Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	small GTPase binding	DVL2 DVL3 RIMS1 BRAF ANKRD27 SRGAP1	7.91e-05	321	45	6	GO:0031267
GeneOntologyMolecularFunction	protein kinase binding	DVL2 NEDD9 APC RICTOR RIMS1 MAPK8 BRAF DSCAM ITGB1BP1	1.20e-04	873	45	9	GO:0019901
GeneOntologyMolecularFunction	GTPase binding	DVL2 DVL3 RIMS1 BRAF ANKRD27 SRGAP1	1.48e-04	360	45	6	GO:0051020
GeneOntologyMolecularFunction	kinase binding	DVL2 NEDD9 APC RICTOR RIMS1 MAPK8 BRAF DSCAM ITGB1BP1	2.63e-04	969	45	9	GO:0019900
GeneOntologyMolecularFunction	GTPase regulator activity	ARHGAP25 RIMS1 HERC1 ANKRD27 SRGAP1 ITGB1BP1	9.14e-04	507	45	6	GO:0030695
GeneOntologyMolecularFunction	nucleoside-triphosphatase regulator activity	ARHGAP25 RIMS1 HERC1 ANKRD27 SRGAP1 ITGB1BP1	9.14e-04	507	45	6	GO:0060589
GeneOntologyMolecularFunction	enzyme regulator activity	APC RICTOR ARHGAP25 RIMS1 HERC1 MAPK8 CCNB3 ANKRD27 SRGAP1 ITGB1BP1	1.02e-03	1418	45	10	GO:0030234
GeneOntologyBiologicalProcess	regulation of cytoskeleton organization	DVL2 DVL3 NEDD9 APC RICTOR IQCJ-SCHIP1 LIMCH1 MAPK8 BRAF SSH1 ITGB1BP1	3.31e-08	579	45	11	GO:0051493
GeneOntologyBiologicalProcess	cell projection morphogenesis	DVL2 DVL3 APC RIMS1 NRXN3 TRAK2 MAPK8 BRAF DSCAM RPS6KA5 MUC3A ANKRD27	1.34e-07	826	45	12	GO:0048858
GeneOntologyBiologicalProcess	neuron projection morphogenesis	DVL2 DVL3 APC RIMS1 NRXN3 TRAK2 MAPK8 BRAF DSCAM RPS6KA5 ANKRD27	8.68e-07	802	45	11	GO:0048812
GeneOntologyBiologicalProcess	cell morphogenesis	DVL2 DVL3 APC RIMS1 NRXN3 TRAK2 MAPK8 BRAF SSH1 DSCAM RPS6KA5 MUC3A ANKRD27	9.85e-07	1194	45	13	GO:0000902
GeneOntologyBiologicalProcess	plasma membrane bounded cell projection morphogenesis	DVL2 DVL3 APC RIMS1 NRXN3 TRAK2 MAPK8 BRAF DSCAM RPS6KA5 ANKRD27	1.07e-06	819	45	11	GO:0120039
GeneOntologyBiologicalProcess	regulation of actin cytoskeleton organization	DVL2 DVL3 NEDD9 RICTOR LIMCH1 BRAF SSH1 ITGB1BP1	1.58e-06	384	45	8	GO:0032956
GeneOntologyBiologicalProcess	regulation of organelle organization	DVL2 DVL3 NEDD9 APC RICTOR IQCJ-SCHIP1 LIMCH1 RIMS1 MAPK8 BRAF SSH1 ANKRD27 ITGB1BP1	3.63e-06	1342	45	13	GO:0033043
GeneOntologyBiologicalProcess	positive regulation of supramolecular fiber organization	APC RICTOR LIMCH1 MAPK8 BRAF ITGB1BP1	4.08e-06	196	45	6	GO:1902905
GeneOntologyBiologicalProcess	regulation of actin filament-based process	DVL2 DVL3 NEDD9 RICTOR LIMCH1 BRAF SSH1 ITGB1BP1	4.20e-06	438	45	8	GO:0032970
GeneOntologyBiologicalProcess	positive regulation of cellular component organization	DVL2 DVL3 NEDD9 APC RICTOR LIMCH1 RIMS1 MAPK8 BRAF SSH1 DSCAM ANKRD27 ITGB1BP1	4.41e-06	1366	45	13	GO:0051130
GeneOntologyBiologicalProcess	positive regulation of cytoskeleton organization	APC RICTOR LIMCH1 MAPK8 BRAF ITGB1BP1	5.28e-06	205	45	6	GO:0051495
GeneOntologyBiologicalProcess	neuron projection development	DVL2 DVL3 APC RIMS1 NRXN3 TRAK2 HERC1 MAPK8 BRAF DSCAM RPS6KA5 ANKRD27	1.37e-05	1285	45	12	GO:0031175
GeneOntologyBiologicalProcess	hepatoblast differentiation	TBX3 HNF1B	1.39e-05	3	45	2	GO:0061017
GeneOntologyBiologicalProcess	supramolecular fiber organization	NEDD9 APC RICTOR ARHGAP25 LIMCH1 CEP126 MAPK8 BRAF SSH1 ITGB1BP1	3.20e-05	957	45	10	GO:0097435
GeneOntologyBiologicalProcess	positive regulation of phosphorylation	DVL2 DVL3 NEDD9 FGF5 RICTOR LIMCH1 BRAF DSCAM ITGB1BP1	3.94e-05	780	45	9	GO:0042327
GeneOntologyBiologicalProcess	regulation of supramolecular fiber organization	APC RICTOR LIMCH1 MAPK8 BRAF SSH1 ITGB1BP1	4.19e-05	438	45	7	GO:1902903
GeneOntologyBiologicalProcess	positive regulation of protein metabolic process	DVL2 DVL3 NEDD9 APC PRR16 FGF5 RICTOR LIMCH1 MAPK8 BRAF HECTD1 ITGB1BP1	4.78e-05	1458	45	12	GO:0051247
GeneOntologyBiologicalProcess	regulation of phosphorylation	DVL2 DVL3 NEDD9 APC FGF5 RICTOR LIMCH1 BRAF DSCAM CCNB3 ITGB1BP1	4.88e-05	1226	45	11	GO:0042325
GeneOntologyBiologicalProcess	actin cytoskeleton organization	DVL2 DVL3 NEDD9 RICTOR ARHGAP25 LIMCH1 BRAF SSH1 ITGB1BP1	4.93e-05	803	45	9	GO:0030036
GeneOntologyBiologicalProcess	neuron development	DVL2 DVL3 APC RIMS1 NRXN3 TRAK2 HERC1 MAPK8 BRAF DSCAM RPS6KA5 ANKRD27	4.95e-05	1463	45	12	GO:0048666
GeneOntologyBiologicalProcess	tube formation	DVL2 DVL3 HNF1B HECTD1 ITGB1BP1	5.29e-05	187	45	5	GO:0035148
GeneOntologyBiologicalProcess	regulation of GTPase activity	DVL2 DVL3 NEDD9 RICTOR ARHGAP25 ITGB1BP1	8.38e-05	335	45	6	GO:0043087
GeneOntologyBiologicalProcess	positive regulation of cell projection organization	DVL2 DVL3 NEDD9 APC BRAF DSCAM ANKRD27	8.94e-05	494	45	7	GO:0031346
GeneOntologyBiologicalProcess	positive regulation of phosphate metabolic process	DVL2 DVL3 NEDD9 FGF5 RICTOR LIMCH1 BRAF DSCAM ITGB1BP1	9.89e-05	879	45	9	GO:0045937
GeneOntologyBiologicalProcess	positive regulation of phosphorus metabolic process	DVL2 DVL3 NEDD9 FGF5 RICTOR LIMCH1 BRAF DSCAM ITGB1BP1	9.89e-05	879	45	9	GO:0010562
GeneOntologyBiologicalProcess	actin filament organization	NEDD9 RICTOR ARHGAP25 LIMCH1 BRAF SSH1 ITGB1BP1	1.08e-04	509	45	7	GO:0007015
GeneOntologyBiologicalProcess	positive regulation of neuron projection arborization	DVL2 DVL3	1.29e-04	8	45	2	GO:0150012
GeneOntologyBiologicalProcess	actin filament-based process	DVL2 DVL3 NEDD9 RICTOR ARHGAP25 LIMCH1 BRAF SSH1 ITGB1BP1	1.31e-04	912	45	9	GO:0030029
GeneOntologyBiologicalProcess	regulation of protein phosphorylation	DVL2 DVL3 NEDD9 APC FGF5 RICTOR LIMCH1 BRAF CCNB3 ITGB1BP1	1.32e-04	1133	45	10	GO:0001932
GeneOntologyBiologicalProcess	positive regulation of protein phosphorylation	DVL2 DVL3 NEDD9 FGF5 RICTOR LIMCH1 BRAF ITGB1BP1	1.51e-04	724	45	8	GO:0001934
GeneOntologyBiologicalProcess	positive regulation of protein modification process	DVL2 DVL3 NEDD9 FGF5 RICTOR LIMCH1 MAPK8 BRAF ITGB1BP1	1.61e-04	937	45	9	GO:0031401
GeneOntologyBiologicalProcess	stem cell population maintenance	APC TBX3 HNF1B MAPK8 BRAF	1.61e-04	237	45	5	GO:0019827
GeneOntologyBiologicalProcess	maintenance of cell number	APC TBX3 HNF1B MAPK8 BRAF	1.78e-04	242	45	5	GO:0098727
GeneOntologyBiologicalProcess	regulation of phosphate metabolic process	DVL2 DVL3 NEDD9 APC FGF5 RICTOR LIMCH1 BRAF DSCAM CCNB3 ITGB1BP1	1.83e-04	1421	45	11	GO:0019220
GeneOntologyBiologicalProcess	regulation of phosphorus metabolic process	DVL2 DVL3 NEDD9 APC FGF5 RICTOR LIMCH1 BRAF DSCAM CCNB3 ITGB1BP1	1.85e-04	1423	45	11	GO:0051174
GeneOntologyBiologicalProcess	cell morphogenesis involved in neuron differentiation	APC NRXN3 TRAK2 MAPK8 BRAF DSCAM RPS6KA5 ANKRD27	1.89e-04	748	45	8	GO:0048667
GeneOntologyBiologicalProcess	cell junction organization	NEDD9 APC TANC1 LIMCH1 NRXN3 SSH1 DSCAM RPS6KA5 ITGB1BP1	2.15e-04	974	45	9	GO:0034330
GeneOntologyBiologicalProcess	positive regulation of organelle organization	APC RICTOR LIMCH1 RIMS1 MAPK8 BRAF ITGB1BP1	2.26e-04	574	45	7	GO:0010638
GeneOntologyBiologicalProcess	positive regulation of cellular component biogenesis	APC RICTOR LIMCH1 RIMS1 MAPK8 BRAF ITGB1BP1	2.46e-04	582	45	7	GO:0044089
GeneOntologyBiologicalProcess	regulation of fibroblast migration	APC BRAF ITGB1BP1	2.48e-04	56	45	3	GO:0010762
GeneOntologyBiologicalProcess	regulation of protein modification process	DVL2 DVL3 NEDD9 APC FGF5 RICTOR LIMCH1 MAPK8 BRAF CCNB3 ITGB1BP1	2.74e-04	1488	45	11	GO:0031399
GeneOntologyBiologicalProcess	positive regulation of stress fiber assembly	LIMCH1 BRAF ITGB1BP1	2.90e-04	59	45	3	GO:0051496
GeneOntologyBiologicalProcess	embryonic epithelial tube formation	DVL2 DVL3 HNF1B HECTD1	3.96e-04	159	45	4	GO:0001838
GeneOntologyBiologicalProcess	regulation of substrate adhesion-dependent cell spreading	NEDD9 BRAF ITGB1BP1	4.03e-04	66	45	3	GO:1900024
GeneOntologyBiologicalProcess	negative regulation of fibroblast migration	BRAF ITGB1BP1	4.17e-04	14	45	2	GO:0010764
GeneOntologyBiologicalProcess	positive regulation of actin filament bundle assembly	LIMCH1 BRAF ITGB1BP1	4.60e-04	69	45	3	GO:0032233
GeneOntologyBiologicalProcess	regulation of locomotion	NEDD9 APC FGF5 LIMCH1 MAPK8 BRAF SSH1 DSCAM SRGAP1 ITGB1BP1	4.71e-04	1327	45	10	GO:0040012
GeneOntologyBiologicalProcess	regulation of actin filament organization	RICTOR LIMCH1 BRAF SSH1 ITGB1BP1	4.78e-04	300	45	5	GO:0110053
GeneOntologyBiologicalProcess	regulation of establishment of planar polarity involved in neural tube closure	DVL2 DVL3	4.80e-04	15	45	2	GO:0090178
GeneOntologyBiologicalProcess	regulation of neuron projection arborization	DVL2 DVL3	4.80e-04	15	45	2	GO:0150011
GeneOntologyBiologicalProcess	regulation of cell projection organization	DVL2 DVL3 NEDD9 APC TRAK2 BRAF DSCAM ANKRD27	4.95e-04	863	45	8	GO:0031344
GeneOntologyBiologicalProcess	epithelial tube formation	DVL2 DVL3 HNF1B HECTD1	5.45e-04	173	45	4	GO:0072175
GeneOntologyBiologicalProcess	establishment of planar polarity involved in neural tube closure	DVL2 DVL3	5.48e-04	16	45	2	GO:0090177
GeneOntologyBiologicalProcess	regionalization	DVL2 APC KMT2A TBX3 HNF1B MAPK8	5.68e-04	478	45	6	GO:0003002
GeneOntologyBiologicalProcess	postsynapse organization	NEDD9 TANC1 NRXN3 SSH1 RPS6KA5	5.79e-04	313	45	5	GO:0099173
GeneOntologyBiologicalProcess	fibroblast migration	APC BRAF ITGB1BP1	6.34e-04	77	45	3	GO:0010761
GeneOntologyBiologicalProcess	regulation of protein-containing complex assembly	APC RICTOR RIMS1 MAPK8 SSH1 ANKRD27	6.40e-04	489	45	6	GO:0043254
GeneOntologyBiologicalProcess	visual learning	KMT2A TANC1 BRAF	6.58e-04	78	45	3	GO:0008542
GeneOntologyBiologicalProcess	establishment of planar polarity of embryonic epithelium	DVL2 DVL3	6.96e-04	18	45	2	GO:0042249
GeneOntologyBiologicalProcess	cell division	NEK4 NEDD9 APC FGF5 STAG1 CCNB3 ITGB1BP1	7.24e-04	697	45	7	GO:0051301
GeneOntologyBiologicalProcess	morphogenesis of embryonic epithelium	DVL2 DVL3 HNF1B HECTD1	7.74e-04	190	45	4	GO:0016331
GeneOntologyBiologicalProcess	regulation of establishment of planar polarity	DVL2 DVL3	7.77e-04	19	45	2	GO:0090175
GeneOntologyBiologicalProcess	actin filament bundle assembly	NEDD9 LIMCH1 BRAF ITGB1BP1	7.89e-04	191	45	4	GO:0051017
