Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionRNA-DNA hybrid ribonuclease activity

ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-11

3.10e-08111885GO:0004523
GeneOntologyMolecularFunctionRNA stem-loop binding

ERVK-6 DDX56 ERVK-7 ERVK-10 ERVK-8 ERVK-11

3.10e-08211886GO:0035613
GeneOntologyMolecularFunctionATP-dependent activity

APPBP2 SETX IPO8 ATRX MYO9A DNAH2 RNF213 DHX57 DDX56 CCT4 CHD1L IDE ATP8B2 ORC4 KIF9 DDX25 SHPRH KIF14 MYH15 KIF4B SNRNP200 SMC1B

8.39e-0861418822GO:0140657
GeneOntologyMolecularFunctionRNA-directed DNA polymerase activity

ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-11

1.31e-07141885GO:0003964
GeneOntologyMolecularFunctioninositol 1,4,5-trisphosphate-gated calcium channel activity

ITPR1 ITPR2 ITPR3

8.21e-0731883GO:0005220
GeneOntologyMolecularFunctionATP hydrolysis activity

ATRX DNAH2 RNF213 DHX57 DDX56 CCT4 CHD1L IDE ATP8B2 ORC4 KIF9 DDX25 KIF14 SNRNP200 SMC1B

1.96e-0544118815GO:0016887
GeneOntologyMolecularFunctionintracellularly gated calcium channel activity

ITPR1 ITPR2 ITPR3 MCOLN2

2.10e-05181884GO:0015278
GeneOntologyMolecularFunctionRNA endonuclease activity, producing 5'-phosphomonoesters

ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-11

2.39e-05371885GO:0016891
GeneOntologyMolecularFunctionDNA polymerase activity

ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-11

2.74e-05381885GO:0034061
GeneOntologyMolecularFunctionendonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters

ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-11

7.03e-05461885GO:0016893
GeneOntologyMolecularFunctioncytoskeletal motor activity

APPBP2 MYO9A DNAH2 KIF9 KIF14 MYH15 KIF4B

1.28e-041181887GO:0003774
GeneOntologyMolecularFunctionhelicase activity

SETX ATRX DHX57 DDX56 CHD1L DDX25 SHPRH SNRNP200

1.29e-041581888GO:0004386
GeneOntologyMolecularFunctionligand-gated calcium channel activity

ITPR1 ITPR2 ITPR3 MCOLN2

1.96e-04311884GO:0099604
GeneOntologyMolecularFunctioncatalytic activity, acting on DNA

ERVK-6 SETX ATRX ERVK-7 ISG20 CHD1L ERVK-10 ERVK-8 SHPRH ERVK-11

1.97e-0426218810GO:0140097
GeneOntologyMolecularFunctionintracellularly ligand-gated monoatomic ion channel activity

ITPR1 ITPR2 ITPR3 MCOLN2

2.52e-04331884GO:0005217
GeneOntologyMolecularFunctioninositol 1,4,5 trisphosphate binding

ITPR1 ITPR2 ITPR3

2.77e-04141883GO:0070679
GeneOntologyMolecularFunctionaspartic-type endopeptidase activity

ERVK-6 ERVK-7 ERVK-10 ERVK-8

3.94e-04371884GO:0004190
GeneOntologyMolecularFunctioncatalytic activity, acting on a nucleic acid

ERVK-6 SETX ATRX GATB DHX57 DDX56 ERVK-7 ISG20 CHD1L ERVK-10 DDX25 ERVK-8 SHPRH RARS2 ERVK-11 SNRNP200

4.13e-0464518816GO:0140640
GeneOntologyMolecularFunctionaspartic-type peptidase activity

ERVK-6 ERVK-7 ERVK-10 ERVK-8

4.37e-04381884GO:0070001
GeneOntologyMolecularFunctionmicrotubule motor activity

APPBP2 DNAH2 KIF9 KIF14 KIF4B

5.17e-04701885GO:0003777
GeneOntologyMolecularFunctioncatalytic activity, acting on RNA

ERVK-6 GATB DHX57 DDX56 ERVK-7 ISG20 ERVK-10 DDX25 ERVK-8 RARS2 ERVK-11 SNRNP200

6.15e-0441718812GO:0140098
GeneOntologyMolecularFunctioninsulin binding

IDE IGF1R

8.65e-0451882GO:0043559
GeneOntologyMolecularFunctionRNA endonuclease activity

ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-11

9.00e-04791885GO:0004521
GeneOntologyMolecularFunctionsmall GTPase binding

DOCK4 IPO8 PPP6R1 APPL2 GCC2 PRKACA DENND5A RINL TNPO3 SORL1

9.62e-0432118810GO:0031267
GeneOntologyMolecularFunctionribonucleoside triphosphate phosphatase activity

ATRX RNF112 DNAH2 RNF213 DHX57 DDX56 CCT4 CHD1L IDE ATP8B2 ORC4 KIF9 DDX25 KIF14 SNRNP200 SEPTIN12 SMC1B

1.08e-0377518817GO:0017111
GeneOntologyMolecularFunctioncAMP-dependent protein kinase activity

PRKACA PRKACB

1.79e-0371882GO:0004691
GeneOntologyMolecularFunctionK63-linked polyubiquitin modification-dependent protein binding

IKBKE OTUD7A ZRANB1

1.82e-03261883GO:0070530
GeneOntologyMolecularFunctionRNA nuclease activity

ERVK-6 ERVK-7 ISG20 ERVK-10 ERVK-8 ERVK-11

1.84e-031361886GO:0004540
GeneOntologyMolecularFunctionligand-gated monoatomic cation channel activity

KCNH7 ITPR1 ITPR2 ITPR3 KCNMB4 MCOLN2

2.13e-031401886GO:0099094
GeneOntologyMolecularFunctionGTPase binding

DOCK4 IPO8 PPP6R1 APPL2 GCC2 PRKACA DENND5A RINL TNPO3 SORL1

2.25e-0336018810GO:0051020
GeneOntologyMolecularFunctionpyrophosphatase activity

ATRX RNF112 DNAH2 RNF213 DHX57 DDX56 CCT4 CHD1L IDE ATP8B2 ORC4 KIF9 DDX25 KIF14 SNRNP200 SEPTIN12 SMC1B

2.50e-0383918817GO:0016462
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides

ATRX RNF112 DNAH2 RNF213 DHX57 DDX56 CCT4 CHD1L IDE ATP8B2 ORC4 KIF9 DDX25 KIF14 SNRNP200 SEPTIN12 SMC1B

2.53e-0384018817GO:0016817
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

ATRX RNF112 DNAH2 RNF213 DHX57 DDX56 CCT4 CHD1L IDE ATP8B2 ORC4 KIF9 DDX25 KIF14 SNRNP200 SEPTIN12 SMC1B

2.53e-0384018817GO:0016818
GeneOntologyMolecularFunctionmicrotubule binding

APPBP2 DYSF CEP350 KIF9 MACO1 CEP135 KIF14 KIF4B CEP295

2.64e-033081889GO:0008017
GeneOntologyMolecularFunctionalcohol binding

ITPR1 ITPR2 ITPR3 OSBPL7 OSBP2

2.80e-031021885GO:0043178
GeneOntologyMolecularFunctioncyclic nucleotide-dependent protein kinase activity

PRKACA PRKACB

3.04e-0391882GO:0004690
GeneOntologyMolecularFunctionmodification-dependent protein binding

ATRX CHD1L IDE IKBKE BRD9 OTUD7A ZRANB1

3.44e-032061887GO:0140030
GeneOntologyBiologicalProcessDNA integration

ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-11

7.43e-08131895GO:0015074
GeneOntologyBiologicalProcessmicrotubule cytoskeleton organization

CFAP47 ATRX DNAH2 CDK11A DYSF CCDC39 CEP350 FSIP2 CCDC13 ARHGEF10 GCC2 SYNE2 PDE4DIP CEP135 NINL KIF14 KIF4B CEP295 CTNNB1 PCM1 BBOF1

3.02e-0672018921GO:0000226
GeneOntologyBiologicalProcessRNA-templated DNA biosynthetic process

ERVK-6 CCT4 ERVK-7 ERVK-10 ERVK-8 CTNNB1 ERVK-11

1.12e-05831897GO:0006278
GeneOntologyBiologicalProcessmicrotubule-based process

CFAP47 SEMG1 ATRX DNAH2 CDK11A DYSF CCDC39 CEP350 FSIP2 CCDC13 KIF9 CFAP54 ARHGEF10 GCC2 SYNE2 PDE4DIP CEP135 NINL KIF14 KIF4B CEP295 CTNNB1 PCM1 SEPTIN12 BBOF1

1.34e-05105818925GO:0007017
GeneOntologyBiologicalProcesssexual reproduction

CFAP47 SEMG1 SETX ANGPT2 DPY19L2 ATRX PAQR8 RAD21L1 CCT4 TRIM27 TDRD1 ITPR1 FSIP2 ORC4 LIF CFAP54 IGF1R ANAPC1 AGT PRKACA DDX25 PRKACB OSBP2 CTNNB1 VPS13B SEPTIN12 SMC1B BBOF1

2.52e-05131218928GO:0019953
GeneOntologyBiologicalProcesscilium assembly

CFAP47 ZNF423 TBC1D2 DNAH2 CCDC39 CEP350 FSIP2 CCDC13 CFAP54 SYNE2 CEP135 SNX10 PCM1 BBOF1

6.34e-0544418914GO:0060271
GeneOntologyBiologicalProcessmicrotubule anchoring

CEP350 GCC2 NINL PCM1

7.43e-05251894GO:0034453
GeneOntologyBiologicalProcessDNA synthesis involved in DNA repair

ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-11

7.62e-05481895GO:0000731
GeneOntologyBiologicalProcesscellular process involved in reproduction in multicellular organism

CFAP47 SEMG1 ANGPT2 DPY19L2 PAQR8 TDRD1 FSIP2 ORC4 CFAP54 PRKACA DDX25 OSBP2 CTNNB1 VPS13B BBOF1

1.09e-0452718915GO:0022412
GeneOntologyBiologicalProcesscilium organization

CFAP47 ZNF423 TBC1D2 DNAH2 CCDC39 CEP350 FSIP2 CCDC13 CFAP54 SYNE2 CEP135 SNX10 PCM1 BBOF1

1.32e-0447618914GO:0044782
GeneOntologyBiologicalProcesscilium movement involved in cell motility

CFAP47 SEMG1 DNAH2 CCDC39 FSIP2 KIF9 CFAP54 SEPTIN12 BBOF1

1.43e-042101899GO:0060294
GeneOntologyBiologicalProcessgerm cell development

CFAP47 SEMG1 ANGPT2 DPY19L2 PAQR8 TDRD1 FSIP2 CFAP54 PRKACA DDX25 OSBP2 CTNNB1 VPS13B BBOF1

1.51e-0448218914GO:0007281
GeneOntologyBiologicalProcessspermatid development

CFAP47 SEMG1 DPY19L2 FSIP2 CFAP54 PRKACA DDX25 OSBP2 VPS13B BBOF1

1.58e-0426218910GO:0007286
GeneOntologyBiologicalProcesscilium-dependent cell motility

CFAP47 SEMG1 DNAH2 CCDC39 FSIP2 KIF9 CFAP54 SEPTIN12 BBOF1

1.70e-042151899GO:0060285
GeneOntologyBiologicalProcesscilium or flagellum-dependent cell motility

CFAP47 SEMG1 DNAH2 CCDC39 FSIP2 KIF9 CFAP54 SEPTIN12 BBOF1

1.70e-042151899GO:0001539
GeneOntologyBiologicalProcessspermatid differentiation

CFAP47 SEMG1 DPY19L2 FSIP2 CFAP54 PRKACA DDX25 OSBP2 VPS13B BBOF1

2.14e-0427218910GO:0048515
GeneOntologyBiologicalProcessmulticellular organismal reproductive process

CFAP47 SEMG1 SETX ANGPT2 DPY19L2 ATRX KALRN PAQR8 RAD21L1 TRIM27 TDRD1 FSIP2 ORC4 LIF CFAP54 IGF1R AGT PRKACA DDX25 OSBP2 CTNNB1 VPS13B SEPTIN12 BBOF1

2.48e-04119418924GO:0048609
GeneOntologyBiologicalProcessmicrotubule organizing center organization

CDK11A ARHGEF10 GCC2 PDE4DIP CEP135 CEP295 CTNNB1 PCM1

2.52e-041791898GO:0031023
GeneOntologyCellularComponentplatelet dense tubular network membrane

ITPR1 ITPR2 ITPR3

5.87e-0591893GO:0031095
GeneOntologyCellularComponentplatelet dense tubular network

ITPR1 ITPR2 ITPR3

1.14e-04111893GO:0031094
GeneOntologyCellularComponentt-UTP complex

HEATR1 UTP4

2.42e-0431892GO:0034455
GeneOntologyCellularComponentnuclear envelope

DPY19L2 IPO8 TRIM27 ITPR1 ITPR3 ADRA1B MACO1 SYNE2 OSBPL7 CTNNB1 TNPO3 PCID2 PCM1 SORL1

5.97e-0456018914GO:0005635
GeneOntologyCellularComponentsarcoplasm

HK2 ITPR1 ITPR2 ITPR3 SYNE2 SERTAD1

6.00e-041141896GO:0016528
GeneOntologyCellularComponentcentrosome

HK2 CCT4 DYSF CEP350 CCDC13 ARHGEF10 ZBED6 NEK8 PDE4DIP PRKACA CEP135 SNX10 PRKACB NINL CEP295 CTNNB1 PCM1

6.48e-0477018917GO:0005813
GeneOntologyCellularComponentmicrotubule organizing center

