Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncopper ion transmembrane transporter activity

SLC31A1 ATP7A

2.39e-058192GO:0005375
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

SLC31A1 ABCC8 SCN1A RYR2 ATP7A

5.95e-05465195GO:0046873
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

SLC31A1 ABCC8 SCN1A RYR2 ATP7A

2.42e-04627195GO:0022890
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

SLC31A1 ABCC8 SCN1A RYR2 ATP7A

3.16e-04664195GO:0008324
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

SLC31A1 ABCC8 SCN1A RYR2 ATP7A

5.80e-04758195GO:0015318
GeneOntologyMolecularFunctiontransmembrane transporter activity

SLC31A1 ABCC8 SCN1A RYR2 ATP7A SLC35B1

5.85e-041180196GO:0022857
GeneOntologyMolecularFunctionATP hydrolysis activity

SMARCA4 NAV1 ABCC8 ATP7A

6.99e-04441194GO:0016887
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

SLC31A1 ABCC8 SCN1A RYR2 ATP7A

7.13e-04793195GO:0015075
GeneOntologyMolecularFunctiontransition metal ion transmembrane transporter activity

SLC31A1 ATP7A

7.92e-0444192GO:0046915
GeneOntologyMolecularFunctiontransporter activity

SLC31A1 ABCC8 SCN1A RYR2 ATP7A SLC35B1

9.35e-041289196GO:0005215
GeneOntologyMolecularFunctionATPase-coupled monoatomic cation transmembrane transporter activity

ABCC8 ATP7A

1.57e-0362192GO:0019829
GeneOntologyMolecularFunctionATP-dependent activity

SMARCA4 NAV1 ABCC8 ATP7A

2.37e-03614194GO:0140657
GeneOntologyMolecularFunctioncopper ion binding

SLC31A1 ATP7A

2.47e-0378192GO:0005507
GeneOntologyMolecularFunctiongated channel activity

ABCC8 SCN1A RYR2

3.68e-03334193GO:0022836
GeneOntologyMolecularFunctionmonoatomic cation channel activity

ABCC8 SCN1A RYR2

3.97e-03343193GO:0005261
GeneOntologyMolecularFunctionATPase-coupled transmembrane transporter activity

ABCC8 ATP7A

4.75e-03109192GO:0042626
GeneOntologyMolecularFunctionribonucleoside triphosphate phosphatase activity

SMARCA4 NAV1 ABCC8 ATP7A

5.48e-03775194GO:0017111
GeneOntologyMolecularFunctionpyrophosphatase activity

SMARCA4 NAV1 ABCC8 ATP7A

7.24e-03839194GO:0016462
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides

SMARCA4 NAV1 ABCC8 ATP7A

7.27e-03840194GO:0016817
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

SMARCA4 NAV1 ABCC8 ATP7A

7.27e-03840194GO:0016818
GeneOntologyMolecularFunctionligand-gated monoatomic cation channel activity

ABCC8 RYR2

7.72e-03140192GO:0099094
GeneOntologyMolecularFunctionmonoatomic ion channel activity

ABCC8 SCN1A RYR2

8.89e-03459193GO:0005216
GeneOntologyMolecularFunctionactive transmembrane transporter activity

ABCC8 ATP7A SLC35B1

9.87e-03477193GO:0022804
GeneOntologyMolecularFunctionchromatin DNA binding

SMARCA4 ZIC2

1.08e-02167192GO:0031490
GeneOntologyMolecularFunctionprimary active transmembrane transporter activity

ABCC8 ATP7A

1.22e-02178192GO:0015399
GeneOntologyMolecularFunctionvoltage-gated monoatomic ion channel activity

ABCC8 SCN1A

1.28e-02182192GO:0005244
GeneOntologyMolecularFunctionchannel activity

ABCC8 SCN1A RYR2

1.28e-02525193GO:0015267
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

ABCC8 SCN1A RYR2

1.29e-02526193GO:0022803
GeneOntologyMolecularFunctionvoltage-gated channel activity

ABCC8 SCN1A

1.30e-02184192GO:0022832
GeneOntologyMolecularFunctionligand-gated monoatomic ion channel activity

ABCC8 RYR2

1.43e-02193192GO:0015276
GeneOntologyMolecularFunctionligand-gated channel activity

ABCC8 RYR2

1.48e-02197192GO:0022834
GeneOntologyBiologicalProcesscopper ion import

SLC31A1 ATP7A

2.88e-059192GO:0015677
GeneOntologyBiologicalProcesscopper ion transmembrane transport

SLC31A1 ATP7A

2.88e-059192GO:0035434
GeneOntologyBiologicalProcesspositive regulation of monoatomic ion transport

CTSS ABCC8 RYR2 ATP7A

9.00e-05266194GO:0043270
GeneOntologyBiologicalProcesspositive regulation of ion transmembrane transporter activity

