Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	-	LRRIQ3 PRAMEF5 FBXL3 NLRC4 NLRP3 AMIGO1 NLRP14 PRAMEF6 LRRC41 AMIGO2	2.54e-05	321	113	10	3.80.10.10
Domain	Znf_C2H2	ZNF346 ZNF273 ZNF507 ZFPM1 ZNF385A ZNF519 ZNF467 ZNF595 ZNF385D ZC3H7A ZNF28 ZNF35 ZNF516 ZBTB40 PLAGL2 ZNF542P	2.71e-05	805	113	16	IPR007087
Domain	ZnF_C2H2	ZNF346 ZNF273 ZNF507 ZFPM1 ZNF385A ZNF519 ZNF467 ZNF595 ZNF385D ZC3H7A ZNF28 ZNF35 ZNF516 ZBTB40 PLAGL2 ZNF542P	2.84e-05	808	113	16	SM00355
Domain	L_dom-like	LRRIQ3 PRAMEF5 FBXL3 NLRC4 NLRP3 AMIGO1 NLRP14 PRAMEF6 LRRC41 AMIGO2	3.05e-05	328	113	10	IPR032675
Domain	AMIGO	AMIGO1 AMIGO2	1.08e-04	3	113	2	IPR031283
Domain	ZF_MATRIN	ZNF346 ZNF385A ZNF385D	1.65e-04	18	113	3	PS50171
Domain	ARM-type_fold	INTS7 CLASP2 APOB LYST ARFGEF3 MROH1 PIK3C3 PDS5A ATM	2.19e-04	339	113	9	IPR016024
Domain	ZINC_FINGER_C2H2_2	ZNF273 ZNF507 ZFPM1 ZNF385A ZNF519 ZNF467 ZNF595 ZC3H7A ZNF28 ZNF35 ZNF516 ZBTB40 PLAGL2 ZNF542P	2.43e-04	775	113	14	PS50157
Domain	ZINC_FINGER_C2H2_1	ZNF273 ZNF507 ZFPM1 ZNF385A ZNF519 ZNF467 ZNF595 ZC3H7A ZNF28 ZNF35 ZNF516 ZBTB40 PLAGL2 ZNF542P	2.50e-04	777	113	14	PS00028
Domain	Znf_C2H2-like	ZNF346 ZNF273 ZNF507 ZFPM1 ZNF385A ZNF519 ZNF467 ZNF385D ZC3H7A ZNF28 ZNF35 ZNF516 ZBTB40 PLAGL2	3.19e-04	796	113	14	IPR015880
Domain	NACHT	NLRC4 NLRP3 NLRP14	3.50e-04	23	113	3	PS50837
Domain	NACHT_NTPase	NLRC4 NLRP3 NLRP14	3.50e-04	23	113	3	IPR007111
Domain	BACK	KBTBD3 KLHL40 BTBD3 KLHL18	4.77e-04	60	113	4	SM00875
Domain	BACK	KBTBD3 KLHL40 BTBD3 KLHL18	5.08e-04	61	113	4	PF07707
Domain	BACK	KBTBD3 KLHL40 BTBD3 KLHL18	5.08e-04	61	113	4	IPR011705
Domain	ZnF_U1	ZNF346 ZNF385A ZNF385D	7.03e-04	29	113	3	SM00451
Domain	Znf_U1	ZNF346 ZNF385A ZNF385D	7.03e-04	29	113	3	IPR003604
Domain	Kelch_1	KBTBD3 KLHL40 ATRNL1 KLHL18	8.57e-04	70	113	4	PF01344
Domain	Kelch_1	KBTBD3 KLHL40 ATRNL1 KLHL18	8.57e-04	70	113	4	IPR006652
Domain	Tetraspanin	TSPAN33 TSPAN31 TSPAN13	9.41e-04	32	113	3	IPR000301
Domain	ResIII	FANCM IFIH1	9.92e-04	8	113	2	PF04851
Domain	Helicase/UvrB_N	FANCM IFIH1	9.92e-04	8	113	2	IPR006935
Domain	zf-C2H2	ZNF273 ZNF507 ZFPM1 ZNF519 ZNF467 ZNF595 ZNF28 ZNF35 ZNF516 ZBTB40 PLAGL2 ZNF542P	9.98e-04	693	113	12	PF00096
Domain	Tetraspannin	TSPAN33 TSPAN31 TSPAN13	1.03e-03	33	113	3	PF00335
Domain	Tetraspanin/Peripherin	TSPAN33 TSPAN31 TSPAN13	1.03e-03	33	113	3	IPR018499
Domain	PH_dom-like	FRMPD1 ARHGEF12 PLEKHS1 LYST OSBPL1A TLN2 VAV3 PREX1 AGAP2	1.13e-03	426	113	9	IPR011993
Domain	BTB	KBTBD3 KLHL40 BTBD3 ZBTB40 KLHL18	1.21e-03	131	113	5	PF00651
Domain	GDS_CDC24_CS	ARHGEF12 VAV3 PREX1	1.68e-03	39	113	3	IPR001331
Domain	BTB-kelch_protein	KBTBD3 KLHL40 KLHL18	2.23e-03	43	113	3	IPR017096
Domain	Znf_C2H2_matrin	ZNF346 ZNF385D	2.30e-03	12	113	2	IPR000690
Domain	-	NLRC4 NLRP3 IFIH1 NLRP14	2.45e-03	93	113	4	1.10.533.10
Domain	BTB	KBTBD3 KLHL40 BTBD3 ZBTB40 KLHL18	2.89e-03	160	113	5	PS50097
Domain	-	KBTBD3 KLHL40 ATRNL1	3.06e-03	48	113	3	2.120.10.80
Domain	DEATH-like_dom	NLRC4 NLRP3 IFIH1 NLRP14	3.08e-03	99	113	4	IPR011029
Domain	PI3/4_kinase_CS	PIK3C3 ATM	3.62e-03	15	113	2	IPR018936
Domain	-	PIK3C3 ATM	4.12e-03	16	113	2	1.10.1070.11
Domain	PI3Kc	PIK3C3 ATM	4.12e-03	16	113	2	SM00146
Domain	Kelch-typ_b-propeller	KBTBD3 KLHL40 ATRNL1	4.50e-03	55	113	3	IPR015915
Domain	BTB	KBTBD3 KLHL40 BTBD3 ZBTB40 KLHL18	4.78e-03	180	113	5	SM00225
Domain	PI3/4_kinase_cat_dom	PIK3C3 ATM	5.21e-03	18	113	2	IPR000403
Domain	PI3_PI4_kinase	PIK3C3 ATM	5.21e-03	18	113	2	PF00454
Domain	PI3_4_KINASE_3	PIK3C3 ATM	5.21e-03	18	113	2	PS50290
Domain	PI3_4_KINASE_1	PIK3C3 ATM	5.21e-03	18	113	2	PS00915
Domain	PI3_4_KINASE_2	PIK3C3 ATM	5.21e-03	18	113	2	PS00916
Domain	Kelch	KBTBD3 KLHL40 KLHL18	5.23e-03	58	113	3	SM00612
Domain	BTB/POZ_dom	KBTBD3 KLHL40 BTBD3 ZBTB40 KLHL18	5.36e-03	185	113	5	IPR000210
Domain	Gal_Oxase/kelch_b-propeller	KBTBD3 KLHL40 KLHL18	5.48e-03	59	113	3	IPR011043
Domain	PRAME_family	PRAMEF5 PRAMEF6	5.80e-03	19	113	2	IPR026271
Domain	SKP1/BTB/POZ	KBTBD3 KLHL40 BTBD3 ZBTB40 KLHL18	5.86e-03	189	113	5	IPR011333
Pubmed	IRF8 Regulates Transcription of Naips for NLRC4 Inflammasome Activation.	NLRC4 NLRP3 IFNAR2 IFIH1	9.91e-07	23	116	4	29576451
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	FKBP15 TMEM94 FRMPD1 ARHGEF12 ARFGEF3 MROH1 STARD9 PCDH19 WDR48	9.54e-06	407	116	9	12693553
Pubmed	Variants in NLRP3 and NLRC4 inflammasome associate with susceptibility and severity of multiple sclerosis.	NLRC4 NLRP3	1.10e-05	2	116	2	30658261
Pubmed	Variation in Niemann-Pick C1-like 1 gene as a determinant of apolipoprotein B-100 kinetics and response to statin therapy in centrally obese men.	APOB NPC1L1	1.10e-05	2	116	2	18031309
Pubmed	Inflammasome-independent NLRP3 function enforces ATM activity in response to genotoxic stress.	NLRP3 ATM	1.10e-05	2	116	2	36746533
Pubmed	Inflammasome Genetic Variants, Macrophage Function, and Clinical Outcomes in Cystic Fibrosis.	NLRC4 NLRP3	1.10e-05	2	116	2	33848452
Pubmed	Leukotriene D4 and prostaglandin E2 signals synergize and potentiate vascular inflammation in a mast cell-dependent manner through cysteinyl leukotriene receptor 1 and E-prostanoid receptor 3.	CYSLTR1 PTGER3	1.10e-05	2	116	2	26255103
Pubmed	The Salmonella pathogenicity island-2 subverts human NLRP3 and NLRC4 inflammasome responses.	NLRC4 NLRP3	1.10e-05	2	116	2	30368901
Pubmed	NLRC4 inflammasome activation is NLRP3- and phosphorylation-independent during infection and does not protect from melanoma.	NLRC4 NLRP3	1.10e-05	2	116	2	32342103
Pubmed	UAF1 deubiquitinase complexes facilitate NLRP3 inflammasome activation by promoting NLRP3 expression.	NLRP3 WDR48	1.10e-05	2	116	2	33247121
Pubmed	Actions of the NLRP3 and NLRC4 inflammasomes overlap in bone resorption.	NLRC4 NLRP3	1.10e-05	2	116	2	34383985
