Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionisoleucine-tRNA ligase activity

IARS2 IARS1

8.58e-062592GO:0004822
GeneOntologyMolecularFunctionphosphatidylinositol-5-phosphate binding

WASHC2C SH3PXD2A WASHC2A

4.16e-0523593GO:0010314
GeneOntologyMolecularFunctionmetallocarboxypeptidase activity

CPA6 CPO CPB1

1.04e-0431593GO:0004181
GeneOntologyMolecularFunctionphosphatidylinositol-3,4-bisphosphate binding

WASHC2C SH3PXD2A WASHC2A

1.50e-0435593GO:0043325
GeneOntologyMolecularFunctionphosphatidylinositol-4-phosphate binding

WASHC2C SH3PXD2A WASHC2A

1.63e-0436593GO:0070273
GeneOntologyMolecularFunctionmetallopeptidase activity

MMP25 CPA6 BMP1 CPO CPB1

3.10e-04200595GO:0008237
GeneOntologyMolecularFunctionretromer complex binding

WASHC2C WASHC2A

3.80e-0410592GO:1905394
GeneOntologyMolecularFunctionphosphatidylinositol-3-phosphate binding

WASHC2C SH3PXD2A WASHC2A

3.86e-0448593GO:0032266
GeneOntologyMolecularFunctionphosphatidylinositol-3,4,5-trisphosphate binding

WASHC2C PIRT WASHC2A

4.10e-0449593GO:0005547
GeneOntologyMolecularFunctioncarboxypeptidase activity

CPA6 CPO CPB1

4.10e-0449593GO:0004180
GeneOntologyMolecularFunctionphosphatidylinositol bisphosphate binding

WASHC2C PIRT SH3PXD2A WASHC2A

4.51e-04121594GO:1902936
GeneOntologyMolecularFunctionbenzodiazepine receptor activity

GABRE GABRG2

4.64e-0411592GO:0008503
GeneOntologyMolecularFunctionaminoacyl-tRNA editing activity

IARS2 IARS1

7.63e-0414592GO:0002161
GeneOntologyMolecularFunctionmetalloexopeptidase activity

CPA6 CPO CPB1

1.17e-0370593GO:0008235
GeneOntologyMolecularFunctionGABA-gated chloride ion channel activity

GABRE GABRG2

1.27e-0318592GO:0022851
GeneOntologyMolecularFunctionGABA-A receptor activity

GABRE GABRG2

1.42e-0319592GO:0004890
GeneOntologyMolecularFunctionneurotransmitter transmembrane transporter activity

SLC6A16 SLC28A2

1.74e-0321592GO:0005326
GeneOntologyMolecularFunctionGABA receptor activity

GABRE GABRG2

1.91e-0322592GO:0016917
GeneOntologyMolecularFunctionlipid binding

STARD13 WASHC2C PIRT SH3PXD2A FZD5 OSBPL7 OSBP2 EPDR1 WASHC2A

2.32e-03988599GO:0008289
GeneOntologyMolecularFunctionphosphatidylinositol-4,5-bisphosphate binding

WASHC2C SH3PXD2A WASHC2A

2.80e-0395593GO:0005546
GeneOntologyMolecularFunctionphosphatidylinositol phosphate binding

WASHC2C PIRT SH3PXD2A WASHC2A

2.84e-03199594GO:1901981
GeneOntologyMolecularFunctionenzyme activator activity

STARD13 MMP25 ARHGAP15 SH3PXD2A APAF1 ARHGAP20 NSMAF

3.10e-03656597GO:0008047
GeneOntologyMolecularFunctionphosphatidylinositol-3,5-bisphosphate binding

WASHC2C WASHC2A

3.78e-0331592GO:0080025
GeneOntologyBiologicalProcessisoleucyl-tRNA aminoacylation