GeneOntologyBiologicalProcess	actin filament bundle organization	NEDD9 LIMCH1 BRAF ITGB1BP1	8.52e-04	195	45	4	GO:0061572
GeneOntologyBiologicalProcess	visual behavior	KMT2A TANC1 BRAF	8.75e-04	86	45	3	GO:0007632
GeneOntologyBiologicalProcess	dendrite morphogenesis	TRAK2 MAPK8 DSCAM ANKRD27	9.02e-04	198	45	4	GO:0048813
GeneOntologyBiologicalProcess	regulation of cellular component biogenesis	APC RICTOR LIMCH1 RIMS1 MAPK8 BRAF SSH1 ANKRD27 ITGB1BP1	9.19e-04	1189	45	9	GO:0044087
GeneOntologyBiologicalProcess	pattern specification process	DVL2 APC KMT2A TBX3 HNF1B MAPK8	9.36e-04	526	45	6	GO:0007389
GeneOntologyBiologicalProcess	regulation of cell migration	NEDD9 APC FGF5 LIMCH1 MAPK8 BRAF SSH1 SRGAP1 ITGB1BP1	1.05e-03	1211	45	9	GO:0030334
GeneOntologyBiologicalProcess	anatomical structure formation involved in morphogenesis	DVL2 DVL3 TBX3 HNF1B TANC1 NRXN3 HERC1 DSCAM HECTD1 ITGB1BP1	1.12e-03	1483	45	10	GO:0048646
GeneOntologyBiologicalProcess	outflow tract morphogenesis	DVL2 DVL3 TBX3	1.13e-03	94	45	3	GO:0003151
GeneOntologyBiologicalProcess	learning	KMT2A TANC1 NRXN3 BRAF	1.16e-03	212	45	4	GO:0007612
GeneOntologyBiologicalProcess	learning or memory	NEDD9 KMT2A TANC1 NRXN3 BRAF	1.27e-03	373	45	5	GO:0007611
GeneOntologyBiologicalProcess	embryonic organ development	DVL2 DVL3 KMT2A TBX3 HNF1B HECTD1	1.30e-03	561	45	6	GO:0048568
GeneOntologyBiologicalProcess	axonogenesis	APC NRXN3 TRAK2 BRAF DSCAM RPS6KA5	1.36e-03	566	45	6	GO:0007409
GeneOntologyBiologicalProcess	response to light stimulus	KMT2A TANC1 MAPK8 BRAF REV1	1.41e-03	382	45	5	GO:0009416
GeneOntologyBiologicalProcess	positive regulation of protein polymerization	APC RICTOR MAPK8	1.43e-03	102	45	3	GO:0032273
GeneOntologyBiologicalProcess	positive regulation of protein-containing complex assembly	APC RICTOR RIMS1 MAPK8	1.49e-03	227	45	4	GO:0031334
GeneOntologyBiologicalProcess	positive regulation of cell division	APC FGF5 ITGB1BP1	1.52e-03	104	45	3	GO:0051781
GeneOntologyBiologicalProcess	regulation of cell motility	NEDD9 APC FGF5 LIMCH1 MAPK8 BRAF SSH1 SRGAP1 ITGB1BP1	1.54e-03	1280	45	9	GO:2000145
GeneOntologyBiologicalProcess	localization within membrane	PACS1 NRXN3 BRAF SSH1 HECTD1 ANKRD27 ITGB1BP1	1.59e-03	798	45	7	GO:0051668
GeneOntologyBiologicalProcess	regulation of protein polymerization	APC RICTOR MAPK8 SSH1	1.59e-03	231	45	4	GO:0032271
GeneOntologyBiologicalProcess	regulation of stress fiber assembly	LIMCH1 BRAF ITGB1BP1	1.64e-03	107	45	3	GO:0051492
GeneOntologyBiologicalProcess	somatic stem cell population maintenance	APC HNF1B BRAF	1.69e-03	108	45	3	GO:0035019
GeneOntologyBiologicalProcess	dense core granule localization	RIMS1 MAPK8	1.70e-03	28	45	2	GO:0032253
GeneOntologyBiologicalProcess	substrate adhesion-dependent cell spreading	NEDD9 BRAF ITGB1BP1	1.73e-03	109	45	3	GO:0034446
GeneOntologyBiologicalProcess	regulation of animal organ morphogenesis	DVL2 DVL3 APC	1.78e-03	110	45	3	GO:2000027
GeneOntologyBiologicalProcess	cochlea morphogenesis	DVL2 DVL3	1.82e-03	29	45	2	GO:0090103
GeneOntologyBiologicalProcess	epithelial cell proliferation	APC BNC1 MUC16 RICTOR HNF1B ITGB1BP1	1.88e-03	603	45	6	GO:0050673
GeneOntologyBiologicalProcess	neural tube closure	DVL2 DVL3 HECTD1	1.92e-03	113	45	3	GO:0001843
GeneOntologyBiologicalProcess	positive regulation of GTPase activity	DVL2 DVL3 NEDD9 ARHGAP25	1.95e-03	244	45	4	GO:0043547
GeneOntologyBiologicalProcess	dendritic spine maintenance	NEDD9 TANC1	1.95e-03	30	45	2	GO:0097062
GeneOntologyBiologicalProcess	tube closure	DVL2 DVL3 HECTD1	1.97e-03	114	45	3	GO:0060606
GeneOntologyBiologicalProcess	anterior/posterior pattern specification	APC KMT2A TBX3 HNF1B	2.03e-03	247	45	4	GO:0009952
GeneOntologyBiologicalProcess	positive regulation of cell development	NEDD9 BNC1 MAPK8 BRAF DSCAM ANKRD27	2.06e-03	614	45	6	GO:0010720
GeneOntologyBiologicalProcess	negative regulation of cell migration	NEDD9 LIMCH1 BRAF SRGAP1 ITGB1BP1	2.12e-03	419	45	5	GO:0030336
GeneOntologyBiologicalProcess	regulation of anatomical structure size	PRR16 RICTOR HNF1B SSH1 DSCAM ITGB1BP1	2.13e-03	618	45	6	GO:0090066
GeneOntologyBiologicalProcess	epithelial tube morphogenesis	DVL2 DVL3 TBX3 HNF1B HECTD1	2.16e-03	421	45	5	GO:0060562
HumanPheno	Long eyelashes	DVL3 KMT2A FGF5 PACS1 STAG1	2.36e-05	129	15	5	HP:0000527
Domain	Dsh_C	DVL2 DVL3	1.78e-05	3	46	2	PF12316
Domain	Dishevelled_C-dom	DVL2 DVL3	1.78e-05	3	46	2	IPR024580
Domain	Dsh/Dvl-rel	DVL2 DVL3	3.55e-05	4	46	2	IPR015506
Domain	Dishevelled_fam	DVL2 DVL3	3.55e-05	4	46	2	IPR008339
Domain	Dishevelled	DVL2 DVL3	3.55e-05	4	46	2	PF02377
Domain	Dishevelled_protein_dom	DVL2 DVL3	3.55e-05	4	46	2	IPR003351
Domain	DIX	DVL2 DVL3	1.24e-04	7	46	2	PF00778
Domain	DIX	DVL2 DVL3	1.24e-04	7	46	2	IPR001158
Domain	DIX	DVL2 DVL3	1.24e-04	7	46	2	PS50841
Domain	DAX	DVL2 DVL3	1.24e-04	7	46	2	SM00021
Domain	SEA	MUC16 MUC3A	5.30e-04	14	46	2	SM00200
Domain	DEP	DVL2 DVL3	1.33e-03	22	46	2	PF00610
Domain	DEP	DVL2 DVL3	1.33e-03	22	46	2	PS50186
Domain	DEP	DVL2 DVL3	1.33e-03	22	46	2	SM00049
Domain	DEP_dom	DVL2 DVL3	1.45e-03	23	46	2	IPR000591
Domain	SEA	MUC16 MUC3A	1.45e-03	23	46	2	PS50024
Domain	SEA_dom	MUC16 MUC3A	1.45e-03	23	46	2	IPR000082
Domain	HECT	HERC1 HECTD1	2.00e-03	27	46	2	PF00632
Domain	HECTc	HERC1 HECTD1	2.00e-03	27	46	2	SM00119
Domain	HECT_dom	HERC1 HECTD1	2.00e-03	27	46	2	IPR000569
Domain	HECT	HERC1 HECTD1	2.00e-03	27	46	2	PS50237
Domain	ANK_REPEAT	MUC16 TANC1 HECTD1 ANKRD27	3.43e-03	253	46	4	PS50088
Domain	ANK_REP_REGION	MUC16 TANC1 HECTD1 ANKRD27	3.48e-03	254	46	4	PS50297
Domain	ARM-like	APC RICTOR STAG1 HECTD1	4.33e-03	270	46	4	IPR011989
Domain	BROMODOMAIN_2	KMT2A BAZ2B	4.58e-03	41	46	2	PS50014
Domain	BROMO	KMT2A BAZ2B	4.80e-03	42	46	2	SM00297
Domain	Bromodomain	KMT2A BAZ2B	4.80e-03	42	46	2	IPR001487
Domain	-	KMT2A BAZ2B	4.80e-03	42	46	2	1.20.920.10
Pathway	REACTOME_KILLING_MECHANISMS	DVL2 DVL3 MAPK8	2.53e-06	12	33	3	M29844
Pathway	WP_WNT_SIGNALING_IN_KIDNEY_DISEASE	DVL2 DVL3 APC MAPK8	3.16e-06	44	33	4	MM15878
Pathway	WP_WNT_SIGNALING_WP363	DVL2 DVL3 APC MAPK8	5.75e-06	51	33	4	M39721
Pathway	REACTOME_DEFECTIVE_GALNT3_CAUSES_HFTC	MUC16 MUC3A MUC6	6.41e-06	16	33	3	M27410
Pathway	WP_ESC_PLURIPOTENCY_PATHWAYS	DVL2 DVL3 APC FGF5 BRAF	6.83e-06	116	33	5	MM15863
Pathway	WP_EMBRYONIC_STEM_CELL_PLURIPOTENCY_PATHWAYS	DVL2 DVL3 APC FGF5 BRAF	7.12e-06	117	33	5	M39530
Pathway	REACTOME_DEFECTIVE_C1GALT1C1_CAUSES_TNPS	MUC16 MUC3A MUC6	7.77e-06	17	33	3	M27412
Pathway	PID_BETA_CATENIN_DEG_PATHWAY	DVL2 DVL3 APC	9.31e-06	18	33	3	M31
Pathway	PID_WNT_CANONICAL_PATHWAY	DVL2 DVL3 APC	1.30e-05	20	33	3	M90
Pathway	REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS	MUC16 MUC3A MUC6	2.00e-05	23	33	3	M556
Pathway	WP_BREAST_CANCER_PATHWAY	DVL2 DVL3 APC FGF5 BRAF	2.70e-05	154	33	5	M39739
Pathway	REACTOME_DECTIN_2_FAMILY	MUC16 MUC3A MUC6	2.93e-05	26	33	3	M27483
Pathway	REACTOME_DISASSEMBLY_OF_THE_DESTRUCTION_COMPLEX_AND_RECRUITMENT_OF_AXIN_TO_THE_MEMBRANE	DVL2 DVL3 APC	5.02e-05	31	33	3	M27400
Pathway	REACTOME_DISASSEMBLY_OF_THE_DESTRUCTION_COMPLEX_AND_RECRUITMENT_OF_AXIN_TO_THE_MEMBRANE	DVL2 DVL3 APC	5.02e-05	31	33	3	MM15154
Pathway	REACTOME_NEGATIVE_REGULATION_OF_TCF_DEPENDENT_SIGNALING_BY_DVL_INTERACTING_PROTEINS	DVL2 DVL3	5.29e-05	5	33	2	M27447
Pathway	PID_WNT_NONCANONICAL_PATHWAY	DVL2 DVL3 MAPK8	5.53e-05	32	33	3	M23
Pathway	WP_WNT_SIGNALING_IN_KIDNEY_DISEASE	DVL2 DVL3 MAPK8	7.92e-05	36	33	3	M39699
Pathway	KEGG_MEDICUS_VARIANT_FZD7_OVEREXPRESSION_TO_WNT_SIGNALING_PATHWAY	DVL2 DVL3 APC	8.60e-05	37	33	3	M47411
Pathway	WP_WNT_SIGNALING_PATHWAY_AND_PLURIPOTENCY	DVL2 DVL3 APC HNF1B	8.66e-05	101	33	4	MM15829
Pathway	KEGG_PATHWAYS_IN_CANCER	DVL2 DVL3 APC FGF5 MAPK8 BRAF	9.39e-05	325	33	6	M12868
Pathway	PID_ERBB1_DOWNSTREAM_PATHWAY	RICTOR MAPK8 BRAF RPS6KA5	1.01e-04	105	33	4	M164
Pathway	WP_WNT_SIGNALING_PATHWAY	DVL2 DVL3 APC MAPK8	1.21e-04	110	33	4	MM15977
Pathway	WP_DNA_DAMAGE_RESPONSE_ONLY_ATM_DEPENDENT	DVL2 DVL3 APC MAPK8	1.21e-04	110	33	4	M39492
Pathway	WP_WNT_SIGNALING_WP428	DVL2 DVL3 APC MAPK8	1.34e-04	113	33	4	M39669
Pathway	REACTOME_WNT_MEDIATED_ACTIVATION_OF_DVL	DVL2 DVL3	1.47e-04	8	33	2	M27100
Pathway	KEGG_MEDICUS_VARIANT_LRP6_OVEREXPRESSION_TO_WNT_SIGNALING_PATHWAY	DVL2 DVL3 APC	1.55e-04	45	33	3	M47412
Pathway	KEGG_MEDICUS_REFERENCE_WNT_SIGNALING_PATHWAY	DVL2 DVL3 APC	1.66e-04	46	33	3	M47409
Pathway	REACTOME_WNT_MEDIATED_ACTIVATION_OF_DVL	DVL2 DVL3	1.89e-04	9	33	2	MM14792
Pathway	KEGG_MEDICUS_VARIANT_HRAS_OVEREXPRESSION_TO_ERK_SIGNALING_PATHWAY	BRAF RPS6KA5	2.36e-04	10	33	2	M47420
Pathway	KEGG_BASAL_CELL_CARCINOMA	DVL2 DVL3 APC	2.82e-04	55	33	3	M17807
Pathway	REACTOME_C_TYPE_LECTIN_RECEPTORS_CLRS	MUC16 RPS6KA5 MUC3A MUC6	3.05e-04	140	33	4	M27484
Pathway	WP_ALZHEIMERS_DISEASE	DVL2 DVL3 APC MAPK8 BRAF	3.25e-04	261	33	5	M42565
Pathway	WP_WNT_SIGNALING	DVL2 DVL3 APC	3.83e-04	61	33	3	MM15893
Pathway	WP_REGULATION_OF_ACTIN_CYTOSKELETON	APC FGF5 BRAF SSH1	3.96e-04	150	33	4	M39520
Pathway	KEGG_COLORECTAL_CANCER	APC MAPK8 BRAF	4.02e-04	62	33	3	M14631
Pathway	REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS	MUC16 MUC3A MUC6	4.02e-04	62	33	3	M546
Pathway	KEGG_WNT_SIGNALING_PATHWAY	DVL2 DVL3 APC MAPK8	4.06e-04	151	33	4	M19428
Pathway	WP_REGULATION_OF_ACTIN_CYTOSKELETON	APC FGF5 BRAF SSH1	4.17e-04	152	33	4	MM15834
Pathway	WP_REGULATION_OF_SISTER_CHROMATID_SEPARATION_AT_THE_METAPHASEANAPHASE_TRANSITION	APC STAG1	4.75e-04	14	33	2	M39772
Pathway	WP_PLEURAL_MESOTHELIOMA	DVL2 DVL3 APC FGF5 MAPK8 RPS6KA5	4.78e-04	439	33	6	M42563
Pathway	REACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS	MUC16 MUC3A MUC6	5.28e-04	68	33	3	M27303
Pathway	WP_EGFEGFR_SIGNALING	RICTOR MAPK8 BRAF RPS6KA5	5.30e-04	162	33	4	M39334
Pathway	PID_CDC42_PATHWAY	APC MAPK8 BRAF	5.75e-04	70	33	3	M81
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_FGFR3_TO_RAS_ERK_SIGNALING_PATHWAY	BRAF RPS6KA5	6.25e-04	16	33	2	M47373
Pathway	KEGG_MEDICUS_REFERENCE_WNT5A_ROR_SIGNALING_PATHWAY	DVL2 DVL3	6.25e-04	16	33	2	M47823
Pathway	WP_CHROMOSOMAL_AND_MICROSATELLITE_INSTABILITY_IN_COLORECTAL_CANCER	APC MAPK8 BRAF	6.50e-04	73	33	3	M39758
