Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	neuron projection development	DLG5 RELN RIPOR2 NYAP2 HECW1 ADAMTS1 NEUROD4 USP9X LAMA5 GPRIN3 CHAT ALS2 ADAM10 NEDD4 PLEKHG4B ZNF335 PLXNA4 GOLGA8B MINAR1 ROBO3 NDRG4 GOLGA2 PLXNA2 USP33	1.09e-06	1285	128	24	GO:0031175
GeneOntologyBiologicalProcess	neuron development	DLG5 RELN RIPOR2 NYAP2 HECW1 ADAMTS1 NEUROD4 USP9X LAMA5 GPRIN3 CHAT ALS2 ADAM10 NEDD4 PLEKHG4B ZNF335 PLXNA4 GOLGA8B MINAR1 ROBO3 NDRG4 GOLGA2 PLXNA2 USP33	1.01e-05	1463	128	24	GO:0048666
GeneOntologyBiologicalProcess	SA node cell to atrial cardiac muscle cell signaling	ANK2 RYR2 CACNA1G	2.71e-05	10	128	3	GO:0086018
GeneOntologyBiologicalProcess	SA node cell action potential	ANK2 RYR2 CACNA1G	2.71e-05	10	128	3	GO:0086015
GeneOntologyBiologicalProcess	SA node cell to atrial cardiac muscle cell communication	ANK2 RYR2 CACNA1G	3.71e-05	11	128	3	GO:0086070
GeneOntologyBiologicalProcess	neuron projection morphogenesis	RELN NYAP2 HECW1 USP9X LAMA5 ALS2 ADAM10 NEDD4 PLEKHG4B ZNF335 PLXNA4 GOLGA8B ROBO3 GOLGA2 PLXNA2 USP33	3.77e-05	802	128	16	GO:0048812
GeneOntologyBiologicalProcess	plasma membrane bounded cell projection morphogenesis	RELN NYAP2 HECW1 USP9X LAMA5 ALS2 ADAM10 NEDD4 PLEKHG4B ZNF335 PLXNA4 GOLGA8B ROBO3 GOLGA2 PLXNA2 USP33	4.84e-05	819	128	16	GO:0120039
GeneOntologyBiologicalProcess	AV node cell to bundle of His cell signaling	ANK2 RYR2 CACNA1G	4.93e-05	12	128	3	GO:0086027
GeneOntologyBiologicalProcess	AV node cell action potential	ANK2 RYR2 CACNA1G	4.93e-05	12	128	3	GO:0086016
GeneOntologyBiologicalProcess	cell projection morphogenesis	RELN NYAP2 HECW1 USP9X LAMA5 ALS2 ADAM10 NEDD4 PLEKHG4B ZNF335 PLXNA4 GOLGA8B ROBO3 GOLGA2 PLXNA2 USP33	5.35e-05	826	128	16	GO:0048858
GeneOntologyBiologicalProcess	cell morphogenesis involved in neuron differentiation	RELN RIPOR2 HECW1 USP9X LAMA5 ALS2 ADAM10 NEDD4 PLEKHG4B PLXNA4 GOLGA8B ROBO3 GOLGA2 PLXNA2 USP33	6.32e-05	748	128	15	GO:0048667
GeneOntologyBiologicalProcess	AV node cell to bundle of His cell communication	ANK2 RYR2 CACNA1G	1.01e-04	15	128	3	GO:0086067
GeneOntologyBiologicalProcess	regulation of SA node cell action potential	ANK2 RYR2	1.14e-04	3	128	2	GO:0098907
GeneOntologyBiologicalProcess	regulation of atrial cardiac muscle cell action potential	ANK2 RYR2	2.27e-04	4	128	2	GO:0098910
Domain	HECT	HECW1 HUWE1 NEDD4 HERC2	3.07e-05	27	126	4	PF00632
Domain	HECTc	HECW1 HUWE1 NEDD4 HERC2	3.07e-05	27	126	4	SM00119
Domain	HECT_dom	HECW1 HUWE1 NEDD4 HERC2	3.07e-05	27	126	4	IPR000569
Domain	HECT	HECW1 HUWE1 NEDD4 HERC2	3.07e-05	27	126	4	PS50237
Domain	ZINC_FINGER_C2H2_2	ZFAT ZNF473 ZNF521 KLF15 ZNF235 ZNF831 ZIC4 ZNF106 ZNF469 ZBTB39 ZNF644 ZNF335 ZNF483 ZNF81 ZFP69B ZNF625	6.66e-05	775	126	16	PS50157
Domain	zf-C2H2	ZFAT ZNF473 ZNF521 KLF15 ZNF235 ZIC4 ZNF106 ZNF469 ZBTB39 ZNF644 ZNF335 ZNF483 ZNF81 ZFP69B ZNF625	6.76e-05	693	126	15	PF00096
Domain	ZINC_FINGER_C2H2_1	ZFAT ZNF473 ZNF521 KLF15 ZNF235 ZNF831 ZIC4 ZNF106 ZNF469 ZBTB39 ZNF644 ZNF335 ZNF483 ZNF81 ZFP69B ZNF625	6.87e-05	777	126	16	PS00028
Domain	Znf_C2H2/integrase_DNA-bd	ZFAT ZNF473 ZNF521 KLF15 ZNF235 ZNF831 ZIC4 ZNF469 ZBTB39 ZNF644 ZNF335 ZNF483 ZNF81 ZFP69B ZNF625	6.87e-05	694	126	15	IPR013087
Domain	Znf_C2H2-like	ZFAT ZNF473 ZNF521 KLF15 ZNF235 ZNF831 ZIC4 ZNF106 ZNF469 ZBTB39 ZNF644 ZNF335 ZNF483 ZNF81 ZFP69B ZNF625	9.11e-05	796	126	16	IPR015880
Domain	Znf_C2H2	ZFAT ZNF473 ZNF521 KLF15 ZNF235 ZNF831 ZIC4 ZNF106 ZNF469 ZBTB39 ZNF644 ZNF335 ZNF483 ZNF81 ZFP69B ZNF625	1.04e-04	805	126	16	IPR007087
Domain	ZnF_C2H2	ZFAT ZNF473 ZNF521 KLF15 ZNF235 ZNF831 ZIC4 ZNF106 ZNF469 ZBTB39 ZNF644 ZNF335 ZNF483 ZNF81 ZFP69B ZNF625	1.08e-04	808	126	16	SM00355
Domain	REELIN	RELN FRRS1	1.35e-04	3	126	2	PS51019
Domain	Reeler_dom	RELN FRRS1	1.35e-04	3	126	2	IPR002861
Domain	Reeler	RELN FRRS1	1.35e-04	3	126	2	PF02014
Domain	-	ZFAT ZNF473 ZNF521 KLF15 ZNF235 ZNF831 ZIC4 ZBTB39 ZNF644 ZNF335 ZNF483 ZNF81 ZFP69B ZNF625	1.98e-04	679	126	14	3.30.160.60
Domain	WW	HECW1 WAC NEDD4 SETD2	2.81e-04	47	126	4	PF00397
Domain	WW	HECW1 WAC NEDD4 SETD2	3.05e-04	48	126	4	SM00456
Domain	WW_DOMAIN_1	HECW1 WAC NEDD4 SETD2	3.86e-04	51	126	4	PS01159
Domain	WW_DOMAIN_2	HECW1 WAC NEDD4 SETD2	3.86e-04	51	126	4	PS50020
Domain	WW_dom	HECW1 WAC NEDD4 SETD2	4.16e-04	52	126	4	IPR001202
Domain	Helicase/UvrB_N	RTEL1 FANCM	1.23e-03	8	126	2	IPR006935
Domain	ResIII	RTEL1 FANCM	1.23e-03	8	126	2	PF04851
Domain	Plexin_repeat	ATRNL1 PLXNA4 PLXNA2	1.29e-03	32	126	3	IPR002165
Domain	PSI	ATRNL1 PLXNA4 PLXNA2	1.29e-03	32	126	3	PF01437
Pubmed	Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	RIPOR2 HECW1 ZFYVE16 HUWE1 ZBTB39 PER2 HERC2 KAT6B	6.21e-09	104	131	8	9205841
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	ZNF473 HECW1 RTEL1 DIS3L EXPH5 GPRIN3 FANCM WAC SETD2 ZBTB39 ATRNL1 MINAR1 UNC80	5.07e-08	493	131	13	15368895
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	HECW1 RTEL1 KIAA0232 ALS2 CACNA1G MINAR1 KAT6B NDRG4 UNC80	2.02e-07	225	131	9	12168954
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	RIPOR2 ZFYVE16 KIAA0232 ALS2 NEDD4 PER2 ZNF644 NISCH MAPKBP1 PLXNA2 USP33	4.45e-07	407	131	11	12693553
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	NCOA2 NYAP2 ANK2 HECW1 NACC1 USP9X RIPK2 HUWE1 EDC4 NEDD4 NISCH GOLGA8B HERC2 GOLGA2 TP53BP1 LRRFIP1	7.48e-07	963	131	16	28671696
Pubmed	Chat, a Cas/HEF1-associated adaptor protein that integrates multiple signaling pathways.	NPR3 CHAT NEDD9	1.04e-06	6	131	3	10692442
Pubmed	Construction of a multi-functional cDNA library specific for mouse pancreatic islets and its application to microarray.	NCOA2 ANK2 ADAMTS1 ZNF235 WAC NISCH SHPRH HERC2 KAT6B UTY	1.55e-06	371	131	10	15747579
Pubmed	Functional proteomics mapping of a human signaling pathway.	STARD13 ZFYVE16 EXPH5 INPP4A LAMA5 HUWE1 RYR2 NEDD4 HIPK3 NEDD9 ZNF106 HERC2	2.63e-06	591	131	12	15231748
Pubmed	System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes.	HECW1 HUWE1 NEDD4 HERC2	2.69e-06	26	131	4	26949039
Pubmed	Semaphorin 6A in Retinal Ganglion Cells Regulates Functional Specialization of the Inner Retina.	CHAT PLXNA4 PLXNA2	4.31e-06	9	131	3	38014224
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	DLG5 EXPH5 KIAA0232 RIPK2 ALS2 ITPRID2 EDC4 NEDD4 ZNF106 KCNQ5 CCSER2 NHS NR3C2 GEN1	4.93e-06	861	131	14	36931259
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	NCOA2 RELN ANK2 ZNF473 ADAMTS1 DIS3L USP9X ZNF521 HUWE1 REV3L WAC ATRNL1 NISCH HERC2 GEN1 USP33 LRRFIP1	7.08e-06	1285	131	17	35914814
Pubmed	Transcriptome analysis of mouse stem cells and early embryos.	LAMA5 ALS2 WAC ZNF106 FRRS1 ZNF335 NHS CACNA1G USP33	1.03e-05	363	131	9	14691545
Pubmed	On and off retinal circuit assembly by divergent molecular mechanisms.	CHAT PLXNA4 PLXNA2	1.12e-05	12	131	3	24179230
Pubmed	Identification of the binding site for the Lutheran blood group glycoprotein on laminin alpha 5 through expression of chimeric laminin chains in vivo.	LAMA5 BCAM	1.41e-05	2	131	2	12244066