Pubmed	NAIP/NLRC4 inflammasome participates in macrophage responses to Trypanosoma cruzi by a mechanism that relies on cathepsin-dependent caspase-1 cleavage.	NLRC4 NLRP3	1.10e-05	2	116	2	38124741
Pubmed	Flagellin/NLRC4 Pathway Rescues NLRP3-Inflammasome Defect in Dendritic Cells From HIV-Infected Patients: Perspective for New Adjuvant in Immunocompromised Individuals.	NLRC4 NLRP3	1.10e-05	2	116	2	31244842
Pubmed	ZNF385A and ZNF346 Serve as Prognostic Biomarkers Associated with an Inflamed Immunosuppressive Tumor Microenvironment in Hepatocellular Carcinoma.	ZNF346 ZNF385A	1.10e-05	2	116	2	36834567
Pubmed	The transcription factor IRF1 and guanylate-binding proteins target activation of the AIM2 inflammasome by Francisella infection.	NLRC4 NLRP3 IFNAR2	2.38e-05	17	116	3	25774715
Pubmed	Involvement of the AIM2, NLRC4, and NLRP3 inflammasomes in caspase-1 activation by Listeria monocytogenes.	NLRC4 NLRP3	3.30e-05	3	116	2	20490635
Pubmed	Nuclear factor E2-related factor-2 (Nrf2) is required for NLRP3 and AIM2 inflammasome activation.	NLRC4 NLRP3	3.30e-05	3	116	2	24798340
Pubmed	Variation in telangiectasia predisposing genes is associated with overall radiation toxicity.	ACVRL1 ATM	3.30e-05	3	116	2	22677372
Pubmed	Inflammation-induced tumorigenesis in the colon is regulated by caspase-1 and NLRC4.	NLRC4 NLRP3	3.30e-05	3	116	2	21118981
Pubmed	Actin polymerization as a key innate immune effector mechanism to control Salmonella infection.	NLRC4 NLRP3	3.30e-05	3	116	2	25422455
Pubmed	A novel role for the NLRC4 inflammasome in mucosal defenses against the fungal pathogen Candida albicans.	NLRC4 NLRP3	3.30e-05	3	116	2	22174673
Pubmed	Artificial Loading of ASC Specks with Cytosolic Antigens.	NLRC4 NLRP3	3.30e-05	3	116	2	26258904
Pubmed	β-arrestin1 is critical for the full activation of NLRP3 and NLRC4 inflammasomes.	NLRC4 NLRP3	3.30e-05	3	116	2	25582856
Pubmed	AMIGO, a transmembrane protein implicated in axon tract development, defines a novel protein family with leucine-rich repeats.	AMIGO1 AMIGO2	3.30e-05	3	116	2	12629050
Pubmed	Aberrant expression of NLRP3, NLRC4 and NLRP6 inflammasomes in patients with primary immune thrombocytopenia.	NLRC4 NLRP3	3.30e-05	3	116	2	30802690
Pubmed	Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration.	NLRC4 NLRP3	3.30e-05	3	116	2	17599094
Pubmed	Mast cells mediate neutrophil recruitment and vascular leakage through the NLRP3 inflammasome in histamine-independent urticaria.	NLRC4 NLRP3	3.30e-05	3	116	2	19364881
Pubmed	Latent Upregulation of Nlrp3, Nlrc4 and Aim2 Differentiates between Asymptomatic and Symptomatic Trichomonas vaginalis Infection.	NLRC4 NLRP3	3.30e-05	3	116	2	33866944
Pubmed	G Protein signaling modulator-3 inhibits the inflammasome activity of NLRP3.	NLRC4 NLRP3	3.30e-05	3	116	2	25271165
Pubmed	Evaluation of NLRC4, NLRP1, and NLRP3, as Components of Inflammasomes, in Chronic Hepatitis B Virus-Infected Patients.	NLRC4 NLRP3	3.30e-05	3	116	2	27750030
Pubmed	Redundant roles for inflammasome receptors NLRP3 and NLRC4 in host defense against Salmonella.	NLRC4 NLRP3	3.30e-05	3	116	2	20603313
Pubmed	Cutting edge: Candida albicans hyphae formation triggers activation of the Nlrp3 inflammasome.	NLRC4 NLRP3	3.30e-05	3	116	2	19684085
Pubmed	NFκB and NLRP3/NLRC4 inflammasomes regulate differentiation, activation and functional properties of monocytes in response to distinct SARS-CoV-2 proteins.	NLRC4 NLRP3	3.30e-05	3	116	2	38453949
Pubmed	Cutting edge: Necrosis activates the NLRP3 inflammasome.	NLRC4 NLRP3	3.30e-05	3	116	2	19596994
Pubmed	Association of Inflammasome Components in Background Liver with Poor Prognosis After Curatively-resected Hepatocellular Carcinoma.	NLRC4 NLRP3	3.30e-05	3	116	2	28011505
Pubmed	The intracellular sensor NLRP3 mediates key innate and healing responses to influenza A virus via the regulation of caspase-1.	NLRC4 NLRP3	3.30e-05	3	116	2	19362023
Pubmed	A role for mitochondria in NLRP3 inflammasome activation.	NLRC4 NLRP3	3.30e-05	3	116	2	21124315
Pubmed	Appearance of new tetraspanin genes during vertebrate evolution.	TSPAN33 TSPAN31 TSPAN13	3.95e-05	20	116	3	18291621
Pubmed	Bypassing pathogen-induced inflammasome activation for the regulation of interleukin-1beta production by the fungal pathogen Candida albicans.	NLRC4 NLRP3	6.59e-05	4	116	2	19222370
Pubmed	Immune recognition of Pseudomonas aeruginosa mediated by the IPAF/NLRC4 inflammasome.	NLRC4 NLRP3	6.59e-05	4	116	2	18070936
Pubmed	NLRP3 recruitment by NLRC4 during Salmonella infection.	NLRC4 NLRP3	6.59e-05	4	116	2	27139490
Pubmed	Multiple Nod-like receptors activate caspase 1 during Listeria monocytogenes infection.	NLRC4 NLRP3	6.59e-05	4	116	2	18490757
Pubmed	Critical roles of ASC inflammasomes in caspase-1 activation and host innate resistance to Streptococcus pneumoniae infection.	NLRC4 NLRP3	6.59e-05	4	116	2	21957143
Pubmed	Involvement of the NLRP3 inflammasome in innate and humoral adaptive immune responses to fungal beta-glucan.	NLRC4 NLRP3	6.59e-05	4	116	2	20007575
Pubmed	AMIGO1 Promotes Axon Growth and Territory Matching in the Retina.	AMIGO1 AMIGO2	6.59e-05	4	116	2	35169021
Pubmed	Listeria monocytogenes is sensed by the NLRP3 and AIM2 inflammasome.	NLRC4 NLRP3	6.59e-05	4	116	2	20333626
Pubmed	NLRP3 inflammasome mediates interleukin-1β production in immune cells in response to Acinetobacter baumannii and contributes to pulmonary inflammation in mice.	NLRC4 NLRP3	6.59e-05	4	116	2	28032341
Pubmed	Cutting edge: alum adjuvant stimulates inflammatory dendritic cells through activation of the NALP3 inflammasome.	NLRC4 NLRP3	6.59e-05	4	116	2	18768827