IARS2 IARS1

7.50e-062572GO:0006428
HumanPhenoPulmonary arterial medial hypertrophy

LIFR BMPR2

1.46e-052202HP:0004964
DomainIle-tRNA-ligase

IARS2 IARS1

9.48e-062582IPR002301
DomainFAM21

WASHC2C WASHC2A

9.48e-062582IPR027308
DomainZn_pept

CPA6 CPO CPB1

2.24e-0518583SM00631
DomainCARBOXYPEPT_ZN_2

CPA6 CPO CPB1

2.66e-0519583PS00133
DomainFAM21/CAPZIP

WASHC2C WASHC2A

2.84e-053582IPR029341
DomainCAP-ZIP_m

WASHC2C WASHC2A

2.84e-053582PF15255
DomainCARBOXYPEPT_ZN_1

CPA6 CPO CPB1

3.12e-0520583PS00132
DomainPeptidase_M14

CPA6 CPO CPB1

4.82e-0523583PF00246
DomainPeptidase_M14

CPA6 CPO CPB1

4.82e-0523583IPR000834
DomainPH_dom-like

BMX ARHGAP15 NBEAL1 OSBPL7 OSBP2 ARHGAP20 PLEKHB1 NSMAF

4.84e-05426588IPR011993
DomainVal/Leu/Ile-tRNA-synth_edit

IARS2 IARS1

1.41e-046582IPR009008
DomainAnticodon_1

IARS2 IARS1

1.41e-046582PF08264
DomainM/V/L/I-tRNA-synth_anticd-bd

IARS2 IARS1

1.41e-046582IPR013155
Domain-

IARS2 IARS1

1.41e-0465823.90.740.10
Domainaa-tRNA-synth_Ia

IARS2 IARS1

1.97e-047582IPR002300
DomaintRNA-synt_1

IARS2 IARS1

1.97e-047582PF00133
DomainPH

BMX ARHGAP15 OSBPL7 OSBP2 ARHGAP20 PLEKHB1

2.18e-04278586SM00233
DomainPH_DOMAIN

BMX ARHGAP15 OSBPL7 OSBP2 ARHGAP20 PLEKHB1

2.22e-04279586PS50003
DomainPH_domain

BMX ARHGAP15 OSBPL7 OSBP2 ARHGAP20 PLEKHB1

2.26e-04280586IPR001849
DomainPH-BEACH_dom

NBEAL1 NSMAF

2.62e-048582IPR023362
Domain-

CPA6 CPB1

2.62e-0485823.30.70.340
Domain-

NBEAL1 NSMAF

2.62e-0485822.30.29.40
DomainPropep_M14

CPA6 CPB1

2.62e-048582PF02244
DomainPH_BEACH

NBEAL1 NSMAF

2.62e-048582PS51783
DomainM14A_act_pep

CPA6 CPB1

2.62e-048582IPR003146
DomainWD40_repeat_dom

DCAF8L1 NBEAL1 TAF1C APAF1 DNAI2 NSMAF

3.11e-04297586IPR017986
DomainBEACH_dom

NBEAL1 NSMAF

3.36e-049582IPR000409
DomainBEACH

NBEAL1 NSMAF

3.36e-049582PS50197
DomainBeach

NBEAL1 NSMAF

3.36e-049582PF02138
Domain-

NBEAL1 NSMAF

3.36e-0495821.10.1540.10
DomainBeach

NBEAL1 NSMAF

3.36e-049582SM01026
Domain-

IARS2 IARS1

5.12e-04115821.10.730.10
Domain-

DCAF8L1 NBEAL1 TAF1C APAF1 DNAI2 NSMAF

5.70e-043335862.130.10.10
DomainWD40/YVTN_repeat-like_dom

DCAF8L1 NBEAL1 TAF1C APAF1 DNAI2 NSMAF

5.88e-04335586IPR015943
DomainOxysterol-bd

OSBPL7 OSBP2

6.13e-0412582IPR000648
DomainOxysterol-bd_CS

OSBPL7 OSBP2

6.13e-0412582IPR018494
DomainOxysterol_BP

OSBPL7 OSBP2

6.13e-0412582PF01237
DomainOSBP

OSBPL7 OSBP2

6.13e-0412582PS01013
DomainPH

BMX ARHGAP15 OSBPL7 OSBP2 PLEKHB1

7.16e-04229585PF00169
DomainRhoGAP

STARD13 ARHGAP15 ARHGAP20

9.44e-0462583SM00324
DomaintRNAsynth_Ia_anticodon-bd

IARS2 IARS1

9.70e-0415582IPR009080
DomainRhoGAP

STARD13 ARHGAP15 ARHGAP20

9.89e-0463583PF00620
DomainRHOGAP

STARD13 ARHGAP15 ARHGAP20

1.04e-0364583PS50238
DomainRhoGAP_dom

STARD13 ARHGAP15 ARHGAP20

1.04e-0364583IPR000198
Domain-

STARD13 ARHGAP15 ARHGAP20

1.04e-03645831.10.555.10
DomainWD40

DCAF8L1 NBEAL1 APAF1 DNAI2 NSMAF

1.24e-03259585PF00400
DomainPropept_inh

CPA6 CPB1

1.25e-0317582IPR009020
Domain-

BMX ARHGAP15 OSBPL7 OSBP2 ARHGAP20 PLEKHB1

1.31e-033915862.30.29.30
Domainaa-tRNA-synth_I_CS

IARS2 IARS1

1.40e-0318582IPR001412
DomainWD40

DCAF8L1 NBEAL1 APAF1 DNAI2 NSMAF

1.44e-03268585SM00320
DomainWD40_repeat

DCAF8L1 NBEAL1 APAF1 DNAI2 NSMAF

1.54e-03272585IPR001680
DomainAA_TRNA_LIGASE_I

IARS2 IARS1

1.57e-0319582PS00178
DomainWD_REPEATS_1

DCAF8L1 NBEAL1 APAF1 DNAI2 NSMAF

1.70e-03278585PS00678
DomainWD_REPEATS_2

DCAF8L1 NBEAL1 APAF1 DNAI2 NSMAF

1.72e-03279585PS50082
DomainWD_REPEATS_REGION

DCAF8L1 NBEAL1 APAF1 DNAI2 NSMAF

1.72e-03279585PS50294
DomainGABAA/Glycine_rcpt

GABRE GABRG2

2.30e-0323582IPR006028
DomainRho_GTPase_activation_prot

STARD13 ARHGAP15 ARHGAP20

2.59e-0388583IPR008936
DomainZnMc

MMP25 BMP1

3.65e-0329582SM00235
DomainPeptidase_Metallo

MMP25 BMP1

3.65e-0329582IPR006026
Pubmed

Control of HIV replication in astrocytes by a family of highly conserved host proteins with a common Rev-interacting domain (Risp).

WASHC2C WASHC2A

2.83e-06259220827171
Pubmed

Isoleucylation properties of native human mitochondrial tRNAIle and tRNAIle transcripts. Implications for cardiomyopathy-related point mutations (4269, 4317) in the tRNAIle gene.