Pathway	WP_REGULATION_OF_WNT_BCATENIN_SIGNALING_BY_SMALL_MOLECULE_COMPOUNDS	DVL2 APC	7.07e-04	17	33	2	M39525
Pathway	WP_SEROTONIN_RECEPTOR_467_AND_NR3C_SIGNALING	BRAF RPS6KA5	8.86e-04	19	33	2	M39358
Pathway	WP_ALZHEIMERS_DISEASE_AND_MIRNA_EFFECTS	DVL2 DVL3 APC MAPK8 BRAF	8.94e-04	326	33	5	M39379
Pathway	KEGG_PROGESTERONE_MEDIATED_OOCYTE_MATURATION	MAPK8 BRAF CCNB3	1.01e-03	85	33	3	M3578
Pathway	WP_POLYCYSTIC_KIDNEY_DISEASE_PATHWAY	DVL2 DVL3 BRAF	1.01e-03	85	33	3	M48315
Pathway	WP_CANCER_PATHWAYS	DVL2 DVL3 APC MAPK8 BRAF RPS6KA5	1.02e-03	507	33	6	M48302
Pathway	REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS	MUC16 MUC6	1.09e-03	21	33	2	MM15706
Pathway	WP_NCRNAS_INVOLVED_IN_WNT_SIGNALING_IN_HEPATOCELLULAR_CARCINOMA	DVL2 DVL3 APC	1.16e-03	89	33	3	M39563
Pathway	KEGG_REGULATION_OF_ACTIN_CYTOSKELETON	APC FGF5 BRAF SSH1	1.47e-03	213	33	4	M18306
Pathway	WP_LNCRNA_IN_CANONICAL_WNT_SIGNALING_AND_COLORECTAL_CANCER	DVL2 DVL3 APC	1.53e-03	98	33	3	M39731
Pathway	WP_WNT_SIGNALING_AND_PLURIPOTENCY	DVL2 DVL3 APC	1.67e-03	101	33	3	M39387
Pathway	WP_HIPPOCAMPAL_SYNAPTOGENESIS_AND_NEUROGENESIS	NRXN3 RPS6KA5	1.80e-03	27	33	2	M45550
Pathway	REACTOME_MAPK_TARGETS_NUCLEAR_EVENTS_MEDIATED_BY_MAP_KINASES	MAPK8 RPS6KA5	1.93e-03	28	33	2	MM15132
Pathway	REACTOME_NEGATIVE_REGULATION_OF_FGFR3_SIGNALING	FGF5 BRAF	2.07e-03	29	33	2	M27528
Pathway	REACTOME_NEGATIVE_REGULATION_OF_FGFR3_SIGNALING	FGF5 BRAF	2.07e-03	29	33	2	MM15253
Pathway	REACTOME_O_LINKED_GLYCOSYLATION	MUC16 MUC3A MUC6	2.18e-03	111	33	3	M27416
Pathway	WP_HDAC6_INTERACTIONS_IN_THE_CENTRAL_NERVOUS_SYSTEM	NEDD9 APC MAPK8	2.30e-03	113	33	3	M48336
Pathway	REACTOME_MAPK_TARGETS_NUCLEAR_EVENTS_MEDIATED_BY_MAP_KINASES	MAPK8 RPS6KA5	2.37e-03	31	33	2	M15195
Pathway	WP_MAPK_SIGNALING	FGF5 MAPK8 BRAF RPS6KA5	2.49e-03	246	33	4	M39597
Pathway	WP_EFFECT_OF_OMEGA3_PUFA_ON_HUNTINGTONS_DISEASE_PATHWAYS	RICTOR MAPK8 RPS6KA5	2.66e-03	119	33	3	M48309
Pathway	REACTOME_NEGATIVE_REGULATION_OF_FGFR1_SIGNALING	FGF5 BRAF	2.68e-03	33	33	2	M27526
Pathway	REACTOME_NEGATIVE_REGULATION_OF_FGFR2_SIGNALING	FGF5 BRAF	2.68e-03	33	33	2	MM15252
Pathway	REACTOME_NEGATIVE_REGULATION_OF_FGFR2_SIGNALING	FGF5 BRAF	2.84e-03	34	33	2	M27527
Pathway	PID_MAPK_TRK_PATHWAY	BRAF RPS6KA5	2.84e-03	34	33	2	M270
Pathway	KEGG_MEDICUS_REFERENCE_FGF_FGFR_RAS_ERK_SIGNALING_PATHWAY	FGF5 BRAF	3.01e-03	35	33	2	M47379
Pathway	KEGG_NEUROTROPHIN_SIGNALING_PATHWAY	MAPK8 BRAF RPS6KA5	3.13e-03	126	33	3	M16763
Pathway	KEGG_MAPK_SIGNALING_PATHWAY	FGF5 MAPK8 BRAF RPS6KA5	3.34e-03	267	33	4	M10792
Pathway	WP_SEROTONIN_HTR1_GROUP_AND_FOS_PATHWAY	BRAF RPS6KA5	3.36e-03	37	33	2	M42558
Pathway	WP_ANGIOPOIETINLIKE_PROTEIN_8_REGULATORY_PATHWAY	RICTOR MAPK8 RPS6KA5	3.57e-03	132	33	3	M39338
Pathway	REACTOME_SIGNALING_BY_FGFR3	FGF5 BRAF	3.73e-03	39	33	2	MM15257
Pathway	REACTOME_SIGNALING_BY_FGFR3	FGF5 BRAF	3.92e-03	40	33	2	M27532
Pathway	WP_BLADDER_CANCER	BRAF RPS6KA5	3.92e-03	40	33	2	M39523
Pathway	REACTOME_DISEASES_OF_SIGNAL_TRANSDUCTION_BY_GROWTH_FACTOR_RECEPTORS_AND_SECOND_MESSENGERS	APC FGF5 RICTOR MAPK8 BRAF	4.19e-03	464	33	5	M27547
Pathway	KEGG_BLADDER_CANCER	BRAF RPS6KA5	4.32e-03	42	33	2	M19096
Pathway	WP_ENDODERM_DIFFERENTIATION	APC HNF1B ZFHX4	4.46e-03	143	33	3	M39591
Pathway	REACTOME_DISEASES_OF_GLYCOSYLATION	MUC16 MUC3A MUC6	4.46e-03	143	33	3	M27275
Pathway	WP_BRAINDERIVED_NEUROTROPHIC_FACTOR_BDNF_SIGNALING	APC MAPK8 RPS6KA5	4.55e-03	144	33	3	M39691
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	NEK4 APC KMT2A RICTOR TANC1 LIMCH1 EDC4 BRAF HECTD1 ANKRD27 SRGAP1	1.55e-08	861	47	11	36931259
Pubmed	RNF43 truncations trap CK1 to drive niche-independent self-renewal in cancer.	DVL2 DVL3 APC	1.93e-07	9	47	3	32965059
Pubmed	Wnt signaling is required for organization of the lens fiber cell cytoskeleton and development of lens three-dimensional architecture.	DVL2 DVL3 MAPK8	5.05e-07	12	47	3	18824165
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	KMT2A PACS1 RICTOR LIMCH1 RIMS1 MAPK8 BRAF SSH1 RPS6KA5	8.17e-07	774	47	9	15302935
Pubmed	Lower serum CA125 level, negative vascular invasion, and wild BRAF were strongly associated with better 2-year disease-free survival in patients with stage III colorectal cancer who received adjuvant chemotherapy.	MUC16 BRAF	1.79e-06	2	47	2	29562502
Pubmed	Selective inhibition of proliferation in colorectal carcinoma cell lines expressing mutant APC or activated B-Raf.	APC BRAF	1.79e-06	2	47	2	19378335
Pubmed	Proteomic identification of overexpressed adenomatous polyposis coli and cyclin B3 during endoderm differentiation from human embryonic stem cells.	APC CCNB3	1.79e-06	2	47	2	21404461
Pubmed	Genetic analysis of disheveled 2 and disheveled 3 in human neural tube defects.	DVL2 DVL3	1.79e-06	2	47	2	22892949
Pubmed	Protein kinase Msk1 physically and functionally interacts with the KMT2A/MLL1 methyltransferase complex and contributes to the regulation of multiple target genes.	KMT2A RPS6KA5	1.79e-06	2	47	2	27895715
Pubmed	Dvl2 promotes intestinal length and neoplasia in the ApcMin mouse model for colorectal cancer.	DVL2 APC	1.79e-06	2	47	2	20663899
Pubmed	RICTOR/mTORC2 downregulation in BRAFV600E melanoma cells promotes resistance to BRAF/MEK inhibition.	RICTOR BRAF	1.79e-06	2	47	2	38755661
Pubmed	Planar polarization of node cells determines the rotational axis of node cilia.	DVL2 DVL3	1.79e-06	2	47	2	20098415
Pubmed	Disheveled proteins promote cell growth and tumorigenicity in ALK-positive anaplastic large cell lymphoma.	DVL2 DVL3	1.79e-06	2	47	2	23022960
Pubmed	HEF1, a novel target of Wnt signaling, promotes colonic cell migration and cancer progression.	NEDD9 APC	1.79e-06	2	47	2	21317929
Pubmed	Mucin gene expression in human laryngeal epithelia: effect of laryngopharyngeal reflux.	MUC16 MUC3A MUC6	1.86e-06	18	47	3	18834073
Pubmed	Posterior malformations in Dact1 mutant mice arise through misregulated Vangl2 at the primitive streak.	DVL2 DVL3 MAPK8	1.86e-06	18	47	3	19701191
Pubmed	PIK3CA mutation is a favorable prognostic factor in esophageal cancer: molecular profile by next-generation sequencing using surgically resected formalin-fixed, paraffin-embedded tissue.	APC BRAF	5.36e-06	3	47	2	30115035
Pubmed	Differential mediation of the Wnt canonical pathway by mammalian Dishevelleds-1, -2, and -3.	DVL2 DVL3	5.36e-06	3	47	2	18093802
Pubmed	DVL mutations identified from human neural tube defects and Dandy-Walker malformation obstruct the Wnt signaling pathway.	DVL2 DVL3	5.36e-06	3	47	2	32900645
Pubmed	Essential role of the Dishevelled DEP domain in a Wnt-dependent human-cell-based complementation assay.	DVL2 DVL3	5.36e-06	3	47	2	27744318
Pubmed	Binding of APC and dishevelled mediates Wnt5a-regulated focal adhesion dynamics in migrating cells.	DVL2 APC	5.36e-06	3	47	2	20224554
Pubmed	BRAFV600E drives dedifferentiation in small intestinal and colonic organoids and cooperates with mutant p53 and Apc loss in transformation.	APC BRAF	5.36e-06	3	47	2	32792685
Pubmed	IQCJ-SCHIP1, a novel fusion transcript encoding a calmodulin-binding IQ motif protein.	IQCJ-SCHIP1 IQCJ	5.36e-06	3	47	2	17045569
Pubmed	Dishevelled stability is positively regulated by PKCζ-mediated phosphorylation induced by Wnt agonists.	DVL2 DVL3	5.36e-06	3	47	2	28366812
Pubmed	Increased cancer predisposition in family members of colorectal cancer patients harboring the p.V600E BRAF mutation: a population-based study.	APC BRAF	5.36e-06	3	47	2	20570909
Pubmed	Genetic Polymorphisms in APC, DVL2, and AXIN1 Are Associated with Susceptibility, Advanced TNM Stage or Tumor Location in Colorectal Cancer.	DVL2 APC	5.36e-06	3	47	2	31723073
Pubmed	Thyroid Carcinomas That Occur in Familial Adenomatous Polyposis Patients Recurrently Harbor Somatic Variants in APC, BRAF, and KTM2D.	APC BRAF	5.36e-06	3	47	2	32024448
Pubmed	Dishevelled proteins are significantly upregulated in chronic lymphocytic leukaemia.	DVL2 DVL3	5.36e-06	3	47	2	27086035
Pubmed	Carcinogen-specific mutations in preferred Ras-Raf pathway oncogenes directed by strand bias.	APC BRAF	5.36e-06	3	47	2	27207659
Pubmed	Dishevelled-3 C-terminal His single amino acid repeats are obligate for Wnt5a activation of non-canonical signaling.	DVL2 DVL3	5.36e-06	3	47	2	21092292
Pubmed	APC binds the Miro/Milton motor complex to stimulate transport of mitochondria to the plasma membrane.	APC TRAK2	5.36e-06	3	47	2	26658612
Pubmed	Oncogenic B-RAF(V600E) signaling induces the T-Box3 transcriptional repressor to repress E-cadherin and enhance melanoma cell invasion.	TBX3 BRAF	5.36e-06	3	47	2	23190890
Pubmed	Genomic organization of mouse Dishevelled genes.	DVL2 DVL3	5.36e-06	3	47	2	8973355
Pubmed	Dishevelled family proteins are expressed in non-small cell lung cancer and function differentially on tumor progression.	DVL2 DVL3	5.36e-06	3	47	2	18692936
Pubmed	Activation of the non-canonical Dvl-Rac1-JNK pathway by Frizzled homologue 10 in human synovial sarcoma.	DVL2 DVL3	5.36e-06	3	47	2	19137009
Pubmed	Prevalence of mutations in APC, CTNNB1, and BRAF in Tunisian patients with sporadic colorectal cancer.	APC BRAF	5.36e-06	3	47	2	18992635
Pubmed	Dishevelled proteins are associated with olfactory sensory neuron presynaptic terminals.	DVL2 DVL3	5.36e-06	3	47	2	23437169
Pubmed	A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.	DVL2 DVL3 NEK4 ZC3H7A RICTOR LIMCH1 TRAK2 EDC4 ITGB1BP1	8.92e-06	1038	47	9	26673895
Pubmed	Interactomes of Glycogen Synthase Kinase-3 Isoforms.	APC TANC1 TRAK2 EDC4 HECTD1	9.33e-06	209	47	5	36779422
Pubmed	Using an in situ proximity ligation assay to systematically profile endogenous protein-protein interactions in a pathway network.	APC FGF5 RICTOR MAPK8 BRAF RPS6KA5	1.05e-05	371	47	6	25241761
Pubmed	Huwe1-mediated ubiquitylation of dishevelled defines a negative feedback loop in the Wnt signaling pathway.	DVL2 DVL3	1.07e-05	4	47	2	24643799
Pubmed	The APC/C E3 Ligase Complex Activator FZR1 Restricts BRAF Oncogenic Function.	APC BRAF	1.07e-05	4	47	2	28174173
