DGKH APOBR DGKI

1.42e-051561047GO:0006639
GeneOntologyBiologicalProcessneutral lipid metabolic process

DGKB DGKG DGKZ DGKE DGKH APOBR DGKI

1.54e-051581047GO:0006638
GeneOntologyBiologicalProcessplatelet activation

COMP DGKB DGKG DGKZ DGKE DGKH DGKI

1.54e-051581047GO:0030168
GeneOntologyBiologicalProcessprenylcysteine metabolic process

PCYOX1L PCYOX1

2.52e-0521042GO:0030329
GeneOntologyBiologicalProcessprenylcysteine catabolic process

PCYOX1L PCYOX1

2.52e-0521042GO:0030328
GeneOntologyBiologicalProcess3'-phosphoadenosine 5'-phosphosulfate biosynthetic process

PAPSS2 PAPSS1

2.52e-0521042GO:0050428
GeneOntologyBiologicalProcesspositive regulation of single stranded viral RNA replication via double stranded DNA intermediate

TOP2A TOP2B

2.52e-0521042GO:0045870
GeneOntologyBiologicalProcesspurine ribonucleoside bisphosphate biosynthetic process

PAPSS2 PAPSS1

2.52e-0521042GO:0034036
GeneOntologyBiologicalProcessglycerol-3-phosphate catabolic process

GPD1 GPD1L

2.52e-0521042GO:0046168
GeneOntologyBiologicalProcessprenylated protein catabolic process

PCYOX1L PCYOX1

7.53e-0531042GO:0030327
GeneOntologyBiologicalProcessregulation of body fluid levels

COMP DGKB DGKG DGKZ DGKE DGKH PAPSS2 F12 DGKI PLAT

8.00e-0544210410GO:0050878
GeneOntologyBiologicalProcessCOPII-coated vesicle cargo loading

SCAP SEC23B SEC23A

9.62e-05181043GO:0090110
GeneOntologyBiologicalProcesslipid modification

DGKB DGKG DGKZ DGKE DGKH GBA2 DGKI

1.06e-042141047GO:0030258
GeneOntologyBiologicalProcessresponse to wounding

COMP DGKB DGKG DGKZ DGKE DGKH MDK PAPSS2 F12 KLK8 DGKI PLAT

1.21e-0465910412GO:0009611
GeneOntologyBiologicalProcesssulfate assimilation

PAPSS2 PAPSS1

1.50e-0441042GO:0000103
GeneOntologyBiologicalProcesswound healing

COMP DGKB DGKG DGKZ DGKE DGKH PAPSS2 F12 DGKI PLAT

1.95e-0449310410GO:0042060
GeneOntologyBiologicalProcessnegative regulation of protein kinase C signaling

DGKG GPD1L

2.49e-0451042GO:0090038
GeneOntologyBiologicalProcessglycerolipid metabolic process

GPD1 DGKB DGKG DGKZ DGKE DGKH APOBR DGKI SERAC1

3.22e-044291049GO:0046486
GeneOntologyBiologicalProcess9-cis-retinoic acid biosynthetic process

ALDH8A1 DHRS9

3.73e-0461042GO:0042904
GeneOntologyBiologicalProcess9-cis-retinoic acid metabolic process

ALDH8A1 DHRS9

3.73e-0461042GO:0042905
GeneOntologyBiologicalProcessorganophosphate biosynthetic process

GPD1 DGKB DGKG DGKZ DGKE DGKH PAPSS2 PAPSS1 PANK1 DGKI SERAC1

4.06e-0464410411GO:0090407
GeneOntologyBiologicalProcessphospholipid biosynthetic process

DGKB DGKG DGKZ DGKE DGKH DGKI SERAC1

4.20e-042681047GO:0008654
GeneOntologyBiologicalProcessalpha-ketoglutarate transport

SLC25A21 SLC13A3

5.20e-0471042GO:0015742
GeneOntologyBiologicalProcesslysine catabolic process

SLC25A21 PIPOX

5.20e-0471042GO:0006554
GeneOntologyBiologicalProcessNADH oxidation

GPD1 GPD1L

5.20e-0471042GO:0006116
GeneOntologyBiologicalProcesslysine metabolic process

SLC25A21 PIPOX

6.91e-0481042GO:0006553
GeneOntologyBiologicalProcessvesicle cargo loading

SCAP SEC23B SEC23A

7.88e-04361043GO:0035459
GeneOntologyBiologicalProcessglycerophospholipid biosynthetic process

DGKB DGKG DGKZ DGKE DGKH DGKI

8.15e-042171046GO:0046474
GeneOntologyBiologicalProcessregulation of macrophage chemotaxis

MDK MST1 MST1L

8.54e-04371043GO:0010758
GeneOntologyBiologicalProcesspositive regulation of mammary gland epithelial cell proliferation

MST1 MST1L

8.86e-0491042GO:0033601
GeneOntologyBiologicalProcessmammary duct terminal end bud growth

MST1 MST1L

8.86e-0491042GO:0060763
GeneOntologyCellularComponentextracellular matrix

VWC2 RELN DGCR6 COMP HAPLN2 COL6A5 MDK F12 MST1 EYS PLAT SERAC1 MUC5AC

2.51e-0565610513GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

VWC2 RELN DGCR6 COMP HAPLN2 COL6A5 MDK F12 MST1 EYS PLAT SERAC1 MUC5AC

2.59e-0565810513GO:0030312
GeneOntologyCellularComponentglycerol-3-phosphate dehydrogenase (FAD) complex

GPD1 GPD1L

7.47e-0531052GO:0009331
GeneOntologyCellularComponentextrinsic component of postsynaptic membrane

VWC2 DGKB DGKI

1.77e-04221053GO:0098890
GeneOntologyCellularComponentcollagen-containing extracellular matrix

VWC2 RELN COMP HAPLN2 COL6A5 MDK F12 MST1 EYS PLAT

3.37e-0453010510GO:0062023
GeneOntologyCellularComponentserine protease inhibitor complex

KLK8 PLAT

3.70e-0461052GO:0097180
GeneOntologyCellularComponentprotease inhibitor complex

KLK8 PLAT

6.86e-0481052GO:0097179
GeneOntologyCellularComponentextrinsic component of synaptic membrane

VWC2 DGKB DGKI

7.17e-04351053GO:0099243
GeneOntologyCellularComponentextrinsic component of postsynaptic density membrane

DGKB DGKI

1.10e-03101052GO:0099147
GeneOntologyCellularComponentSchaffer collateral - CA1 synapse

DGKB DGKZ P2RX3 DGKI PLAT

1.12e-031551055GO:0098685
GeneOntologyCellularComponentpeptidase inhibitor complex

KLK8 PLAT

1.33e-03111052GO:1904090
GeneOntologyCellularComponentextrinsic component of postsynaptic specialization membrane