IARS2 IARS1

2.83e-0625929466989
Pubmed

FAM21 is critical for TLR2/CLEC4E-mediated dendritic cell function against Candida albicans.

WASHC2C WASHC2A

2.83e-06259236717248
Pubmed

Somatic frameshift mutations of bone morphogenic protein receptor 2 gene in gastric and colorectal cancers with microsatellite instability.

BMP1 BMPR2

2.83e-06259220955454
Pubmed

Identification of a novel Rev-interacting cellular protein.

WASHC2C WASHC2A

2.83e-06259215847701
Pubmed

Expression of oxysterol binding protein isoforms in opisthorchiasis-associated cholangiocarcinoma: a potential molecular marker for tumor metastasis.

OSBPL7 OSBP2

2.83e-06259221763455
Pubmed

Identification and characterization of three members of the human metallocarboxypeptidase gene family.

CPA6 CPO

8.48e-06359211836249
Pubmed

MicroRNA-125b promotes invasion and metastasis of gastric cancer by targeting STARD13 and NEU1.

STARD13 NEU1

8.48e-06359227220320
Pubmed

Placentation defects are highly prevalent in embryonic lethal mouse mutants.

WASHC2C SH3PXD2A CAPZA2 WASHC2A

2.91e-0510359429539633
Pubmed

FGF8 and BMP2 mediated dynamic regulation of dental mesenchyme proliferation and differentiation via Lhx8/Suv39h1 complex.

BMP1 BMPR2 COL11A1

4.06e-053959333580754
Pubmed

The mammalian oxysterol-binding protein-related proteins (ORPs) bind 25-hydroxycholesterol in an evolutionarily conserved pocket.

OSBPL7 OSBP2

7.87e-05859217428193
Pubmed

A FAM21-containing WASH complex regulates retromer-dependent sorting.

WASHC2C WASHC2A

7.87e-05859219922874
Pubmed

Loss of postsynaptic GABA(A) receptor clustering in gephyrin-deficient mice.

GABRG2 DLG4

1.01e-04959210531433
Pubmed

Arid1b haploinsufficiency disrupts cortical interneuron development and mouse behavior.

GABRG2 DLG4 CREBBP

1.21e-045659329184203
Pubmed

The OSBP-related protein family in humans.

OSBPL7 OSBP2

1.54e-041159211483621
Pubmed

Genome-wide association study of body mass index in 23 000 individuals with and without asthma.

STARD13 ADCY3

1.54e-041159223517042
Pubmed

Enlarged dendritic spines and pronounced neophobia in mice lacking the PSD protein RICH2.

DLG4 CNTN1

1.85e-041259226969129
Pubmed

Apaf1-deficient cortical neurons exhibit defects in axonal outgrowth.

APAF1 DLG4

1.85e-041259225975226
Pubmed

A family of 12 human genes containing oxysterol-binding domains.

OSBPL7 OSBP2

1.85e-041259211735225
Pubmed

The Arp2/3 activator WASH controls the fission of endosomes through a large multiprotein complex.

WASHC2C WASHC2A

1.85e-041259219922875
Pubmed

An oxysterol-binding protein family identified in the mouse.

OSBPL7 OSBP2

1.85e-041259212215260
Pubmed

Loss of strumpellin in the melanocytic lineage impairs the WASH Complex but does not affect coat colour.

WASHC2C WASHC2A

1.85e-041259227390154
Pubmed

Protein phosphatase 1α interacting proteins in the human brain.

PPP1R3E PPP1R18 CNTN1

2.06e-046759322321011
Pubmed

Reduced cortical BDNF expression and aberrant memory in Carf knock-out mice.

GABRG2 DLG4

2.54e-041459220519520
Pubmed

Expression of the Neuronal tRNA n-Tr20 Regulates Synaptic Transmission and Seizure Susceptibility.

GABRG2 DLG4

2.93e-041559232853550
Pubmed

Protein array analysis of oligomerization-induced changes in alpha-synuclein protein-protein interactions points to an interference with Cdc42 effector proteins.

ARHGAP15 IARS1

2.93e-041559218541383
Pubmed

Retriever is a multiprotein complex for retromer-independent endosomal cargo recycling.

WASHC2C WASHC2A

2.93e-041559228892079
Pubmed

Impaired OTUD7A-dependent Ankyrin regulation mediates neuronal dysfunction in mouse and human models of the 15q13.3 microdeletion syndrome.

GABRG2 DLG4 LSM11 KCNB2

3.56e-0419759436604605
Pubmed

Strong genetic evidence for a selective influence of GABAA receptors on a component of the bipolar disorder phenotype.

GABRE GABRG2

4.25e-041859219078961
Pubmed

IgSF21 promotes differentiation of inhibitory synapses via binding to neurexin2α.

GABRG2 DLG4

4.25e-041859228864826
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

WASHC2C ARHGAP15 CAPZA2 NCSTN EPDR1 WASHC2A ADCY3 GPATCH2L

4.70e-04108459811544199
Pubmed

COMMD1 is linked to the WASH complex and regulates endosomal trafficking of the copper transporter ATP7A.

WASHC2C WASHC2A

4.75e-041959225355947
Pubmed

Genome-wide CRISPR Screen to Identify Genes that Suppress Transformation in the Presence of Endogenous KrasG12D.