Pubmed	Laminin alpha 5 mediates ectopic adhesion of hepatocellular carcinoma through integrins and/or Lutheran/basal cell adhesion molecule.	LAMA5 BCAM	1.41e-05	2	131	2	18635166
Pubmed	An antibody to the lutheran glycoprotein (Lu) recognizing the LU4 blood type variant inhibits cell adhesion to laminin α5.	LAMA5 BCAM	1.41e-05	2	131	2	21858073
Pubmed	BCAM and LAMA5 Mediate the Recognition between Tumor Cells and the Endothelium in the Metastatic Spreading of KRAS-Mutant Colorectal Cancer.	LAMA5 BCAM	1.41e-05	2	131	2	27143691
Pubmed	Increased Expression of Y-Encoded Demethylases During Differentiation of Human Male Neural Stem Cells.	KDM5D UTY	1.41e-05	2	131	2	33040644
Pubmed	The ubiquitin ligase TRIM25 targets ERG for degradation in prostate cancer.	USP9X HUWE1 HERC2	1.84e-05	14	131	3	27626314
Pubmed	A midline switch of receptor processing regulates commissural axon guidance in vertebrates.	PLXNA4 ROBO3 PLXNA2	1.84e-05	14	131	3	20159958
Pubmed	Plexin-A3 mediates semaphorin signaling and regulates the development of hippocampal axonal projections.	RELN PLXNA4 PLXNA2	3.42e-05	17	131	3	11683995
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	FILIP1 NACC1 ITPRID2 HUWE1 ZNF106 SETD2 DBF4 ZNF644 ZNF335 KAT6B TP53BP1 LRRFIP1	3.84e-05	774	131	12	15302935
Pubmed	Sex differences in sex chromosome gene expression in mouse brain.	USP9X KDM5D UTY	4.09e-05	18	131	3	12023983
Pubmed	Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	ALS2 HUWE1 FANCM ZFYVE28 PLXNA4	4.16e-05	101	131	5	10997877
Pubmed	Structural Basis for Plexin Activation and Regulation.	PLXNA4 PLXNA2	4.21e-05	3	131	2	27397516
Pubmed	Interactions between plexin-A2, plexin-A4, and semaphorin 6A control lamina-restricted projection of hippocampal mossy fibers.	PLXNA4 PLXNA2	4.21e-05	3	131	2	17296555
Pubmed	Transcription factor KLF15 inhibits the proliferation and migration of gastric cancer cells via regulating the TFAP2A-AS1/NISCH axis.	KLF15 NISCH	4.21e-05	3	131	2	34727954
Pubmed	Population genetic implications from sequence variation in four Y chromosome genes.	KDM5D UTY	4.21e-05	3	131	2	10861003
Pubmed	The lutheran/basal cell adhesion molecule promotes tumor cell migration by modulating integrin-mediated cell attachment to laminin-511 protein.	LAMA5 BCAM	4.21e-05	3	131	2	24036115
Pubmed	Glycophorin-C sialylation regulates Lu/BCAM adhesive capacity during erythrocyte aging.	LAMA5 BCAM	4.21e-05	3	131	2	29344581
Pubmed	Activation of ULK Kinase and Autophagy by GABARAP Trafficking from the Centrosome Is Regulated by WAC and GM130.	WAC GOLGA2	4.21e-05	3	131	2	26687599
Pubmed	Role of transmembrane semaphorin Sema6A in oligodendrocyte differentiation and myelination.	PLXNA4 PLXNA2	4.21e-05	3	131	2	22777942
Pubmed	Ectodomain shedding of the cell adhesion molecule Nectin-4 in ovarian cancer is mediated by ADAM10 and ADAM17.	ADAM10 NECTIN4	4.21e-05	3	131	2	28232483
Pubmed	Postmortem genetic analysis of sudden unexplained death syndrome under 50 years of age: A next-generation sequencing study.	ANK2 RYR2	4.21e-05	3	131	2	27005929
Pubmed	The Circadian Clock Regulates Adipogenesis by a Per3 Crosstalk Pathway to Klf15.	KLF15 PER2	4.21e-05	3	131	2	29186676
Pubmed	NudC-like protein 2 restrains centriole amplification by stabilizing HERC2.	HERC2 USP33	4.21e-05	3	131	2	31427565
Pubmed	Degradation of the deubiquitinating enzyme USP33 is mediated by p97 and the ubiquitin ligase HERC2.	HERC2 USP33	4.21e-05	3	131	2	24855649
Pubmed	Repulsive and attractive semaphorins cooperate to direct the navigation of cardiac neural crest cells.	PLXNA4 PLXNA2	4.21e-05	3	131	2	18625214
Pubmed	Differential expression of ADAM (a disintegrin and metalloproteinase) genes between human first trimester villous and extravillous trophoblast cells.	ADAMTS1 ADAM10	4.21e-05	3	131	2	24998958
Pubmed	Lutheran blood group glycoprotein and its newly characterized mouse homologue specifically bind alpha5 chain-containing human laminin with high affinity.	LAMA5 BCAM	4.21e-05	3	131	2	11133776
Pubmed	Localization of Lutheran, a novel laminin receptor, in normal, knockout, and transgenic mice suggests an interaction with laminin alpha5 in vivo.	LAMA5 BCAM	4.21e-05	3	131	2	11507772
Pubmed	Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.	RELN LAMA5 ADAM10 HMCN1 LOXL2 PLXNA2	5.53e-05	175	131	6	28071719
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	NCOA2 ZNF473 KLF15 BCL3 KDM5D ZNF235 DBF4 ZNF644 KAT6B UTY PLXNA2 PHTF1	5.80e-05	808	131	12	20412781
Pubmed	Analysis of the DNA sequence and duplication history of human chromosome 15.	GOLGA6L6 NEDD4 GOLGA6L22 GOLGA8B	6.07e-05	56	131	4	16572171
Pubmed	New nomenclature for chromatin-modifying enzymes.	NCOA2 KDM5D SETD2 KAT6B	6.51e-05	57	131	4	18022353
Pubmed	A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.	NCOA2 NEUROD4 ZNF521 ZNF235 ZIC4 HOXB5 PER2 NR3C2 KAT6B NDRG4 PLXNA2	8.12e-05	709	131	11	22988430
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	NCOA2 DLG5 USP9X ITPRID2 HUWE1 SETD2 APEX2 ZNF644 GOLGA2 TP53BP1	8.19e-05	588	131	10	38580884
Pubmed	GKAP-DLC2 interaction organizes the postsynaptic scaffold complex to enhance synaptic NMDA receptor activity.	STARD13 RYR2	8.41e-05	4	131	2	22328512
Pubmed	Transposition of RhoA to the murine Y chromosome.	KDM5D UTY	8.41e-05	4	131	2	9598304
Pubmed	Chromosome assignment of four plexin A genes (Plxna1, Plxna2, Plxna3, Plxna4) in mouse, rat, Syrian hamster and Chinese hamster.	PLXNA4 PLXNA2	8.41e-05	4	131	2	11306810
Pubmed	PlexinA polymorphisms mediate the developmental trajectory of human corpus callosum microstructure.	PLXNA4 PLXNA2	8.41e-05	4	131	2	25518740
Pubmed	Deubiquitinase USP9X stabilizes MCL1 and promotes tumour cell survival.	USP9X HUWE1	8.41e-05	4	131	2	20023629
Pubmed	Evidence for a cell-specific action of Reelin in the spinal cord.	RELN CHAT	8.41e-05	4	131	2	11900467
Pubmed	X- and Y-Linked Chromatin-Modifying Genes as Regulators of Sex-Specific Cancer Incidence and Prognosis.	KDM5D UTY	8.41e-05	4	131	2	32732223
Pubmed	Noxa controls Mule-dependent Mcl-1 ubiquitination through the regulation of the Mcl-1/USP9X interaction.	USP9X HUWE1	8.41e-05	4	131	2	21907705
Pubmed	The NALCN channel complex is voltage sensitive and directly modulated by extracellular calcium.	NALF1 UNC80	8.41e-05	4	131	2	32494638
Pubmed	Reelin and stk25 have opposing roles in neuronal polarization and dendritic Golgi deployment.	RELN GOLGA8B GOLGA2	8.75e-05	23	131	3	21111240
Pubmed	Ectopic clustering of Cajal-Retzius and subplate cells is an initial pathological feature in Pomgnt2-knockout mice, a model of dystroglycanopathy.	RELN GOLGA8B GOLGA2	9.98e-05	24	131	3	26060116
Pubmed	Fezl regulates the differentiation and axon targeting of layer 5 subcortical projection neurons in cerebral cortex.	RELN NPR3 PLXNA4 ROBO3 PLXNA2	1.19e-04	126	131	5	16284245