DGKB DGKI

1.60e-03121052GO:0098892
DomainDAGK_acc

DGKB DGKG DGKZ DGKE DGKH DGKI

3.93e-1210996PF00609
DomainDiacylglycerol_kin_accessory

DGKB DGKG DGKZ DGKE DGKH DGKI

3.93e-1210996IPR000756
DomainDAGKa

DGKB DGKG DGKZ DGKE DGKH DGKI

3.93e-1210996SM00045
DomainDAGKc

DGKB DGKG DGKZ DGKE DGKH DGKI

5.52e-1114996SM00046
DomainDiacylglycerol_kinase_cat_dom

DGKB DGKG DGKZ DGKE DGKH DGKI

9.16e-1115996IPR001206
DomainDAGK_cat

DGKB DGKG DGKZ DGKE DGKH DGKI

9.16e-1115996PF00781
DomainDAGK

DGKB DGKG DGKZ DGKE DGKH DGKI

9.16e-1115996PS50146
DomainNAD/diacylglycerol_kinase

DGKB DGKG DGKZ DGKE DGKH DGKI

2.25e-1017996IPR016064
DomainC1_1

DGKB DGKG DGKZ DGKE DGKH PRKD3 DGKI

2.02e-0857997PF00130
DomainZF_DAG_PE_1

DGKB DGKG DGKZ DGKE DGKH PRKD3 DGKI

4.60e-0864997PS00479
DomainZF_DAG_PE_2

DGKB DGKG DGKZ DGKE DGKH PRKD3 DGKI

4.60e-0864997PS50081
DomainC1

DGKB DGKG DGKZ DGKE DGKH PRKD3 DGKI

5.13e-0865997SM00109
DomainPE/DAG-bd

DGKB DGKG DGKZ DGKE DGKH PRKD3 DGKI

5.72e-0866997IPR002219
DomainPeptidase_S1A

KLK12 OVCH1 F12 TMPRSS11B MST1 KLK8 PLAT MST1L

1.51e-07113998IPR001314
DomainTRYPSIN_DOM

KLK12 OVCH1 F12 TMPRSS11B MST1 KLK8 PLAT MST1L

1.74e-07115998PS50240
DomainTryp_SPc

KLK12 OVCH1 F12 TMPRSS11B MST1 KLK8 PLAT MST1L

1.98e-07117998SM00020
DomainTrypsin

KLK12 OVCH1 F12 TMPRSS11B MST1 KLK8 PLAT MST1L

2.57e-07121998PF00089
DomainTrypsin_dom

KLK12 OVCH1 F12 TMPRSS11B MST1 KLK8 PLAT MST1L

2.57e-07121998IPR001254
DomainPeptidase_S1_PA

KLK12 OVCH1 F12 TMPRSS11B MST1 KLK8 PLAT MST1L

2.92e-07123998IPR009003
DomainKringle

F12 MST1 PLAT MST1L

1.68e-0617994IPR000001
DomainKringle_CS

F12 MST1 PLAT MST1L

1.68e-0617994IPR018056
DomainKRINGLE_2

F12 MST1 PLAT MST1L

1.68e-0617994PS50070
DomainKringle

F12 MST1 PLAT MST1L

1.68e-0617994PF00051
DomainKRINGLE_1

F12 MST1 PLAT MST1L

1.68e-0617994PS00021
DomainKR

F12 MST1 PLAT MST1L

1.68e-0617994SM00130
DomainTRYPSIN_HIS

KLK12 OVCH1 F12 TMPRSS11B KLK8 PLAT

1.80e-05103996IPR018114
DomainTRYPSIN_SER

KLK12 OVCH1 F12 TMPRSS11B KLK8 PLAT

2.12e-05106996PS00135
DomainTRYPSIN_HIS

KLK12 OVCH1 F12 TMPRSS11B KLK8 PLAT

2.23e-05107996PS00134
DomainKringle-like

F12 MST1 PLAT MST1L

2.38e-0532994IPR013806
DomainPrenylcys_lyase

PCYOX1L PCYOX1

2.78e-052992PF07156
DomainDNA_topoisoIV

TOP2A TOP2B

2.78e-052992PF00521
DomainAPS_kinase

PAPSS2 PAPSS1

2.78e-052992IPR002891
DomainSulphate_adenylyltransferase

PAPSS2 PAPSS1

2.78e-052992IPR002650
DomainG3P_DH_NAD-dep_N

GPD1 GPD1L

2.78e-052992IPR011128
DomainATP-Sase_PUA-like_dom

PAPSS2 PAPSS1

2.78e-052992IPR025980
DomainTopo_IIA_A/C_ab

TOP2A TOP2B

2.78e-052992IPR013758
DomainTopo_IIA_A_a

TOP2A TOP2B

2.78e-052992IPR013757
DomainTopo_IIA_cen_dom

TOP2A TOP2B

2.78e-052992IPR013759
Domain-

TOP2A TOP2B

2.78e-0529923.40.50.670
DomainDTHCT

TOP2A TOP2B

2.78e-052992IPR012542
DomainTOP4c

TOP2A TOP2B

2.78e-052992SM00434
DomainTOP2c

TOP2A TOP2B

2.78e-052992SM00433
DomainTopo_IIA-like_dom

TOP2A TOP2B

2.78e-052992IPR013760
DomainNAD_Gly3P_dh_C

GPD1 GPD1L

2.78e-052992PF07479
DomainTopo_IIA_bsu_dom2

TOP2A TOP2B

2.78e-052992IPR013506
DomainDTHCT

TOP2A TOP2B

2.78e-052992PF08070
DomainNAD_Gly3P_dh_N

GPD1 GPD1L

2.78e-052992PF01210
DomainNAD_G3PDH

GPD1 GPD1L

2.78e-052992PS00957
DomainSulfurylase_cat_dom

PAPSS2 PAPSS1

2.78e-052992IPR024951
DomainG3P_DH_NAD-dep

GPD1 GPD1L

2.78e-052992IPR006168
DomainDNA_gyraseB

TOP2A TOP2B

2.78e-052992PF00204
DomainPrenylcys_lyase

PCYOX1L PCYOX1

2.78e-052992IPR010795
Domain-

TOP2A TOP2B

2.78e-0529921.10.268.10
DomainPrenylcysteine_Oxase

PCYOX1L PCYOX1

2.78e-052992IPR017046
DomainATP-sulfurylase

PAPSS2 PAPSS1

2.78e-052992PF01747
DomainG3P_DH_NAD-dep_C

GPD1 GPD1L

2.78e-052992IPR006109
DomainTOPRIM_C

TOP2A TOP2B

2.78e-052992IPR031660
DomainTOPRIM_C

TOP2A TOP2B

2.78e-052992PF16898
Domain-

TOP2A TOP2B

2.78e-0529923.90.199.10
DomainPUA_2

PAPSS2 PAPSS1

2.78e-052992PF14306
DomainTopoIIA_CS

TOP2A TOP2B

2.78e-052992IPR018522
DomainG3P_DH_NAD-dep_euk

GPD1 GPD1L

2.78e-052992IPR017751
DomainTopo_IIA_A/C

TOP2A TOP2B

2.78e-052992IPR002205
DomainTopo_IIA

TOP2A TOP2B

2.78e-052992IPR001241
DomainTOPOISOMERASE_II

TOP2A TOP2B

2.78e-052992PS00177
Domain-

TOP2A TOP2B

8.32e-0539923.30.1360.40
DomainDAG_kinase_N

DGKB DGKG

8.32e-053992PF14513
DomainArg_repress_C-like

TOP2A TOP2B

8.32e-053992IPR024946
DomainDAG_kinase_typeI_N

DGKB DGKG

8.32e-053992IPR029477
Domain-

DGKB DGKG

8.32e-0539921.10.238.110
DomainTRYPSIN_SER

KLK12 OVCH1 F12 KLK8 PLAT

1.16e-0490995IPR033116
DomainFN1_2

F12 PLAT

1.66e-044992PS51091
DomainToprim_domain

TOP2A TOP2B

1.66e-044992IPR006171
DomainToprim

TOP2A TOP2B

1.66e-044992PF01751
Domainfn1

F12 PLAT

1.66e-044992PF00039
DomainFibronectin_type1

F12 PLAT

1.66e-044992IPR000083
DomainTOPRIM

TOP2A TOP2B

1.66e-044992PS50880
DomainFN1

F12 PLAT

1.66e-044992SM00058
DomainFN1_1

F12 PLAT

1.66e-044992PS01253
DomainEGF_3

RELN COMP F12 NELL2 EYS PLAT C7

2.55e-04235997PS50026
DomainPAN_AP

MST1 MST1L

2.75e-045992SM00473
DomainEGF-like_dom

RELN COMP F12 NELL2 EYS PLAT C7

3.61e-04249997IPR000742
DomainSec23/24_helical_dom

SEC23B SEC23A

4.11e-046992IPR006900
DomainSec23_24_beta_S

SEC23B SEC23A

4.11e-046992IPR012990
Domainzf-Sec23_Sec24

SEC23B SEC23A

4.11e-046992PF04810
DomainSec23_trunk

SEC23B SEC23A

4.11e-046992PF04811
DomainSec23_helical

SEC23B SEC23A

4.11e-046992PF04815
DomainSec23_BS

SEC23B SEC23A

4.11e-046992PF08033
DomainSec23/24_trunk_dom

SEC23B SEC23A

4.11e-046992IPR006896
DomainZnf_Sec23_Sec24

SEC23B SEC23A

4.11e-046992IPR006895
DomainEGF_1

RELN COMP F12 NELL2 EYS PLAT C7

4.17e-04255997PS00022
DomainVWC

VWC2 NELL2 MUC5AC

4.30e-0428993PF00093
DomainEGF-like_CS

RELN COMP F12 NELL2 EYS PLAT C7

4.79e-04261997IPR013032
DomainEGF_2

RELN COMP F12 NELL2 EYS PLAT C7

5.24e-04265997PS01186
DomainPAN

MST1 MST1L

5.74e-047992PS50948
DomainPan_app

MST1 MST1L

5.74e-047992IPR003609
DomainPAN_1

MST1 MST1L

5.74e-047992PF00024
DomainVWFC_1

VWC2 NELL2 MUC5AC

9.08e-0436993PS01208
DomainVWC

VWC2 NELL2 MUC5AC

1.07e-0338993SM00214
DomainVWFC_2

VWC2 NELL2 MUC5AC

1.07e-0338993PS50184
PathwayREACTOME_EFFECTS_OF_PIP2_HYDROLYSIS

DGKB DGKG DGKZ DGKE DGKH DGKI

3.55e-0925776MM14511
PathwayREACTOME_EFFECTS_OF_PIP2_HYDROLYSIS

DGKB DGKG DGKZ DGKE DGKH DGKI

5.89e-0927776M12123
PathwayKEGG_GLYCEROPHOSPHOLIPID_METABOLISM

GPD1 DGKB DGKG DGKZ DGKE DGKH GPD1L DGKI

8.49e-0977778M9131
PathwayKEGG_GLYCEROLIPID_METABOLISM

DGKB DGKG DGKZ DGKE DGKH DGKI

2.53e-0749776M15902
PathwayKEGG_PHOSPHATIDYLINOSITOL_SIGNALING_SYSTEM

DGKB DGKG DGKZ DGKE DGKH DGKI

3.52e-0676776M9052
PathwayREACTOME_PLATELET_ACTIVATION_SIGNALING_AND_AGGREGATION

DGKB DGKG DGKZ DGKE DGKH PCYOX1L DGKI FAM3C

7.77e-05257778MM15454
PathwayREACTOME_PLATELET_ACTIVATION_SIGNALING_AND_AGGREGATION

DGKB DGKG DGKZ DGKE DGKH PCYOX1L DGKI FAM3C

8.66e-05261778M1077
PathwayREACTOME_HEMOSTASIS

DGKB DGKG DGKZ DGKE DGKH F12 PCYOX1L P2RX3 DGKI PLAT FAM3C

2.58e-045717711MM14472
PathwayREACTOME_HEMOSTASIS

DGKB DGKG DGKZ DGKE DGKH F12 PCYOX1L P2RX3 DGKI PLAT FAM3C TUBB8B

2.92e-046797712M8395
PathwayKEGG_SELENOAMINO_ACID_METABOLISM

PAPSS2 PAPSS1 LCMT2

3.72e-0426773M7151
PathwayREACTOME_SIGNALING_BY_MST1

MST1 MST1L

4.36e-046772MM15492
PathwayREACTOME_TRANSPORT_AND_SYNTHESIS_OF_PAPS

PAPSS2 PAPSS1

4.36e-046772M27027
PathwayREACTOME_TRANSPORT_AND_SYNTHESIS_OF_PAPS

PAPSS2 PAPSS1

4.36e-046772MM14679
PathwayBIOCARTA_MSP_PATHWAY

MST1 MST1L

6.08e-047772MM1580
PathwayWP_MIR302367_PROMOTING_CARDIOMYOCYTE_PROLIFERATION

MST1 MST1L

8.07e-048772MM15986
PathwayREACTOME_G_ALPHA_Q_SIGNALLING_EVENTS

DGKB DGKG DGKZ DGKE DGKH DGKI

1.00e-03210776MM15043
Pubmed

Diacylglycerol kinase delta regulates protein kinase C and epidermal growth factor receptor signaling.