Pubmed	Inhibition of inflammasome activation by Coxiella burnetii type IV secretion system effector IcaA.	NLRC4 NLRP3	6.59e-05	4	116	2	26687278
Pubmed	Heterozygous mutation of ataxia-telangiectasia mutated gene aggravates hypercholesterolemia in apoE-deficient mice.	APOB ATM	6.59e-05	4	116	2	15863839
Pubmed	Differential regulation of caspase-1 activation via NLRP3/NLRC4 inflammasomes mediated by aerolysin and type III secretion system during Aeromonas veronii infection.	NLRC4 NLRP3	6.59e-05	4	116	2	21037094
Pubmed	AIM2 and NLRC4 inflammasomes contribute with ASC to acute brain injury independently of NLRP3.	NLRC4 NLRP3	6.59e-05	4	116	2	25775556
Pubmed	The NLRP3 inflammasome functions as a negative regulator of tumorigenesis during colitis-associated cancer.	NLRC4 NLRP3	6.59e-05	4	116	2	20385749
Pubmed	Inflammatory role of ASC in antigen-induced arthritis is independent of caspase-1, NALP-3, and IPAF.	NLRC4 NLRP3	6.59e-05	4	116	2	19717512
Pubmed	Asc and Ipaf Inflammasomes direct distinct pathways for caspase-1 activation in response to Legionella pneumophila.	NLRC4 NLRP3	6.59e-05	4	116	2	19237518
Pubmed	Interleukin-18 diagnostically distinguishes and pathogenically promotes human and murine macrophage activation syndrome.	NLRC4 NLRP3	6.59e-05	4	116	2	29326099
Pubmed	Granuloma formation and host defense in chronic Mycobacterium tuberculosis infection requires PYCARD/ASC but not NLRP3 or caspase-1.	NLRC4 NLRP3	6.59e-05	4	116	2	20808838
Pubmed	The Nlrp3 inflammasome is critical for aluminium hydroxide-mediated IL-1beta secretion but dispensable for adjuvant activity.	NLRC4 NLRP3	6.59e-05	4	116	2	18624356
Pubmed	Radiation causes tissue damage by dysregulating inflammasome-gasdermin D signaling in both host and transplanted cells.	NLRC4 NLRP3	6.59e-05	4	116	2	32760056
Pubmed	Transcript mapping in a 46-kb sequenced region at the core of 12q13.3 amplification in human cancers.	TSPAN31 AGAP2	6.59e-05	4	116	2	9192850
Pubmed	Cutting edge: proteolytic inactivation of poly(ADP-ribose) polymerase 1 by the Nlrp3 and Nlrc4 inflammasomes.	NLRC4 NLRP3	6.59e-05	4	116	2	20713892
Pubmed	Cytotoxins of the human pathogen Aeromonas hydrophila trigger, via the NLRP3 inflammasome, caspase-1 activation in macrophages.	NLRC4 NLRP3	6.59e-05	4	116	2	20722078
Pubmed	Rho GEFs and cancer: linking gene expression and metastatic dissemination.	VAV3 PREX1	6.59e-05	4	116	2	23033535
Pubmed	Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants.	NLRC4 NLRP3	6.59e-05	4	116	2	18496530
Pubmed	Nucleotide-binding and oligomerization domain-like receptors and retinoic acid inducible gene-like receptors in human tonsillar T lymphocytes.	NLRP3 IFIH1	6.59e-05	4	116	2	21342182
Pubmed	TLR agonists stimulate Nlrp3-dependent IL-1β production independently of the purinergic P2X7 receptor in dendritic cells and in vivo.	NLRC4 NLRP3	6.59e-05	4	116	2	23225887
Pubmed	Alivin 1, a novel neuronal activity-dependent gene, inhibits apoptosis and promotes survival of cerebellar granule neurons.	AMIGO1 AMIGO2	6.59e-05	4	116	2	12843293
Pubmed	Disruption of glycolytic flux is a signal for inflammasome signaling and pyroptotic cell death.	NLRC4 NLRP3	6.59e-05	4	116	2	27011353
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	PRAMEF5 DDX49 PDCD6IP FRMPD1 ZNF507 CLASP2 APOB ZNF595 AP4S1 ATRNL1 ZBTB40 EIF2AK4 PRAMEF6	6.92e-05	1084	116	13	11544199
Pubmed	Microarray analysis of Foxa2 mutant mouse embryos reveals novel gene expression and inductive roles for the gastrula organizer and its derivatives.	RO60 TSPAN33 AP4S1 PCDH19 PLAGL2 ATM PREX1	7.84e-05	306	116	7	18973680
Pubmed	ZBP1/DAI is an innate sensor of influenza virus triggering the NLRP3 inflammasome and programmed cell death pathways.	NLRC4 NLRP3 IFNAR2	7.88e-05	25	116	3	27917412
Pubmed	Targeted peptidecentric proteomics reveals caspase-7 as a substrate of the caspase-1 inflammasomes.	NLRC4 NLRP3	1.10e-04	5	116	2	18667412
Pubmed	Kv2 channel-AMIGO β-subunit assembly modulates both channel function and cell adhesion molecule surface trafficking.	AMIGO1 AMIGO2	1.10e-04	5	116	2	34137443
Pubmed	Critical role for Ipaf in Pseudomonas aeruginosa-induced caspase-1 activation.	NLRC4 NLRP3	1.10e-04	5	116	2	17935074
Pubmed	Activation of the Nlrp3 inflammasome by Streptococcus pyogenes requires streptolysin O and NF-kappa B activation but proceeds independently of TLR signaling and P2X7 receptor.	NLRC4 NLRP3	1.10e-04	5	116	2	19812205
Pubmed	DDX17 is an essential mediator of sterile NLRC4 inflammasome activation by retrotransposon RNAs.	NLRC4 NLRP3	1.10e-04	5	116	2	34860583
Pubmed	Obesity-associated NLRC4 inflammasome activation drives breast cancer progression.	NLRC4 NLRP3	1.10e-04	5	116	2	27708283
Pubmed	Toll-like receptor and inflammasome signals converge to amplify the innate bactericidal capacity of T helper 1 cells.	NLRC4 NLRP3	1.10e-04	5	116	2	24508233
Pubmed	Cryopyrin activates the inflammasome in response to toxins and ATP.	NLRC4 NLRP3	1.10e-04	5	116	2	16407890
Pubmed	Necrotic cells trigger a sterile inflammatory response through the Nlrp3 inflammasome.	NLRC4 NLRP3	1.10e-04	5	116	2	19918053
Pubmed	Role of the caspase-1 inflammasome in Salmonella typhimurium pathogenesis.	NLRC4 NLRP3	1.10e-04	5	116	2	16717117
Pubmed	Cytosolic flagellin-induced lysosomal pathway regulates inflammasome-dependent and -independent macrophage responses.	NLRC4 NLRP3	1.10e-04	5	116	2	23942123
Pubmed	Nanoparticles activate the NLR pyrin domain containing 3 (Nlrp3) inflammasome and cause pulmonary inflammation through release of IL-1α and IL-1β.	NLRC4 NLRP3	1.10e-04	5	116	2	20974980
Pubmed	Salmonella enterica Serovar Typhimurium Induces NAIP/NLRC4- and NLRP3/ASC-Independent, Caspase-4-Dependent Inflammasome Activation in Human Intestinal Epithelial Cells.	NLRC4 NLRP3	1.10e-04	5	116	2	35678562