HK2 EVC CCT4 DYSF CEP350 CCDC13 ARHGEF10 ZBED6 NEK8 PDE4DIP PRKACA CEP135 SNX10 PRKACB NINL CEP295 CTNNB1 PCM1 BBOF1

6.92e-0491918919GO:0005815
HumanPhenoAbnormality of the capitate bone

EVC2 EVC PRKACA PRKACB

1.11e-0512654HP:0004262
HumanPhenoAbnormality of the hamate bone

EVC2 EVC PRKACA PRKACB

1.11e-0512654HP:0004259
HumanPhenoCapitate-hamate fusion

EVC2 EVC PRKACA PRKACB

1.11e-0512654HP:0001241
HumanPhenoNeonatal short-limb short stature

EVC2 EVC PRKACA PRKACB

2.20e-0514654HP:0008921
HumanPhenoEpispadias

EVC2 EVC ORC4 PRKACA PRKACB

2.71e-0529655HP:0000039
HumanPhenoShort limb dwarfism

EVC2 EVC PRKACA PRKACB

8.11e-0519654HP:0003505
HumanPhenoAbnormal incisor morphology

EVC2 EVC PRKACA PRKACB NHS VPS13B

1.20e-0462656HP:0011063
HumanPhenoDwarfism

EVC2 EVC PRKACA PRKACB

1.23e-0421654HP:0001516
DomainInsP3_rcpt-bd

ITPR1 ITPR2 ITPR3

8.95e-0731813IPR000493
DomainLRRCT

TLR7 LRIG3 TLR2 CD180 TPBG

1.32e-05321815PF01463
DomainRIH_assoc-dom

ITPR1 ITPR2 ITPR3

1.75e-0561813IPR013662
DomainIns145_P3_rec

ITPR1 ITPR2 ITPR3

1.75e-0561813PF08709
DomainRIH_assoc

ITPR1 ITPR2 ITPR3

1.75e-0561813PF08454
DomainRIH_dom

ITPR1 ITPR2 ITPR3

1.75e-0561813IPR000699
DomainIns145_P3_rcpt

ITPR1 ITPR2 ITPR3

1.75e-0561813IPR014821
DomainRyanodine_recept-rel

ITPR1 ITPR2 ITPR3

1.75e-0561813IPR015925
Domain-

ITPR1 ITPR2 ITPR3

1.75e-05618131.25.10.30
DomainRYDR_ITPR

ITPR1 ITPR2 ITPR3

1.75e-0561813PF01365
DomainLRR_8

LRRC8C LRRC57 TLR7 ISLR LRIG3 TLR2 LGR6 CD180 TPBG

4.48e-051711819PF13855
DomainLRR_TYP

LRRC8C LRRC57 TLR7 ISLR LRIG3 TLR2 LGR6 CD180 TPBG

5.85e-051771819SM00369
DomainLeu-rich_rpt_typical-subtyp

LRRC8C LRRC57 TLR7 ISLR LRIG3 TLR2 LGR6 CD180 TPBG

5.85e-051771819IPR003591
DomainLeu-rich_rpt

LRRC8C LRRC57 TLR7 ISLR LRIG3 TLR2 LGR6 CD180 TPBG NLRP13 LRRC74B

6.99e-0527118111IPR001611
DomainHelicase_C

ATRX DHX57 DDX56 CHD1L DDX25 SHPRH SNRNP200

8.25e-051071817PF00271
DomainHELICc

ATRX DHX57 DDX56 CHD1L DDX25 SHPRH SNRNP200

8.25e-051071817SM00490
DomainHelicase_C

ATRX DHX57 DDX56 CHD1L DDX25 SHPRH SNRNP200

8.75e-051081817IPR001650
DomainL_dom-like

LRRC8C LRRC57 TLR7 ISLR LRIG3 IGF1R TLR2 LGR6 CD180 TPBG NLRP13 LRRC74B

8.86e-0532818112IPR032675
DomainHELICASE_CTER

ATRX DHX57 DDX56 CHD1L DDX25 SHPRH SNRNP200

9.27e-051091817PS51194
DomainHELICASE_ATP_BIND_1

ATRX DHX57 DDX56 CHD1L DDX25 SHPRH SNRNP200

9.27e-051091817PS51192
DomainDEXDc

ATRX DHX57 DDX56 CHD1L DDX25 SHPRH SNRNP200

9.27e-051091817SM00487
DomainLimbin/Ellis-van_Creveld

EVC2 EVC

9.34e-0521812IPR026501
DomainHelicase_ATP-bd

ATRX DHX57 DDX56 CHD1L DDX25 SHPRH SNRNP200

9.82e-051101817IPR014001
DomainMIR

ITPR1 ITPR2 ITPR3

1.02e-04101813PF02815
DomainMIR_motif

ITPR1 ITPR2 ITPR3

1.02e-04101813IPR016093
DomainMIR

ITPR1 ITPR2 ITPR3

1.02e-04101813PS50919
DomainMIR

ITPR1 ITPR2 ITPR3

1.02e-04101813SM00472
DomainARM-type_fold

DCAF1 CAB39 IPO8 PPP6R1 HEATR1 ITPR1 ITPR2 PELP1 CEBPZ INTS4 CTNNB1 TNPO3

1.21e-0433918112IPR016024
DomainIon_trans_dom

KCNH7 TRPM7 ITPR1 ITPR2 ITPR3 MCOLN2 KCNH5

1.23e-041141817IPR005821
DomainIon_trans

KCNH7 TRPM7 ITPR1 ITPR2 ITPR3 MCOLN2 KCNH5

1.23e-041141817PF00520
DomainLRR

LRRC8C LRRC57 TLR7 ISLR LRIG3 TLR2 LGR6 CD180 TPBG

1.55e-042011819PS51450
DomainP-loop_NTPase

SETX ATRX MYO9A RNF112 DNAH2 RNF213 DHX57 DDX56 CHD1L ORC4 KIF9 DDX25 SHPRH KIF14 MYH15 KIF4B SNRNP200 SEPTIN12 SMC1B NLRP13

2.19e-0484818120IPR027417
DomainCys-rich_flank_reg_C

TLR7 ISLR LRIG3 TLR2 CD180 TPBG

2.42e-04901816IPR000483
DomainLRRCT

TLR7 ISLR LRIG3 TLR2 CD180 TPBG

2.42e-04901816SM00082
DomainLRR_1

LRRC8C LRRC57 TLR7 ISLR LRIG3 TLR2 LGR6 CD180 TPBG

2.93e-042191819PF00560
Domain-

LRRC8C LRRC57 TLR7 ISLR LRIG3 TLR2 LGR6 CD180 TPBG NLRP13 LRRC74B

3.07e-04321181113.80.10.10
DomainARM-like

DCAF1 CAB39 SETX IPO8 HEATR1 PELP1 INTS4 CTNNB1 TNPO3

1.31e-032701819IPR011989
PathwayKEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PRKN_TO_MGLUR1_SIGNALING_PATHWAY

ITPR1 ITPR2 ITPR3

9.45e-0651403M49000
PathwayREACTOME_GLUCAGON_LIKE_PEPTIDE_1_GLP1_REGULATES_INSULIN_SECRETION

ITPR1 ITPR2 ITPR3 PRKACA PRKACB

1.46e-05321405MM14983
PathwayKEGG_OOCYTE_MEIOSIS

ITPR1 ITPR2 ITPR3 IGF1R ANAPC1 PRKACA PRKACB SMC1B

1.65e-051131408M16817
PathwayKEGG_MEDICUS_REFERENCE_CA2_PLCD_ITPR_SIGNALING_PATHWAY

ITPR1 ITPR2 ITPR3

1.88e-0561403M47960
PathwayREACTOME_DAG_AND_IP3_SIGNALING

ITPR1 ITPR2 ITPR3 PRKACA PRKACB

5.06e-05411405M512
PathwayREACTOME_GLUCAGON_LIKE_PEPTIDE_1_GLP1_REGULATES_INSULIN_SECRETION

ITPR1 ITPR2 ITPR3 PRKACA PRKACB

5.69e-05421405M791
PathwayWP_HEDGEHOG_SIGNALING_WP4249

EVC2 EVC PRKACA PRKACB SPOP

6.39e-05431405M39706
PathwayKEGG_MEDICUS_REFERENCE_BCR_PLCG_ITPR_SIGNALING_PATHWAY

ITPR1 ITPR2 ITPR3

7.71e-0591403M47852
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SPTBN2_TO_MGLUR1_TRPC3_SIGNALING_PATHWAY

ITPR1 ITPR2 ITPR3

1.09e-04101403M47661
PathwayKEGG_VASCULAR_SMOOTH_MUSCLE_CONTRACTION

ITPR1 ITPR2 ITPR3 ADRA1B PRKACA PRKACB KCNMB4

1.47e-041151407M9387
PathwayKEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_PRKCG_TO_MGLUR1_TRPC3_SIGNALING_PATHWAY

ITPR1 ITPR2 ITPR3

1.49e-04111403M49033
PathwayREACTOME_CLEC7A_DECTIN_1_INDUCES_NFAT_ACTIVATION

ITPR1 ITPR2 ITPR3

1.49e-04111403M27466
PathwayREACTOME_G_PROTEIN_MEDIATED_EVENTS

ITPR1 ITPR2 ITPR3 PRKACA PRKACB

1.92e-04541405M26911
PathwayKEGG_MEDICUS_REFERENCE_MGLUR1_TRPC3_SIGNALING_PATHWAY

ITPR1 ITPR2 ITPR3

2.55e-04131403M47656
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_PSEN1_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY

ITPR1 ITPR2 ITPR3

2.55e-04131403M47696
PathwayKEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_SIGMAR1_TO_CA2_APOPTOTIC_PATHWAY

ITPR1 ITPR2 ITPR3

2.55e-04131403M47751
PathwayREACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS

ITPR1 ITPR2 ITPR3

2.55e-04131403MM14553
PathwayREACTOME_REGULATION_OF_INSULIN_SECRETION

ITPR1 ITPR2 ITPR3 PRKACA PRKACB

3.42e-04611405MM15071
PathwayREACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS

ITPR1 ITPR2 ITPR3

4.88e-04161403M26945
PathwayKEGG_LONG_TERM_POTENTIATION

ITPR1 ITPR2 ITPR3 PRKACA PRKACB

6.48e-04701405M3115
PathwayREACTOME_SIGNALING_BY_VEGF

ITPR1 ITPR2 ITPR3 PRKACA PRKACB CTNNB1

6.52e-041061406M27077
PathwayREACTOME_INTEGRATION_OF_ENERGY_METABOLISM

ITPR1 ITPR2 ITPR3 PRKACA PRKACB

7.38e-04721405MM14631
PathwayREACTOME_VEGFR2_MEDIATED_CELL_PROLIFERATION

ITPR1 ITPR2 ITPR3

8.27e-04191403M27423
PathwayKEGG_MEDICUS_VARIANT_SCRAPIE_CONFORMATION_PRPSC_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY

ITPR1 ITPR2 ITPR3

8.27e-04191403M47760
PathwayKEGG_MEDICUS_REFERENCE_TCR_PLCG_ITPR_SIGNALING_PATHWAY

ITPR1 ITPR2 ITPR3

8.27e-04191403M47733
PathwayWP_RENINANGIOTENSINALDOSTERONE_SYSTEM_RAAS

ITPR1 ITPR2 ITPR3 AGT

9.30e-04441404M39845
PathwayREACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_KEY_METABOLIC_FACTORS

PRKACA PRKACB

9.60e-0451402M26988
PathwayKEGG_MEDICUS_REFERENCE_RORA_MEDIATED_TRANSCRIPTION

ITPR1 RORA

9.60e-0451402M49011
PathwayKEGG_MEDICUS_REFERENCE_MACHR_CA2_APOPTOTIC_PATHWAY

ITPR1 ITPR2 ITPR3

9.66e-04201403M47688
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

DCAF1 IPO8 NOP56 ATRX MBOAT7 TRPM7 GATB PPP6R1 HEATR1 TRIM27 ITPR1 ITPR2 ITPR3 SLC12A2 SACS ARHGEF10 CEBPZ MACO1 UTP4 SYNE2 PRKACA PRKACB MRPS9 CTNNB1 RPP25L SNRNP200 IMMT RPL7A VPS13B PCM1 GOLGB1

1.71e-1014871913133957083
Pubmed

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

HK2 IPO8 NOP56 RBBP7 PACSIN3 RNF213 DHX57 DDX56 CCT4 PPP6R1 HEATR1 TRIM27 ITPR1 ITPR2 ITPR3 PELP1 CEBPZ MACO1 SYNE2 MRPS9 KIF14 RARS2 CTNNB1 SLC39A14 SNRNP200 TNPO3 PCM1 CCDC93

6.63e-0914401912830833792
Pubmed

Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.

APPBP2 IPO8 HEATR1 IDE CEP350 CEBPZ GCC2 MACO1 PDE4DIP PRKACA CEP135 MRPS9 NINL INTS4 SLC39A14 TNPO3 PCM1 GOLGB1 CCDC93

4.25e-087541911933060197
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

SETX MAN2A1 ATRX MBOAT7 RBBP7 PACSIN3 CDK11A DHX57 DDX56 CCT4 ICE1 HEATR1 TRIM27 ORC4 APPL2 SLC12A2 CEBPZ ANAPC1 ZBED6 MACO1 UTP4 BRD9 PRKACA KIF14 IMMT PCID2 GOLGB1

5.94e-0814971912731527615
Pubmed

Ellis-van Creveld Syndrome

EVC2 EVC PRKACA PRKACB

1.09e-079191437903214
Pubmed

C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.

MBOAT7 TRPM7 APBB2 DHX57 ITPR1 ITPR2 ITPR3 LRIG3 APPL2 SLC12A2 MACO1 SYNE2 IMMT VPS13B GOLGB1

1.47e-075041911534432599
Pubmed

Inositol 1,4,5-trisphosphate receptors are autoantibody target antigens in patients with Sjögren's syndrome and other systemic rheumatic diseases.

ITPR1 ITPR2 ITPR3

1.63e-073191317437169
Pubmed

Decreased olfactory mucus secretion and nasal abnormality in mice lacking type 2 and type 3 IP3 receptors.

ITPR1 ITPR2 ITPR3

1.63e-073191318547250
Pubmed

Inositol 1,4,5-trisphosphate receptor gene variants are related to the risk of breast cancer in a Chinese population.

ITPR1 ITPR2 ITPR3

1.63e-073191336350267
Pubmed

The versatility and universality of calcium signalling.

ITPR1 ITPR2 ITPR3

1.63e-073191311413485
Pubmed

Using concatenated subunits to investigate the functional consequences of heterotetrameric inositol 1,4,5-trisphosphate receptors.