DGKB DGKG DGKZ DGKE DGKH DGKI

3.17e-1311106617021016
Pubmed

Biosynthesis of alkyl lysophosphatidic acid by diacylglycerol kinases.

DGKB DGKG DGKZ

2.74e-075106322627129
Pubmed

Nell1-deficient mice have reduced expression of extracellular matrix proteins causing cranial and vertebral defects.

RELN COMP HAPLN2 DGKG DGKE MDK PACSIN2

3.89e-06210106716537572
Pubmed

DNA topoisomerase II is dispensable for oocyte meiotic resumption but is essential for meiotic chromosome condensation and separation in mice.

TOP2A TOP2B

9.20e-062106224048577
Pubmed

A member of a family of sulfate-activating enzymes causes murine brachymorphism.

PAPSS2 PAPSS1

9.20e-06210629671738
Pubmed

Topoisomerase II alpha and topoisomerase II beta genes: characterization and mapping to human chromosomes 17 and 3, respectively.

TOP2A TOP2B

9.20e-06210621309226
Pubmed

Use of divalent metal ions in the dna cleavage reaction of human type II topoisomerases.

TOP2A TOP2B

9.20e-062106219222228
Pubmed

Evidence for a mutant allele of the gene for DNA topoisomerase II in adriamycin-resistant P388 murine leukemia cells.

TOP2A TOP2B

9.20e-06210622555055
Pubmed

Characterization of cDNA encoding the mouse DNA topoisomerase II that can complement the budding yeast top2 mutation.

TOP2A TOP2B

9.20e-06210621331984
Pubmed

Mst1 regulates post-infarction cardiac injury through the JNK-Drp1-mitochondrial fission pathway.

MST1 MST1L

9.20e-062106229760744
Pubmed

Doxorubicin-induced cardiotoxicity is maturation dependent due to the shift from topoisomerase IIα to IIβ in human stem cell derived cardiomyocytes.

TOP2A TOP2B

9.20e-062106231106979
Pubmed

A biochemical analysis of topoisomerase II alpha and beta kinase activity found in HIV-1 infected cells and virus.

TOP2A TOP2B

9.20e-062106216091284
Pubmed

Specific interaction of topoisomerase II beta and the CD3 epsilon chain of the T cell receptor complex.

CD3E TOP2B

9.20e-06210628626450
Pubmed

Kinetic analysis of human topoisomerase IIalpha and beta DNA binding by surface plasmon resonance.

TOP2A TOP2B

9.20e-062106214596941
Pubmed

Enhanced expression of DNA topoisomerase II genes in human medulloblastoma and its possible association with etoposide sensitivity.

TOP2A TOP2B

9.20e-062106217361331
Pubmed

Cloning, sequencing, and expression of human macrophage stimulating protein (MSP, MST1) confirms MSP as a member of the family of kringle proteins and locates the MSP gene on chromosome 3.

MST1 MST1L

9.20e-06210628393443
Pubmed

Mania- and anxiety-like behavior and impaired maternal care in female diacylglycerol kinase eta and iota double knockout mice.

DGKH DGKI

9.20e-062106230985063
Pubmed

Molecular cloning and characterization of the human topoisomerase IIalpha and IIbeta genes: evidence for isoform evolution through gene duplication.

TOP2A TOP2B

9.20e-062106210095062
Pubmed

MSP is a negative regulator of inflammation and lipogenesis in ex vivo models of non-alcoholic steatohepatitis.

MST1 MST1L

9.20e-062106227609031
Pubmed

Endocannabinoids and diacylglycerol kinase activity.

DGKZ DGKE

9.20e-062106221194521
Pubmed

Cloning and functional characterization of mammalian homologues of the COPII component Sec23.

SEC23B SEC23A

9.20e-06210628898360
Pubmed

Functional compatibility between isoform alpha and beta of type II DNA topoisomerase.

TOP2A TOP2B

9.20e-062106214996935
Pubmed

Hepatocyte growth factor-like protein is required for prostate tumor growth in the TRAMP mouse model.

MST1 MST1L

9.20e-062106224980820
Pubmed

Structural organization of the human TOP2A and TOP2B genes.

TOP2A TOP2B

9.20e-06210629795238
Pubmed

The distribution of DNA topoisomerase II isoforms in differentiated adult mouse tissues.

TOP2A TOP2B

9.20e-06210628241259
Pubmed

Mining topoisomerase isoforms in gastric cancer.

TOP2A TOP2B

9.20e-062106232535049
Pubmed

Different patterns of gene expression of topoisomerase II isoforms in differentiated tissues during murine development.

TOP2A TOP2B

9.20e-06210621380833
Pubmed

Dynamics of human DNA topoisomerases IIalpha and IIbeta in living cells.

TOP2A TOP2B

9.20e-062106211927602
Pubmed

Topoisomerase II binds importin alpha isoforms and exportin/CRM1 but does not shuttle between the nucleus and cytoplasm in proliferating cells.

TOP2A TOP2B

9.20e-062106217182034
Pubmed

Mst1 deletion reduces hyperglycemia-mediated vascular dysfunction via attenuating mitochondrial fission and modulating the JNK signaling pathway.

MST1 MST1L

9.20e-062106231206688
Pubmed

Natural variation in a single amino acid substitution underlies physiological responses to topoisomerase II poisons.

TOP2A TOP2B

9.20e-062106228700616
Pubmed

Nuclear localization of PAPS synthetase 1: a sulfate activation pathway in the nucleus of eukaryotic cells.

PAPSS2 PAPSS1

9.20e-062106210657990
Pubmed

Predictors and mechanisms of epilepsy occurrence in cerebral gliomas: What to look for in clinicopathology.

TOP2A TOP2B

9.20e-062106228087392
Pubmed

Roles of the C-terminal domains of topoisomerase IIα and topoisomerase IIβ in regulation of the decatenation checkpoint.

TOP2A TOP2B

9.20e-062106228472494
Pubmed

Human 3'-phosphoadenosine 5'-phosphosulfate synthetase 1 (PAPSS1) and PAPSS2: gene cloning, characterization and chromosomal localization.

PAPSS2 PAPSS1

9.20e-062106210679223
Pubmed

Association of immunophenotype with expression of topoisomerase II α and β in adult acute myeloid leukemia.

TOP2A TOP2B

9.20e-062106232218491
Pubmed

Structure of the human D1F15S1A locus: a chromosome 1 locus with 97% identity to the chromosome 3 gene coding for hepatocyte growth factor-like protein.

MST1 MST1L

9.20e-062106210728827
Pubmed

Genetically selected Marchigian Sardinian alcohol-preferring (msP) rats: an animal model to study the neurobiology of alcoholism.

MST1 MST1L

9.20e-062106216961763
Pubmed

Mutations in orthologous genes in human spondyloepimetaphyseal dysplasia and the brachymorphic mouse.

PAPSS2 PAPSS1

9.20e-06210629771708
Pubmed

Inhibiting endothelial cell Mst1 attenuates acute lung injury in mice.

MST1 MST1L

9.20e-062106239253972
Pubmed

Characterization and expression of human bifunctional 3'-phosphoadenosine 5'-phosphosulphate synthase isoforms.

PAPSS2 PAPSS1

9.20e-062106211931637
Pubmed

Involvement of human topoisomerase II isoforms in HIV-1 reverse transcription.

TOP2A TOP2B

9.20e-062106223399433
Pubmed

Ciprofloxacin impairs mitochondrial DNA replication initiation through inhibition of Topoisomerase 2.

TOP2A TOP2B

9.20e-062106230169847
Pubmed

Enhanced processing of UVA-irradiated DNA by human topoisomerase II in living cells.

TOP2A TOP2B

9.20e-062106215044480
Pubmed

C-terminal regions of topoisomerase IIalpha and IIbeta determine isoform-specific functioning of the enzymes in vivo.

TOP2A TOP2B

9.20e-062106217526531
Pubmed

Cerebral ischemia-reperfusion is modulated by macrophage-stimulating 1 through the MAPK-ERK signaling pathway.

MST1 MST1L

9.20e-062106232017081
Pubmed

Functions of the COPII gene paralogs SEC23A and SEC23B are interchangeable in vivo.

SEC23B SEC23A

9.20e-062106230065114
Pubmed

Mst1 inhibition attenuates non-alcoholic fatty liver disease via reversing Parkin-related mitophagy.