Pubmed	Polymorphisms in ACE1, TMPRSS2, IFIH1, IFNAR2, and TYK2 Genes Are Associated with Worse Clinical Outcomes in COVID-19.	IFNAR2 IFIH1	1.10e-04	5	116	2	36672770
Pubmed	RNF123 has an E3 ligase-independent function in RIG-I-like receptor-mediated antiviral signaling.	IFIH1 RNF123	1.10e-04	5	116	2	27312109
Pubmed	Arsenic trioxide and other arsenical compounds inhibit the NLRP1, NLRP3, and NAIP5/NLRC4 inflammasomes.	NLRC4 NLRP3	1.10e-04	5	116	2	24337744
Pubmed	Differential requirement of P2X7 receptor and intracellular K+ for caspase-1 activation induced by intracellular and extracellular bacteria.	NLRC4 NLRP3	1.10e-04	5	116	2	17491021
Pubmed	Inflammasome recognition of influenza virus is essential for adaptive immune responses.	NLRC4 NLRP3	1.10e-04	5	116	2	19139171
Pubmed	CARD9 negatively regulates NLRP3-induced IL-1β production on Salmonella infection of macrophages.	NLRC4 NLRP3	1.10e-04	5	116	2	27670879
Pubmed	The inflammasome recognizes cytosolic microbial and host DNA and triggers an innate immune response.	NLRC4 NLRP3	1.10e-04	5	116	2	18288107
Pubmed	Inflammasome activation causes dual recruitment of NLRC4 and NLRP3 to the same macromolecular complex.	NLRC4 NLRP3	1.10e-04	5	116	2	24803432
Pubmed	NLRP3 (NALP3, Cryopyrin) facilitates in vivo caspase-1 activation, necrosis, and HMGB1 release via inflammasome-dependent and -independent pathways.	NLRC4 NLRP3	1.10e-04	5	116	2	19587006
Pubmed	NLRP3 selectively drives IL-1β secretion by Pseudomonas aeruginosa infected neutrophils and regulates corneal disease severity.	NLRC4 NLRP3	1.10e-04	5	116	2	37730693
Pubmed	Cathepsin-mediated necrosis controls the adaptive immune response by Th2 (T helper type 2)-associated adjuvants.	NLRC4 NLRP3	1.10e-04	5	116	2	23297415
Pubmed	IL-1 receptor antagonist ameliorates inflammasome-dependent inflammation in murine and human cystic fibrosis.	NLRC4 NLRP3	1.10e-04	5	116	2	26972847
Pubmed	NOD-like receptors and RIG-I-like receptors in human eosinophils: activation by NOD1 and NOD2 agonists.	NLRP3 IFIH1	1.10e-04	5	116	2	21978001
Pubmed	The NLRP3 inflammasome mediates in vivo innate immunity to influenza A virus through recognition of viral RNA.	NLRC4 NLRP3	1.10e-04	5	116	2	19362020
Pubmed	Significant role of IL-1 signaling, but limited role of inflammasome activation, in oviduct pathology during Chlamydia muridarum genital infection.	NLRC4 NLRP3	1.10e-04	5	116	2	22331066
Pubmed	IL-1β signaling promotes CNS-intrinsic immune control of West Nile virus infection.	NLRC4 NLRP3	1.10e-04	5	116	2	23209411
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF273 ZNF507 ZFPM1 ZNF519 ZNF467 ZNF595 ZNF28 ZNF35 ZNF516 ZBTB40 PLAGL2 ZNF542P	1.45e-04	718	86	12	28
GeneFamily	NLR family	NLRC4 NLRP3 NLRP14	2.22e-04	25	86	3	666
GeneFamily	Basic leucine zipper proteins\|BTB domain containing	KBTBD3 KLHL40 BTBD3 ZBTB40 KLHL18	4.47e-04	134	86	5	861
GeneFamily	CD molecules\|Tetraspanins	TSPAN33 TSPAN31 TSPAN13	5.11e-04	33	86	3	768
GeneFamily	X-linked mental retardation\|RNA helicases	FANCM IFIH1	1.20e-03	11	86	2	1168
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	ARHGEF12 VAV3 PREX1	3.83e-03	66	86	3	722
ToppCell	Ciliated_cells-B-Donor_08\|World / lung cells shred on cell class, cell subclass, sample id	LRRIQ3 CFAP54 DNAH12 MAPK15 BBS12 CLBA1	4.89e-06	166	116	6	4b1056aad8a99827835242b8ab0c7f2bb84471f1
ToppCell	facs-Aorta-Heart-3m-Endothelial-endocardial_endothelial_cells\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZNF507 SCX BTBD3 MAPK15 OTOGL AMIGO2	5.06e-06	167	116	6	a4a795751644b22af616335379e64ae95175180c
ToppCell	CD8+_Memory_T_cell-FLU-3\|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster	LRRIQ3 ZNF507 NLRP3 CFAP54 ADGRF3 WDR62	5.99e-06	172	116	6	45ac433dbb3796f69e886c04457b2971403050ee
ToppCell	FLU-Healthy-3\|FLU / Virus stimulation, Condition and Cluster	LRRIQ3 ZNF507 NLRP3 CFAP54 ADGRF3 WDR62	6.20e-06	173	116	6	32b8e5b400885dbeba57a7cb2c18d882664dc285
ToppCell	FLU-Healthy-3\|Healthy / Virus stimulation, Condition and Cluster	LRRIQ3 ZNF507 NLRP3 CFAP54 ADGRF3 WDR62	6.20e-06	173	116	6	26e89ac86922f1cd0100cf4d1cce37e74dd31c88
ToppCell	Bronchial-NucSeq-Immune_Lymphocytic-NK-ILC-T_NK\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ZFPM1 TXK CCL3 VAV3 ATM PREX1	1.41e-05	200	116	6	7eed3d932018d6a87ce37d013883b371db55caeb
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Alv_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	ARHGEF12 ACVRL1 LUZP1 BTBD3 OSBPL1A PREX1	1.41e-05	200	116	6	7034f57e282982c19c13ee8ab78eabaffa069e30
ToppCell	Bronchial-NucSeq-Immune_Lymphocytic-NK-ILC\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ZFPM1 TXK CCL3 VAV3 ATM PREX1	1.41e-05	200	116	6	56d738ff019682af7f1f8cbe7b262a75dc8596d5
ToppCell	Bronchial-NucSeq-Immune_Lymphocytic-NK-ILC-T_NK-NK\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ZFPM1 TXK CCL3 VAV3 ATM PREX1	1.41e-05	200	116	6	0f8e2fed93cc103b20a825d8d3e83787c5c015cc
ToppCell	Control_saline-Endothelial-Endothelial-Alv_Cap\|Control_saline / Treatment groups by lineage, cell group, cell type	ARHGEF12 ACVRL1 LUZP1 BTBD3 VAV3 AMIGO2	1.41e-05	200	116	6	abf4ba5fcb54cdeada0da1a8b956a30aa47679e4
ToppCell	368C-Fibroblasts-Fibroblast-E\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	KBTBD3 IFIH1 NLRP14 PLD5 WDR62	4.59e-05	150	116	5	c3ad5fa41eb636a5d691c0268c0f1c32cd0de658
ToppCell	368C-Fibroblasts-Fibroblast-E-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	KBTBD3 IFIH1 NLRP14 PLD5 WDR62	4.59e-05	150	116	5	78b8029e71d26f336a46274c8afef3435bf536b9
ToppCell	Ciliated_cells-A-IPF_02\|World / lung cells shred on cell class, cell subclass, sample id	PLEKHS1 CFAP54 DNAH12 MAPK15 AGBL2	4.74e-05	151	116	5	9d03ce73af15ef40c592d19b36aff46bebc14c40