CTSS RYR2 ATP7A

9.25e-0597193GO:0032414
GeneOntologyBiologicalProcesspositive regulation of transporter activity

CTSS RYR2 ATP7A

1.24e-04107193GO:0032411
GeneOntologyBiologicalProcessmonoatomic cation transmembrane transport

SLC31A1 CTSS ABCC8 SCN1A RYR2 ATP7A

1.45e-04942196GO:0098655
GeneOntologyBiologicalProcesstransition metal ion transport

SLC31A1 RYR2 ATP7A

1.46e-04113193GO:0000041
GeneOntologyBiologicalProcesscopper ion transport

SLC31A1 ATP7A

1.51e-0420192GO:0006825
GeneOntologyBiologicalProcessintracellular copper ion homeostasis

SLC31A1 ATP7A

1.51e-0420192GO:0006878
GeneOntologyBiologicalProcesscopper ion homeostasis

SLC31A1 ATP7A

2.01e-0423192GO:0055070
GeneOntologyBiologicalProcessmonoatomic ion transmembrane transport

SLC31A1 CTSS ABCC8 SCN1A RYR2 ATP7A

3.63e-041115196GO:0034220
GeneOntologyBiologicalProcessmonoatomic cation transport

SLC31A1 CTSS ABCC8 SCN1A RYR2 ATP7A

4.43e-041157196GO:0006812
GeneOntologyBiologicalProcesspositive regulation of monoatomic ion transmembrane transport

CTSS RYR2 ATP7A

6.89e-04192193GO:0034767
GeneOntologyBiologicalProcessaction potential

ABCC8 SCN1A RYR2

7.87e-04201193GO:0001508
GeneOntologyBiologicalProcessepidermis morphogenesis

SMARCA4 ATP7A

8.12e-0446192GO:0048730
GeneOntologyBiologicalProcessintracellular chemical homeostasis

SMARCA4 SLC31A1 ABCC8 RYR2 ATP7A

9.17e-04866195GO:0055082
GeneOntologyBiologicalProcesshindlimb morphogenesis

SMARCA4 ATP7A

9.21e-0449192GO:0035137
GeneOntologyBiologicalProcessresponse to pH

CTSS ABCC8

9.21e-0449192GO:0009268
GeneOntologyBiologicalProcessmonoatomic ion transport

SLC31A1 CTSS ABCC8 SCN1A RYR2 ATP7A

1.10e-031374196GO:0006811
GeneOntologyBiologicalProcessinorganic cation transmembrane transport

SLC31A1 ABCC8 SCN1A RYR2 ATP7A

1.22e-03922195GO:0098662
GeneOntologyBiologicalProcesstube development

SMARCA4 SLC31A1 ABCC8 RYR2 ZIC2 ATP7A

1.23e-031402196GO:0035295
GeneOntologyBiologicalProcessresponse to zinc ion

ABCC8 ATP7A

1.42e-0361192GO:0010043
GeneOntologyBiologicalProcesscardiac muscle cell action potential involved in contraction

SCN1A RYR2

1.47e-0362192GO:0086002
GeneOntologyBiologicalProcessregulation of monoatomic ion transmembrane transporter activity

CTSS RYR2 ATP7A

1.58e-03256193GO:0032412
GeneOntologyBiologicalProcesscellular homeostasis

SMARCA4 SLC31A1 ABCC8 RYR2 ATP7A

1.60e-03981195GO:0019725
GeneOntologyBiologicalProcessregulation of monoatomic ion transport

CTSS ABCC8 RYR2 ATP7A

1.68e-03577194GO:0043269
GeneOntologyBiologicalProcessmetal ion transport

SLC31A1 ABCC8 SCN1A RYR2 ATP7A

1.74e-031000195GO:0030001
GeneOntologyBiologicalProcessregulation of transmembrane transporter activity

CTSS RYR2 ATP7A

1.76e-03266193GO:0022898
GeneOntologyBiologicalProcessinorganic ion transmembrane transport

SLC31A1 ABCC8 SCN1A RYR2 ATP7A

1.88e-031017195GO:0098660
GeneOntologyBiologicalProcesspositive regulation of transmembrane transport

CTSS RYR2 ATP7A

1.90e-03273193GO:0034764
GeneOntologyCellularComponentaxon initial segment

NAV1 SCN1A

3.13e-0429192GO:0043194
MousePhenodecreased paired-pulse ratio

SCN1A RYR2

8.34e-064172MP:0014253
MousePhenodecreased brain copper level

SLC31A1 ATP7A

8.34e-064172MP:0011215
MousePhenoabnormal brain copper level

SLC31A1 ATP7A

1.39e-055172MP:0011213
MousePhenodecreased copper level

SLC31A1 ATP7A

1.39e-055172MP:0014540
MousePhenoabnormal paired-pulse ratio

SCN1A RYR2

2.91e-057172MP:0014252
MousePhenoventricular fibrillation

SCN1A RYR2

2.91e-057172MP:0006110
MousePhenoabnormal copper level

SLC31A1 ATP7A

6.23e-0510172MP:0003952
MousePhenoabnormal copper homeostasis

SLC31A1 ATP7A

7.61e-0511172MP:0003951
MousePhenolethality throughout fetal growth and development, incomplete penetrance

