Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
MousePhenodecreased bone mineral density of lumbar vertebrae

ZBTB40 TWSG1

1.25e-053292MP:0021190
MousePhenodecreased bone trabecula number

ZBTB40 MECOM TWSG1 NLRP3

1.25e-0570294MP:0010869
MousePhenodecreased bone mineral density of presacral vertebrae

ZBTB40 TWSG1

2.49e-054292MP:0021188
MousePhenoskin hyperplasia

RHBDF2 TBK1

1.15e-048292MP:0001214
MousePhenoabnormal skin cell number

RHBDF2 TBK1

1.15e-048292MP:0001213
MousePhenoabnormal bone trabecula morphology

ZBTB40 MECOM TWSG1 NLRP3

1.59e-04134294MP:0010867
MousePhenoabnormal intervertebral disk development

NELL1 TWSG1

2.26e-0411292MP:0005229
MousePhenodecreased trabecular bone volume

ZBTB40 MECOM TWSG1

2.54e-0460293MP:0010879
MousePhenodecreased bone mineral density of vertebrae

ZBTB40 TWSG1

2.71e-0412292MP:0021186
MousePhenowhite adipose tissue inflammation

RHBDF2 NLRP3

3.20e-0413292MP:0031602
MousePhenoabnormal intervertebral disk morphology

NELL1 MECOM TWSG1

3.52e-0467293MP:0004173
MousePhenoruptured lens capsule

TDRD7 PXDN

3.72e-0414292MP:0008841
MousePhenoabnormal symphysis morphology

NELL1 MECOM TWSG1

4.17e-0471293MP:0030877
MousePhenodecreased trabecular bone connectivity density

ZBTB40 MECOM

4.90e-0416292MP:0010933
MousePhenoadipose tissue inflammation

RHBDF2 NLRP3

6.23e-0418292MP:0020386
MousePhenothin neurocranium

NELL1 TWSG1

6.23e-0418292MP:0030279
MousePhenoabnormal cartilaginous joint morphology

NELL1 MECOM TWSG1

7.07e-0485293MP:0030875
MousePhenoabnormal lens capsule morphology

TDRD7 PXDN

7.71e-0420292MP:0003236
MousePhenodecreased trabecular bone mass

ZBTB40 NLRP3

7.71e-0420292MP:0010873
MousePhenoslow postnatal weight gain

MECOM KDM5B RHBDF2 NLRP3

8.00e-04205294MP:0008489
DomainVWC

NELL1 VWF PXDN

1.60e-0528333PF00093
DomainVWFC_1

NELL1 VWF PXDN

3.45e-0536333PS01208
DomainVWC

NELL1 VWF PXDN

4.06e-0538333SM00214
DomainVWFC_2

NELL1 VWF PXDN

4.06e-0538333PS50184
DomainVWF_dom

NELL1 VWF PXDN

5.50e-0542333IPR001007
DomainEGF_3

NELL1 STAB1

1.98e-0412332PF12947
DomainEGF_dom

NELL1 STAB1

1.98e-0412332IPR024731
DomainVWC_out

NELL1 VWF

5.08e-0419332SM00215
DomainEGF_extracell

NELL1 STAB1

5.03e-0360332IPR013111
DomainEGF_2

NELL1 STAB1

5.03e-0360332PF07974
DomainLIM

PRICKLE2 WTIP

6.60e-0369332PF00412
Domain-

PRICKLE2 WTIP

6.78e-03703322.10.110.10
DomainLIM_DOMAIN_2

PRICKLE2 WTIP

6.97e-0371332PS50023
DomainZnf_LIM

PRICKLE2 WTIP

6.97e-0371332IPR001781
DomainLIM_DOMAIN_1

PRICKLE2 WTIP

6.97e-0371332PS00478
DomainLIM

PRICKLE2 WTIP

6.97e-0371332SM00132
Pubmed

METTL3-Mediated lncRNA m6A Modification in the Osteogenic Differentiation of Human Adipose-Derived Stem Cells Induced by NEL-Like 1 Protein.

NELL1 METTL3

8.73e-07233234505967
Pubmed

ASK1 inhibition reduces cell death and hepatic fibrosis in an Nlrp3 mutant liver injury model.

NLRP3 MAP3K5

8.73e-07233231996485
Pubmed

TBK1-METTL3 axis facilitates antiviral immunity.