ToppCell	TCGA-Uterus-Primary_Tumor-Uterine_Carcinoma-Uterine_Carcinosarcoma\|TCGA-Uterus / Sample_Type by Project: Shred V9	RO60 LYST ARFGEF3 ZNF28 TSPAN13	4.74e-05	151	116	5	2810bfa01bd3016aeba29735eb4a9284792e8aac
ToppCell	facs-Liver-Non-hepatocytes-3m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NLRC4 NLRP3 CCL3 EIF2AK4 KLHL18	4.89e-05	152	116	5	b61d2f6ee819c8dd4b4b601a8bc8388b1983de58
ToppCell	facs-Lung-EPCAM-3m-Lymphocytic-NK_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TXK SLC44A5 POLI CCL3 PREX1	5.04e-05	153	116	5	2a94092937267cd2282452dfde3d328d763d4294
ToppCell	facs-Lung-EPCAM-3m-Lymphocytic-Natural_Killer\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TXK SLC44A5 POLI CCL3 PREX1	5.04e-05	153	116	5	ad33c81fe6ac10e7c263d42541aae0d796923bad
ToppCell	droplet-Lung-nan-3m-Myeloid-Proliferating_Dendritic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYSLTR1 PTGER3 TSPAN33 SPRING1 MED12L	6.23e-05	160	116	5	8a7a73b0ee1877fe02d47f745d36ae2858b529e1
ToppCell	facs-GAT-Fat-24m-Lymphocytic-NK_cell\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	C16orf96 TXK MED12L CCL3 AGAP2	6.81e-05	163	116	5	e58863a462cc504bced627f004a47890ee2307ce
ToppCell	LPS-antiTNF-Epithelial_airway\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	VTCN1 PLEKHS1 ARFGEF3 MAPK15 PLD5	7.42e-05	166	116	5	eb942ed68677e55c46cb039046f45686d4062d7c
ToppCell	Posterior_cortex-Neuronal-Inhibitory\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	ZNF385A SCX ANKRD34B SLC44A5 PLD5	7.63e-05	167	116	5	9a84f45345c75f2c8ff38a04245aadee2a26a240
ToppCell	Control-NK\|Control / Disease group and Cell class	CYSLTR1 TXK MMRN1 ZNF516 TSPAN13	7.85e-05	168	116	5	683d389c8a1e791bfc773e63148115a21a6566db
ToppCell	Hippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	RO60 ZNF385A SCX ANKRD34B PLD5	8.07e-05	169	116	5	c135d7ae0490d0024e0f4bd8c4ad42f6674a61da
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ZNF273 CFAP54 DNAH12 MAPK15 AGBL2	8.07e-05	169	116	5	14aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCell	facs-Brain_Non-Myeloid-Striatum_-18m-Macroglial-astrocyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	C16orf96 AP4S1 MROH1 ZNF35 ZBTB40	8.77e-05	172	116	5	e15ab284df6dd241d4481f98864b18c39d757b8c
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_SEMA6D\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PLEKHS1 TSPAN33 OTOGL MED12L ROS1	9.01e-05	173	116	5	9a2d42f8d9cb834856522661d524abb91c4637c5
ToppCell	ASK452-Endothelial-Lymphatic\|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq	ZNF595 BTBD3 MMRN1 STARD9 KLHL18	9.77e-05	176	116	5	b4d280ecc07701d526f50d44c45ea91b3eeb00b1
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_STON2\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FRMPD1 ZNF385D ANKRD34B VAV3 PLD5	1.06e-04	179	116	5	d1365d48d1b017a7917f4f63a82ac4720c3d87df
ToppCell	E16.5-samps-Endothelial-Immature_fetal_endothelial-Proliferative_Endothelial\|E16.5-samps / Age Group, Lineage, Cell class and subclass	ACVRL1 BTBD3 MMRN1 TSPAN13 VAV3	1.06e-04	179	116	5	d24513a404c9b1d37dd47aa1cdb5713b64b88f89
ToppCell	PND01-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_G2M\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NUP205 MMRN1 ATRNL1 PLD5 WDR62	1.06e-04	179	116	5	df4d0b2fe47d2c7def729b3217cb01ced01495ff
ToppCell	Control-Epithelial_cells-Airway_ciliated\|Control / group, cell type (main and fine annotations)	ZNF273 PLEKHS1 CFAP54 DNAH12 AGBL2	1.14e-04	182	116	5	fb725d10d9ed25dfc6d5bb69cfef78513f7d3e8f
ToppCell	Hippocampus-Neuronal-Inhibitory\|Hippocampus / BrainAtlas - Mouse McCarroll V32	RO60 ZNF385A SCX ANKRD34B PLD5	1.14e-04	182	116	5	b54ae650c04dfd0759c5f5e752b9bf684dd36516
ToppCell	367C-Myeloid-Dendritic-cDC1\|367C / Donor, Lineage, Cell class and subclass (all cells)	ZNF467 PTGER3 NLRP3 TSPAN33 VAV3	1.14e-04	182	116	5	6f5228ac47f9ab46d165740cf2655b5ba217acbe
ToppCell	Control-APC-like-Dendritic_cells\|Control / group, cell type (main and fine annotations)	NLRP3 TSPAN33 MED12L VAV3 PREX1	1.17e-04	183	116	5	8f9c8e2436f18ea7c265b08e4e149e19cb513a16
ToppCell	Control-APC-like\|Control / group, cell type (main and fine annotations)	NLRP3 TSPAN33 MED12L VAV3 PREX1	1.17e-04	183	116	5	c313ac72cc9fa1583456d452393f61f0a4ca33a8
ToppCell	(4)_B_cells-(4)_B_mantle\|(4)_B_cells / Spleen cell shreds - cell class (v1) and cell subclass (v1)	LYST MMRN1 TSPAN13 CCL3 VAV3	1.17e-04	183	116	5	21b7fb6482eb1d5d31a4029e47e0992e8ddc8e2c
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Endothelial-leukocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HTR2B MMRN1 AJAP1 POLI PLD5	1.17e-04	183	116	5	919c9861073d12fd12aecd7469b1478b13838c43
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	APOB ARFGEF3 OTOGL TLN2 ROS1	1.20e-04	184	116	5	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	APOB ARFGEF3 OTOGL TLN2 ROS1	1.20e-04	184	116	5	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	APOB ARFGEF3 OTOGL TLN2 ROS1	1.20e-04	184	116	5	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	Ciliated_cells-B-Myositis-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	PLEKHS1 CFAP54 DNAH12 MAPK15 AGBL2	1.23e-04	185	116	5	f012c243343e1d1956db19b34d062e9b13de2b2a
ToppCell	Adult-Epithelial-ciliated_cell-D175\|Adult / Lineage, Cell type, age group and donor	ZNF273 CFAP54 DNAH12 MAPK15 AGBL2	1.23e-04	185	116	5	30f4980dee6cd5959655f8d74049f3bfb5312611
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_STON2\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FRMPD1 ZNF385D ANKRD34B VAV3 PLD5	1.23e-04	185	116	5	f4ac62009c0ad3346e71b809e17727303c4df153