TLE3 SCN1A RYR2 ATP7A

9.74e-05208174MP:0011109
MousePhenofibrillation

SCN1A RYR2

1.26e-0414172MP:0006109
MousePhenodecreased brain size

NAV1 TLE3 SCN1A ZIC2

3.72e-04295174MP:0000774
MousePhenoventricular premature beat

SCN1A RYR2

4.11e-0425172MP:0009732
MousePhenotonic seizures

SCN1A ATP7A

4.11e-0425172MP:0002826
MousePhenodelayed neural tube closure

SLC31A1 ZIC2

6.34e-0431172MP:0002621
MousePhenoconvulsive seizures

SCN1A RYR2 ATP7A

7.81e-04153173MP:0000947
MousePhenoabnormal brain size

NAV1 TLE3 SCN1A ZIC2

9.19e-04375174MP:0000771
MousePhenoabnormal blood vessel morphology

MIPOL1 SMARCA4 CTSS ZNF280C ZIC2 ATP7A ADGRL4

1.06e-031472177MP:0001614
MousePhenoembryonic lethality during organogenesis, complete penetrance

SMARCA4 SLC31A1 RYR2 ZIC2 ATP7A

1.16e-03700175MP:0011098
MousePhenolethality throughout fetal growth and development

TLE3 SCN1A RYR2 ATP7A

1.59e-03435174MP:0006208
MousePhenopostnatal lethality, complete penetrance

SCN1A RYR2 ZIC2 ATP7A

1.73e-03445174MP:0011085
MousePhenoabnormal cardiovascular development

SMARCA4 CTSS RYR2 ATP7A ADGRL4

2.13e-03802175MP:0002925
MousePhenoabnormal spleen size

NAV1 CTSS TLE3 RYR2 ZIC2 ATP7A

2.16e-031203176MP:0002224
MousePhenotonic-clonic seizures

SCN1A RYR2

2.52e-0362172MP:0003997
MousePhenoabnormal blood circulation

SLC31A1 ZC3H4 ZIC2 ATP7A ADGRL4

2.68e-03845175MP:0002128
MousePhenoabnormal brain wave pattern

SCN1A RYR2

2.68e-0364172MP:0004994
DomainIon_trans_dom

SCN1A RYR2

5.90e-03114192IPR005821
DomainIon_trans

SCN1A RYR2

5.90e-03114192PF00520
DomainAAA+_ATPase

NAV1 ABCC8

9.26e-03144192IPR003593
DomainAAA

NAV1 ABCC8

9.26e-03144192SM00382
Pubmed

Decreased Expression of the Slc31a1 Gene and Cytoplasmic Relocalization of Membrane CTR1 Protein in Renal Epithelial Cells: A Potent Protective Mechanism against Copper Nephrotoxicity in a Mouse Model of Menkes Disease.

SLC31A1 ATP7A

9.42e-07320236232742
Pubmed

Elesclomol alleviates Menkes pathology and mortality by escorting Cu to cuproenzymes in mice.

SLC31A1 ATP7A

9.42e-07320232381719
Pubmed

Intestinal expression of metal transporters in Wilson's disease.

SLC31A1 ATP7A

9.42e-07320223963605
Pubmed

Impaired copper transport in schizophrenia results in a copper-deficient brain state: A new side to the dysbindin story.

SLC31A1 ATP7A

9.42e-07320230230404
Pubmed

Upregulated copper transporters in hypoxia-induced pulmonary hypertension.

SLC31A1 ATP7A

1.88e-06420224614111
Pubmed

Dual role of LRRC8A-containing transporters on cisplatin resistance in human ovarian cancer cells.

SLC31A1 ATP7A

1.88e-06420227112899
Pubmed

Expression of copper trafficking genes in the mouse brain.

SLC31A1 ATP7A

4.71e-0662029831461
Pubmed

The mitochondrial metallochaperone SCO1 maintains CTR1 at the plasma membrane to preserve copper homeostasis in the murine heart.

SLC31A1 ATP7A

6.55e-052120228973536
Pubmed

Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development.

ABCC8 SCN1A RYR2

6.78e-0513920316985003
Pubmed

Time-sequenced transcriptomes of developing distal mouse limb buds: A comparative tissue layer analysis.

TLE3 ZIC2

7.21e-052220234254395
Pubmed

A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex.