WASHC2C WASHC2A

7.00e-042359231748650
Pubmed

Conditional Deletion of CC2D1A Reduces Hippocampal Synaptic Plasticity and Impairs Cognitive Function through Rac1 Hyperactivation.

ARHGAP15 DLG4

7.00e-042359230992372
Pubmed

The Maternal Microbiome Programs the m6A Epitranscriptome of the Mouse Fetal Brain and Intestine.

GABRG2 FZD5

8.28e-042559235874829
Pubmed

Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.

BMP1 LIFR COL11A1 EPDR1

8.44e-0424859424006456
Pubmed

Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.

STARD13 ARHGAP15 SH3PXD2A CAPZA2 LSM11 ARHGAP20 AKAP8L

8.91e-0491659732203420
Pubmed

Genetic loci influencing natural variations in femoral bone morphometry in mice.

BMP1 COL11A1

9.66e-042759211518254
Pubmed

Pre-synaptic localization of the γ-secretase-inhibiting protein p24α2 in the mammalian brain.

DLG4 NCSTN

9.66e-042759225438880
Pubmed

Neuronal expression of ILEI/FAM3C and its reduction in Alzheimer's disease.

DLG4 NCSTN

9.66e-042759227256505
Pubmed

BMP-binding protein twisted gastrulation is required in mammary gland epithelium for normal ductal elongation and myoepithelial compartmentalization.

BMP1 BMPR2

1.04e-032859223103586
Pubmed

Autism candidate gene DIP2A regulates spine morphogenesis via acetylation of cortactin.

DLG4 CREBBP

1.04e-032859231600191
Pubmed

The splicing regulator PTBP2 controls a program of embryonic splicing required for neuronal maturation.

GABRG2 DLG4

1.04e-032859224448406
Pubmed

Mouse screen reveals multiple new genes underlying mouse and human hearing loss.

STARD13 WASHC2C SH3PXD2A CAPZA2 DLG4 LSM11 WASHC2A SLC66A3

1.14e-03124259830973865
Pubmed

Mitochondrial Raf1 Regulates Glutamine Catabolism.

IARS2 PSMG2 AKAP8L SLC66A3

1.47e-0328859438496616
Pubmed

RUNX1 and TGF-β signaling cross talk regulates Ca2+ ion channels expression and activity during megakaryocyte development.

BMP1 BMPR2

1.62e-033559232281291
Cytoband8q13.2

CPA6 KCNB2

8.86e-05115928q13.2
CytobandEnsembl 112 genes in cytogenetic band chr2q33

BMPR2 NBEAL1 FZD5 CPO

1.45e-04205594chr2q33
Cytoband2q33.3

FZD5 CPO

6.90e-04305922q33.3
GeneFamilyCarboxypeptidases

CPA6 CPO CPB1

1.40e-05214131321
GeneFamilyWASH complex

WASHC2C WASHC2A

7.48e-0564121331
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

BMX ARHGAP15 OSBPL7 OSBP2 PLEKHB1

9.82e-05206415682
GeneFamilyWD repeat domain containing|BEACH domain containing

NBEAL1 NSMAF

1.79e-0494121230
GeneFamilyRho GTPase activating proteins|BCH domain containing

STARD13 ARHGAP15 ARHGAP20

1.97e-0450413721
GeneFamilyWD repeat domain containing

DCAF8L1 NBEAL1 APAF1 DNAI2 NSMAF

3.01e-04262415362
GeneFamilyOxysterol binding proteins|Pleckstrin homology domain containing

OSBPL7 OSBP2

3.26e-0412412670
GeneFamilyAminoacyl tRNA synthetases, Class I

IARS2 IARS1

8.37e-0419412131
GeneFamilyGamma-aminobutyric acid type A receptor subunits

GABRE GABRG2

8.37e-0419412563
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

GABRE CPB1 KCNB2 ARHGAP20 SLC7A10

2.36e-06161595a006491c991e6a134be20ad75092a91f3b7c3c91
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

GABRE CPB1 KCNB2 ARHGAP20 SLC7A10

2.36e-061615954f25eeabb841b0b9204cdd4e71d5e131e7868184
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Macroglial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL11A1 PIRT EPDR1 PLEKHB1 CNTN1

4.19e-061815951037051eb82313c13346617b33f3c4c648181c4d
ToppCelldroplet-Lung-21m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l30|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GABRE COL11A1 EPDR1 PLEKHB1 CNTN1

4.91e-061875956f7f293c9cf35261e0e3614e46ec1fb00a701b63
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GABRG2 KIAA1549L DLG4 KCNB2 ARHGAP20

6.01e-06195595ffbab350e67d9c4b66c0ab84550daec8b8139a27
ToppCellCOPD-Endothelial-VE_Capillary_B|Endothelial / Disease state, Lineage and Cell class

STARD13 LIFR BMPR2 WASHC2C WASHC2A

6.32e-0619759530dbc05ea66892d2e18ff375ffa86d1db7bc4083
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c11-GNLY|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TAF1C OSBP2 FAM131A WASHC2A

3.89e-051435948f897278f9ccc82ae35e4f30c5f930b2a3eb509d
ToppCell356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1.5|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

BMP1 LSM11 EPDR1 CREBBP

6.02e-051605948bb873704895c3b35bba8af78fedbabf7df42e71
ToppCell3'-Distal_airway-Epithelial-Airway_epithelium-brush_cell_of_trachebronchial_tree-Tuft|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