ITPR1 ITPR2 ITPR3

1.63e-073191326009177
Pubmed

Receptor-activated single channels in intact human platelets.

ITPR1 ITPR2 ITPR3

1.63e-07319131693919
Pubmed

Type 3 Inositol 1,4,5-Trisphosphate Receptor is a Crucial Regulator of Calcium Dynamics Mediated by Endoplasmic Reticulum in HEK Cells.

ITPR1 ITPR2 ITPR3

1.63e-073191331979185
Pubmed

Expression of inositol 1,4,5-trisphosphate receptors in mouse oocytes and early embryos: the type I isoform is upregulated in oocytes and downregulated after fertilization.

ITPR1 ITPR2 ITPR3

1.63e-07319139808793
Pubmed

Type 2 and type 3 inositol 1,4,5-trisphosphate (IP3) receptors promote the differentiation of granule cell precursors in the postnatal cerebellum.

ITPR1 ITPR2 ITPR3

1.63e-073191318194433
Pubmed

Predominant role of type 1 IP3 receptor in aortic vascular muscle contraction.

ITPR1 ITPR2 ITPR3

1.63e-073191318241669
Pubmed

Granulosa cells express three inositol 1,4,5-trisphosphate receptor isoforms: cytoplasmic and nuclear Ca2+ mobilization.

ITPR1 ITPR2 ITPR3

1.63e-073191319068129
Pubmed

Molecular basis of the isoform-specific ligand-binding affinity of inositol 1,4,5-trisphosphate receptors.

ITPR1 ITPR2 ITPR3

1.63e-073191317327232
Pubmed

Evidence that type I, II, and III inositol 1,4,5-trisphosphate receptors can occur as integral plasma membrane proteins.

ITPR1 ITPR2 ITPR3

1.63e-073191310874040
Pubmed

Abnormal distribution of inositol 1,4,5-trisphosphate receptors in human muscle can be related to altered calcium signals and gene expression in Duchenne dystrophy-derived cells.

ITPR1 ITPR2 ITPR3

1.63e-073191320395455
Pubmed

Functional inositol 1,4,5-trisphosphate receptors assembled from concatenated homo- and heteromeric subunits.

ITPR1 ITPR2 ITPR3

1.63e-073191323955339
Pubmed

Tsg101 regulates PI(4,5)P2/Ca(2+) signaling for HIV-1 Gag assembly.

ITPR1 ITPR2 ITPR3

1.63e-073191324904548
Pubmed

Differential distribution of inositol trisphosphate receptor isoforms in mouse oocytes.

ITPR1 ITPR2 ITPR3

1.63e-07319139858485
Pubmed

IP3 receptors regulate vascular smooth muscle contractility and hypertension.

ITPR1 ITPR2 ITPR3

1.63e-073191327777977
Pubmed

Differential inositol 1,4,5-trisphosphate receptor signaling in a neuronal cell line.

ITPR1 ITPR2 ITPR3

1.63e-073191317581770
Pubmed

Nuclear inositol 1,4,5-trisphosphate receptors regulate local Ca2+ transients and modulate cAMP response element binding protein phosphorylation.

ITPR1 ITPR2 ITPR3

1.63e-073191316014380
Pubmed

Knockdown of the type 2 and 3 inositol 1,4,5-trisphosphate receptors suppresses muscarinic antinociception in mice.

ITPR1 ITPR2 ITPR3

1.63e-073191317890015
Pubmed

Inositol 1, 4, 5-trisphosphate receptors and human left ventricular myocytes.

ITPR1 ITPR2 ITPR3

1.63e-073191323983250
Pubmed

Activation of the inositol (1,4,5)-triphosphate calcium gate receptor is required for HIV-1 Gag release.

ITPR1 ITPR2 ITPR3

1.63e-073191320427533
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

DOCK4 SETX ATRX MYO9A RBBP7 CDK11A PPP6R1 RUFY1 ANAPC1 MACO1 UTP4 KIF14 CTNNB1 PCM1 GOLGB1 SORL1

1.88e-075881911638580884
Pubmed

A High-Density Human Mitochondrial Proximity Interaction Network.

HK2 IPO8 NOP56 TRPM7 GATB RNF213 DHX57 DDX56 CCT4 HEATR1 IDE ITPR1 ITPR2 ITPR3 SLC12A2 MACO1 UTP4 SYNE2 PRKACA MRPS9 RARS2 SLC39A14 MTO1 IMMT VPS13B GOLGB1

2.19e-0714961912632877691
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

NOP56 PACSIN3 DDX56 CCT4 HEATR1 ITPR2 ITPR3 CEP350 SLC12A2 PELP1 SACS CEBPZ UTP4 SYNE2 KIF14 CTNNB1 SNRNP200 IMMT RPL7A PCM1 GOLGB1

2.54e-0710241912124711643
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

DOCK4 JCAD SETX TRPM7 MYO9A RBBP7 CEP350 FSIP2 IGF1R SLC12A2 ARHGEF10 IKBKE SYNE2 OTUD7A KIF14 NHS TNPO3 PCM1 GOLGB1

3.27e-078611911936931259
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

JCAD CTNNAL1 RNF213 CCT4 PPP6R1 IDE PPEF1 ITPR1 ITPR2 ITPR3 CEP350 SLC12A2 CEBPZ MACO1 SYNE2 PRKACA CEP135 INTS4 KIF14 NHS EIF2AK4

3.76e-0710491912127880917
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

NOP56 ATRX PCDHGB7 DNAH2 GATB DHX57 CCT4 ZBTB41 HEATR1 PHEX SACS CEBPZ SYNE2 PRKACA PRKACB MRPS9 MYH15 CEP295 EIF2AK4 ITIH6 IMMT RPL7A PCID2 GOLGB1 BBOF1

4.01e-0714421912535575683
Pubmed

Virus-Host Interactome and Proteomic Survey Reveal Potential Virulence Factors Influencing SARS-CoV-2 Pathogenesis.

DCAF1 DPY19L2 RUFY1 ITPR2 ITPR3 RNF20 CEP135 RARS2 IMMT PCM1 GOLGB1

5.78e-072851911132838362
Pubmed

Loss of IP3R-dependent Ca2+ signalling in thymocytes leads to aberrant development and acute lymphoblastic leukemia.

ITPR1 ITPR2 ITPR3

6.50e-074191325215520
Pubmed

Alternative splice variants of hTrp4 differentially interact with the C-terminal portion of the inositol 1,4,5-trisphosphate receptors.

ITPR1 ITPR2 ITPR3

6.50e-074191311163362
Pubmed

Many human endogenous retrovirus K (HERV-K) proviruses are unique to humans.

ERVK-6 ERVK-7 ERVK-10

6.50e-074191310469592
Pubmed

Inositol 1, 4, 5-trisphosphate receptor interacts with the SNARE domain of syntaxin 1B.

ITPR1 ITPR2 ITPR3

6.50e-074191321424589
Pubmed

Loss of IP3 Receptor-Mediated Ca2+ Release in Mouse B Cells Results in Abnormal B Cell Development and Function.

ITPR1 ITPR2 ITPR3

6.50e-074191328615414
Pubmed

Distinct localization and function of (1,4,5)IP(3) receptor subtypes and the (1,3,4,5)IP(4) receptor GAP1(IP4BP) in highly purified human platelet membranes.

ITPR1 ITPR2 ITPR3

6.50e-074191310828023
Pubmed

IP3R-mediated Ca2+ signals govern hematopoietic and cardiac divergence of Flk1+ cells via the calcineurin-NFATc3-Etv2 pathway.

ITPR1 ITPR2 ITPR3

6.50e-074191328419336
Pubmed

IP3R-mediated Ca2+ signaling controls B cell proliferation through metabolic reprogramming.

ITPR1 ITPR2 ITPR3

6.50e-074191335494252
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

CFAP47 LRRC8C APPBP2 SETX RNF112 TBC1D2 DNAH2 RNF213 ZBTB41 ICE1 PPP6R1 PARVG CCDC39 ITPR2 CEP295 C6 SNRNP200

7.55e-077361911729676528
Pubmed

HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.

PPP1R21 JCAD IPO8 NOP56 DNAH2 HEATR1 TRIM27 CCDC39 ITPR1 SYNE2 SHPRH KIF14 ZRANB1 SNRNP200 IMMT PCID2 GOLGB1

1.05e-067541911735906200
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

SETX TRPM7 APBB2 RNF213 CCT4 RUFY1 CEP350 LRIG3 SLC12A2 ZBED6 GCC2 MRPS9 SLC39A14 SNRNP200 RPL7A PCM1 GOLGB1

1.58e-067771911735844135
Pubmed

InsP₃receptors and Orai channels in pancreatic acinar cells: co-localization and its consequences.

ITPR1 ITPR2 ITPR3

1.62e-065191321568942
Pubmed

A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.

DCAF1 SEMG1 CTNNAL1 IPO8 RBBP7 CCT4 PPP6R1 HEATR1 IDE PPEF1 ITPR3 MACO1 CORO7 SNRNP200 IMMT TNPO3 RPL7A PCM1 SORL1

2.04e-069741911928675297
Pubmed

Defining the membrane proteome of NK cells.

PPP1R21 LRRC8C ACAP1 HK2 MAN2A1 NOP56 MBOAT7 RNF213 DDX56 HEATR1 ITPR1 ITPR2 ITPR3 CEP350 PELP1 GCC2 KIF14 CORO7 IMMT PCM1 GOLGB1

2.08e-0611681912119946888
Pubmed

Essential Roles of Intracellular Calcium Release Channels in Muscle, Brain, Metabolism, and Aging.

ITPR1 ITPR2 ITPR3

3.22e-066191325966694
Pubmed

A calcium-induced calcium release mechanism supports luteinizing hormone-induced testosterone secretion in mouse Leydig cells.

ITPR1 ITPR2 ITPR3

3.22e-066191320519450
Pubmed

Roles of I(f) and intracellular Ca2+ release in spontaneous activity of ventricular cardiomyocytes during murine embryonic development.

ITPR1 ITPR2 ITPR3

3.22e-066191323463619
Pubmed

Sprouty2 regulates PI(4,5)P2/Ca2+ signaling and HIV-1 Gag release.

ITPR1 ITPR2 ITPR3

3.22e-066191321762810
Pubmed

IP3Rs are sufficient for dendritic cell Ca2+ signaling in the absence of RyR1.

ITPR1 ITPR2 ITPR3

3.22e-066191316844763
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

RBBP7 DHX57 DDX56 HEATR1 ITPR3 PELP1 CEBPZ ANAPC1 UTP4 SYNE2 KIF14 SNRNP200 IMMT RPL7A PCM1

3.70e-066531911522586326
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

DCAF1 SEMG1 RBBP7 RNF213 DDX56 PPP6R1 TRIM27 LRIG3 MCTP1 ZFHX4 ANAPC1 BRD9 RARS2 CEP295 SPOP TRAF3IP3 MTO1 PCID2 PCM1 SORL1

3.88e-0611161912031753913
Pubmed

The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells.

DCAF1 RMND5B CDK11A PPP6R1 ZFHX4 PELP1 ANAPC1 MRPS9 CTNNB1 TNPO3

4.05e-062821911023667531
Pubmed

The human cytoplasmic dynein interactome reveals novel activators of motility.

DOCK4 JCAD IPO8 CCT4 RUFY1 MSTO1 CEP350 MACO1 CEP135 PRKACB NINL KIF14 CEP295 RPP25L RINL PCID2 PCM1

5.45e-068531911728718761
Pubmed

Developmental expression of the calcium release channels during early neurogenesis of the mouse cerebral cortex.

ITPR1 ITPR2 ITPR3

5.61e-067191311860456
Pubmed

Inositol-1,4,5-trisphosphate receptor regulates hepatic gluconeogenesis in fasting and diabetes.

ITPR1 ITPR2 ITPR3

5.61e-067191322495310
Pubmed

Trabid, a new positive regulator of Wnt-induced transcription with preference for binding and cleaving K63-linked ubiquitin chains.

OTUD7A CTNNB1 ZRANB1

5.61e-067191318281465
Pubmed

The bHLH transcription factor Mist1 is required to maintain exocrine pancreas cell organization and acinar cell identity.

ITPR1 ITPR2 ITPR3 CTNNB1

5.97e-0622191411696558
Pubmed

FAM105A/OTULINL Is a Pseudodeubiquitinase of the OTU-Class that Localizes to the ER Membrane.

CAB39 LRRC8C MBOAT7 TRPM7 APBB2 ITPR1 ITPR2 ITPR3 SLC12A2 MACO1 SYNE2 GOLGB1

1.21e-054681911231056421
Pubmed

Tonic B cell activation by Radioprotective105/MD-1 promotes disease progression in MRL/lpr mice.

TLR7 TLR2 CD180

1.34e-059191318492657
Pubmed

Ca2+ signals regulate mitochondrial metabolism by stimulating CREB-mediated expression of the mitochondrial Ca2+ uniporter gene MCU.

ITPR1 ITPR2 ITPR3

1.34e-059191325737585
Pubmed

Arf GTPase-activating protein ASAP1 interacts with Rab11 effector FIP3 and regulates pericentrosomal localization of transferrin receptor-positive recycling endosome.

ACAP1 PDE4DIP RNF20 GOLGB1

1.40e-0527191418685082
Pubmed

Competitive binding of E3 ligases TRIM26 and WWP2 controls SOX2 in glioblastoma.

SEMG1 NOP56 MYO9A PPFIBP2 DHX57 DDX56 CCT4 HEATR1 IDE ITPR2 MACO1 AGT MRPS9 KIF14 CTNNB1

1.43e-057321911534732716
Pubmed

Gene expression in the developing mouse retina by EST sequencing and microarray analysis.

CCT4 CCDC13 ZFHX4 ZNF780A RNF20 NHS CEP295

1.44e-05142191711812828
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

RNF213 ICE1 ITPR2 CEP350 SLC12A2 ARHGEF10 CEBPZ ANAPC1 MACO1 CEP135 KIF14 CEP295 CTNNB1 CORO7 PCM1

1.46e-057331911534672954
Pubmed

The PITSLRE/CDK11p58 protein kinase promotes centrosome maturation and bipolar spindle formation.

CDK11A PRKACA CEP135 NINL PCM1

1.57e-0557191516462731
Pubmed

Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods.