ZC3H4 ARHGAP21 TLE3 ZNF280C

1.37e-0447220438943005
Pubmed

Combinatorial CRISPR screen identifies fitness effects of gene paralogues.

SMARCA4 NAV1 ZC3H4

1.60e-0418620333637726
Pubmed

Gfi1b regulates the level of Wnt/β-catenin signaling in hematopoietic stem cells and megakaryocytes.

SMARCA4 TLE3

1.74e-043420230894540
Pubmed

Pioneering function of Isl1 in the epigenetic control of cardiomyocyte cell fate.

SMARCA4 RYR2

1.74e-043420231024170
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

SMARCA4 NAV1 ZC3H4 ARHGAP21 ZIC2

1.77e-0496320528671696
Pubmed

Identification and Functional Characterization of a Novel Androgen Receptor Coregulator, EAP1.

SMARCA4 TLE3

2.42e-044020234585037
Pubmed

Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.

SMARCA4 ZC3H4 TLE3

4.68e-0426820333640491
Pubmed

Mapping the Ku Interactome Using Proximity-Dependent Biotin Identification in Human Cells.

SMARCA4 ZC3H4 ZNF280C

5.48e-0428320330585729
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

NAV1 CTSS CREB5 RYR2

1.30e-0618620423b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCellChildren_(3_yrs)-Immune-dendritic_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

NAV1 ADAM28 ABCC8

4.13e-051522030769857f25da2e6169420818e61d65e33b7277b1
ToppCelldroplet-Marrow-nan-3m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CTSS TLE3 ATP7A

6.28e-05175203cf53a15bfb37b6019e7052ffdf594a9ac040900e
ToppCellsaliva-Severe-critical_progression_d28-40|saliva / Compartment, severity and other cell annotations on 10x 3' data (130k)

CTSS CREB5 TLE3

7.53e-051862030095560ca776b01aa473ad4d6015ed78fc93ff51
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NAV1 CREB5 ADGRL4

7.77e-05188203c2c51c6526defe2600302901159b8abbb58d7595
ToppCellwk_15-18-Endothelial-Lymph_endothelial-SCG3+_lymphatic_endothelial|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

NAV1 ZIC2 ADGRL4

7.89e-05189203f0418851ad4042c4cd87c8729e4f0d43bdf8fccb
ToppCellhuman_hepatoblastoma-Endothelial_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

NAV1 CREB5 ADGRL4

8.02e-051902038d6ef93d69e96cd6921816d152bea3b0710cf147
ToppCellCOVID-19-Heart|COVID-19 / Disease (COVID-19 only), tissue and cell type

NAV1 CREB5 RYR2

8.02e-05190203918ad5037881212008f9f69d5df5da91fd01422c
ToppCellhuman_hepatoblastoma-Endothelial_cells|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)

NAV1 CREB5 ADGRL4

8.27e-05192203e09f609fed033a25baacaf4a07bbbae1076da366
ToppCellChildren_(3_yrs)-Immune-monocyte-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

ADAM28 CTSS CREB5

8.40e-0519320358e1930a1d80ad3729ab9604ac8ebf7308232a3d
ToppCellnucseq-Endothelial-Endothelial_Vascular-Endothelial_capillary-CAP1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

NAV1 ABCC8 ADGRL4

8.40e-05193203ad3f4fcc8e2816d696cbcde744dc16500e51ccac
ToppCellmild-Myeloid-Neutrophils_1|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

CTSS CREB5 TLE3

8.53e-05194203ccd911ce3251cd1c60f1fb2ce00650fbe7a379bb
ToppCellIIH-mDC2-|IIH / Condition, Cell_class and T cell subcluster

ADAM28 CTSS CREB5

8.66e-05195203ed4fcd51d523d960bf3650bf284d400007e55714
ToppCellChildren_(3_yrs)-Immune-monocyte-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

NAV1 ADAM28 CREB5

8.66e-0519520381a28289eda1a8a1a31b7357106f64ac5000e172
ToppCellIIH-mDC2|IIH / Condition, Cell_class and T cell subcluster

ADAM28 CTSS CREB5

8.66e-051952034146912b69041cc1505ddba4125c8e10e0125329
ToppCellmyeloid-CD14+_Monocyte|myeloid / Lineage and Cell class

CTSS CREB5 TLE3

8.66e-0519520360fab0c24c827567fb42bbd7eb165bf45178c198
ToppCellChildren_(3_yrs)-Immune-monocyte|Children_(3_yrs) / Lineage, Cell type, age group and donor

ADAM28 CTSS CREB5

8.79e-05196203cacd69be72e6167814f7adea7c5fa114f3103bbb
ToppCellAdult-Immune-monocyte|Adult / Lineage, Cell type, age group and donor