METTL3 TBK1

8.73e-07233235172162
Pubmed

Activation of osteoblast ferroptosis via the METTL3/ASK1-p38 signaling pathway in high glucose and high fat (HGHF)-induced diabetic bone loss.

METTL3 MAP3K5

8.73e-07233235104016
Pubmed

METTL3-deficiency m6A-dependently degrades MALAT1 to suppress NLRP3-mediated pyroptotic cell death and inflammation in Mycobacterium tuberculosis (H37Ra strain)-infected mouse macrophages.

METTL3 NLRP3

2.62e-06333238458103
Pubmed

Neutrophil NLRP3 promotes cardiac injury following acute myocardial infarction through IL-1β production, VWF release and NET deposition in the myocardium.

VWF NLRP3

2.62e-06333238914598
Pubmed

TBK1 and IKKε act like an OFF switch to limit NLRP3 inflammasome pathway activation.

NLRP3 TBK1

2.62e-06333234518217
Pubmed

ASK1/p38‑mediated NLRP3 inflammasome signaling pathway contributes to aberrant retinal angiogenesis in diabetic retinopathy.

NLRP3 MAP3K5

2.62e-06333233416127
Pubmed

Lysine 63-linked TANK-binding kinase 1 ubiquitination by mindbomb E3 ubiquitin protein ligase 2 is mediated by the mitochondrial antiviral signaling protein.

MIB2 TBK1

2.62e-06333225142606
Pubmed

Verapamil Attenuated Prediabetic Neuropathy in High-Fat Diet-Fed Mice through Inhibiting TXNIP-Mediated Apoptosis and Inflammation.

NLRP3 MAP3K5

8.72e-06533230733849
Pubmed

Cutting edge: TLR signaling licenses IRAK1 for rapid activation of the NLRP3 inflammasome.

NLRP3 TBK1

1.83e-05733224043892
Pubmed

B cell-intrinsic MyD88 signaling controls IFN-γ-mediated early IgG2c class switching in mice in response to a particulate adjuvant.

NLRP3 TBK1

1.83e-05733231087643
Pubmed

m(6)A methyltransferase METTL3 relieves cognitive impairment of hyperuricemia mice via inactivating MyD88/NF-κB pathway mediated NLRP3-ASC-Caspase1 inflammasome.

METTL3 NLRP3

1.83e-05733236461592
Pubmed

ASK Family Kinases Are Required for Optimal NLRP3 Inflammasome Priming.

NLRP3 MAP3K5

1.83e-05733229353059
Pubmed

TACC1-chTOG-Aurora A protein complex in breast cancer.

TDRD7 MECOM

2.44e-05833214603251
Pubmed

DNA released from dying host cells mediates aluminum adjuvant activity.

NLRP3 TBK1

4.78e-051133221765404
Pubmed

RNA is an Adjuvanticity Mediator for the Lipid-Based Mucosal Adjuvant, Endocine.

NLRP3 TBK1

6.77e-051333227374884
Pubmed

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.

ZBTB40 IGBP1 VWF TBK1 MAP3K5

9.96e-0549733523414517
Pubmed

MIND bomb 2 prevents RIPK1 kinase activity-dependent and -independent apoptosis through ubiquitylation of cFLIPL.

MIB2 TBK1

1.18e-041733233469115
Pubmed

The HECT type ubiquitin ligase NEDL2 is degraded by anaphase-promoting complex/cyclosome (APC/C)-Cdh1, and its tight regulation maintains the metaphase to anaphase transition.

PKN2 PXDN CDC16 ASTE1

1.42e-0428133424163370
Pubmed

Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.

ZBTB40 ARHGAP32 VWF RHBDF2 STAB1

1.63e-0455233510737800
Pubmed

Genome-wide, large-scale production of mutant mice by ENU mutagenesis.

TDRD7 PXDN

1.99e-042233210932192
Pubmed

ZBP1/DAI is an innate sensor of influenza virus triggering the NLRP3 inflammasome and programmed cell death pathways.

NLRP3 TBK1

2.58e-042533227917412
Pubmed

SPATA2 links CYLD to the TNF-α receptor signaling complex and modulates the receptor signaling outcomes.

MIB2 TBK1

3.99e-043133227307491
Pubmed

SILAC-based proteomics of human primary endothelial cell morphogenesis unveils tumor angiogenic markers.