BMX KIAA1549L CPB1 KCNB2

6.32e-051625940ccdb224ee3c585a6d0caffde5608d9d3cc452f8
ToppCell3'-Distal_airway-Epithelial-Airway_epithelium-brush_cell_of_trachebronchial_tree-Tuft-Tuft_L.0.7.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

BMX KIAA1549L CPB1 KCNB2

6.32e-051625949ccee8e7e78e16b0149a94867e12d86d3b04f9b9
ToppCell3'-Distal_airway-Epithelial-Airway_epithelium-brush_cell_of_trachebronchial_tree|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

BMX KIAA1549L CPB1 KCNB2

6.32e-051625940d35752a7249b3c62b8007ec8a775c37d16b8d31
ToppCellCV-Mild-7|Mild / Virus stimulation, Condition and Cluster

BMP1 IARS1 EPDR1 NSMAF

8.15e-05173594c9bbca9313a0fdf146c8c995624b94b937e818d8
ToppCell3'-GW_trimst-1-LargeIntestine-Epithelial-progenitor-Germ|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MMP25 DCAF8L1 CACNA1I SLC66A3

8.71e-05176594eea554ea75580f8dd5fefb57e7f33441ab86b884
ToppCell3'-GW_trimst-1-LargeIntestine-Epithelial-progenitor|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MMP25 DCAF8L1 CACNA1I SLC66A3

8.71e-05176594d5cee483d2a60f82fdc67ad447b589d022fe8c97
ToppCellP15-Epithelial-epithelial_progenitor_cell-epithelial_unknown_3|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

STARD13 COL11A1 EPDR1 PLEKHB1

8.71e-05176594792f414f5092aba14260b8e16378e793a822498e
ToppCellfacs-Marrow-Granulocytes-3m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STARD13 TDRD9 PLEKHB1 SLC7A10

9.10e-051785946d9ecfaeb50d562899380de379ebf7b99fd8adc9
ToppCellfacs-Marrow-Granulocytes-3m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STARD13 TDRD9 PLEKHB1 SLC7A10

9.10e-05178594d3f518cd75b02e85d45cbb9b2eff30f0272512a8
ToppCellURO-Lymphocyte-T_NK-CD4_TCM|URO / Disease, Lineage and Cell Type

ARHGAP15 NBEAL1 CACNA1I PLEKHB1

9.29e-05179594cdf972acf23c7a22c99a336ee0f9cc51e0fa6f67
ToppCell3'-Adult-Appendix-Endothelial-blood_vessel_EC-Mature_arterial_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LIFR BMPR2 CAPZA2 AHNAK2

1.06e-04185594fa94c4a1660967f211ba095606cd0aa37d38e17a
ToppCell343B-Fibroblasts-Fibroblast-E|343B / Donor, Lineage, Cell class and subclass (all cells)

FAM131A ARHGAP20 ADCY3 AHNAK2

1.08e-0418659459db239f1864a5d4f1570c93219dbd7ac5b6db35
ToppCelldroplet-Lung-LUNG-30m-Mesenchymal-Alveolar_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STARD13 EPDR1 SLC7A10 CNTN1

1.08e-04186594ca5e9c6531cb5d199e27509bfab1d62e3937177e
ToppCelldroplet-Lung-LUNG-30m-Mesenchymal-fibroblast_of_lung|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STARD13 EPDR1 SLC7A10 CNTN1

1.08e-041865941ed71b229f40a680071b14f5a7a19706e0fd14b1
ToppCell343B-Fibroblasts-Fibroblast-E-|343B / Donor, Lineage, Cell class and subclass (all cells)

FAM131A ARHGAP20 ADCY3 AHNAK2

1.08e-041865941bac7825c2fe3e6cdff65026b09b9ccaa40fa27f
ToppCell3'-Adult-Appendix-Endothelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LIFR BMPR2 CAPZA2 AHNAK2

1.10e-04187594ec98d5e480b08854dfd0ba6b1dc6610455f90640
ToppCell3'-Adult-Appendix-Endothelial-blood_vessel_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LIFR BMPR2 CAPZA2 AHNAK2

1.10e-0418759437d8ee5c8bd6324749e5a2adef1d0482c75da80c
ToppCell10x3'2.3-week_12-13-Mesenchymal_osteo-stroma-osteochondral_precursor|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

BMP1 LIFR COL11A1 KIAA1549L

1.12e-04188594ed92cddf47defea2f904d36c7ae05ffa323349a9
ToppCellCOPD-Endothelial-VE_Arterial|Endothelial / Disease state, Lineage and Cell class

LIFR BMPR2 BMX ARHGAP20

1.19e-04191594ef16ad1c1cd2c0c0377957398c98775b62a81754
ToppCell10x3'2.3-week_12-13-Mesenchymal_osteo-stroma-osteoblast_precursor|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

LIFR COL11A1 SLC7A10 CNTN1

1.19e-0419159498b907f8fa024cf32e462323b782c5a371327bbd
ToppCelldroplet-Lung-30m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l49|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

STARD13 EPDR1 SLC7A10 CNTN1

1.22e-04192594ff4b728a55c2550c806c47e9ae3d057c35df8464
ToppCell(0)_Normal/No_Treatment-(3)_LEPR+_perivascular_cells|(0)_Normal/No_Treatment / Stress and Cell class