CEP350 PDE4DIP PRKACA CEP135 PRKACB CEP295 PCM1

1.72e-05146191721399614
Pubmed

LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.

DCAF1 RNF112 DHX57 ICE1 ITPR3 ANAPC1 EIF2AK4 SNRNP200

1.72e-05202191833005030
Pubmed

Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis.

MBOAT7 TRPM7 RUFY1 ITPR1 ITPR3 SLC12A2 GCC2 MACO1 SYNE2 SLC39A14 VPS13B PCID2 PCM1

1.74e-055681911337774976
Pubmed

Exploring an Alternative Cysteine-Reactive Chemistry to Enable Proteome-Wide PPI Analysis by Cross-Linking Mass Spectrometry.

RBBP7 CCT4 DSN1 ORC4 PELP1 CEBPZ MRPS9 INTS4 OSBP2 CTNNB1 RPL7A

1.90e-054111911136652389
Pubmed

SHLD2/FAM35A co-operates with REV7 to coordinate DNA double-strand break repair pathway choice.

IPO8 NOP56 RBBP7 DDX56 CHD1L ITPR2 IMMT

2.05e-05150191730154076
Pubmed

Phosphoproteome analysis of the human mitotic spindle.

NOP56 DSN1 CEP350 PELP1 CEBPZ ANAPC1 SNRNP200 PCM1

2.28e-05210191816565220
Pubmed

Type 1 and 3 inositol trisphosphate receptors are required for extra-embryonic vascular development.

ITPR1 ITPR2 ITPR3

2.60e-0511191327514653
Pubmed

Human gingiva transcriptome during wound healing.

DYSF AGT MYH15 LGR6 CD180 NNMT

2.89e-05107191628005267
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

JCAD ATRX KALRN TRPM7 ZNF423 APBB2 ZNF214 MSTO1 CEP350 CCDC13 KANSL2 APPL2 SACS ARHGEF10 PDE4DIP MRPS9 MGAT5B SNRNP200 IMMT PCM1

2.97e-0512851912035914814
Pubmed

DOCK4 promotes loss of proliferation in glioblastoma progenitor cells through nuclear beta-catenin accumulation and subsequent miR-302-367 cluster expression.

DOCK4 CTNNB1

3.00e-052191228925399
Pubmed

Phosphorylation of inositol 1,4,5-trisphosphate receptors in parotid acinar cells. A mechanism for the synergistic effects of cAMP on Ca2+ signaling.

ITPR2 PRKACA

3.00e-052191211694504
Pubmed

Evidence for a second isoform of the catalytic subunit of cAMP-dependent protein kinase.

PRKACA PRKACB

3.00e-05219123023318
Pubmed

The Pro335 --> Leu polymorphism of type 3 inositol 1,4,5-trisphosphate receptor found in mouse inbred lines results in functional change.

ITPR1 ITPR3

3.00e-052191215890645
Pubmed

Cloning and characterization of human type 2 and type 3 inositol 1,4,5-trisphosphate receptors.

ITPR2 ITPR3

3.00e-05219128081734
Pubmed

Sulphide signalling potentiates apoptosis through the up-regulation of IP3 receptor types 1 and 2.

ITPR1 ITPR2

3.00e-052191223582047
Pubmed

Novel homozygous mutations in the EVC and EVC2 genes in two consanguineous families segregating autosomal recessive Ellis-van Creveld syndrome.

EVC2 EVC

3.00e-052191226580685
Pubmed

ORP4L couples IP3 to ITPR1 in control of endoplasmic reticulum calcium release.

ITPR1 OSBP2

3.00e-052191231648575
Pubmed

Widening the mutation spectrum of EVC and EVC2: ectopic expression of Weyer variants in NIH 3T3 fibroblasts disrupts Hedgehog signaling.

EVC2 EVC

3.00e-052191219810119
Pubmed

Distinct activities of the alpha-catenin family, alpha-catulin and alpha-catenin, on beta-catenin-mediated signaling.

CTNNAL1 CTNNB1

3.00e-052191214993280
Pubmed

Investigation of -PRKACA/-PRKACB fusion genes in oncocytic tumors of the pancreatobiliary and other systems.

PRKACA PRKACB

3.00e-052191236152045
Pubmed

Distinct contributions of the innate immune receptors TLR2 and RP105 to formation and architecture of structured lung granulomas in mice infected with Mycobacterium tuberculosis.

TLR2 CD180

3.00e-052191236370035
Pubmed

Characterization of genomic clones coding for the C alpha and C beta subunits of mouse cAMP-dependent protein kinase.

PRKACA PRKACB

3.00e-05219122833513
Pubmed

Toll-like receptors 2 and 7 mediate coagulation activation and coagulopathy in murine sepsis.

TLR7 TLR2

3.00e-052191231211901
Pubmed

ATP binding to a unique site in the type-1 S2- inositol 1,4,5-trisphosphate receptor defines susceptibility to phosphorylation by protein kinase A.

ITPR1 PRKACA

3.00e-052191216621795
Pubmed

Growth factor regulation of estrogen receptor coregulator PELP1 functions via Protein Kinase A pathway.

PELP1 PRKACA

3.00e-052191218505929
Pubmed

Expression of IP3 receptor isoforms at the nodes of Ranvier in rat sciatic nerve.

ITPR2 ITPR3

3.00e-052191217496801
Pubmed

Mutational analysis of the ligand binding site of the inositol 1,4,5-trisphosphate receptor.

ITPR1 ITPR3

3.00e-05219128663526
Pubmed

Characterization of the Phosphorylation Site of GRTH/DDX25 and Protein Kinase A Binding Interface Provides Structural Basis for the Design of a Non-Hormonal Male Contraceptive.

PRKACA DDX25

3.00e-052191231040297
Pubmed

Sequencing EVC and EVC2 identifies mutations in two-thirds of Ellis-van Creveld syndrome patients.

EVC2 EVC

3.00e-052191217024374
InteractionTMT1A interactions

LRRC57 MBOAT7 TRPM7 APBB2 CCDC168 ITPR1 ITPR2 ITPR3 LRIG3 SLC12A2 GCC2 MACO1 SYNE2 ZRANB1 VPS13B GOLGB1

2.58e-0735918716int:TMT1A
InteractionMAGEA9 interactions

MYO9A GATB ITPR1 ITPR2 ITPR3 ZFHX4 SHPRH KIF14 RARS2 EIF2AK4 MTO1

4.05e-0620818711int:MAGEA9
InteractionCOIL interactions

KCNE3 NOP56 KALRN UVSSA CDK11A DDX56 CCT4 ICE1 ZNF780A CEBPZ UTP4 KIF14 KLHL8 ZRANB1 SNRNP200 TNPO3 RPL7A PCID2

4.13e-0655218718int:COIL
InteractionFBXO42 interactions

DOCK4 MYO9A CCT4 PPP6R1 RUFY1 ANAPC1 MACO1 KIF14 CTNNB1 RPL7A PCM1 GOLGB1

5.74e-0625918712int:FBXO42
InteractionELOVL5 interactions

MBOAT7 TRPM7 ITPR1 ITPR2 ITPR3 LRIG3 SLC12A2 GCC2 MACO1 SYNE2 SLC39A14 ZRANB1 VPS13B GOLGB1

8.14e-0636418714int:ELOVL5
InteractionSEPTIN10 interactions

HK2 CEP350 IGF1R GCC2 ZRANB1 IMMT PCM1 GOLGB1 SEPTIN12

8.15e-061441879int:SEPTIN10
InteractionRPGRIP1L interactions

PPP1R21 IPO8 DDX56 TRIM27 CEP350 UTP4 CEP135 NINL KIF14 RPP25L PCM1

8.56e-0622518711int:RPGRIP1L
InteractionATG16L1 interactions

IPO8 RBBP7 APBB2 DDX56 CCDC168 PPP6R1 TRIM27 RUFY1 ITPR1 ITPR2 ITPR3 CEP350 APPL2 GCC2 TLR2 BRD9 MRPS9 KIF14 TRAF3IP3 CORO7 NNMT ZRANB1 IMMT RPL7A PCID2 PCM1 GOLGB1

9.70e-06116118727int:ATG16L1
InteractionNUP155 interactions

EVC2 MBOAT7 TRPM7 ITPR1 ITPR2 ITPR3 IGF1R GCC2 MACO1 SYNE2 CEP135 KIF14 ZRANB1 RPL7A VPS13B GOLGB1

1.02e-0547718716int:NUP155
InteractionDNAJC25 interactions

NOP56 MBOAT7 PPP6R1 ITPR1 ITPR2 ITPR3 SLC12A2 MACO1 SYNE2 IMMT RPL7A VPS13B

1.45e-0528418712int:DNAJC25
InteractionEMD interactions

EVC2 MBOAT7 TRPM7 UVSSA PPEF1 RUFY1 ITPR1 ITPR2 ITPR3 KIF9 IGF1R SLC12A2 MACO1 SYNE2 PRKACA CEP135 TRAF3IP3 CTNNB1 ZRANB1 SNRNP200 VPS13B

1.46e-0578918721int:EMD
InteractionHSD3B7 interactions

APPBP2 LRRC57 MBOAT7 TRPM7 ITPR1 ITPR2 ITPR3 SLC12A2 GCC2 MACO1 SYNE2 SLC39A14 MGAT5B GOLGB1

1.57e-0538618714int:HSD3B7
InteractionPCNT interactions

IPO8 KALRN RBBP7 CEP350 UTP4 PRKACA CEP135 NINL KIF14 ZRANB1 PCM1

1.63e-0524118711int:PCNT
InteractionCOMTD1 interactions

CAB39 SETX IPO8 PPP6R1 HEATR1 MSTO1 INTS4 SLC39A14 ZRANB1 TNPO3

1.82e-0520018710int:COMTD1
InteractionEFNB1 interactions

SETX IPO8 RNF213 HEATR1 MSTO1 KRBA1 SLC12A2 SACS INTS4 KIF14 TNPO3

2.75e-0525518711int:EFNB1
InteractionGJA1 interactions

CTNNAL1 KALRN TRPM7 APBB2 ITPR2 ITPR3 LRIG3 IGF1R SLC12A2 ARHGEF10 GCC2 MACO1 SYNE2 CTNNB1 SLC39A14 VPS13B GOLGB1

3.24e-0558318717int:GJA1
InteractionNDC80 interactions

TRPM7 ICE1 DSN1 CEP350 GCC2 SYNE2 CEP135 KIF14 NHS CEP295 ZRANB1 PCM1

3.66e-0531218712int:NDC80
InteractionANPEP interactions

LRRC57 TRPM7 ITPR3 LRIG3 SYNE2 SLC39A14 ZRANB1 IMMT GOLGB1

3.69e-051741879int:ANPEP
InteractionCCDC8 interactions

KCNE3 NOP56 RBBP7 PACSIN3 HEATR1 ITPR2 ITPR3 CEP350 SLC12A2 SACS PRKACA CTNNB1 ZRANB1 SNRNP200 IMMT RPL7A PCM1 GOLGB1

4.18e-0565618718int:CCDC8
InteractionB3GAT1 interactions

MBOAT7 TRPM7 APBB2 ITPR1 ITPR2 ITPR3 SLC12A2 GCC2 MACO1 SYNE2 SLC39A14 VPS13B GOLGB1

5.35e-0537718713int:B3GAT1
InteractionNOLC1 interactions

NOP56 CDK11A RNF213 DDX56 PELP1 CEBPZ UTP4 BRD9 PRKACA KIF14 ZRANB1 RPL7A

5.43e-0532518712int:NOLC1
InteractionRAC2 interactions

CTNNAL1 MBOAT7 TRPM7 DDX56 RUFY1 ITPR1 ITPR3 SLC12A2 MACO1 SYNE2 PRKACB KIF14 NHS CTNNB1 SLC39A14 IMMT VPS13B GOLGB1

5.92e-0567418718int:RAC2
InteractionRND2 interactions

MBOAT7 TRPM7 DDX56 RUFY1 ITPR1 SLC12A2 MACO1 SYNE2 KIF14 CTNNB1 SLC39A14 IMMT VPS13B GOLGB1

6.56e-0544018714int:RND2
InteractionRASEF interactions

PPFIBP2 ITPR1 ITPR2 ITPR3

7.80e-05251874int:RASEF
InteractionSIGLECL1 interactions

SETX IPO8 MBOAT7 RNF213 INTS4 KIF14 TNPO3

8.93e-051131877int:SIGLECL1
InteractionPKD2L2 interactions

SEMG1 TRPM7 ITPR3

1.23e-04111873int:PKD2L2
InteractionRAB9A interactions

KCNE3 MBOAT7 TRPM7 APBB2 RUFY1 ITPR2 ITPR3 SLC12A2 GCC2 MACO1 SYNE2 SLC39A14 IMMT VPS13B GOLGB1 MCOLN2

1.43e-0459518716int:RAB9A
InteractionUSP36 interactions

DOCK4 NOP56 DHX57 DDX56 CCT4 HEATR1 CEP350 PELP1 CEBPZ UTP4 SHPRH KIF14 CTNNB1 ZRANB1 IMMT RPL7A

1.54e-0459918716int:USP36
InteractionTAFA4 interactions

APPBP2 ITPR1 ITPR2 ITPR3 SORL1

1.56e-04551875int:TAFA4
InteractionMCM10 interactions

DCAF1 KCNE3 NOP56 ORC4 NINL ZRANB1 PCM1

1.60e-041241877int:MCM10
InteractionCCDC85C interactions

APPBP2 CEBPG OSBPL7 NINL CTNNB1 ZRANB1 PCM1

1.68e-041251877int:CCDC85C
InteractionNEK2 interactions

SEMG1 KCNE3 TRIM27 ANAPC1 PDE4DIP CTNNB1 IMMT

1.85e-041271877int:NEK2
InteractionLAMP3 interactions

MBOAT7 TRPM7 RNF213 HEATR1 ITPR2 ITPR3 APPL2 SLC12A2 GCC2 MACO1 SYNE2 INTS4 SLC39A14 GOLGB1

1.86e-0448618714int:LAMP3
InteractionERGIC1 interactions

MBOAT7 TRPM7 ITPR2 ITPR3 SLC12A2 MACO1 SYNE2 KIF14 SLC39A14 GOLGB1

1.86e-0426418710int:ERGIC1
InteractionUSO1 interactions

DNAH2 CCDC168 RUFY1 PDE4DIP PRKACA SPOP CTNNB1 ZRANB1 GOLGB1

1.87e-042151879int:USO1
InteractionDISC1 interactions

NOP56 KALRN PPP6R1 TRIM27 CEP350 CCDC13 KIF9 PDE4DIP RNF20 ZRANB1 IMMT PCM1 SORL1

1.94e-0442918713int:DISC1
InteractionSIRT7 interactions

DCAF1 NOP56 RBBP7 DHX57 DDX56 HEATR1 ITPR3 PELP1 CEBPZ ANAPC1 UTP4 SYNE2 KIF14 ZRANB1 SNRNP200 IMMT RPL7A PCM1

2.03e-0474418718int:SIRT7
InteractionTACSTD2 interactions

DCAF1 SETX RNF213 SACS INTS4 KIF14 TNPO3

2.04e-041291877int:TACSTD2
GeneFamilyInositol 1,4,5-triphosphate receptors|Protein phosphatase 1 regulatory subunits