Pubmed	High detection rates of colorectal neoplasia by stool DNA testing with a novel digital melt curve assay.	APC BRAF	1.07e-05	4	47	2	19026650
Pubmed	A gene marker panel covering the Wnt and the Ras-Raf-MEK-MAPK signalling pathways allows to detect gene mutations in 80% of early (UICC I) colon cancer stages in humans.	APC BRAF	1.07e-05	4	47	2	19679059
Pubmed	Vitamin C selectively kills KRAS and BRAF mutant colorectal cancer cells by targeting GAPDH.	APC BRAF	1.07e-05	4	47	2	26541605
Pubmed	Bacterial-Driven Inflammation and Mutant BRAF Expression Combine to Promote Murine Colon Tumorigenesis That Is Sensitive to Immune Checkpoint Therapy.	APC BRAF	1.07e-05	4	47	2	33632774
Pubmed	Inhibition of the Wnt/beta-catenin pathway by the WWOX tumor suppressor protein.	DVL2 DVL3	1.07e-05	4	47	2	19465938
Pubmed	DCDC2 mutations cause a renal-hepatic ciliopathy by disrupting Wnt signaling.	DVL2 DVL3	1.07e-05	4	47	2	25557784
Pubmed	cDNA characterization and chromosomal mapping of two human homologues of the Drosophila dishevelled polarity gene.	DVL2 DVL3	1.07e-05	4	47	2	8817329
Pubmed	Human dishevelled genes constitute a DHR-containing multigene family.	DVL2 DVL3	1.07e-05	4	47	2	9192851
Pubmed	Mutations in the LRRK2 Roc-COR tandem domain link Parkinson's disease to Wnt signalling pathways.	DVL2 DVL3	1.07e-05	4	47	2	19625296
Pubmed	Loss of Dishevelleds disrupts planar polarity in ependymal motile cilia and results in hydrocephalus.	DVL2 DVL3	1.07e-05	4	47	2	25043421
Pubmed	Phosphorylation of Dishevelled by protein kinase RIPK4 regulates Wnt signaling.	DVL2 DVL3	1.07e-05	4	47	2	23371553
Pubmed	Wnt3a-mediated formation of phosphatidylinositol 4,5-bisphosphate regulates LRP6 phosphorylation.	DVL2 DVL3	1.07e-05	4	47	2	18772438
Pubmed	Activation of p53 by Dishevelled independent of Wnt or planar polarity pathways.	DVL2 DVL3	1.07e-05	4	47	2	17593335
Pubmed	DNMT3b Modulates Melanoma Growth by Controlling Levels of mTORC2 Component RICTOR.	RICTOR BRAF	1.07e-05	4	47	2	26923591
Pubmed	Single-Cell Profiling Reveals the Impact of Genetic Alterations on the Differentiation of Inflammation-Induced Murine Colon Tumors.	APC BRAF	1.07e-05	4	47	2	38893159
Pubmed	Planar cell polarity controls pancreatic beta cell differentiation and glucose homeostasis.	DVL2 DVL3 HNF1B	1.12e-05	32	47	3	23177622
Pubmed	Independent mutations in mouse Vangl2 that cause neural tube defects in looptail mice impair interaction with members of the Dishevelled family.	DVL2 DVL3	1.78e-05	5	47	2	15456783
Pubmed	The E3 ubiquitin ligase ITCH negatively regulates canonical Wnt signaling by targeting dishevelled protein.	DVL2 DVL3	1.78e-05	5	47	2	22826439
Pubmed	MGMT and MLH1 promoter methylation versus APC, KRAS and BRAF gene mutations in colorectal cancer: indications for distinct pathways and sequence of events.	APC BRAF	1.78e-05	5	47	2	19164452
Pubmed	DIX domains of Dvl and axin are necessary for protein interactions and their ability to regulate beta-catenin stability.	DVL3 APC	1.78e-05	5	47	2	10330181
Pubmed	Schwannomin-interacting protein-1 isoform IQCJ-SCHIP-1 is a late component of nodes of Ranvier and axon initial segments.	IQCJ-SCHIP1 IQCJ	1.78e-05	5	47	2	18550753
Pubmed	Axin contains three separable domains that confer intramolecular, homodimeric, and heterodimeric interactions involved in distinct functions.	DVL2 MAPK8	1.78e-05	5	47	2	15579909
Pubmed	HSF1 critically attunes proteotoxic stress sensing by mTORC1 to combat stress and promote growth.	RICTOR MAPK8	1.78e-05	5	47	2	27043084
Pubmed	Frat oncoproteins act at the crossroad of canonical and noncanonical Wnt-signaling pathways.	DVL2 MAPK8	1.78e-05	5	47	2	19802005
Pubmed	A novel Wnt5a-Frizzled4 signaling pathway mediates activity-independent dendrite morphogenesis via the distal PDZ motif of Frizzled 4.	DVL2 DVL3	1.78e-05	5	47	2	25424568
Pubmed	CYLD regulates spindle orientation by stabilizing astral microtubules and promoting dishevelled-NuMA-dynein/dynactin complex formation.	DVL2 DVL3	1.78e-05	5	47	2	24469800
Pubmed	Helicobacter pylori-induced activation of beta-catenin involves low density lipoprotein receptor-related protein 6 and Dishevelled.	DVL2 DVL3	1.78e-05	5	47	2	20137080
Pubmed	WD40-repeat 47, a microtubule-associated protein, is essential for brain development and autophagy.	EDC4 HERC1 MAPK8	2.21e-05	40	47	3	29078390
Pubmed	The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch.	DVL2 DVL3 APC TANC1 LIMCH1	2.48e-05	256	47	5	33397691
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	APC KMT2A PACS1 TBX3 RICTOR TANC1 ANKRD27	2.53e-05	650	47	7	38777146
Pubmed	Targeting E3 Ubiquitin Ligase WWP1 Prevents Cardiac Hypertrophy Through Destabilizing DVL2 via Inhibition of K27-Linked Ubiquitination.	DVL2 DVL3	2.67e-05	6	47	2	34139860
Pubmed	Expression of Muc19/Smgc gene products during murine sublingual gland development: cytodifferentiation and maturation of salivary mucous cells.	MUC16 MUC6	2.67e-05	6	47	2	19110483
Pubmed	The same pocket in menin binds both MLL and JUND but has opposite effects on transcription.	KMT2A MAPK8	2.67e-05	6	47	2	22327296
Pubmed	STAT3 serine phosphorylation by ERK-dependent and -independent pathways negatively modulates its tyrosine phosphorylation.	MAPK8 RPS6KA5	2.67e-05	6	47	2	9343414
Pubmed	Molecular genetic analysis of 103 sporadic colorectal tumours in Czech patients.	APC BRAF	2.67e-05	6	47	2	21901162
Pubmed	Repression of Stat3 activity by activation of mitogen-activated protein kinase (MAPK).	MAPK8 RPS6KA5	2.67e-05	6	47	2	9872331
Pubmed	Nuclear factor of activated T cells (NFAT) proteins repress canonical Wnt signaling via its interaction with Dishevelled (Dvl) protein and participate in regulating neural progenitor cell proliferation and differentiation.	DVL2 DVL3	2.67e-05	6	47	2	21880741
Pubmed	Serine phosphorylation and negative regulation of Stat3 by JNK.	MAPK8 RPS6KA5	2.67e-05	6	47	2	10521505
Pubmed	Wnt ligands influence tumour initiation by controlling the number of intestinal stem cells.	APC BRAF	2.67e-05	6	47	2	29556067
Pubmed	Cystic renal neoplasia following conditional inactivation of apc in mouse renal tubular epithelium.	APC HNF1B	2.67e-05	6	47	2	15550389
Pubmed	High expression of IGFBP7 in fibroblasts induced by colorectal cancer cells is co-regulated by TGF-β and Wnt signaling in a Smad2/3-Dvl2/3-dependent manner.	DVL2 DVL3	2.67e-05	6	47	2	24427302
Pubmed	Deletion of the Dishevelled family of genes disrupts anterior-posterior axis specification and selectively prevents mesoderm differentiation.	DVL2 DVL3	2.67e-05	6	47	2	32579954
Pubmed	SIRT1 regulates Dishevelled proteins and promotes transient and constitutive Wnt signaling.	DVL2 DVL3	2.67e-05	6	47	2	20439735
Pubmed	Dishevelled proteins regulate cell adhesion in mouse blastocyst and serve to monitor changes in Wnt signaling.	DVL2 DVL3	3.74e-05	7	47	2	17005174
Pubmed	Domains of axin involved in protein-protein interactions, Wnt pathway inhibition, and intracellular localization.	DVL2 APC	3.74e-05	7	47	2	10330403
Pubmed	Erythropoietin-induced serine 727 phosphorylation of STAT3 in erythroid cells is mediated by a MEK-, ERK-, and MSK1-dependent pathway.	MAPK8 RPS6KA5	3.74e-05	7	47	2	12763138
Pubmed	Dynamic and adaptive cancer stem cell population admixture in colorectal neoplasia.	APC BRAF	3.74e-05	7	47	2	35931031
Pubmed	Oncogenic BRAF, unrestrained by TGFβ-receptor signalling, drives right-sided colonic tumorigenesis.	APC BRAF	3.74e-05	7	47	2	34103493
Pubmed	Endogenous protein kinase CK2 participates in Wnt signaling in mammary epithelial cells.	DVL2 DVL3	3.74e-05	7	47	2	10806215
Pubmed	Murine dishevelled 3 functions in redundant pathways with dishevelled 1 and 2 in normal cardiac outflow tract, cochlea, and neural tube development.	DVL2 DVL3	3.74e-05	7	47	2	19008950
Pubmed	Protein encoded by the Axin(Fu) allele effectively down-regulates Wnt signaling but exerts a dominant negative effect on c-Jun N-terminal kinase signaling.	APC MAPK8	3.74e-05	7	47	2	18316368
Pubmed	Genetic correction of PSA values using sequence variants associated with PSA levels.	TBX3 HNF1B	3.74e-05	7	47	2	21160077
Pubmed	Cross-species regulatory network analysis identifies a synergistic interaction between FOXM1 and CENPF that drives prostate cancer malignancy.	APC BRAF	4.98e-05	8	47	2	24823640
Pubmed	Mammalian Ryk is a Wnt coreceptor required for stimulation of neurite outgrowth.	DVL2 DVL3	4.98e-05	8	47	2	15454084
Pubmed	G alpha o mediates WNT-JNK signaling through dishevelled 1 and 3, RhoA family members, and MEKK 1 and 4 in mammalian cells.	DVL3 MAPK8	4.98e-05	8	47	2	18187455
Pubmed	Regulation of AChR clustering by Dishevelled interacting with MuSK and PAK1.	DVL2 DVL3	4.98e-05	8	47	2	12165471
Pubmed	Sequence requirement and subtype specificity in the high-affinity interaction between human frizzled and dishevelled proteins.	DVL2 DVL3	4.98e-05	8	47	2	19388021
Pubmed	Cross talk between the Akt and p38α pathways in macrophages downstream of Toll-like receptor signaling.	RICTOR RPS6KA5	6.40e-05	9	47	2	23979601
Interaction	YWHAH interactions	APC KMT2A PACS1 RICTOR TANC1 LIMCH1 RIMS1 EDC4 HERC1 BRAF SSH1 HECTD1 ANKRD27 SRGAP1	9.10e-08	1102	46	14	int:YWHAH
Interaction	YWHAZ interactions	NEK4 APC KMT2A PACS1 RICTOR TANC1 CEP126 MAPK8 BRAF SSH1 RPS6KA5 HECTD1 ANKRD27 SRGAP1	8.15e-07	1319	46	14	int:YWHAZ
Interaction	YWHAB interactions	DVL2 NEK4 APC KMT2A RICTOR TANC1 MAPK8 BRAF SSH1 HECTD1 SRGAP1	1.30e-05	1014	46	11	int:YWHAB
Interaction	YWHAG interactions	DVL2 NEK4 APC KMT2A PACS1 RICTOR TANC1 EDC4 BRAF SSH1 HECTD1 SRGAP1	1.64e-05	1248	46	12	int:YWHAG
Interaction	YWHAE interactions	DVL2 NEK4 APC KMT2A PACS1 RICTOR TANC1 BRAF SSH1 HECTD1 ANKRD27 SRGAP1	1.75e-05	1256	46	12	int:YWHAE
Interaction	APC2 interactions	NEK4 APC DSCAM	1.91e-05	23	46	3	int:APC2
Interaction	GUSBP5 interactions	DVL2 TBX3 RICTOR ZFHX4	2.56e-05	75	46	4	int:GUSBP5
Interaction	CTNNB1 interactions	DVL2 DVL3 APC KMT2A TBX3 HNF1B TANC1 LIMCH1 MAPK8 HECTD1	7.43e-05	1009	46	10	int:CTNNB1