VWF PXDN TBK1

5.91e-0417333323979707
Pubmed

New candidate genes identified for controlling mouse gonadal sex determination and the early stages of granulosa and Sertoli cell differentiation.

NELL1 VWF

6.66e-044033219864314
Pubmed

Hundreds of variants clustered in genomic loci and biological pathways affect human height.

ZNFX1 PKN2 ADAMTSL3

8.74e-0419833320881960
Pubmed

Comparison of substrate specificity of the ubiquitin ligases Nedd4 and Nedd4-2 using proteome arrays.

PKN2 TBK1 MAP3K5

9.40e-0420333319953087
CoexpressionGAUCHER_PBMC_YF_VAX_STAMARIL_UNKNOWN_AGE_7DY_UP

TDRD7 ZNFX1 RHBDF2 NLRP3 STAB1

2.61e-05292325M41140
CoexpressionGSE2770_IL12_VS_IL4_TREATED_ACT_CD4_TCELL_2H_DN

TDRD7 TWSG1 VWF TBK1

4.11e-05159324M6086
CoexpressionGSE19888_ADENOSINE_A3R_INH_VS_ACT_IN_MAST_CELL_DN

TDRD7 ZNFX1 VWF WDFY4

9.81e-05199324M7341
CoexpressionGSE20198_IL12_VS_IFNA_TREATED_ACT_CD4_TCELL_DN

TDRD7 KDM5B IGBP1 MAP3K5

9.81e-05199324M7374
CoexpressionGSE17721_CTRL_VS_CPG_4H_BMDC_DN

TDRD7 ZNFX1 IGBP1 TBK1

1.00e-04200324M3763
CoexpressionGSE26495_NAIVE_VS_PD1HIGH_CD8_TCELL_DN

RHBDF2 PLCXD2 TBK1 MAP3K5

1.00e-04200324M4656
CoexpressionINAMURA_LUNG_CANCER_SCC_DN

VWF ADAMTSL3

1.12e-0413322M1255
CoexpressionACEVEDO_LIVER_CANCER_UP

TDRD7 KDM5B ZNFX1 METTL3 IGBP1 VWF CDC16

1.41e-04972327M15709
ToppCellCOVID-19-Heart-Fib_+_EC_+_Pericyte|Heart / Disease (COVID-19 only), tissue and cell type

PRICKLE2 MECOM VWF PXDN ADAMTSL3

2.89e-0719233560b1312e84f6d6448365a952469c506c00b5fe93
ToppCellPCW_10-12-Hematologic_Myeloid-Hem_Myeloid_macrophage-im_macrophage_(16)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

RHBDF2 WDFY4 NLRP3 STAB1

8.47e-0617633498176bf3c961d5262593e2d5d002836adb010e13
ToppCell5'-Adult-LymphNode-Mesenchymal-fibroblastic-Transitional_Stromal_3_(C3+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PRICKLE2 PXDN ADAMTSL3 DZIP1L

9.46e-06181334ab66a89f316b935d9ba1277426d976b1e9e39757
ToppCellCOVID-19-Heart-Fib_+_EC_+_Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

MECOM VWF PXDN ADAMTSL3

9.67e-06182334fbd5e332df73bf7141c822fa67b76367dc962017
ToppCellPCW_10-12-Hematologic_Myeloid-Hem_Myeloid_macrophage|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

RHBDF2 WDFY4 NLRP3 STAB1

1.12e-05189334440c422369de1c49112d18cf8c506a2a3a81f6ba
ToppCellPCW_10-12-Hematologic_Myeloid-Hem_Myeloid_macrophage-im_immature_macrophage2_(0)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

RHBDF2 WDFY4 NLRP3 STAB1

1.15e-05190334e0b363f772817cfc6ab425430805c1cddcba23f0
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RHBDF2 WDFY4 NLRP3 STAB1

1.15e-05190334788ff9d8888d2dd25b7e1d7e0e5d57751ce86f19
ToppCellPCW_10-12-Hematologic_Myeloid-Hem_Myeloid_macrophage-im_immature_macrophage1_(2)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

RHBDF2 WDFY4 NLRP3 STAB1

1.17e-05191334c383ae386bc53e73a683a9543c7dfed2a65257c5
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RHBDF2 WDFY4 NLRP3 STAB1

1.17e-05191334baa70781633a3fe5bf987f9d8dff3884f5167e7f
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RHBDF2 WDFY4 NLRP3 STAB1