ITPR1 ITPR2 ITPR3

2.85e-0731203297
GeneFamilyBasic leucine zipper proteins|CCAAT/enhancer binding proteins

CEBPG CEBPZ

6.44e-04612021165
CoexpressionGSE21546_ELK1_KO_VS_SAP1A_KO_AND_ELK1_KO_ANTI_CD3_STIM_DP_THYMOCYTES_UP

VWA3A EVC2 SETX UVSSA MSTO1 LURAP1L SLC12A2 SHPRH RPP25L VPS13B

1.70e-0619918610M7530
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

DOCK4 APPBP2 SETX MAN2A1 ATRX APBB2 ITPR1 CEP350 IGF1R SACS ARHGEF10 GCC2 SYNE2 CEP135 PRKACB KIF14 SPOP DENND5A VPS13B CCDC93

3.26e-0685618620M4500
CoexpressionHAMAI_APOPTOSIS_VIA_TRAIL_UP

CTNNAL1 SETX MYO9A ITPR1 ITPR2 CEP350 SACS CEBPZ GCC2 SYNE2 RNF20 SNX10 KIF14 RORA PCM1 GOLGB1 SORL1

4.83e-0665618617M18979
CoexpressionGSE27786_LIN_NEG_VS_BCELL_DN

PPP1R21 DHX57 GCC2 SYNE2 PDE4DIP SPOP TRAF3IP3 RPP25L MGAT5B

1.38e-052001869M4768
CoexpressionGSE34515_CD16_POS_MONOCYTE_VS_DC_DN

CAB39 TLR7 KANSL2 MCTP1 APPL2 TLR2 PLAGL2 CEP295 DENND5A

1.38e-052001869M8763
CoexpressionGSE3920_IFNA_VS_IFNB_TREATED_ENDOTHELIAL_CELL_UP

TMEM176A IGF1R APPL2 IKBKE SYNE2 PRKACB RORA KCNH5

2.92e-051691868M6700
ToppCellCF-Myeloid-Neutrophil|CF / Disease state, Lineage and Cell class

DOCK4 TBC1D2 DYSF LIF MCTP1 TLR2 PLAU TRAF3IP3 DENND5A SORL1

5.57e-0918318610da43827952e6fdee2ce94648c316182f272b321c
ToppCellCF|World / Disease state, Lineage and Cell class

DOCK4 MBOAT7 ISG20 DYSF LIF IGF1R SYNE2 TLR2 PLAU TRAF3IP3

6.86e-0918718610eec4d4e4a658e3a61c05745167a1a5e3d39bb43e
ToppCellsystemic_lupus_erythematosus-flare|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

ACAP1 SETX ATRX RNF213 ISG20 GCC2 SYNE2 RORA TRAF3IP3 PCM1

1.18e-08198186104c93ee921d56132d80832d8e94563f32ccf13bbc
ToppCellmild-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

BNC2 ATRX CDK11A RNF213 SYNE2 RORA SNRNP200 VPS13B PCM1 GOLGB1

1.24e-0819918610f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCellCV-Severe-7|CV / Virus stimulation, Condition and Cluster

MAN2A1 DPY19L2 KALRN RNF213 HEATR1 ZBED6 OSBP2 SLC39A14 PCM1

5.82e-0817618693de0c7d77210049e5616db21eed1490a17a5ec2d
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KCNH7 DPY19L2 TRPM7 APBB2 ITPR1 SLC12A2 SNX10 UNC13C SORL1

8.13e-0818318692e831a4d99c6f983793df71c0994124c943c6da9
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

BNC2 LIF SYNE2 SNX10 NINL NHS PLAU NNMT MGAT5B

1.07e-0718918698c8ca3b30d9be6c854615459a7bfba82b427c8bc
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

BNC2 LIF SYNE2 SNX10 NINL NHS PLAU NNMT MGAT5B

1.07e-0718918695d902a4660a27548764bf04c6de152b565da835c
ToppCell(1)_T_cells-(1)_T_CD4_naive|(1)_T_cells / Spleen cell shreds - cell class (v1) and cell subclass (v1)

ATRX ATP8B2 IGF1R ZBED6 GCC2 SHPRH NHS CA6 SORL1

1.40e-071951869d3fa551bc6f5ee5890af1040415e61ecd5d46201
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

ACAP1 RNF213 ISG20 SYNE2 PRKACB RORA TRAF3IP3 PCM1 CA6

1.52e-0719718692e9677b4b9a7c88db16416e5f114a2031ec3bc24
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

VWA3A CFAP47 DPY19L2 DNAH2 CCDC39 CFAP54 SYNE2 C6 LRRC74B

1.52e-07197186974a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCellMild|World / Condition, Lineage, Cell class and cell subclass

ATRX KALRN CEP350 GCC2 PRKACB SPOP TRAF3IP3 GOLGB1 MCOLN2

1.52e-071971869476b0d0389f9fcd4614f6bb1f494281f467f6730
ToppCellCOVID-19_Moderate|World / disease group, cell group and cell class

ACAP1 ATRX CDK11A RNF213 ISG20 CEBPZ GCC2 SYNE2 RORA

1.66e-071991869952fac67588ad5676f5939e3c7f8bac803c27064
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KCNH7 DPY19L2 TRPM7 APBB2 ITPR1 SLC12A2 SNX10 NHS

3.83e-0716018688bcdbcfdf1e0ace6053e8de82762f6e2f86bba7a
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KCNH7 DPY19L2 TRPM7 APBB2 ITPR1 SLC12A2 SNX10 NHS

3.83e-0716018682d391ba6f7adb55dfa89feecc10cc9ce97e5fe74
ToppCellnormal_Pleural_Fluid-Myeloid_cells-CD163+CD14+_DCs|Myeloid_cells / Location, Cell class and cell subclass

ANGPT2 PACSIN3 ATP8B2 FSIP2 CFAP54 KANSL2 SYNE2 RORA

5.80e-071691868bea8aba1f3cc3d0e8d448c1c45f5354d26ebf850
ToppCellCTRL-Myeloid-Neutrophil|Myeloid / Disease state, Lineage and Cell class

MBOAT7 ISG20 DYSF IGF1R SYNE2 TLR2 TRAF3IP3 SORL1

6.07e-071701868151dabe1d240dde414c881bf4fa816c69fa1c32d
ToppCelldroplet-Fat-SCAT-30m-Lymphocytic-T_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACAP1 TMEM176A ITPR3 LIF KRBA1 NEK8 RORA TRAF3IP3

8.23e-071771868baf78a8dad55f124f56585f88b10b58c0269680f
ToppCellControl-Epithelial_cells-Airway_ciliated|Control / group, cell type (main and fine annotations)

VWA3A CFAP47 DNAH2 CCDC39 CCDC13 CFAP54 C6 BBOF1

1.02e-061821868fb725d10d9ed25dfc6d5bb69cfef78513f7d3e8f
ToppCellAdult-Epithelial-ciliated_cell-D122|Adult / Lineage, Cell type, age group and donor

VWA3A CFAP47 DNAH2 CCDC13 CFAP54 C6 LRRC74B BBOF1

1.02e-0618218687ded554a4b441e6496db673ba206c0d76ccad7d9
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

BNC2 MYO9A EVC CFAP54 SYNE2 SNX10 NHS NNMT

1.24e-061871868c31130fc2f9f882944b2ba366a034a03f051c4b9
ToppCell(1)_T_CD4_naive|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)

ACAP1 ATP8B2 GCC2 SYNE2 RORA TRAF3IP3 CA6 SORL1

1.30e-061881868b8f67ac2faadd5b848955e43ab5d6cf5e49b3681
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

TRPM7 RNF213 ITPR1 ZBED6 SYNE2 RORA CTNNB1 GOLGB1

1.30e-061881868ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCellLA-14._Fibroblast_III|LA / Chamber and Cluster_Paper

BNC2 LIF PAPPA RORA PLAU DENND5A SLC39A14 NNMT

1.58e-0619318687426c291bac59e539c427bcaae18abc7d397d44e
ToppCellCF-Myeloid|CF / Disease state, Lineage and Cell class

DOCK4 MBOAT7 DYSF MCTP1 TLR2 PLAU DENND5A SORL1

1.70e-061951868ecf604de496f389a49429d0bb211e1db6019cc8b
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CTNNAL1 KCNH7 TRPM7 APBB2 ITPR1 SLC12A2 SNX10 UNC13C

1.70e-061951868a38d9dc6192aea673d96fda6b25e81223fda3abf
ToppCellCOVID_non-vent-Lymphocytic|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

ACAP1 ISG20 ATP8B2 GCC2 SYNE2 PRKACB RORA TRAF3IP3

1.84e-061971868c672915f8c8c1e948d251f6eaf9f84a5600c1193
ToppCellCOVID_vent-Lymphocytic-T_cell|COVID_vent / Disease condition, Lineage, Cell class and subclass

ACAP1 ATP8B2 GCC2 SYNE2 PRKACB RORA TRAF3IP3 SORL1

1.84e-061971868ad702e440a74d54cfdcb8bb1c66bd8e0e71ab04e
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

ACAP1 RNF213 ISG20 SYNE2 PRKACB RORA TRAF3IP3 PCM1

1.84e-0619718684c9919914079e76b1d2220b249e0d0b0d9bf4bc0
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ACAP1 ISG20 ATP8B2 GCC2 SYNE2 PRKACB RORA TRAF3IP3

1.84e-06197186859b1fb93a39dcf8c994d2b7dc2906dae74c57527
ToppCellH1299-infected-SARSCoV2|infected / Cell line, Condition and Strain

NOP56 ATRX CEP350 PELP1 BRD9 CEP295 TNPO3 GOLGB1

1.84e-0619718680fa3e4cf93e77d78b1f97b906c5b13ca741ae17e
ToppCellSepsis-Leuk-UTI-Lymphocyte-T/NK-CD4+_CTL|Leuk-UTI / Disease, condition lineage and cell class

ACAP1 PACSIN3 SYNE2 OTUD7A PAPPA RORA OSBP2 TPBG

1.98e-061991868b2609f9d716fdd04f35f0da7f8995d28d7df431d
ToppCellhealthy_donor-Lymphocytic|healthy_donor / Disease condition, Lineage, Cell class and subclass

ACAP1 RNF213 ISG20 ATP8B2 SYNE2 PRKACB RORA TRAF3IP3

1.98e-0619918682841e16d54acd344ba454f024e285c28abc37319
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_ciliated-Ciliated|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

VWA3A CFAP47 DNAH2 CCDC13 CFAP54 C6 LRRC74B BBOF1

2.06e-062001868926a7ea94b5908aebf103893ea83ce9d25285b65
ToppCellTracheal-NucSeq-Stromal-Chondrocytic-Chondrocyte|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

BNC2 DPY19L2 ATP8B2 CFAP54 PDE4DIP ITIH6 NNMT MCOLN2

2.06e-062001868f5bd0b30e478dac09f68c46b0781f5f2e7e3c693
ToppCellBiopsy_IPF-Epithelial-Ciliated|Biopsy_IPF / Sample group, Lineage and Cell type

VWA3A CFAP47 DNAH2 CCDC39 KIF9 CFAP54 C6 BBOF1

2.06e-062001868bb8c99156e547a8eb6599b6b6bc3c66bf77af7f8
ToppCellLPS_IL1RA-Endothelial-Endothelial-Activated_Alv_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

JCAD CTNNAL1 SETX RNF213 MCTP1 SLC12A2 ARHGEF10 SYNE2

2.06e-06200186879e51afb57ca38aacebd0298e5e727b55c0cfff9
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_ciliated|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

VWA3A CFAP47 DNAH2 CCDC13 CFAP54 C6 LRRC74B BBOF1

2.06e-06200186806ce6e03498ba38ef6a06eaf2731e3b2eeda59eb
ToppCellTracheal-NucSeq-Stromal-Chondrocytic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

BNC2 DPY19L2 ATP8B2 CFAP54 PDE4DIP ITIH6 NNMT MCOLN2

2.06e-062001868b5a54b9baf79aea01f76a161f0a39bbe87eb4945
ToppCellParenchymal-10x3prime_v2-Immune_Myeloid-Myeloid-Megakaryocyte|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

MBOAT7 FAM200A PARVG ITPR1 LIF SNX10 PRKACB ADAT1

2.06e-0620018680d76b006d8e8b32174e65e400acd0674354b962c
ToppCellParenchymal-10x3prime_v2-Immune_Myeloid-Myeloid|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

MBOAT7 FAM200A PARVG ITPR1 LIF SNX10 PRKACB ADAT1

2.06e-062001868cc8368665bc6bb7c4f39632ccff07ceaa98a7b65
ToppCellLeuk-UTI-Lymphocyte-T_NK-CD4_CTL|Leuk-UTI / Disease, Lineage and Cell Type

ACAP1 PACSIN3 SYNE2 PAPPA RORA OSBP2 TPBG

3.92e-061541867170a421fd69dba2929568c72e983ae9cfaf2aabc
ToppCellHealthy_Control-Myeloid-Macrophages-|Healthy_Control / Condition, Lineage, Cell class and cell subclass