ToppCell	Control-Endothelial-Endothelial-Alv_Cap\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ACVRL1 LUZP1 BTBD3 IFNAR2 VAV3	1.30e-04	187	116	5	ea9d34bcd3bd1f36745846309ede349773de501a
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PTGER3 F11 TSPAN33 ARFGEF3 ZNF385D	1.30e-04	187	116	5	85e58a312fc325e4063a2d250666b99b8f99beb6
ToppCell	Fetal_29-31_weeks-Immune-natural_killer_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ZFPM1 LYST TXK CCL3 VAV3	1.33e-04	188	116	5	6686dbba990066568aa7573e70a7db8b4758f457
ToppCell	Endothelial-B-IPF_03\|World / lung cells shred on cell class, cell subclass, sample id	ORC6 ZNF467 MMRN1 ZNF385D ZNF35	1.33e-04	188	116	5	ecb74d67314a43b5805b7f2a7bb9ff6c5a60200a
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L3-4_PVALB_HOMER3\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ZNF385A ZNF385D ANKRD34B VAV3 PLD5	1.33e-04	188	116	5	72cbfe9dc0583dbeafa6cb0945fa370d0c808284
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ZNF385A ZNF385D ANKRD34B VAV3 PLD5	1.33e-04	188	116	5	8de5a07301f9b5984680c873e5a92395b5ed3dd3
ToppCell	PND01-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	C16orf96 CFAP54 DNAH12 MAPK15 AGBL2	1.36e-04	189	116	5	b55de812043b670cbde810d7d42f45909b6d66ef
ToppCell	IPF-Lymphoid-NK\|IPF / Disease state, Lineage and Cell class	ZFPM1 TXK CCL3 VAV3 ATM	1.36e-04	189	116	5	d92e880162450f8d01e4b8784eb625275cb8e03e
ToppCell	PND01-Epithelial-Epithelial_Airway\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	C16orf96 CFAP54 DNAH12 MAPK15 AGBL2	1.36e-04	189	116	5	38cde34295566a4ecaf7d0a81c5a192cf17d0459
ToppCell	PND01-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	C16orf96 CFAP54 DNAH12 MAPK15 AGBL2	1.36e-04	189	116	5	4e83e49d1265ffe507fdb72924c77c4d1c73f0bd
ToppCell	367C-Lymphocytic-NK_cells-NK_cell_B1\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	ZNF273 ARHGEF12 RNF123 PIK3C3 TSPAN13	1.40e-04	190	116	5	2434b8ad2976eab7d9147012c28454ab29670709
ToppCell	COVID-19-kidney-NK\|kidney / Disease (COVID-19 only), tissue and cell type	LYST TXK CCL3 ATM PREX1	1.40e-04	190	116	5	e3ca3c9fb9e27670a5dd128dd6564ff98a57159e
ToppCell	(4)_Endothelial_cells-(40)_EC-arterial\|(4)_Endothelial_cells / Cell class and subclass of bone marrow stroma cells in homeostatis	HTR2B CYSLTR1 TSPAN13 TLN2 SLC66A3	1.40e-04	190	116	5	ff774faf3f12759d11e50ed7d189288bb79e22e1
ToppCell	Fetal_29-31_weeks-Immune-natural_killer_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	TXK CCL3 VAV3 ATM PREX1	1.43e-04	191	116	5	5696e2e2db7b898a1c7ab3582ae74cb712dd5bdf
ToppCell	367C-Lymphocytic-NK_cells-NK_cell_B1\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	ZNF273 ARHGEF12 RNF123 PIK3C3 TSPAN13	1.43e-04	191	116	5	39ef8e1d7cc3ebb11717e8a55501515e3b72b177
ToppCell	Children_(3_yrs)-Immune-natural_killer_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ZFPM1 TXK VAV3 ATM PREX1	1.43e-04	191	116	5	9b8b64a36e27a2523b8730c7922fd7ad865a021e
ToppCell	PND01-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	C16orf96 CFAP54 DNAH12 MAPK15 AGBL2	1.43e-04	191	116	5	96483adb97c81208aa513782550acd8a08b63866
ToppCell	IPF-Lymphoid-NK\|World / Disease state, Lineage and Cell class	ZFPM1 TXK CCL3 VAV3 ATM	1.43e-04	191	116	5	f206159b9d5e84cf14a65bfdc008895cec5a8081
ToppCell	PBMC-Severe-Myeloid-Neutrophil-immature_Neutrophil-Neu_4\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ORC6 PIWIL4 SLC28A3 OSBPL1A MED12L	1.50e-04	193	116	5	ccab6a0c76f574ef7e1d6d5f1e620376daf21bbf
ToppCell	Control-NK_CD56bright\|Control / Disease condition and Cell class	LYST TXK MMRN1 STARD9 VAV3	1.50e-04	193	116	5	8b1e7a226a6057e1097c1525984127b54e823876
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.3\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ARFGEF3 CFAP54 DNAH12 MAPK15 ROS1	1.50e-04	193	116	5	bdb7401dd9059032f930f2b575f2ef8e504b6594
ToppCell	Children_(3_yrs)-Immune-natural_killer_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	TXK CCL3 VAV3 ATM PREX1	1.50e-04	193	116	5	1cb666375bc4e1b11a146d20896c9b5ae6fd0887
ToppCell	ASK440-Epithelial-Ciliated\|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq	PLEKHS1 CFAP54 DNAH12 MAPK15 AGBL2	1.50e-04	193	116	5	a0baa8be6f590b2031fede22be588715ae458e93
ToppCell	wk_20-22-Epithelial-Proximal_epithelial-MUC16+_ciliated\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	PLEKHS1 CFAP54 DNAH12 MAPK15 AGBL2	1.54e-04	194	116	5	756082a0f5953b52229bb60d40b84701cb6cb23d
ToppCell	PBMC-Severe-Myeloid-Neutrophil-immature_Neutrophil-Neu_4\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	ORC6 PIWIL4 SLC28A3 OSBPL1A MED12L	1.54e-04	194	116	5	23318a1b55895b5166c6151f488a94a09b4627ff
ToppCell	ASK452-Endothelial-Lymphatic\|Endothelial / Donor, Lineage and Cell class of Lung cells from Dropseq	BTBD3 MMRN1 ZNF35 STARD9 KLHL18	1.58e-04	195	116	5	20f492299a684ac1b7dd1bbc36a533cd6f9a1c93
ToppCell	IPF-Multiplet-Multiplet\|IPF / Disease state, Lineage and Cell class	ARHGEF12 PLEKHS1 ARFGEF3 CFAP54 DNAH12	1.58e-04	195	116	5	fce0c29574bb7aab181b9c00feb42681e285d1f2
ToppCell	Healthy-Classical_Monocyte\|World / disease group, cell group and cell class	ZNF385A ZNF467 LYST NLRP3 CCL3	1.58e-04	195	116	5	0d96f456cc84ebb2543406fb2374c6d7cedd3c4d
ToppCell	Parenchymal-NucSeq-Stromal-Mesofibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SLC28A3 PTGER3 NLRP14 ATRNL1 NPC1L1	1.58e-04	195	116	5	a52685f76eca269a7d2de8dfc317439483e233fa
ToppCell	IPF-Multiplet\|IPF / Disease state, Lineage and Cell class	ARHGEF12 PLEKHS1 ARFGEF3 CFAP54 DNAH12	1.58e-04	195	116	5	eacc0449ae6f3ad8002268cd061467684c6fb9a7
ToppCell	Parenchymal-NucSeq-Stromal-Mesofibroblastic-Mesothelia\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SLC28A3 PTGER3 NLRP14 ATRNL1 NPC1L1	1.58e-04	195	116	5	224deeba2f60def6543a55bb4f5ee6c7fdab3f02