Interaction	CSNK2B interactions	DVL2 APC KMT2A PACS1 BRAF DSCAM RPS6KA5 BAZ2B	7.54e-05	625	46	8	int:CSNK2B
Interaction	PHLPP1 interactions	DVL2 DVL3 APC TANC1 LIMCH1 MAPK8	1.04e-04	333	46	6	int:PHLPP1
Interaction	TSPYL1 interactions	DVL2 DVL3 RICTOR HECTD1	1.41e-04	116	46	4	int:TSPYL1
Interaction	BMP15 interactions	NEK4 HECTD1	1.41e-04	8	46	2	int:BMP15
Interaction	PLK1 interactions	DVL2 DVL3 APC ZC3H7A RICTOR TRAK2 HECTD1	1.45e-04	510	46	7	int:PLK1
Interaction	SFN interactions	NEK4 APC KMT2A RICTOR TANC1 EDC4 BRAF HECTD1	1.53e-04	692	46	8	int:SFN
Interaction	TCEAL4 interactions	DVL2 HECTD1 ADGRG4	1.58e-04	46	46	3	int:TCEAL4
Interaction	HDAC1 interactions	DVL2 DVL3 APC KMT2A TBX3 HNF1B MAPK8 ZFHX4 STAG1 HECTD1	1.61e-04	1108	46	10	int:HDAC1
Interaction	EEF1AKMT3 interactions	DVL2 RICTOR HERC1 MAPK8 RPS6KA5 ANKRD27	1.70e-04	364	46	6	int:EEF1AKMT3
Interaction	RAPGEF4 interactions	RIMS1 DSCAM SRGAP1	2.02e-04	50	46	3	int:RAPGEF4
Interaction	XRCC6 interactions	DVL2 DVL3 NEK4 KMT2A TBX3 RICTOR HNF1B MAPK8 HECTD1	2.12e-04	928	46	9	int:XRCC6
Cytoband	2q24.2	TANC1 BAZ2B	2.34e-04	22	47	2	2q24.2
GeneFamily	CD molecules\|Mucins	MUC16 MUC22 MUC3A MUC6	6.10e-08	21	34	4	648
GeneFamily	Dishevelled segment polarity proteins\|PDZ domain containing	DVL2 DVL3	2.05e-05	4	34	2	505
GeneFamily	PDZ domain containing	DVL2 DVL3 RIMS1	2.88e-03	152	34	3	1220
GeneFamily	Rho GTPase activating proteins\|BCH domain containing	ARHGAP25 SRGAP1	3.97e-03	50	34	2	721
GeneFamily	Ankyrin repeat domain containing	TANC1 HECTD1 ANKRD27	1.04e-02	242	34	3	403
GeneFamily	PHD finger proteins	KMT2A BAZ2B	1.24e-02	90	34	2	88
GeneFamily	Tetratricopeptide repeat domain containing\|Bardet-Biedl syndrome associated\|BBSome	ZC3H7A TANC1	1.97e-02	115	34	2	769
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HNBML5	APC RIMS1 NRXN3 CEP126 HERC1 MAPK8 ZFHX4 DSCAM	1.58e-06	465	47	8	M39066
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HGABA	APC PACS1 RICTOR HNF1B RIMS1 NRXN3 CEP126 HERC1 ZFHX4 DSCAM SRGAP1	3.09e-06	1106	47	11	M39071
Coexpression	SHEN_SMARCA2_TARGETS_UP	APC ZC3H7A LIMCH1 TRAK2 STAG1 BAZ2B REV1	1.07e-05	429	47	7	M29
Coexpression	GSE29618_PRE_VS_DAY7_FLU_VACCINE_MDC_DN	DVL2 RIMS1 HERC1 MAPK8 ITGB1BP1	2.77e-05	198	47	5	M4981
Coexpression	GSE15330_HSC_VS_LYMPHOID_PRIMED_MULTIPOTENT_PROGENITOR_IKAROS_KO_UP	NEK4 KMT2A TBX3 MAPK8 ZFHX4	2.77e-05	198	47	5	M7050
Coexpression	GSE11057_CD4_CENT_MEM_VS_PBMC_UP	PCNX2 KMT2A PACS1 EDC4 ATXN7L1	2.77e-05	198	47	5	M3116
Coexpression	GAUTAM_EYE_IRIS_CILIARY_BODY_MEG3_HIGH_FIBROBLASTS	RICTOR ZFHX4 SSH1 BAZ2B	5.06e-05	113	47	4	M43610
Coexpression	RODRIGUES_DCC_TARGETS_DN	TBX3 LIMCH1 TRAK2 SSH1	6.19e-05	119	47	4	M15927
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HDA1	IQCJ-SCHIP1 RIMS1 NRXN3 MAPK8 ZFHX4 DSCAM SRGAP1	7.63e-05	584	47	7	M39068
Coexpression	LAKE_ADULT_KIDNEY_C20_COLLECTING_DUCT_INTERCALATED_CELLS_TYPE_A_CORTEX	LIMCH1 NRXN3 MAPK8 BRAF	1.60e-04	152	47	4	M39239
Coexpression	AIZARANI_LIVER_C20_LSECS_3	TANC1 LIMCH1 HERC1 SSH1 SRGAP1	1.82e-04	295	47	5	M39121
CoexpressionAtlas	DevelopingLowerUrinaryTract_e13.5_bladder mesenchyme_emap-3087_top-relative-expression-ranked_200	NEK4 BNC1 PRR16 FGF5 ZFHX4	2.91e-05	166	46	5	gudmap_developingLowerUrinaryTract_e13.5_bladder mesenchyme_200
CoexpressionAtlas	DevelopingLowerUrinaryTract_e13.5_bladder mesenchyme_emap-3087_top-relative-expression-ranked_500	NEK4 BNC1 PRR16 FGF5 LIMCH1 ZFHX4 SRGAP1	3.10e-05	420	46	7	gudmap_developingLowerUrinaryTract_e13.5_bladder mesenchyme_500
CoexpressionAtlas	FacebaseRNAseq_e10.5_Medial Nasal Eminence_top-relative-expression-ranked_1000_k-means-cluster#4	FGF5 ZC3H7A TBX3 HNF1B LIMCH1 CEP126	4.24e-05	298	46	6	Facebase_RNAseq_e10.5_Medial Nasal Eminence_1000_K4
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_top-relative-expression-ranked_1000	NEDD9 APC PRR16 TBX3 MAPK8 ZFHX4 SSH1 ATXN7L1 SRGAP1	4.88e-05	806	46	9	gudmap_developingLowerUrinaryTract_e14.5_ urethra_1000
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ bladder_emap-6668_k-means-cluster#1_top-relative-expression-ranked_1000	NEK4 BNC1 ZC3H7A NRXN3 ZFHX4 RPS6KA5	1.02e-04	349	46	6	DevelopingLowerUrinaryTract_e14.5_ bladder_emap-6668_k1_1000
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MUC16 TANC1 RIMS1 BAZ2B SRGAP1	1.26e-06	179	47	5	6e965e424eebef50f0202cff75f458be395cfca1
ToppCell	Tracheal-NucSeq\|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations	PACS1 LIMCH1 HERC1 STAG1 BAZ2B	2.12e-06	199	47	5	94b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCell	343B-Myeloid-Macrophage-SPP1+_Macrophage\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	NEK4 TBX3 IQCJ-SCHIP1 CCNB3	2.32e-05	158	47	4	de65af8d3b8514b17978155f31975e2347b75251
ToppCell	Control-Epithelial_cells-ECM-high_epithelial\|Control / group, cell type (main and fine annotations)	NEDD9 IQCJ-SCHIP1 TANC1 LIMCH1	3.09e-05	170	47	4	e2023d66e70983c87dacbd6181d3426488d1fc57
ToppCell	PND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PCNX2 BNC1 MUC16 FGF5	3.31e-05	173	47	4	3725525b99a6011eda2ff5459b4fd2e1eab1f090
ToppCell	PND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PCNX2 BNC1 MUC16 FGF5	3.31e-05	173	47	4	ee7d1429f23f1b89a9a9f7bc07a84a44cf7acd1c
ToppCell	PND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PCNX2 BNC1 MUC16 FGF5	3.31e-05	173	47	4	30d67738633493d47f06ae452424382f069b6c0a
ToppCell	PND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PCNX2 BNC1 MUC16 FGF5	3.39e-05	174	47	4	a9c6edf5c3fc119c24425f921c5566a8356c30fe
ToppCell	LPS-IL1RA+antiTNF\|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PRR16 LIMCH1 NRXN3 BAZ2B	3.62e-05	177	47	4	b7fee75de7e96924af488a5baa2334711889ae7c
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Neuronal-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCNX2 BNC1 NRXN3 IQCJ	3.70e-05	178	47	4	1bddbc083c36657bd6910f7466126ab325e88176
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Neuronal-neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCNX2 BNC1 NRXN3 IQCJ	3.70e-05	178	47	4	a74e5a390cbeaca9de1fdb7b2a0e50783bd202dd
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCNX2 BNC1 NRXN3 IQCJ	3.78e-05	179	47	4	a3922476f33d2e4137a12dbda21a1703dff79684
ToppCell	P03-Mesenchymal-mesenchymal_fibroblast-mesothelial_cell_of_visceral_pleura\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PCNX2 BNC1 MUC16 FGF5	3.86e-05	180	47	4	2ccc77d769d3ffd77ab3af45e4f192785b6db79c
ToppCell	E17.5-Mesenchymal-mesenchymal_fibroblast-mesothelial_cell_of_visceral_pleura\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PCNX2 BNC1 MUC16 FGF5	4.21e-05	184	47	4	607b55022de21ddb6a2d75e085df76df7abf6624
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PRR16 TBX3 RIMS1 ZFHX4	4.30e-05	185	47	4	3b2dfc8f4c87be516265dbecfc251276034d0efd
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1-D175\|Adult / Lineage, Cell type, age group and donor	IQCJ-SCHIP1 TANC1 LIMCH1 DSCAM	4.30e-05	185	47	4	32b4e68e551d435a732f253f6ad83408c759a642
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	KMT2A RICTOR HERC1 BRAF	4.58e-05	188	47	4	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	control-Myeloid-Neutrophils_1\|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	NEDD9 RICTOR ARHGAP25 RPS6KA5	4.87e-05	191	47	4	db1b3cd07d7d190155b2d14e82e1d124975fbd0b
ToppCell	COVID-19-Fibroblasts-Alveolar_FB\|COVID-19 / group, cell type (main and fine annotations)	PRR16 TANC1 LIMCH1 SRGAP1	5.27e-05	195	47	4	603050beeb33c331d4b2e3fa46cae3f3e0e4bdc7
ToppCell	Control-Control-Lymphocyte-T/NK-NK_activated\|Control / Disease, condition lineage and cell class	ARHGAP25 TANC1 EDC4 HERC1	5.60e-05	198	47	4	76d5fe4e5bbe6c73a6ca409b80b5c3924e07cab7
ToppCell	Parenchymal-NucSeq\|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations	TANC1 LIMCH1 BRAF STAG1	5.60e-05	198	47	4	1996373bdccc55aac347d349bd22f6aad6d0c668
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Newborn-35\|World / Primary Cells by Cluster	KMT2A NRXN3 MAPK8 BAZ2B	5.60e-05	198	47	4	de5214a85fe017eb23d4aa8af624464f062ec57e
ToppCell	Tracheal-NucSeq-Epithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MUC16 TANC1 LIMCH1 SRGAP1	5.82e-05	200	47	4	d3af0a706baf66e3f32e67b17dcfc31e5b32ce0e
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-2m-Neuronal-Intermediate\|2m / Sample Type, Dataset, Time_group, and Cell type.	MAPK8 HECTD1 BAZ2B SRGAP1	5.82e-05	200	47	4	2a635694844ddabcd98462c5636a6f41a3f08a46
ToppCell	Tracheal-NucSeq-Epithelial-Epi_submucosal-gland\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MUC16 TANC1 LIMCH1 SRGAP1	5.82e-05	200	47	4	0eb9ad8c0373bcc62029ec21c590ed03aaacd039
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L6_CT-L6_CT_ALM_Nxph2_Sla\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	FGF5 ARHGAP25 ADGRG4	1.47e-04	97	47	3	0d68bf2dfb9c221375b70b055f735536afb18f65
ToppCell	COVID-19-kidney-Technical/muscle_(EC)\|kidney / Disease (COVID-19 only), tissue and cell type	MUC16 NRXN3 ADGRG4	4.24e-04	139	47	3	64c35411bbe67acb5010dadc4b0b1be0f8b17737
ToppCell	3'-GW_trimst-1-SmallIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RIMS1 NRXN3 BAZ2B	4.60e-04	143	47	3	39060dc1d87505a16e2df95140087c731f099570
ToppCell	367C-Myeloid-Macrophage-SPP1+_Macrophage_2\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	NEDD9 MUC16 BRAF	4.70e-04	144	47	3	38ff324366ad5be626e3657c1e33277fc36ddd4c
ToppCell	10x5'-Liver-Lymphocytic_T_CD4/8-lo-Trm_Tgd\|Liver / Manually curated celltypes from each tissue	RPS6KA5 ANKRD27 REV1	5.71e-04	154	47	3	c6308074468235c88ef4ea43ab155d9f86cbf261
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW13-Neuronal-Cortical_neuron\|GW13 / Sample Type, Dataset, Time_group, and Cell type.	RICTOR LIMCH1	5.87e-04	34	47	2	6c9c477b43009cded5a2e1a1792c32c40d9309a8
ToppCell	PND07-28-samps-Mesenchymal-Mesothelial-Mesothelial\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	PCNX2 BNC1 MUC16	5.93e-04	156	47	3	605d95a900e1443d3f6aae163ef2e893d3293203