Pubmed	CDK5RAP2 expression during murine and human brain development correlates with pathology in primary autosomal recessive microcephaly.	RELN GOLGA8B GOLGA2	1.27e-04	26	131	3	22806269
Pubmed	Guidance-cue control of horizontal cell morphology, lamination, and synapse formation in the mammalian outer retina.	PLXNA4 PLXNA2	1.40e-04	5	131	2	22593055
Pubmed	The aminopeptidase ERAAP shapes the peptide repertoire displayed by major histocompatibility complex class I molecules.	KDM5D UTY	1.40e-04	5	131	2	16299505
Pubmed	Activity-Based Probes for HECT E3 Ubiquitin Ligases.	HUWE1 NEDD4	1.40e-04	5	131	2	28425671
Pubmed	Laminins promote postsynaptic maturation by an autocrine mechanism at the neuromuscular junction.	LAMA5 BCAM	1.40e-04	5	131	2	18794334
Pubmed	Klf15 orchestrates circadian nitrogen homeostasis.	KLF15 PER2	1.40e-04	5	131	2	22405069
Pubmed	A Nedd4 E3 Ubiquitin Ligase Pathway Inhibits Robo1 Repulsion and Promotes Commissural Axon Guidance across the Midline.	NEDD4 ROBO3	1.40e-04	5	131	2	36002265
Pubmed	T-type calcium channels functionally interact with spectrin (α/β) and ankyrin B.	ANK2 CACNA1G	1.40e-04	5	131	2	29720258
Pubmed	Local anesthetics impair the growth and self-renewal of glioblastoma stem cells by inhibiting ZDHHC15-mediated GP130 palmitoylation.	RTEL1 ATRNL1 UNC80 TP53BP1	1.54e-04	71	131	4	33541421
Pubmed	Expression of Robo/Slit and Semaphorin/Plexin/Neuropilin family members in the developing hypothalamic paraventricular and supraoptic nuclei.	PLXNA4 ROBO3 PLXNA2	1.60e-04	28	131	3	18617019
Pubmed	The Y172 Monoclonal Antibody Against p-c-Jun (Ser63) Is a Marker of the Postsynaptic Compartment of C-Type Cholinergic Afferent Synapses on Motoneurons.	CHAT GOLGA8B GOLGA2	1.60e-04	28	131	3	32038174
Pubmed	The DNA sequence of the human X chromosome.	RAB9B USP9X HUWE1 PPEF1 AKAP4 APEX2 MAP7D2 NHS	1.62e-04	407	131	8	15772651
Pubmed	Multimodal Hox5 activity generates motor neuron diversity.	KLF15 CHAT HOXB5	1.78e-04	29	131	3	39289460
Pubmed	Characterization of cDNA clones selected by the GeneMark analysis from size-fractionated cDNA libraries from human brain.	ZNF473 CCSER2 CACNA1G NDRG4	2.00e-04	76	131	4	10574461
Pubmed	Semaphorin-Plexin signaling influences early ventral telencephalic development and thalamocortical axon guidance.	PLXNA4 PLXNA2	2.09e-04	6	131	2	28438183
Pubmed	USP9X destabilizes pVHL and promotes cell proliferation.	USP9X HUWE1	2.09e-04	6	131	2	27517496
Pubmed	The HERC2 ubiquitin ligase is essential for embryonic development and regulates motor coordination.	HERC2 USP33	2.09e-04	6	131	2	27528230
Pubmed	Laminin-10 and Lutheran blood group glycoproteins in adhesion of human endothelial cells.	LAMA5 BCAM	2.09e-04	6	131	2	16236823
Pubmed	Roles of semaphorin-6B and plexin-A2 in lamina-restricted projection of hippocampal mossy fibers.	PLXNA4 PLXNA2	2.09e-04	6	131	2	20484647
Pubmed	β-Sheet Augmentation Is a Conserved Mechanism of Priming HECT E3 Ligases for Ubiquitin Ligation.	HUWE1 NEDD4	2.09e-04	6	131	2	29964046
Pubmed	The role of Robo3 in the development of cortical interneurons.	RELN ROBO3	2.09e-04	6	131	2	19366869
Pubmed	Failure of epithelial tube maintenance causes hydrocephalus and renal cysts in Dlg5-/- mice.	DLG5 GOLGA8B GOLGA2	2.17e-04	31	131	3	17765678
Pubmed	Amyloid Precursor Protein (APP) May Act as a Substrate and a Recognition Unit for CRL4CRBN and Stub1 E3 Ligases Facilitating Ubiquitination of Proteins Involved in Presynaptic Functions and Neurodegeneration.	HECW1 USP9X HUWE1 NEDD4	2.32e-04	79	131	4	27325702
Pubmed	USP7 represses lineage differentiation genes in mouse embryonic stem cells by both catalytic and noncatalytic activities.	KIAA0408 ANKRD31 ZNF521 ZNF235 NALF1 APEX2 LOXL2 PLXNA4 MAP7D2 UTY	2.47e-04	674	131	10	37196079
Pubmed	Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.	NCOA2 ZFAT ELP5 ICA1 KCNQ5 USP33	2.64e-04	233	131	6	37704626
Pubmed	Protein interactome reveals converging molecular pathways among autism disorders.	HECW1 KIAA0232 ICA1 LAMA5 ITPRID2 EDC4 SETD2 MAPKBP1 GOLGA2	2.84e-04	560	131	9	21653829
Pubmed	Cullin 1 (CUL1) Promotes Primary Ciliogenesis through the Induction of Ubiquitin-Proteasome-Dependent Dvl2 Degradation.	ANKRD31 RTEL1 REV3L HMCN1 APEX2	2.85e-04	152	131	5	34299191
Pubmed	Pioneering function of Isl1 in the epigenetic control of cardiomyocyte cell fate.	RYR2 KCNQ5 PLXNA2	2.87e-04	34	131	3	31024170
Pubmed	Semaphorin-6A controls guidance of corticospinal tract axons at multiple choice points.	PLXNA4 PLXNA2	2.92e-04	7	131	2	19063725
Pubmed	Increased proximal bifurcation of CA1 pyramidal apical dendrites in sema3A mutant mice.	PLXNA4 PLXNA2	2.92e-04	7	131	2	19655386
Pubmed	Mechanisms of MCL-1 Protein Stability Induced by MCL-1 Antagonists in B-Cell Malignancies.	USP9X HUWE1	2.92e-04	7	131	2	36346691
Pubmed	Pallial origin of basal forebrain cholinergic neurons in the nucleus basalis of Meynert and horizontal limb of the diagonal band nucleus.	RELN CHAT	2.92e-04	7	131	2	21865321
Pubmed	MARCH2 promotes endocytosis and lysosomal sorting of carvedilol-bound β(2)-adrenergic receptors.	NEDD4 USP33	2.92e-04	7	131	2	23166351
Pubmed	The mouse Y chromosome interval necessary for spermatogonial proliferation is gene dense with syntenic homology to the human AZFa region.	KDM5D UTY	2.92e-04	7	131	2	9736773
Pubmed	Abundance of ADAM-8, -9, -10, -12, -15 and -17 and ADAMTS-1 in mouse uterus during the oestrous cycle.	ADAMTS1 ADAM10	2.92e-04	7	131	2	15907280
Pubmed	The ancestral gene for transcribed, low-copy repeats in the Prader-Willi/Angelman region encodes a large protein implicated in protein trafficking, which is deficient in mice with neuromuscular and spermiogenic abnormalities.	HERC2P3 HERC2	2.92e-04	7	131	2	9949213
Pubmed	Novel effects of chromosome Y on cardiac regulation, chromatin remodeling, and neonatal programming in male mice.	KDM5D UTY	2.92e-04	7	131	2	24105479
Pubmed	E-cadherin interactome complexity and robustness resolved by quantitative proteomics.	DLG5 ZFYVE16 ITPRID2 CCSER2 NECTIN4 GOLGA8B NHS GOLGA2 LRRFIP1	3.03e-04	565	131	9	25468996
Pubmed	Genetic Screens Reveal FEN1 and APEX2 as BRCA2 Synthetic Lethal Targets.	RTEL1 HUWE1 FANCM APEX2 DBF4	3.31e-04	157	131	5	30686591
Pubmed	Heart neurons use clock genes to control myocyte proliferation.	CHAT RYR2 PER2	3.69e-04	37	131	3	34851661
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZFAT ZNF473 ZNF521 KLF15 ZNF235 ZIC4 ZNF106 ZNF469 ZBTB39 ZNF335 ZNF483 ZNF81 ZFP69B ZNF625	4.46e-06	718	83	14	28
GeneFamily	Plexins	PLXNA4 PLXNA2	7.34e-04	9	83	2	683
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HGABA	RAB9B RELN RIPOR2 ANK2 INPP4A LAMA5 GPRIN3 REV3L PRRT2 RYR2 NALF1 PLXNA4 SNTG1 GOLGA8B MAP7D2 CACNA1G NDRG4	2.81e-05	1106	128	17	M39071