MST1 MST1L

9.20e-062106230708325
Pubmed

Functional consequences of the macrophage stimulating protein 689C inflammatory bowel disease risk allele.

MST1 MST1L

9.20e-062106224409221
Pubmed

The distribution and expression of the two isoforms of DNA topoisomerase II in normal and neoplastic human tissues.

TOP2A TOP2B

9.20e-06210629155056
Pubmed

Deficiency of diacylglycerol kinase η induces lithium-sensitive mania-like behavior.

DGKG DGKH

9.20e-062106227167678
Pubmed

Melatonin alleviates postinfarction cardiac remodeling and dysfunction by inhibiting Mst1.

MST1 MST1L

9.20e-062106227696525
Pubmed

DNA topoisomerase II distribution in mouse preimplantation embryos.

TOP2A TOP2B

9.20e-062106211835579
Pubmed

Hepatocyte-specific expression of the mouse hepatocyte growth factor-like protein.

MST1 MST1L

9.20e-06210628340069
Pubmed

Biological effects of targeted inactivation of hepatocyte growth factor-like protein in mice.

MST1 MST1L

9.20e-06210629486989
Pubmed

Characterization and immunological identification of cDNA clones encoding two human DNA topoisomerase II isozymes.

TOP2A TOP2B

9.20e-06210622556712
Pubmed

A study of the topoisomerase II activity in HIV-1 replication using the ferrocene derivatives as probes.

TOP2A TOP2B

9.20e-062106216712776
Pubmed

Active heterodimers are formed from human DNA topoisomerase II alpha and II beta isoforms.

TOP2A TOP2B

9.20e-06210628710863
Pubmed

Distinct expression patterns for type II topoisomerases IIA and IIB in the early foetal human telencephalon.

TOP2A TOP2B

9.20e-062106226612825
Pubmed

Using a biochemical approach to identify the primary dimerization regions in human DNA topoisomerase IIalpha.

TOP2A TOP2B

9.20e-062106210473615
Pubmed

Treatment with XMU-MP-1 erases hyperglycaemic memory in hearts of diabetic mice.

MST1 MST1L

9.20e-062106233887258
Pubmed

Cellular distribution of mammalian DNA topoisomerase II is determined by its catalytically dispensable C-terminal domain.

TOP2A TOP2B

9.20e-06210629224616
Pubmed

DNA damage response during chromatin remodeling in elongating spermatids of mice.

TOP2A TOP2B

9.20e-062106218032420
Pubmed

Discrete localization of different DNA topoisomerases in HeLa and K562 cell nuclei and subnuclear fractions.

TOP2A TOP2B

9.20e-06210628299728
Pubmed

Maternal topoisomerase II alpha, not topoisomerase II beta, enables embryonic development of zebrafish top2a-/- mutants.

TOP2A TOP2B

9.20e-062106222111588
Pubmed

HGFL supports mammary tumorigenesis by enhancing tumor cell intrinsic survival and influencing macrophage and T-cell responses.

MST1 MST1L

9.20e-062106225938541
Pubmed

Roles of DNA topoisomerase II isozymes in chemotherapy and secondary malignancies.

TOP2A TOP2B

9.20e-062106217578914
Pubmed

Diacylglycerol kinase epsilon is selective for both acyl chains of phosphatidic acid or diacylglycerol.

DGKZ DGKE

9.20e-062106219744926
Pubmed

Human PAPS synthase isoforms are dynamically regulated enzymes with access to nucleus and cytoplasm.

PAPSS2 PAPSS1

9.20e-062106222242175
Pubmed

Extracellular proteolysis of reelin by tissue plasminogen activator following synaptic potentiation.

RELN PLAT

9.20e-062106224892761
Pubmed

Nuclear interactions of topoisomerase II alpha and beta with phospholipid scramblase 1.

TOP2A TOP2B

2.76e-053106217567603
Pubmed

Deacetylase activity associates with topoisomerase II and is necessary for etoposide-induced apoptosis.

TOP2A TOP2B

2.76e-053106211136718
Pubmed

The Ron/STK receptor tyrosine kinase is essential for peri-implantation development in the mouse.

MST1 MST1L

2.76e-053106210225971
Pubmed

Inhibition of MST1 ameliorates neuronal apoptosis via GSK3β/β-TrCP/NRF2 pathway in spinal cord injury accompanied by diabetes.

MST1 MST1L

2.76e-053106238430683
Pubmed

Macrophage stimulating protein is a target-derived neurotrophic factor for developing sensory and sympathetic neurons.

MST1 MST1L

2.76e-053106212538524
Pubmed

Mst1 controls lymphocyte trafficking and interstitial motility within lymph nodes.

MST1 MST1L

2.76e-053106219339990
Pubmed

TRAF2 functions as an activator switch in the reactive oxygen species-induced stimulation of MST1.

MST1 MST1L

2.76e-053106226698664
Pubmed

Proteolytic degradation of topoisomerase II (Top2) enables the processing of Top2·DNA and Top2·RNA covalent complexes by tyrosyl-DNA-phosphodiesterase 2 (TDP2).

TOP2A TOP2B

2.76e-053106224808172
Pubmed

Melatonin activates Parkin translocation and rescues the impaired mitophagy activity of diabetic cardiomyopathy through Mst1 inhibition.

MST1 MST1L

2.76e-053106230063115
Pubmed

Identification of functional nuclear export sequences in human topoisomerase IIalpha and beta.

TOP2A TOP2B

2.76e-053106212821127
Pubmed

Mst1-mediated phosphorylation of Bcl-xL is required for myocardial reperfusion injury.

MST1 MST1L

2.76e-053106227218122
Pubmed

Inhibition of endogenous Mst1 prevents apoptosis and cardiac dysfunction without affecting cardiac hypertrophy after myocardial infarction.

MST1 MST1L

2.76e-053106217395874
Pubmed

Genetic deletion of Mst1 alters T cell function and protects against autoimmunity.

MST1 MST1L

2.76e-053106224852423
Pubmed

CD40L+ CD4+ memory T cells migrate in a CD62P-dependent fashion into reactive lymph nodes and license dendritic cells for T cell priming.

CXCR3 CD3E

2.76e-053106218838544
Pubmed

Mst1 participates in the atherosclerosis progression through macrophage autophagy inhibition and macrophage apoptosis enhancement.

MST1 MST1L

2.76e-053106227496379
Pubmed

Macrophage-stimulating protein cooperates with erythropoietin to induce colony formation and MAP kinase activation in primary erythroid progenitor cells.

MST1 MST1L

2.76e-053106212804176
Pubmed

Receptor tyrosine kinase Ron is expressed in mouse reproductive tissues during embryo implantation and is important in trophoblast cell function.

MST1 MST1L

2.76e-053106212606483
Pubmed

DNA topoisomerase II inhibitors induce macrophage ABCA1 expression and cholesterol efflux-an LXR-dependent mechanism.

TOP2A TOP2B

2.76e-053106223466610
Pubmed

Mst1-mediated phosphorylation of Nur77 improves the endometrial receptivity in human and mice.

MST1 MST1L

2.76e-053106236623453
Pubmed

Hippo Kinase MST1-Mediated Cell Metabolism Reprograms the Homeostasis and Differentiation of Granulocyte Progenitor Cells.

MST1 MST1L

2.76e-053106237184367
Pubmed

Human topoisomerase IIalpha and IIbeta interact with the C-terminal region of p53.

TOP2A TOP2B

2.76e-053106210666337
Pubmed

CircRbms1 fosters MST1 mRNA and protein levels to motivate myocardial ischaemia-reperfusion injury via autophagic status.

MST1 MST1L

2.76e-053106238288506
Pubmed

The proto-oncogene RON is involved in development of epithelial, bone and neuro-endocrine tissues.

MST1 MST1L

2.76e-05310628545120
Pubmed

Hepatocyte growth factor-like protein is a positive regulator of early mammary gland ductal morphogenesis.

MST1 MST1L

2.76e-053106225049204
Pubmed

Characterization of the mouse cDNA and gene coding for a hepatocyte growth factor-like protein: expression during development.

MST1 MST1L

2.76e-05310621832957
Pubmed

Nucleophagy contributes to genome stability through degradation of type II topoisomerases A and B and nucleolar components.

TOP2A TOP2B

2.76e-053106236633090
Pubmed

Activation of pro-survival CaMK4β/CREB and pro-death MST1 signaling at early and late times during a mouse model of prion disease.

MST1 MST1L

2.76e-053106225183307
Pubmed

Protein kinase C delta activates topoisomerase IIalpha to induce apoptotic cell death in response to DNA damage.

TOP2A TOP2B

2.76e-053106216611985
Pubmed

MST1 mediates neuronal loss and cognitive deficits: A novel therapeutic target for Alzheimer's disease.

MST1 MST1L

2.76e-053106235525373
Pubmed

MST1 coordinately regulates autophagy and apoptosis in diabetic cardiomyopathy in mice.