ToppCell	E18.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-Sox9_Epi-Sox9_Epi_prolif\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PCNX2 ZFHX4 IQCJ	5.93e-04	156	47	3	b28bbdb515317368f1231b0b15d7442352f3b400
ToppCell	PND07-28-samps-Mesenchymal-Mesothelial\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	PCNX2 BNC1 MUC16	5.93e-04	156	47	3	574f761962a7dd3308bd41fc529dd3ea1b8625f8
ToppCell	COVID-19-lung-Mesothelial\|lung / Disease (COVID-19 only), tissue and cell type	BNC1 MUC16 ZFHX4	5.93e-04	156	47	3	e1f563869b3bf997eaa2e756e31b53db1a478903
ToppCell	343B-Myeloid-Macrophage-SPP1+_Macrophage\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	TBX3 IQCJ-SCHIP1 CCNB3	6.04e-04	157	47	3	4183dbed6b31ebe13ef33eb19ba6d0fb4f625953
ToppCell	droplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NEK4 BRAF RPS6KA5	6.04e-04	157	47	3	a426c54fd1545093d41426e9620862f71bd06f6b
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MUC16 RIMS1 DSCAM	6.27e-04	159	47	3	60b1f4dce2ce0911160fda17f137c064da31e2eb
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-myeloid-myeloid_macrophage-microglial_cell\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	MUC22 DSCAM SRGAP1	6.27e-04	159	47	3	31ec8222c766cb614e1cf27f74ee9d99489eca5c
ToppCell	COVID-19-kidney-Technical/muscle_(Mes)\|kidney / Disease (COVID-19 only), tissue and cell type	RIMS1 NRXN3 DSCAM	6.27e-04	159	47	3	5335cbcdeaf2bbd0268bbfe0e45c8c0d288e640d
ToppCell	Children_(3_yrs)-Epithelial-lung_goblet_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	MUC16 RIMS1 NRXN3	6.50e-04	161	47	3	2d63b279d9a5132e1c09b03930bf9039036d24a2
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal--glomerular_mesenchymal_cell-Renin-positive_Juxtaglomerular_Granular_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PRR16 TBX3 NRXN3	6.85e-04	164	47	3	43630a448f4369fa9e4e3eccdf3b9f29cec16c39
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PRR16 TBX3 NRXN3	6.85e-04	164	47	3	108fbecb56d69a675d6ce6e826a873ae528f2fd7
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal--glomerular_mesenchymal_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PRR16 TBX3 NRXN3	6.85e-04	164	47	3	46208f18325976c89f572f6627aea0582142b92d
ToppCell	COVID-19-lung-Mesothelial\|COVID-19 / Disease (COVID-19 only), tissue and cell type	BNC1 MUC16 ZFHX4	6.85e-04	164	47	3	83303e2ba52008391b8dc3fae8225ab5bcb20063
ToppCell	368C-Fibroblasts-Fibroblast-J_(Lipofibroblast)-\|368C / Donor, Lineage, Cell class and subclass (all cells)	BNC1 MUC16 RIMS1	7.10e-04	166	47	3	4d63c758d46e73311b864148c646bf081498dee7
ToppCell	368C-Fibroblasts-Fibroblast-J_(Lipofibroblast)\|368C / Donor, Lineage, Cell class and subclass (all cells)	BNC1 MUC16 RIMS1	7.10e-04	166	47	3	4160ccf9291072a6e2782f9ad141bc9a9747f3ad
ToppCell	Club_cells-IPF_01\|World / lung cells shred on cell class, cell subclass, sample id	FGF5 RIMS1 MUC6	7.10e-04	166	47	3	a440aa338aa0c6cd0b5800dfa7e83f8ca16fce1a
ToppCell	Control-Epithelial-Mesothelial\|Control / Disease state, Lineage and Cell class	BNC1 MUC16 ZFHX4	7.10e-04	166	47	3	1ed3788257e14f097862b999f020bfe2a57de52b
ToppCell	PND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	BNC1 MUC16 MUC6	7.22e-04	167	47	3	d50311b1f66f143bae4c4cf50e2e9b13c85d6920
ToppCell	PND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PCNX2 BNC1 MUC16	7.22e-04	167	47	3	351f8de1fbdf742ac74f9099b254d515ab539bb2
ToppCell	PND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PCNX2 BNC1 MUC16	7.22e-04	167	47	3	c042d6cdddd0e1ddef1e3ac6f4fe23151127b0f2
ToppCell	PND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	BNC1 MUC16 MUC6	7.22e-04	167	47	3	7abc785e688a384672d7fb5a62d32538fe7e5a51
ToppCell	3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MUC16 TANC1 ANKRD27	7.35e-04	168	47	3	de0b00bc405c898d08a06b2e585fb62c0ab9a66e
ToppCell	368C-Fibroblasts-Fibroblast-J_(Lipofibroblast)\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	BNC1 MUC16 RIMS1	7.35e-04	168	47	3	e870d2e69316406f45112ed0bf324b24f902a99e
ToppCell	Control\|World / group, cell type (main and fine annotations)	NEDD9 LIMCH1 NRXN3	7.35e-04	168	47	3	a3511faf2cd2c2b9c8363c8b99da3f3609c43ed6
ToppCell	368C-Fibroblasts-Fibroblast-J_(Lipofibroblast)-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	BNC1 MUC16 RIMS1	7.35e-04	168	47	3	403aba73a0f9ffb32252288d075fad8a588ca440
ToppCell	3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	BNC1 NRXN3 STAG1	7.74e-04	171	47	3	eddc5e05003382603ee49f74b9e2242a43021096
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FGF5 RIMS1 NRXN3	7.74e-04	171	47	3	99176a932569fa1c7e1c01009684f5a65244b96e
ToppCell	droplet-Kidney-nan-3m-Epithelial-Pecam____kidney_capillary_endothelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TBX3 NRXN3 SRGAP1	7.87e-04	172	47	3	073a503dc922e3e3ac3528e249b0f8b74402110b
ToppCell	343B-Fibroblasts-Fibroblast-B_(Myofibroblast)\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	HNF1B ARHGAP25 HERC1	7.87e-04	172	47	3	c6bc78fd63c9479a84ec0552b55c89750cad0fa5
ToppCell	P07-Mesenchymal-mesenchymal_fibroblast-mesothelial_cell_of_visceral_pleura\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PCNX2 BNC1 MUC16	7.87e-04	172	47	3	9a256db817c1af1802203cc88a55d608fb328c63
ToppCell	343B-Fibroblasts-Fibroblast-B_(Myofibroblast)-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	HNF1B ARHGAP25 HERC1	7.87e-04	172	47	3	bfb87a281a9cf6ad45b310bf8104fc0ab382b549
ToppCell	367C-Fibroblasts-Fibroblast-J_(Lipofibroblast)-\|367C / Donor, Lineage, Cell class and subclass (all cells)	BNC1 MUC16 IQCJ-SCHIP1	8.00e-04	173	47	3	e05cddf5bf63cf419343ff229453327519765be8
ToppCell	367C-Fibroblasts-Fibroblast-J_(Lipofibroblast)\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	BNC1 MUC16 IQCJ-SCHIP1	8.00e-04	173	47	3	3d7c281a1a9f183a5a861d1a9c7b50d216535893
ToppCell	PBMC-Control-Myeloid-cDC-cDC-cDC_10\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	LIMCH1 ZFHX4 SRGAP1	8.00e-04	173	47	3	09a13407a41ff2cba82fc417b72bf9a24ce6c42e
ToppCell	367C-Fibroblasts-Fibroblast-J_(Lipofibroblast)\|367C / Donor, Lineage, Cell class and subclass (all cells)	BNC1 MUC16 IQCJ-SCHIP1	8.00e-04	173	47	3	74ad5ed33821b8816c9c8e67c50ee4496ba18e2f
ToppCell	PBMC-Control-Myeloid-cDC-cDC-cDC_10\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	LIMCH1 ZFHX4 SRGAP1	8.00e-04	173	47	3	bfec038a6783f166240da4861e100643c6ea80a5
ToppCell	Children_(3_yrs)-Epithelial-lung_goblet_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	MUC16 RIMS1 NRXN3	8.00e-04	173	47	3	464267a2ff3f5c387b6c9c6fa4dab135a221f448
ToppCell	367C-Fibroblasts-Fibroblast-J_(Lipofibroblast)-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	BNC1 MUC16 IQCJ-SCHIP1	8.00e-04	173	47	3	3aa90578371039f81b7c6fa873ec70f8f2bc7dfa
ToppCell	Adult-Epithelial-lung_goblet_cell-D231\|Adult / Lineage, Cell type, age group and donor	MUC16 RIMS1 NRXN3	8.13e-04	174	47	3	7d2f802f493f19a068e097b2909a9000e2160266
ToppCell	Control-Epithelial_cells-AT1\|Control / group, cell type (main and fine annotations)	NEDD9 IQCJ-SCHIP1 LIMCH1	8.13e-04	174	47	3	548d7f2b958a2bfd2c95eb049ceaab55a559c77d
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PRR16 IQCJ-SCHIP1 IQCJ	8.13e-04	174	47	3	b3cd22e717d178269e6d5bd5ed7b2d945cd8ea25
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_PRSS12\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PRR16 IQCJ-SCHIP1 IQCJ	8.13e-04	174	47	3	ae363ce736fc8af439f3ad594d7bc2e344db80d4
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Neuronal-interneuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RIMS1 NRXN3 STAG1	8.27e-04	175	47	3	65571d775d26a40e979dbf290a8e4320c0d9fb3f
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PRR16 LIMCH1 NRXN3	8.27e-04	175	47	3	316f2ea930437bf1243b1c0f45e6bd864112c6f2
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PRR16 LIMCH1 NRXN3	8.27e-04	175	47	3	a9f08e1e4c2997dcdd3e5d92daac480da19100b8
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_PRSS12\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PRR16 IQCJ-SCHIP1 IQCJ	8.41e-04	176	47	3	40993c41c1017b53039a337174fc56632b278609
ToppCell	droplet-Kidney-KIDNEY-30m-Endothelial-Pecam____kidney_capillary_endothelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TBX3 LIMCH1 SRGAP1	8.41e-04	176	47	3	c4d9166e5bbb7ca544107db14e4374289f5de6bd
ToppCell	droplet-Kidney-KIDNEY-30m-Endothelial-kidney_capillary_endothelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TBX3 LIMCH1 SRGAP1	8.41e-04	176	47	3	d58ef51002ea50b3037636038214bbb7454cb503
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_PRSS12\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PRR16 IQCJ-SCHIP1 IQCJ	8.55e-04	177	47	3	f902600c639087664316b3cf30cab243bc3d1c5c
ToppCell	10x5'v1-week_17-19-Myeloid_macrophage-stroma-erythroid_macrophage\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	TRAK2 MUC6 SRGAP1	8.55e-04	177	47	3	b647667da62a91dbe3890820142626e26aa779d2
ToppCell	Fetal_29-31_weeks-Epithelial-lung_goblet_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	MUC16 RIMS1 NRXN3	8.55e-04	177	47	3	a4c001a8e44142babf9f24dfe6f7b73a70b11b16
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma\|TCGA-Brain / Sample_Type by Project: Shred V9	KMT2A RICTOR HERC1	8.55e-04	177	47	3	e8ab340b20cd41554c3841fe980e078e878af35f
ToppCell	Fetal_29-31_weeks-Epithelial-lung_goblet_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	MUC16 RIMS1 NRXN3	8.55e-04	177	47	3	363e07b0f347f3716d530a28ead854b98e27d37c
ToppCell	P28-Mesenchymal-mesenchymal_fibroblast-mesothelial_cell_of_visceral_pleura\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PCNX2 BNC1 MUC16	8.69e-04	178	47	3	1e05bc26591fea16e29bcfc5f538dda1dc427f05
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.2.3\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NEDD9 HNF1B LIMCH1	8.69e-04	178	47	3	f3b5eeca6081d65d48824b5d13e3b8eb5fdeb2dd
ToppCell	Adult-Epithelial-lung_goblet_cell\|Adult / Lineage, Cell type, age group and donor	MUC16 RIMS1 NRXN3	8.83e-04	179	47	3	1fc1f252ca943a2f649d1e627f56acbf15f8e058