ACAP1 KCNH7 ISG20 ATP8B2 SYNE2 RORA TRAF3IP3

5.26e-061611867d0482666479530cd2fd0d229cbb59a1d79839477
ToppCellMild-Lymphoid-NK-innate_T|Mild / Condition, Lineage, Cell class and cell subclass

ACAP1 KRBA1 OSBPL7 NHS TRAF3IP3 SLC39A14 SORL1

5.47e-061621867bd218e41b2eadc3bba4c7ac3e34a014f6ad8b1bf
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c06-NR4A2|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

EVC2 RBBP7 CDK11A HEATR1 CEBPZ SYNE2 RORA

5.47e-06162186780317c4253bf8e897782e562f29835f181c65b98
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CTNNAL1 DPY19L2 APBB2 ITPR1 SLC12A2 UNC13C SORL1

5.47e-06162186736ddebe3bb172c992739353b7b049b2dde98b559
ToppCellNS-control-d_0-4-Myeloid-pDC|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CCDC168 TLR7 ITPR1 PHEX TGFBI CD180 MCOLN2

6.17e-0616518678b2d43d7c4ee07bd999bd51bc15117ce1fbb2d86
ToppCellcontrol-Myeloid-pDC|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

CCDC168 TLR7 ITPR1 PHEX TGFBI CD180 MCOLN2

6.17e-061651867243c74adf8d993ff92acbff2768bdc5a1693eca3
ToppCellCiliated_cells-B-Donor_08|World / lung cells shred on cell class, cell subclass, sample id

VWA3A CFAP47 DNAH2 CCDC39 CFAP54 C6 BBOF1

6.42e-0616618674b1056aad8a99827835242b8ab0c7f2bb84471f1
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c03-GZMK|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

PCSK2 DNAH2 ITPR3 PRKACB NNMT ADAT1 MCOLN2

6.68e-061671867063ec29b32e40aaa138a691da3a79ee8eef0c2be
ToppCellBAL-Control-Lymphocyte-T/NK-NK_cell-NK-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

JCAD ACAP1 DPY19L2 CDHR1 LIF SYNE2 KCNMB4

7.22e-061691867e9c0e0f4c421c7bdbf1a7e33002f3cf22ea307cb
ToppCellBAL-Control-Lymphocyte-T/NK-NK_cell|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

JCAD ACAP1 DPY19L2 CDHR1 LIF SYNE2 KCNMB4

7.22e-061691867d375a1df1ecc938f66bad92e54b8cda26ca9c472
ToppCellBAL-Control-Lymphocyte-T/NK-NK_cell-NK|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

JCAD ACAP1 DPY19L2 CDHR1 LIF SYNE2 KCNMB4

7.22e-06169186758f805c0be507bd5fadc9ea3555032daabbc8ab8
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

VWA3A DNAH2 TDRD1 CCDC13 CFAP54 LRRC74B BBOF1

7.22e-06169186714aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_T-T4_reg-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

ACAP1 ISG20 GCC2 SYNE2 RORA TRAF3IP3 PCM1

8.10e-0617218679497948bbe53fb88c6ff6b347f743d456da587e5
ToppCellCTRL-Myeloid-Neutrophil|CTRL / Disease state, Lineage and Cell class

MBOAT7 ISG20 DYSF SYNE2 TLR2 TRAF3IP3 SORL1

8.10e-061721867ef3a6fe3b7300959f9f71130200c7fb8741c42b0
ToppCellPND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

BNC2 PPFIBP2 RNF112 GBX1 SYNE2 PAPPA UNC13C

8.42e-06173186730d67738633493d47f06ae452424382f069b6c0a
ToppCellPND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

BNC2 PPFIBP2 RNF112 GBX1 SYNE2 PAPPA UNC13C

8.74e-061741867a9c6edf5c3fc119c24425f921c5566a8356c30fe
ToppCellMultiple_Sclerosis-Lymphocyte-T_NK-CD4_TEM|Multiple_Sclerosis / Disease, Lineage and Cell Type

ACAP1 ISG20 PPEF1 SYNE2 RORA TRAF3IP3 TPBG

8.74e-061741867d2ea5b55bf03a8013816d073896208f311c3e544
ToppCellCV-Severe-7|Severe / Virus stimulation, Condition and Cluster

MAN2A1 KALRN RNF213 ZBED6 OSBP2 SLC39A14 PCM1

9.77e-06177186782fdd6185b368f54f03de389427cbe3071d21a99
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic_T-T4_reg-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

ACAP1 ISG20 ATP8B2 GCC2 SYNE2 RORA TRAF3IP3

1.01e-05178186790dedb3cef9b01907b9f8eec64218d6d2072be1f
ToppCellHealthy_Control-Lymphoid-NK-NK|Healthy_Control / Condition, Lineage, Cell class and cell subclass

JCAD ACAP1 DPY19L2 CDHR1 ISG20 LIF TRAF3IP3

1.01e-05178186771e99f143009b2d29cb47b96393b58b514c8cfc6
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic_T-T4_reg|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

ACAP1 ISG20 ATP8B2 GCC2 SYNE2 RORA TRAF3IP3

1.01e-051781867d6312286bf6cc5b107ccd7adb583d9667d4e1d21
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KCNH7 DPY19L2 TRPM7 APBB2 ITPR1 SLC12A2 SNX10

1.13e-051811867e0abf2707d9e0aa942c657eef7d2cbcd02f060dd
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KCNH7 DPY19L2 TRPM7 APBB2 ITPR1 SLC12A2 UNC13C

1.17e-0518218675f513bbb7125956eb528e3120de3fd776770a7c3
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KCNH7 DPY19L2 TRPM7 APBB2 ITPR1 SLC12A2 UNC13C

1.21e-0518318672f0ee40e69ad1259e56e8ee4b352736900eb8901
ToppCellHealthy_Control-Lymphoid-NK|Healthy_Control / Condition, Lineage, Cell class and cell subclass

JCAD ACAP1 CDHR1 ISG20 LIF SYNE2 TRAF3IP3

1.21e-051831867b41b1f32022c8632a638cf1c5523c9a24176f568
ToppCellLPS-IL1RA|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DOCK4 EVC2 CTNNAL1 CEBPG DYSF MCTP1 SLC39A14

1.26e-051841867c066c2ec4f0f1d6eb183fca5c7bb0cd45c9950dc
ToppCellChildren_(3_yrs)-Epithelial-ciliated_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

VWA3A CFAP47 DPY19L2 DNAH2 CCDC13 CFAP54 LRRC74B

1.26e-0518418675daff849625f2f41d56615569c0ed59cd733b34c
ToppCellTCGA-Uvea-Primary_Tumor-Uveal_Melanoma-Epithelioid_Cell-4|TCGA-Uvea / Sample_Type by Project: Shred V9

DOCK4 MAN2A1 CEBPG IDE ITPR2 LURAP1L VPS13B

1.26e-0518418679c56753e5e668be888662e4713cf4ce44e6c58fb
ToppCellCiliated_cells-B-IPF_02|World / lung cells shred on cell class, cell subclass, sample id

VWA3A DNAH2 CCDC39 CFAP54 C6 LRRC74B BBOF1

1.30e-0518518674fc7113d3dadc716ec5a8e62b58543cc00ce5b16
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MAN2A1 ITPR3 KRBA1 NEK8 TLR2 KCNMB4 SMC1B

1.30e-05185186787151ab95530e70d61328b336518df58db584acb
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic_T-CD4-positive,_alpha-beta_T_cell-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

ACAP1 ISG20 GCC2 SYNE2 RORA TRAF3IP3 MTO1

1.30e-051851867406b52516b26e9fe2c9e768950af447ec7ad5f3e
ToppCellAdult-Epithelial-ciliated_cell-D175|Adult / Lineage, Cell type, age group and donor

VWA3A CFAP47 DNAH2 CCDC13 CFAP54 C6 BBOF1

1.30e-05185186730f4980dee6cd5959655f8d74049f3bfb5312611
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic_T-CD4-positive,_alpha-beta_T_cell|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

ACAP1 ISG20 GCC2 SYNE2 RORA TRAF3IP3 MTO1

1.30e-051851867f2ebd099c8dfcfaca4298bcdd618c50701a9c2c8
ToppCellNS-moderate-d_07-13-Epithelial-Ciliated|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

VWA3A CFAP47 DNAH2 CCDC39 CCDC13 CFAP54 BBOF1

1.35e-05186186785787ff207f109ec7e3c0f729ba9bda739c2fdc9
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MYO9A EVC CFAP54 SYNE2 SNX10 NHS NNMT

1.35e-051861867f0c8de4f6ae9047b9108a47a2af8c5f42bc103b0
ToppCelldroplet-Heart-nan-3m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK4 JCAD ATRX ITPR2 CEP350 SACS SYNE2

1.35e-0518618670ae5fbe9f210cb25092394267e1d3d6ed05627b8
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1|TCGA-Pancreas / Sample_Type by Project: Shred V9

SETX ATRX IDE CEP350 GCC2 CEP295 VPS13B

1.35e-05186186703db813598b67b1e08f759758a1c2023396921fa
ToppCellMesenchymal_cells-Adipo-CAR|World / Lineage and Cell class

ANGPT2 APBB2 TMEM176A ISLR AGT PAPPA NNMT

1.35e-0518618676ca8ce7ced91d6308b7c056032ffec1b37c974bf
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

BNC2 MYO9A EVC SYNE2 SNX10 NHS NNMT

1.44e-051881867af740fa78542438fdff627ea1f74f4eee43316be
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic_T-CytoT_GZMK+-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

ACAP1 RNF213 ISG20 GCC2 SYNE2 RORA TRAF3IP3

1.49e-051891867f1129eb122bbc051457c5545f1a267beb988b0f2
ToppCellASK428-Epithelial-Transformed_epithelium|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq

BNC2 EVC2 TMEM176A LIF ZFHX4 PAPPA TPBG

1.49e-05189186787189275234b5d59484c58acbb14a09903f2b578
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic_T-CytoT_GZMK+|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

ACAP1 RNF213 ISG20 GCC2 SYNE2 RORA TRAF3IP3

1.49e-0518918670b012ee301419fa9ccc387c3ff66c2344b349a97
ToppCellBAL-Control-Myeloid-MoAM-MoAM1|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

DOCK4 TMEM176A DYSF TGFBI PLAU UNC13C CD180

1.49e-051891867ebb5e069fdca7cf8ffac16a57572e92d2593c86a
ToppCellAdult-Epithelial-ciliated_cell|Adult / Lineage, Cell type, age group and donor

VWA3A CFAP47 DNAH2 CFAP54 C6 LRRC74B BBOF1

1.49e-051891867b679920f0993e917dd86da082113bfbd85ea1ca5
ToppCellBAL-Control-Myeloid-MoAM-MoAM1-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

DOCK4 TMEM176A DYSF TGFBI PLAU UNC13C CD180

1.49e-051891867a59e4eaff430a443f9fa7edabe64e66a15b6bffb
ToppCellcritical-Epithelial-Ionocyte|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

BNC2 MAN2A1 DPY19L2 ITPR2 UNC13C RINL CA6

1.55e-05190186705a2c3549b68f49081723bf35db14974274419d5
ToppCell5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-CD8-positive,_alpha-beta_T_cell-CD8_T_cells-CD8_T_cells_L.1.1.4.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ACAP1 RNF213 SYNE2 PRKACB RORA TRAF3IP3 LGR6

1.55e-051901867d153a0bdedcd6865e6ee19575234a78b5d859ff1
ToppCellBAL-Control-Myeloid-MoAM-MoAM1|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DOCK4 TMEM176A DYSF TGFBI PLAU UNC13C CD180

1.55e-0519018674b4fe93061c87605dddf5bec94fa07c749c722aa
ToppCellBAL-Control-Myeloid-MoAM-MoAM1-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DOCK4 TMEM176A DYSF TGFBI PLAU UNC13C CD180

1.55e-0519018675c8aa310886c64ee5dce4ba46a3dd178da549529
ToppCellCiliated_cells-B|World / lung cells shred on cell class, cell subclass, sample id

VWA3A DNAH2 CCDC39 CFAP54 C6 LRRC74B BBOF1

1.55e-0519018677031fbedc13be1a00f6333ad6d51849c3739c2e6
ToppCellEpithelial_cells-Ciliated_cells-B|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id

VWA3A DNAH2 CCDC39 CFAP54 C6 LRRC74B BBOF1

1.55e-051901867426a4806f6e39d4d57c6746609d30bb3ca62df7d
ToppCellPCW_13-14|World / Celltypes from embryonic and fetal-stage human lung

DOCK4 UVSSA LURAP1L LRIG3 IGF1R RORA UNC13C

1.55e-05190186762a3ec1ae0829602b0569cc051210551644f1d46
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HK2 ATRX ZFHX4 ZBED6 RORA PLAU PCM1

1.60e-0519118677d1595e616f6f111fc2f5bc1b179c5d67d624cc9
ToppCellLPS_only-Endothelial-Endothelial-Activated_Alv_Cap|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CTNNAL1 KCNH7 ANGPT2 APBB2 DYSF MCTP1 SLC12A2

1.60e-051911867a7b18bcf27c38ad2353c239ecb309c80f3ef3359
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Myeloid-Monocytic-Classical_Monocyte-Mono_c1-CD14-CCL3|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

KCNE3 TMEM176A DYSF TGFBI MCTP1 TLR2 SNX10

1.60e-0519118679f0d956e9a14b1cd2c20a52639c6b22c349b377e
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_adventitial_fibro_(10)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

PCSK2 BNC2 KCNH7 ISLR PHEX ZFHX4 TPBG

1.60e-051911867156b467187331ac6ca390d6ca861d9670bb7b956
ToppCellHealthy_Control-Lymphoid-T-CD8_T|Healthy_Control / Condition, Lineage, Cell class and cell subclass

ACAP1 ISG20 ATP8B2 SYNE2 OTUD7A RORA TRAF3IP3

1.65e-05192186736b6ea21b0b1342f2dcac4dcaf359b6c772203f7
ToppCellfacs-Aorta-Heart-3m|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CAB39 LRRC8C JCAD ATRX CEP350 PRKACB CTNNB1