Coexpression	GRYDER_PAX3FOXO1_ENHANCERS_IN_TADS	STARD13 C2orf69 DLG5 ANK2 ZFYVE16 ADAMTS1 DIS3L ADAM10 TRIM45 LOXL2 ZNF644 ZNF483 HERC2 TM2D1 PLXNA2 LRRFIP1	3.40e-05	1009	128	16	M157
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HNBML1	RAB9B RIPOR2 ANK2 ZNF521 GPRIN3 PRRT2 NALF1 MAP7D2 NDRG4	3.49e-05	328	128	9	M39064
Coexpression	GAUSSMANN_MLL_AF4_FUSION_TARGETS_D_UP	RAB9B NPR3 HECW1 LOXL2	3.52e-05	38	128	4	M1801
Coexpression	GAUSSMANN_MLL_AF4_FUSION_TARGETS_D_UP	RAB9B NPR3 HECW1 LOXL2	3.52e-05	38	128	4	MM481
Coexpression	DESCARTES_FETAL_THYMUS_VASCULAR_ENDOTHELIAL_CELLS	RELN ZNF521 NALF1 HMCN1 NR3C2 BCAM	4.58e-05	131	128	6	M40316
Coexpression	SCHWAB_TARGETS_OF_BMYB_POLYMORPHIC_VARIANTS_DN	BCL3 HOXB5 NR3C2	6.08e-05	16	128	3	M10651
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FILIP1 RELN USP9X INSRR HUWE1 KDM5D REV3L NISCH UTY UNC80	3.40e-10	195	131	10	3e519cffa6144a62b06124642a14c9ff39b76554
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FILIP1 RELN USP9X INSRR HUWE1 KDM5D REV3L NISCH UTY UNC80	3.40e-10	195	131	10	7796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	HECW1 ICA1 RYR2 NALF1 KCNQ5 ATRNL1 SNTG1 GOLGA8B NDRG4 UNC80	3.94e-10	198	131	10	8ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	HECW1 ICA1 RYR2 NALF1 KCNQ5 ATRNL1 SNTG1 GOLGA8B UNC80	7.03e-09	196	131	9	676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCell	Somatosensory_Cortex_(S1)-Neuronal\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	HECW1 ICA1 RYR2 NALF1 KCNQ5 ATRNL1 SNTG1 GOLGA8B UNC80	7.68e-09	198	131	9	c01091ef18e096d792ea2a7a715764a5b215355f
ToppCell	primary_auditory_cortex_(A1C)-Neuronal\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	HECW1 ICA1 RYR2 NALF1 KCNQ5 ATRNL1 SNTG1 GOLGA8B UNC80	7.68e-09	198	131	9	6d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	HECW1 ICA1 RYR2 NALF1 KCNQ5 ATRNL1 SNTG1 GOLGA8B UNC80	7.68e-09	198	131	9	4ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIAA0408 RELN ABCA4 HECW1 RYR2 HMCN1 UNC13C UNC80	7.57e-08	184	131	8	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIAA0408 RELN ABCA4 HECW1 RYR2 HMCN1 UNC13C UNC80	7.57e-08	184	131	8	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIAA0408 RELN ABCA4 HECW1 RYR2 HMCN1 UNC13C UNC80	7.57e-08	184	131	8	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ICA1 RYR2 NALF1 KCNQ5 ATRNL1 SNTG1 UNC80 PHTF1	1.33e-07	198	131	8	0ff30edfd3c133a42e8cb96e1631a1143215f808
ToppCell	Cerebellum-Neuronal\|Cerebellum / BrainAtlas - Mouse McCarroll V32	RAB9B NYAP2 HECW1 ZFYVE28 ZNF644 NDRG4 UNC80	1.38e-06	187	131	7	61b9d6eb131a674598aa8409d7fa909c8765442d
ToppCell	Fetal_29-31_weeks-Mesenchymal-myofibroblast_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ADAMTS1 ZNF521 ATRNL1 PLXNA4 NHS UNC13C UNC80	1.38e-06	187	131	7	c104fbfef2d0bef64077ac721edf2379fd59d547
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	EXPH5 ICA1 NALF1 HMCN1 SNX10 UNC13C NR3C2	1.43e-06	188	131	7	eec3d353e51358db4c7621265ee0fdd4298e5b0e
ToppCell	Mesenchymal-myofibroblast_cell\|World / Lineage, Cell type, age group and donor	ADAMTS1 ZNF521 ATRNL1 PLXNA4 NHS UNC13C UNC80	1.49e-06	189	131	7	44e37f88137bb249933eb615235b2cf2ae7f3925
ToppCell	10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_arterial-C\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	FILIP1 ABCA4 ADAMTS1 RTEL1 ZIC4 BCAM PLXNA2	1.54e-06	190	131	7	06bfb62b94b0faf467ef93d5bc5d08924c770098
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN EXPH5 PRRT2 UNC13C CACNA1G NDRG4 UNC80	1.71e-06	193	131	7	5fb7808dd971c1cc64c2bd4f8f1de646fb2d77f4
ToppCell	Neuronal\|World / cells hierarchy compared to all cells using T-Statistic	ICA1 RYR2 NALF1 KCNQ5 ATRNL1 SNTG1 UNC80	2.16e-06	200	131	7	48d801219bc771d6c7e151dc88ca4c179988de85
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-1M-Radial_glial-gliogenic/outer_RGCs_and_astrocytes\|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.	STARD13 NPR3 HIPK3 PER2 SNTG1 DLX3	7.16e-06	157	131	6	2c1219ee19a6246a3b9f5c2c1a37f26ea934a822
ToppCell	Influenza_Severe-cDC\|Influenza_Severe / Disease group and Cell class	RAB9B NPR3 ZNF521 FRRS1 ADAMDEC1 NECTIN4	9.84e-06	166	131	6	b40bdf0f7f381e25be61188e9f6c294d25a8b824
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_B-Branch_B2_(eMN)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NYAP2 ICA1 HOXB5 SNX10 MAP7D2 NDRG4	1.51e-05	179	131	6	d96741c5c551e36421b2ad938072ab7d506c3835
ToppCell	3'-Distal_airway-Immune_Lymphocytic-Lymphocytic_T/NK-CD4-positive,_alpha-beta_T_cell-CD4_T_cells-CD4_T_cells_L.1.1.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NYAP2 FANCM ZNF831 ZNF81 MAPKBP1 PHTF1	1.51e-05	179	131	6	6bbb32d7e582a96cb3cfc3eb911b05d518e7d5e9
ToppCell	368C-Endothelial_cells-Endothelial-E\|368C / Donor, Lineage, Cell class and subclass (all cells)	NPR3 RTEL1 ICA1 LAMA5 UNC13C BCAM	1.56e-05	180	131	6	8ab16a0b9053bffc07b569a4f9e71749f56dde7e
ToppCell	368C-Endothelial_cells-Endothelial-E-\|368C / Donor, Lineage, Cell class and subclass (all cells)	NPR3 RTEL1 ICA1 LAMA5 UNC13C BCAM	1.56e-05	180	131	6	394cd465b88429b70eebb2957480dffcbc51cfe7
ToppCell	Fetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	HECW1 ZNF521 ATRNL1 PLXNA4 UNC13C UNC80	1.61e-05	181	131	6	d7e04e0ca549eac6d9b1192b6578f9b54943d54f
ToppCell	5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	RAB9B ADAMTS1 RYR2 TRIM45 HOXB5 HMCN1	1.61e-05	181	131	6	b116c68393d8836bac080f81a8fcbeb52e0403e7
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_B-Branch_B1_(eMN)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NYAP2 ANK2 NEUROD4 CHAT HOXB5 KCNQ5	1.61e-05	181	131	6	7f99002a6411117cc2361334c7c9228e20c574b4
ToppCell	5'-GW_trimst-2-LargeIntestine-Neuronal-neurons_B-Branch_B1_(eMN)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NYAP2 RYR2 HOXB5 KCNQ5 NDRG4 UNC80	1.71e-05	183	131	6	7e2bac8b005155888ff4b41ef2e1d975dc17abc7
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	EXPH5 ICA1 HMCN1 SNX10 UNC13C NR3C2	1.71e-05	183	131	6	2e831a4d99c6f983793df71c0994124c943c6da9
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EXPH5 RYR2 ZIC4 NALF1 UNC13C UNC80	1.82e-05	185	131	6	cdd75abdaa1ecedfd2e636203b83a6ac1782f0c3
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	GPRIN3 KDM5D ZNF831 ZFYVE28 CCSER2 GOLGA8B	1.82e-05	185	131	6	f1263899a2d41d182022dc4ca62cbae08a463c89
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal-interneuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN EXPH5 PRRT2 ZFYVE28 UNC13C UNC80	1.88e-05	186	131	6	d1d01ce46e62944aa9864eda47e8401b5f0d2bdc
ToppCell	Substantia_nigra-Neuronal\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	RAB9B NYAP2 HECW1 MAP7D2 NDRG4 UNC80	1.88e-05	186	131	6	3f889083fcffe516388e9b03a5e23af2010ced33
ToppCell	5'-GW_trimst-2-LargeIntestine-Neuronal-neurons_B\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NYAP2 RYR2 HOXB5 KCNQ5 NDRG4 UNC80	1.88e-05	186	131	6	15f2e5905486e33f6f7b3b3e9758a0559e8c61ee