MST1 MST1L

2.76e-053106227510910
Cytoband1q23.1

TTC24 HAPLN2 OR6N1

1.69e-044610631q23.1
GeneFamilyEF-hand domain containing|Diacylglycerol kinases

DGKB DGKG DGKZ DGKE DGKH DGKI

1.56e-13105761178
GeneFamilyTopoisomerases

TOP2A TOP2B

1.45e-0465721050
GeneFamilyKallikreins

KLK12 KLK8

1.14e-0316572616
ToppCelldroplet-Kidney-nan-21m-Epithelial-Epcam____kidney_proximal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CMBL GPD1 SLC22A23 ALDH8A1 PIPOX SLC13A3 MDK PAPSS2

1.44e-0818410683d7dd193a0826cc7a4e454a29236a16c315e5965
ToppCelldroplet-Kidney-nan-21m-Epithelial-kidney_proximal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CMBL GPD1 SLC22A23 ALDH8A1 PIPOX SLC13A3 MDK PAPSS2

1.44e-08184106845577ff91c3b2b303acd97239dde2463ea7a429c
ToppCelldroplet-Kidney-nan-18m-Epithelial-Epcam____kidney_proximal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CMBL GPD1 SLC22A23 ALDH8A1 PIPOX MDK PAPSS2

2.96e-071841067c86ed59fed687cdaaf7e9c4418d2e3e2c4111cca
ToppCelldroplet-Kidney-nan-18m-Epithelial-kidney_proximal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CMBL GPD1 SLC22A23 ALDH8A1 PIPOX MDK PAPSS2

2.96e-0718410677c256bcfa07c5ff55aad0833e8712b0456b5832b
ToppCelldroplet-Kidney-nan-3m-Epithelial-Epcam____kidney_proximal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CMBL GPD1 SLC22A23 ALDH8A1 PIPOX SLC13A3 PAPSS2

3.07e-0718510673e3217c99719fd1d2fa94e16be7712a7e5077152
ToppCelldroplet-Kidney-nan-3m-Epithelial-kidney_proximal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CMBL GPD1 SLC22A23 ALDH8A1 PIPOX SLC13A3 PAPSS2

3.07e-0718510670ff4148b4701003d9d594e0da8261176fb13aa59
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Degenerative_Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

EFS PIPOX TKTL1 FAM3C C7 PLIN1

1.32e-06145106607acbf086cffce0628accf078d31bf190f803988
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c11-GNLY|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CXCR3 OVCH1 PCYOX1L CD3E GALNT17 TOP2A

1.55e-0614910661328ce0104d40215ee68abfdbf74eb47b87a7b5b
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m-Lymphocytic-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CXCR3 ARHGAP30 MST1 CD3E CD19 KLK8

2.90e-061661066b7027802cac6ebf3c4a19ef11c9164d92694a4eb
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m-Lymphocytic|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CXCR3 ARHGAP30 MST1 CD3E CD19 KLK8

2.90e-061661066dbb73742db00982539b1800aef8af2801b3a0598
ToppCelldroplet-Lung-3m-Hematologic-lymphocytic-CD4-positive,_alpha-beta_T_cell-CD4-positive,_alpha-beta_T_cell_l9|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CXCR3 HAPLN2 ARHGAP30 TKTL1 CD3E KLK8

3.68e-061731066da0f1461643294f92e20b5e456a50211a2780a91
ToppCell3'-Child09-12-SmallIntestine-Hematopoietic-T_cells-CD8_Tmem|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CXCR3 ARHGAP30 LIM2 NELL2 CD3E DTHD1

5.24e-06184106661e2a8b9a42e5788fb4e47c77cc5de65420acbfa
ToppCell(210)_NKT_cell|World / immune cells in Peripheral Blood (logTPM normalization)

TKTL1 LIM2 EYS CD3E DTHD1 TTC38

6.69e-06192106608dc0c019c594da7b9944db8fd706aa7780e6ae9
ToppCell(21)_NKT_cell|World / immune cells in Peripheral Blood (logTPM normalization)

TKTL1 LIM2 EYS CD3E DTHD1 TTC38

6.69e-061921066b0a573ddde2978485a857b8261ee1ee5ef68ecef
ToppCell10x5'v1-week_14-16-Lymphocytic_NK|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

CXCR3 TKTL1 LIM2 CD3E DTHD1 TTC38

7.09e-0619410665a859885c0f9b8554b0d203e371c70928ad4418f
ToppCell10x5'v1-week_14-16-Lymphocytic_NK-T_NK|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

CXCR3 TKTL1 LIM2 CD3E DTHD1 TTC38

7.09e-0619410667d35ac70ba966eb1fee4197f7de6d6116326a442
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CMBL GPD1 ALDH8A1 PIPOX SLC13A3 TTC38

7.74e-0619710669b038dac4d4d306aa40ec07d79374c4fe9c604a6
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CMBL GPD1 ALDH8A1 PIPOX SLC13A3 TTC38

7.97e-06198106672733b6149b797ac11cc108bc80428b77fbbba78
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CMBL GPD1 ALDH8A1 PIPOX SLC13A3 TTC38

7.97e-061981066f23559ce6072e3c323f6791ff95269271b0f7ff1
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CMBL GPD1 ALDH8A1 PIPOX SLC13A3 TTC38

8.20e-0619910664bde35e5df019189433d65d415e29a0c1145ac66
ToppCellE18.5-samps-Epithelial-Alveolar_epithelial-AT2_progenitor|E18.5-samps / Age Group, Lineage, Cell class and subclass

FMO6P CD3E SCAMP5 TARBP1 MFSD3

1.24e-051251065b5fed0e0295aa8ad323c318b59bf23cde3e758c8
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c13-HAVCR2|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CXCR3 COMP ALDH8A1 CPOX DTHD1

1.79e-051351065641d42a005ff61f21e6cda02bfbd0bd1d4ba2faa
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c02-AQP3|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

DGKB MDK PCYOX1L CD3E TOP2B

2.62e-051461065159dd157a74f3c27dc1a1dcbbf0ed8f9462cac9e
ToppCellSmart-seq2-blood_(Smart-seq2)-hematologic-hematopoietic_progenitor-hematopoietic_stem_cell|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

CMBL MDK MYCNOS SCAMP5 DHRS9

2.88e-051491065e99b7cd3728ce76b365526734c2e7f845b2e62c8
ToppCellSmart-seq2-blood_(Smart-seq2)-hematologic-hematopoietic_progenitor|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

CMBL MDK MYCNOS SCAMP5 DHRS9

2.88e-0514910656a28dd4530ed411747fdfe743db138a1b5547ed7
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

HAPLN2 DGKB DGKG F12 GALNT17

3.17e-051521065bd1f36b436d8ab7dd8420f595b97d851eab31a38
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

HAPLN2 DGKB DGKG F12 GALNT17

3.17e-051521065ee329249a034a969a16b26a224aa04249d67382d
ToppCellmild_COVID-19_(asymptomatic)-CD8+_T_naive|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)

CEP76 NELL2 EYS CD3E SCART1

3.48e-051551065e2c901d5c9e42d25d7702e5e8fc19b06f7c817be
ToppCelldroplet-Liver-LIVER_NPC-30m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CXCR3 ARHGEF18 CD3E CD19 KLK8

3.93e-051591065997963d879e5819683793cddf5e1acff1b81a1b8
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

CXCR3 DNAH10 CD3E GALNT17 TOP2A

3.93e-0515910652233fee5dcdb6c7dee5b1bd8efbc07d86b339927
ToppCelldroplet-Liver-LIVER_NPC|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CXCR3 ARHGEF18 CD3E CD19 KLK8

3.93e-051591065e4eaa88772835d6b78e1a18a0cec52de51e80339
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m-Lymphocytic-CD8-positive,_alpha-beta_T_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CXCR3 ARHGAP30 MST1 CD3E KLK8

4.17e-05161106554eda81a570e422b35fcea799e640c7654122969
ToppCellBrain_organoid-organoid_Velasco_nature-3_mon-Neuronal-Cajal-Retzius|3_mon / Sample Type, Dataset, Time_group, and Cell type.

GPD1 VWC2 RELN THSD7B C7

4.30e-0516210651f589a763f3fd4e1e612809ef3903879d47dc1d8
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PCYOX1L DGKI SERAC1 TOP2A ADGRA3

4.43e-0516310653efbbdc9cb2613bb76d8c2f07cd4ec1a2c51a622
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-Epcam____proximal_tube_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CMBL ALDH8A1 PIPOX SLC13A3 PANK1

4.69e-051651065082f62f759a0b16ab56fad6dd4c4dd70b4f18a5c
ToppCellfacs-Kidney-nan-24m-Epithelial-epithelial_cell_of_proximal_tubule|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CMBL ALDH8A1 PIPOX SLC13A3 PANK1

4.69e-051651065906321cb5f299d77436fb5540fd8c52d7532beca
ToppCellfacs-Kidney-nan-24m-Epithelial-epithelial_cell_of_proximal_tubule|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CMBL ALDH8A1 PIPOX SLC13A3 PANK1

4.69e-05165106502a09d0918b103aca21c36b42c5a8a8ebad8686c
ToppCellfacs-Marrow-B-cells-18m-Hematologic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN SLC25A21 TTC24 SLC22A23 FKBP2

4.69e-051651065361a605d8f833d9ec54b120480dce397da35f9c3
ToppCelldroplet-Kidney-nan-18m-Epithelial-Epcam____proximal_tube_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CMBL ALDH8A1 SLC13A3 PAPSS2 PANK1

4.83e-0516610658ab18c9d911eb3a9970bba7a769294b0927538f7
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_104|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

EFS PIPOX NIF3L1 MDK PLIN1

4.83e-051661065c11dcf9705b85ac3da6ae86358f5ffd64ae8327e
ToppCell3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_T/NK-CD8-positive,_alpha-beta_T_cell-CD8_T_cells-CD8_T_cells_L.1.1.0.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CXCR3 DGKB CEP76 CD3E RBM6