1.19e-0519233486d792682ba51696f503c79625dd20f87bcf651f
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RHBDF2 WDFY4 NLRP3 STAB1

1.19e-05192334d0ad6a205ad50a3c523fa68676996b289eabc5de
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RHBDF2 WDFY4 NLRP3 STAB1

1.22e-05193334bd08555f02db8bc903caacae57e80bb91e2556ce
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Immune-Myeloid|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RHBDF2 WDFY4 NLRP3 STAB1

1.22e-05193334f597fefc54327a1ad136e2f66b6e81cc5c761eb7
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RHBDF2 WDFY4 NLRP3 STAB1

1.22e-05193334374d0526a071e973c3f43b4564f78f6933bb67ed
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Immune|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RHBDF2 WDFY4 NLRP3 STAB1

1.24e-0519433496f16bcd393a0d3f8df479b172b5360ae5a1e663
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RHBDF2 WDFY4 NLRP3 STAB1

1.24e-05194334c95d5c4ad0210ebd672926558cc8331e6396a854
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Immune|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RHBDF2 WDFY4 NLRP3 STAB1

1.24e-051943340866ab6792cee274a71991d5c37a37f574ff446e
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Immune-Myeloid|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RHBDF2 WDFY4 NLRP3 STAB1

1.27e-0519533491a3c439f10c03c5d51d904f512b6a08040edc76
ToppCellPCW_10-12-Hematologic_Myeloid|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

RHBDF2 WDFY4 NLRP3 STAB1

1.27e-051953346352cd749091cfdbf5cce3c354fa57883cc513e8
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW08-Myeloid|GW08 / Sample Type, Dataset, Time_group, and Cell type.

RHBDF2 WDFY4 NLRP3 STAB1

1.29e-0519633491a8c4798572d6c1f03cef5e8e5464ed0046c7cf
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW08-Myeloid-Microglia|GW08 / Sample Type, Dataset, Time_group, and Cell type.

RHBDF2 WDFY4 NLRP3 STAB1

1.29e-0519633489a0ccd0684777927d99d5fc5b7c498f3f124250
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RHBDF2 WDFY4 NLRP3 STAB1

1.29e-05196334cbc727b55b6433a701b1a331028a49960fcee6ee
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RHBDF2 WDFY4 NLRP3 STAB1

1.32e-051973346ca6e17b7cc5f7ea8d4b6ca1ff670969bee65a45
ToppCellBronchial-NucSeq-Immune_Myeloid-Macrophage_other-Macrophage_intravascular|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

RHBDF2 WDFY4 NLRP3 STAB1

1.35e-05198334c7dbf24caae5c4ef285845d13055de9e07281bb3
ToppCellTracheal-NucSeq-Immune_Myeloid-Monocytic-Monocyte_CD14|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

RHBDF2 WDFY4 NLRP3 STAB1

1.37e-051993341413156b7be5373fd02bbe39ec50ccfe165fa6d1
ToppCell5'-GW_trimst-2-LargeIntestine-Hematopoietic-Myeloid|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RHBDF2 WDFY4 NLRP3 STAB1

1.37e-05199334f34c15df58fbdc6c90e30800e26fabbf828ad10b
ToppCellTracheal-NucSeq-Immune_Myeloid-Macrophage_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

RHBDF2 WDFY4 NLRP3 STAB1

1.37e-0519933498c0d57c247d39bc771d81f4387f8dd01222628e
ToppCellTracheal-NucSeq-Immune_Myeloid-Macrophage_alveolar-Macro_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

RHBDF2 WDFY4 NLRP3 STAB1

1.37e-05199334b818d46a39c8782188d82dc8931b8eec9d549dd1
ToppCellTracheal-NucSeq-Immune_Myeloid-Macrophage_other-Macro_AW_CX3CR1|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

RHBDF2 WDFY4 NLRP3 STAB1

1.37e-05199334744b63fba33b176ab7dde11646ccb313665505f7
ToppCellILEUM-inflamed-(7)_ACKR1+_endothelial_cells|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

NELL1 MECOM VWF PXDN

1.37e-051993345c799115a6e95bcd896e4ad10bd272705c9a4e2c
ToppCellTracheal-NucSeq-Immune_Myeloid-Macrophage_other-Macrophage_intermediate|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