ToppCell	COVID-19-lung-Capillary_Aerocytes\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ARHGEF12 ACVRL1 AJAP1 STARD9 PREX1	1.62e-04	196	116	5	49cc0a2b9739abad61dff7292ea0b14d28ff35c4
ToppCell	cellseq2-Epithelial-Epithelial_Glandular-Serous\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	PLEKHS1 SLC28A3 PTGER3 ARFGEF3 TSPAN13	1.66e-04	197	116	5	d3539607d5477f5dfd85f1fa99b74677c0fa8937
ToppCell	cellseq2-Epithelial-Epithelial_Glandular-Serous-Serous\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	PLEKHS1 SLC28A3 PTGER3 ARFGEF3 TSPAN13	1.66e-04	197	116	5	40bd7c314ff5254d87737822078e7b9eaf23edf3
ToppCell	Parenchymal-10x3prime_v2-Immune_Lymphocytic-NK-ILC-T_NK-ILC\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	CYSLTR1 SCX TXK MED12L ADGRF3	1.66e-04	197	116	5	cd9172af705f9589890252ab5e8b333ed754bea4
ToppCell	Transverse-T_cell-Tcm\|T_cell / Region, Cell class and subclass	CYSLTR1 AMIGO1 TXK MED12L DIP2C	1.69e-04	198	116	5	62990b9ff7ca20895fed07461baba6c2caaa995e
ToppCell	proximal-Epithelial-Mucous-3\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	VTCN1 PLEKHS1 ATP13A5 SLC28A3 SLC44A5	1.73e-04	199	116	5	baac580484124b7c36717b607adcf2cb446e631d
ToppCell	proximal-Epithelial-Mucous\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	VTCN1 PLEKHS1 ATP13A5 SLC28A3 SLC44A5	1.73e-04	199	116	5	15ba36fa6ad73d0e959e42f18d7acbc14e310dc9
ToppCell	proximal-3-Epithelial-Mucous\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	VTCN1 PLEKHS1 ATP13A5 SLC28A3 SLC44A5	1.73e-04	199	116	5	3018378860de084662be0cc46fce421db3bb9ec9
ToppCell	Neuronal-Inhibitory-iB-iB_3(PVALB-SST)-MIR548F2--L5-6\|Neuronal / cells hierarchy compared to all cells using T-Statistic	FRMPD1 ZNF385D ANKRD34B VAV3 PLD5	1.78e-04	200	116	5	3cbb01039d1e7635ec4dcdf0223587f7ea3c7b34
ToppCell	COVID-19-COVID-19_Severe-Myeloid-immature_Neutrophil\|COVID-19_Severe / Disease, condition lineage and cell class	PIWIL4 SLC28A3 NLRC4 OSBPL1A MED12L	1.78e-04	200	116	5	cbe667eda1af222467df8bfa157aa22df488f133
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-Activated_Alv_Cap\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	ARHGEF12 ACVRL1 LUZP1 BTBD3 TSPAN13	1.78e-04	200	116	5	bcd1cc96197929d6011903803b6f4ccdcf52b4ce
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_airway_ciliated-Ciliated\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PLEKHS1 CFAP54 DNAH12 MAPK15 AGBL2	1.78e-04	200	116	5	926a7ea94b5908aebf103893ea83ce9d25285b65
ToppCell	Neuronal-Inhibitory-iB-iB_3(PVALB-SST)-MIR548F2-\|Neuronal / cells hierarchy compared to all cells using T-Statistic	FRMPD1 ZNF385D ANKRD34B VAV3 PLD5	1.78e-04	200	116	5	97a010a1b6d551239cf6ea5a43319fb413ff180e
ToppCell	Parenchymal-NucSeq-Immune_Lymphocytic-NK-ILC-T_NK-NK\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	TXK CCL3 VAV3 ATM PREX1	1.78e-04	200	116	5	7d90fcb5dfc4c9d562c93b0f9293ed12b5f4f404
ToppCell	Parenchymal-NucSeq-Immune_Lymphocytic-NK-ILC\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	TXK CCL3 VAV3 ATM PREX1	1.78e-04	200	116	5	d2422aaf807010194994db97142b9fd2e807312d
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Activated_Alv_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	ARHGEF12 ACVRL1 LUZP1 BTBD3 OSBPL1A	1.78e-04	200	116	5	79e51afb57ca38aacebd0298e5e727b55c0cfff9
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-Alv_Cap\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	ARHGEF12 ACVRL1 LUZP1 BTBD3 TSPAN13	1.78e-04	200	116	5	66f7e8ee63c828f17468e79a4b816346b33e8980
ToppCell	Neuronal-Inhibitory-iB-iB_3(PVALB-SST)-MIR548F2\|Neuronal / cells hierarchy compared to all cells using T-Statistic	FRMPD1 ZNF385D ANKRD34B VAV3 PLD5	1.78e-04	200	116	5	8ccf2dbbe34b26fbf2bbef1e64b4ae636edd6672
ToppCell	Tracheal-NucSeq-Endothelial-Endothelia_vascular-VE_alveolar_capillary_Car4_aerocyte\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	GDPD3 ZFPM1 ACVRL1 ROS1 PREX1	1.78e-04	200	116	5	fe493b0454a20498e9ada482bf55de64519f6c35
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_airway_ciliated\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PLEKHS1 CFAP54 DNAH12 MAPK15 AGBL2	1.78e-04	200	116	5	06ce6e03498ba38ef6a06eaf2731e3b2eeda59eb
ToppCell	Parenchymal-10x3prime_v2-Immune_Myeloid-Macrophage_alveolar-Macro_alv_MT\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	TRAPPC11 SLC28A3 NLRP3 CCL3 KLHL18	1.78e-04	200	116	5	f11ae9055e72c938b6c9e52701478b2eee681ac4
ToppCell	COVID-19-COVID-19_Convalescent-Myeloid\|COVID-19_Convalescent / Disease, condition lineage and cell class	ZNF385A ZNF467 LYST NLRP3 CCL3	1.78e-04	200	116	5	874d1ad41b580c885a3c8522290e92d6eb693711
ToppCell	control-HLA-DR-_S100A+_Monocyte\|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	FKBP15 ZNF385A ZNF467 LYST NLRP3	1.78e-04	200	116	5	9e3e13a68bc1110fa000ec2d80f4c654ddbce17e
ToppCell	Parenchymal-NucSeq-Immune_Lymphocytic-NK-ILC-T_NK\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	TXK CCL3 VAV3 ATM PREX1	1.78e-04	200	116	5	1d2ee63010b7b8b38bea7d3b30eebfbcdd18b967
Disease	Cryopyrin-Associated Periodic Syndromes	NLRC4 NLRP3	8.37e-05	4	111	2	C2316212
Disease	Chronic Infantile Neurological, Cutaneous, and Articular Syndrome	NLRC4 NLRP3	8.37e-05	4	111	2	C0409818
Disease	Familial Cold Autoinflammatory Syndrome 1	NLRC4 NLRP3	8.37e-05	4	111	2	C4551895
Disease	Familial cold urticaria	NLRC4 NLRP3	8.37e-05	4	111	2	C0343068
Disease	Familial cold autoinflammatory syndrome	NLRC4 NLRP3	8.37e-05	4	111	2	cv:C0343068
Disease	Muckle-Wells Syndrome	NLRC4 NLRP3	1.39e-04	5	111	2	C0268390
Disease	Hereditary Autoinflammatory Diseases	NLRC4 NLRP3	2.91e-04	7	111	2	C0751422