4.83e-05166106526f3d5e5e30b63b09b89cda23c423d12d887631f
ToppCelldroplet-Kidney-nan-18m-Epithelial-epithelial_cell_of_proximal_tubule|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CMBL ALDH8A1 SLC13A3 PAPSS2 PANK1

5.11e-051681065dd48da83c32d41a62f80cd7e5e5c64e42776fa27
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-Epcam____proximal_tube_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CMBL GPD1 ALDH8A1 PIPOX PANK1

5.11e-051681065624cf8f439c0a3c877927e085ec260ca79896b5a
ToppCelldroplet-Liver-LIVER_NPC-30m-Lymphocytic|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CXCR3 ARHGEF18 CD3E CD19 KLK8

5.41e-05170106526178277bf9c7f2f06b5c0b03d4b69d78e9580c4
ToppCelldroplet-Liver-Npc-18m-Lymphocytic-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CXCR3 ARHGEF18 CD3E KLK8 ADGRF3

5.56e-051711065872b3b33cd3893d63c45617db0269692430b0e8b
ToppCelldroplet-Kidney-nan-3m-Epithelial-Epcam____proximal_tube_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CMBL GPD1 PIPOX SLC13A3 PANK1

5.56e-05171106548fc4eca18b102b5ec5050f758281292ee8e10c6
ToppCellnormal_Pleural_Fluid-T/NK_cells-Cytotoxic_CD8+_T|normal_Pleural_Fluid / Location, Cell class and cell subclass

CXCR3 DGKZ CD3E DTHD1 TTC38

5.56e-0517110656be81c20f4e962b414afcedfe478dd59c510d1e1
ToppCelldroplet-Kidney-nan-3m-Epithelial-epithelial_cell_of_proximal_tubule|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CMBL GPD1 PIPOX SLC13A3 PANK1

5.56e-05171106505fcc72df50a380a913821b5781d9621df37d328
ToppCelldroplet-Fat-Mat-18m-Lymphocytic-lymphocyte|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ALDH8A1 ARHGEF18 CD3E CD19 KLK8

5.71e-051721065226de1a5d4a360d3ae01b0235fea19521ec623a0
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Immune-Lymphocytic_T/NK-T_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CXCR3 ARHGAP30 NELL2 CD3E DTHD1

6.04e-05174106547e308a777c927ae69ed344cb3dd8561bf2c48a5
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Immune-Lymphocytic_T/NK-T_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CXCR3 ARHGAP30 NELL2 CD3E DTHD1

6.04e-051741065a92c745d20633909db0f08effa13fc738fda79a6
ToppCell3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NDST2 KLK12 MDK TMPRSS11B MUC5AC

6.20e-0517510658252ddc2ca95071381f0354aefb70c4714828491
ToppCell3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NDST2 KLK12 MDK TMPRSS11B MUC5AC

6.20e-0517510658ccf60fc469059d7aaf4e6ce54159db2962e0060
ToppCellPND10-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_G2M|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HLCS DGKG ARHGAP30 WDR90 TOP2A

6.37e-05176106590f8bb11f339f67f08692a0c33dd420f5cda2861
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Immune-Lymphocytic_T/NK|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CXCR3 ARHGAP30 NELL2 CD3E DTHD1

6.90e-051791065874a9afa91774221c9c1775aa4968ba0aea7b554
ToppCellFrontal_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Col15a1_(Col15a1)-|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

COMP DNAH10 CD3E SH3RF2

6.93e-05921064d2c1d25e5bb6ba4f406e916e3c0a5ad05492e59d
ToppCellFrontal_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Col15a1_(Col15a1)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

COMP DNAH10 CD3E SH3RF2

6.93e-05921064926e02725a03d8473eda25d4aef63e34a6566224
ToppCelldroplet-Kidney-nan-3m-Epithelial-kidney_proximal_straight_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CMBL GPD1 ALDH8A1 SLC13A3 PAPSS2

7.09e-051801065b34d933cdabf692f02eaaf65c2aaca1fb9510627
ToppCelldroplet-Kidney|droplet / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPD1 ALDH8A1 PIPOX SLC13A3 PAPSS2

7.09e-0518010657e5f497699876ac8e1ce780626c6f5a1f6f5f079
ToppCellmoderate-Myeloid-pDC|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

CXCR3 TTC24 SCAMP5 RBM6 TARBP1

7.09e-0518010651d8df7df03a71f49d6683554d3c948ce90dda42e
ToppCellfacs-Kidney-nan-18m-Epithelial-kidney_collecting_duct_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CMBL GPD1 ALDH8A1 SLC13A3 PAPSS2

7.27e-051811065bec7076efe94898213a62db72d171d737949977e
ToppCellfacs-Kidney-nan-18m-Epithelial-kidney_collecting_duct_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CMBL GPD1 ALDH8A1 SLC13A3 PAPSS2

7.27e-051811065cf149b30b814cf87c9e923ef502cadf7fe4a3597
ToppCell356C-Lymphocytic-NK_cells-NK_cell_B2|356C / Donor, Lineage, Cell class and subclass (all cells)

ARHGAP30 TKTL1 LIM2 DTHD1 TTC38

7.47e-05182106552baef8173df0a55307c375674a37c2488066738
ToppCell3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)-Goblet_(subsegmental)_L.0.4.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KLK12 MDK DHRS9 MUC5AC FKBP2

7.47e-05182106594e70746e35a3062015d4b83ee545f4f84f47420
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c13-HAVCR2|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CXCR3 TTC24 CD3E DTHD1 TOP2A

7.47e-0518210656c9a48037fa002bc528875538bdaaf15696d68b6
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-kidney_proximal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CMBL GPD1 ALDH8A1 PIPOX MDK

7.66e-05183106592f54c267135cb5edbcacd26a0f29e62469bb7e5
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-Epcam____kidney_proximal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CMBL GPD1 ALDH8A1 PIPOX MDK

7.66e-0518310655c4f7d02ba3a3c4a22ac71302e7c9a47e205eef5
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Immune-Lymphocytic_T/NK|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CXCR3 ARHGAP30 NELL2 CD3E DTHD1

7.86e-0518410656119140287ab4b88e41194bf8d6f77ae264b3b98
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Immune-Lymphocytic_T/NK-T_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CXCR3 ARHGAP30 NELL2 CD3E DTHD1

7.86e-0518410656ce9aea2c1c9098f37bdf5135b5e2192ef03b50b
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Immune-Lymphocytic_T/NK-T_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CXCR3 ARHGAP30 NELL2 CD3E DTHD1

7.86e-051841065895f7492d47c4782809bbb125c258127de04f888
ToppCell10x5'v1-week_12-13-Lymphocytic_NK-T_NK-CD56_bright_NK|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

CXCR3 TKTL1 LIM2 CD3E DTHD1

8.06e-051851065593eceb3dfcc662c892a840ba29ab687c6886c01
ToppCellcritical-Myeloid-pDC|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

CXCR3 SCAMP5 FAM3C FKBP2 MFSD3

8.06e-0518510654a5d1d0a757f1f4fdb911be96ed90b52182c25f0
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_adventitial_fibro_(9)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

RELN DGKB MDK PLAT C7

8.27e-0518610658915436d09775f2828a7678af203b1082b36e21c
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ALDH8A1 DGKB SLC13A3 MST1 TTC38

8.27e-051861065a417e1e21313a7e05951038cdef5ac672a9f727c
ToppCell11.5-Airway-Immune-Hematopoietic,_Natural_Killer_Cell|Airway / Age, Tissue, Lineage and Cell class

CXCR3 ARHGAP30 TKTL1 LIM2 CD3E

8.48e-051871065bebb56d31a1df678d85a29931a2ec585549ac122
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_mesothelial_(19)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

VWC2 THSD7B MST1 NELL2 KLK8

8.70e-0518810659655a4c47b644a870017d349b99063e17dbae572
ToppCellwk_08-11-Hematologic_Lymphocytic-NK-Intermediate_NK|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

CXCR3 ARHGAP30 TKTL1 LIM2 CD3E

8.70e-051881065a8170e4ce6406af9f5ad5317e6e26efa7bc66411
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c07-TYROBP|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

TKTL1 CD3E DGKI DTHD1 TTC38

8.92e-051891065bed43041e6f8ba19787150a6aaa492f2656135d9
ToppCellT_cells-GZMK+_CD8+_T_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

CXCR3 TTC24 DGKH CD3E DTHD1

8.92e-051891065e2ca075aedf7c370ab4ede6272254ffd06cbcdec
ToppCell(1)_T_CD8_gd|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)

DGKZ DGKH CD3E DTHD1 TTC38

8.92e-05189106562eda4bcfd21d5025ac676d524994ede22721c1d
ToppCellwk_08-11-Hematologic_Lymphocytic-NK|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

CXCR3 ARHGAP30 TKTL1 APOBR CD3E

9.14e-05190106586b0d142b7d1a3b35580edd104f947106be2c9c6
ToppCell10x5'-blood-Lymphocytic_T_CD8-Trm/em_CD8|blood / Manually curated celltypes from each tissue

CXCR3 TTC24 NELL2 CD3E DTHD1

9.14e-051901065e1f474dc36bf9eaf457b14a8761d287904754cdc
ToppCellBL-critical-LOC-Epithelial-Secretory|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

KLK12 MDK TLE2 KLK8 MUC5AC

9.14e-051901065f2abe4bc28e934287e2dcd7b9399d5af78c5c8cf
ToppCell3'-GW_trimst-1-SmallIntestine-Hematopoietic-T_cells-NK_cell|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CXCR3 ARHGAP30 LIM2 CD3E DTHD1