RHBDF2 WDFY4 NLRP3 STAB1

1.37e-0519933454167894a16e975d0541cbe3e515bcfa183044f6
ToppCellBronchial-NucSeq-Immune_Myeloid-Macrophage_other|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

RHBDF2 WDFY4 NLRP3 STAB1

1.40e-0520033478d75d381cb2b9a4c9eb7c32a07b014eaee39195
ToppCellTracheal-NucSeq-Immune_Myeloid|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

RHBDF2 WDFY4 NLRP3 STAB1

1.40e-05200334ad7ae5106141669b353800fece833b3cd5bdccee
ToppCellBronchial-NucSeq-Immune_Myeloid-Monocytic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

RHBDF2 WDFY4 NLRP3 STAB1

1.40e-052003348872d5fa101d413fb43b4231d476878678543035
ToppCellTracheal-NucSeq-Immune_Myeloid-Macrophage_other|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

RHBDF2 WDFY4 NLRP3 STAB1

1.40e-05200334f3dc07a7cc8cf041da8fe610d21af595818cf2d8
ToppCellParenchymal-NucSeq-Immune_Myeloid-Macrophage_other|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

RHBDF2 WDFY4 NLRP3 STAB1

1.40e-05200334ad52b38df5c71f28829b04cd0e6b97f0f9f7610a
ToppCellTracheal-NucSeq-Immune_Myeloid-Monocytic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

RHBDF2 WDFY4 NLRP3 STAB1

1.40e-0520033448ce43a27e78b2883e588e1a63fa5352c2deeeb7
ToppCellParenchymal-NucSeq-Immune_Myeloid-Monocytic-Monocyte_CD14|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

RHBDF2 WDFY4 NLRP3 STAB1

1.40e-05200334b4277b6faa69f20974696c7c422311f5c89e3663
ToppCellHippocampus-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Lcn2_(Lcn2)-|Hippocampus / BrainAtlas - Mouse McCarroll V32

MECOM VWF RHBDF2

7.55e-051113333e38efb22c47506ef2e2c1e19c79450e11d0ce56
ToppCellHippocampus-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Lcn2_(Lcn2)--|Hippocampus / BrainAtlas - Mouse McCarroll V32

MECOM VWF RHBDF2

7.55e-051113339ba3590be8862c23b6e2917caed8bdbd9f9c2753
ToppCellHippocampus-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Lcn2_(Lcn2)|Hippocampus / BrainAtlas - Mouse McCarroll V32

MECOM VWF RHBDF2

7.55e-05111333cd84f2a9102a6eb63226ecde11d4ece54ff99b48
ToppCell356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0|356C / Donor, Lineage, Cell class and subclass (all cells)

ZBTB40 PLCXD2 ASTE1

9.76e-051213334ec70ad316942d9ade7bbdbf0e117e7c52b59d90
ToppCellprimary_visual_cortex-Non-neuronal-endothelial_cell-Endo-Endo_Cytl1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MECOM VWF RHBDF2

1.13e-04127333eee8e4a83f7de46807440d202d46eee7dd722001
ToppCellStriatum-Endothelial-ENDOTHELIAL_STALK|Striatum / BrainAtlas - Mouse McCarroll V32

MECOM VWF RHBDF2

1.41e-04137333d37f425b13bc046baa1f8619b98a16b936f88ff6
ToppCellStriatum-Endothelial-ENDOTHELIAL_STALK-Flt1_1|Striatum / BrainAtlas - Mouse McCarroll V32

MECOM VWF RHBDF2

1.41e-04137333306b11b3b9e5fd562d845fb5eaa4ac982864efce
ToppCellHippocampus-Endothelial-ENDOTHELIAL_STALK|Hippocampus / BrainAtlas - Mouse McCarroll V32

MECOM VWF RHBDF2

1.47e-0413933334398a6f21a1e670497655a7bb7f3cde9e117560
ToppCellHippocampus-Endothelial-ENDOTHELIAL_STALK-Flt1_2|Hippocampus / BrainAtlas - Mouse McCarroll V32

MECOM VWF RHBDF2

1.47e-04139333450c4152c9fe4ec503271bb3cf93739918c59509
ToppCellSmart-seq2-lymph_node_(Smart-seq2)-myeloid-myeloid_monocytic-intermediate_monocyte|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

NLRP3 DZIP1L STAB1

1.57e-041423339b39c778cfaf457303010f1b1cae8c0cd8fe5d1d
ToppCellPosterior_cortex-Endothelial-ENDOTHELIAL_STALK|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