ToppCell	LV-10._Endothelium_II\|World / Chamber and Cluster_Paper	NPR3 NEDD4 NEDD9 NALF1 HMCN1 PLXNA2	1.93e-05	187	131	6	7876dcb4800c2e54874df3d933efb79307a64a97
ToppCell	ILEUM-inflamed-(3)_MNP-(3)_moDC\|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	ZFYVE16 GPRIN3 REV3L PRKD3 NHS MAPKBP1	1.93e-05	187	131	6	0099def970fbc828756fbf853eca2ce77b8cd342
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	FILIP1 NYAP2 LAMA5 PLEKHG4B GOLGA8B BCAM	1.93e-05	187	131	6	4ae7465174e0295d2c3b614b321a3b2f514dd22a
ToppCell	facs-Heart-LA-24m-Endothelial-endothelial_cell_of_endocardium\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPR3 ADAM10 FRRS1 ZBTB39 HMCN1 BCAM	1.93e-05	187	131	6	d9943e65eedab73d141eae524e2411653a751705
ToppCell	facs-Heart-LA-24m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPR3 ADAM10 FRRS1 ZBTB39 HMCN1 BCAM	1.93e-05	187	131	6	7b13c3b67d66f3afb410141d5471c9e78a4d8623
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-interneuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN EXPH5 PRRT2 NECTIN4 UNC13C UNC80	1.93e-05	187	131	6	1b2fdbfb1ce3f19795dfc4b1da5a94f4b057ec41
ToppCell	systemic_lupus_erythematosus-flare-Myeloid-plasmacytoid_dendritic_cell-male\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	ZFAT NACC1 ZNF521 KDM5D MAP7D2 UTY	1.93e-05	187	131	6	d3563bb087e476baea5b59389e4d34d0ff98cac5
ToppCell	LA-13._Vascular_Smooth_Muscle\|LA / Chamber and Cluster_Paper	RYR2 NEDD9 KCNQ5 NHS UNC13C LRRFIP1	1.99e-05	188	131	6	34e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	EXPH5 ICA1 NALF1 HMCN1 SNX10 NR3C2	1.99e-05	188	131	6	bc089cd73d283ed7d2ecbb3936673b4edc89f666
ToppCell	COVID-19-kidney-DCT\|kidney / Disease (COVID-19 only), tissue and cell type	ICA1 GPRIN3 NALF1 HMCN1 SNX10 NR3C2	1.99e-05	188	131	6	df1fd0819d301679f3c9ea404e942e39095912eb
ToppCell	facs-Pancreas-Endocrine-24m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN ANK2 INPP4A INSRR NISCH UNC80	1.99e-05	188	131	6	a91443aa8fa8fa87f7501c59219daa0305bd0bbf
ToppCell	COVID-19-T_cells-CD8+_T_cells\|COVID-19 / group, cell type (main and fine annotations)	RIPOR2 GPRIN3 ZNF831 ZFYVE28 KCNQ5 CCSER2	2.05e-05	189	131	6	2c018d6120f65f0b2704b483bc9da1c0984872e3
ToppCell	COVID-19-Heart-EC_(POSTN)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	NPR3 ZNF521 NALF1 HMCN1 PLXNA4 UNC13C	2.05e-05	189	131	6	7346c1112e2e155dbd71b6dbc80e680fd262a691
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	EXPH5 ICA1 HMCN1 SNX10 UNC13C NR3C2	2.05e-05	189	131	6	977a813e5d7a5a561c1fced2bbf21c20056b88d8
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	EXPH5 ICA1 NALF1 HMCN1 SNX10 NR3C2	2.05e-05	189	131	6	975c0f079903ae36b0ffa54e86294d42ec7697de
ToppCell	RA-10._Endothelium_II\|World / Chamber and Cluster_Paper	NPR3 PPEF1 NEDD9 NALF1 HMCN1 PLXNA2	2.05e-05	189	131	6	75c248b9de5e2fb7a0baa8cdbab516e575cc4394
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	EXPH5 ICA1 NALF1 HMCN1 SNX10 NR3C2	2.05e-05	189	131	6	7eb8f5a951e80f1cfac4d7c9eb169f4eb100c917
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTS1 NEDD9 NALF1 SNX10 NHS MAPKBP1	2.05e-05	189	131	6	8c8ca3b30d9be6c854615459a7bfba82b427c8bc
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN EXPH5 PRRT2 UNC13C NDRG4 UNC80	2.05e-05	189	131	6	f57200c93d39c9bce1adba0a6a1c178c028dd86b
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTS1 NEDD9 NALF1 SNX10 NHS MAPKBP1	2.05e-05	189	131	6	5d902a4660a27548764bf04c6de152b565da835c
ToppCell	COPD-Myeloid-ncMonocyte\|Myeloid / Disease state, Lineage and Cell class	NCOA2 RIPOR2 RIPK2 HERC2P3 WAC NEDD9	2.11e-05	190	131	6	ed978cd5d9da87b49878a330e362762c487f849f
ToppCell	Globus_pallidus-Neuronal\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	NYAP2 HECW1 PRRT2 RYR2 NDRG4 UNC80	2.11e-05	190	131	6	416de85d8841dac883faa6f5339b2fb461a09e82
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	EXPH5 ICA1 HMCN1 SNX10 UNC13C NR3C2	2.11e-05	190	131	6	e252e925600e6457fa6e362a55217f4cffa75cdb
ToppCell	facs-Pancreas-Endocrine-3m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FILIP1 EXPH5 USP9X INSRR LOXL2 UNC80	2.18e-05	191	131	6	f76f3f5c7902a3659d8cbe470f96ce57c8a6744d
ToppCell	COVID-19-T_cells\|COVID-19 / group, cell type (main and fine annotations)	RIPOR2 GPRIN3 ZNF831 ZFYVE28 KCNQ5 CCSER2	2.18e-05	191	131	6	7f64add931b64b8d35836fa6bee9ebab593844d3
ToppCell	COVID-19-Heart-EC_(POSTN)\|Heart / Disease (COVID-19 only), tissue and cell type	NPR3 ZNF521 NALF1 HMCN1 PLXNA4 UNC13C	2.24e-05	192	131	6	c0c34785a7bdf461722029b322e9184e3d9b3c26
ToppCell	facs-Pancreas-Endocrine-3m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FILIP1 EXPH5 USP9X INSRR LOXL2 UNC80	2.24e-05	192	131	6	5b7093d5af5ae7b0e6d3a464cc56272440ecedad
ToppCell	Entopeduncular-Neuronal\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	RAB9B NYAP2 HECW1 GPRIN3 NDRG4 UNC80	2.24e-05	192	131	6	4c35e5c28a40b439044797ba1f06cb7c36b2a8de
ToppCell	RV-10._Endothelium_II\|RV / Chamber and Cluster_Paper	NPR3 NEDD4 NEDD9 NALF1 HMCN1 PLXNA2	2.31e-05	193	131	6	01c2df9206f1527c578e808978e58196c35e72f5
ToppCell	droplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANK2 USP9X KIAA0232 INSRR NISCH UNC80	2.31e-05	193	131	6	471e65f02937bc18d7c5facdacdf1df58cf0f839
ToppCell	droplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANK2 USP9X KIAA0232 INSRR NISCH UNC80	2.31e-05	193	131	6	fe451b3295d77b2bd1ac25cf29310c85835a45fe
ToppCell	Thalamus-Neuronal\|Thalamus / BrainAtlas - Mouse McCarroll V32	RAB9B NYAP2 HECW1 SNTG1 MAP7D2 NDRG4	2.31e-05	193	131	6	712a4acd1167e43543950bc819ff11984e6f718d
ToppCell	5'-Adult-Appendix-Endothelial-blood_vessel_EC-Mature_venous_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ADAMTS1 LAMA5 HIPK3 NEDD9 NALF1 BCAM	2.31e-05	193	131	6	c0973a2c97deb7176c2f617c8760a55f7edc9839
ToppCell	LV-10._Endothelium_II\|LV / Chamber and Cluster_Paper	NPR3 ADAMTS1 NEDD9 NALF1 HMCN1 PLXNA2	2.38e-05	194	131	6	b6cc849fa08599bff9839ef382d190cc964e273e
ToppCell	390C-Epithelial_cells-Epithelial-I_(AT1)\|390C / Donor, Lineage, Cell class and subclass (all cells)	LAMA5 ITPRID2 PLEKHG4B BCAM KAT6B TP53BP1	2.38e-05	194	131	6	88db9f9e80c20ff3474f1f6459dcbdc25aec0b6d
ToppCell	390C-Epithelial_cells-Epithelial-I_(AT1)-\|390C / Donor, Lineage, Cell class and subclass (all cells)	LAMA5 ITPRID2 PLEKHG4B BCAM KAT6B TP53BP1	2.38e-05	194	131	6	a71728202493d4858342ea2756ea281cd0d99a3a
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NYAP2 HECW1 PRRT2 KCNQ5 NDRG4 UNC80	2.45e-05	195	131	6	ffbab350e67d9c4b66c0ab84550daec8b8139a27
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	EXPH5 ICA1 GPRIN3 HMCN1 SNX10 UNC13C	2.45e-05	195	131	6	a38d9dc6192aea673d96fda6b25e81223fda3abf
ToppCell	background-Endothelial_cells\|background / Sample and Cell Type and Tumor Cluster (all cells)	FILIP1 RELN RIPOR2 ICA1 ZNF521 ATRNL1	2.52e-05	196	131	6	e6fb0bfab1779ec64a8c35d01519eaafbf62e977