ADAM28 CTSS CREB5

8.79e-051962033ef193c5180de3137daf886492e74fc574bc9767
ToppCellMS-mDC2|MS / Condition, Cell_class and T cell subcluster

ADAM28 CTSS CREB5

8.79e-051962034707e4a911c6ea032f69aa1e431d5f4260bda011
ToppCellMS-mDC2-|MS / Condition, Cell_class and T cell subcluster

ADAM28 CTSS CREB5

8.79e-05196203064029b1376fa673f25f80596609be86ce0409a9
ToppCellmild-Myeloid-Neutrophils_4|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

CTSS CREB5 TLE3

8.79e-05196203f8c98cded5550843322b1711e1a57c7e88cae861
ToppCellAdult-Immune-monocyte-D122|Adult / Lineage, Cell type, age group and donor

ADAM28 CTSS CREB5

8.79e-0519620316b0acb6157534938ca83d4e909471e33a7d3c52
ToppCellCOVID-19-lung-Capillary_1|COVID-19 / Disease (COVID-19 only), tissue and cell type

NAV1 ABCC8 ADGRL4

8.79e-05196203ac28e9be288af6f00a841aea4ce4b99aed6b4505
ToppCellMonocytes-cDCs|World / Immune cells in Kidney/Urine in Lupus Nephritis

NAV1 ADAM28 CREB5

8.92e-051972033388c104af4c6a05988e102627e0c5e34d9dcc45
ToppCelldistal-Hematologic-IGSF21+_Dendritic-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ADAM28 CTSS CREB5

8.92e-05197203e77c91f5a1f5a292eda41abf3b1e31180f2c61e1
ToppCellCOVID-19-lung-Capillary_1|lung / Disease (COVID-19 only), tissue and cell type

NAV1 ABCC8 ADGRL4

8.92e-051972037e86ff9dafcbaaa7464d61484dd48bfeb7eae6e4
ToppCellBronchial-NucSeq-Immune_Myeloid-Dendritic_cell|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

NAV1 ADAM28 CTSS

8.92e-05197203e0fc098bfb5a8b7824ae339f3adda30f78360d0b
ToppCellPBMC-Mild-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_4|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CTSS CREB5 TLE3

9.06e-0519820306201b34d3e38f22c93b759511f7b376504bac06
ToppCellPBMC-Mild-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_4|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CTSS CREB5 TLE3

9.06e-051982031ca91559fef231896e16180f5e050155c38f7cfa
ToppCellImmune-monocyte|World / Lineage, Cell type, age group and donor

ADAM28 CTSS CREB5

9.06e-05198203d3622da252fd580f1dc5c7478a8e23df5ec083cf
ToppCellCOVID-19_Mild-Classical_Monocyte|COVID-19_Mild / Disease condition and Cell class

CTSS CREB5 TLE3

9.06e-0519820330ada3de865b6fb2b14196a1cbfd4740c6a57ce3
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NAV1 ABCC8 SCN1A

9.19e-0519920319a97e27a4758e794ce7246d295e112b47931a48
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NAV1 ABCC8 SCN1A

9.19e-05199203333056c2abe9724efeab542c0365fcfe4eff8f18
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NAV1 ABCC8 SCN1A

9.19e-05199203e60ecbb8fa7bcd3e2ce7d78f6efb2cfd1fd77698
ToppCell3'_v3-Lung-Myeloid_Monocytic|Lung / Manually curated celltypes from each tissue

CTSS CREB5 TLE3

9.19e-051992033e14f9a62d6414add8d5f681be184b4625001838
ToppCellTracheal-NucSeq-Endothelial-Endothelia_vascular-VE_pulmonary_venous|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ABCC8 ZNF280C ADGRL4

9.19e-05199203079931e7196719f22a89cfad82f452ec67219ee5
ToppCellNon-neuronal-Postmitotic|World / Primary Cells by Cluster

ADAM28 CTSS ADGRL4

9.19e-05199203f6a9119ad32d9f0173c432de353b5315a7cf01ad
ToppCell3'_v3-Lung-Myeloid_Monocytic-Classical_monocytes|Lung / Manually curated celltypes from each tissue

CTSS CREB5 TLE3

9.19e-05199203bfd0d171ea6bb7abd5cdfeac22608cc190aaa2be
ToppCellmild-Classical_Monocyte|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

CTSS CREB5 TLE3

9.33e-05200203c8b80d4e7f70c66cbbdd0665821bcd5db69c7d35
ToppCellsevere-Classical_Monocyte|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

CTSS CREB5 TLE3

9.33e-05200203f46689940fdea500ce2457eec412dd2c46705819
ToppCellmild-Classical_Monocyte|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

CTSS CREB5 TLE3

9.33e-052002037beafb86fd77b022bd0549c8642a630937e364c3
ToppCellsevere-HLA-DR-_S100A+_Monocyte|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

CTSS CREB5 TLE3

9.33e-05200203a5eb50cbf3e94f0b3aa0fbef888989a11cffea37
ToppCellBrain_organoid-organoid_Tanaka_cellReport-10w-Neuronal-Neuron|10w / Sample Type, Dataset, Time_group, and Cell type.