BMP1 LIFR FZD5 EPDR1

1.22e-041925947a2ad0bdae647b88e799e62767605f2f3c5a426f
ToppCelldroplet-Lung-30m-Mesenchymal-fibroblast-alveolar_fibroblast|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

STARD13 EPDR1 SLC7A10 CNTN1

1.22e-041925942d3790bd80a7f214b37094121a2a86ff16362569
ToppCellfacs-Pancreas-Endocrine-3m-Epithelial-pancreatic_acinar_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TDRD9 OSBPL7 STPG4

1.25e-04735931bd6ff9659efc43b0a596da50e325bde2f0ba8f7
ToppCellfacs-Pancreas-Endocrine-3m-Epithelial-pancreatic_acinar_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TDRD9 OSBPL7 STPG4

1.25e-04735933ac392ac46ad577c7d2c2b5e6a0a96ceb613097b
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

BMP1 NBEAL1 FZD5 EPDR1

1.29e-04195594d9694db6bf239636d1335016878c98f6ee2eb0eb
ToppCelltumor_Lung-Endothelial_cells-Stalk-like_ECs|Endothelial_cells / Location, Cell class and cell subclass

LIFR BMPR2 CAPZA2 EPDR1

1.29e-0419559456f88ce95495260360bf08f9c76cc36e395dc6a9
ToppCellMid-temporal_gyrus_(MTG)-Neuronal|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GABRG2 KIAA1549L KCNB2 CNTN1

1.32e-04196594676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCellTracheal-NucSeq-Epithelial-Epi_submucosal-gland-Myoepithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

LIFR COL11A1 ARHGAP20 CNTN1

1.34e-04197594f0475ad9c09c6da418dba17d3d3c1aaa2ef9ab4e
ToppCellTracheal-10x5prime-Stromal-Peri/Epineurial_|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

STARD13 CPA6 COL11A1 CNTN1

1.34e-041975942cb1f557ce1400398975de94638126b4522567f3
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GABRG2 KIAA1549L KCNB2 CNTN1

1.37e-041985940ff30edfd3c133a42e8cb96e1631a1143215f808
ToppCellTracheal-10x5prime-Stromal-Peri/Epineurial_-NAF_endoneurial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

STARD13 COL11A1 PLEKHB1 CNTN1

1.37e-041985947a0c4dbc8c99968d42af00a718f4fedc544599ec
ToppCellTracheal-10x5prime-Stromal-Peri/Epineurial_-NAF_epineurial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

STARD13 CPA6 COL11A1 SH3PXD2A

1.40e-04199594fbec5c034576cb1adaf05f6f97cc5525d19e0c1b
ToppCell10x5'v1-week_14-16-Mesenchymal_adipo-stroma|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

LIFR COL11A1 SLC7A10 CNTN1

1.40e-041995949b2262edbdec89166d895ab97527e0ee5f9b6010
ToppCell10x5'v1-week_14-16-Mesenchymal_adipo|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

LIFR COL11A1 SLC7A10 CNTN1

1.40e-04199594251b3643dcd8f4645b17101bd716e66f12a20e88
ToppCell10x5'v1-week_14-16-Mesenchymal_adipo-stroma-adipo-CAR|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

LIFR COL11A1 SLC7A10 CNTN1

1.40e-04199594117f4f43b6c06dda553799b1063e827bce697370
ToppCellSepsis-URO-Lymphocyte-T/NK-CD4+_Tcm|URO / Disease, condition lineage and cell class

ARHGAP15 NBEAL1 CACNA1I PLEKHB1

1.42e-042005944689fd4c6e7f078d7e91783a1646dd85c03cba77
ToppCellNeuronal|World / cells hierarchy compared to all cells using T-Statistic

GABRG2 KIAA1549L KCNB2 CNTN1

1.42e-0420059448d801219bc771d6c7e151dc88ca4c179988de85
ToppCellHippocampus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)|Hippocampus / BrainAtlas - Mouse McCarroll V32

CPA6 APAF1 AHNAK2

1.46e-0477593a799ccdb84014e978d9fbccf3d2fee8fbeac7b0c
DrugEtomidate

GABRE GABRG2 CACNA1I

2.55e-0611583ctd:D005045
DrugCS412

IARS2 IARS1

6.38e-062582CID006441080
DrugEdeine D

CPA6 CPB1

6.38e-062582CID000170400
DrugEdeine F

CPA6 CPB1

6.38e-062582CID000194407
DrugEserine sulfate, physostigmine sulfate [64-47-1]; Up 200; 6.2uM; MCF7; HT_HG-U133A

BMP1 COL11A1 SLC6A16 TAF1C CACNA1I CREBBP

1.11e-051985862768_UP
DrugPipemidic acid [51940-44-4]; Up 200; 13.2uM; HL60; HT_HG-U133A

STARD13 SH3PXD2A TAF1C DLG4 CPB1 CNTN1

1.11e-051985863093_UP
DrugBenzodiazepines

GABRE GABRG2

1.91e-053582ctd:D001569
Drugbeta-methylnorleucine

IARS2 IARS1

3.81e-054582CID000168760
DrugPropofol

GABRE GABRG2 APAF1 CACNA1I

4.24e-0576584ctd:D015742
DrugL-Isoleucine

IARS2 IARS1

6.35e-055582DB00167
Drugethyl bromacetate

CPA6 CPB1

6.35e-055582CID000007748
DrugNSC-333758

CPA6 CPB1

9.50e-056582CID000100086
DrugSQ24798

CPA6 CPB1

1.33e-047582CID000194328
Drughistargin

CPA6 CPB1

1.33e-047582CID000146414
DrugTsCl

CPA6 CPB1

1.33e-047582CID000007397
DrugGly-Gly-Arg

CPA6 CPB1

1.33e-047582CID000133469
DrugLithocholic acid [434-13-9]; Up 200; 10.6uM; PC3; HT_HG-U133A