ToppCell	facs-Skin-Telogen-3m-Epithelial-bulge_keratinocyte\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KLF15 CHAT NEDD4 HMCN1 PLXNA2 LRRFIP1	2.52e-05	196	131	6	90edf61116ffcb4f8b6be3d0a05732d59b0a87d5
ToppCell	5'-Adult-LargeIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ZNF521 LAMA5 NEDD9 NALF1 HMCN1 BCAM	2.59e-05	197	131	6	87eda06344498dc66cac292cf89746dc90b5cf67
ToppCell	5'-GW_trimst-2-SmallIntestine-Neuronal-neurons_B\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NYAP2 ANK2 HOXB5 KCNQ5 DLX3 NDRG4	2.59e-05	197	131	6	a1ae1aa797762a3768e14434c7e5cd19c595ecb3
ToppCell	wk_08-11-Epithelial-Airway_epithelial_progenitor-epi-stalk_intermediate\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	EXPH5 ICA1 LAMA5 NEDD9 PLEKHG4B BCAM	2.74e-05	199	131	6	debdd7dba774d9ccff7effc3f4c132393d203dfa
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Parietal_and_Temporal-6\|World / Primary Cells by Cluster	NYAP2 ANK2 RYR2 PLXNA4 SNTG1 UNC13C	2.74e-05	199	131	6	1b1bccf4293f11048709d15a3c892c0edf3da3d2
ToppCell	wk_08-11-Epithelial-Airway_epithelial_progenitor\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	ICA1 LAMA5 NEDD9 PLEKHG4B NECTIN4 BCAM	2.74e-05	199	131	6	af664e0d41a889a75dbf6cf0d50acd26f5ab3a3a
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Parietal_and_Temporal\|World / Primary Cells by Cluster	NYAP2 ANK2 RYR2 PLXNA4 SNTG1 UNC13C	2.74e-05	199	131	6	4bee94c116c0da5eba951cb4cea7cc9dcdd6e30f
ToppCell	390C-Endothelial_cells-Endothelial-B_(Artery)-\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	NPR3 ADAMTS1 ITPRID2 NEDD9 CCSER2 PLXNA2	2.82e-05	200	131	6	c32ad15dede3f879007c0b856f2fed1f5b058103
ToppCell	distal-Endothelial-Capillary_Intermediate_1-2\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	STARD13 EXPH5 LAMA5 BCL3 NEDD9 NDRG4	2.82e-05	200	131	6	43bc48413b100a06f8edd9acd812296788fcbf5b
ToppCell	390C-Endothelial_cells-Endothelial-B_(Artery)\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	NPR3 ADAMTS1 ITPRID2 NEDD9 CCSER2 PLXNA2	2.82e-05	200	131	6	8a2c6c53a39fab86750526083f7254b7413b29af
ToppCell	distal-Endothelial-Capillary_Intermediate_1\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	STARD13 EXPH5 LAMA5 BCL3 NEDD9 NDRG4	2.82e-05	200	131	6	4d6714d48738cdee7d535923f6dd2431e5304741
ToppCell	Tracheal-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	HECW1 ZNF521 RYR2 HMCN1 ATRNL1 CACNA1G	2.82e-05	200	131	6	58b38f9a484ee94191091a0659ed62ebed2d4a14
ToppCell	COVID-19-kidney-Mito-rich_Int\|COVID-19 / Disease (COVID-19 only), tissue and cell type	RELN ZIC4 LOXL2 SNTG1 UNC13C	3.06e-05	122	131	5	a4220adb4e6055a599bd9bbf65d460fc4e68b543
ToppCell	metastatic_Lymph_Node-Endothelial_cells-Tumor_ECs\|Endothelial_cells / Location, Cell class and cell subclass	ZNF521 BCL3 BCAM PLXNA2 LRRFIP1	3.18e-05	123	131	5	de29861800d083e4977afbef59c1a81336824703
ToppCell	droplet-Lung-21m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l14\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ZFAT ALS2 PLEKHN1 SNX10 NECTIN4	4.79e-05	134	131	5	932b7dd5781b730dcd2ffe43f6e142e3f8630f67
ToppCell	droplet-Bladder-BLADDER-1m-Epithelial-nan\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZFAT INSRR KDM5D FANCM KCNQ5	5.90e-05	140	131	5	e442c46979d725ec82f525a001c46d971fcade4d
ToppCell	PND07-28-samps-Mesenchymal-Myofibroblast-MyoFB-3\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	ZFAT ANK2 PRRT2 AKAP4 CACNA1G	6.10e-05	141	131	5	7ae8ead02e5aeb4106c4a30c08a7a061da3a5d6a
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Chrna2_Ptgdr\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	STARD13 FILIP1 RELN NHS UNC13C	6.74e-05	144	131	5	71107275767a0728541a3695715c44874b3e5efc
ToppCell	COVID-19-Heart-CM_5_(RYR2-)\|Heart / Disease (COVID-19 only), tissue and cell type	FAM184B HECW1 KCNQ5 ATRNL1 UNC13C	9.55e-05	155	131	5	d7e26696fd9c0a759524f331243db43059b33ed9
ToppCell	normal-na-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-male\|normal / PBMC cell types (v2) per disease, treatment status, and sex	KDM5D CCSER2 ZFP69B UTY NDRG4	9.55e-05	155	131	5	08295584395e8d9cfc1b1648f98754b3ac53e587
ToppCell	Posterior_cortex\|World / BrainAtlas - Mouse McCarroll V32	HECW1 EXPH5 RYR2 KCNQ5 ROBO3	1.08e-04	159	131	5	18e9fe2efbe0bca7c3990f3b12b6f549e2c1263a
ToppCell	10x5'-blood-Lymphocytic_T_CD4-T_CD4/CD8\|blood / Manually curated celltypes from each tissue	GPRIN3 KDM5D ZNF831 NR3C2 UTY	1.17e-04	162	131	5	b4535bcb3f469bc139e73f1122f4070013e5a1de
ToppCell	COVID-19-kidney-Technical/muscle_(Imm)\|kidney / Disease (COVID-19 only), tissue and cell type	RELN ZNF831 RYR2 KCNQ5 SNTG1	1.21e-04	163	131	5	19c28ce16a588a7f4a035c32726f6ccd67702b5b
ToppCell	Basal_cells-Donor_03\|World / lung cells shred on cell class, cell subclass, sample id	RYR2 PLEKHG4B NALF1 NHS ZFP69B	1.24e-04	164	131	5	b15a26130a1ea1b370b6e3be21f02a0d6aaf6b3c
ToppCell	Influenza_Severe-cDC\|World / Disease group and Cell class	RAB9B NPR3 ZNF521 ADAMDEC1 NECTIN4	1.24e-04	164	131	5	c984228f73b9aa1aaf948541f64f41ed874770cd
ToppCell	Endothelial-B-IPF_01\|World / lung cells shred on cell class, cell subclass, sample id	RELN ABCA4 ANK2 ZNF521 ZNF831	1.32e-04	166	131	5	c286987ea4e511195607c87ec4529c2c2ed2122e
ToppCell	E16.5-Endothelial-Endothelial_lymphatic\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RELN ZNF521 ZNF235 ZNF831 HMCN1	1.35e-04	167	131	5	b93103a868fba63a8910bffb690a6242b9252833
Drug	Papaverine hydrochloride [61-25-6]; Down 200; 10.6uM; MCF7; HT_HG-U133A	STARD13 ZNF473 ADAM10 SETD2 PER2 BCAM MAPKBP1 LRRFIP1	1.64e-05	196	129	8	6245_DN
Drug	Ribavirin [36791-04-5]; Up 200; 16.4uM; MCF7; HT_HG-U133A	INPP4A ICA1 ZNF235 RYR2 HIPK3 AKAP4 LOXL2 KAT6B	1.64e-05	196	129	8	6018_UP
Drug	Diphemanil methylsulfate [62-97-5]; Down 200; 10.2uM; MCF7; HT_HG-U133A	NCOA2 RTEL1 INPP4A HIPK3 PRKD3 CCSER2 BCAM MAPKBP1	1.64e-05	196	129	8	1494_DN
Drug	Tinidazole [19387-91-8]; Up 200; 16.2uM; PC3; HT_HG-U133A	RIPOR2 KLF15 CHAT HUWE1 ADAMDEC1 ATRNL1 CD33 LOXL2	1.70e-05	197	129	8	3813_UP
Drug	Laudanosine (R,S) [1699-51-0]; Down 200; 11.2uM; MCF7; HT_HG-U133A	NCOA2 ZNF473 INPP4A ZFP69B KAT6B UTY GOLGA2 PHTF1	1.83e-05	199	129	8	7030_DN
Drug	Isopyrin hydrochloride [18342-39-7]; Down 200; 14.2uM; PC3; HT_HG-U133A	NPR3 ADAM10 RYR2 HOXB5 SETD2 UTY GOLGA2 PHTF1	1.83e-05	199	129	8	5879_DN
Disease	Malignant neoplasm of breast	NCOA2 ABCA4 ANK2 ADAMTS1 ADAM10 WDR53 NEDD4 SETD2 PER2 LOXL2 ZNF644 NISCH MAP7D2 NHS HERC2 KAT6B GEN1 TP53BP1 LRRFIP1	9.24e-08	1074	122	19	C0006142
Disease	very low density lipoprotein cholesterol measurement, cholesterol:total lipids ratio	ANKRD31 NYAP2 BCL3 ADAM10 ZNF106 ZNF335 BCAM TP53BP1	4.18e-06	222	122	8	EFO_0008317, EFO_0020943