Disease	Autoinflammatory disorder	NLRC4 NLRP3 IFIH1	3.11e-04	35	111	3	C3860213
Disease	Drug Allergy	CYSLTR1 PTGER3 NLRP3	3.11e-04	35	111	3	C0013182
Disease	Familial pulmonary arterial hypertension	ACVRL1 EIF2AK4	3.87e-04	8	111	2	C1701939
Disease	Pulmonary Hypertension	HTR2B ACVRL1 EIF2AK4	4.63e-04	40	111	3	C0020542
Disease	Spastic Paraplegia	LYST WDR48	4.96e-04	9	111	2	C0037772
Disease	Pulmonary arterial hypertension	ACVRL1 EIF2AK4	6.19e-04	10	111	2	C2973725
Disease	myeloid white cell count	FKBP15 ARHGEF12 ACVRL1 NLRP3 IFIH1 ZNF516 POLI MED12L TLN2 VAV3 PREX1	8.23e-04	937	111	11	EFO_0007988
Disease	2-oxo-hept-3-ene-1,7-dioate hydratase activity	ACVRL1 EIF2AK4	1.24e-03	14	111	2	C1150929
Disease	Idiopathic pulmonary arterial hypertension	ACVRL1 EIF2AK4	1.63e-03	16	111	2	C3203102
Disease	primary autosomal recessive microcephaly (is_implicated_in)	PDCD6IP WDR62	1.63e-03	16	111	2	DOID:0070296 (is_implicated_in)
Disease	response to haloperidol	AJAP1 EIF2AK4	1.63e-03	16	111	2	GO_1905119
Disease	Familial primary pulmonary hypertension	ACVRL1 EIF2AK4	1.84e-03	17	111	2	C0340543
Disease	colorectal cancer	PTBP3 PIWIL4 PLEKHS1 ZNF519 PIGU ZBTB40 PREX1 KLHL18	2.05e-03	604	111	8	MONDO_0005575
Disease	neutrophil count	ARHGEF12 ACVRL1 NLRP3 IFIH1 ZC3H7A ZNF516 OSBPL1A POLI TLN2 VAV3 AGBL2 PREX1 ZMYM4	2.09e-03	1382	111	13	EFO_0004833
Disease	nasopharyngeal neoplasm	ZNF507 SLC28A3 PIGU OSBPL1A	2.58e-03	151	111	4	EFO_0004252
Disease	tobacco smoke exposure measurement	RRN3P2 AMIGO1	3.67e-03	24	111	2	EFO_0009115

Protein segments in the cluster

Peptide	Gene	Start	Entry
LYCALCKVAVNSLSQ	ZNF385A	201	Q96PM9
CSLCKVAVNSASQLE	ZNF385D	206	Q9H6B1
FITNITLVLCDSCNQ	HTR2B	341	P41595
SLVSCCLQILSCASK	ADGRF3	1046	Q8IZF5
AACLCASNILSCSKQ	AMIGO1	36	Q86WK6
IQCCSEIASLFLNDK	CFAP54	3036	Q96N23
SIFLNSCFSCIVQIS	ATP13A5	976	Q4VNC0
EAKFCNLSLSSNSLC	EIF2AK4	1241	Q9P2K8
ALITTLVLKNCCAQS	AJAP1	296	Q9UKB5
SAKNACVLLSQSCLF	BTBD3	221	Q9Y2F9
FKSRNVLVKSNLQCC	ACVRL1	331	P37023
ESQILASLQCCESSK	AGAP2	906	Q99490
TLINGLSCKNNKFIC	ADAM32	476	Q8TC27
ICATDIVSCTNKNLS	AMIGO2	46	Q86SJ2
LKNSLLADTCCRQSI	BBS12	216	Q6ZW61
NGQCSCFQSIELLKS	ARHGEF12	366	Q9NZN5
VALCVINSKSALCNA	PDS5A	1081	Q29RF7
DLLQAFSQLICTCNS	INTS7	626	Q9NVH2
SAKILCCISCNSNIQ	NUP205	916	Q92621
CSDFLIKSINLVNCL	KBTBD3	141	Q8NAB2
SDINVNNKICSLLSC	ANKRD34B	461	A5PLL1
IKSCLSRSNEQCSFI	AP4S1	36	Q9Y587
SNCLTITCLLGCFIK	PCDH19	716	Q8TAB3
IANFSSELTACCTVL	MED12L	1031	Q86YW9
QLVSCCLSANAVKIL	NLRC4	826	Q9NPP4
IQIKTQAALSNLTCC	MMRN1	971	Q13201
SNVLLDANCTVKLCD	MAPK15	141	Q8TD08
CVLLTECQFTNKSTS	FANCM	921	Q8IYD8
SCVLFNCAALASQIA	PDCD6IP	121	Q8WUM4
FSCNLATIKALVSRC	PTGER3	246	P43115
QVCIAKCNSTSSLDA	FKBP15	166	Q5T1M5
VCLICLSAFTTKANC	ZFPM1	321	Q8IX07
CRLCNIKFSSLSTFI	ZFPM1	976	Q8IX07
LAKALAVQCVVFNCS	DNAH12	1266	Q6ZR08
FSCSCLNQLLAVVSK	GDPD3	241	Q7L5L3
VSFLQKRLCLSNCLA	KLHL40	121	Q2TBA0
NQKEVLRCFTVLACS	MROH1	331	Q8NDA8
TCVALTDCLNLFTKQ	OSBPL1A	411	Q9BXW6
ILSCVAKSTCAINNT	PIGU	151	Q9H490
VVKNCANTTRSFCDL	IFNAR2	81	P48551
NTQACCSAKQLVSLE	NPC1L1	86	Q9UHC9
KNLLFSVCGLTICAA	FAM189B	171	P81408
LKFLCLCVTTAQTNT	ATM	901	Q13315
QLCSFILKTSQCTLK	APOB	86	P04114
SFLQLQSIKDACCTF	KLHL18	116	O94889
QNATSLKCKSCNLLT	C16orf96	981	A6NNT2
AACDILSQLVNCSLK	FBXL3	126	Q9UKT7
RQCTALTAAVFCLTQ	FRMPD1	1556	Q5SYB0
LACCALQDAFSATLK	ARFGEF3	1606	Q5TH69
SLITFLCKNCSVLAC	IFIH1	901	Q9BYX4
ATSAFCRSIKLQCEL	DIP2C	1156	Q9Y2E4
KSCALSNLACIRDIF	F11	191	P03951
QSQFCKLQTLCRSLA	AGBL2	416	Q5U5Z8
CNKLTSCKSCSLNLN	ATRNL1	716	Q5VV63
LLCTMALCNQFSASL	CCL3	11	P10147
NTINLFLCVAFLCVS	LYST	896	Q99698
AFSRSKNDCTQLCLS	LUZP1	126	Q86V48
KRTQNTLSKFLQCCL	SLC44A5	541	Q8NCS7
IIIFTNTCKTCQILC	DDX49	251	Q9Y6V7
LSVCFCNLKALNTAK	POLI	431	Q9UNA4
SCRNVIDVTSFAKNC	OTOGL	1146	Q3ZCN5
LSVARTISFNCCALQ	OR10R2	106	Q8NGX6
LILCSQRKALSTCAF	OR4C5	241	Q8NGB2
CCFDISLVLSSNQKL	NLRP3	786	Q96P20
FELCLAKCRTSSQSV	SPRING1	166	Q9H741
ISSLKAICTEIANCS	PLD5	396	Q8N7P1
SSSLCQLDISSNCIK	LRRC41	731	Q15345
CTFLISRACKNSTLA	PIK3C3	476	Q8NEB9
LSCFTQTCEKQLIGL	PIWIL4	286	Q7Z3Z4
IFCQALVAAVCTFSK	PREX1	1326	Q8TCU6
SCLKSFECLLGLNSN	ORC6	81	Q9Y5N6
NTTKVIACCQSLLSS	SLC28A3	636	Q9HAS3
IACCQSLLSSTVAKG	SLC28A3	641	Q9HAS3
SLVYLVCNTTLCALK	STARD9	4586	Q9P2P6
LAICSQCSDISTKQA	RO60	96	P10155
LSCKVCLQTFESTQA	PLAGL2	156	Q9UPG8
TVSSFCLQHCKALIQ	CLBA1	256	Q96F83
SVVITLSLAASNCCF	CYSLTR1	276	Q9Y271
NSESSVRKACVFCLV	CLASP2	1231	O75122
STNLCLSFLFCKIMT	PLEKHS1	441	Q5SXH7
IVTQFTTQFLKLCCL	PRAMEF6	256	Q5VXH4
ICLLQTFSLCLTAVF	TSPAN33	91	Q86UF1
VCAKCGNLFTNLDSL	ZNF516	336	Q92618
SECGKAFSQLSCLIV	ZNF35	421	P13682
LNQCLTTTQSKIFQC	ZNF273	166	Q14593
CLSTTQSKIFQCNTC	ZNF595	136	Q8IYB9
LSQFDTVIKCTRNVC	ZNF542P	86	Q5EBM4
IVLCCNGKTLISASS	WDR48	81	Q8TAF3
SQRCNKKCIIVFSQS	ZNF519	236	Q8TB69
LCNACELSGKSLFVL	TRAPPC11	161	Q7Z392
FIVQFSVSCACLALN	TSPAN13	86	O95857
CFLLKFSLTISSCLI	TMEM94	1171	Q12767
RQLKVCATCFDLSVS	RNF123	1066	Q5XPI4
IVTQFTTQFLKLCCL	PRAMEF5	256	Q5TYX0
VISCSCLAINRSKQT	TSPAN31	91	Q12999
QCTVLNSCLKSCVTN	ROS1	26	P08922
SQSLANNSKICTIEC	RRN3P2	186	A6NIE6
CTFISAASKFAQLQC	SLC66A3	121	Q8N755
NACCTLRIDFSKLTS	PTBP3	246	O95758
INLKVSLSSCLCVSQ	WDR62	291	O43379
DCNIVLSLNASNCKA	ZC3H7A	111	Q8IWR0
QCSLCKFLSSSFSVL	ZNF507	126	Q8TCN5
LAARNCLVSSTCIVK	TXK	391	P42681
TNTQCKVCCALLISE	ZNF346	71	Q9UL40
QCALSTSQLVACAKV	TLN2	711	Q9Y4G6
ALCNACRIASSKTAN	TLN2	1506	Q9Y4G6
QCIESGKSFNCSSLL	ZNF28	216	P17035
SLDVCLNKKACNTQF	SPZ1	396	Q9BXG8
KQICTFCLSNQRKLS	SCX	176	Q7RTU7
VQRISCFQSTVKCLT	WDR41	126	Q9HAD4
QRKGSTQLFCSTLCL	ZMYM4	356	Q5VZL5
ACAVCARSFSSKTNL	ZNF467	516	Q7Z7K2
AICSSLQNLEKTIFC	ZHX1-C8orf76	106	Q96EF9
AVSCKNLLTSLVNCS	ZBTB40	106	Q9NUA8
QALAVCANICLATKD	TMEM260	301	Q9NX78
LQLLNSKASLCVSSF	VTCN1	251	Q7Z7D3
QCISKIASNACFVVV	TMEM272	11	A0A1B0GTI8
CLKNIRTFLTACCET	VAV3	71	Q9UKW4
LQSCISLRVCIFSNN	LRRIQ3	46	A6PVS8
TVFCCLNISNALIRS	NLRP14	771	Q86W24