9.37e-051911065a467205078bec92562e4b6b1b2116b88f421e8ba
ToppCelldroplet-Marrow-BM-30m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC25A21 CEP76 CPOX CD19 TOP2A

9.37e-05191106508be56a4055a73c920d345fd3b2052a5ccb675d8
ToppCell10x5'v1-week_14-16-Lymphocytic_NK-T_NK-mature_NK|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

TKTL1 LIM2 CD3E DTHD1 TTC38

9.60e-051921065e48bbcb97c113f323ad4db96bd10d593b9206923
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

GPD1 ALDH8A1 SLC13A3 MST1 TTC38

9.60e-0519210653e1a4cb0d83efd502c8613d41a1692bdda5860ed
ToppCellnormal_Pleural_Fluid-T/NK_cells-Naive_CD8+_T|normal_Pleural_Fluid / Location, Cell class and cell subclass

CXCR3 NELL2 CD3E DTHD1 TTC38

9.84e-051931065828f11c9081df74faf3b788456991e1a0cf99900
ToppCellfacs-Marrow-B-cells-3m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPD1L P2RX3 CD19 FAM3C TOP2B

9.84e-05193106524c34c6635eb7fc2878282803c421b64320e77d8
ToppCell10x5'v1-week_14-16-Lymphocytic_NK-T_NK-CD56_bright_NK|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

CXCR3 TKTL1 CD3E DTHD1 TTC38

9.84e-05193106546f94a1062b098205e8ce3ed380c0202a4d97678
ToppCelldroplet-Lung-nan-21m-Mesenchymal-adventitial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWC2 SLC25A21 EFS NELL2 PLAT

1.01e-04194106595dfbd9d9b8a47801edcfc35fb0d685901dcd2f8
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

VWC2 RELN THSD7B PAPSS2 TLE2

1.01e-0419410656ac759828c41ffa974ee82842162caa959351dd1
ToppCelldroplet-Lung-nan-21m-Mesenchymal-Adventitial_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWC2 SLC25A21 EFS NELL2 PLAT

1.01e-0419410652507f6dc7f1fe8b91fe1e24497d26d05afc3cd21
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

VWC2 RELN THSD7B PAPSS2 TLE2

1.01e-0419410655d0b0d8e96f0e0297a4dba70a05d87081a4eb323
ToppCellwk_15-18-Hematologic_Lymphocytic-NK-CD16+_NK|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

ARHGAP30 TKTL1 LIM2 CD3E TTC38

1.03e-041951065eadc2f8dd16d2b76c59b85f72905bd4b1545b560
ToppCellT_cells-GZMK+_T_cells|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

CXCR3 ARHGAP30 NELL2 CD3E DTHD1

1.06e-041961065fa5c7fec9e0dcd7e62ff64704bfdf2a3437a43ba
ToppCellproximal-Hematologic-CD8+_Memory/Effector_T|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CXCR3 DGKZ ARHGAP30 CD3E DTHD1

1.06e-041961065096296e3915422b674e043deac633c6b606e415e
ToppCellproximal-Hematologic-CD8+_Memory/Effector_T-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CXCR3 DGKZ ARHGAP30 CD3E DTHD1

1.06e-041961065061712aea24d7e20cd813ef290b430a7042fcb79
ToppCellTracheal-10x3prime_v2-Immune_Lymphocytic-T-T_CD4-T_reg|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

CXCR3 ARHGAP30 CD3E ADGRF3 TOP2A

1.06e-0419610656362fb0b5dc923f19a76b605d7289a16f89220e3
ToppCellproximal-3-Hematologic-CD8+_Memory/Effector_T|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CXCR3 DGKZ ARHGAP30 CD3E DTHD1

1.06e-04196106509e5920112337b0718584b252bb331e2247ef215
DrugAC1L4Q08

DGKB DGKG DGKZ DGKE DGKH DGKI

3.58e-11151036CID000161747
Drug1,2-dicaprin

SLC25A21 DGKB DGKG DGKZ DGKE DGKH PRKD3 DGKI

5.15e-11491038CID000001321
Drug1-stearoyl-2-arachidonoyl-sn-glycerol

DGKB DGKG DGKZ DGKE DGKH PRKD3 DGKI

5.20e-10401037CID000001398
DrugC-1b

DGKB DGKG DGKZ DGKE DGKH PRKD3 DGKI TOP2B

1.25e-09721038CID006102740
Drugdiradylglycerol

DGKB DGKG DGKZ DGKE DGKH PRKD3 DGKI

3.10e-09511037CID006437874
DrugDiC8

SLC25A21 DGKB DGKG DGKZ DGKE DGKH PRKD3 DGKI PLAT

2.15e-081461039CID000001323
DrugR59949

DGKB DGKG DGKZ DGKE DGKH PRKD3 DGKI

2.99e-08701037CID000657356
DrugR59022

DGKB DGKG DGKZ DGKE DGKH PRKD3 DGKI

5.34e-08761037CID000003012
DrugAC1L1BDQ

SLC25A21 DGKB DGKG DGKZ DGKE DGKH PRKD3 EYS DGKI

9.32e-081731039CID000001394
Drug(S)-1,2-Diolein

DGKB DGKG DGKZ DGKE PRKD3 DGKI

1.00e-07501036CID000001324
Drugmonoelaidin

DGKB DGKG DGKZ DGKE DGKH DGKI

1.00e-07501036CID000033022
Drug1,3-diolein

DGKB DGKG DGKZ DGKE DGKH PRKD3 DGKI

1.73e-07901037CID000033120
DrugC-1A

DGKB DGKG DGKZ DGKE DGKH PRKD3 DGKI

1.87e-07911037CID009543473
Drug1,3-DCG

DGKB DGKG DGKZ DGKE DGKH PRKD3 DGKI

2.34e-07941037CID000150911
Drugvitamin E

DGKB DGKG DGKZ DGKE DGKH PAPSS2 PAPSS1 APOBR PRKD3 EYS DGKI PLAT

7.48e-0744110312CID000002116
DrugRHC 80267

DGKB DGKG DGKZ DGKE DGKH PRKD3 DGKI

7.75e-071121037CID000005063
Drugoctylglucopyranoside

DGKB DGKG DGKZ DGKE DGKH LIM2 P2RX3 DGKI

7.76e-071631038CID000062080
DrugPOPC

DGKB DGKG DGKZ DGKE DGKH CPOX PRKD3 SCAP DGKI

1.06e-053061039CID000065167
Drug1-(5-isoquinolinesulfonyl)-2-methylpiperazine

SLC25A21 DGKB DGKG DGKZ DGKE DGKH PRKD3 DGKI PLAT

1.30e-053141039CID000003542
Drug1,2-diglyceride

DGKB DGKG DGKZ DGKE DGKH PRKD3 DGKI

1.50e-051751037CID000192866
DrugCortisporin

DGKB DGKG DGKZ DGKE PRKD3 RBM6 DGKI

1.61e-051771037CID000004454
DrugPDBu

DGKB DGKG DGKZ DGKE DGKH PRKD3 DGKI PLAT

1.78e-052491038CID000037783
DrugDexrazoxane

TOP2A TOP2B

2.03e-0521032DB00380
Drugadenosine 5'-phosphoselenate

PAPSS2 PAPSS1

2.03e-0521032CID000440758
DrugF14512

TOP2A TOP2B

2.03e-0521032ctd:C534191
DrugDaunorubicin

TOP2A TOP2B

2.03e-0521032DB00694
DrugPrenisteine

PCYOX1L PCYOX1

2.03e-0521032CID000021359
DrugK175

F12 PLAT

2.03e-0521032CID005353473
Drugbeta-methylene-APS

PAPSS2 PAPSS1

2.03e-0521032CID000129324
DrugGlafenine hydrochloride [65513-72-6]; Down 200; 9.8uM; HL60; HT_HG-U133A

CXCR3 TNRC6B IL17RC ALPK1 APOBR TTC38 PCYOX1

3.21e-0519710372387_DN
DrugAC1OAGGW

DGKB DGKG DGKZ DGKE DGKH PRKD3 DGKI

3.88e-052031037CID006857364
Drug(2S,3R)-Sphingosine

SLC25A21 DGKB DGKG DGKZ DGKE DGKH PRKD3 DGKI PLAT

6.90e-053891039CID000001104
Drug9-aa-4-ca

PLAT TOP2B

1.21e-0441032CID000129485
Diseasecongenital dyserythropoietic anemia type II (implicated_via_orthology)

SEC23B SEC23A

1.21e-0521032DOID:0111401 (implicated_via_orthology)
Diseasecraniolenticulosutural dysplasia (implicated_via_orthology)

SEC23B SEC23A

1.21e-0521032DOID:0070307 (implicated_via_orthology)
DiseaseB cell deficiency (implicated_via_orthology)

TOP2A TOP2B

1.21e-0521032DOID:2115 (implicated_via_orthology)
DiseaseRoberts syndrome (implicated_via_orthology)

SEC23B SEC23A

7.21e-0541032DOID:5325 (implicated_via_orthology)
Diseasethioredoxin domain-containing protein 12 measurement

MST1 SCAP RBM6

3.45e-04391033EFO_0008298
DiseaseNodular glomerulosclerosis

DGKH ALPK1 MDK

4.00e-04411033C0017667
Diseasekallikrein-11 measurement

KLK12 KLK8

4.28e-0491032EFO_0010573
DiseaseDiabetic Nephropathy

DGKH ALPK1 MDK

4.93e-04441033C0011881
Diseasecomparative body size at age 10, self-reported

GPD1 RELN MCMBP TNRC6B DGKZ DGKH LEPROT

6.91e-044201037EFO_0009819
Diseaseacute myeloid leukemia (implicated_via_orthology)