Disease	Alzheimer disease	ANKRD31 RELN HECW1 ADAMTS1 ICA1 BCL3 PRKD3 NALF1 CD33 CACNA1G BCAM	5.76e-06	485	122	11	MONDO_0004975
Disease	triglycerides to total lipids in medium VLDL percentage	ANKRD31 NYAP2 ZNF335 BCAM TP53BP1	6.46e-06	63	122	5	EFO_0022335
Disease	colorectal health	ZFAT ADAMTS1 EXPH5 RYR2 NEDD9 NALF1 HERC2	2.12e-05	201	122	7	EFO_0008460
Disease	triglycerides:total lipids ratio, low density lipoprotein cholesterol measurement	ANKRD31 NYAP2 ADAM10 ZNF106 BCAM TP53BP1	3.88e-05	150	122	6	EFO_0004611, EFO_0020947
Disease	very low density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio	ANKRD31 NYAP2 ADAM10 ZNF106 ZNF335 BCAM TP53BP1	1.18e-04	264	122	7	EFO_0008317, EFO_0020944
Disease	cholesterol to total lipids in medium VLDL percentage	ANKRD31 NYAP2 ZNF335 TP53BP1	1.37e-04	63	122	4	EFO_0022239
Disease	Alzheimer disease, family history of Alzheimer’s disease	ADAMTS1 BCL3 ADAM10 CD33 BCAM	1.40e-04	119	122	5	EFO_0009268, MONDO_0004975
Disease	diabetes mellitus (implicated_via_orthology)	ICA1 INSRR F7	1.67e-04	26	122	3	DOID:9351 (implicated_via_orthology)
Disease	free cholesterol to total lipids in small VLDL percentage	ANKRD31 NYAP2 BCAM TP53BP1	2.69e-04	75	122	4	EFO_0022287
Disease	cholesterol:total lipids ratio, low density lipoprotein cholesterol measurement	ANKRD31 NYAP2 ZNF106 BCAM TP53BP1	3.38e-04	144	122	5	EFO_0004611, EFO_0020943
Disease	triglycerides:total lipids ratio, very low density lipoprotein cholesterol measurement	ANKRD31 NYAP2 ADAM10 ZNF335 BCAM TP53BP1	3.56e-04	225	122	6	EFO_0008317, EFO_0020947
Disease	lymphocyte count	NCOA2 RIPOR2 ZFAT NYAP2 EXPH5 KIAA0232 INSRR GPRIN3 ZNF831 SETD2 ZNF469 CD33 ZNF644 NR3C2 TM2D1 PHTF1	3.57e-04	1464	122	16	EFO_0004587
Disease	phospholipids:total lipids ratio	ANKRD31 NYAP2 BCL3 ZNF335 BCAM TP53BP1	3.73e-04	227	122	6	EFO_0020946
Disease	very low density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio	ANKRD31 NYAP2 BCL3 ZNF335 BCAM TP53BP1	4.90e-04	239	122	6	EFO_0008317, EFO_0020945
Disease	Intellectual Disability	INPP4A PRRT2 TSEN2 WAC SETD2 KCNQ5 ZNF335 CACNA1G	5.57e-04	447	122	8	C3714756
Disease	free cholesterol in medium LDL measurement	ANKRD31 BCL3 BCAM	6.09e-04	40	122	3	EFO_0022268
Disease	VENTRICULAR TACHYCARDIA, CATECHOLAMINERGIC POLYMORPHIC, 1 (disorder)	ANK2 RYR2	7.47e-04	10	122	2	C1631597
Disease	Acute Confusional Senile Dementia	RELN ADAMTS1 ADAM10 CD33	7.73e-04	99	122	4	C0546126
Disease	Alzheimer's Disease, Focal Onset	RELN ADAMTS1 ADAM10 CD33	7.73e-04	99	122	4	C0750900
Disease	Alzheimer Disease, Early Onset	RELN ADAMTS1 ADAM10 CD33	7.73e-04	99	122	4	C0750901
Disease	Presenile dementia	RELN ADAMTS1 ADAM10 CD33	7.73e-04	99	122	4	C0011265
Disease	Alzheimer Disease, Late Onset	RELN ADAMTS1 ADAM10 CD33	7.73e-04	99	122	4	C0494463
Disease	Familial Alzheimer Disease (FAD)	RELN ADAMTS1 ADAM10 CD33	8.03e-04	100	122	4	C0276496
Disease	Alzheimer's Disease	RELN ADAMTS1 ADAM10 CD33	8.34e-04	101	122	4	C0002395
Disease	cholesteryl esters:total lipids ratio, intermediate density lipoprotein measurement	NYAP2 ZNF106 BCAM TP53BP1	8.97e-04	103	122	4	EFO_0008595, EFO_0020944
Disease	hair colour measurement	NYAP2 ZFYVE16 ADAMTS1 KLF15 REV3L ZNF831 ZNF469 UNC13C HERC2	1.06e-03	615	122	9	EFO_0007822
Disease	triglycerides to total lipids in medium LDL percentage	NYAP2 BCAM TP53BP1	1.17e-03	50	122	3	EFO_0022334
Disease	free cholesterol in LDL measurement	ANKRD31 BCL3 BCAM	1.17e-03	50	122	3	EFO_0022266
Disease	cholesteryl esters to total lipids in IDL percentage	NYAP2 BCL3 TP53BP1	1.17e-03	50	122	3	EFO_0022247
Disease	free cholesterol in large LDL measurement	ANKRD31 BCL3 BCAM	1.24e-03	51	122	3	EFO_0022176
Disease	triglycerides to total lipids in large LDL percentage	NYAP2 BCAM TP53BP1	1.24e-03	51	122	3	EFO_0022331
Disease	cholesterol to total lipids in small VLDL percentage	ANKRD31 NYAP2 BCAM	1.24e-03	51	122	3	EFO_0022242
Disease	Mental Retardation, X-Linked Nonsyndromic	HUWE1 ZNF81	1.28e-03	13	122	2	C3501611
Disease	very low density lipoprotein cholesterol measurement, phospholipids:total lipids ratio	ANKRD31 NYAP2 BCL3 ZNF106 BCAM TP53BP1	1.36e-03	291	122	6	EFO_0008317, EFO_0020946
Disease	interleukin 1 receptor antagonist measurement	EXPH5 CHAT SPAG16	1.39e-03	53	122	3	EFO_0004754
Disease	phospholipids in large LDL measurement	ANKRD31 BCL3 BCAM	1.39e-03	53	122	3	EFO_0022174
Disease	triglycerides to total lipids in very large VLDL percentage	ANKRD31 NYAP2 BCAM	1.39e-03	53	122	3	EFO_0022340
Disease	malignant pleural mesothelioma (is_marker_for)	NCOA2 SETD2	1.49e-03	14	122	2	DOID:7474 (is_marker_for)
Disease	memory performance	ZFAT ALS2 NEDD9 PLEKHG4B ZFYVE28 ZNF335 UNC13C	1.60e-03	409	122	7	EFO_0004874
Disease	cholesterol:total lipids ratio, intermediate density lipoprotein measurement	NYAP2 ZNF106 BCAM TP53BP1	1.63e-03	121	122	4	EFO_0008595, EFO_0020943
Disease	electrocardiography	NCOA2 NPR3 RIPOR2 NALF1 CACNA1G NR3C2 KAT6B NDRG4	1.66e-03	530	122	8	EFO_0004327
Disease	free cholesterol:total lipids ratio, high density lipoprotein cholesterol measurement	NPR3 NYAP2 BCL3 ADAM10 BCAM TP53BP1	1.67e-03	303	122	6	EFO_0004612, EFO_0020945
Disease	neurofilament light chain measurement	ADAMTS1 BCL3 GOLGA8B	1.71e-03	57	122	3	EFO_0009178
Disease	cholesterol in large LDL measurement	ANKRD31 BCL3 BCAM	1.71e-03	57	122	3	EFO_0021901
Disease	free cholesterol to total lipids in medium VLDL percentage	ANKRD31 NYAP2 TP53BP1	1.71e-03	57	122	3	EFO_0022284
Disease	employment status	KLF15 PLXNA4	1.72e-03	15	122	2	EFO_0005241
Disease	triglycerides to total lipids in small VLDL percentage	ANKRD31 NYAP2 BCAM	1.80e-03	58	122	3	EFO_0022338
Disease	pyroglutamine measurement	RELN ICA1 NALF1	1.80e-03	58	122	3	EFO_0005408
Disease	cholesterol in IDL measurement	ANKRD31 BCL3 BCAM	1.80e-03	58	122	3	EFO_0021899
Disease	Breast Carcinoma	NCOA2 ADAMTS1 ADAM10 SETD2 LOXL2 NISCH HERC2 TP53BP1	1.82e-03	538	122	8	C0678222
Disease	triglycerides to total lipids in small LDL percentage	NYAP2 BCAM TP53BP1	1.89e-03	59	122	3	EFO_0022337
Disease	free cholesterol to total lipids in very large VLDL percentage	ANKRD31 NYAP2 BCAM	1.89e-03	59	122	3	EFO_0022289
Disease	triglycerides:total lipids ratio, intermediate density lipoprotein measurement	NYAP2 ZNF106 BCAM TP53BP1	1.94e-03	127	122	4	EFO_0008595, EFO_0020947
Disease	preeclampsia, hypertension, pregnancy-induced	NPR3 ZNF831	1.96e-03	16	122	2	EFO_0000668, MONDO_0024664
Disease	level of Phosphatidylethanolamine (16:0_20:4) in blood serum	NYAP2 ADAM10	1.96e-03	16	122	2	OBA_2045137
Disease	cholesterol to total lipids in IDL percentage	NYAP2 BCAM TP53BP1	1.99e-03	60	122	3	EFO_0022233
Disease	esterified cholesterol measurement	ANKRD31 NYAP2 BCL3 BCAM	2.00e-03	128	122	4	EFO_0008589
Disease	amino acid measurement	NYAP2 ZFYVE16 RYR2 NISCH SHPRH UNC13C NR3C2 BCAM PLXNA2	2.07e-03	678	122	9	EFO_0005134
Disease	free cholesterol in very large VLDL measurement	ANKRD31 NYAP2 TP53BP1	2.08e-03	61	122	3	EFO_0022274