MECOM VWF RHBDF2

1.60e-0414333335d3652680c4dddd293301595d813161c66e5673
ToppCellTracheal-NucSeq-Immune_Myeloid-Macrophage_other-Macro_interstitial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

WDFY4 NLRP3 STAB1

1.67e-04145333778655fffd73df101e656154a41b478a1b695116
ToppCellSmart-seq2-lymph_node_(Smart-seq2)-myeloid-myeloid_monocytic|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

NLRP3 DZIP1L STAB1

1.91e-04152333072daae0deb6cb92f126e4566f1d264cda9ed157
ToppCellChildren_(3_yrs)-Epithelial-basal_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

PRICKLE2 MECOM CYP2A7

2.11e-041573336ee2692f705bdd93ba523dffaf2f0cd921b47e28
ToppCellEntopeduncular-Endothelial-ENDOTHELIAL_STALK|Entopeduncular / BrainAtlas - Mouse McCarroll V32

MECOM VWF RHBDF2

2.23e-0416033304714d0b9bad4c11fa193ed168e2d84a4df39e2e
ToppCellprimary_visual_cortex-Non-neuronal-endothelial_cell-Endo-Endo_Ctla2a|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MECOM VWF RHBDF2

2.27e-04161333a60ef3f390f56bb05b687b17986fe6382f69f260
ToppCellprimary_visual_cortex-Non-neuronal-endothelial_cell-Endo|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MECOM VWF RHBDF2

2.31e-041623330bdb1e5ba33e162bec1acb28256c1405a7658ee5
ToppCellAT1_cells-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

PXDN WTIP PLCXD2

2.31e-04162333ae2ba4f21f6f6c512006fa531d670b88be7c04c9
ToppCellprimary_visual_cortex-Non-neuronal-endothelial_cell|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MECOM VWF RHBDF2

2.31e-041623335799a602ef8d83925907e8e34532428be7330228
ToppCellThalamus-Hematopoietic|Thalamus / BrainAtlas - Mouse McCarroll V32

WDFY4 NLRP3 STAB1

2.48e-0416633376d60ac7ac5d1eaf530f0c741d9c48e0bd58396b
ToppCellDendritic_Cells-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

RHBDF2 NLRP3 STAB1

2.48e-04166333fbeb74b98b58085de323f744b18d4a8f7b22d5d4
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Myeloid-Macrophage-macrophage,_alveolar|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

MECOM NLRP3 STAB1

2.48e-0416633328a44448a0b0d72459e8fe84ce5d666f16f514b3
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Myeloid-Macrophage|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

MECOM NLRP3 STAB1

2.48e-041663332a04915d534a83e65aa168435d6856125b5bdd78
ToppCellAdult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D231|Adult / Lineage, Cell type, age group and donor

PRICKLE2 VWF PXDN

2.52e-041673335af9127bae05768a5164d5708a4ad37edca99324
ToppCelldroplet-Bladder-BLADDER-1m-Hematologic-leukocyte|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WDFY4 NLRP3 STAB1

2.61e-04169333b46e446067c6425bd5b8ef7719aeecff5e861249
ToppCelldroplet-Bladder-BLADDER-1m-Hematologic|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WDFY4 NLRP3 STAB1

2.61e-041693335508b03fbf483fce7701d6c82c297ffda3b1ba05
ToppCellAdult-Endothelial-endothelial_cell_of_bronchial_vessel-D122|Adult / Lineage, Cell type, age group and donor

VWF WTIP COA7

2.66e-04170333a99cb3d21f8eb926886340ea99491e078e607648
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Myeloid-Macrophage-macrophage,_alveolar-Macro_c3-EREG|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

WDFY4 NLRP3 STAB1

2.66e-041703339ac1ef57f14418a5dd2aa16861c3df698c28f5ed
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRICKLE2 MECOM VWF

2.66e-0417033350c6c571591aa4b218caefe5778c570c809f567e
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRICKLE2 MECOM VWF

2.66e-041703338fe32dcf924d5f6665f7febbc9647d96b1e96f06
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRICKLE2 MECOM VWF

2.66e-041703333232db50b1a40f861e981a1b9c9073b81af9f832
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage-Monocyte-derived_macrophage_L.1.2.5.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RHBDF2 NLRP3 STAB1