1.65e-0519218671ccc47792edf9ee23501c8e2165d11271636b66a
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

SETX ATRX CEP350 GCC2 SYNE2 RORA GOLGB1

3.26e-07491017GAVISH_3CA_METAPROGRAM_CD8_T_CELLS_CHROMATIN
ComputationalNeighborhood of RFC4

CDK11A CCT4 ICE1 CEBPZ KIF14 SNRNP200 IMMT TNPO3

8.44e-051511018MORF_RFC4
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

ATRX RNF213 GCC2 SYNE2 TRAF3IP3

1.00e-04501015GAVISH_3CA_METAPROGRAM_CD8_T_CELLS_UNASSIGNED_1
ComputationalNeighborhood of BUB1B

CDK11A CEBPZ KIF14 PLAGL2 IMMT

3.76e-04661015MORF_BUB1B
DrugMagnetite Nanoparticles

LRRC8C ACAP1 ANGPT2 ATRX TRPM7 PPFIBP2 RNF213 TLR7 ISG20 IDE ITPR1 ITPR2 TGFBI LIF IGF1R ZFHX4 SACS IKBKE ANAPC1 AGT TLR2 PDE4DIP DDX25 PAPPA PLAGL2 PLAU NNMT MGAT5B ZRANB1 ADAT1 PCM1 TPBG MCOLN2 SORL1

2.11e-09131018734ctd:D058185
DrugSuccimer

LRRC8C ACAP1 ANGPT2 ATRX TRPM7 PPFIBP2 RNF213 TLR7 ISG20 IDE ITPR1 ITPR2 LIF IGF1R ZFHX4 SACS IKBKE ANAPC1 AGT PDE4DIP PAPPA PLAGL2 PLAU NNMT MGAT5B ZRANB1 ADAT1 PCM1 TPBG MCOLN2 SORL1

4.40e-08126418731ctd:D004113
Drugprochlorperazine dimaleate salt; Up 200; 10uM; MCF7; HT_HG-U133A

DCAF1 BNC2 ISG20 UBOX5 ITPR1 AGT TLR2 PDE4DIP PAPPA PLAU C6

5.76e-07192187115575_UP
DrugAmethopterin (R,S) [59-05-2]; Up 200; 8.8uM; MCF7; HT_HG-U133A

DCAF1 MBOAT7 PPFIBP2 DNAH2 UBOX5 LIF IKBKE PLAU TRAF3IP3 VPS13B

5.36e-06196187105000_UP
Druggeldanamycin

CAB39 SETX IPO8 ATRX HEATR1 APPL2 ZFHX4 ZBED6 PDE4DIP PAPPA PLAU CTNNB1 PCM1

1.30e-0537118713ctd:C001277
DiseaseEllis-van Creveld syndrome

EVC2 EVC

3.78e-0521822cv:C0013903
Diseasefibrolamellar carcinoma (is_implicated_in)

PRKACA CTNNB1

3.78e-0521822DOID:5015 (is_implicated_in)
DiseaseELLIS-VAN CREVELD SYNDROME

EVC2 EVC

3.78e-0521822225500
DiseaseEllis-Van Creveld syndrome (implicated_via_orthology)

EVC2 EVC

3.78e-0521822DOID:12714 (implicated_via_orthology)
DiseaseWeyers acrofacial dysostosis (is_implicated_in)

EVC2 EVC

3.78e-0521822DOID:0111571 (is_implicated_in)
DiseaseHypoxic Brain Damage

ITPR1 ITPR2

3.78e-0521822C1140716
DiseaseWEYERS ACROFACIAL DYSOSTOSIS

EVC2 EVC

3.78e-0521822193530
DiseaseCurry-Hall syndrome

EVC2 EVC

3.78e-0521822cv:C0457013
DiseaseAnoxic Encephalopathy

ITPR1 ITPR2

3.78e-0521822C0003132
DiseaseBrain Hypoxia

ITPR1 ITPR2

3.78e-0521822C1527348
DiseaseAnoxia of brain

ITPR1 ITPR2

3.78e-0521822C0995195
DiseaseWeyers acrofacial dysostosis

EVC2 EVC

3.78e-0521822C0457013
Diseaseautosomal dominant cerebellar ataxia (implicated_via_orthology)

ITPR1 ITPR2 ITPR3

4.87e-05121823DOID:1441 (implicated_via_orthology)
DiseaseMyocardial Preinfarction Syndrome

PAPPA PLAU

1.13e-0431822C0086666
DiseaseEllis-Van Creveld syndrome (is_implicated_in)

EVC2 EVC

1.13e-0431822DOID:12714 (is_implicated_in)
DiseaseAngina, Unstable

PAPPA PLAU

1.13e-0431822C0002965
DiseaseAnuria

AGT PLAU

1.13e-0431822C0003460
DiseaseColorectal Carcinoma

PCSK2 ACAP1 EVC2 KALRN TRPM7 ISLR SACS TLR2 TRAF3IP3 LGR6 CTNNB1 SNRNP200 CCDC93 SORL1

1.25e-0470218214C0009402
Diseasealcohol use disorder (implicated_via_orthology)

PCSK2 ANGPT2 ADRA1B BRD9 PRKACA PRKACB UNC13C

2.18e-041951827DOID:1574 (implicated_via_orthology)
DiseaseEllis-Van Creveld Syndrome

EVC2 EVC

2.25e-0441822C0013903
DiseaseAdrenal Cortical Adenoma

PRKACB CTNNB1

2.25e-0441822C0206667
Diseaseepilepsy (implicated_via_orthology)

KCNH7 KALRN SLC12A2 KIF4B UNC13C KCNH5

5.41e-041631826DOID:1826 (implicated_via_orthology)
DiseaseCiliopathies

EVC2 ZNF423 EVC CCDC39 NEK8

6.13e-041101825C4277690
DiseaseImmune System Diseases

TRPM7 EIF2AK4

7.79e-0471822C0021053
DiseaseNEPHRONOPHTHISIS 2

ZNF423 NEK8

1.03e-0381822C1865872
Diseasemitral valve prolapse (is_implicated_in)

AGT PLAU

1.32e-0391822DOID:988 (is_implicated_in)
Diseaseurinary bladder cancer (implicated_via_orthology)

PLAU CTNNB1

1.32e-0391822DOID:11054 (implicated_via_orthology)
DiseaseProstatic Neoplasms

PPFIBP2 TBC1D2 ITPR1 APPL2 SLC12A2 PRKACB INTS4 PLAU SPOP CTNNB1 TPBG

1.62e-0361618211C0033578
DiseaseMalignant neoplasm of prostate

PPFIBP2 TBC1D2 ITPR1 APPL2 SLC12A2 PRKACB INTS4 PLAU SPOP CTNNB1 TPBG

1.62e-0361618211C0376358
Diseasepost-traumatic stress disorder

DOCK4 TBC1D2 UNC13C OSBP2 LGR6 MGAT5B

1.64e-032021826EFO_0001358
Diseaseinterventricular septum thickness

ITPR2 IGF1R

1.65e-03101822EFO_0009287
DiseaseCardiomegaly

ITPR2 LIF ADRA1B AGT

1.68e-03821824C0018800
DiseaseCardiac Hypertrophy

ITPR2 LIF ADRA1B AGT

1.68e-03821824C1383860
DiseaseInternal Carotid Artery Diseases

AGT PLAU

2.01e-03111822C0750986
DiseaseArterial Diseases, Common Carotid

AGT PLAU

2.01e-03111822C0750987
DiseaseCarotid Atherosclerosis

AGT PLAU

2.01e-03111822C0577631
DiseaseAdrenal Gland Neoplasms

PRKACA CTNNB1

2.01e-03111822C0001624
DiseaseExternal Carotid Artery Diseases

AGT PLAU

2.01e-03111822C0600178
DiseaseCarotid Artery Diseases

AGT PLAU

2.01e-03111822C0007273
Diseaselevel of Sphingomyelin (d34:0) in blood serum

PELP1 SYNE2

2.01e-03111822OBA_2045176
DiseaseAdrenal Cancer

PRKACA CTNNB1

2.01e-03111822C0750887
Diseasecomplement factor H-related protein 5 measurement

ZBTB41 TLR2 SORL1

2.22e-03421823EFO_0008098
Diseaseobesity (implicated_via_orthology)

ITPR1 ITPR2 ITPR3 ZFHX4 CTNNB1 CORO7

2.24e-032151826DOID:9970 (implicated_via_orthology)
Diseasepulmonary fibrosis (implicated_via_orthology)

AGT PLAU

2.40e-03121822DOID:3770 (implicated_via_orthology)
Diseasedistal myopathy (implicated_via_orthology)

DYSF MYH15

2.40e-03121822DOID:11720 (implicated_via_orthology)
Diseasemyotonia congenita (implicated_via_orthology)

MSTO1 MYH15

2.40e-03121822DOID:2106 (implicated_via_orthology)
Diseasefocal segmental glomerulosclerosis (biomarker_via_orthology)

ANGPT2 AGT

2.40e-03121822DOID:1312 (biomarker_via_orthology)
Diseasetransient cerebral ischemia (biomarker_via_orthology)

CAB39 ITPR1 SLC12A2 AGT PLAU

2.96e-031571825DOID:224 (biomarker_via_orthology)
Diseasenephroblastoma (is_implicated_in)

IGF1R CTNNB1

3.28e-03141822DOID:2154 (is_implicated_in)
Diseasethyroid gland papillary carcinoma (is_marker_for)

PLAU CTNNB1

3.28e-03141822DOID:3969 (is_marker_for)
DiseaseKuhnt-Junius degeneration (is_marker_for)

IGF1R TLR2

3.28e-03141822DOID:10873 (is_marker_for)
Diseasered blood cell density measurement

PPP1R21 KALRN MYO9A DNAH2 ATP8B2 ADRA1B RORA KIF4B EIF2AK4 TRAF3IP3 KLHL8 ZRANB1 VPS13B

3.32e-0388018213EFO_0007978
Diseasemyocardial infarction (is_implicated_in)

PCSK2 AGT PAPPA PLAU

3.34e-03991824DOID:5844 (is_implicated_in)
Diseasetelomere length

BNC2 MCTP1 NINL CEP295 SPOP TNPO3 BBOF1

3.41e-033131827EFO_0004505
DiseaseFamilial Alzheimer Disease (FAD)

IDE IGF1R PLAU SORL1

3.47e-031001824C0276496
DiseaseAlzheimer's Disease

IDE IGF1R PLAU SORL1

3.59e-031011824C0002395
Diseaseacute graft vs. host disease, donor genotype effect measurement

KALRN RORA

3.77e-03151822EFO_0004599, EFO_0007892
Diseasehepatoblastoma (is_marker_for)

SPOP CTNNB1

3.77e-03151822DOID:687 (is_marker_for)
DiseaseLiver Cirrhosis

TRPM7 AGT PLAU CTNNB1

3.85e-031031824C0023890
DiseaseTPE interval measurement

RUFY1 LRIG3 IGF1R

4.09e-03521823EFO_0004644
DiseaseFibrosis, Liver

TRPM7 AGT PLAU CTNNB1

4.12e-031051824C0239946
DiseaseRolandic epilepsy

DPY19L2 KALRN

4.29e-03161822Orphanet_1945
Diseasediabetic retinopathy (implicated_via_orthology)

ANGPT2 AGT

4.29e-03161822DOID:8947 (implicated_via_orthology)
DiseaseHypotension

ADRA1B AGT PLAU

4.31e-03531823C0020649
Diseaselower face morphology measurement

ANAPC1 GCC2 RORA VPS13B

4.71e-031091824EFO_0010948
Diseaselevel of Sphingomyelin (d32:1) in blood serum

SYNE2 KCNH5

4.84e-03171822OBA_2045173
Diseaseperinatal necrotizing enterocolitis (biomarker_via_orthology)

TLR7 TLR2

4.84e-03171822DOID:8677 (biomarker_via_orthology)
Diseasevascular endothelial growth factor measurement

EVC2 DNAH2 RORA

5.03e-03561823EFO_0004762
DiseaseAlzheimer's disease (implicated_via_orthology)

IDE IGF1R PLAU

5.29e-03571823DOID:10652 (implicated_via_orthology)
DiseaseAlzheimer's disease (is_marker_for)

IDE ITPR1 IGF1R AGT PLAU CTNNB1

5.36e-032571826DOID:10652 (is_marker_for)
Diseasehepatocellular carcinoma (is_implicated_in)

CAB39 IGF1R TLR2 SPOP CTNNB1

5.41e-031811825DOID:684 (is_implicated_in)
Diseasesinusitis (is_marker_for)

TLR2 PLAU

5.42e-03181822DOID:0050127 (is_marker_for)
DiseaseAdrenocortical carcinoma

IGF1R CTNNB1

5.42e-03181822C0206686
DiseaseMalignant neoplasm of endometrium

SPOP CTNNB1

5.42e-03181822C0007103
DiseaseCarcinoma in situ of endometrium

SPOP CTNNB1

5.42e-03181822C0346191
DiseaseHemangiosarcoma

ANGPT2 CTNNB1

5.42e-03181822C0018923
Diseasedisease free survival

ICE1 CCDC168

5.42e-03181822EFO_0000409
DiseaseAlzheimer's disease (biomarker_via_orthology)

IDE IGF1R CTNNB1

5.55e-03581823DOID:10652 (biomarker_via_orthology)
Diseasekidney failure (biomarker_via_orthology)

PHEX TLR2

6.04e-03191822DOID:1074 (biomarker_via_orthology)
Diseasehydrocephalus (implicated_via_orthology)

MBOAT7 CCDC39

6.04e-03191822DOID:10908 (implicated_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
VEKHEHILLFLLNNS