TOP2A TOP2B

7.78e-04121032DOID:9119 (implicated_via_orthology)
DiseaseThromboembolism

F12 PLAT

7.78e-04121032C0040038
Diseasekallikrein-12 measurement

KLK12 C7

9.18e-04131032EFO_0008194
DiseaseFVC change measurement, response to placebo

RELN DGKB

9.18e-04131032EFO_0008344, EFO_0010339
Diseaseneutrophil percentage of leukocytes

TNRC6B ARHGEF18 DGKH PRKD3 LIM2 LEPROT DTHD1 TOP2A

1.36e-036101038EFO_0007990
Diseasephosphatidylcholine 38:6 measurement

SLC25A21 CPOX

1.40e-03161032EFO_0010388
Diseaseresponse to acetylsalicylate

SLC25A21 SCAP

1.40e-03161032GO_1903492
Diseasenasopharyngeal neoplasm

DGKB EYS GALNT17 ADGRA3

1.97e-031511034EFO_0004252
Diseasefumarate measurement

SLC13A3 EYS

2.43e-03211032EFO_0010480
Diseaseinflammatory bowel disease (implicated_via_orthology)

MST1 MST1L

3.44e-03251032DOID:0050589 (implicated_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
QWVFGSGLCKVAGAL

CXCR3

116

P49682
SLFQGRGGWSKEGCQ

ADGRF3

721

Q8IZF5
LAEGAQIWCGEGVDK

ALDH8A1

346

Q9H2A2
NLPGGGLKTWTQGCL

ARHGEF18

116

Q6ZSZ5
FDLLNGQGGWKSDGC

ADGRA3

706

Q8IWK6
AVGWAGNGILCGRDT

COMP

256

P49747
CLAQVQWAGGGDSDK

FAM220BP

11

B1ANY3
ALPGAWVKGQSAGGC

CAPN10

341

Q9HC96
GGGKQEQWCTLLAFL

CEP76

356

Q8TAP6
LQQRGCWAGKAALGL

DGCR6

186

Q14129
VDLQGWVTGNGKGLI

ALPK1

1176

Q96QP1
IAGGGDVTAKNIWLA

INTS3

171

Q68E01
KLWCAVGVNLSGGKT

SPAG9

686

O60271
LGFRDNWVFCGGKGI

FAM3C

176

Q92520
EGWGLQGLNKGLTAT

SLC25A21

161

Q9BQT8
RGCTVWLTGLSGAGK

PAPSS2

41

O95340
CAEIAIGCWLGGLAG

OR6N1

141

Q8NGY5
VAVIKWGACGLVLAG

LEPROT

91

O15243
GGGLFCAWVGTILLV

LIM2

6

P55344
WQLGFAGSEGEKCQG

EYS

481

Q5T1H1
EKKITEGSGGVCWGG

MYCNOS

16

P40205
CLIFGLGAVWGLGVD

NELL2

11

Q99435
GTGQVIKGWDQGLLG

FKBP2

81

P26885
GLDQCDGGWLADGSV

HAPLN2

286

Q9GZV7
CGGVLQGLVSWGSVG

KLK12

206

Q9UKR0
CEIAGWGETKGTGND

MST1L

606

Q2TV78
LKVCIVGSGNWGSAV

GPD1L

6

Q8N335
WGACDGGTGTKVRQG

MDK

91

P21741
LGWIGGDSCNLIGSF

SLC66A1

76

Q6ZP29
KGRGGNVWLSPVGCA

HLCS

506

P50747
IDLRCGNQGSGWKAI

DCAF4L2

251

Q8NA75
GLWAVEGGNKLVCSG

PCYOX1

246

Q9UHG3
QGSLWSVEGGNKLVC

PCYOX1L

236

Q8NBM8
WGLVRQGLKCEGCGL

PRKD3

176

O94806
GIIGAGVSGLAAIWC

FMO6P

6

O60774
ACAAKGVQLGGWRDG

MUC5AC

681

P98088
LVCGGDGSVGWVLSE

DGKH

386

Q86XP1
GLWNGVGAVVCSIAG

MFSD3

251

Q96ES6
WLTVNGGKLSTVCGA

RELN

2531

P78509
KVLGAALAGCELAWG

PLIN1

141

O60240
RGCTVWLTGLSGAGK

PAPSS1

51

O43252
EQGWCKGRLDNGQVG

PACSIN2

461

Q9UNF0
RVLACGGDGTVGWIL

DGKG

486

P49619
GGDGTVGWILDCIDK

DGKG

491

P49619
GQWFLKACGLGEGDT

GBA2

756

Q9HCG7
LFRWNVSDLGGLGCG

CD19

121

P15391
NLRILACGGDGTVGW

DGKI

426

O75912
ACGGDGTVGWILSIL

DGKI

431

O75912
QGDKGIAGCPGAWGQ

COL6A5

1436

A8TX70
LVGNQAGGVDGGWSC

C7

491

P10643
VLACGGDGTVGWVLD

DGKB

491

Q9Y6T7
GGENIELGIKVWLCG

GALNT17

351

Q6IS24
GLCLLSVGVWGQDGN

CD3E

11

P07766
GGLDGWCLCSLHGQQ

EFS

41

O43281
GWCGLDDVVKTIQSG

DTHD1

451

Q6ZMT9
TGSALNCLGAWVKLG

FLVCR2

156

Q9UPI3
VCIVGSGNWGSAIAK

GPD1

6

P21695
SGNWGSAIAKIVGGN

GPD1

11

P21695
VLDLGCGKGGDLLKW

RNMT

201

O43148
LLCGGVLVGGNWVLT

KLK8

56

O60259
SARVLVCGGDGTVGW

DGKE

271

P52429
LRILACGGDGTVGWI

DGKZ

346

Q13574
KCEIAGWGETKGTGN

MST1

601

P26927
VGEKGLWGLINNAGV

DHRS9

101

Q9BPW9
AVGKIFSGLAQCGAW

DNAH10

1866

Q8IVF4
KGCEESGLSVWIGGQ

SLC13A3

441

Q8WWT9
VGCLAWLIGGGGATN

SCAMP5

56

Q8TAC9
GGQDGAICLWDVLTG

SCAP

1136

Q12770
WERKEGGGGISCVLQ

CPOX

181

P36551
LAVLWAGLQCSGGVG

CYB561D2

126

O14569
RGKSWVCLSLGGSGN

IL17RC

86

Q8NAC3
AGSVGGLQWCGEPKR

MCMBP

191

Q9BTE3
GGVLGIKIGWVCDLD

P2RX3

236

P56373
LQLAGSAWACGVLVG

OR10C1

141

Q96KK4
IWKGSGSLEGEAAGC

ARHGAP30

626

Q7Z6I6
MLKLVGGGGGQDWAC

PANK1

1

Q8TE04
VGGTQACEGGWSQGL

NUTM2D

191

Q5VT03
QGIISWGSGCGDRNK

F12

581

P00748
GCVQQATGWRKGTGL

RBM6

1056

P78332
SLAAQKGGLWCFGGN

SERAC1

241

Q96JX3
INGAEGIGTGWACKL

TOP2B

871

Q02880
FWCRGAGKGTELAGV

SLC22A23

126

A1A5C7
ILAGITSWVAGCAGG

OVCH1

251

Q7RTY7
GVNNWLAKGLGACTS

NIF3L1

136

Q9GZT8
NEIGTGGTCQWKICG

SEC23A

436

Q15436
GVGGTSQWKICGLDP

SEC23B

441

Q15437
QTSCGLLGVEWGGLT

APOBR

541

Q0VD83
CHAQKIGIVGFCWGG

CMBL

121

Q96DG6
GAEDLQVILEKGWCG

UFSP2

431

Q9NUQ7
AWVSQGGGAKAGDLQ

VWC2

96

Q2TAL6
WAVGAVSELRCKGSG

WDR90

1366

Q96KV7
TLVGIISWGLGCGQK

PLAT

526

P00750
ISWGLGCGQKDVPGV

PLAT

531

P00750
SGDMKGQWQACEGLG

TTC24

346

A2A3L6
LVGIVSWGDGCGKKN

TMPRSS11B

381

Q86T26
ISGQCGAGNNWAKGR

TUBB8B

91

A6NNZ2
WCQGLEGGKTRCLGR

NDST2

816

P52849
SIICKQLGCGVWGVG

SCART1

696

Q4G0T1
QLGCGVWGVGLAGEQ

SCART1

701

Q4G0T1
NGAEGIGTGWSCKIP

TOP2A

851

P11388
WTNDKSLGGIEGCLS

TTC38

41

Q5R3I4
GVRVLGKCQDGWLRG

SH3RF2

406

Q8TEC5
DLWDAIVIGAGIQGC

PIPOX

6

Q9P0Z9
QCGGAALRAVWGGLA

TARBP1

201

Q13395
WQGITGSSEACGKGL

THSD7B

816

Q9C0I4
KGSQIGSCGTGVQWD

LCMT2

401

O60294
ECGKNTESVGQLWLG

TUT7

1226

Q5VYS8
GKGCVKVWDVGQPGA

TLE2

476

Q04725
VATGWLGQGLGVACG

TKTL1

91

P51854
GGNASLASKGGWEDC

TNRC6B

786

Q9UPQ9
GGGAICMELLTKQGW

UBE2Q1

346

Q7Z7E8