2.71e-041713335e93c76ee60f9d0590ebb140812653a5e1369417
ToppCellNasal_Brush-Epithelial-Ionocytes|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

VWF PXDN PLCXD2

2.75e-04172333dd3a23dc78dc6939f41126f8d7bd23a2e4713647
ToppCellNasal_Brush-Epithelial-Ionocytes|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

VWF PXDN PLCXD2

2.75e-0417233304fabb40fa9357d8902f3b04adc15231626cd9f8
ToppCellE12.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

TDRD7 VWF WTIP

2.75e-041723333b9be685fcd1634498a603b692f5ac6ddd0de176
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTSL3 WTIP MAP3K5

2.99e-04177333a8625d14682183cf77cb51eaf11bc15a3528f586
ToppCell5'-Adult-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PRICKLE2 PXDN ADAMTSL3

2.99e-04177333bd602db857f37869ef76d14c05ef522c509f08ee
ToppCell5'-Adult-Appendix-Mesenchymal-myocytic-myofibroblast|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PRICKLE2 NELL1 PXDN

2.99e-04177333e65c0568dc5852108e9802273499bc7cf88fafab
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTSL3 WTIP MAP3K5

2.99e-041773333645e2f4a48283f290f85c49c3e79e3f58ac9aa6
ToppCell3'-Child09-12-SmallIntestine-Mesenchymal-fibroblastic-Stromal_4_(MMP1+)|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PXDN ADAMTSL3 DZIP1L

2.99e-04177333ac90e4ce5be304a5a7473736397327010f2d1999
ToppCelldroplet-Liver-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRICKLE2 PXDN WTIP

2.99e-041773338ef41ee5d63737b810ad7371b0437625e7e1badf
ToppCellfacs-Lung-3m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MECOM VWF STAB1

3.04e-041783339f59a9af232d77bb55603a7776dbf9749ea652f2
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

PRICKLE2 MECOM CYP2A7

3.04e-04178333f5ed4a6e3eb8056b1be1fb311021710c95bdf888
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_prolif-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TDRD7 WDFY4 STAB1

3.04e-0417833330d2b54462fd16222ad2e3806be6143e834b29e0
ToppCell368C-Myeloid-Macrophage-SPP1+_Macrophage_3|368C / Donor, Lineage, Cell class and subclass (all cells)

TDRD7 WDFY4 MAP3K5

3.04e-04178333536a601abcc60867949ea06e9aafb6c7b799b56b
ToppCelldroplet-Liver-LIVER_NPC-30m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZBTB40 MECOM ARHGAP32

3.09e-04179333025d414ec88d5680d99c8173e70ee3bb0b694f74
ToppCelldroplet-Lung-LUNG-30m-Endothelial-Artery_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MECOM VWF STAB1

3.09e-04179333a09647750eba9d93c5efc1db3b555fefb5eec7b5
ToppCell3'-GW_trimst-1.5-LargeIntestine-Hematopoietic-Myeloid-cDC2|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RHBDF2 WDFY4 NLRP3

3.09e-04179333ce95b601bf17ae8167d382a105384b9e65e9407f
ToppCellPND28-Immune-Immune_Myeloid-DC-cDC1-cDC1_prolif|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ARHGAP32 WDFY4 NLRP3

3.09e-041793339dea57494d59abd6e8abf34e31faf53462ea0fa0
ToppCellfacs-Lung-18m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MECOM VWF STAB1

3.15e-0418033367c5068b660cd5e727a665cefe3bd5f8ae887221
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MECOM TWSG1 ADAMTSL3

3.15e-04180333788d5fbf688365b5d92d3aa19b9f8e9448f8be5a
ToppCell3'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC-venous_capillary|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MECOM VWF STAB1

3.15e-0418033397e0dcb7cfbba60a782824c5e23995058609fcd4
ToppCell3'-GW_trimst-1.5-LargeIntestine-Hematopoietic-Myeloid|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RHBDF2 WDFY4 STAB1

3.20e-04181333090e89b506d945e123e647d08947e9649a65ce7c
ToppCelldroplet-Mammary_Gland-nan-18m-Endothelial-nan|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MECOM VWF STAB1

3.20e-041813332e15c46e8260bb04d8264478c19a707221996026
ToppCell11.5-Distal-Immune-Immune|Distal / Age, Tissue, Lineage and Cell class