ToppCell	nucseq-Epithelial-Epithelial_Glandular\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MUC16 RIMS1 MUC3A	8.83e-04	179	47	3	859cd8ee414ad6207c046ada2e655e49322dd01c
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PRR16 RIMS1 ZFHX4	8.83e-04	179	47	3	02c90d8306016365ed811f0c63cfb3ac7b85464c
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	IQCJ-SCHIP1 LIMCH1 DSCAM	8.83e-04	179	47	3	4f6ca313b78aa93557937a046c44dcf8bcc9963c
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L2-4_RORB_GRIK1\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PRR16 IQCJ-SCHIP1 IQCJ	8.97e-04	180	47	3	fd8c2059fcb382ffbfe19e598e37a49e1d5637b5
ToppCell	nucseq-Epithelial-Epithelial_Glandular-Goblet\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MUC16 RIMS1 MUC3A	8.97e-04	180	47	3	3dc80bc636bf0e6ffc9762853132a9fe59fd1f66
ToppCell	nucseq-Epithelial-Epithelial_Glandular-Goblet-Goblet\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MUC16 RIMS1 MUC3A	8.97e-04	180	47	3	668a2d8e1d5a390309d5eb62c836f5903144bea9
ToppCell	wk_15-18-Mesenchymal-Chondrocyte\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	FGF5 TBX3 RPS6KA5	9.12e-04	181	47	3	8950844b3e65c7028d80da5787ae2ce509c3d52d
ToppCell	COVID-19-Heart-Pericyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PRR16 RIMS1 MUC3A	9.12e-04	181	47	3	33cac65ed1ea5e7bd72250495df4f850b143d5aa
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NEDD9 HNF1B IQCJ-SCHIP1	9.12e-04	181	47	3	6956ecd6264f7469a25e555673bce4eb97d28f7a
ToppCell	TCGA-Skin-Metastatic-Melanoma-Skin_Cutaneous_Melanoma-2\|TCGA-Skin / Sample_Type by Project: Shred V9	TANC1 TRAK2 RPS6KA5	9.12e-04	181	47	3	9d5b331cabc5524f0a9fd8b571e87be4c447c7d4
ToppCell	pdx-Tumor_cells-T6\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	NEDD9 NRXN3 ZFHX4	9.26e-04	182	47	3	7b24a4f712e1ae1525e8f1c8ec4e1fc43489cbee
ToppCell	Children_(3_yrs)-Epithelial-lung_goblet_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	MUC16 RIMS1 NRXN3	9.26e-04	182	47	3	3f1a666fe27dd7529c114539ed5f6b8ca585c875
Drug	AC1NDQQF	DVL2 DVL3 APC MAPK8	2.24e-06	46	46	4	CID004630071
Drug	S(+)-Terguride [37686-84-3]; Down 200; 11.8uM; PC3; HT_HG-U133A	NEDD9 APC FGF5 HNF1B EDC4 BRAF	2.65e-06	196	46	6	6299_DN
Drug	retinoic acid; Up 200; 1uM; MCF7; HT_HG-U133A	DVL3 PACS1 TBX3 LIMCH1 MAPK8	2.41e-05	171	46	5	5208_UP
Drug	LY 294002; Up 200; 10uM; MCF7; HT_HG-U133A_EA	DVL2 PCNX2 NEDD9 KMT2A RPS6KA5	3.42e-05	184	46	5	1007_UP
Drug	PHA-00851261E [724719-49-7]; Down 200; 10uM; PC3; HT_HG-U133A	DVL2 NEDD9 APC HNF1B ATXN7L1	4.30e-05	193	46	5	3773_DN
Drug	(-)-Isoproterenol hydrochloride [5984-95-2]; Down 200; 16.2uM; PC3; HT_HG-U133A	PCNX2 APC PRR16 FGF5 EDC4	4.51e-05	195	46	5	4495_DN
Drug	Isoconazole [27523-40-6]; Down 200; 9.6uM; PC3; HT_HG-U133A	PCNX2 KMT2A HNF1B HERC1 SSH1	4.62e-05	196	46	5	2056_DN
Drug	Tinidazole [19387-91-8]; Up 200; 16.2uM; MCF7; HT_HG-U133A	APC PACS1 TBX3 RIMS1 MAPK8	4.62e-05	196	46	5	3896_UP
Drug	Norgestrel-(-)-D [797-63-7]; Down 200; 12.8uM; PC3; HT_HG-U133A	PCNX2 APC FGF5 PACS1 HNF1B	4.74e-05	197	46	5	3708_DN
Drug	Isoquinoline, 6,7-dimethoxy-1-methyl-1,2,3,4-tetrahydro, hydrochloride; Up 200; 16.4uM; PC3; HT_HG-U133A	BNC1 KMT2A LIMCH1 BRAF ATXN7L1	4.74e-05	197	46	5	4226_UP
Drug	Androsterone [53-41-8]; Up 200; 13.8uM; MCF7; HT_HG-U133A	DVL3 PCNX2 BNC1 HNF1B MAPK8	4.85e-05	198	46	5	2650_UP
Drug	Harmane hydrochloride [21655-84-5]; Down 200; 18.2uM; PC3; HT_HG-U133A	APC HNF1B MAPK8 STAG1 ATXN7L1	4.85e-05	198	46	5	4584_DN
Drug	Clindamycin hydrochloride [21462-39-5]; Up 200; 8.6uM; MCF7; HT_HG-U133A	DVL2 PACS1 MAPK8 RPS6KA5 MUC6	4.97e-05	199	46	5	7172_UP
Drug	Ifosfamide [3778-73-2]; Down 200; 15.4uM; MCF7; HT_HG-U133A	NEDD9 APC LIMCH1 MAPK8 DSCAM	4.97e-05	199	46	5	3485_DN
Drug	methenamine silver	DVL2 DVL3 KMT2A MAPK8 SRGAP1	5.21e-05	201	46	5	CID000004101
Drug	Chloroprene	NEDD9 BNC1 LIMCH1 TRAK2 MAPK8 ZFHX4 RPS6KA5 HECTD1 BAZ2B ITGB1BP1 REV1	5.87e-05	1348	46	11	ctd:D002737
Drug	p-hydroxymandelonitrile	DVL2 DVL3 APC KMT2A	9.15e-05	117	46	4	CID000166768
Drug	deltaMID	DVL2 MAPK8	1.42e-04	9	46	2	CID000192085
Drug	AC1NE2UB	APC TBX3 EDC4	1.98e-04	56	46	3	CID004635684
Drug	Methylene Chloride	NEDD9 BNC1 HERC1 ZFHX4	3.27e-04	163	46	4	ctd:D008752
Drug	11-deoxojervine	DVL2 APC TBX3 HNF1B	4.37e-04	176	46	4	CID000020518
Drug	Withaferin A [5119-48-2]; Down 200; 1uM; MCF7; HT_HG-U133A	NEDD9 APC LIMCH1 DSCAM	4.96e-04	182	46	4	4376_DN
Drug	Rapamycin; Up 200; 0.1uM; MCF7; HT_HG-U133A_EA	DVL2 NEDD9 LIMCH1 RPS6KA5	5.27e-04	185	46	4	1022_UP
Drug	LY 294002; Up 200; 10uM; MCF7; HT_HG-U133A	NEDD9 MAPK8 DSCAM RPS6KA5	5.38e-04	186	46	4	1664_UP
Drug	C768-0445; Up 200; 10uM; MCF7; HT_HG-U133A_EA	DVL3 NEDD9 DSCAM RPS6KA5	5.72e-04	189	46	4	973_UP
Drug	Nocodazole [31430-18-9]; Up 200; 13.2uM; PC3; HT_HG-U133A	APC KMT2A PACS1 NRXN3	5.83e-04	190	46	4	7145_UP
Drug	Rapamycin; Up 200; 0.1uM; MCF7; HT_HG-U133A	NEDD9 RPS6KA5 ATXN7L1 MUC6	5.95e-04	191	46	4	5581_UP
Drug	Rapamycin; Down 200; 0.1uM; MCF7; HT_HG-U133A_EA	APC KMT2A EDC4 REV1	5.95e-04	191	46	4	1059_DN
Drug	GSK525762A	APC KMT2A	5.99e-04	18	46	2	ctd:C554645
Drug	5279552; Up 200; 22uM; MCF7; HT_HG-U133A_EA	NEDD9 APC DSCAM RPS6KA5	6.06e-04	192	46	4	960_UP
Drug	Rapamycin; Up 200; 0.1uM; MCF7; HT_HG-U133A	APC TBX3 NRXN3 RPS6KA5	6.06e-04	192	46	4	5567_UP
Drug	Naltrexone hydrochloride dihydrate [16676-29-2]; Up 200; 9.6uM; MCF7; HT_HG-U133A	DVL3 APC KMT2A TBX3	6.18e-04	193	46	4	2209_UP
Drug	Ketotifen fumarate [34580-14-8]; Down 200; 9.4uM; MCF7; HT_HG-U133A	DVL3 NEDD9 LIMCH1 BRAF	6.18e-04	193	46	4	3200_DN
Drug	troglitazone; Down 200; 10uM; PC3; HG-U133A	PCNX2 PRR16 FGF5 PACS1	6.18e-04	193	46	4	431_DN
Drug	0173570-0000 [211245-44-2]; Up 200; 10uM; MCF7; HT_HG-U133A	PCNX2 TBX3 DSCAM MUC6	6.18e-04	193	46	4	4712_UP
Drug	Moroxidine hydrochloride [3160-91-6]; Down 200; 19.2uM; PC3; HT_HG-U133A	APC FGF5 LIMCH1 ATXN7L1	6.30e-04	194	46	4	6705_DN
Drug	Coralyne chloride hydrate [38989-38-7]; Up 200; 9.6uM; MCF7; HT_HG-U133A	APC RIMS1 MAPK8 ZFHX4	6.30e-04	194	46	4	5418_UP
Drug	Demeclocycline hydrochloride [64-73-3]; Up 200; 8uM; MCF7; HT_HG-U133A	PCNX2 NEDD9 LIMCH1 RPS6KA5	6.30e-04	194	46	4	3404_UP
Drug	(R) -Naproxen sodium salt [26159-34-2]; Down 200; 15.8uM; MCF7; HT_HG-U133A	DVL2 NEDD9 APC DSCAM	6.30e-04	194	46	4	6794_DN
Drug	16-phenyl tetranor Prostaglandin E2; Down 200; 10uM; PC3; HT_HG-U133A	DVL2 PRR16 LIMCH1 STAG1	6.43e-04	195	46	4	7509_DN
Drug	Tiapride hydrochloride [51012-33-0]; Up 200; 11uM; MCF7; HT_HG-U133A	NEK4 NEDD9 APC LIMCH1	6.43e-04	195	46	4	4686_UP
Drug	Talampicillin hydrochloride [39878-70-1]; Up 200; 7.8uM; PC3; HT_HG-U133A	APC FGF5 LIMCH1 NRXN3	6.43e-04	195	46	4	7254_UP
Drug	Etifenin [63245-28-3]; Down 200; 12.4uM; MCF7; HT_HG-U133A	DVL2 NEDD9 HNF1B MAPK8	6.43e-04	195	46	4	4117_DN
Drug	Butoconazole nitrate [32872-77-1]; Up 200; 8.4uM; PC3; HT_HG-U133A	DVL2 DVL3 ARHGAP25 NRXN3	6.43e-04	195	46	4	6288_UP
Drug	Folic acid [59-30-3]; Up 200; 9uM; MCF7; HT_HG-U133A	PACS1 MAPK8 DSCAM RPS6KA5	6.43e-04	195	46	4	7201_UP
Drug	WY-14643; Up 200; 100uM; MCF7; HG-U133A	DVL2 DVL3 MAPK8 DSCAM	6.43e-04	195	46	4	368_UP
Drug	Methoxy-8-psoralen [298-81-7]; Down 200; 18.6uM; PC3; HT_HG-U133A	DVL2 APC MAPK8 ATXN7L1	6.43e-04	195	46	4	6661_DN
Drug	Ergocryptine-alpha [511-09-1]; Up 200; 7uM; PC3; HT_HG-U133A	APC ARHGAP25 LIMCH1 NRXN3	6.55e-04	196	46	4	3817_UP
Drug	Pheniramine maleate [132-20-7]; Down 200; 11.2uM; MCF7; HT_HG-U133A	DVL2 PCNX2 APC DSCAM	6.55e-04	196	46	4	4130_DN
Drug	Molindone hydrochloride [15622-65-8]; Up 200; 12.8uM; MCF7; HT_HG-U133A	NEK4 APC RIMS1 ZFHX4	6.55e-04	196	46	4	4784_UP
Drug	Chenodiol [474-25-9]; Up 200; 10.2uM; PC3; HT_HG-U133A	NEDD9 APC MAPK8 ATXN7L1	6.55e-04	196	46	4	7310_UP
Drug	Cefmetazole sodium salt [56796-39-5]; Down 200; 8.2uM; MCF7; HT_HG-U133A	PCNX2 DSCAM RPS6KA5 BAZ2B	6.55e-04	196	46	4	7222_DN
Drug	2-Aminobenzenesulfonamide [3306-62-5]; Up 200; 23.2uM; MCF7; HT_HG-U133A	PCNX2 FGF5 RIMS1 ATXN7L1	6.55e-04	196	46	4	3400_UP
Drug	Aceclofenac [89796-99-6]; Down 200; 11.2uM; MCF7; HT_HG-U133A	NEDD9 SSH1 DSCAM RPS6KA5	6.55e-04	196	46	4	7029_DN
Drug	Parbendazole [14255-87-9]; Up 200; 16.2uM; MCF7; HT_HG-U133A	PCNX2 APC TBX3 MAPK8	6.55e-04	196	46	4	4357_UP
Drug	Acyclovir [59277-89-3]; Up 200; 17.8uM; PC3; HT_HG-U133A	APC KMT2A FGF5 ATXN7L1	6.55e-04	196	46	4	4683_UP
Drug	Sulfapyridine [144-83-2]; Up 200; 16uM; MCF7; HT_HG-U133A	APC PRR16 TBX3 HNF1B	6.55e-04	196	46	4	6101_UP
Drug	Ribavirin [36791-04-5]; Up 200; 16.4uM; PC3; HT_HG-U133A	DVL3 FGF5 PACS1 MAPK8	6.55e-04	196	46	4	7316_UP
Drug	Cefoperazone dihydrate; Down 200; 5.8uM; PC3; HT_HG-U133A	APC BNC1 PACS1 ANKRD27	6.55e-04	196	46	4	6323_DN
Drug	Gossypol [303-45-7]; Down 200; 7.8uM; PC3; HT_HG-U133A	DVL2 PCNX2 APC FGF5	6.55e-04	196	46	4	4296_DN
Drug	Norfloxacin [70458-96-7]; Up 200; 12.6uM; MCF7; HT_HG-U133A	APC KMT2A MAPK8 ZFHX4	6.55e-04	196	46	4	5985_UP
Drug	Piromidic acid [19562-30-2]; Down 200; 13.8uM; PC3; HT_HG-U133A	APC BNC1 HNF1B ATXN7L1	6.68e-04	197	46	4	4575_DN
Drug	Ajmaline [4360-12-7]; Up 200; 12.2uM; MCF7; HT_HG-U133A	APC KMT2A MAPK8 DSCAM	6.68e-04	197	46	4	7484_UP
Drug	Mexiletine hydrochloride [5370-01-4]; Up 200; 18.6uM; MCF7; HT_HG-U133A	APC FGF5 HNF1B MAPK8	6.68e-04	197	46	4	2324_UP
Drug	Succinylsulfathiazole [116-43-8]; Down 200; 11.2uM; MCF7; HT_HG-U133A	DVL3 PACS1 LIMCH1 DSCAM	6.68e-04	197	46	4	4847_DN
Drug	Morantel tartrate [26155-31-7]; Down 200; 10.8uM; PC3; HT_HG-U133A	NEK4 HNF1B TRAK2 HERC1	6.68e-04	197	46	4	1798_DN
Drug	Propidium iodide [25535-16-4]; Down 200; 6uM; PC3; HT_HG-U133A	PCNX2 APC PACS1 NRXN3	6.68e-04	197	46	4	5803_DN
Drug	Ajmalicine hydrochloride [4373-34-6]; Up 200; 10.2uM; PC3; HT_HG-U133A	DVL2 LIMCH1 NRXN3 MAPK8	6.68e-04	197	46	4	6360_UP
Drug	Fluorocurarine chloride [22273-09-2]; Up 200; 11.6uM; PC3; HT_HG-U133A	FGF5 PACS1 NRXN3 MUC6	6.68e-04	197	46	4	5741_UP
Drug	Altretamine [654-05-6]; Up 200; 19uM; PC3; HT_HG-U133A	APC BNC1 RIMS1 MUC6	6.68e-04	197	46	4	4627_UP