Disease	free cholesterol in VLDL measurement	BCL3 BCAM TP53BP1	2.08e-03	61	122	3	EFO_0022276
Disease	sexual dimorphism measurement	ANKRD31 FILIP1 FAM184B NPR3 ZFAT NYAP2 BCL3 LOXL2 ZNF335 SNX10 MAPKBP1 TP53BP1	2.14e-03	1106	122	12	EFO_0021796
Disease	triglycerides to total lipids in IDL percentage	NYAP2 BCAM TP53BP1	2.29e-03	63	122	3	EFO_0022329
Disease	osteoarthritis	RELN HECW1 ATRNL1 MINAR1 SPAG16	2.34e-03	222	122	5	MONDO_0005178
Disease	Age-related macular degeneration	ABCA4 HMCN1	2.48e-03	18	122	2	cv:C0242383
Disease	glycine measurement	NYAP2 KLF15 UNC80 TP53BP1	2.56e-03	137	122	4	EFO_0009767
Disease	severe acute respiratory syndrome, COVID-19	NCOA2 RELN USP9X ZFYVE28 NALF1 GOLGA8B UNC13C	2.63e-03	447	122	7	EFO_0000694, MONDO_0100096
Disease	Profound Mental Retardation	INPP4A PRRT2 TSEN2 CACNA1G	2.70e-03	139	122	4	C0020796
Disease	Mental Retardation, Psychosocial	INPP4A PRRT2 TSEN2 CACNA1G	2.70e-03	139	122	4	C0025363
Disease	Mental deficiency	INPP4A PRRT2 TSEN2 CACNA1G	2.70e-03	139	122	4	C0917816
Disease	total lipids in small VLDL	ANKRD31 BCL3 TP53BP1	2.72e-03	67	122	3	EFO_0022148
Disease	cholesterol to total lipids in very small VLDL percentage	NYAP2 BCAM TP53BP1	2.72e-03	67	122	3	EFO_0022245
Disease	free cholesterol in large VLDL measurement	ANKRD31 NYAP2 TP53BP1	2.84e-03	68	122	3	EFO_0022265
Disease	triglycerides to total lipids in very small VLDL percentage	NYAP2 BCAM TP53BP1	2.96e-03	69	122	3	EFO_0022341
Disease	diverticular disease	KIAA0408 STARD13 HECW1 NALF1 NISCH	3.05e-03	236	122	5	EFO_0009959
Disease	sucrose liking measurement	RELN GOLGA8B	3.07e-03	20	122	2	EFO_0010157
Disease	family history of Alzheimer’s disease	BCL3 ADAM10 BCAM	3.21e-03	71	122	3	EFO_0009268
Disease	cholesteryl esters to total lipids in very small VLDL percentage	NYAP2 BCAM TP53BP1	3.21e-03	71	122	3	EFO_0022259
Disease	alkaline phosphatase measurement	NCOA2 DLG5 RIPOR2 ELP5 KLF15 WAC UNC13C NR3C2 BCAM TP53BP1 PHTF1	3.30e-03	1015	122	11	EFO_0004533

Protein segments in the cluster

Peptide	Gene	Start	Entry
GNKCDLSLSGGESSS	ARMT1	191	Q9H993
SSPSHTTNGCQGEKV	C2orf69	221	Q8N8R5
GSAEKECTSPSHSEL	C2orf78	696	A6NCI8
GLSKEQAPDCSSSDG	NEDD9	606	Q14511
SKGFSTTCPAHVDDL	ABCA4	1181	P78363
PSTSTCKHKVGDTEG	AKAP4	131	Q5JQC9
ENHSGSKTPVLLSCS	ALS2	651	Q96Q42
SPHDSGTECTPGESK	ADAM10	391	O14672
GSDHCPVGAVLSVSS	APEX2	301	Q9UBZ4
PSHDGSSFKSPDTVC	DBF4	121	Q9UBU7
ISSSLSCHAGSKDSP	DLX3	16	O60479
SCHAGSKDSPTLPES	DLX3	21	O60479
EHTNSSPCKSSGGLE	NPR3	466	P17342
HTIDLNSGSKAGSSC	RAB9B	186	Q9NP90
TFGEDSKHCPDAAST	ADAMTS1	491	Q9UHI8
DPLCSGDSTSANKTG	EDC4	51	Q6P2E9
HSTCLSEGALSPDGT	EDC4	296	Q6P2E9
AGSCTSKKGNPDSHA	INPP4A	566	Q96PE3
CTTPSSGHAASGKDS	KAT6B	381	Q8WYB5
SDKCLPHTSGSQVDT	ZFYVE28	631	Q9HCC9
SSSSLPHCLVSEGKE	ANK2	2846	Q01484
CTLDGFPKSRHSDGT	ANKRD31	1526	Q8N7Z5
STKHSCSGTSFKGNP	NR3C2	431	P08235
NDGHLVSSPAICSGS	NEDD4	136	P46934
GPGGHDACDKLSTST	MAP7D2	156	Q96T17
EDHCSSPGGTPASKS	HERC2	1361	O95714
SESDSSPRQGGDHSC	HECW1	656	Q76N89
GTLEPGHSKNLTCSV	CD33	151	P20138
HTCSPTKKEQGEASS	KCNQ5	401	Q9NR82
ASSQCPGDSKDHIIA	FAM184B	766	Q9ULE4
SGASCSKSRPHLAGT	FANCM	1791	Q8IYD8
LQHKDSGSSAACPSL	KDM5D	1511	Q9BY66
TGTEAHISSCKLGPQ	LOXL2	266	Q9Y4K0
AKSEHNPSTSGCSSD	PER2	86	O15055
SCSTSEHRLGKDSPS	PLXNA2	1781	O75051
SCSTSEHRLGKDSPS	PLXNA4	1781	Q9HCM2
PSHTKGSLLQCAASD	KIAA0232	951	Q92628
GDGDSSHLPAKKSCD	DLG5	1081	Q8TDM6
DLKPCDTSSTHTGSI	KIAA0408	471	Q6ZU52
CTSPGQGKDHKDLST	PRKD3	541	O94806
LTPGHKTSCDSLDLS	EXPH5	866	Q8NEV8
FTGSGKCPQKDHTST	EXPH5	1456	Q8NEV8
KCPQKDHTSTAVGDG	EXPH5	1461	Q8NEV8
TTTSGGCHSPEDEQK	GOLGA6L6	86	A8MZA4
TSGGCHSPEDEQKAS	GOLGA6L22	51	H0YM25
SHSSKLPVTVGFSGC	LAMA5	3476	O15230
TLLAGNHSSEPKVSC	NYAP2	601	Q9P242
KNGSNPETTTSGGCH	GOLGA2	51	Q08379
SGGCHSPEDTPKDNA	GOLGA2	61	Q08379
CDTVDGSPTSDSSGH	HIPK3	946	Q9H422
SKSCGSSSHENRPLD	HUWE1	3256	Q7Z6Z7
GTKQSTCSPGDHIIE	ITPRID2	606	P28290
PGATVKHSCQSDGNS	RELN	376	P78509
AHSLTLECKAAGNPS	HMCN1	1656	Q96RW7
PFSGHTTKCEADSSV	PRR35	511	P0CG20
PCTNGDSHGAKPSAS	HOXB5	101	P09067
DLSLSPGGESKANCS	PRRT2	86	Q7Z6L0
ECTKHTSGNNLVSPD	CCSER2	476	Q9H7U1
AVSCLDSGSQPHLGT	CACNA1G	2271	O43497
VSHLTKPFSASDCGN	FRRS1	186	Q6ZNA5
PAACSHDGKLLSSDV	DIS3L	41	Q8TF46
HSSKCTNINSDSPVG	BORA	126	Q6PGQ7
SGHGKCTTSVSVPSQ	ATRNL1	216	Q5VV63
GSRSSEKHSPDSACS	MAPKBP1	986	O60336
AAGEPCAKTTFSGHT	INSRR	186	P14616
SGSDCTSHLSKDLPG	GEN1	711	Q17RS7
DLDACSQLSAGPHKS	KLF15	166	Q9UIH9
SHQDSCPGDSSSVGK	ELP5	146	Q8TE02
SSPETAASGGCHSSE	GOLGA8B	41	A8MQT2
LSDSCGSISKADHSG	GPRIN3	511	Q6ZVF9
GKSVILDCTPTGTHD	BCAM	46	P50895
SGADSSLKNCHNDTP	BCL3	331	P20749
PHGTTSSCKQDDLLS	GJB5	231	O95377
ASRPLCSGGHASNKE	RYR2	2986	Q92736
GTVASCPLGHSDDTV	LRRFIP1	436	Q32MZ4
TSPSKEVTICGDLHG	PPEF1	161	O14829
LSALDKGSTHTACSG	ICA1	326	Q05084
KGSTHTACSGPIDEL	ICA1	331	Q05084
GSLSQLHKSDCDSSP	MINAR1	546	Q9UPX6
SLATGPEQSDICHTG	C8orf17	16	Q9NRJ1
GSPGEEQAHSCSTLS	RTEL1	846	Q9NZ71
GSGCHPTTESFEKSV	TSEN2	196	Q8NCE0
CLDHAKLGESSLSPS	USP9X	1061	Q93008
GLHKSQSSCLSGPNE	UTY	591	O14607
VPETSRHTGDTSNGC	UTY	676	O14607
SEPEVCSIHSESSGG	STARD13	191	Q9Y3M8
SEHSSSGVSTPCLKE	STARD13	336	Q9Y3M8
TSGTALGNSGKTHCP	TRIM45	16	Q9H8W5
ETLSSSHQKCPQLGG	PLEKHN1	586	Q494U1
QGGESASDGHISCPK	FILIP1	6	Q7Z7B0
PLTGSSHCDSELSLN	NHS	656	Q6T4R5
QSSGTSSPLCDSGLH	SNTG1	161	Q9NSN8
SKDSCKGDSGGPHAT	F7	396	P08709
DSQGHCPATSDSGIT	SHPRH	596	Q149N8
GSRPQACTHSESSEG	NDRG4	326	Q9ULP0
KESTSGDKPVSHSCT	WAC	306	Q9BTA9
KDEDHCSSPGGTPAS	HERC2P3	86	Q9BVR0
GDEETECQSSPKHSS	TRPT1	231	Q86TN4
LPNGDCALTSHSTGS	RIPOR2	436	Q9Y4F9
DPANHTCGVKSTDGK	ADAMDEC1	181	O15204
SHSIPTDCAKGQLSG	CHAT	251	P28329
TTGQAESSCHPGEQK	NCOA2	596	Q15596
GGDTITHQPDSCKAA	ZFAT	691	Q9P243
QSDSISPKATISGCH	UNC80	276	Q8N2C7
SSPAHCSTPGDAGKD	UNC80	2766	Q8N2C7
LEPGFSSSGCISQTH	UNC13C	226	Q8NB66
SKHSETCSPGNTASE	REV3L	1436	O60673
SPDCSLGDTQHGEKL	SPATA46	71	Q5T0L3
SNKGTETDNDPSCVH	PHTF1	216	Q9UMS5
DSCQPDHTSVFSKGL	PLEKHG4B	741	Q96PX9
CGSSQLHENSGSPET	RIPK2	346	O43353
SHLTEPSSSGGCLVT	ROBO3	1121	Q96MS0
PSSKDQTSPSHGEGC	ZNF521	91	Q96K83
CFHPSGDKLATSSGD	SPAG16	401	Q8N0X2
PTCASGDAKTDLGHI	NISCH	166	Q9Y2I1
PNITCKDSSGNETHF	TM2D1	86	Q9BX74
EGGCSLASTPATTLH	TP53BP1	326	Q12888
TGGHSSPVLCLNASK	WDR53	6	Q7Z5U6
HSFSLQTPCSKGSEL	SETD2	586	Q9BYW2
GKTELSFSSSCEIPH	SETD2	1231	Q9BYW2
DSSSHGCKVNTAPQE	SNX10	186	Q9Y5X0
CLSNSEHSKDPGFGQ	ZBTB39	276	O15060
SAVTCTHSGDTPKDS	ZNF469	2206	Q96JG9
TFHKGSATKPAGCQS	ZNF469	3636	Q96JG9
NPDKCGEESSPVHTS	ZNF644	366	Q9H582
LVSPSSDCGHKSQVA	ZIC4	306	Q8N9L1
ECGKAFSQSSSLIPH	ZFP69B	311	Q9UJL9
ECGKAFSDSSSLTPH	ZNF483	471	Q8TF39
GACPASADLKHSDGT	SYCN	21	Q0VAF6
THTGEKPCSSNTSKG	ZNF625	286	Q96I27
KDISPSAGEHGDCTT	ZNF831	1396	Q5JPB2
SPAKTHCVGDSQSSA	ZNF335	976	Q9H4Z2
HSNSDCGKDTLKVSP	ZNF235	236	Q14590
EPTKGNSGSEACTSS	ZNF106	1296	Q9H2Y7
SSHPTSIVKAGSCGE	USP33	521	Q8TEY7
TLEGEAPHQSCSDGK	ZNF81	81	P51508
PTGSNLKSNHSDECT	ZFYVE16	816	Q7Z3T8
DIATNGESPTECKSH	ZNF473	136	Q8WTR7
NNPSKGTVEKSGSCH	NALF1	386	B1AL88
LKVSSPSCDSQGLHA	NACC1	121	Q96RE7
SLGESSFGSHLPDCS	NEUROD4	231	Q9HD90
EGHPDSLKDNSSCSV	NECTIN4	421	Q96NY8