TDRD7 WDFY4 NLRP3

3.20e-04181333193ee02f547a218b2fc13e1174ea4cff4f8a3450
ToppCelldroplet-Lung-3m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MIGA1 VWF STAB1

3.20e-041813332c44c41b4e8a75ebdbaeb0c6cc5a03f17c44758c
ToppCellfacs-Lung-18m-Endothelial-arterial_endothelial|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MECOM VWF STAB1

3.25e-04182333ebc812ed3f25839ea25f76b952c463d79a8325b1
ToppCellCOVID-19-Heart-EC_+_Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

MECOM VWF ADAMTSL3

3.25e-04182333e67f3234165199085c793915ebb1f9bbd845e933
ToppCellfacs-Lung-18m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MECOM VWF STAB1

3.25e-0418233347ff6b4002a4167412c79210651316d1342503f9
ToppCelldroplet-Lung-30m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MECOM VWF STAB1

3.30e-041833336f8f997ffc9eaebca2683de125b6069d07c07d26
ToppCell5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MECOM VWF PXDN

3.30e-04183333ce8be9418b473ea94ec806edc7a2078cc30c1703
ToppCellB_cells-ISG-high_B_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

TDRD7 ZNFX1 WDFY4

3.30e-04183333dc2b00e920efa1dcc2a6265cd1024e3249c9974f
Drugnt U

ARHGAP32 NLRP3 TBK1

6.24e-0625333CID000446223
Diseaseblood nickel measurement

PRICKLE2 PLCXD2 NLRP3

2.98e-04120323EFO_0007583
Diseaseornithine measurement

NELL1 MECOM

1.05e-0344322EFO_0009776
Diseasesitting height ratio

MECOM ADAMTSL3

1.41e-0351322EFO_0007118

Protein segments in the cluster

PeptideGeneStartEntry
SDKEHMCTVVYFDDC

TWSG1

161

Q9GZX9
KMHCCVAAYISDYAF

ACOT8

221

O14734
KCFSLDAFCHHFSNM

ASTE1

196

Q2TB18
MSHDSGKHYECENCA

MECOM

311

Q03112
HTCHLCDKTFMNATF

DZIP1L

166

Q8IYY4
CHCYHVAEFELPKTM

IGBP1

116

P78318
LHRYCVFSHDEMICK

KDM5B

621

Q9UGL1
KMAECAHFHYENVEF

ARHGAP32

116

A7KAX9
DECAAKMHYCHANTV

NELL1

436

Q92832
FLNTCFHMDTCKYVH

METTL3

316

Q86U44
FHMDTCKYVHYEIDA

METTL3

321

Q86U44
HMKHFCCFECETVLG

PRICKLE2

216

Q7Z3G6
VYCFEAFDLLTSHHM

CDC16

161

Q13042
TEHICDSIMKFSECY

CYP2A7

51

P20853
FCMSNVIHHFFCDKP

OR5B17

166

Q8NGF7
DYDLCTQCYMHNKHE

MIB2

111

Q96AX9
YFCTELHCKKFFEMV

MAP3K5

636

Q99683
EVDCEKFYSFIHMTF

NLRP3

511

Q96P20
ESLCHCPFYEEAMHL

MIGA1

346

Q8NAN2
IEDYFHCKHMTSECF

TDRD7

686

Q8NHU6
CFQTKEHVCFVMEYA

PKN2

726

Q16513
FLENMEVECNYHCYH

COA7

16

Q96BR5
IFSDHHTMCYCEDGF

VWF

721

P04275
DFNHFYAMDETHHKC

PLCXD2

161

Q0VAA5
NCSDMCFHQKYRTHD

PXDN

731

Q92626
DHYSCQCHSYADMRE

WDFY4

2456

Q6ZS81
CHSDAMCTDLHFQEK

STAB1

2191

Q9NY15
CHPYDSSHKEFQCMK

ZNFX1

1306

Q9P2E3
YDEMCFHIETAHFEQ

ZUP1

41

Q96AP4
SMDRDYHVACYHCED

WTIP

371

A6NIX2
CEFMHGYFHEEATLC

RHBDF2

616

Q6PJF5
YYHATKAMTHFTDEC

TBK1

591

Q9UHD2
CDKSFHFYCRLKVHM

ZBTB40

741

Q9NUA8
DRDCTDTTHYCMFVK

ADAMTSL3

1656

P82987