NAV1 ARHGAP21 ZIC2

9.33e-05200203332905a686356cd1e024d40679be98e9d8b1b5e8
ToppCellsevere-Classical_Monocyte|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

CTSS CREB5 TLE3

9.33e-05200203ce03be0ccfc22eb923302a2ad73b39752e888270
ToppCellParenchymal-NucSeq-Immune_Myeloid-Monocytic-Monocyte_CD14|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ADAM28 CTSS CREB5

9.33e-05200203b4277b6faa69f20974696c7c422311f5c89e3663
ToppCelldroplet-Heart-HEART_(ALL_4:4:4:1:1)-30m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAM28 CTSS

9.79e-04104202a3d061170fe49d023ac31dbaeb2b5d2347988078
ToppCelldroplet-Heart-HEART_(ALL_4:4:4:1:1)|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAM28 CTSS

9.79e-04104202fdf4599de8cd4ccf1bd7ede4e7af63d69c108b43
ToppCelldroplet-Heart-nan-24m-Endothelial-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAM28 ADGRL4

1.19e-03115202e11128262ba1e2a7053b1b6c039f1aab37d2ce27
ToppCellControl-Endothelial-Endothelial-Activated_Gen_Cap|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NAV1 CREB5

1.32e-03121202a5962d1c476e6966870832b72d511607e047248b
ToppCellTCGA-Peripheral_Nervous_System-Primary_Tumor-Paraganglioma-Paraganglioma-3|TCGA-Peripheral_Nervous_System / Sample_Type by Project: Shred V9

MIPOL1 SLC31A1

1.64e-03135202ac20133d4a36f48338b45bffb13e842cb66f83ad
ToppCellLA-15._Ventricular_Cardiomyocyte_III|World / Chamber and Cluster_Paper

CREB5 RYR2

1.74e-031392029e2a84d5ed7232b70eadbba754d9ca13f2d50fe9
ToppCellfacs-Thymus-nan-3m-Epithelial-epithelial_cell_of_thymus|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP21 ZIC2

1.76e-03140202115bd770a9d5e6f007a9aa0eadf5dba46d500107
ToppCellfacs-Thymus-nan-3m-Epithelial|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP21 ZIC2

1.76e-0314020222d126e80bf7d9c0ca6ec686b5cc66fa584a1ab6
ToppCellfacs-Thymus-nan-3m-Epithelial-TECs|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP21 ZIC2

1.76e-0314020262d1ef8cb78618ed89cac7ec89d7f54de06a90c7
ToppCellBLOOD--(3)_MNP-(3)_Classical_Mono-1|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

CTSS CREB5

1.81e-03142202395f80e99be4a0ef07fb9d65c74399e7e67c9a8d
ToppCellfacs-Diaphragm-Limb_Muscle-18m-Myeloid-nan|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZC3H4 CTSS

1.91e-0314620269cbe8d4772f8e46a5e1a1cdca0e370308a97b4f
ToppCellCOVID-19-kidney-Technical/muscle_(PCT)|kidney / Disease (COVID-19 only), tissue and cell type

SCN1A RYR2

1.91e-03146202c55f1bdb6ac43b4118cb27ea7c879527e1afcbab
ToppCellBAL-Mild-Myeloid-cDC-cDC-cDC_4|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

NAV1 ADAM28

1.99e-03149202a85a051e0d82430160967e72fa04b55f43e84513
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

MIPOL1 SCN1A

1.99e-03149202c5eedb54ef2e0f131aa6730612c921bc19479632
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_granulocytic|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

MIPOL1 SCN1A

1.99e-03149202a22417286de8606f0cc94f86b70bce17aeefb9c2
ToppCellBAL-Mild-Myeloid-cDC-cDC-cDC_4|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

NAV1 ADAM28

2.02e-031502027a381f5ae94eba5eb60dcbf83416b4eb18c279ea
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC8 RYR2

2.07e-031522020cb5f4dfae04e3f4eba502bbf229007d5fa3884d
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC8 RYR2

2.07e-03152202ee329249a034a969a16b26a224aa04249d67382d
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC8 RYR2

2.07e-03152202bd1f36b436d8ab7dd8420f595b97d851eab31a38
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC8 RYR2

2.07e-03152202ba89ffb5a8bb33c188f854f54b39123b6d73496a
ToppCellMyeloid-F|World / shred on cell class and cell subclass (v4)

SLC31A1 CTSS

2.12e-031542026d53eec4aefe54836bbfd314f28f5e9a24c2d833
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell_prolif|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NAV1 ADGRL4