KANSL1L OSBPL7 DLG4 OSBP2 SLC7A10

1.36e-041945853816_UP
DrugLobelanidine hydrochloride [6112-86-3]; Up 200; 10.6uM; MCF7; HT_HG-U133A

KANSL1L DNAI2 CACNA1I FAM131A CNTN1

1.39e-041955852897_UP
DrugFluvoxamine maleate [61718-82-9]; Up 200; 9.2uM; MCF7; HT_HG-U133A

MMP25 BMP1 SLC6A16 TAF1C AHNAK2

1.42e-041965854114_UP
DrugAvermectin B1 [71751-41-2]; Down 200; 4.8uM; HL60; HT_HG-U133A

MMP25 KANSL1L BMP1 BMPR2 SH3PXD2A

1.42e-041965852519_DN
DrugMethimazole [60-56-0]; Up 200; 35uM; MCF7; HT_HG-U133A

MMP25 LIFR APAF1 CNTN1 AHNAK2

1.42e-041965854372_UP
DrugIsoflurane

APAF1 DLG4 CACNA1I NCSTN

1.44e-04104584ctd:D007530
Drugsulindac sulfide; Down 200; 50uM; MCF7; HG-U133A

BMP1 APAF1 CPB1 GPATCH2L CNTN1

1.46e-04197585308_DN
DrugChlorhexidine [55-56-1]; Up 200; 8uM; MCF7; HT_HG-U133A

MMP25 KANSL1L TAF1C CACNA1I CREBBP

1.46e-041975855403_UP
Drugrofecoxib; Down 200; 10uM; MCF7; HG-U133A

BMP1 BMPR2 APAF1 OSBPL7 CACNA1I

1.46e-04197585256_DN
DrugRetrorsine [480-54-6]; Up 200; 11.4uM; HL60; HT_HG-U133A

BMPR2 SH3PXD2A APAF1 FAM131A CREBBP

1.46e-041975852129_UP
DrugPinacidil [85371-64-8]; Up 200; 16.4uM; MCF7; HT_HG-U133A

APAF1 DNAI2 CREBBP SLC7A10 AHNAK2

1.46e-041975855456_UP
DrugMeclofenoxate hydrochloride [3685-84-5]; Up 200; 13.6uM; MCF7; HT_HG-U133A

KANSL1L BMP1 OSBP2 CREBBP CNTN1

1.46e-041975854729_UP
Drug3-Acetylcoumarin [3949-36-8]; Up 200; 21.2uM; MCF7; HT_HG-U133A

BMP1 DNAI2 OSBPL7 CACNA1I CNTN1

1.46e-041975853382_UP
Drug2-Chloropyrazine [14508-49-7]; Up 200; 35uM; PC3; HT_HG-U133A

MMP25 KANSL1L SH3PXD2A CACNA1I PLEKHB1

1.46e-041975855750_UP
DrugAdrenosterone [382-45-6]; Up 200; 13.4uM; MCF7; HT_HG-U133A

BMP1 TAF1C DNAI2 CREBBP GPATCH2L

1.49e-041985855464_UP
DrugFlunixin meglumine [42461-84-7]; Up 200; 8.2uM; PC3; HT_HG-U133A

KANSL1L COL11A1 SLC6A16 DNAI2 CACNA1I

1.49e-041985854273_UP
Drugfluphenazine dihydrochloride; Down 200; 10uM; HL60; HT_HG-U133A

KANSL1L SH3PXD2A TAF1C DNAI2 FAM131A

1.49e-041985856196_DN
DrugVancomycin hydrochloride [1404-93-9]; Up 200; 2.6uM; HL60; HT_HG-U133A

BMP1 BMPR2 SH3PXD2A DNAI2 CACNA1I

1.53e-041995852498_UP
DrugICI182,780; Up 200; 1uM; MCF7; HT_HG-U133A

MMP25 KANSL1L BMP1 GPATCH2L AHNAK2

1.53e-041995856872_UP
DrugProgesterone [57-83-0]; Up 200; 12.8uM; MCF7; HT_HG-U133A