Drug	Cytisine (-) [485-35-8]; Up 200; 21uM; MCF7; HT_HG-U133A	DVL3 FGF5 LIMCH1 ZFHX4	6.68e-04	197	46	4	2759_UP
Drug	Mephenesin [59-47-2]; Down 200; 22uM; PC3; HT_HG-U133A	NEDD9 APC LIMCH1 BAZ2B	6.68e-04	197	46	4	7374_DN
Drug	Nafcillin sodium salt monohydrate [7177-50-6]; Up 200; 8.8uM; PC3; HT_HG-U133A	DVL3 KMT2A HNF1B MUC6	6.68e-04	197	46	4	3983_UP
Drug	troglitazone; Up 200; 10uM; MCF7; HT_HG-U133A	DVL3 MUC16 MAPK8 ZFHX4	6.68e-04	197	46	4	6991_UP
Drug	Clidinium bromide [3485-62-9]; Down 200; 9.2uM; PC3; HT_HG-U133A	DVL2 PCNX2 FGF5 EDC4	6.68e-04	197	46	4	4499_DN
Drug	Pindolol [13523-86-9]; Up 200; 16.2uM; PC3; HT_HG-U133A	FGF5 PACS1 LIMCH1 REV1	6.68e-04	197	46	4	2075_UP
Drug	Vincamine [1617-90-9]; Down 200; 11.2uM; MCF7; HT_HG-U133A	APC KMT2A MAPK8 ATXN7L1	6.68e-04	197	46	4	3865_DN
Drug	Chloropyramine hydrochloride [6170-42-9]; Up 200; 12.2uM; MCF7; HT_HG-U133A	NEDD9 FGF5 TBX3 LIMCH1	6.68e-04	197	46	4	3350_UP
Drug	Eucatropine hydrochloride [536-93-6]; Up 200; 12.2uM; HL60; HT_HG-U133A	FGF5 PACS1 HNF1B ZFHX4	6.68e-04	197	46	4	2556_UP
Drug	Quipazine dimaleate salt [4774-24-7]; Down 200; 9uM; MCF7; HT_HG-U133A	NEDD9 KMT2A LIMCH1 MAPK8	6.68e-04	197	46	4	2782_DN
Drug	Demecarium bromide [56-94-0]; Up 200; 5.6uM; MCF7; HT_HG-U133A	APC PACS1 MAPK8 ZFHX4	6.68e-04	197	46	4	2773_UP
Drug	PNU-0230031 [267429-39-0]; Up 200; 1uM; MCF7; HT_HG-U133A	PCNX2 KMT2A TBX3 ATXN7L1	6.68e-04	197	46	4	3632_UP
Drug	Ricinine [524-40-3]; Up 200; 24.4uM; MCF7; HT_HG-U133A	APC TBX3 HNF1B MAPK8	6.68e-04	197	46	4	6067_UP
Drug	Diazoxide [364-98-7]; Up 200; 17.4uM; MCF7; HT_HG-U133A	DVL2 PCNX2 NEDD9 PACS1	6.68e-04	197	46	4	7168_UP
Drug	Eucatropine hydrochloride [536-93-6]; Down 200; 12.2uM; MCF7; HT_HG-U133A	APC KMT2A LIMCH1 MAPK8	6.68e-04	197	46	4	3935_DN
Drug	tetraethylenepentamine pentahydrochloride; Up 200; 100uM; ssMCF7; HG-U133A	APC KMT2A FGF5 DSCAM	6.68e-04	197	46	4	498_UP
Drug	Bergenin monohydrate [477-90-7]; Down 200; 11.6uM; MCF7; HT_HG-U133A	NEDD9 LIMCH1 SSH1 DSCAM	6.68e-04	197	46	4	3467_DN
Drug	2-propylpentanoic acid; Down 200; 200uM; MCF7; HT_HG-U133A	APC PACS1 BRAF RPS6KA5	6.68e-04	197	46	4	6974_DN
Drug	NSC354462	MAPK8 BRAF	6.68e-04	19	46	2	CID000434668
Drug	Flucloxacillin sodium [1847-24-1]; Up 200; 8.4uM; PC3; HT_HG-U133A	APC KMT2A HNF1B ATXN7L1	6.80e-04	198	46	4	5102_UP
Drug	Canrenoic acid potassium salt [2181-04-6]; Up 200; 10uM; PC3; HT_HG-U133A	BNC1 FGF5 PACS1 MAPK8	6.80e-04	198	46	4	2065_UP
Drug	Bucladesine sodium salt [16980-89-5]; Down 200; 7.8uM; MCF7; HT_HG-U133A	LIMCH1 MAPK8 DSCAM RPS6KA5	6.80e-04	198	46	4	3483_DN
Drug	Amiloride hydrochloride dihydrate [17440-83-4]; Down 200; 13.2uM; PC3; HT_HG-U133A	NEDD9 APC PACS1 NRXN3	6.80e-04	198	46	4	3990_DN
Drug	Urapidil hydrochloride [64887-14-5]; Down 200; 9.4uM; PC3; HT_HG-U133A	APC FGF5 NRXN3 EDC4	6.80e-04	198	46	4	6696_DN
Drug	Seneciphylline [480-81-9]; Down 200; 12uM; HL60; HT_HG-U133A	NEDD9 APC MAPK8 ITGB1BP1	6.80e-04	198	46	4	2140_DN
Drug	AG-028671 [847803-03-6]; Down 200; 10uM; PC3; HT_HG-U133A	DVL2 PACS1 HNF1B NRXN3	6.80e-04	198	46	4	6557_DN
Drug	Piribedil hydrochloride [78213-63-5]; Up 200; 12uM; MCF7; HT_HG-U133A	DVL3 TBX3 HNF1B MAPK8	6.80e-04	198	46	4	5434_UP
Drug	alpha-estradiol; Up 200; 0.01uM; MCF7; HG-U133A	PCNX2 ZC3H7A HNF1B TRAK2	6.80e-04	198	46	4	762_UP
Drug	Diflorasone Diacetate [33564-31-7]; Up 200; 8uM; MCF7; HT_HG-U133A	DVL2 APC HNF1B RIMS1	6.80e-04	198	46	4	4158_UP
Drug	Pronethalol hydrochloride [51-02-5]; Up 200; 15uM; MCF7; HT_HG-U133A	PACS1 LIMCH1 BRAF MUC6	6.80e-04	198	46	4	7322_UP
Disease	Stomach Neoplasms	APC KMT2A TBX3 MAPK8 BRAF MUC6	6.60e-06	297	46	6	C0038356
Disease	Malignant neoplasm of stomach	APC KMT2A TBX3 MAPK8 BRAF MUC6	6.99e-06	300	46	6	C0024623
Disease	Drug habituation	PACS1 LIMCH1 NRXN3 DSCAM	3.15e-05	115	46	4	C0013170
Disease	Substance-Related Disorders	PACS1 LIMCH1 NRXN3 DSCAM	3.15e-05	115	46	4	C0236969
Disease	Drug abuse	PACS1 LIMCH1 NRXN3 DSCAM	3.15e-05	115	46	4	C0013146
Disease	Drug Use Disorders	PACS1 LIMCH1 NRXN3 DSCAM	3.15e-05	115	46	4	C0013222
Disease	Drug Dependence	PACS1 LIMCH1 NRXN3 DSCAM	3.15e-05	115	46	4	C1510472
Disease	Substance Dependence	PACS1 LIMCH1 NRXN3 DSCAM	3.15e-05	115	46	4	C0038580
Disease	Substance Use Disorders	PACS1 LIMCH1 NRXN3 DSCAM	3.15e-05	115	46	4	C0038586
Disease	Organic Mental Disorders, Substance-Induced	PACS1 LIMCH1 NRXN3 DSCAM	3.15e-05	115	46	4	C0029231
Disease	Prescription Drug Abuse	PACS1 LIMCH1 NRXN3 DSCAM	3.15e-05	115	46	4	C4316881
Disease	Substance abuse problem	PACS1 LIMCH1 NRXN3 DSCAM	3.26e-05	116	46	4	C0740858
Disease	triglyceride change measurement, response to long-chain n-3 PUFA dietary supplementation	IQCJ-SCHIP1 IQCJ	6.62e-05	8	46	2	EFO_0007681, EFO_0009308
Disease	total cholesterol measurement, response to escitalopram, response to citalopram	ARHGAP25 RIMS1	6.62e-05	8	46	2	EFO_0004574, EFO_0006329, EFO_0007871
Disease	Hereditary Diffuse Gastric Cancer	APC KMT2A TBX3 MAPK8 MUC6	9.16e-05	293	46	5	C1708349
Disease	colorectal cancer, colorectal adenoma	APC TBX3 TANC1 MUC22	9.33e-05	152	46	4	EFO_0005406, MONDO_0005575
Disease	thyroid gland papillary carcinoma (is_implicated_in)	BRAF SRGAP1	1.06e-04	10	46	2	DOID:3969 (is_implicated_in)
Disease	disease progression measurement	IQCJ-SCHIP1 HERC1 IQCJ	1.20e-04	61	46	3	EFO_0008336
Disease	nucleus accumbens volume change measurement	MUC16 DSCAM	1.30e-04	11	46	2	EFO_0021493
Disease	triacylglycerol 56:2 measurement	LIMCH1 ZFHX4	1.30e-04	11	46	2	EFO_0010429
Disease	cholangiocarcinoma (is_marker_for)	MUC16 MUC3A MUC6	1.38e-04	64	46	3	DOID:4947 (is_marker_for)
Disease	endometrial carcinoma (is_implicated_in)	APC BRAF	1.55e-04	12	46	2	DOID:2871 (is_implicated_in)
Disease	gallbladder cancer (is_implicated_in)	APC RICTOR	1.83e-04	13	46	2	DOID:3121 (is_implicated_in)
Disease	Benign neoplasm of stomach	APC BRAF	3.19e-04	17	46	2	C0153943
Disease	Neoplasm of uncertain or unknown behavior of stomach	APC BRAF	3.19e-04	17	46	2	C0496905
Disease	Carcinoma in situ of stomach	APC BRAF	3.19e-04	17	46	2	C0154060
Disease	Pancreatic carcinoma	APC BRAF	4.00e-04	19	46	2	C0235974
Disease	Neurodevelopmental Disorders	KMT2A RIMS1 DSCAM	4.17e-04	93	46	3	C1535926
Disease	Adenocarcinoma of large intestine	NEK4 APC BRAF	4.58e-04	96	46	3	C1319315
Disease	Stomach Carcinoma	APC BRAF	4.90e-04	21	46	2	C0699791
Disease	cholangiocarcinoma (is_implicated_in)	APC BRAF	5.38e-04	22	46	2	DOID:4947 (is_implicated_in)
Disease	Carcinoma of lung	RICTOR BRAF	5.89e-04	23	46	2	C0684249
Disease	coronary artery disease, factor VII measurement	FGF5 STAG1 MUC22	6.99e-04	111	46	3	EFO_0001645, EFO_0004619
Disease	factor VIII measurement, coronary artery disease	FGF5 STAG1 MUC22	7.36e-04	113	46	3	EFO_0001645, EFO_0004630
Disease	factor XI measurement, coronary artery disease	FGF5 STAG1 MUC22	7.75e-04	115	46	3	EFO_0001645, EFO_0004694
Disease	Colorectal cancer	APC BRAF	8.14e-04	27	46	2	cv:C0346629
Disease	COLORECTAL CANCER	APC BRAF	8.14e-04	27	46	2	114500
Disease	Neoplasm of the large intestine	APC BRAF	8.14e-04	27	46	2	cv:C0009404
Disease	colorectal adenocarcinoma (is_marker_for)	RICTOR MAPK8	8.14e-04	27	46	2	DOID:0050861 (is_marker_for)
Disease	von Willebrand factor measurement, coronary artery disease	FGF5 STAG1 MUC22	8.35e-04	118	46	3	EFO_0001645, EFO_0004629
Disease	response to aromatase inhibitor	MUC16 ATXN7L1	1.14e-03	32	46	2	GO_0061477
Disease	lower urinary tract symptom, benign prostatic hyperplasia	TBX3 HNF1B	1.14e-03	32	46	2	EFO_0000284, EFO_0008008
Disease	pelvic organ prolapse	DVL2 IQCJ-SCHIP1 IQCJ	1.26e-03	136	46	3	EFO_0004710
Disease	malignant epithelial tumor of ovary	HNF1B SRGAP1	1.37e-03	35	46	2	MONDO_0018364
Disease	interleukin 2 receptor antagonist measurement	PRR16 LIMCH1	1.37e-03	35	46	2	EFO_0008332
Disease	neurodegenerative disease (implicated_via_orthology)	DVL2 DVL3 TRAK2	1.51e-03	145	46	3	DOID:1289 (implicated_via_orthology)
Disease	cognitive function measurement	NEDD9 PRR16 IQCJ-SCHIP1 NRXN3 DSCAM IQCJ SRGAP1 REV1	1.53e-03	1434	46	8	EFO_0008354

Protein segments in the cluster

Peptide	Gene	Start	Entry
VSSSASMDTVTSSSS	BRAF	111	P15056
SMDTVTSSSSSSLSV	BRAF	116	P15056
SSTGSTRSNMSTSST	NEDD9	371	Q14511
TRSNMSTSSTSSKES	NEDD9	376	Q14511
TSLFSTIESTSMSTT	ADGRG4	401	Q8IZF6
TTASSSMGQTKSTSS	BAZ2B	191	Q9UIF8
LDLSTTSSMKSESSS	BNC1	856	Q01954
RSSSFSSITDSTMSL	DVL3	231	Q92997
TMSRFSSSTEQSSAS	DVL2	216	O14641
KMNSTTTTAVSASST	ATXN7L1	216	Q9ULK2
MTSVGKSRTTTESSA	CCNB3	1076	Q8WWL7
SSSSLTAVSAMSSTS	EDC4	626	Q6P2E9
KLSSSVSMNTFSDSS	IQCJ	81	Q1A5X6
SISQESSTSSFSSMS	ANKRD27	641	Q96NW4
SSTSSFSSMSASSRQ	ANKRD27	646	Q96NW4
TSSKSLSMGNSTHTS	MUC16	1881	Q8WXI7
SSAMTSTSLASKLTT	MUC16	3001	Q8WXI7
ATTSTAQSTTRTTMT	MUC6	1316	Q6W4X9
TTMASSTTSTAGSEK	MUC22	151	E2RYF6
STTSTAGSEKTMASS	MUC22	156	E2RYF6
STADSKVITASSMSS	MUC22	241	E2RYF6
AMGSETTTNSTTSSE	MUC22	371	E2RYF6
SSTTSFMSSSLEDTT	HERC1	2641	Q15751
REMQVSSSSTTTSES	PCNX2	741	A6NKB5
SSSSSVNDVSSMSTD	MAPK8	391	P45983
SSITSTNTVTSMTTT	MUC3A	261	Q02505
TDLTSTFTVSSSSAM	MUC3A	466	Q02505
SSVTSTNTVTSMTTT	MUC3A	636	Q02505
TSTFTVSSSSAMSTS	MUC3A	1221	Q02505
SVSSSRSSEMSSSKD	NEK4	596	P51957
TTMATTTTRKNRSTA	NRXN3	1291	Q9Y4C0
MKKTSTSTETRSSSS	RPS6KA5	746	O75582
NTDTTTSGISSMSSS	RICTOR	1221	Q6R327
SSSSSSTSTSMAVAV	PACS1	66	Q6VY07
SRTSSASRLSSTSFM	RIMS1	1351	Q86UR5
SRQSSSSAMSSSSAS	FGF5	46	P12034
STVTMSTSSVTSSSN	HECTD1	1606	Q9ULT8
TSETSTMRTTDSTSG	CEP126	386	Q9P2H0
SQHSSQMSSDSSRSS	KMT2A	466	Q03164
SSSSQSSEISTKSKS	ITGB1BP1	11	O14713
SSSADQLSTSSSMTE	LIMCH1	836	Q9UPQ0
DTSSISTLTNMSSSK	HNF1B	536	P35680
RARSSMVSTESASST	DSCAM	1796	O60469
RSTSSSSDTMSTFKP	SRGAP1	1026	Q7Z6B7
ELNSRSSTLSSSSMS	TBX3	691	O15119
TTMATTTTRKNRSTA	NRXN3	286	Q9HDB5
MTDSSKTDTLNSSSS	PRR16	71	Q569H4
SSIKMSSSTSSLTSS	TANC1	1671	Q9C0D5
KLSSSVSMNTFSDSS	IQCJ-SCHIP1	81	B3KU38
SSMSSNLTRSSSSDS	SSH1	926	Q8WYL5
SKTEHMSSSSENTST	APC	1206	P25054
TNRRDSTTTFSSTMS	TRAK2	726	O60296
TSVSLSHSSSESSKM	ZFHX4	421	Q86UP3
TSRNSVMSPSSSKST	SRRM5	51	B3KS81
SSTKSTSSVSTFSKA	REV1	321	Q9UBZ9
SRTDSFSSMTSDSDT	ARHGAP25	391	P42331
MSVNSGSSSSKTSSV	STAG1	1061	Q8WVM7
SFSMSESKRDLSTST	ZC3H7A	361	Q8IWR0