2.12e-03154202e51a5114f0ec38f997f5b8bbf3a7770f98595474
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC8 SCN1A

2.12e-03154202c0fe767fc9ab45b2dfa71171f2a673a4a8decbaf
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal--glomerular_mesenchymal_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC8 SCN1A

2.12e-031542023211f003f4d1735c7cab9b6cc68af3e0bbfba35e
ToppCellfacs-Heart-RV-24m-Myeloid|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CTSS ZIC2

2.12e-03154202709e7eedec11e675c6bbd55940f91dea5f715f4c
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal--glomerular_mesenchymal_cell-Renin-positive_Juxtaglomerular_Granular_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC8 SCN1A

2.12e-031542024c2a7590791c2255b15dab82c3622f71f9ffd949
ToppCelldroplet-Liver-Npc-21m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP21 CTSS

2.15e-031552025d600e159738231d0607ea1a1ebd8510fc241b36
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC-OPC-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NAV1 SCN1A

2.15e-0315520277fdae85d36efb776db977eb424b32487ef222e4
ToppCelldroplet-Kidney-KIDNEY-30m-Myeloid-nan|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CTSS CREB5

2.18e-031562026e60e860603a7e8194f437a574ff8e887f6083b8
ToppCellCOVID-19-Myeloid-Dendritic_cells|COVID-19 / group, cell type (main and fine annotations)

ADAM28 CTSS

2.18e-03156202a07a9096799e4ba663841c70035b4b32c1fda4f9
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-Degenerative_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NAV1 ADGRL4

2.18e-03156202ea9223bb6450b22df11efa1705ab72dab005244a
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-Degenerative_Endothelial_Cell-Degenerative_Peritubular_Capilary_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NAV1 ADGRL4

2.18e-03156202586b5509074c4cc359e9e31a968c2ded71c994ca
ToppCellfacs-Heart-RA-24m-Mesenchymal-atrial_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC8 RYR2

2.21e-031572029021900d9b1a71210c9c414a9d165eaf399eb607
ToppCellfacs-Heart-RA-24m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC8 RYR2

2.21e-03157202c8c627ca181856cd31dba4cf073c2be659a49dc1
ToppCellPBMC-Severe-Myeloid-cDC-cDC-cDC_1|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

NAV1 ADAM28

2.21e-03157202e9d0300361b06aec3c216f8af15f09e14b12a4da
ToppCelldroplet-Kidney-nan-18m-Myeloid-nan|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CTSS CREB5

2.21e-03157202eb64a4e89843895d16015c7d51805f164ed7ea5b
ToppCellLPS-IL1RA-Stromal_mesenchymal-Fibroblasts-Pericyte_2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TLE3 RYR2

2.23e-031582027f5426585d0d299d2b48e5fcb349950feffdef33
ToppCellPBMC-Severe-Myeloid-cDC-cDC-cDC_1|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

NAV1 ADAM28

2.23e-03158202e9657d8960d499832f9f9b45b5a6f4388551b7e1
ToppCellfacs-Liver-Liver_non-hepato/SCs-18m-Myeloid-myeloid_leukocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CTSS SCN1A

2.23e-03158202bd37d567754b660bfff7aef81cb307a384ec20a0
ToppCellBAL-Mild-Myeloid-cDC-cDC-cDC_0|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ADAM28 CREB5

2.26e-03159202ded4e3626a62fb6334403b7213b467fb7e8131c3
ToppCellBAL-Mild-Myeloid-cDC-cDC-cDC_0|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

ADAM28 CREB5

2.26e-031592022f6c60ddff2208a68146f9786143d9aefd528840
ToppCellPND07-Epithelial-Epithelial_Airway-Neurosecretory-Secretory|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADAM28 SERPINA7

2.29e-03160202028b5261a1da832d52f66fb620db83e5fbbd874a
ToppCelldroplet-Kidney-nan-18m-Myeloid-CD45____macrophage|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CTSS CREB5

2.29e-03160202d18c4cc99a31481dd0ee8af9299695d5f6857b42
ToppCellCOVID-19-kidney-Epithelial_(EC)|kidney / Disease (COVID-19 only), tissue and cell type

NAV1 ADGRL4

2.29e-031602020d4880f85565d8c540c94a8f8109147b3029279a
ToppCellPND07-Epithelial-Epithelial_Airway-Neurosecretory-Secretory-Secretory_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADAM28 SERPINA7

2.29e-031602021f4ee446436726c3d373f56d87dd80b6a12e8b9e
ToppCellAdult-Endothelial-endothelial_cell_of_vein-D122|Adult / Lineage, Cell type, age group and donor

ABCC8 ADGRL4

2.29e-031602020cfe130606af433b2aa90e0a20b6c44659dd6fd4
ToppCelldroplet-Kidney-nan-18m-Myeloid|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CTSS CREB5