TDRD1

1151

Q9BXT4
EALRDLLNNHILKSA

TGFBI

301

Q15582
TLRLFHTETLKHLQD

ARHGEF10

1131

O15013
HEKLSNLAQIAELSL

CFAP54

2991

Q96N23
LKNSIRSLDALHNIT

CDHR1

631

Q96JP9
LRSSHNELLNAEIKH

APBB2

41

Q92870
LQLKAHLDEARTLLH

RNF20

396

Q5VTR2
SLANLHQKSSEIEIL

EIF2AK4

1561

Q9P2K8
HLNLDETTKLLQDLH

BRD9

521

Q9H8M2
LTLLQKQHALDLDIT

BPIFB4

431

P59827
HSANINLHRKLLTKE

BNC2

881

Q6ZN30
SSHNQLLLLLHTDRS

CDCP2

346

Q5VXM1
LELQLLEHSLSTNKL

ANGPT2

156

O15123
LTLRIHSKNFHEDTL

ADRA1B

251

P35368
LLTRHKLLSAEFLEQ

CAB39

191

Q9Y376
KSLHDNLRSQTLIDL

GATB

196

O75879
SLNHKLDSHAELLDA

ACAP1

86

Q15027
AHDLHLSSLQLAKKA

APPBP2

406

Q92624
QLKNLSHLQTLNLSH

CD180

391

Q99467
FLLLLSLQEKEHASR

DIPK1B

206

Q5VUD6
SHTLLLHQKEINDLL

BBOF1

256

Q8ND07
KLENSLLDHRNKTIH

CA6

246

P23280
HSRLTEKLLEATHNN

FAM200A

221

Q8TCP9
LAANSLLNKLIHQSL

DDX25

61

Q9UHL0
LLNKLIHQSLVESSH

DDX25

66

Q9UHL0
LHQLQLAATLKEDSI

ADAT1

101

Q9BUB4
LHTELNLQKLSNDRI

AGT

396

P01019
LDRLHHSTQELLNTT

ATP8B2

586

P98198
TRSSLKHLNHQLQKL

CCDC39

426

Q9UFE4
LLSTAAQDLIHAELK

RAD21L1

346

Q9H4I0
IFNKDLLSTLHLLVA

PARVG

131

Q9HBI0
EKSHQVLAQLLDTLL

INTS4

121

Q96HW7
RLLHKSIQNSLLGHS

ISG20

136

Q96AZ6
AEDTITALLHNNRKL

ITPR2

591

Q14571
TALLHNNRKLLEKHI

ITPR2

596

Q14571
AEDTITALLHNNRKL

ITPR3

591

Q14573
TALLHNNRKLLEKHI

ITPR3

596

Q14573
LQKTLDRETQSAHHL

PCDHGB7

196

Q9Y5F8
KLETLSLNNNHLREL

LRRC57

86

Q8N9N7
LNGHLTKLATLNIHD

ANAPC1

1181

Q9H1A4
HLSELLKRTALHGES

ORC4

46

O43929
ITTLHNLLLHQEGAK

CTNNB1

256

P35222
TFEALKHLASLLLHN

DCAF1

371

Q9Y4B6
SLNALTHSSRLKLHL

KIF14

26

Q15058
RLHFHNLVKGLTDLS

NOP56

126

O00567
HFSSDLKDLLRNLLQ

PRKACA

261

P17612
RHSLHLTALVQLVKE

KRBA1

56

A5PL33
LSALSREQTHKLELQ

MCTP1

556

Q6DN14
QDAKHRLTLLSAQSL

MAN2A1

926

Q16706
AEDTITALLHNNRKL

ITPR1

591

Q14643
TALLHNNRKLLEKHI

ITPR1

596

Q14643
QKLSELDLTFNHLSR

LRIG3

311

Q6UXM1
LHSLVKLDLTDNQLT

LGR6

421

Q9HBX8
LTFNLRHESAKADLL

KCNH7

861

Q9NS40
LKNLHLNSHVKETTR

MTO1

296

Q9Y2Z2
LSLHSKLNATADILR

LIF

131

P15018
TNDLSFIHLTKHREL

JCAD

661

Q9P266
AVLKALNATLHSNLL

KCNE3

16

Q9Y6H6
SLSKLLEELSHQLLQ

IKBKE

641

Q14164
HKHSRLAEVLQLGSD

KCNH5

176

Q8NCM2
LSHLQQDSLKLRDSL

DDX56

146

Q9NY93
NLNLREIDHTKSLTD

FSIP2

1316

Q5CZC0
QKTLEHLQLSHDQLL

HK2

471

P52789
SADDLIHLQRAKAIL

CCNYL2

346

Q5T2Q4
LHRDSHITNLKGLNL

CORO7

481

P57737
RHSHALVSLSFLKNL

IGF1R

391

P08069
SLSHLKSLDLSHNLI

ISLR

96

O14498
QHLENSLSAETRIKL

MACO1

566

Q8N5G2
DQILRHSLLLHSKVS

MGAT5B

136

Q3V5L5
DKLLGELHTLRDQHL

PCM1

411

Q15154
QHLHKLLSSSDLNIE

KLHL8

211

Q9P2G9
LHQTLEALARDLTKL

MSTO1

516

Q9BUK6
HSAESQILKHLLKNL

NNMT

31

P40261
ITSLLDKLHSTRQHL

KALRN

281

O60229
THLILHRDLKTQNIL

NEK8

121

Q86SG6
SSALIKAQELHALTH

HERVK_113

586

P63132
TLHGLEQEHLRKSLA

EVC2

501

Q86UK5
KLVSLASEVQDLHLA

MBOAT7

111

Q96N66
LSTDDLNSLIAHAHR

IMMT

396

Q16891
LKQELAIHDSLTNRT

KIF9

366

Q9HAQ2
DNARLAHLILSLEAK

OTUD7A

416

Q8TE49
AHLILSLEAKLNLLH

OTUD7A

421

Q8TE49
QLLDTKDQSHDLGLH

PAPPA

1121

Q13219
QLQLKTLHEDLSGRL

PPP1R21

201

Q6ZMI0
LRKQLLEHSELAFHT

DPY19L2

526

Q6NUT2
EQELHSLLASLHTLL

PELP1

261

Q8IZL8
ELHHTLKNLSLKLDD

OSBP2

301

Q969R2
SSALIKAQELHALTH

ERVK-7

586

P63135
SSALIKAQELHALTH

ERVK-6

586

Q9BXR3
VNDLLFLKVTSQLHH

PPFIBP2

666

Q8ND30
DLRNLKLKLHTFESH

RBBP7

301

Q16576
SLLAHLLQSKSELSH

PAQR8

126

Q8TEZ7
LLLKTHQLSLDAFLV

PCID2

331

Q5JVF3
LLATNRDKEFHSHLT

CEP135

1036

Q66GS9
KHLEELRASHTSLQA

CCDC93

331

Q567U6
LNTLVQKLHDFLAHS

ATRX

11

P46100
LSLTERSQIAHALKL

GBX1

286

Q14549
SEHKLQTKTLNTLHL

ICE1

671

Q9Y2F5
HFSSDLKDLLRNLLQ

PRKACB

261

P22694
SLVHIINLLQDSKFH

DOCK4

641

Q8N1I0
ELHSTATQLAADLLK

CTNNAL1

396

Q9UBT7
DLHLSDVFLKALNHL

C6

331

P13671
DLRLSLHLQDQDSVK

DHX57

776

Q6P158
LSALSDLHAHKLRVD

HBA1;

81

P69905
LSLQEEKTRVSQHHL

CCDC13

401

Q8IYE1
AHRLKNQSSLLHKTL

CHD1L

176

Q86WJ1
DLSHQERLQSKSLHL

DSN1

66

Q9H410
TLQSEHDTLLERHNK

GCC2

1381

Q8IWJ2
IHSNVHSDRLLELKS

CEP350

2446

Q5VT06
NSALDHALRTATILK

AKNAD1

796

Q5T1N1
ILHRDLKTSNLLLSH

CDK11A

546

Q9UQ88
LNLLHTELAKQLADT

APPL2

96

Q8NEU8
LLSRHLKQLLSDHEL

DENND5A

896

Q6IQ26
HSSALERLETKLHLL

LURAP1L

86

Q8IV03
DTTTRHLLAAKVLNL

ITIH6

581

Q6UXX5
QAKLSEHRHKLLQEL

KIF4B

591

Q2VIQ3
SRALLHSDEHQLLTN

KCNMB4

96

Q86W47
LHNRKVEHEALGSSL

KANSL2

226

Q9H9L4
SLQKALHHLSRLRDL

LAS2

346

Q8IYD9
SRLHIEALLHGNITK

IDE

721

P14735
ISLKNNLDHLLASLL

HEATR1

386

Q9H583
LHLKDLLHLDTALRQ

EVC

216

P57679
LTSHLESKALEIQLN

CCDC168

6416

Q8NDH2
ADTFLNLTLKHLHLL

B3GNT6

191

Q6ZMB0
HHVISQLQDKRLSLS

CEP295

926

Q9C0D2
LLDDVQLVNTLHTSK

DNAH2

3566

Q9P225
LESLLIIHDANSRLK

SACS

3521

Q9NZJ4
SLTLQQLKALLNHLD

SLC39A14

56

Q15043
EKRVIQLHLQHSSLL

CFAP47

1621

Q6ZTR5
HHLSQITEAALALKL

DYSF

746

O75923
SVLKDLFLEHAHNLA

CEBPG

116

P53567
HLKGIDLQTIHSREL

MCOLN2

226

Q8IZK6
NRIATKASHLLETLL

CEBPZ

396

Q03701
QHLAELLLAHTDLKS

LRRC74B

181

Q6ZQY2
LLTLHQHLDLSSSEK

PACSIN3

246

Q9UKS6
GKLQELHRLLQSLES

OSBPL7

206

Q9BZF2
THIHKEELELRNQSL

PPEF1

71

O14829
DTLLSNAKHLEILFT

IPO8

706

O15397
LTLSHLAAVAHKTLQ

RARS2

526

Q5T160
DTLPLSKNADHLLHL

UTP4

371

Q969X6
LSHEQKLSQSLEIAL

UBOX5

421

O94941
AADLLLHSKASNLLL

SORL1

206

Q92673
ISHLSSLIAQLEEKQ

TRIM27

226

P14373
SADTLAHHNDIALLK

PLAU

266

P00749
DNLALIHAARDTLKL

UVSSA

321

Q2YD98
IKHLHESLLQQLQDS

SYNE2

2226

Q8WXH0
LLVDLKATVLNLHQH

SYNE2

4056

Q8WXH0
LSLNKKIDHELHRLQ

SYNE2

4926

Q8WXH0
VHIHQESALAKLLLT

TMEM176A

21

Q96HP8
PTHLDLSALHNVLNK

NHS

1086

Q6T4R5
ALDRQTATQLLKLAH

RPL7A

86

P62424
LTHLNEASVLHTLKR

MYH15

111

Q9Y2K3
LQRELQHEKDTSSLL

RUFY1

561

Q96T51
DLNALHKTTKSQRHL

SEMG1

86

P04279
SQIDRDLHKLSLLAQ

SETX

956

Q7Z333
LKTDSLQRLHATHNL

SHPRH

1061

Q149N8
QKSILRDALSDLALH

CCT4

301

P50991
FDLSVLKLHHSLQQS

SERTAD1

46

Q9UHV2
FHRLSEENTLLKNDL

NINL

1086

Q9Y2I6
ESTQALLEHLKAHSR

PLAGL2

166

Q9UPG8
VRHLLTDLQDHLAKD

RINL

306

Q6ZS11
FLSAHKSEQLLRLHK

RNF213

5081

Q63HN8
HRELESQLHVLQSKL

TRAF3IP3

336

Q9Y228
EALSQHLQSSLHKEK

ZFHX4

3411

Q86UP3
KLLDQLHNSLRIDLS

UNC13C

1481

Q8NB66
QHLDLLVRDSSHPNK

RNF112

311

Q9ULX5
NLEKHQSHLQAKSLL

MRPS9

171

P82933
LELNSSLEFKLHRLH

RMND5B

186

Q96G75
AELEHLAQNISKSHL

RORA

271

P35398
HLLNTKLEHVNRDLS

SMC1B

236

Q8NDV3
LILADLHSADQLKTQ

SPOP

306

O43791
SLENHLAKTHRSLLL

ZBTB41

221

Q5SVQ8
RLNELLKEHSSTANI

SLC12A2

1151

P55011
SSALIKAQELHALTH

ERVK-10

586

P10266
IRSHLQDLKDITHNI

SEPTIN12

291

Q8IYM1
SSALIKAQELHALTH

ERVK-8

586

P63133
LHQLTKLRFLQTEDS

RPP25L

81

Q8N5L8
SSALIKAQELHALTH

ERVK-11

586

Q9UQG0
NEHILKLDQATLSLA

PHEX

216

P78562
SLLTLLNRHKNIHTG

ZNF780A

231

O75290
ELKVLRLHSNSLQHV

TLR7

291

Q9NYK1
SLHLFLQSHLNSEDI

SNX10

116

Q9Y5X0
LHVVKLLASALSAND

PPP6R1

356

Q9UPN7
DSHASLRDSLLTHIQ

TNPO3

81

Q9Y5L0
LRDSLLTHIQNLKDL

TNPO3

86

Q9Y5L0
DPHVKTNLLLQAHLS

SNRNP200

1886

O75643
IHHLLLSLQKLREDF

ZBED6

716

P86452
DLTHHKASAELLRLT

VPS13B

3401

Q7Z7G8
IAHLRKVISEHLTNL

ZBED9

1171

Q6R2W3
ESLHLEDNALKVLHN

TPBG

261

Q13641
SFQTHLKLHLELLLR

ZNF423

646

Q2M1K9
TLILRQNHLASLEKT

TLR2

391

O60603
RELSISKHLAQNLID

TRPM7

1266

Q96QT4
DKDLSRNSLLHIHQR

ZNF214

336

Q9UL59
DSERKLLHVHFLSAQ

ZRANB1

621

Q9UGI0
HSLRLLLEEQLSNKD

VWA3A

531

A6NCI4
KIQALESRSHHLLGL

TBC1D2

581

Q9BYX2
LSKDEQLLHLSSQLE

GOLGB1

2811

Q14789
HAVFSLLSLQELDLK

LRRC8C

606

Q8TDW0
ENLHELDLSNSKLHA

NLRP13

726

Q86W25
SLTHLNLSKNSLRDE

NLRP13

896

Q86W25
HALLNSKDLEHNTKT

MYO9A

516

B2RTY4
HSLSHKEQLLQEFRE

PDE4DIP

441

Q5VU43
HLTVLTSKRNQLHDE

PCSK2

411

P16519