BMP1 DNAI2 CACNA1I CPB1 AHNAK2

1.53e-041995853287_UP
DrugSQ 14,603

CPA6 CPB1

1.77e-048582CID000194327
DrugCck-gly

CPA6 CPB1

1.77e-048582CID000195414
DrugNSC 116328

IARS2 IARS1

1.77e-048582CID000073423
Drugphenylalanine

CPA6 IARS2 IARS1 CAPZA2 NSMAF

1.88e-04208585CID000000994
DrugCGP 36742

GABRG2 DLG4 NCSTN

1.93e-0444583CID000130021
DrugPentobarbital

GABRE GABRG2 APAF1 CACNA1I

2.12e-04115584ctd:D010424
Drugvalyl adenylate

IARS2 IARS1

2.27e-049582CID000189137
Drugp-guanidino-L-phenylalanine

CPA6 CPB1

2.27e-049582CID000165028
Drugguanidinopropylsuccinic acid

CPA6 CPB1

2.27e-049582CID000127548
DrugMTX-Ala

CPA6 CPB1

2.27e-049582CID005489429
DrugN-NBD-PE

NEU1 CPB1

2.27e-049582CID000127398
DrugSP-Gly

CPA6 CPB1

2.27e-049582CID000163663
DiseaseAngle Closure Glaucoma

COL11A1 EPDR1

7.38e-057562C0017605
Diseaseprimary angle closure glaucoma

COL11A1 EPDR1

1.92e-0411562EFO_1001506
Diseasep-cresol sulfate measurement

STARD13 CAPZA2

4.17e-0416562EFO_0010998
Diseaseobese body mass index status

KIAA1549L ADCY3

1.80e-0333562EFO_0007041

Protein segments in the cluster

PeptideGeneStartEntry
SRLLSWSFDGTVKVW

APAF1

1056

O14727
WSDRKSARSYETWIG

EPDR1

151

Q9UM22
LLTWVNSSSVRWATR

SLC7A10

171

Q9NS82
DRWFSTWIGASIVTS

ACTRT2

336

Q8TDY3
PDWWQVRKLKSSSSS

BMX

241

P51813
WEFSSLRRSKWSTLC

CREBBP

1676

Q92793
WTARIWSEDSRESSI

DNAI2

386

Q9GZS0
RLWVEFRSSSNWVGK

BMP1

411

P13497
SWTNDRFWRKTRSRN

CPA6

246

Q8N4T0
IYTWTTDRLWRKSRS

CPO

156

Q8IVL8
RTWKTWTTADFRTKK

AKAP8L

261

Q9ULX6
DWLVWTSTKASESRL

NBEAL1

911

Q6ZS30
STWTESRWKDIRARI

NCSTN

646

Q92542
SGSVWKKRTLTWRVR

MMP25

111

Q9NPA2
STEWKWLVDRARVGS

KANSL1L

366

A0AUZ9
SRYSQTSTWKLASVW

LSM11

251

P83369
TSTWKLASVWGRADT

LSM11

256

P83369
SRWKTKRWLWDFTVT

COL11A1

6

P12107
WVSFWIKTESAPART

GABRE

296

P78334
TSWTFPRWKKDSVTA

KIAA1549L

256

Q6ZVL6
WSLWQEITISSKFRG

OSBP2

641

Q969R2
IWSGKTVESWRRFTS

FZD5

521

Q13467
RWKWARKALSETSSN

KCNB2

491

Q92953
SFWRIWSRSELKTVP

BFAR

376

Q9NZS9
SAAWASRRSSWNSLK

CACNA1I

981

Q9P0X4
FSWSKGTEWLVNSSR

CNTN1

446

Q12860
QWKRSSVEVGDTRSW

GABRG2

221

P18507
LKRWRPSTWVISTES

BMPR2

981

Q13873
TSRRVSSDPAWAVEW

FAM131A

26

Q6UXB0
LVAFSTWIDRTRWAR

ADCY3

691

O60266
RREWSRLKAKDWGSS

DLG4

496

P78352
RLYSASWDSTVKVWS

NSMAF

726

Q92636
QRLSRWKENTPWTSS

GPATCH2L

166

Q9NWQ4
EWISSETSALPRSRW

DCAF8L1

141

A6NGE4
PRRKWDSSISEKTAW

CCDC168

2101

Q8NDH2
DRSSRLSEAWKWRLS

PPP1R18

181

Q6NYC8
TWTKSRFWRKTRSTH

CPB1

226

P15086
TFRIRCSTETFWKWS

LIFR

506

P42702
FRRQTDSSGKEWWVT

OSBPL7

806

Q9BZF2
RRSIINWAFWRGSST

ARHGAP20

331

Q9P2F6
SNKWTFQRTSRRWSR

STARD13

141

Q9Y3M8
TWEDKGSLTRSATSW

SLC6A16

31

Q9GZN6
GASSIARWISKERAW

TDRD9

191

Q8NDG6
DPETLVFRDSSSWRW

TAF1C

376

Q15572
RSESVWTTTPRSNWE

PIRT

36

P0C851
EKRVSVRWSADGWRS

PPP1R3E

186

Q9H7J1
LRWSFSNGTSWRKET

NEU1

346

Q99519
NWSTSWIVLSSRRIE

ARHGAP15

101

Q53QZ3
WKSTVSRLGRWIDFD

IARS1

131

P41252
KSVFRTGWISTSSIW

IARS2

856

Q9NSE4
SRLRLWTKWVFAGVS

SLC28A2

141

O43868
SWWKRDSGDSRTFFR

AHNAK2

86

Q8IVF2
GRWRSEWKFTITPST

CAPZA2

171

P47755
VTRSWSPCKVERRIW

PLEKHB1

151

Q9UF11
GSSKRKSVWLSSWAE

SH3PXD2A

136

Q5TCZ1
QKTSSFEREGWWRIA

STPG4

31

Q8N801
RPWSVEEIRRSSQSW

WASHC2C

21

Q9Y4E1
RKWSRFTRSSFQVRW

nan

86

Q6ZVQ6
LWKTRDSGTVSALTW

SLC66A3

136

Q8N755
RPWSVEEIRRSSQSW

WASHC2A

21

Q641Q2
SASRWKIPSSWRLLF

PSMG2

241

Q969U7