2.29e-03160202a707a4ad9fbedcca227f76b49f1393e88101c2fb
ToppCelldroplet-Liver-Npc-21m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP21 CTSS

2.29e-0316020285205dc68369d3e04df3460c1f3861ee2dc242a9
ToppCelldroplet-Kidney-nan-18m-Myeloid-macrophage|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CTSS CREB5

2.29e-0316020273b604cbdcd9e8f0f317964abc632abee314a557
ToppCellChildren_(3_yrs)-Immune-dendritic_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

NAV1 ADAM28

2.32e-03161202cd41abb7ae659d3d314281783a0aaad562b26037
ToppCellE18.5-samps-Myeloid-Macrophage-macrophage_-_intermediate_-_unactivated|E18.5-samps / Age Group, Lineage, Cell class and subclass

CTSS CREB5

2.35e-0316220260d3fe1f5cec4285b8774ff078ebcc6bfaec26ed
ToppCellE18.5-samps-Myeloid|E18.5-samps / Age Group, Lineage, Cell class and subclass

CTSS CREB5

2.35e-0316220218e4a807e25f754a69e9eaaddfde40f8de9b8512
ToppCellE18.5-samps-Myeloid-Macrophage|E18.5-samps / Age Group, Lineage, Cell class and subclass

CTSS CREB5

2.35e-031622020970e4eda60e3f015335e2726e6d565fb2f43372
ToppCell5'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-EECs|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ABCC8 SERPINA7

2.35e-031622029f568836199a05f696294caac1ea3fa413984423
Diseaseparental longevity

SMARCA4 ABCC8 CREB5 ADGRL4

3.04e-04494204EFO_0007796
DiseasePulmonary Hypertension

SLC31A1 ATP7A

3.35e-0440202C0020542
Diseasebipolar disorder, schizophrenia

CREB5 ADGRL4

3.70e-0442202MONDO_0004985, MONDO_0005090
Diseasecoffee consumption measurement, tea consumption measurement

ZC3H4 CTSS

4.06e-0444202EFO_0006781, EFO_0010091
Diseasegeneralised epilepsy

SCN1A RYR2

5.67e-0452202EFO_0005917
Diseaseaortic measurement

NAV1 ABCC8 RYR2

6.23e-04251203EFO_0020865
Diseasealcohol dependence measurement

ARHGAP21 ABCC8

6.34e-0455202EFO_0007835
Diseasediastolic blood pressure, systolic blood pressure

NAV1 CREB5 RYR2 ADGRL4

9.55e-04670204EFO_0006335, EFO_0006336
Diseasehormone measurement

ZC3H4 RYR2

1.47e-0384202EFO_0004730
DiseaseAutism Spectrum Disorders

SCN1A RYR2

1.51e-0385202C1510586
Diseasedescending aortic diameter

NAV1 ABCC8

1.61e-0388202EFO_0021788
DiseaseNeurodevelopmental Disorders

ZC3H4 SCN1A

1.80e-0393202C1535926
Diseaseatrial fibrillation

ARHGAP21 CREB5 TLE3

1.92e-03371203EFO_0000275
Diseasealcoholic pancreatitis

TLE3 SERPINA7

2.00e-0398202EFO_1002013

Protein segments in the cluster

PeptideGeneStartEntry
DSYNMKHIHPHMNMD

ADGRL4

261

Q9HBW9
TMAHEMGHNFGMFHD

ADAM28

336

Q9UKQ2
MMVMDHHFATLHHNQ

ATP7A

671

Q04656
MMGSRQDQTPHHHMH

CREB5

261

Q02930
MEHRHNDMHYECMTP

MIPOL1

86

Q8TD10
HSMGMHSYDLGMNHL

CTSS

66

P25774
MDHSHHMGMSYMDSN

SLC31A1

1

O15431
DLHAMAEMMAENYHN

RYR2

2836

Q92736
YMHGERAHYSHTMPM

NAV1

346

Q8NEY1
QDNMHQMHKPMESMH

SMARCA4

66

P51532
DHMRAHYQTGSNHMM

SLC35B1

191

P78383
NTLFMAMEHYPMTDH

SCN1A

781

P35498
SHHLHLYMPAGMAFM

ABCC8

101

Q09428
HSRMPSMLEHVKHYM

SPART-AS1

36

P0CW21
PMMHQMEQYYHLVDM

SERPINA7

236

P05543
SYAAPFAMMSHHEMN

TLE3

366

Q04726
MHPDMHPDMHADMHA

ZC3H4

636

Q9UPT8
SKMATPYMNHYMKHQ

ZNF280C

451

Q8ND82
EDNMTHMVTHMPDQY

ARHGAP21

1311

Q5T5U3
MGMNMAAAAAHHHHH

ZIC2

221

O95409